-
1
-
-
0034017850
-
GOLD - Graphical overview of linkage disequilibrium
-
Abecasis GR, Cookson WO. 2000. GOLD - graphical overview of linkage disequilibrium. Bioinformatics 16:182-183.
-
(2000)
Bioinformatics
, vol.16
, pp. 182-183
-
-
Abecasis, G.R.1
Cookson, W.O.2
-
2
-
-
0035687018
-
Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease
-
Abraham R, Myers A, Wavrant-DeVrieze F, Hamshere ML, Thomas HV, Marshall H, Compton D, Spurlock G, Turic D, Hoogendoorn B, Kwon JM, Petersen RC, Tangalos E, Norton J, Morris JC, Bullock R, Liolitsa D, Lovestone S, Hardy J, Goate A, O'Donovan M, Williams J, Owen MJ, Jones L. 2001. Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease. Hum Genet 109:646-652.
-
(2001)
Hum Genet
, vol.109
, pp. 646-652
-
-
Abraham, R.1
Myers, A.2
Wavrant-DeVrieze, F.3
Hamshere, M.L.4
Thomas, H.V.5
Marshall, H.6
Compton, D.7
Spurlock, G.8
Turic, D.9
Hoogendoorn, B.10
Kwon, J.M.11
Petersen, R.C.12
Tangalos, E.13
Norton, J.14
Morris, J.C.15
Bullock, R.16
Liolitsa, D.17
Lovestone, S.18
Hardy, J.19
Goate, A.20
O'Donovan, M.21
Williams, J.22
Owen, M.J.23
Jones, L.24
more..
-
3
-
-
0037036168
-
Confirmation of association between D10S583 and Alzheimer's disease in a case-control sample
-
Ait-Ghezala G, Abdullah L, Crescentini R, Crawford F, Town T, Singh S, Richards D, Duara R, Mullan M. 2002. Confirmation of association between D10S583 and Alzheimer's disease in a case-control sample. Neurosci Lett 325:87-90.
-
(2002)
Neurosci Lett
, vol.325
, pp. 87-90
-
-
Ait-Ghezala, G.1
Abdullah, L.2
Crescentini, R.3
Crawford, F.4
Town, T.5
Singh, S.6
Richards, D.7
Duara, R.8
Mullan, M.9
-
4
-
-
0031966959
-
Multipoint quantitative-trait linkage analysis in general pedigrees
-
Almasy L, Blangero J. 1998. Multipoint quantitative-trait linkage analysis in general pedigrees. Am J Hum Genet 62:1198-1211.
-
(1998)
Am J Hum Genet
, vol.62
, pp. 1198-1211
-
-
Almasy, L.1
Blangero, J.2
-
5
-
-
0034704198
-
Evidence for genetic linkage of Alzheimer's disease to chromosome 10q
-
Bertram L, Blacker D, Mullin K, Keeney D, Jones J, Basu S, Yhu S, McInnis MG, Go RC, Vekrellis K, Selkoe DJ, Saunders AJ, Tanzi RE. 2000. Evidence for genetic linkage of Alzheimer's disease to chromosome 10q. Science 290:2302-2303.
-
(2000)
Science
, vol.290
, pp. 2302-2303
-
-
Bertram, L.1
Blacker, D.2
Mullin, K.3
Keeney, D.4
Jones, J.5
Basu, S.6
Yhu, S.7
McInnis, M.G.8
Go, R.C.9
Vekrellis, K.10
Selkoe, D.J.11
Saunders, A.J.12
Tanzi, R.E.13
-
6
-
-
12244296117
-
Results of a high-resolution genome screen of 437 Alzheimer's disease families
-
Blacker D, Bertram L, Saunders AJ, Moscarillo TJ, Albert MS, Wiener H, Perry RT, Collins JS, Harrell LE, Go RC, Mahoney A, Beaty T, Fallin MD, Avramopoulos D, Chase GA, Folstein MF, McInnis MG, Bassett SS, Doheny KJ, Pugh EW, Tanzi RE. 2003. Results of a high-resolution genome screen of 437 Alzheimer's disease families. Hum Mol Genet 12:23-32.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 23-32
-
-
Blacker, D.1
Bertram, L.2
Saunders, A.J.3
Moscarillo, T.J.4
Albert, M.S.5
Wiener, H.6
Perry, R.T.7
Collins, J.S.8
Harrell, L.E.9
Go, R.C.10
Mahoney, A.11
Beaty, T.12
Fallin, M.D.13
Avramopoulos, D.14
Chase, G.A.15
Folstein, M.F.16
McInnis, M.G.17
Bassett, S.S.18
Doheny, K.J.19
Pugh, E.W.20
Tanzi, R.E.21
more..
