-
1
-
-
33746450466
-
Chemotherapy resistance in osteosarcoma: Current challenges and future directions
-
Chou AJ and Gorlick R: Chemotherapy resistance in osteosarcoma: current challenges and future directions. Expert Rev Anticancer There 6: 1075-1085, 2006.
-
(2006)
Expert Rev Anticancer There
, vol.6
, pp. 1075-1085
-
-
Chou, A.J.1
Gorlick, R.2
-
2
-
-
33748156545
-
Primary bone osteosarcoma in the pediatric age: State of the art
-
Longhi A, Errani C, De Paolis M, Mercuri M and Bacci G: Primary bone osteosarcoma in the pediatric age: state of the art. Cancer Treat Rev 32: 423-436, 2006.
-
(2006)
Cancer Treat Rev
, vol.32
, pp. 423-436
-
-
Longhi, A.1
Errani, C.2
de Paolis, M.3
Mercuri, M.4
Bacci, G.5
-
3
-
-
50649107280
-
Therapy for osteosarcoma: Where do we go from here?
-
Chou AJ, Geller DS and Gorlick R: Therapy for osteosarcoma: where do we go from here? Paediatr Drugs 10: 315-327, 2008.
-
(2008)
Paediatr Drugs
, vol.10
, pp. 315-327
-
-
Chou, A.J.1
Geller, D.S.2
Gorlick, R.3
-
4
-
-
0024427025
-
Adjuvant chemotherapy for osteosarcoma
-
Eilber FR and Rosen G: Adjuvant chemotherapy for osteosarcoma. Semin Oncol 16: 312-322, 1989.
-
(1989)
Semin Oncol
, vol.16
, pp. 312-322
-
-
Eilber, F.R.1
Rosen, G.2
-
5
-
-
54049089246
-
Current status and perspectives regarding the treatment of osteo-sarcoma: Chemotherapy
-
Sakamoto A and Iwamoto Y: Current status and perspectives regarding the treatment of osteo-sarcoma: chemotherapy: Rev Recent Clin Trials 3: 228-231, 2008.
-
(2008)
Rev Recent Clin Trials
, vol.3
, pp. 228-231
-
-
Sakamoto, A.1
Iwamoto, Y.2
-
6
-
-
0027351189
-
Karnofsky memorial lecture. Ode to methotrexate
-
Bertino JR: Karnofsky memorial lecture. Ode to methotrexate. J Clin Oncol 11: 5-14, 1993.
-
(1993)
J Clin Oncol
, vol.11
, pp. 5-14
-
-
Bertino, J.R.1
-
7
-
-
12444266802
-
Genomic imbalances associated with methotrexate resistance in human osteosarcoma cell lines detected by comparative genomic hybridization-based techniques
-
Hattinger CM, Reverter-Branchat G, Remondini D, et al: Genomic imbalances associated with methotrexate resistance in human osteosarcoma cell lines detected by comparative genomic hybridization-based techniques. Eur J Cell Biol 82: 483-493, 2003.
-
(2003)
Eur J Cell Biol
, vol.82
, pp. 483-493
-
-
Hattinger, C.M.1
Reverter-Branchat, G.2
Remondini, D.3
-
8
-
-
0033001234
-
Mechanisms of methotrexate resistance in osteosarcoma
-
Guo W, Healey JH, Meyers PA, Ladanyi M, Huvos AG, Bertino JR and Gorlick R: Mechanisms of methotrexate resistance in osteosarcoma. Clin Cancer Res 5: 621-627, 1999.
-
(1999)
Clin Cancer Res
, vol.5
, pp. 621-627
-
-
Guo, W.1
Healey, J.H.2
Meyers, P.A.3
Ladanyi, M.4
Huvos, A.G.5
Bertino, J.R.6
Gorlick, R.7
-
9
-
-
64149090965
-
Methotrexate in pediatric osteosarcoma: Response and toxicity in relation to genetic polymorphisms and dihydrofolate reductase and reduced folate carrier 1 expression
-
Patiño-García A, Zalacaín M, Marrodán L, San-Julián M and Sierrasesúmaga L: Methotrexate in pediatric osteosarcoma: response and toxicity in relation to genetic polymorphisms and dihydrofolate reductase and reduced folate carrier 1 expression. J Pediatr 154: 688-693, 2009.
-
(2009)
J Pediatr
, vol.154
, pp. 688-693
-
-
Patiño-García, A.1
Zalacaín, M.2
Marrodán, L.3
San-Julián, M.4
Sierrasesúmaga, L.5
-
10
-
-
0142150087
-
Reduced folate carrier protein expression in osteosarcoma: Implications for the prediction of tumor chemosensitivity
-
Ifergan I, Meller I, Issakov J and Assaraf YG: Reduced folate carrier protein expression in osteosarcoma: implications for the prediction of tumor chemosensitivity. Cancer 98: 1958-1966, 2003.
