-
1
-
-
0036086130
-
Free radicals in the physiological control of cell function
-
Droge, W. 2002. Free radicals in the physiological control of cell function. Physiol. Rev. 82:47.
-
(2002)
Physiol. Rev.
, vol.82
, pp. 47
-
-
Droge, W.1
-
2
-
-
0036911138
-
Hydrogen peroxide as second messenger in lymphocyte activation
-
Reth, M. 2002. Hydrogen peroxide as second messenger in lymphocyte activation. Nat. Immunol. 3:1129.
-
(2002)
Nat. Immunol.
, vol.3
, pp. 1129
-
-
Reth, M.1
-
3
-
-
0023903097
-
Oxidative phenomena are implicated in human T-cell stimulation
-
Sekkat, C., J. Dornand, and M. Gerber. 1988. Oxidative phenomena are implicated in human T-cell stimulation. Immunology 63:431.
-
(1988)
Immunology
, vol.63
, pp. 431
-
-
Sekkat, C.1
Dornand, J.2
Gerber, M.3
-
4
-
-
0030587124
-
Role of reactive oxygen intermediates in TCR-induced death of T cell blasts and hybridomas
-
Williams, M. S., and P. A. Henkart. 1996. Role of reactive oxygen intermediates in TCR-induced death of T cell blasts and hybridomas. J. Immunol. 157:2395.
-
(1996)
J. Immunol.
, vol.157
, pp. 2395
-
-
Williams, M.S.1
Henkart, P.A.2
-
5
-
-
0029164695
-
IL-2 gene expression and NF-κB activation through CD28 requires reactive oxygen production by 5-lipoxygenase
-
Los, M., H. Schenk, K. Hexel, P. A. Baeuerle, W. Droge, and K. Schulze-Osthoff. 1995. IL-2 gene expression and NF-κB activation through CD28 requires reactive oxygen production by 5-lipoxygenase. EMBO J. 14:3731.
-
(1995)
EMBO J.
, vol.14
, pp. 3731
-
-
Los, M.1
Schenk, H.2
Hexel, K.3
Baeuerle, P.A.4
Droge, W.5
Schulze-Osthoff, K.6
-
6
-
-
0028929973
-
A signaling pathway coupled to T cell receptor ligation by MMTV superantigen leading to transient activation and programmed cell death
-
Weber, G. F., S. Abromson-Leeman, and H. Cantor. 1995. A signaling pathway coupled to T cell receptor ligation by MMTV superantigen leading to transient activation and programmed cell death. Immunity 2:363.
-
(1995)
Immunity
, vol.2
, pp. 363
-
-
Weber, G.F.1
Abromson-Leeman, S.2
Cantor, H.3
-
7
-
-
0033151622
-
Reactive oxygen species regulate activation-induced T cell apoptosis
-
Hildeman, D. A., T. Mitchell, T. K. Teague, P. Henson, B. J. Day, J. Kappler, and P. C. Marrack. 1999. Reactive oxygen species regulate activation-induced T cell apoptosis. Immunity 10:735.
-
(1999)
Immunity
, vol.10
, pp. 735
-
-
Hildeman, D.A.1
Mitchell, T.2
Teague, T.K.3
Henson, P.4
Day, B.J.5
Kappler, J.6
Marrack, P.C.7
-
8
-
-
0037033433
-
Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: Selective regulation of mitogen-activated protein kinase activation and Fas ligand expression
-
Devadas, S., L. Zaritskaya, S. G. Rhee, L. Oberley, and M. S. Williams. 2002. Discrete generation of superoxide and hydrogen peroxide by T cell receptor stimulation: selective regulation of mitogen-activated protein kinase activation and Fas ligand expression. J. Exp. Med. 195:59.
-
(2002)
J. Exp. Med.
, vol.195
, pp. 59
-
-
Devadas, S.1
Zaritskaya, L.2
Rhee, S.G.3
Oberley, L.4
Williams, M.S.5
-
9
-
-
0028318891
-
Thiol-mediated redox regulation of lymphocyte proliferation: Possible involvement of adult T cell leukemia-derived factor and glutathione in transferrin receptor expression
-
Iwata, S., T. Hori, N. Sato, Y. Ueda-Taniguchi, T. Yamabe, H. Nakamura, H. Masutani, and J. Yodoi. 1994. Thiol-mediated redox regulation of lymphocyte proliferation: possible involvement of adult T cell leukemia-derived factor and glutathione in transferrin receptor expression. J. Immunol. 152:5633.
