-
2
-
-
84879077265
-
Alzheimer disease in the United States (2010-2050) estimated using the 2010 census
-
L.E. Hebert, J. Weuve, P.A. Scherr, and D.A. Evans Alzheimer disease in the United States (2010-2050) estimated using the 2010 census Neurology 80 2013 1778 1783
-
(2013)
Neurology
, vol.80
, pp. 1778-1783
-
-
Hebert, L.E.1
Weuve, J.2
Scherr, P.A.3
Evans, D.A.4
-
3
-
-
84880186196
-
Segregation of a missense mutation in the amyloid beta-protein precursor gene with familial Alzheimer's disease
-
A. Goate Segregation of a missense mutation in the amyloid beta-protein precursor gene with familial Alzheimer's disease J Alzheimers Dis 9 suppl 3 2006 341 347
-
(2006)
J Alzheimers Dis
, vol.9
, Issue.SUPPL. 3
, pp. 341-347
-
-
Goate, A.1
-
4
-
-
0026088977
-
Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease
-
A. Goate, M.C. Chartier-Harlin, M. Mullan, J. Brown, F. Crawford, and L. Fidani et al. Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease Nature 349 1991 704 706
-
(1991)
Nature
, vol.349
, pp. 704-706
-
-
Goate, A.1
Chartier-Harlin, M.C.2
Mullan, M.3
Brown, J.4
Crawford, F.5
Fidani, L.6
-
5
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
R. Sherrington, E.I. Rogaev, Y. Liang, E.A. Rogaeva, G. Levesque, and M. Ikeda et al. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease Nature 375 1995 754 760
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
-
6
-
-
0029087026
-
Candidate gene for the chromosome 1 familial Alzheimer's disease locus
-
E. Levy-Lahad, W. Wasco, P. Poorkaj, D.M. Romano, J. Oshima, and W.H. Pettingell et al. Candidate gene for the chromosome 1 familial Alzheimer's disease locus Science 269 1995 973 977
-
(1995)
Science
, vol.269
, pp. 973-977
-
-
Levy-Lahad, E.1
Wasco, W.2
Poorkaj, P.3
Romano, D.M.4
Oshima, J.5
Pettingell, W.H.6
-
7
-
-
0031839545
-
Risk estimates of dementia by apolipoprotein e genotypes from a population-based incidence study: The Rotterdam Study
-
A.J. Slooter, M. Cruts, S. Kalmijn, A. Hofman, M.M. Breteler, and C. Van Broeckhoven et al. Risk estimates of dementia by apolipoprotein E genotypes from a population-based incidence study: The Rotterdam Study Arch Neurol 55 1998 964 968
-
(1998)
Arch Neurol
, vol.55
, pp. 964-968
-
-
Slooter, A.J.1
Cruts, M.2
Kalmijn, S.3
Hofman, A.4
Breteler, M.M.5
Van Broeckhoven, C.6
-
8
-
-
0030823158
-
Effects of age, sex, and ethnicity on the association between apolipoprotein e genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium
-
L.A. Farrer, L.A. Cupples, J.L. Haines, B. Hyman, W.A. Kukull, and R. Mayeux et al. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium JAMA 278 1997 1349 1356
-
(1997)
JAMA
, vol.278
, pp. 1349-1356
-
-
Farrer, L.A.1
Cupples, L.A.2
Haines, J.L.3
Hyman, B.4
Kukull, W.A.5
Mayeux, R.6
-
9
-
-
83455230813
-
Prevalence of apolipoprotein E4 genotype and homozygotes (APOE e4/4) among patients diagnosed with Alzheimer's disease: A systematic review and meta-analysis
-
A. Ward, S. Crean, C.J. Mercaldi, J.M. Collins, D. Boyd, and M.N. Cook et al. Prevalence of apolipoprotein E4 genotype and homozygotes (APOE e4/4) among patients diagnosed with Alzheimer's disease: A systematic review and meta-analysis Neuroepidemiology 38 2012 1 17
-
(2012)
Neuroepidemiology
, vol.38
, pp. 1-17
-
-
Ward, A.1
Crean, S.2
Mercaldi, C.J.3
Collins, J.M.4
Boyd, D.5
Cook, M.N.6
-
10
-
-
78549264026
-
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
-
J.C. Lambert, S. Heath, G. Even, D. Campion, K. Sleegers, and M. Hiltunen et al. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease Nat Genet 41 2009 1094 1099
-
(2009)
Nat Genet
, vol.41
, pp. 1094-1099
-
-
Lambert, J.C.1
Heath, S.2
Even, G.3
Campion, D.4
Sleegers, K.5
Hiltunen, M.6
-
11
-
-
79955484414
-
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
-
P. Hollingworth, D. Harold, R. Sims, A. Gerrish, J.C. Lambert, and M.M. Carrasquillo et al. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease Nat Genet 43 2011 429 435
-
(2011)
Nat Genet
, vol.43
, pp. 429-435
-
-
Hollingworth, P.1
Harold, D.2
Sims, R.3
Gerrish, A.4
Lambert, J.C.5
Carrasquillo, M.M.6
-
12
-
-
77952307991
-
Genome-wide analysis of genetic loci associated with Alzheimer disease
-
S. Seshadri, A.L. Fitzpatrick, M.A. Ikram, A.L. DeStefano, V. Gudnason, and M. Boada et al. Genome-wide analysis of genetic loci associated with Alzheimer disease JAMA 303 2010 1832 1840
-
(2010)
JAMA
, vol.303
, pp. 1832-1840
-
-
Seshadri, S.1
Fitzpatrick, A.L.2
Ikram, M.A.3
Destefano, A.L.4
Gudnason, V.5
Boada, M.6
-
13
-
-
79955464911
-
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
-
A.C. Naj, G. Jun, G.W. Beecham, L.S. Wang, B.N. Vardarajan, and J. Buros et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease Nat Genet 43 2011 436 441
-
(2011)
Nat Genet
, vol.43
, pp. 436-441
-
-
Naj, A.C.1
Jun, G.2
Beecham, G.W.3
Wang, L.S.4
Vardarajan, B.N.5
Buros, J.6
-
14
-
-
79551474326
-
SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk
-
C. Reitz, S. Tokuhiro, L.N. Clark, C. Conrad, J.P. Vonsattel, and L.N. Hazrati et al. SORCS1 alters amyloid precursor protein processing and variants may increase Alzheimer's disease risk Ann Neurol 69 2011 47 64
-
(2011)
Ann Neurol
, vol.69
, pp. 47-64
-
-
Reitz, C.1
Tokuhiro, S.2
Clark, L.N.3
Conrad, C.4
Vonsattel, J.P.5
Hazrati, L.N.6