-
7
-
-
0022649864
-
The use of measured genotype information in the analysis of quantitative phenotypes in man. I. Models and analytical methods
-
Boerwinkle E, Chakraborty R, Sing CF. 1986. The use of measured genotype information in the analysis of quantitative phenotypes in man. I. Models and analytical methods. Ann Hum Genet 50:181-194.
-
(1986)
Ann Hum Genet
, vol.50
, pp. 181-194
-
-
Boerwinkle, E.1
Chakraborty, R.2
Sing, C.F.3
-
8
-
-
0030293676
-
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo
-
Borchelt DR, Thinakaran G, Eckman CB, Lee MK, Davenport F, Ratovitsky T, Prada CM, Kim G, Seekins S, Yager D, Slunt HH, Wang R, Seeger M, Levey AI, Gandy SE, Copeland NG, Jenkins NA, Price DL, Younkin SG, Sisodia SS. 1996. Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/ 1-40 ratio in vitro and in vivo. Neuron 17: 1005-1013.
-
(1996)
Neuron
, vol.17
, pp. 1005-1013
-
-
Borchelt, D.R.1
Thinakaran, G.2
Eckman, C.B.3
Lee, M.K.4
Davenport, F.5
Ratovitsky, T.6
Prada, C.M.7
Kim, G.8
Seekins, S.9
Yager, D.10
Slunt, H.H.11
Wang, R.12
Seeger, M.13
Levey, A.I.14
Gandy, S.E.15
Copeland, N.G.16
Jenkins, N.A.17
Price, D.L.18
Younkin, S.G.19
Sisodia, S.S.20
more..
-
9
-
-
0037162647
-
Polymorphisms of insulin degrading enzyme gene are not associated with Alzheimer's disease
-
Boussaha M, Hannequin D, Verpillat P, Brice A, Frebourg T, Campion D. 2002. Polymorphisms of insulin degrading enzyme gene are not associated with Alzheimer's disease. Neurosci Lett 329:121-123.
-
(2002)
Neurosci Lett
, vol.329
, pp. 121-123
-
-
Boussaha, M.1
Hannequin, D.2
Verpillat, P.3
Brice, A.4
Frebourg, T.5
Campion, D.6
-
10
-
-
0027526419
-
Release of excess amyloid beta protein from a mutant amyloid beta protein precursor
-
Cai XD, Golde TE, Younkin SG. 1993. Release of excess amyloid beta protein from a mutant amyloid beta protein precursor. Science 259:514-516.
-
(1993)
Science
, vol.259
, pp. 514-516
-
-
Cai, X.D.1
Golde, T.E.2
Younkin, S.G.3
-
11
-
-
0026745610
-
Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production
-
Citron M, Oltersdorf T, Haass C, McConlogue L, Hung AY, Seubert P, Vigo-Pelfrey C, Lieberburg I, Selkoe DJ. 1992. Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production. Nature 360:672-674.