-
(1994)
J. Immunol.
, vol.152
, pp. 5633
-
-
Iwata, S.1
Hori, T.2
Sato, N.3
Ueda-Taniguchi, Y.4
Yamabe, T.5
Nakamura, H.6
Masutani, H.7
Yodoi, J.8
-
10
-
-
0036019930
-
Redox control of T-cell death
-
Nakashima, I., H. Suzuki, M. Kato, and A. A. Akhand. 2002. Redox control of T-cell death. Antioxid. Redox Signal. 4:353.
-
(2002)
Antioxid. Redox Signal.
, vol.4
, pp. 353
-
-
Nakashima, I.1
Suzuki, H.2
Kato, M.3
Akhand, A.A.4
-
11
-
-
0025077481
-
Redox regulation of Fos and Jun DNA-binding activity in vitro
-
Abate, C., L. Patel, F. J. Rauscher, III, and T. Curran. 1990. Redox regulation of Fos and Jun DNA-binding activity in vitro. Science 249:1157.
-
(1990)
Science
, vol.249
, pp. 1157
-
-
Abate, C.1
Patel, L.2
Rauscher F.J. III3
Curran, T.4
-
12
-
-
0030936568
-
AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1
-
Hirota, K., M. Matsui, S. Iwata, A. Nishiyama, K. Mori, and J. Yodoi, 1997. AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1. Proc. Natl. Acad. Sci. USA 94:3633.
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 3633
-
-
Hirota, K.1
Matsui, M.2
Iwata, S.3
Nishiyama, A.4
Mori, K.5
Yodoi, J.6
-
13
-
-
0027217531
-
Oxidoreductive regulation of nuclear factor kB: Involvement of a cellular reducing catalyst thioredoxin
-
Hayashi, T., Y. Ueno, and T. Okamoto. 1993. Oxidoreductive regulation of nuclear factor kB: involvement of a cellular reducing catalyst thioredoxin. J. Biol. Chem. 268:11380.
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 11380
-
-
Hayashi, T.1
Ueno, Y.2
Okamoto, T.3
-
14
-
-
0028344541
-
Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-κB and AP-1
-
Schenk, H., M. Klein, W. Erdbrugger, W. Droge, and K. Schulze-Osthoff. 1994. Distinct effects of thioredoxin and antioxidants on the activation of transcription factors NF-κB and AP-1. Proc. Natl. Acad. Sci. USA 91:1672.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 1672
-
-
Schenk, H.1
Klein, M.2
Erdbrugger, W.3
Droge, W.4
Schulze-Osthoff, K.5
-
16
-
-
0036193746
-
Oxidants painting the cysteine chapel: Redox regulation of PTPs
-
Xu, D., I. I. Rovira, and T. Finkel. 2002. Oxidants painting the cysteine chapel: redox regulation of PTPs. Dev. Cell 2:251.
-
(2002)
Dev. Cell
, vol.2
, pp. 251
-
-
Xu, D.1
Rovira, I.I.2
Finkel, T.3
-
17
-
-
0032521428
-
Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2
-
Barford, D., and B. G. Neel. 1998. Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2. Structure 6:249.
-
(1998)
Structure
, vol.6
, pp. 249
-
-
Barford, D.1
Neel, B.G.2
-
18
-
-
0036184190
-
Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo
-
Meng, T. C., T. Fukada, and N. K. Tonks. 2002. Reversible oxidation and inactivation of protein tyrosine phosphatases in vivo. Mol. Cell. 9:387.
-
(2002)
Mol. Cell.
, vol.9
, pp. 387
-
-
Meng, T.C.1
Fukada, T.2
Tonks, N.K.3
-
20
-
-
0032546352
-
Dendritic cells and the control of immunity
-
Banchereau, J., and R. M. Steinman. 1998. Dendritic cells and the control of immunity. Nature 392:245.
