Reduction in amyloid A amyloid formation in apolipoprotein-E-deficient mice

American Journal of Pathology

Volumn 152, Issue 5, 1998, Pages 1387-1395

  Kindy, Mark S ^a,c   Rader, Daniel J ^b  

^a UNIVERSITY OF KENTUCKY   (United States)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^c UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; AMYLOID A PROTEIN; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E; CLUSTERIN; CONGO RED; DNA; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN; RNA; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

ADENOVIRUS; ALZHEIMER DISEASE; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE; HYPERLIPOPROTEINEMIA TYPE 3; IMMUNOCYTOCHEMISTRY; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ACUTE-PHASE PROTEINS; ADENOVIRIDAE; AMYLOIDOSIS; ANIMALS; APOLIPOPROTEIN E3; APOLIPOPROTEINS E; BLOTTING, SOUTHERN; CHOLESTEROL, HDL; DISEASE MODELS, ANIMAL; GLYCOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NUCLEIC ACIDS; POLYMERASE CHAIN REACTION; SERUM AMYLOID A PROTEIN; SILVER NITRATE; SPLEEN; TRIGLYCERIDES;

EID: 0031899218     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (47)

1. Namba Y, Tomonaga M, Kawasaki H, Otomo E, Ikeda K: Apolipoprotein E immunoreactivity in cerebral amyloid deposits and neurofibrillary tangles in Alzheimer's disease and kuru plaque amyloid in Creutzfeldt-Jacob disease. Brain Res 1991, 541:163-166
2. Wisniewski T, Frangione B: Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid. Neurosci Lett 1992, 135:235-238
3. Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak-Vance MA: Gene dose of apolippprotein E type 4 allele and the risk ot Alzheimer's disease in late onset families. Science 1993, 261:921-923
4. Saunders AM, Schmader K, Britner JCS, Benson MD, Brown WT, Goldfarb L, Goldgaber D, Manwaring MG, Szymanski MH, McCown N, Dole KC, Schmechel DE, Strittmatter WJ, Pericak-Vance MA, Roses AD: Apolipoprotein E ∈4 allele distribution in late-onset Alzheimer's disease and in other amyloid forming diseases. Lancet 1992, 342:710-711
5. Saunders AM, Strittmatter WJ, Schmechel D, George-Hyslop PH, Pericak-Vance MA, Joo SH, Rosi BL, Gusella JF, Crapper-MacLachlan DR, Albers MJ: Association of apolipoprotein E allele ∈4 with late-onset familial and sporadic Alzheimer's disease. Neurology 1993, 43:1467-1472
6. Mayeux R, Stern Y, Ottmen R, Talamichi TK, Tang M-X, Maestre G, Ngai C, Tycko B, Ginsberg H: The apolipoprotein ∈4 allele in patients with Alzheimer's disease. Ann Neurol 1993, 34:752-754
7. Poirier J, Davignon J, Bouthillier D, Kogan S, Bertrand P, Gauthier S: Apolipoprotein E polymorphism and Alzheimer's disease. Lancet 1993, 342:697-699
8. Ueki A, Kawano M, Namba Y, Kawakami M, Ikeda K: A high frequency of apolipoprotein E4 isoprotein in Japanese patients with late-onset nonfamilial Alzheimer's disease. Neurosci Lett 1993, 163: 166-168
9. Ohm TG, Kirca M, Bohl J, Scharnagl H, Gross W, Marz W: Apolipoprotein E polymorphism influences not only cerebral senile plaque load but also Alzheimer type neurofibrillary tangle formation. Neuroscience 1995, 66:583-587
10. Gomez IT, West HL, Rebeck GW, Harr SD, Growdon JH, Locascio JJ, Perls TT, Lipsitz LA, Hyman BT: Clinical and pathological correlates of apolipoprotein E ∈4 in Alzheimer's disease. Ann Neurol 1996, 39: 62-70
11. Selkoe DJ: The molecular pathology of Alzheimer's disease. Neuron 1991, 6:487-498
