Common Kibra alleles are associated with human memory performance

Science

Volumn 314, Issue 5798, 2006, Pages 475-478

  Papassotiropoulos, Andreas ^a,b   Stephan, Dietrich A ^b   Huentelman, Matthew J ^b   Hoerndli, Frederic J ^a   Craig, David W ^b   Pearson, John V ^b   Huynh, Kim Dung ^a   Brunner, Fabienne ^a   Corneveaux, Jason ^b   Osborne, David ^c   Wollmer, M Axel ^a   Aerni, Amanda ^a   Coluccia, Daniel ^a   Hänggi, Jürgen ^a   Mondadori, Christian R A ^a   Buchmann, Andreas ^a   Reiman, Eric M ^b,d   Caselli, Richard J ^c   Henke, Katharina ^a   De Quervain, Dominique J F ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b TRANSLATIONAL GENOMICS RESEARCH INSTITUTE   (United States)

^c MAYO CLINIC   (United States)

^d UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN; CELLS; MAGNETIC RESONANCE IMAGING; MEDICAL IMAGING; NEUROLOGY; PROTEINS;

BRAIN PROTEINS; BRAIN STRUCTURES; HUMAN MEMORY; VARIANTS;

GENETIC ENGINEERING;

ALLELE; BRAIN; GENE EXPRESSION; GENOMICS; IMAGING METHOD; MEMORY; PROTEIN;

ADULT; AGED; ARTICLE; COGNITION; GENE; GENE EXPRESSION; GENE LOCUS; GENETIC VARIABILITY; GENOTYPE; HIPPOCAMPUS; HUMAN; HUMAN EXPERIMENT; KIBRA GENE; MAJOR CLINICAL STUDY; MEMORY; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM; SWITZERLAND; UNITED STATES;

ADOLESCENT; ADULT; ALLELES; ANIMALS; ATTENTION; BRAIN; BRAIN CHEMISTRY; CALCIUM-BINDING PROTEINS; COHORT STUDIES; FEMALE; GENE EXPRESSION; GENOTYPE; HAPLOTYPES; HIPPOCAMPUS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MEMBRANE PROTEINS; MEMORY; MICE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SWITZERLAND; UNITED STATES;

CENTRAL EUROPE; EURASIA; EUROPE; NORTH AMERICA; SWITZERLAND; UNITED STATES;

EID: 33750334020     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1129837     Document Type: Article

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31. Supported by grants from the Swiss National Science Foundation (PP00B-68859 to A.P., PP00B-106708 to D.Q., and 3100-067114 to K.H.), the Helmut-Horten Stiftung (D.Q. and A.P), the Hermann-Klaus Stiftung (D.Q.), the Emily Dorothy Lageman-EMDO Stiftung (D.Q.), the Olga Mayenfisch Stiftung (A.P.), the Baugarten Stiftung (A.P.), the National Institute of Mental Health (R01MH057899 to E.M.R), the National Institute on Aging (P30AG19610 to E.M.R.), the NIH Neuroscience Blueprint (U24N5051872 to D.A.S.), the Bisgrove charitable donation (D.A.5 and D.W.C.), the State of Arizona (D.A.S and E.M.R), and the Endgame UO1 grant U01HL086528-01 (D.A.S.). We gratefully acknowledge the Allen Brain Institute for the use of their elegant murine in situ resource. We thank J. Trent, J. Lemna, and D. Locke for assistance.