-
(1998)
Nature
, vol.392
, pp. 245
-
-
Banchereau, J.1
Steinman, R.M.2
-
21
-
-
0037022345
-
Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation
-
Angelini, G., S. Gardella, M. Ardy, M. R. Ciriolo, G. Filomeni, G. Di Trapani, F. Clarke, R. Sitia, and A. Rubartelli. 2002. Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation. Proc. Natl. Acad. Sci. USA 99:1491.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 1491
-
-
Angelini, G.1
Gardella, S.2
Ardy, M.3
Ciriolo, M.R.4
Filomeni, G.5
Di Trapani, G.6
Clarke, F.7
Sitia, R.8
Rubartelli, A.9
-
22
-
-
0028871442
-
T cell-dependent loss of proliferative responsiveness to colony-stimulating factor-1 by a murine epidermal-derived dendritic cell line, XS52
-
Kitajima, T., K. Ariizumi, P. R. Bergstresser, and A. Takashima. 1995. T cell-dependent loss of proliferative responsiveness to colony-stimulating factor-1 by a murine epidermal-derived dendritic cell line, XS52. J. Immunol. 155:5190.
-
(1995)
J. Immunol.
, vol.155
, pp. 5190
-
-
Kitajima, T.1
Ariizumi, K.2
Bergstresser, P.R.3
Takashima, A.4
-
23
-
-
0029112642
-
T cell-dependent secretion of IL-1β by a dendritic cell line (XS52) derived from murine epidermis
-
Kitajima, T., K. Ariizumi, M. Mohamadzadeh, D. Edelbaum, P. R. Bergstresser, and A. Takashima. 1995. T cell-dependent secretion of IL-1β by a dendritic cell line (XS52) derived from murine epidermis. J. Immunol. 155:3794.
-
(1995)
J. Immunol.
, vol.155
, pp. 3794
-
-
Kitajima, T.1
Ariizumi, K.2
Mohamadzadeh, M.3
Edelbaum, D.4
Bergstresser, P.R.5
Takashima, A.6
-
24
-
-
0030587136
-
T cell-mediated terminal maturation of dendritic cells: Loss of adhesive and phagocytotic capacities
-
Kitajima, T., G. Caceres-Dittmar, F. J. Tapia, J. Jester, P. R. Bergstresser, and A. Takashima. 1996. T cell-mediated terminal maturation of dendritic cells: loss of adhesive and phagocytotic capacities. J. Immunol. 157:2340.
-
(1996)
J. Immunol.
, vol.157
, pp. 2340
-
-
Kitajima, T.1
Caceres-Dittmar, G.2
Tapia, F.J.3
Jester, J.4
Bergstresser, P.R.5
Takashima, A.6
-
25
-
-
0030015768
-
A novel mechanism of glucocorticoid-induced immune suppression: The inhibition of T cell-mediated terminal maturation of a murine dendritic cell line
-
Kitajima, T., K. Ariizumi, P. R. Bergstresser, and A. Takashima. 1996. A novel mechanism of glucocorticoid-induced immune suppression: the inhibition of T cell-mediated terminal maturation of a murine dendritic cell line. J. Clin. Invest. 98:142.
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 142
-
-
Kitajima, T.1
Ariizumi, K.2
Bergstresser, P.R.3
Takashima, A.4
-
26
-
-
0036784638
-
Contrasting impacts of immunosuppressive agents (rapamycin, FK506, cyclosporin A, and dexamethasone) on bidirectional dendritic cell-T cell interaction during antigen presentation
-
Matsue, H., C. Yang, K. Matsue, D. Edelbaum, M. E. Mummert, and A. Takashima. 2002. Contrasting impacts of immunosuppressive agents (rapamycin, FK506, cyclosporin A, and dexamethasone) on bidirectional dendritic cell-T cell interaction during antigen presentation. J. Immunol. 169:3555.
-
(2002)
J. Immunol.
, vol.169
, pp. 3555
-
-
Matsue, H.1
Yang, C.2
Matsue, K.3
Edelbaum, D.4
Mummert, M.E.5
Takashima, A.6
-
27
-
-
0021185122
-
A novel biologically active seleno-organic compound-I: Glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ51 (ebselen)
-
Muller, A., E. Cadenas, P. Graf, and H. Sies. 1984. A novel biologically active seleno-organic compound-I: glutathione peroxidase-like activity in vitro and antioxidant capacity of PZ51 (ebselen). Biochem. Pharmacol. 33:3235.
