A mitochondria-targeted nitroxide is reduced to its hydroxylamine by ubiquinol in mitochondria

Free Radical Biology and Medicine

Volumn 44, Issue 7, 2008, Pages 1406-1419

  Trnka, Jan ^a   Blaikie, Frances H ^b   Smith, Robin A J ^b   Murphy, Michael P ^a  

^a WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^b UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

Mitochondria targeting; Nitroxide; TEMPOL; Triphenylphosphonium; Ubiquinol

Indexed keywords

HYDROGEN; HYDROXYLAMINE; NITROXIDE; ORGANIC SOLVENT; PHOSPHONIUM DERIVATIVE; PIPERIDINE DERIVATIVE; UBIQUINOL CYTOCHROME C REDUCTASE; UBIQUINONE;

ANTIOXIDANT ACTIVITY; ARTICLE; CELL MEMBRANE; IN VIVO STUDY; LIPOPHILICITY; MITOCHONDRIAL ENERGY TRANSFER; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PRIORITY JOURNAL; PROTON TRANSPORT; REACTION ANALYSIS;

ANTIOXIDANTS; BIOCHEMISTRY; CATIONS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYCLIC N-OXIDES; ELECTRON SPIN RESONANCE SPECTROSCOPY; HYDROXYLAMINE; MASS SPECTROMETRY; MITOCHONDRIA; MODELS, CHEMICAL; NITRIC OXIDE; OXIDATIVE STRESS; SPIN LABELS; SUPEROXIDES; TIME FACTORS; UBIQUINONE;

EID: 40949161089     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2007.12.036     Document Type: Article

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