-
15
-
-
84872057940
-
TREM2 variants in Alzheimer's disease
-
R. Guerreiro, A. Wojtas, J. Bras, M. Carrasquillo, E. Rogaeva, and E. Majounie et al. TREM2 variants in Alzheimer's disease N Engl J Med 368 2013 117 127
-
(2013)
N Engl J Med
, vol.368
, pp. 117-127
-
-
Guerreiro, R.1
Wojtas, A.2
Bras, J.3
Carrasquillo, M.4
Rogaeva, E.5
Majounie, E.6
-
16
-
-
84872088087
-
Variant of TREM2 associated with the risk of Alzheimer's disease
-
T. Jonsson, H. Stefansson, S. Steinberg, I. Jonsdottir, P.V. Jonsson, and J. Snaedal et al. Variant of TREM2 associated with the risk of Alzheimer's disease N Engl J Med 368 2013 107 116
-
(2013)
N Engl J Med
, vol.368
, pp. 107-116
-
-
Jonsson, T.1
Stefansson, H.2
Steinberg, S.3
Jonsdottir, I.4
Jonsson, P.V.5
Snaedal, J.6
-
17
-
-
18844479720
-
Heritability for Alzheimer's disease: The study of dementia in Swedish twins
-
M. Gatz, N.L. Pedersen, S. Berg, B. Johansson, K. Johansson, and J.A. Mortimer et al. Heritability for Alzheimer's disease: The study of dementia in Swedish twins J Gerontol A Biol Sci Med Sci 52 1997 M117 M125
-
(1997)
J Gerontol A Biol Sci Med Sci
, vol.52
-
-
Gatz, M.1
Pedersen, N.L.2
Berg, S.3
Johansson, B.4
Johansson, K.5
Mortimer, J.A.6
-
18
-
-
0037318496
-
Incidence of Alzheimer disease in a biracial urban community: Relation to apolipoprotein e allele status
-
D.A. Evans, D.A. Bennett, R.S. Wilson, J.L. Bienias, M.C. Morris, and P.A. Scherr et al. Incidence of Alzheimer disease in a biracial urban community: Relation to apolipoprotein E allele status Arch Neurol 60 2003 185 189
-
(2003)
Arch Neurol
, vol.60
, pp. 185-189
-
-
Evans, D.A.1
Bennett, D.A.2
Wilson, R.S.3
Bienias, J.L.4
Morris, M.C.5
Scherr, P.A.6
-
19
-
-
0036219565
-
Association between apolipoprotein e genotype and Alzheimer disease in African American subjects
-
N.R. Graff-Radford, R.C. Green, R.C. Go, M.L. Hutton, T. Edeki, and D. Bachman et al. Association between apolipoprotein E genotype and Alzheimer disease in African American subjects Arch Neurol 59 2002 594 600
-
(2002)
Arch Neurol
, vol.59
, pp. 594-600
-
-
Graff-Radford, N.R.1
Green, R.C.2
Go, R.C.3
Hutton, M.L.4
Edeki, T.5
Bachman, D.6
-
20
-
-
33644917156
-
Association of apolipoprotein e genotype and Alzheimer disease in African Americans
-
J.R. Murrell, B. Price, K.A. Lane, O. Baiyewu, O. Gureje, and A. Ogunniyi et al. Association of apolipoprotein E genotype and Alzheimer disease in African Americans Arch Neurol 63 2006 431 434
-
(2006)
Arch Neurol
, vol.63
, pp. 431-434
-
-
Murrell, J.R.1
Price, B.2
Lane, K.A.3
Baiyewu, O.4
Gureje, O.5
Ogunniyi, A.6
-
21
-
-
0035830436
-
Incidence of AD in African-Americans, Caribbean Hispanics, and Caucasians in northern Manhattan
-
M.X. Tang, P. Cross, H. Andrews, D.M. Jacobs, S. Small, and K. Bell et al. Incidence of AD in African-Americans, Caribbean Hispanics, and Caucasians in northern Manhattan Neurology 56 2001 49 56
-
(2001)
Neurology
, vol.56
, pp. 49-56
-
-
Tang, M.X.1
Cross, P.2
Andrews, H.3
Jacobs, D.M.4
Small, S.5
Bell, K.6
-
22
-
-
0032507032
-
The APOE-epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics
-
M.X. Tang, Y. Stern, K. Marder, K. Bell, B. Gurland, and R. Lantigua et al. The APOE-epsilon4 allele and the risk of Alzheimer disease among African Americans, whites, and Hispanics JAMA 279 1998 751 755
-
(1998)
JAMA
, vol.279
, pp. 751-755
-
-
Tang, M.X.1
Stern, Y.2
Marder, K.3
Bell, K.4
Gurland, B.5
Lantigua, R.6
-
23
-
-
84858225391
-
-
(2012): 2012 Alzheimer's disease facts and figures
-
(2012): 2012 Alzheimer's disease facts and figures Alzheimers Dement 8 2012 131 168
-
(2012)
Alzheimers Dement
, vol.8
, pp. 131-168
-
-
-
24
-
-
0037116658
-
Risk of dementia among white and African American relatives of patients with Alzheimer disease
-
R.C. Green, L.A. Cupples, R. Go, K.S. Benke, T. Edeki, and P.A. Griffith et al. Risk of dementia among white and African American relatives of patients with Alzheimer disease JAMA 287 2002 329 336
-
(2002)
JAMA
, vol.287
, pp. 329-336
-
-
Green, R.C.1
Cupples, L.A.2
Go, R.3
Benke, K.S.4
Edeki, T.5
Griffith, P.A.6
-
25
-
-
0033595026
-
APOE-epsilon4 count predicts age when prevalence of AD increases, then declines: The Cache County Study
-
J.C. Breitner, B.W. Wyse, J.C. Anthony, K.A. Welsh-Bohmer, D.C. Steffens, and M.C. Norton et al. APOE-epsilon4 count predicts age when prevalence of AD increases, then declines: the Cache County Study Neurology 53 1999 321 331
-
(1999)
Neurology
, vol.53
, pp. 321-331
-
-
Breitner, J.C.1
Wyse, B.W.2
Anthony, J.C.3
Welsh-Bohmer, K.A.4
Steffens, D.C.5
Norton, M.C.6
-
26
-
-
0027194791
-
Gene dose of apolipoprotein e type 4 allele and the risk of Alzheimer's disease in late onset families
-
E.H. Corder, A.M. Saunders, W.J. Strittmatter, D.E. Schmechel, P.C. Gaskell, and G.W. Small et al. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families Science 261 1993 921 923
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
-
27
-
-
0030050286
-
Clinical and pathological correlates of apolipoprotein e epsilon 4 in Alzheimer's disease
-
T. Gomez-Isla, H.L. West, G.W. Rebeck, S.D. Harr, J.H. Growdon, and J.J. Locascio et al. Clinical and pathological correlates of apolipoprotein E epsilon 4 in Alzheimer's disease Ann Neurol 39 1996 62 70
-
(1996)
Ann Neurol
, vol.39
, pp. 62-70
-
-