-
(1984)
Biochem. Pharmacol.
, vol.33
, pp. 3235
-
-
Muller, A.1
Cadenas, E.2
Graf, P.3
Sies, H.4
-
28
-
-
0037172997
-
Ebselen: A substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant
-
Zhao, R., H. Masayasu, and A. Holmgren. 2002. Ebselen: a substrate for human thioredoxin reductase strongly stimulating its hydroperoxide reductase activity and a superfast thioredoxin oxidant. Proc. Natl. Acad. Sci. USA 99:8579.
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 8579
-
-
Zhao, R.1
Masayasu, H.2
Holmgren, A.3
-
29
-
-
0037131424
-
A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase
-
Zhao, R., and A. Holmgren. 2002. A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase. J. Biol. Chem. 277:39456.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39456
-
-
Zhao, R.1
Holmgren, A.2
-
30
-
-
0028136243
-
Strong inhibition of mammalian lipoxygenases by the antiinflammatory seleno-organic compound ebselen in the absence of glutathione
-
Schewe, C., T. Schewe, and A. Wendel. 1994. Strong inhibition of mammalian lipoxygenases by the antiinflammatory seleno-organic compound ebselen in the absence of glutathione. Biochem. Pharmacol. 48:65.
-
(1994)
Biochem. Pharmacol.
, vol.48
, pp. 65
-
-
Schewe, C.1
Schewe, T.2
Wendel, A.3
-
31
-
-
0028180046
-
Preferential inhibition of inducible nitric oxide synthase by ebselen
-
Hattori, R., R. Inoue, K. Sase, H. Eizawa, K. Kosuga, T. Aoyama, H. Masayasu, C. Kawai, S. Sasayama, and Y. Yui. 1994. Preferential inhibition of inducible nitric oxide synthase by ebselen. Eur. J. Pharmacol. 267:R1.
-
(1994)
Eur. J. Pharmacol.
, vol.267
-
-
Hattori, R.1
Inoue, R.2
Sase, K.3
Eizawa, H.4
Kosuga, K.5
Aoyama, T.6
Masayasu, H.7
Kawai, C.8
Sasayama, S.9
Yui, Y.10
-
32
-
-
0024559124
-
Studies on the anti-inflammatory activity of ebselen: Ebselen interferes with granulocyte oxidative burst by dual inhibition of NADPH oxidase and protein kinase C
-
Cotgreave, I. A., S. K. Duddy, G. E. Kass, D. Thompson, and P. Moldeus. 1989. Studies on the anti-inflammatory activity of ebselen: ebselen interferes with granulocyte oxidative burst by dual inhibition of NADPH oxidase and protein kinase C. Biochem. Pharmacol. 38:649.
-
(1989)
Biochem. Pharmacol.
, vol.38
, pp. 649
-
-
Cotgreave, I.A.1
Duddy, S.K.2
Kass, G.E.3
Thompson, D.4
Moldeus, P.5
-
34
-
-
0028934348
-
Successive generation of antigen-presenting, dendritic cell lines from murine epidermis
-
Xu, S., K. Ariizumi, G. Caceres-Dittmar, D. Edelbaum, K. Hashimoto, P. R. Bergstresser, and A. Takashima. 1995. Successive generation of antigen-presenting, dendritic cell lines from murine epidermis. J. Immunol. 154:2697.
-
(1995)
J. Immunol.
, vol.154
, pp. 2697
-
-
Xu, S.1
Ariizumi, K.2
Caceres-Dittmar, G.3
Edelbaum, D.4
Hashimoto, K.5
Bergstresser, P.R.6
Takashima, A.7
-
35
-
-
0029014954
-
Colony-stimulating factor-1 secreted by fibroblasts promotes the growth of dendritic cell lines (XS series) derived from murine epidermis
-
Takashima, A., D. Edelbaum, T. Kitajima, R. K. Shadduck, G. L. Gilmore, S. Xu, R. S. Taylor, P. R. Bergstresser, and K. Ariizumi. 1995. Colony-stimulating factor-1 secreted by fibroblasts promotes the growth of dendritic cell lines (XS series) derived from murine epidermis. J. Immunol. 154:5128.
