Thrombocytopenia in early malaria is associated with GP1b shedding in absence of systemic platelet activation and consumptive coagulopathy

British Journal of Haematology

Volumn 151, Issue 5, 2010, Pages 495-503

  De Mast, Quirijn ^a   De Groot, Philip G ^b   Van Heerde, Waander L ^a   Roestenberg, Meta ^a   Van Velzen, Jeroen F ^a   Verbruggen, Bert ^a   Roest, Mark ^b   McCall, Matthew ^a   Nieman, An Emmie ^a   Westendorp, Josien ^a   Syafruddin, Din ^c   Fijnheer, Rob ^b   Van Dongen Lases, Edmee C ^a   Sauerwein, Robert W ^a   Van Der Ven, Andre J ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^c EIJKMAN INSTITUTE FOR MOLECULAR BIOLOGY   (Indonesia)

Author keywords

Glycoprotein 1b; Malaria; Platelet activation; Platelets; Thrombocytopenia; Von Willebrand factor

Indexed keywords

ARTEMETHER PLUS BENFLUMETOL; CD40 LIGAND; CD63 ANTIGEN; CHEMOKINE; CHEMOKINE RECEPTOR CXCR4; CXCL7 CHEMOKINE; D DIMER; DUAL SPECIFICITY PHOSPHATASE 2; FIBRINOGEN; GLYCOPROTEIN IB; PADGEM PROTEIN; RANTES; THROMBOPOIETIN; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

ARTICLE; BLOOD CLOTTING DISORDER; CLINICAL ARTICLE; DISEASE ASSOCIATION; DISSEMINATED INTRAVASCULAR CLOTTING; EX VIVO STUDY; FLOW CYTOMETRY; HUMAN; IN VITRO STUDY; MALARIA FALCIPARUM; NONHUMAN; PARTIAL THROMBOPLASTIN TIME; PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX MALARIA; PRIORITY JOURNAL; THROMBOCYTE ACTIVATION; THROMBOCYTOPENIA;

DISSEMINATED INTRAVASCULAR COAGULATION; HUMANS; MALARIA, FALCIPARUM; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET FUNCTION TESTS; PLATELET GLYCOPROTEIN GPIB-IX COMPLEX; THROMBOCYTOPENIA; VON WILLEBRAND FACTOR;

EID: 78349237750     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2010.08399.x     Document Type: Article

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