Gomez-Isla, T.1
West, H.L.2
Rebeck, G.W.3
Harr, S.D.4
Growdon, J.H.5
Locascio, J.J.6
-
28
-
-
0030462762
-
Apolipoprotein E: Non-cognitive symptoms and cognitive decline in late onset Alzheimer's disease
-
C. Holmes, R. Levy, D.M. McLoughlin, J.F. Powell, and S. Lovestone Apolipoprotein E: non-cognitive symptoms and cognitive decline in late onset Alzheimer's disease J Neurol Neurosurg Psychiatry 61 1996 580 583
-
(1996)
J Neurol Neurosurg Psychiatry
, vol.61
, pp. 580-583
-
-
Holmes, C.1
Levy, R.2
McLoughlin, D.M.3
Powell, J.F.4
Lovestone, S.5
-
29
-
-
8044230698
-
Epidemiological, clinical, and neuropathological study of apolipoprotein e genotype in Alzheimer's disease
-
B.T. Hyman, T. Gomez-Isla, G.W. Rebeck, M. Briggs, H. Chung, and H.L. West et al. Epidemiological, clinical, and neuropathological study of apolipoprotein E genotype in Alzheimer's disease Ann N Y Acad Sci 802 1996 1 5
-
(1996)
Ann N y Acad Sci
, vol.802
, pp. 1-5
-
-
Hyman, B.T.1
Gomez-Isla, T.2
Rebeck, G.W.3
Briggs, M.4
Chung, H.5
West, H.L.6
-
30
-
-
0029893288
-
Apolipoprotein e type 4 allele and Alzheimer's disease: Effect on age at onset and relative risk in different age groups
-
A. Kurz, K. Altland, N. Lautenschlager, R. Zimmer, R. Busch, and I. Gerundt et al. Apolipoprotein E type 4 allele and Alzheimer's disease: Effect on age at onset and relative risk in different age groups J Neurol 243 1996 452 456
-
(1996)
J Neurol
, vol.243
, pp. 452-456
-
-
Kurz, A.1
Altland, K.2
Lautenschlager, N.3
Zimmer, R.4
Busch, R.5
Gerundt, I.6
-
31
-
-
0029781636
-
Apolipoprotein e and Alzheimer's disease: Strength of association is related to age at onset
-
D.L. Murman, N.L. Foster, S.P. Kilgore, C.A. McDonagh, and J.K. Fink Apolipoprotein E and Alzheimer's disease: Strength of association is related to age at onset Dementia 7 1996 251 255
-
(1996)
Dementia
, vol.7
, pp. 251-255
-
-
Murman, D.L.1
Foster, N.L.2
Kilgore, S.P.3
McDonagh, C.A.4
Fink, J.K.5
-
32
-
-
0027282035
-
Apolipoprotein e polymorphism and Alzheimer's disease
-
J. Poirier, J. Davignon, D. Bouthillier, S. Kogan, P. Bertrand, and S. Gauthier Apolipoprotein E polymorphism and Alzheimer's disease Lancet 342 1993 697 699
-
(1993)
Lancet
, vol.342
, pp. 697-699
-
-
Poirier, J.1
Davignon, J.2
Bouthillier, D.3
Kogan, S.4
Bertrand, P.5
Gauthier, S.6
-
33
-
-
0030747771
-
Alzheimer's disease: The genetics of risk
-
51-55, 58-63, 67-59
-
A.D. Roses Alzheimer's disease: the genetics of risk Hosp Pract (Minneap) 32 1997 51-55, 58-63, 67-59
-
(1997)
Hosp Pract (Minneap)
, vol.32
-
-
Roses, A.D.1
-
34
-
-
19144373595
-
Relative risk of Alzheimer disease and age-at-onset distributions, based on APOE genotypes among elderly African Americans, Caucasians, and Hispanics in New York City
-
M.X. Tang, G. Maestre, W.Y. Tsai, X.H. Liu, L. Feng, and W.Y. Chung et al. Relative risk of Alzheimer disease and age-at-onset distributions, based on APOE genotypes among elderly African Americans, Caucasians, and Hispanics in New York City Am J Hum Genet 58 1996 574 584
-
(1996)
Am J Hum Genet
, vol.58
, pp. 574-584
-
-
Tang, M.X.1
Maestre, G.2
Tsai, W.Y.3
Liu, X.H.4
Feng, L.5
Chung, W.Y.6
-
35
-
-
0036592518
-
Non-familial Alzheimer's disease is mainly due to genetic factors
-
J.W. Ashford, and J.A. Mortimer Non-familial Alzheimer's disease is mainly due to genetic factors J Alzheimers Dis 4 2002 169 177
-
(2002)
J Alzheimers Dis
, vol.4
, pp. 169-177
-
-
Ashford, J.W.1
Mortimer, J.A.2
-
36
-
-
12044254746
-
Binding of human apolipoprotein e to synthetic amyloid beta peptide: Isoform-specific effects and implications for late-onset Alzheimer disease
-
W.J. Strittmatter, K.H. Weisgraber, D.Y. Huang, L.M. Dong, G.S. Salvesen, and M. Pericak-Vance et al. Binding of human apolipoprotein E to synthetic amyloid beta peptide: Isoform-specific effects and implications for late-onset Alzheimer disease Proc Natl Acad Sci U S A 90 1993 8098 8102
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 8098-8102
-
-
Strittmatter, W.J.1
Weisgraber, K.H.2
Huang, D.Y.3
Dong, L.M.4
Salvesen, G.S.5
Pericak-Vance, M.6
-
37
-
-
0027365822
-
Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein e genotype in late-onset Alzheimer disease
-
D.E. Schmechel, A.M. Saunders, W.J. Strittmatter, B.J. Crain, C.M. Hulette, and S.H. Joo et al. Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease Proc Natl Acad Sci U S A 90 1993 9649 9653
-
(1993)
Proc Natl Acad Sci U S A
, vol.90
, pp. 9649-9653
-
-
Schmechel, D.E.1
Saunders, A.M.2
Strittmatter, W.J.3
Crain, B.J.4
Hulette, C.M.5
Joo, S.H.6
-
38
-
-
0027374047
-
Apolipoprotein e in sporadic Alzheimer's disease: Allelic variation and receptor interactions
-
G.W. Rebeck, J.S. Reiter, D.K. Strickland, and B.T. Hyman Apolipoprotein E in sporadic Alzheimer's disease: Allelic variation and receptor interactions Neuron 11 1993 575 580
-
(1993)
Neuron
, vol.11
, pp. 575-580
-
-
Rebeck, G.W.1
Reiter, J.S.2
Strickland, D.K.3
Hyman, B.T.4
-
39
-
-
0033593027
-
Apolipoprotein e is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease
-
K.R. Bales, T. Verina, D.J. Cummins, Y. Du, R.C. Dodel, and J. Saura et al. Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease Proc Natl Acad Sci U S A 96 1999 15233 15238
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 15233-15238
-
-
Bales, K.R.1