-
(1995)
J. Immunol.
, vol.154
, pp. 5128
-
-
Takashima, A.1
Edelbaum, D.2
Kitajima, T.3
Shadduck, R.K.4
Gilmore, G.L.5
Xu, S.6
Taylor, R.S.7
Bergstresser, P.R.8
Ariizumi, K.9
-
36
-
-
0037108377
-
Synthesis and surface expression of hyaluronan by dendritic cells and its potential role in antigen presentation
-
Mummert, M. E., D. Mummert, D. Edelbaum, F. Hui, H. Matsue, and A. Takashima. 2002. Synthesis and surface expression of hyaluronan by dendritic cells and its potential role in antigen presentation. J. Immunol. 169:4322.
-
(2002)
J. Immunol.
, vol.169
, pp. 4322
-
-
Mummert, M.E.1
Mummert, D.2
Edelbaum, D.3
Hui, F.4
Matsue, H.5
Takashima, A.6
-
37
-
-
0033557718
-
Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma
-
Randolph, D. A., C. J. L. Carruthers, S. J. Szabo, K. M. Murphy, and D. D. Chaplin. 1999. Modulation of airway inflammation by passive transfer of allergen-specific Th1 and Th2 cells in a mouse model of asthma. J. Immunol. 162:2375.
-
(1999)
J. Immunol.
, vol.162
, pp. 2375
-
-
Randolph, D.A.1
Carruthers, C.J.L.2
Szabo, S.J.3
Murphy, K.M.4
Chaplin, D.D.5
-
38
-
-
0032790004
-
Induction of antigen-specific immunosuppression by CD95L cDNA-transfected "killer" dendritic cells
-
Matsue, H., K. Matsue, M. Walters, K. Okumura, H. Yagita, and A. Takashima. 1999. Induction of antigen-specific immunosuppression by CD95L cDNA-transfected "killer" dendritic cells. Nat. Med. 5:930.
-
(1999)
Nat. Med.
, vol.5
, pp. 930
-
-
Matsue, H.1
Matsue, K.2
Walters, M.3
Okumura, K.4
Yagita, H.5
Takashima, A.6
-
39
-
-
0036139893
-
Induction of tumor-specific protective immunity by in situ Langerhans cell vaccine
-
Kumamoto, T., E. K. Huang, H. J. Paek, A. Morita, H. Matsue, R. F. Valentini, and A. Takashima. 2002. Induction of tumor-specific protective immunity by in situ Langerhans cell vaccine. Nat. Biotechnol. 20:64.
-
(2002)
Nat. Biotechnol.
, vol.20
, pp. 64
-
-
Kumamoto, T.1
Huang, E.K.2
Paek, H.J.3
Morita, A.4
Matsue, H.5
Valentini, R.F.6
Takashima, A.7
-
40
-
-
0026481133
-
Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor
-
Inaba, K., M. Inaba, N. Romani, H. Aya, M. Deguchi, S. Ikehara, S. Muramatsu, and R. M. Steinman. 1992. Generation of large numbers of dendritic cells from mouse bone marrow cultures supplemented with granulocyte/macrophage colony-stimulating factor. J. Exp. Med. 176:1693.
-
(1992)
J. Exp. Med.
, vol.176
, pp. 1693
-
-
Inaba, K.1
Inaba, M.2
Romani, N.3
Aya, H.4
Deguchi, M.5
Ikehara, S.6
Muramatsu, S.7
Steinman, R.M.8
-
41
-
-
0033806427
-
Development of a peptide inhibitor of hyaluronan-mediated leukocyte trafficking
-
Mummert, M. E., M. Mohamadzadeh, D. I. Mummert, N. Mizumoto, and A. Takashima. 2000. Development of a peptide inhibitor of hyaluronan-mediated leukocyte trafficking. J. Exp. Med. 192:769.