-
(1992)
Nature
, vol.360
, pp. 672-674
-
-
Citron, M.1
Oltersdorf, T.2
Haass, C.3
McConlogue, L.4
Hung, A.Y.5
Seubert, P.6
Vigo-Pelfrey, C.7
Lieberburg, I.8
Selkoe, D.J.9
-
12
-
-
16944362157
-
Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice
-
Citron M, Westaway D, Xia W, Carlson G, Diehl T, Levesque G, Johnson-Wood K, Lee M, Seubert P, Davis A, Kholodenko D, Motter R, Sherrington R, Perry B, Yao H, Strome R, Lieberburg I, Rommens J, Kim S, Schenk D, Fraser P, St George Hyslop P, Selkoe DJ. 1997. Mutant presenilins of Alzheimer's disease increase production of 42-residue amyloid beta-protein in both transfected cells and transgenic mice. Nat Med 3:67-72.
-
(1997)
Nat Med
, vol.3
, pp. 67-72
-
-
Citron, M.1
Westaway, D.2
Xia, W.3
Carlson, G.4
Diehl, T.5
Levesque, G.6
Johnson-Wood, K.7
Lee, M.8
Seubert, P.9
Davis, A.10
Kholodenko, D.11
Motter, R.12
Sherrington, R.13
Perry, B.14
Yao, H.15
Strome, R.16
Lieberburg, I.17
Rommens, J.18
Kim, S.19
Schenk, D.20
Fraser, P.21
St. George Hyslop, P.22
Selkoe, D.J.23
more..
-
13
-
-
0027194791
-
Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families
-
Corder EH, Saunders AM, Strittmatter WJ, Schmechel DE, Gaskell PC, Small GW, Roses AD, Haines JL, Pericak-Vance MA. 1993. Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. Science 261:921-923.
-
(1993)
Science
, vol.261
, pp. 921-923
-
-
Corder, E.H.1
Saunders, A.M.2
Strittmatter, W.J.3
Schmechel, D.E.4
Gaskell, P.C.5
Small, G.W.6
Roses, A.D.7
Haines, J.L.8
Pericak-Vance, M.A.9
-
14
-
-
16044366039
-
Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin1
-
Duff K, Eckman C, Zehr C, Yu X, Prada CM, Perez-Tur J, Hutton M, Buee L, Harigaya Y, Yager D, Morgan D, Gordon MN, Holcomb L, Refolo L, Zenk B, Hardy J, Younkin S. 1996. Increased amyloid-beta42(43) in brains of mice expressing mutant presenilin1. Nature 383:710-713.
-
(1996)
Nature
, vol.383
, pp. 710-713
-
-
Duff, K.1
Eckman, C.2
Zehr, C.3
Yu, X.4
Prada, C.M.5
Perez-Tur, J.6
Hutton, M.7
Buee, L.8
Harigaya, Y.9
Yager, D.10
Morgan, D.11
Gordon, M.N.12
Holcomb, L.13
Refolo, L.14
Zenk, B.15
Hardy, J.16
Younkin, S.17
-
15
-
-
0038519618
-
Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: Evidence of effect modification by apolipoprotein E (APOE)
-
Edland SD, Wavrant-De Vriese F, Compton D, Smith GE, Ivnik R, Boeve BF, Tangalos EG, Petersen RC. 2003. Insulin degrading enzyme (IDE) genetic variants and risk of Alzheimer's disease: evidence of effect modification by apolipoprotein E (APOE). Neurosci Lett 345:21-24.
-
(2003)
Neurosci Lett
, vol.345
, pp. 21-24
-
-
Edland, S.D.1
Wavrant-De Vriese, F.2
Compton, D.3
Smith, G.E.4
Ivnik, R.5
Boeve, B.F.6
Tangalos, E.G.7
Petersen, R.C.8
-
16
-
-
0035399728
-
SNP association studies in Alzheimer's disease highlight problems for complex disease analysis
-
Emahazion T, Feuk L, Jobs M, Sawyer SL, Fredman D, St Clair D, Prince JA, Brookes AJ. 2001. SNP association studies in Alzheimer's disease highlight problems for complex disease analysis. Trends Genet 17:407-413.