12. Kindy MS, de Beer FC, Marksbery WR, Pras M, Aksentijevich I, Kastner D, Kyle R, Soloman A, Woo P: Apolipoprotein E genotypes in AA and AL amyloidoses. Amyloid 1995, 2:159-162
13. Lovat LB, Booth SE, Booth DR, Madhoo S, Holmgren G, Hawkins PN, Soutar AK, Pepys MB: Apolipoprotein E4 genotype is not a risk factor for systemic AA amyloidosis or familial amyloid polyneuropathy. Amyloid 1995, 2:163-166
14. Castano EM, Prelli F, Pras M, Frangione B: Apolipoprotein E carboxylterminal fragmente are complexed to amyloids A and L: implications for amyloidogenesis and Alzheimer's disease. J Biol Chem 1995, 270:17610-17615
15. Strittmatter WJ, Saunders AM, Schmechel D, Pericak-Vance M, Enghild J, Salvesen GS, Roses AD: Apolipoprotein E: High-avidity binding to β-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease. Proc Natl Acad Sci USA 1993, 90:1977-1981
16. Strittmatter WJ, Weisgraber KH, Huang D, Dong L-M, Salvesen GS, Pericak Vance M, Schmechel D, Saunders AM, Goldgaber D, Roses AD: Binding of human apolipoprotein E to βA4 peptide: isoform-specific effects and implications for late-onset Alzheimer disease. Proc Natl Acad Sci USA 1993, 90:8098-8102
17. Evans KC, Berger EP, Cho CG, Weisgraber KH, Lansbury PT Jr: Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer's disease. Proc Natl Acad Sci USA 1995, 92:763-767
18. Wisniewski T, Castano EM, Golabek A, Vogel T, Frangione B: Acceleration of Alzheimer's fibril formation by apolipoprotein E in vitro. Am J Pathol 1994, 145:1030-1035
19. Ma J, Yee A, Brewer HB, Das S, Potter H: The amyloid-associated proteins αl-antichymotrypsin and apolipoprotein E promote the assembly of the Alzheimer β protein into filaments. Nature 1994, 372: 92-94
20. Sanan DA, Weisgraber KH, Russell SJ, Mahley RW, Huang D, Saunders A, Schmechel D, Wisniewski T, Frangione B, Roses AD: Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3. J Clin Invest 1994, 94:860-869
21. Wood SJ, Chan W, Wetzel R: Seeding of A beta fibril formation is inhibited by all three isotypes of apolipoprotein E. Biochemistry 1996, 35:12623-12628
22. McAdam KPWJ, Sipe JD: Murine model for human secondary amyloidosis: genetic variability of the acute-phase serum protein SAA response to endotoxin and casein. J Exp Med 1976, 144:1121-1127
23. Axelrad MA, Kisilevsky R, Willmer J, Chen SJ, Skinner M: Further characterization of amyloid-enhancing factor. Lab Invest 1982, 47: 139-146
24. Kindy MS, King AR, Perry G, de Beer MC, de Beer FC: Association of apolipoprotein E with murine amyloid A protein amyloid. Lab Invest 1995, 73:469-475
25. Tape C, Tan R, Nesheim M, Kisilevsky R: Direct evidence for circulating apoSAA as the precursor of tissue AA amyloid deposits. Scand J Immunol 1988, 28:317-324
26. Shiroo M, Kawahara E, Nakanishi I, Migita S: Specific deposition of serum amyloid A protein 2 in the mouse. Scand J Immunol 1987, 26:709-716
27. Brisette L, Young I, Narindrasorasak S, Kisilevsky R, Deeley R: Differential induction of serum amyloid-A gene family in response to an inflammatory agent and to amyloid-enhancing factor. J Biol Chem 1989, 264:19327-19332
28. Piedrahita JA, Zhang SH, Hagaman JR, Oliver PM, Macda N: Generation of mice carrying a mutant apolipoprotein E gene inactivated by gene targeting in embryonic stem cells. Proc Natl Acad Sci USA 1992, 89:4471-4475
29. Zhang SH, Reddick RL, Piedrahita JA, Maeda N: Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science 1992, 258:468-471