Verina, T.2
Cummins, D.J.3
Du, Y.4
Dodel, R.C.5
Saura, J.6
-
40
-
-
0031278270
-
Lack of apolipoprotein e dramatically reduces amyloid beta-peptide deposition
-
K.R. Bales, T. Verina, R.C. Dodel, Y. Du, L. Altstiel, and M. Bender et al. Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition Nat Genet 17 1997 263 264
-
(1997)
Nat Genet
, vol.17
, pp. 263-264
-
-
Bales, K.R.1
Verina, T.2
Dodel, R.C.3
Du, Y.4
Altstiel, L.5
Bender, M.6
-
41
-
-
0031899218
-
Reduction in amyloid A amyloid formation in apolipoprotein-E-deficient mice
-
M.S. Kindy, and D.J. Rader Reduction in amyloid A amyloid formation in apolipoprotein-E-deficient mice Am J Pathol 152 1998 1387 1395
-
(1998)
Am J Pathol
, vol.152
, pp. 1387-1395
-
-
Kindy, M.S.1
Rader, D.J.2
-
42
-
-
0028173205
-
Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein e promote assembly of Alzheimer beta-protein into filaments
-
J. Ma, A. Yee, H.B. Brewer Jr, S. Das, and H. Potter Amyloid-associated proteins alpha 1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer beta-protein into filaments Nature 372 1994 92 94
-
(1994)
Nature
, vol.372
, pp. 92-94
-
-
Ma, J.1
Yee, A.2
Brewer, Jr.H.B.3
Das, S.4
Potter, H.5
-
43
-
-
0028026587
-
Apolipoprotein e associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3
-
D.A. Sanan, K.H. Weisgraber, S.J. Russell, R.W. Mahley, D. Huang, and A. Saunders et al. Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3 J Clin Invest 94 1994 860 869
-
(1994)
J Clin Invest
, vol.94
, pp. 860-869
-
-
Sanan, D.A.1
Weisgraber, K.H.2
Russell, S.J.3
Mahley, R.W.4
Huang, D.5
Saunders, A.6
-
44
-
-
4243215848
-
Apolipoprotein e isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease
-
D.M. Holtzman, K.R. Bales, T. Tenkova, A.M. Fagan, M. Parsadanian, and L.J. Sartorius et al. Apolipoprotein E isoform-dependent amyloid deposition and neuritic degeneration in a mouse model of Alzheimer's disease Proc Natl Acad Sci U S A 97 2000 2892 2897
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 2892-2897
-
-
Holtzman, D.M.1
Bales, K.R.2
Tenkova, T.3
Fagan, A.M.4
Parsadanian, M.5
Sartorius, L.J.6
-
45
-
-
0033559412
-
Expression of human apolipoprotein e reduces amyloid-beta deposition in a mouse model of Alzheimer's disease
-
D.M. Holtzman, K.R. Bales, S. Wu, P. Bhat, M. Parsadanian, and A.M. Fagan et al. Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease J Clin Invest 103 1999 R15 R21
-
(1999)
J Clin Invest
, vol.103
-
-
Holtzman, D.M.1
Bales, K.R.2
Wu, S.3
Bhat, P.4
Parsadanian, M.5
Fagan, A.M.6
-
46
-
-
0028177562
-
Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol
-
D.L. Sparks, S.W. Scheff, J.C. Hunsaker 3rd, H. Liu, T. Landers, and D.R. Gross Induction of Alzheimer-like beta-amyloid immunoreactivity in the brains of rabbits with dietary cholesterol Exp Neurol 126 1994 88 94
-
(1994)
Exp Neurol
, vol.126
, pp. 88-94
-
-
Sparks, D.L.1
Scheff, S.W.2
Hunsaker III, J.C.3
Liu, H.4
Landers, T.5
Gross, D.R.6
-
47
-
-
0033833354
-
Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model
-
L.M. Refolo, B. Malester, J. LaFrancois, T. Bryant-Thomas, R. Wang, and G.S. Tint et al. Hypercholesterolemia accelerates the Alzheimer's amyloid pathology in a transgenic mouse model Neurobiol Dis 7 2000 321 331
-
(2000)
Neurobiol Dis
, vol.7
, pp. 321-331
-
-
Refolo, L.M.1
Malester, B.2
Lafrancois, J.3
Bryant-Thomas, T.4
Wang, R.5
Tint, G.S.6
-
48
-
-
0029671454
-
Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein
-
S. Bodovitz, and W.L. Klein Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein J Biol Chem 271 1996 4436 4440
-
(1996)
J Biol Chem
, vol.271
, pp. 4436-4440
-
-
Bodovitz, S.1
Klein, W.L.2
-
49
-
-
0032568843
-
Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol
-
D.S. Howland, S.P. Trusko, M.J. Savage, A.G. Reaume, D.M. Lang, and J.D. Hirsch et al. Modulation of secreted beta-amyloid precursor protein and amyloid beta-peptide in brain by cholesterol J Biol Chem 273 1998 16576 16582
-
(1998)
J Biol Chem
, vol.273
, pp. 16576-16582
-
-
Howland, D.S.1
Trusko, S.P.2
Savage, M.J.3
Reaume, A.G.4
Lang, D.M.5
Hirsch, J.D.6
-
50
-
-
4444229063
-
APOE and APOC1 promoter polymorphisms and the risk of Alzheimer disease in African American and Caribbean Hispanic individuals
-
B. Tycko, J.H. Lee, A. Ciappa, A. Saxena, C.M. Li, and L. Feng et al. APOE and APOC1 promoter polymorphisms and the risk of Alzheimer disease in African American and Caribbean Hispanic individuals Arch Neurol 61 2004 1434 1439
-
(2004)
Arch Neurol
, vol.61
, pp. 1434-1439
-
-
Tycko, B.1
Lee, J.H.2
Ciappa, A.3
Saxena, A.4
Li, C.M.5
Feng, L.6
-
51
-
-
84875922261
-
Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein e 4,and the risk of late-onset Alzheimer disease in African Americans
-
C. Reitz, G. Jun, A. Naj, R. Rajbhandary, B.N. Vardarajan, and L.S. Wang et al. Variants in the ATP-binding cassette transporter (ABCA7), apolipoprotein E 4,and the risk of late-onset Alzheimer disease in African Americans JAMA 309 2013 1483 1492
-
(2013)
JAMA
, vol.309
, pp. 1483-1492
-
-
Reitz, C.1
Jun, G.2
Naj, A.3
Rajbhandary, R.4
Vardarajan, B.N.5
Wang, L.S.6
-
52
-
-
77957138140
-
A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease
-
A.D. Roses, M.W. Lutz, H. Amrine-Madsen, A.M. Saunders, D.G. Crenshaw, and S.S. Sundseth et al. A TOMM40 variable-length polymorphism predicts the age of late-onset Alzheimer's disease Pharmacogenomics J 10 2010 375 384