-
(2001)
Trends Genet
, vol.17
, pp. 407-413
-
-
Emahazion, T.1
Feuk, L.2
Jobs, M.3
Sawyer, S.L.4
Fredman, D.5
St. Clair, D.6
Prince, J.A.7
Brookes, A.J.8
-
17
-
-
0034703979
-
Linkage of plasma Aβ42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees
-
Ertekin-Taner N, Graff-Radford N, Younkin LH, Eckman C, Baker M, Adamson J, Ronald J, Blangero J, Hutton M, Younkin SG. 2000. Linkage of plasma Aβ42 to a quantitative locus on chromosome 10 in late-onset Alzheimer's disease pedigrees. Science 290:2303-2304.
-
(2000)
Science
, vol.290
, pp. 2303-2304
-
-
Ertekin-Taner, N.1
Graff-Radford, N.2
Younkin, L.H.3
Eckman, C.4
Baker, M.5
Adamson, J.6
Ronald, J.7
Blangero, J.8
Hutton, M.9
Younkin, S.G.10
-
18
-
-
0034936365
-
Heritability of plasma Aβ levels in typical late onset Alzheimer's disease pedigrees
-
Ertekin-Taner N, Graff-Radford N, Younkin L, Eckman C, Adamson J, Schaid D, Blangero J, Hutton M, Younkin S. 2001. Heritability of plasma Aβ levels in typical late onset Alzheimer's disease pedigrees. Genetic Epidemiology 21:19-30.
-
(2001)
Genetic Epidemiology
, vol.21
, pp. 19-30
-
-
Ertekin-Taner, N.1
Graff-Radford, N.2
Younkin, L.3
Eckman, C.4
Adamson, J.5
Schaid, D.6
Blangero, J.7
Hutton, M.8
Younkin, S.9
-
19
-
-
0344668728
-
Fine mapping of the (alpha)-T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer's disease pedigrees
-
Ertekin-Taner N, Ronald J, Asahara H, Younkin L, Hella M, Jain S, Gnida E, Younkin S, Fadale D, Ohyagi Y, Singleton A, Scanlin L, De Andrade M, Petersen R, Graff-Radford N, Hutton M. 2003. Fine mapping of the (alpha)-T catenin gene to a quantitative trait locus on chromosome 10 in late-onset Alzheimer's disease pedigrees. Hum Mol Genet 12:3133-3143.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 3133-3143
-
-
Ertekin-Taner, N.1
Ronald, J.2
Asahara, H.3
Younkin, L.4
Hella, M.5
Jain, S.6
Gnida, E.7
Younkin, S.8
Fadale, D.9
Ohyagi, Y.10
Singleton, A.11
Scanlin, L.12
De Andrade, M.13
Petersen, R.14
Graff-Radford, N.15
Hutton, M.16
-
20
-
-
0029130796
-
Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population
-
Excoffier L, Slatkin M. 1995. Maximum-likelihood estimation of molecular haplotype frequencies in a diploid population. Mol Biol Evol 12:921-927.
-
(1995)
Mol Biol Evol
, vol.12
, pp. 921-927
-
-
Excoffier, L.1
Slatkin, M.2
-
21
-
-
0030823158
-
Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis
-
APOE and Alzheimer Disease Meta Analysis Consortium
-
Farrer LA, Cupples LA, Haines JL, Hyman B, Kukull WA, Mayeux R, Myers RH, Pericak-Vance MA, Risch N, van Duijn CM. 1997. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis. APOE and Alzheimer Disease Meta Analysis Consortium. JAMA 278:1349-1356.
-
(1997)
JAMA
, vol.278
, pp. 1349-1356
-
-
Farrer, L.A.1
Cupples, L.A.2
Haines, J.L.3
Hyman, B.4
Kukull, W.A.5
Mayeux, R.6
Myers, R.H.7
Pericak-Vance, M.A.8
Risch, N.9
Van Duijn, C.M.10
-
22
-
-
0036081484
-
HGVbase: A human sequence variation database emphasizing data quality and a broad spectrum of data sources
-
Fredman D, Siegfried M, Yuan YP, Bork P, Lehvaslaiho H, Brookes AJ. 2002. HGVbase: a human sequence variation database emphasizing data quality and a broad spectrum of data sources. Nucleic Acids Res 30:387-391.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 387-391
-
-
Fredman, D.1
Siegfried, M.2
Yuan, Y.P.3
Bork, P.4
Lehvaslaiho, H.5
Brookes, A.J.6
-
23
-
-
0019920786
-
Extensions to multivariate normal models for pedigree analysis
-
Hopper JL, Mathews JD. 1982. Extensions to multivariate normal models for pedigree analysis. Ann Hum Genet 46:373-383.