30. Chan W, Fornwald J, Brawner M, Wetzel R: Native complex formation between apolipoprotein E isoforms and the Alzheimer's disease peptide Aβ. Biochemistry 1996, 35:7123-7130
31. Kozarsky KF, McKinley DR, Austin LL, Raper SE, Stratford-Perricaudet LD, Wilson JM: In vivo correction of LDL receptor deficiency in the Watanabe heritable hyperlipidemic rabbit with recombinant adenoviruses. J Biol Chem 1994, 269:13695-13701
32. Webb NR, de Beer MC, van der Westhuyzen DR, Kindy MS, Banka CL, Tsukamoto K, Rader DJ, de Beer FC: Adenoviral vector-mediated over-expression of serum amyloid A in apoAl-deficient mice. J Lipid Res 1997, 38:1583-1590
33. de Beer MC, de Beer FC, Beach CM, Carreras I, Sipe JD: Mouse serum amyloid A protein: complete amino acid sequence and mRNA analysis of a new isoform. Biochem J 1992, 283:673-678
34. Strachan AF, de Beer FC, van der Weshuyzen DR, Coetzee GA: Identification of three isoform patterns of human serum amyloid A protein. Biochem J 1988, 250:203-207
35. Sipe JD, Carreras I, Gonnerman WA, Cathcart ES, de Beer MC, de Beer FC: Characterization of the inbred CE/J mouse strain as amyloid resistant. Am J Pathol 1993, 143:1480-1485
36. Shirahama T, Miura K, Ju S-T, Kisilevsky R, Gruys E, Cohen AS: Amyloid enhancing factor-loaded macrophages in amyloid fibril formation. Lab Invest 1990, 62:61-69
37. Kisilevsky R: Common elements in amyloidosis. Amyloid and Amyloidosis, VIth International Symposium on Amyloidosis. Edited by Natvig JB, Forre O, Husby G, Husebekk A, Skogen B, Sletten K, Westermark P. Dordrecht, The Netherlands, Kluwer Academic Publishers, 1990, pp 251-257
38. Inoue S, Kisilevsky R: A high resolution ultrastructural study of experimental murine AA amyloid. Lab Invest 1996, 74:670-683
39. Snow AD, Bramson R, Mar H, Wight TN, Kisilevsky R: A temporal and ultrastructural relationship between heparan sulfate proteoglycans and AA amyloid in experimental amyloidosis. J Histochem Cytochem 1991, 39:1321-1330
40. Matsubara E, Frangione B, Ghiso J: Characterization of apolipoprotein J-Alzheimer's Aβ interaction. J Biol Chem 1995, 270:7563-7567
41. Koudinov A, Matsubara E,Frangione B, Ghiso J: The soluble form of Alzheimer's amyloid beta protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma. Biochem Biophys Res Commun 1994, 205:1164-1171
42. Matsubara E, Soto C, Governale S, Frangione B, Ghiso J: Apolipoprotein J and Alzheimer's amyloid β3 solubility. Biochem J 1996, 316:671-679
43. Allies L, Kisilevsky R, Young ID: Induction of perlecan gene expression precedes amyloid formation during experimental murine amyloidogenesis. Lab Invest 1993, 69:443-448
44. McCubbin WD, Kay CM, Narindrasorasak S, Kisilevsky R: Circular-dichroism studies on two murine serum amyloid A proteins. Biochem J 1988, 256:775-783
45. Kisilevsky R, Lemieux LJ, Fraser PE, Kong XQ, Hultin PG, Szarek WA: Arresting amyloidosis in vivo using small-molecule anionic sulphonates or sulphates: implications for Alzheimer's disease. Nature Med 1995, 1:143-148
46. Botto M, Hawkins PN, Bickerstaff MCM, Herbert J, Bygrave AK, McBride A, Hutchinson WL, Tennent GA, Walport MJ, Pepys MB: Amyloid deposition is delayed in mice with targeted deletion of the serum amyloid P component gene. Nature Med 1997, 3:855-859
47. Hoshii Y, Kawano H, Cui D, Takeda T, Gondo T, Takahashi M, Kogishi K, Highuchi K, Ishihara T: Amyloid A protein amyloidosis induced in apolipoprotein-E deficient mice. Am J Pathol 1997, 151:911-917