-
(2010)
Pharmacogenomics J
, vol.10
, pp. 375-384
-
-
Roses, A.D.1
Lutz, M.W.2
Amrine-Madsen, H.3
Saunders, A.M.4
Crenshaw, D.G.5
Sundseth, S.S.6
-
53
-
-
80051564625
-
Association and expression analyses with single-nucleotide polymorphisms in TOMM40 in Alzheimer disease
-
C. Cruchaga, P. Nowotny, J.S. Kauwe, P.G. Ridge, K. Mayo, and S. Bertelsen et al. Association and expression analyses with single-nucleotide polymorphisms in TOMM40 in Alzheimer disease Arch Neurol 68 2011 1013 1019
-
(2011)
Arch Neurol
, vol.68
, pp. 1013-1019
-
-
Cruchaga, C.1
Nowotny, P.2
Kauwe, J.S.3
Ridge, P.G.4
Mayo, K.5
Bertelsen, S.6
-
54
-
-
84867339613
-
Comprehensive search for Alzheimer disease susceptibility loci in the APOE region
-
G. Jun, B.N. Vardarajan, J. Buros, C.E. Yu, M.V. Hawk, and B.A. Dombroski et al. Comprehensive search for Alzheimer disease susceptibility loci in the APOE region Arch Neurol 69 2012 1270 1279
-
(2012)
Arch Neurol
, vol.69
, pp. 1270-1279
-
-
Jun, G.1
Vardarajan, B.N.2
Buros, J.3
Yu, C.E.4
Hawk, M.V.5
Dombroski, B.A.6
-
55
-
-
0030770726
-
Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12
-
M.A. Pericak-Vance, M.P. Bass, L.H. Yamaoka, P.C. Gaskell, W.K. Scott, and H.A. Terwedow et al. Complete genomic screen in late-onset familial Alzheimer disease. Evidence for a new locus on chromosome 12 JAMA 278 1997 1237 1241
-
(1997)
JAMA
, vol.278
, pp. 1237-1241
-
-
Pericak-Vance, M.A.1
Bass, M.P.2
Yamaoka, L.H.3
Gaskell, P.C.4
Scott, W.K.5
Terwedow, H.A.6
-
56
-
-
0032547369
-
Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity
-
E. Rogaeva, S. Premkumar, Y. Song, S. Sorbi, N. Brindle, and A. Paterson et al. Evidence for an Alzheimer disease susceptibility locus on chromosome 12 and for further locus heterogeneity JAMA 280 1998 614 618
-
(1998)
JAMA
, vol.280
, pp. 614-618
-
-
Rogaeva, E.1
Premkumar, S.2
Song, Y.3
Sorbi, S.4
Brindle, N.5
Paterson, A.6
-
57
-
-
0033913161
-
Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: Potential genetic and phenotypic heterogeneity
-
W.K. Scott, J.M. Grubber, P.M. Conneally, G.W. Small, C.M. Hulette, and C.K. Rosenberg et al. Fine mapping of the chromosome 12 late-onset Alzheimer disease locus: Potential genetic and phenotypic heterogeneity Am J Hum Genet 66 2000 922 932
-
(2000)
Am J Hum Genet
, vol.66
, pp. 922-932
-
-
Scott, W.K.1
Grubber, J.M.2
Conneally, P.M.3
Small, G.W.4
Hulette, C.M.5
Rosenberg, C.K.6
-
58
-
-
0033540726
-
Further evidence linking late-onset Alzheimer disease with chromosome 12
-
W.K. Scott, J.M. Grubber, S.M. Abou-Donia, T.D. Church, A.M. Saunders, and A.D. Roses et al. Further evidence linking late-onset Alzheimer disease with chromosome 12 JAMA 281 1999 513 514
-
(1999)
JAMA
, vol.281
, pp. 513-514
-
-
Scott, W.K.1
Grubber, J.M.2
Abou-Donia, S.M.3
Church, T.D.4
Saunders, A.M.5
Roses, A.D.6
-
59
-
-
18244384759
-
Chromosome-12 mapping of late-onset Alzheimer disease among Caribbean Hispanics
-
R. Mayeux, J.H. Lee, S.N. Romas, D. Mayo, V. Santana, and J. Williamson et al. Chromosome-12 mapping of late-onset Alzheimer disease among Caribbean Hispanics Am J Hum Genet 70 2002 237 243
-
(2002)
Am J Hum Genet
, vol.70
, pp. 237-243
-
-
Mayeux, R.1
Lee, J.H.2
Romas, S.N.3
Mayo, D.4
Santana, V.5
Williamson, J.6
-
60
-
-
4444253260
-
Fine mapping of 10q and 18q for familial Alzheimer's disease in Caribbean Hispanics
-
J.H. Lee, R. Mayeux, D. Mayo, J. Mo, V. Santana, and J. Williamson et al. Fine mapping of 10q and 18q for familial Alzheimer's disease in Caribbean Hispanics Mol Psychiatry 9 2004 1042 1051
-
(2004)
Mol Psychiatry
, vol.9
, pp. 1042-1051
-
-
Lee, J.H.1
Mayeux, R.2
Mayo, D.3
Mo, J.4
Santana, V.5
Williamson, J.6
-
61
-
-
42149162175
-
Further examination of the candidate genes in chromosome 12p13 locus for late-onset Alzheimer disease
-
J.H. Lee, R. Cheng, E. Rogaeva, Y. Meng, Y. Stern, and V. Santana et al. Further examination of the candidate genes in chromosome 12p13 locus for late-onset Alzheimer disease Neurogenetics 9 2008 127 138
-
(2008)
Neurogenetics
, vol.9
, pp. 127-138
-
-
Lee, J.H.1
Cheng, R.2
Rogaeva, E.3
Meng, Y.4
Stern, Y.5
Santana, V.6
-
62
-
-
33750977267
-
Expanded genomewide scan implicates a novel locus at 3q28 among Caribbean hispanics with familial Alzheimer disease
-
J.H. Lee, R. Cheng, V. Santana, J. Williamson, R. Lantigua, and M. Medrano et al. Expanded genomewide scan implicates a novel locus at 3q28 among Caribbean hispanics with familial Alzheimer disease Arch Neurol 63 2006 1591 1598
-
(2006)
Arch Neurol
, vol.63
, pp. 1591-1598
-
-
Lee, J.H.1
Cheng, R.2
Santana, V.3
Williamson, J.4
Lantigua, R.5
Medrano, M.6
-
63
-
-
32244436670
-
A genome-wide linkage analysis of dementia in the Amish
-
D.W. Hahs, J.L. McCauley, A.E. Crunk, L.L. McFarland, P.C. Gaskell, and L. Jiang et al. A genome-wide linkage analysis of dementia in the Amish Am J Med Genet B Neuropsychiatr Genet 141B 2006 160 166
-
(2006)
Am J Med Genet B Neuropsychiatr Genet
, vol.141 B
, pp. 160-166
-
-
Hahs, D.W.1
McCauley, J.L.2
Crunk, A.E.3
McFarland, L.L.4
Gaskell, P.C.5
Jiang, L.6
-
64
-
-
0035856462
-
Genome-wide linkage disequilibrium mapping of late-onset Alzheimer's disease in Finland
-