-
(1982)
Ann Hum Genet
, vol.46
, pp. 373-383
-
-
Hopper, J.L.1
Mathews, J.D.2
-
25
-
-
0034741031
-
alphaT-catenin: A novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion
-
Janssens B, Goossens S, Staes K, Gilbert B, van Hengel J, Colpaert C, Bruyneel E, Mareel M, van Roy F. 2001. alphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion. J Cell Sci 114:3177-3188.
-
(2001)
J Cell Sci
, vol.114
, pp. 3177-3188
-
-
Janssens, B.1
Goossens, S.2
Staes, K.3
Gilbert, B.4
Van Hengel, J.5
Colpaert, C.6
Bruyneel, E.7
Mareel, M.8
Van Roy, F.9
-
26
-
-
0028176821
-
Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme
-
Kurochkin IV, Goto S. 1994. Alzheimer's beta-amyloid peptide specifically interacts with and is degraded by insulin degrading enzyme. FEBS Lett 345:33-37.
-
(1994)
FEBS Lett
, vol.345
, pp. 33-37
-
-
Kurochkin, I.V.1
Goto, S.2
-
27
-
-
18344393780
-
Age at onset in two common neurodegenerative diseases is genetically controlled
-
Li YJ, Scott WK, Hedges DJ, Zhang F, Gaskell PC, Nance MA, Watts RL, Hubble JP, Koller WC, Pahwa R, Stern MB, Hiner BC, Jankovic J, Allen FA Jr, Goetz CG, Mastaglia F, Stajich JM, Gibson RA, Middleton LT, Saunders AM, Scott BL, Small GW, Nicodemus KK, Reed AD, Schmechel DE, Welsh-Bohmer KA, Conneally PM, Roses AD, Gilbert JR, Vance JM, Haines JL, Pericak-Vance MA. 2002. Age at onset in two common neurodegenerative diseases is genetically controlled. Am J Hum Genet 70:985-993.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 985-993
-
-
Li, Y.J.1
Scott, W.K.2
Hedges, D.J.3
Zhang, F.4
Gaskell, P.C.5
Nance, M.A.6
Watts, R.L.7
Hubble, J.P.8
Koller, W.C.9
Pahwa, R.10
Stern, M.B.11
Hiner, B.C.12
Jankovic, J.13
Allen Jr., F.A.14
Goetz, C.G.15
Mastaglia, F.16
Stajich, J.M.17
Gibson, R.A.18
Middleton, L.T.19
Saunders, A.M.20
Scott, B.L.21
Small, G.W.22
Nicodemus, K.K.23
Reed, A.D.24
Schmechel, D.E.25
Welsh-Bohmer, K.A.26
Conneally, P.M.27
Roses, A.D.28
Gilbert, J.R.29
Vance, J.M.30
Haines, J.L.31
Pericak-Vance, M.A.32
more..
-
28
-
-
0000951097
-
The evolutionary dynamics of complex polymorphisms
-
Lewontin RC, Kojima K. 1960. The evolutionary dynamics of complex polymorphisms. Evolution 14:450-472.
-
(1960)
Evolution
, vol.14
, pp. 450-472
-
-
Lewontin, R.C.1
Kojima, K.2
-
29
-
-
0037312921
-
Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
-
Lohmueller KE, Pearce CL, Pike M, Lander ES, Hirschhorn JN. 2003. Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 33:177-182.