-
(2000)
J. Exp. Med.
, vol.192
, pp. 769
-
-
Mummert, M.E.1
Mohamadzadeh, M.2
Mummert, D.I.3
Mizumoto, N.4
Takashima, A.5
-
42
-
-
0036102125
-
CD39 is the dominant Langerhans cell-associated ecto-NTPDase: Modulatory roles in inflammation and immune responsiveness
-
Mizumoto, N., T. Kumamoto, S. C. Robson, J. Sévigny, H. Matsue, K. Enjyoji, and A. Takashima. 2002. CD39 is the dominant Langerhans cell-associated ecto-NTPDase: modulatory roles in inflammation and immune responsiveness. Nat. Med. 8:358.
-
(2002)
Nat. Med.
, vol.8
, pp. 358
-
-
Mizumoto, N.1
Kumamoto, T.2
Robson, S.C.3
Sévigny, J.4
Matsue, H.5
Enjyoji, K.6
Takashima, A.7
-
43
-
-
0027221887
-
The effect of ebselen on polymorphonuclear leukocyte and lymphocyte migration to inflammatory reactions in rats
-
Gao, J. X., and A. C. Issekutz. 1993. The effect of ebselen on polymorphonuclear leukocyte and lymphocyte migration to inflammatory reactions in rats. Immunopharmacology 25:239.
-
(1993)
Immunopharmacology
, vol.25
, pp. 239
-
-
Gao, J.X.1
Issekutz, A.C.2
-
44
-
-
0027369597
-
The effect of ebselen on polymorphonuclear leukocyte migration to joints in rats with adjuvant arthritis
-
Gao, J. X., and A. C. Issekutz. 1993. The effect of ebselen on polymorphonuclear leukocyte migration to joints in rats with adjuvant arthritis. Int. J. Immunopharmacol. 15:793.
-
(1993)
Int. J. Immunopharmacol.
, vol.15
, pp. 793
-
-
Gao, J.X.1
Issekutz, A.C.2
-
45
-
-
0037100440
-
Differential effects of ebselen on neutrophil recruitment, chemokine, and inflammatory mediator expression in a rat model of lipopolysaccharide-induced pulmonary inflammation
-
Haddad, E., K. McCluskie, M. A. Birrell, D. Dabrowski, M. Pecoraro, S. Underwood, B. Chen, G. T. De Sanctis, S. E. Webber, M. L. Foster, and M. G. Belvisi. 2002. Differential effects of ebselen on neutrophil recruitment, chemokine, and inflammatory mediator expression in a rat model of lipopolysaccharide-induced pulmonary inflammation. J. Immunol. 169:974.
-
(2002)
J. Immunol.
, vol.169
, pp. 974
-
-
Haddad, E.1
McCluskie, K.2
Birrell, M.A.3
Dabrowski, D.4
Pecoraro, M.5
Underwood, S.6
Chen, B.7
De Sanctis, G.T.8
Webber, S.E.9
Foster, M.L.10
Belvisi, M.G.11
-
46
-
-
0034769118
-
Nitric oxide and the immune response
-
Bogdan, C. 2001. Nitric oxide and the immune response. Nat. Immunol. 2:907.
-
(2001)
Nat. Immunol.
, vol.2
, pp. 907
-
-
Bogdan, C.1
-
47
-
-
0033866907
-
Selenoorganic compound, ebselen, inhibits nitric oxide and tumor necrosis factor-alpha production by the modulation of Jun-N-terminal kinase and the NF-κB signaling pathway in rat Kupffer cells
-
Shimohashi, N., M. Nakamuta, K. Uchimura, R. Sugimoto, H. Iwamoto, M. Enjoji, and H. Nawata. 2000. Selenoorganic compound, ebselen, inhibits nitric oxide and tumor necrosis factor-alpha production by the modulation of Jun-N-terminal kinase and the NF-κB signaling pathway in rat Kupffer cells. J. Cell. Biochem. 78:595.