M. Hiltunen, A. Mannermaa, D. Thompson, D. Easton, M. Pirskanen, and S. Helisalmi et al. Genome-wide linkage disequilibrium mapping of late-onset Alzheimer's disease in Finland Neurology 57 2001 1663 1668
-
(2001)
Neurology
, vol.57
, pp. 1663-1668
-
-
Hiltunen, M.1
Mannermaa, A.2
Thompson, D.3
Easton, D.4
Pirskanen, M.5
Helisalmi, S.6
-
65
-
-
0032899712
-
A full genome scan for late onset Alzheimer's disease
-
P. Kehoe, F. Wavrant-De Vrieze, R. Crook, W.S. Wu, P. Holmans, and I. Fenton et al. A full genome scan for late onset Alzheimer's disease Hum Mol Genet 8 1999 237 245
-
(1999)
Hum Mol Genet
, vol.8
, pp. 237-245
-
-
Kehoe, P.1
Wavrant-De Vrieze, F.2
Crook, R.3
Wu, W.S.4
Holmans, P.5
Fenton, I.6
-
66
-
-
0033647304
-
Identification of novel genes in late-onset Alzheimer's disease
-
M.A. Pericak-Vance, J. Grubber, L.R. Bailey, D. Hedges, S. West, and L. Santoro et al. Identification of novel genes in late-onset Alzheimer's disease Exp Gerontol 35 2000 1343 1352
-
(2000)
Exp Gerontol
, vol.35
, pp. 1343-1352
-
-
Pericak-Vance, M.A.1
Grubber, J.2
Bailey, L.R.3
Hedges, D.4
West, S.5
Santoro, L.6
-
67
-
-
0032547332
-
Genetic studies on chromosome 12 in late-onset Alzheimer disease
-
W.S. Wu, P. Holmans, F. Wavrant-DeVrieze, S. Shears, P. Kehoe, and R. Crook et al. Genetic studies on chromosome 12 in late-onset Alzheimer disease JAMA 280 1998 619 622
-
(1998)
JAMA
, vol.280
, pp. 619-622
-
-
Wu, W.S.1
Holmans, P.2
Wavrant-Devrieze, F.3
Shears, S.4
Kehoe, P.5
Crook, R.6
-
68
-
-
0034704197
-
Susceptibility locus for Alzheimer's disease on chromosome 10
-
A. Myers, P. Holmans, H. Marshall, J. Kwon, D. Meyer, and D. Ramic et al. Susceptibility locus for Alzheimer's disease on chromosome 10 Science 290 2000 2304 2305
-
(2000)
Science
, vol.290
, pp. 2304-2305
-
-
Myers, A.1
Holmans, P.2
Marshall, H.3
Kwon, J.4
Meyer, D.5
Ramic, D.6
-
69
-
-
0034703979
-
Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees
-
N. Ertekin-Taner, N. Graff-Radford, L.H. Younkin, C. Eckman, M. Baker, and J. Adamson et al. Linkage of plasma Abeta42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees Science 290 2000 2303 2304
-
(2000)
Science
, vol.290
, pp. 2303-2304
-
-
Ertekin-Taner, N.1
Graff-Radford, N.2
Younkin, L.H.3
Eckman, C.4
Baker, M.5
Adamson, J.6
-
70
-
-
0034704198
-
Evidence for genetic linkage of Alzheimer's disease to chromosome 10q
-
L. Bertram, D. Blacker, K. Mullin, D. Keeney, J. Jones, and S. Basu et al. Evidence for genetic linkage of Alzheimer's disease to chromosome 10q Science 290 2000 2302 2303
-
(2000)
Science
, vol.290
, pp. 2302-2303
-
-
Bertram, L.1
Blacker, D.2
Mullin, K.3
Keeney, D.4
Jones, J.5
Basu, S.6
-
71
-
-
0032539723
-
Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation
-
S.R. Hughes, O. Khorkova, S. Goyal, J. Knaeblein, J. Heroux, and N.G. Riedel et al. Alpha2-macroglobulin associates with beta-amyloid peptide and prevents fibril formation Proc Natl Acad Sci U S A 95 1998 3275 3280
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 3275-3280
-
-
Hughes, S.R.1
Khorkova, O.2
Goyal, S.3
Knaeblein, J.4
Heroux, J.5
Riedel, N.G.6
-
72
-
-
36448994065
-
The heritability of abstract reasoning in Caribbean Latinos with familial Alzheimer disease
-
B. Johnson, V. Santana, N. Schupf, M.X. Tang, Y. Stern, and R. Mayeux et al. The heritability of abstract reasoning in Caribbean Latinos with familial Alzheimer disease Dement Geriatr Cogn Disord 24 2007 411 417
-
(2007)
Dement Geriatr Cogn Disord
, vol.24
, pp. 411-417
-
-
Johnson, B.1
Santana, V.2
Schupf, N.3
Tang, M.X.4
Stern, Y.5
Mayeux, R.6
-
73
-
-
1042288164
-
Genetic influences on memory performance in familial Alzheimer disease
-
J.H. Lee, A. Flaquer, Y. Stern, B. Tycko, and R. Mayeux Genetic influences on memory performance in familial Alzheimer disease Neurology 62 2004 414 421
-
(2004)
Neurology
, vol.62
, pp. 414-421
-
-
Lee, J.H.1
Flaquer, A.2
Stern, Y.3
Tycko, B.4
Mayeux, R.5
-
74
-
-
34247177933
-
The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort
-
J.H. Lee, R. Cheng, N. Schupf, J. Manly, R. Lantigua, and Y. Stern et al. The association between genetic variants in SORL1 and Alzheimer disease in an urban, multiethnic, community-based cohort Arch Neurol 64 2007 501 506
-
(2007)
Arch Neurol
, vol.64
, pp. 501-506
-
-
Lee, J.H.1
Cheng, R.2
Schupf, N.3
Manly, J.4
Lantigua, R.5
Stern, Y.6
-
75
-
-
33846613222
-
The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease
-
E. Rogaeva, Y. Meng, J.H. Lee, Y. Gu, T. Kawarai, and F. Zou et al. The neuronal sortilin-related receptor SORL1 is genetically associated with Alzheimer disease Nat Genet 39 2007 168 177
-
(2007)
Nat Genet
, vol.39
, pp. 168-177
-
-
Rogaeva, E.1
Meng, Y.2
Lee, J.H.3
Gu, Y.4
Kawarai, T.5
Zou, F.6
-
76
-
-
78651297619
-
Meta-analysis of the association between variants in SORL1 and Alzheimer disease
-
C. Reitz, R. Cheng, E. Rogaeva, J.H. Lee, S. Tokuhiro, and F. Zou et al. Meta-analysis of the association between variants in SORL1 and Alzheimer disease Arch Neurol 68 2011 99 106
-
(2011)
Arch Neurol
, vol.68
, pp. 99-106
-
-
Reitz, C.1
Cheng, R.2
Rogaeva, E.3
Lee, J.H.4
Tokuhiro, S.5
Zou, F.6
-
77
-
-
79952592605
-
Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals
-