-
(2003)
Nat Genet
, vol.33
, pp. 177-182
-
-
Lohmueller, K.E.1
Pearce, C.L.2
Pike, M.3
Lander, E.S.4
Hirschhorn, J.N.5
-
30
-
-
0034704197
-
Susceptibility locus for Alzheimer's disease on chromosome 10
-
Myers A, Holmans P, Marshall H, Kwon J, Meyer D, Ramic D, Shears S, Booth J, DeVrieze FW, Crook R, Hamshere M, Abraham R, Tunstall N, Rice F, Carty S, Lillystone S, Kehoe P, Rudrasingham V, Jones L, Lovestone S, Perez-Tur J, Williams J, Owen MJ, Hardy J, Goate AM. 2000. Susceptibility locus for Alzheimer's disease on chromosome 10. Science 290:2304-2305.
-
(2000)
Science
, vol.290
, pp. 2304-2305
-
-
Myers, A.1
Holmans, P.2
Marshall, H.3
Kwon, J.4
Meyer, D.5
Ramic, D.6
Shears, S.7
Booth, J.8
DeVrieze, F.W.9
Crook, R.10
Hamshere, M.11
Abraham, R.12
Tunstall, N.13
Rice, F.14
Carty, S.15
Lillystone, S.16
Kehoe, P.17
Rudrasingham, V.18
Jones, L.19
Lovestone, S.20
Perez-Tur, J.21
Williams, J.22
Owen, M.J.23
Hardy, J.24
Goate, A.M.25
more..
-
31
-
-
18244407351
-
Full genome screen for Alzheimer disease: Stage II analysis
-
Myers A, Wavrant De-Vrieze F, Holmans P, Hamshere M, Crook R, Compton D, Marshall H, Meyer D, Shears S, Booth J, Ramic D, Knowles H, Morris JC, Williams N, Norton N, Abraham R, Kehoe P, Williams H, Rudrasingham V, Rice F, Giles P, Tunstall N, Jones L, Lovestone S, Williams J, Owen MJ, Hardy J, Goate A. 2002. Full genome screen for Alzheimer disease: stage II analysis. Am J Med Genet 114:235-244.
-
(2002)
Am J Med Genet
, vol.114
, pp. 235-244
-
-
Myers, A.1
Wavrant De-Vrieze, F.2
Holmans, P.3
Hamshere, M.4
Crook, R.5
Compton, D.6
Marshall, H.7
Meyer, D.8
Shears, S.9
Booth, J.10
Ramic, D.11
Knowles, H.12
Morris, J.C.13
Williams, N.14
Norton, N.15
Abraham, R.16
Kehoe, P.17
Williams, H.18
Rudrasingham, V.19
Rice, F.20
Giles, P.21
Tunstall, N.22
Jones, L.23
Lovestone, S.24
Williams, J.25
Owen, M.J.26
Hardy, J.27
Goate, A.28
more..
-
32
-
-
0036138183
-
Bayesian haplotype inference for multiple linked single-nucleotide polymorphisms
-
Niu T, Qin ZS, Xu X, Liu JS. 2002. Bayesian haplotype inference for multiple linked single-nucleotide polymorphisms. Am J Hum Genet 70:157-169.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 157-169
-
-
Niu, T.1
Qin, Z.S.2
Xu, X.3
Liu, J.S.4
-
33
-
-
0242321663
-
Genetic variation in a haplotype block spanning IDE influences Alzheimer disease
-
Prince JA, Feuk L, Gu HF, Johansson B, Gatz M, Blennow K, Brookes AJ. 2003. Genetic variation in a haplotype block spanning IDE influences Alzheimer disease. Hum Mutat 22:363-371.
-
(2003)
Hum Mutat
, vol.22
, pp. 363-371
-
-
Prince, J.A.1
Feuk, L.2
Gu, H.F.3
Johansson, B.4
Gatz, M.5
Blennow, K.6
Brookes, A.J.7
-
34
-
-
0000398342
-
Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation
-
Qiu WQ, Walsh DM, Ye Z, Vekrellis K, Zhang J, Podlisny MB, Rosner MR, Safavi A, Hersh LB, Selkoe DJ. 1998. Insulin-degrading enzyme regulates extracellular levels of amyloid beta-protein by degradation. J Biol Chem 273: 32730-32738.