-
(2000)
J. Cell. Biochem.
, vol.78
, pp. 595
-
-
Shimohashi, N.1
Nakamuta, M.2
Uchimura, K.3
Sugimoto, R.4
Iwamoto, H.5
Enjoji, M.6
Nawata, H.7
-
48
-
-
0037169525
-
Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant. Implication for inflammation-associated carcinogenesis
-
Nakamura, Y., Q. Feng, T. Kumagai, K. Torikai, H. Ohigashi, T. Osawa, N. Noguchi, E. Niki, and K. Uchida. 2002. Ebselen, a glutathione peroxidase mimetic seleno-organic compound, as a multifunctional antioxidant. Implication for inflammation-associated carcinogenesis. J. Biol. Chem. 277:2687.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 2687
-
-
Nakamura, Y.1
Feng, Q.2
Kumagai, T.3
Torikai, K.4
Ohigashi, H.5
Osawa, T.6
Noguchi, N.7
Niki, E.8
Uchida, K.9
-
49
-
-
0032253785
-
Ebselen protects mice against T cell-dependent, TNF-mediated apoptotic liver injury
-
Tiegs, G., S. Kusters, G. Kunstle, H. Hentze, A. K. Kiemer, and A. Wendel. 1998. Ebselen protects mice against T cell-dependent, TNF-mediated apoptotic liver injury. J. Pharmacol. Exp. Ther. 287:1098.
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.287
, pp. 1098
-
-
Tiegs, G.1
Kusters, S.2
Kunstle, G.3
Hentze, H.4
Kiemer, A.K.5
Wendel, A.6
-
50
-
-
0030734080
-
Neuroprotective efficacy of ebselen, an anti-oxidant with anti-inflammatory actions, in a rodent model of permanent middle cerebral artery occlusion
-
Takasago, T., E. E. Peters, D. I. Graham, H. Masayasu, and I. M. Macrae. 1997. Neuroprotective efficacy of ebselen, an anti-oxidant with anti-inflammatory actions, in a rodent model of permanent middle cerebral artery occlusion. Br. J. Pharmacol. 122:1251.
-
(1997)
Br. J. Pharmacol.
, vol.122
, pp. 1251
-
-
Takasago, T.1
Peters, E.E.2
Graham, D.I.3
Masayasu, H.4
Macrae, I.M.5
-
51
-
-
0034884323
-
Ebselen reduces cytochrome c release from mitochondria and subsequent DNA fragmentation after transient focal cerebral ischemia in mice
-
Namura, S., I. Nagata, S. Takami, H. Masayasu, and H. Kikuchi. 2001. Ebselen reduces cytochrome c release from mitochondria and subsequent DNA fragmentation after transient focal cerebral ischemia in mice. Stroke 32:1906.
-
(2001)
Stroke
, vol.32
, pp. 1906
-
-
Namura, S.1
Nagata, I.2
Takami, S.3
Masayasu, H.4
Kikuchi, H.5
-
52
-
-
0034821411
-
Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia
-
Imai, H., H. Masayasu, D. Dewar, D. I. Graham, and I. M. Macrae. 2001. Ebselen protects both gray and white matter in a rodent model of focal cerebral ischemia. Stroke 32:2149.
-
(2001)
Stroke
, vol.32
, pp. 2149
-
-
Imai, H.1
Masayasu, H.2
Dewar, D.3
Graham, D.I.4
Macrae, I.M.5
-
53
-
-
0031963836
-
Ebselen in acute ischemic stroke: A placebo-controlled, double-blind clinical trial
-
Ebselen Study Group
-
Yamaguchi, T., K. Sano, K. Takakura, I. Saito, Y. Shinohara, T. Asano, and H. Yasuhara. 1998. Ebselen in acute ischemic stroke: a placebo-controlled, double-blind clinical trial. Ebselen Study Group. Stroke 29:12.
-
(1998)
Stroke
, vol.29
, pp. 12
-
-
Yamaguchi, T.1
Sano, K.2
Takakura, K.3
Saito, I.4
Shinohara, Y.5
Asano, T.6
Yasuhara, H.7
-
54
-
-
0031886421
-
Neuroprotective effect of an antioxidant, ebselen, in patients with delayed neurological deficits after aneurysmal subarachnoid hemorrhage
-
Saito, I., T. Asano, K. Sano, K. Takakura, H. Abe, T. Yoshimoto, H. Kikuchi, T. Ohta, and S. Ishibashi. 1998. Neuroprotective effect of an antioxidant, ebselen, in patients with delayed neurological deficits after aneurysmal subarachnoid hemorrhage. Neurosurgery 42:269.