J.H. Lee, R. Cheng, S. Barral, C. Reitz, M. Medrano, and R. Lantigua et al. Identification of novel loci for Alzheimer disease and replication of CLU, PICALM, and BIN1 in Caribbean Hispanic individuals Arch Neurol 68 2011 320 328
-
(2011)
Arch Neurol
, vol.68
, pp. 320-328
-
-
Lee, J.H.1
Cheng, R.2
Barral, S.3
Reitz, C.4
Medrano, M.5
Lantigua, R.6
-
78
-
-
84871206725
-
Genetic variants in the Fat and Obesity Associated (FTO) gene and risk of Alzheimer's disease
-
C. Reitz, G. Tosto, R. Mayeux, and J.A. Luchsinger Genetic variants in the Fat and Obesity Associated (FTO) gene and risk of Alzheimer's disease PLoS One 7 2012 e50354
-
(2012)
PLoS One
, vol.7
, pp. 50354
-
-
Reitz, C.1
Tosto, G.2
Mayeux, R.3
Luchsinger, J.A.4
-
79
-
-
34249777814
-
Variation in FTO contributes to childhood obesity and severe adult obesity
-
C. Dina, D. Meyre, S. Gallina, E. Durand, A. Korner, and P. Jacobson et al. Variation in FTO contributes to childhood obesity and severe adult obesity Nat Genet 39 2007 724 726
-
(2007)
Nat Genet
, vol.39
, pp. 724-726
-
-
Dina, C.1
Meyre, D.2
Gallina, S.3
Durand, E.4
Korner, A.5
Jacobson, P.6
-
80
-
-
79956263146
-
FTO, type 2 diabetes, and weight gain throughout adult life: A meta-analysis of 41,504 subjects from the Scandinavian HUNT, MDC, and MPP studies
-
J.K. Hertel, S. Johansson, E. Sonestedt, A. Jonsson, R.T. Lie, and C.G. Platou et al. FTO, type 2 diabetes, and weight gain throughout adult life: A meta-analysis of 41,504 subjects from the Scandinavian HUNT, MDC, and MPP studies Diabetes 60 2011 1637 1644
-
(2011)
Diabetes
, vol.60
, pp. 1637-1644
-
-
Hertel, J.K.1
Johansson, S.2
Sonestedt, E.3
Jonsson, A.4
Lie, R.T.5
Platou, C.G.6
-
81
-
-
79955711085
-
A genome-wide association study on obesity and obesity-related traits
-
K. Wang, W.D. Li, C.K. Zhang, Z. Wang, J.T. Glessner, and S.F. Grant et al. A genome-wide association study on obesity and obesity-related traits PLoS One 6 2011 e18939
-
(2011)
PLoS One
, vol.6
, pp. 18939
-
-
Wang, K.1
Li, W.D.2
Zhang, C.K.3
Wang, Z.4
Glessner, J.T.5
Grant, S.F.6
-
82
-
-
77952340870
-
A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly
-
A.J. Ho, J.L. Stein, X. Hua, S. Lee, D.P. Hibar, and A.D. Leow et al. A commonly carried allele of the obesity-related FTO gene is associated with reduced brain volume in the healthy elderly Proc Natl Acad Sci U S A 107 2010 8404 8409
-
(2010)
Proc Natl Acad Sci U S A
, vol.107
, pp. 8404-8409
-
-
Ho, A.J.1
Stein, J.L.2
Hua, X.3
Lee, S.4
Hibar, D.P.5
Leow, A.D.6
-
83
-
-
84863810310
-
Effect of genetic variation in LRRTM3 on risk of Alzheimer disease
-
C. Reitz, C. Conrad, K. Roszkowski, R.S. Rogers, and R. Mayeux Effect of genetic variation in LRRTM3 on risk of Alzheimer disease Arch Neurol 69 2012 894 900
-
(2012)
Arch Neurol
, vol.69
, pp. 894-900
-
-
Reitz, C.1
Conrad, C.2
Roszkowski, K.3
Rogers, R.S.4
Mayeux, R.5
-
84
-
-
84866771520
-
Genome-wide survey of large rare copy number variants in Alzheimer's disease among Caribbean hispanics
-
M. Ghani, D. Pinto, J.H. Lee, Y. Grinberg, C. Sato, and D. Moreno et al. Genome-wide survey of large rare copy number variants in Alzheimer's disease among Caribbean hispanics G3 (Bethesda) 2 2012 71 78
-
(2012)
G3 (Bethesda)
, vol.2
, pp. 71-78
-
-
Ghani, M.1
Pinto, D.2
Lee, J.H.3
Grinberg, Y.4
Sato, C.5
Moreno, D.6
-
85
-
-
81355142021
-
Association between variants in IDE-KIF11-HHEX and plasma amyloid beta levels
-
C. Reitz, R. Cheng, N. Schupf, J.H. Lee, P.D. Mehta, and E. Rogaeva et al. Association between variants in IDE-KIF11-HHEX and plasma amyloid beta levels Neurobiol Aging 33 199 2012 e113 197
-
(2012)
Neurobiol Aging
, vol.33
, Issue.199
, pp. 113-197
-
-
Reitz, C.1
Cheng, R.2
Schupf, N.3
Lee, J.H.4
Mehta, P.D.5
Rogaeva, E.6
-
86
-
-
0242321663
-
Genetic variation in a haplotype block spanning IDE influences Alzheimer disease
-
J.A. Prince, L. Feuk, H.F. Gu, B. Johansson, M. Gatz, and K. Blennow et al. Genetic variation in a haplotype block spanning IDE influences Alzheimer disease Hum Mutat 22 2003 363 371
-
(2003)
Hum Mutat
, vol.22
, pp. 363-371
-
-
Prince, J.A.1
Feuk, L.2
Gu, H.F.3
Johansson, B.4
Gatz, M.5
Blennow, K.6
-
87
-
-
1842765688
-
Genetic variants in a haplotype block spanning IDE are significantly associated with plasma Abeta42 levels and risk for Alzheimer disease
-
N. Ertekin-Taner, M. Allen, D. Fadale, L. Scanlin, L. Younkin, and R.C. Petersen et al. Genetic variants in a haplotype block spanning IDE are significantly associated with plasma Abeta42 levels and risk for Alzheimer disease Hum Mutat 23 2004 334 342
-
(2004)
Hum Mutat
, vol.23
, pp. 334-342
-
-
Ertekin-Taner, N.1
Allen, M.2
Fadale, D.3
Scanlin, L.4
Younkin, L.5
Petersen, R.C.6
-
88
-
-
0034038036
-
Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains
-
A. Perez, L. Morelli, J.C. Cresto, and E.M. Castano Degradation of soluble amyloid beta-peptides 1-40, 1-42, and the Dutch variant 1-40Q by insulin degrading enzyme from Alzheimer disease and control brains Neurochem Res 25 2000 247 255
-
(2000)
Neurochem Res
, vol.25
, pp. 247-255
-
-
Perez, A.1
Morelli, L.2
Cresto, J.C.3
Castano, E.M.4
-
89
-
-
0037390039
-
Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo
-
W. Farris, S. Mansourian, Y. Chang, L. Lindsley, E.A. Eckman, and M.P. Frosch et al. Insulin-degrading enzyme regulates the levels of insulin, amyloid beta-protein, and the beta-amyloid precursor protein intracellular domain in vivo Proc Natl Acad Sci U S A 100 2003 4162 4167