-
(1998)
J Biol Chem
, vol.273
, pp. 32730-32738
-
-
Qiu, W.Q.1
Walsh, D.M.2
Ye, Z.3
Vekrellis, K.4
Zhang, J.5
Podlisny, M.B.6
Rosner, M.R.7
Safavi, A.8
Hersh, L.B.9
Selkoe, D.J.10
-
35
-
-
16044373524
-
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease
-
Scheuner D, Eckman C, Jensen M, Song X, Citron M, Suzuki N, Bird TD, Hardy J, Hutton M, Kukull W, Larson E, Levy-Lahad E, Viitanen M, Peskind E, Poorkaj P, Schellenberg G, Tanzi R, Wasco W, Lannfelt L, Selkoe D, Younkin S. 1996. Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease. Nat Med 2:864-870.
-
(1996)
Nat Med
, vol.2
, pp. 864-870
-
-
Scheuner, D.1
Eckman, C.2
Jensen, M.3
Song, X.4
Citron, M.5
Suzuki, N.6
Bird, T.D.7
Hardy, J.8
Hutton, M.9
Kukull, W.10
Larson, E.11
Levy-Lahad, E.12
Viitanen, M.13
Peskind, E.14
Poorkaj, P.15
Schellenberg, G.16
Tanzi, R.17
Wasco, W.18
Lannfelt, L.19
Selkoe, D.20
Younkin, S.21
more..
-
36
-
-
0028909113
-
Monte Carlo tests for associations between disease and alleles at highly polymorphic loci
-
Sham PC, Curtis D. 1995. Monte Carlo tests for associations between disease and alleles at highly polymorphic loci. Ann Human Genet 59:97-105.
-
(1995)
Ann Human Genet
, vol.59
, pp. 97-105
-
-
Sham, P.C.1
Curtis, D.2
-
37
-
-
0029004341
-
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease
-
Sherrington R, Rogaev EI, Liang Y, Rogaeva EA, Levesque G, Ikeda M, Chi H, Lin C, Li G, Holman K, Tsuda T, Mar L, Foncin J-F, Bruni AC, Montesi MP, Sorbi S, Raincro I, Pinessi L, Nee L, Chumakov I, Pollen D, Brookes A, Sanseau P, Polinsky RJ, Wasco W, Da Silva HAR, Haines JL, Pericak-Vance MA, Tanzi RE, Roses AD, Fraser PE, Rommens JM, St. George-Hyslop PH. 1995. Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. Nature 375:754-760.
-
(1995)
Nature
, vol.375
, pp. 754-760
-
-
Sherrington, R.1
Rogaev, E.I.2
Liang, Y.3
Rogaeva, E.A.4
Levesque, G.5
Ikeda, M.6
Chi, H.7
Lin, C.8
Li, G.9
Holman, K.10
Tsuda, T.11
Mar, L.12
Foncin, J.-F.13
Bruni, A.C.14
Montesi, M.P.15
Sorbi, S.16
Raincro, I.17
Pinessi, L.18
Nee, L.19
Chumakov, I.20
Pollen, D.21
Brookes, A.22
Sanseau, P.23
Polinsky, R.J.24
Wasco, W.25
Da Silva, H.A.R.26
Haines, J.L.27
Pericak-Vance, M.A.28
Tanzi, R.E.29
Roses, A.D.30
Fraser, P.E.31
Rommens, J.M.32
St. George-Hyslop, P.H.33
more..
-
38
-
-
0029945706
-
Descent graphs in pedigree analysis: Applications to haplotyping, location scores, and marker-sharing statistics
-
Sobel E, Lange K. 1996. Descent graphs in pedigree analysis: applications to haplotyping, location scores, and marker-sharing statistics. Am J Hum Genet 58:1323-1337.