-
(1998)
Neurosurgery
, vol.42
, pp. 269
-
-
Saito, I.1
Asano, T.2
Sano, K.3
Takakura, K.4
Abe, H.5
Yoshimoto, T.6
Kikuchi, H.7
Ohta, T.8
Ishibashi, S.9
-
55
-
-
0033698581
-
Manipulating immune responses with immunosuppressive agents that target NFAT
-
Kiani, A., A. Rao, and J. Aramburu. 2000. Manipulating immune responses with immunosuppressive agents that target NFAT. Immunity 12:359.
-
(2000)
Immunity
, vol.12
, pp. 359
-
-
Kiani, A.1
Rao, A.2
Aramburu, J.3
-
56
-
-
0033525748
-
2+, calcineurin, and NF-AT
-
2+, calcineurin, and NF-AT. Cell 96:611.
-
(1999)
Cell
, vol.96
, pp. 611
-
-
Crabtree, G.R.1
-
57
-
-
0030272487
-
Molecular mechanisms of action of new xenobiotic immunosuppressive drugs: Tacrolimus (FK506), sirolimus (rapamycin), mycophenolate mofetil and leflunomide
-
Brazelton, T. R., and R. E. Morris. 1996. Molecular mechanisms of action of new xenobiotic immunosuppressive drugs: tacrolimus (FK506), sirolimus (rapamycin), mycophenolate mofetil and leflunomide. Curr. Opin. Immunol. 8:710.
-
(1996)
Curr. Opin. Immunol.
, vol.8
, pp. 710
-
-
Brazelton, T.R.1
Morris, R.E.2
-
58
-
-
0032105481
-
Rapamune (RAPA, rapamycin, sirolimus): Mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression
-
Sehgal, S. N. 1998. Rapamune (RAPA, rapamycin, sirolimus): mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression. Clin. Biochem. 31:335.
-
(1998)
Clin. Biochem.
, vol.31
, pp. 335
-
-
Sehgal, S.N.1
-
60
-
-
0031833563
-
Mammalian target of rapamycin: Immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling
-
Abraham, R. T. 1998. Mammalian target of rapamycin: immunosuppressive drugs uncover a novel pathway of cytokine receptor signaling. Curr. Opin. Immunol. 10:330.
-
(1998)
Curr. Opin. Immunol.
, vol.10
, pp. 330
-
-
Abraham, R.T.1
-
61
-
-
0023686772
-
Negative regulation by glucocorticoids through interference with a cAMP responsive enhancer
-
Akerblom, I. E., E. P. Slater, M. Beato, J. D. Baxter, and P. L. Mellon. 1988. Negative regulation by glucocorticoids through interference with a cAMP responsive enhancer. Science 241:350.
-
(1988)
Science
, vol.241
, pp. 350
-
-
Akerblom, I.E.1
Slater, E.P.2
Beato, M.3
Baxter, J.D.4
Mellon, P.L.5
-
62
-
-
0028867899
-
Immunosuppression by glucocorticoids: Inhibition of NF-κB activity through induction of IκB synthesis
-
Auphan, N., J. A. DiDonato, C. Rosette, A. Helmberg, and M. Karin. 1995. Immunosuppression by glucocorticoids: inhibition of NF-κB activity through induction of IκB synthesis. Science 270:286.
-
(1995)
Science
, vol.270
, pp. 286
-
-
Auphan, N.1
DiDonato, J.A.2
Rosette, C.3
Helmberg, A.4
Karin, M.5
-
63
-
-
0028831128
-
Characterization of mechanisms involved in transrepression of NF-κB by activated glucocorticoid receptors
-
Scheinman, R. I., A. Gualberto, C. M. Jewell, J. A. Cidlowski, and A. S. Baldwin. Jr. 1995. Characterization of mechanisms involved in transrepression of NF-κB by activated glucocorticoid receptors. Mol. Cell. Biol. 15:943.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 943
-
-
Scheinman, R.I.1
Gualberto, A.2
Jewell, C.M.3
Cidlowski, J.A.4
Baldwin A.S., Jr.5
|