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 4162-4167
-
-
Farris, W.1
Mansourian, S.2
Chang, Y.3
Lindsley, L.4
Eckman, E.A.5
Frosch, M.P.6
-
90
-
-
70449528674
-
Polymorphisms within insulin-degrading enzyme (IDE) gene determine insulin metabolism and risk of type 2 diabetes
-
N. Rudovich, O. Pivovarova, E. Fisher, A. Fischer-Rosinsky, J. Spranger, and M. Mohlig et al. Polymorphisms within insulin-degrading enzyme (IDE) gene determine insulin metabolism and risk of type 2 diabetes J Mol Med (Berl) 87 2009 1145 1151
-
(2009)
J Mol Med (Berl)
, vol.87
, pp. 1145-1151
-
-
Rudovich, N.1
Pivovarova, O.2
Fisher, E.3
Fischer-Rosinsky, A.4
Spranger, J.5
Mohlig, M.6
-
91
-
-
0035860986
-
A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families
-
E.S. Athan, J. Williamson, A. Ciappa, V. Santana, S.N. Romas, and J.H. Lee et al. A founder mutation in presenilin 1 causing early-onset Alzheimer disease in unrelated Caribbean Hispanic families JAMA 286 2001 2257 2263
-
(2001)
JAMA
, vol.286
, pp. 2257-2263
-
-
Athan, E.S.1
Williamson, J.2
Ciappa, A.3
Santana, V.4
Romas, S.N.5
Lee, J.H.6
-
92
-
-
0036818747
-
A novel presenilin 1 mutation (L174 M) in a large Cuban family with early onset Alzheimer disease
-
A.M. Bertoli Avella, B. Marcheco Teruel, J.J. Llibre Rodriguez, N. Gomez Viera, I. Borrajero Martinez, and E.A. Severijnen et al. A novel presenilin 1 mutation (L174 M) in a large Cuban family with early onset Alzheimer disease Neurogenetics 4 2002 97 104
-
(2002)
Neurogenetics
, vol.4
, pp. 97-104
-
-
Bertoli Avella, A.M.1
Marcheco Teruel, B.2
Llibre Rodriguez, J.J.3
Gomez Viera, N.4
Borrajero Martinez, I.5
Severijnen, E.A.6
-
93
-
-
83455211863
-
A comprehensive genetic association study of Alzheimer disease in African Americans
-
M.W. Logue, M. Schu, B.N. Vardarajan, J. Buros, R.C. Green, and R.C. Go et al. A comprehensive genetic association study of Alzheimer disease in African Americans Arch Neurol 68 2011 1569 1579
-
(2011)
Arch Neurol
, vol.68
, pp. 1569-1579
-
-
Logue, M.W.1
Schu, M.2
Vardarajan, B.N.3
Buros, J.4
Green, R.C.5
Go, R.C.6
-
94
-
-
79952900481
-
Association of common KIBRA variants with episodic memory and AD risk
-
J.D. Burgess, O. Pedraza, N.R. Graff-Radford, M. Hirpa, F. Zou, and R. Miles et al. Association of common KIBRA variants with episodic memory and AD risk Neurobiol Aging 32 557 2011 e551 559
-
(2011)
Neurobiol Aging
, vol.32
, Issue.557
, pp. 551-559
-
-
Burgess, J.D.1
Pedraza, O.2
Graff-Radford, N.R.3
Hirpa, M.4
Zou, F.5
Miles, R.6
-
95
-
-
33750334020
-
Common Kibra alleles are associated with human memory performance
-
A. Papassotiropoulos, D.A. Stephan, M.J. Huentelman, F.J. Hoerndli, D.W. Craig, and J.V. Pearson et al. Common Kibra alleles are associated with human memory performance Science 314 2006 475 478
-
(2006)
Science
, vol.314
, pp. 475-478
-
-
Papassotiropoulos, A.1
Stephan, D.A.2
Huentelman, M.J.3
Hoerndli, F.J.4
Craig, D.W.5
Pearson, J.V.6
-
96
-
-
33746863741
-
Genetic association between endothelial nitric oxide synthase and Alzheimer disease
-
MIRAGE Study Group
-
Akomolafe A, Lunetta KL, Erlich PM, Cupples LA, Baldwin CT, Huyck M, et al.; MIRAGE Study Group (2006): Genetic association between endothelial nitric oxide synthase and Alzheimer disease. Clin Genet 70:49-56
-
(2006)
Clin Genet
, vol.70
, pp. 49-56
-
-
Akomolafe, A.1
Lunetta, K.L.2
Erlich, P.M.3
Cupples, L.A.4
Baldwin, C.T.5
Huyck, M.6
-
97
-
-
29644434198
-
Polymorphisms in the PON gene cluster are associated with Alzheimer disease
-
P.M. Erlich, K.L. Lunetta, L.A. Cupples, M. Huyck, R.C. Green, and C.T. Baldwin et al. Polymorphisms in the PON gene cluster are associated with Alzheimer disease Hum Mol Genet 15 2006 77 85
-
(2006)
Hum Mol Genet
, vol.15
, pp. 77-85
-
-
Erlich, P.M.1
Lunetta, K.L.2
Cupples, L.A.3
Huyck, M.4
Green, R.C.5
Baldwin, C.T.6
-
98
-
-
80855139971
-
The association of genetic variants in interleukin-1 genes with cognition: Findings from the cardiovascular health study
-
K.S. Benke, M.C. Carlson, B.Q. Doan, J.D. Walston, Q.L. Xue, and A.P. Reiner et al. The association of genetic variants in interleukin-1 genes with cognition: Findings from the cardiovascular health study Exp Gerontol 46 2011 1010 1019
-
(2011)
Exp Gerontol
, vol.46
, pp. 1010-1019
-
-
Benke, K.S.1
Carlson, M.C.2
Doan, B.Q.3
Walston, J.D.4
Xue, Q.L.5
Reiner, A.P.6
-
99
-
-
78649850501
-
Association of TTR polymorphisms with hippocampal atrophy in Alzheimer disease families
-
K.T. Cuenco, R. Friedland, C.T. Baldwin, J. Guo, B. Vardarajan, and K.L. Lunetta et al. Association of TTR polymorphisms with hippocampal atrophy in Alzheimer disease families Neurobiol Aging 32 2011 249 256
-
(2011)
Neurobiol Aging
, vol.32
, pp. 249-256
-
-
Cuenco, K.T.1
Friedland, R.2
Baldwin, C.T.3
Guo, J.4
Vardarajan, B.5
Lunetta, K.L.6
-
100
-
-
84864485341
-
Multiple loci influencing hippocampal degeneration identified by genome scan
-
S.A. Melville, J. Buros, A.R. Parrado, B. Vardarajan, M.W. Logue, and L. Shen et al. Multiple loci influencing hippocampal degeneration identified by genome scan Ann Neurol 72 2012 65 75
-
(2012)
Ann Neurol
, vol.72
, pp. 65-75
-
-
Melville, S.A.1
Buros, J.2
Parrado, A.R.3
Vardarajan, B.4
Logue, M.W.5
Shen, L.6
|