-
(1996)
Am J Hum Genet
, vol.58
, pp. 1323-1337
-
-
Sobel, E.1
Lange, K.2
-
39
-
-
0034193350
-
Linkage analysis demonstrates that the prothrombin G20210A mutation jointly influences plasma prothrombin levels and risk of thrombosis
-
Soria JM, Almasy L, Souto JC, Tirado I, Borell M, Mateo J, Slifer S, Stone W, Blangero J, Fontcuberta J. 2000. Linkage analysis demonstrates that the prothrombin G20210A mutation jointly influences plasma prothrombin levels and risk of thrombosis. Blood 95:2780-2785.
-
(2000)
Blood
, vol.95
, pp. 2780-2785
-
-
Soria, J.M.1
Almasy, L.2
Souto, J.C.3
Tirado, I.4
Borell, M.5
Mateo, J.6
Slifer, S.7
Stone, W.8
Blangero, J.9
Fontcuberta, J.10
-
40
-
-
18244384262
-
A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic disease
-
Soria JM, Almasy L, Souto JC, Bacq D, Buil A, Faure A, Martinez-Marchan E, Mateo J, Borrell M, Stone W, Lathrop M, Fontcuberta J, Blangero J. 2002. A quantitative-trait locus in the human factor XII gene influences both plasma factor XII levels and susceptibility to thrombotic disease. Am J Hum Genet 70:567-574.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 567-574
-
-
Soria, J.M.1
Almasy, L.2
Souto, J.C.3
Bacq, D.4
Buil, A.5
Faure, A.6
Martinez-Marchan, E.7
Mateo, J.8
Borrell, M.9
Stone, W.10
Lathrop, M.11
Fontcuberta, J.12
Blangero, J.13
-
41
-
-
0028322017
-
An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
-
Suzuki N, Cheung TT, Cai XD, Odaka A, Otvos L Jr, Eckman C, Golde TE, Younkin SG. 1994. An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants. Science 264:1336-1340.
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.D.3
Odaka, A.4
Otvos Jr., L.5
Eckman, C.6
Golde, T.E.7
Younkin, S.G.8
-
42
-
-
18544410708
-
The plasmin system is induced by and degrades amyloid-beta aggregates
-
Tucker HM, Kihiko M, Caldwell JN, Wright S, Kawarabayashi T, Price D, Walker D, Scheff S, McGillis JP, Rydel RE, Estus S. 2000. The plasmin system is induced by and degrades amyloid-beta aggregates. J Neurosci 20:3937-3946.
-
(2000)
J Neurosci
, vol.20
, pp. 3937-3946
-
-
Tucker, H.M.1
Kihiko, M.2
Caldwell, J.N.3
Wright, S.4
Kawarabayashi, T.5
Price, D.6
Walker, D.7
Scheff, S.8
McGillis, J.P.9
Rydel, R.E.10
Estus, S.11
-
43
-
-
0034161516
-
Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme
-
Vekrellis K, Ye Z, Qiu WQ, Walsh D, Hartley D, Chesneau V, Rosner MR, Selkoe DJ. 2000. Neurons regulate extracellular levels of amyloid beta-protein via proteolysis by insulin-degrading enzyme. J Neurosci 20:1657-1665.
-
(2000)
J Neurosci
, vol.20
, pp. 1657-1665
-
-
Vekrellis, K.1
Ye, Z.2
Qiu, W.Q.3
Walsh, D.4
Hartley, D.5
Chesneau, V.6
Rosner, M.R.7
Selkoe, D.J.8
-
44
-
-
0029062606
-
Computer programs for multilocus haplotyping of general pedigrees
-
Weeks DE, Sobel E, O'Connell JR, Lange K. 1995. Computer programs for multilocus haplotyping of general pedigrees. Am J Hum Genet 56:1506-1507.
-
(1995)
Am J Hum Genet
, vol.56
, pp. 1506-1507
-
-
Weeks, D.E.1
Sobel, E.2
O'Connell, J.R.3
Lange, K.4
|