-
(2003)
Cancer
, vol.98
, pp. 1958-1966
-
-
Ifergan, I.1
Meller, I.2
Issakov, J.3
Assaraf, Y.G.4
-
11
-
-
4644251592
-
Functional analysis of altered reduced folate carrier sequence changes identified in osteosarcomas
-
Flintoff WF, Sadlish H, Gorlick R, Yang R and Williams FM: Functional analysis of altered reduced folate carrier sequence changes identified in osteosarcomas. Biochim Biophys Acta 1690: 110-117, 2004.
-
(2004)
Biochim Biophys Acta
, vol.1690
, pp. 110-117
-
-
Flintoff, W.F.1
Sadlish, H.2
Gorlick, R.3
Yang, R.4
Williams, F.M.5
-
12
-
-
9144254448
-
Analysis of dihydrofolate reductase and reduced folate carrier gene status in relation to methotrexate resistance in osteosarcoma cells
-
Serra M, Reverter-Branchat G, Maurici D, et al: Analysis of dihydrofolate reductase and reduced folate carrier gene status in relation to methotrexate resistance in osteosarcoma cells. Ann Oncol 15: 151-160, 2004.
-
(2004)
Ann Oncol
, vol.15
, pp. 151-160
-
-
Serra, M.1
Reverter-Branchat, G.2
Maurici, D.3
-
13
-
-
0037317006
-
Sequence alterations in the reduced folate carrier are observed in osteosarcoma tumor samples
-
Yang R, Sowers R, Mazza BA, et al: Sequence alterations in the reduced folate carrier are observed in osteosarcoma tumor samples. Clin Cancer Res 9: 837-844, 2003.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 837-844
-
-
Yang, R.1
Sowers, R.2
Mazza, B.A.3
-
14
-
-
84872354932
-
High dose trimetrexate with leucovorin protection in recurrent childhood malignancies: A phase II trial
-
Trippett T, Meyers P, Gorlick R, et al: High dose trimetrexate with leucovorin protection in recurrent childhood malignancies: a phase II trial. J Clin Oncol (ASCO Annual Meeting Abstracts): 9: 889, 1999.
-
(1999)
J Clin Oncol (ASCO Annual Meeting Abstracts)
, vol.9
, pp. 889
-
-
Trippett, T.1
Meyers, P.2
Gorlick, R.3
-
15
-
-
0025176784
-
P-glycoproteins in pathology: The multidrug resistance gene family in humans
-
Weinstein RS, Kuszak JR, Kluskens LF and Coon JS: P-glycoproteins in pathology: the multidrug resistance gene family in humans. Hum Pathol 21: 34-48, 1990.
-
(1990)
Hum Pathol
, vol.21
, pp. 34-48
-
-
Weinstein, R.S.1
Kuszak, J.R.2
Kluskens, L.F.3
Coon, J.S.4
-
16
-
-
0025051429
-
Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185 Val-185 substitution in P-glycoprotein
-
Safa AR, Stern RK, Choi K, et al: Molecular basis of preferential resistance to colchicine in multidrug-resistant human cells conferred by Gly-185Val-185 substitution in P-glycoprotein. Proc Natl Acad Sci USA 87: 7225-7229, 1990.
-
(1990)
Proc Natl Acad Sci USA
, vol.87
, pp. 7225-7229
-
-
Safa, A.R.1
Stern, R.K.2
Choi, K.3
-
17
-
-
0034509426
-
Osteosarcomas and other cancers of bone
-
Bramwell VH: Osteosarcomas and other cancers of bone. Curr Opin Oncol 12: 330-336, 2000.
-
(2000)
Curr Opin Oncol
, vol.12
, pp. 330-336
-
-
Bramwell, V.H.1
-
18
-
-
0035110767
-
The co-expression of p53 protein and P-glycoprotein is correlated to a poor prognosis in osteosarcoma
-
Park YB, Kim HS, Oh JH and Lee SH: The co-expression of p53 protein and P-glycoprotein is correlated to a poor prognosis in osteosarcoma. Int Orthop 24: 307-310, 2001.
-
(2001)
Int Orthop
, vol.24
, pp. 307-310
-
-
Park, Y.B.1
Kim, H.S.2
Oh, J.H.3
Lee, S.H.4
-
19
-
-
33749426881
-
Multidrug resistance mediated by ABC transporters in osteosarcoma cell lines: MRNA analysis and functional radiotracer studies
-
Gomes CM, van Paassen H, Romeo S, et al: Multidrug resistance mediated by ABC transporters in osteosarcoma cell lines: mRNA analysis and functional radiotracer studies. Nucl Med Biol 33: 831-840, 2006.
-
(2006)
Nucl Med Biol
, vol.33
, pp. 831-840
-
-
Gomes, C.M.1
van Paassen, H.2
Romeo, S.3
-
20
-
-
36049026825
-
May P-glycoprotein status be used to stratify high-grade osteosarcoma patients? Results from the Italian/Scandinavian Sarcoma Group 1 treatment protocol
-
Serra M, Pasello M, Manara MC, et al: May P-glycoprotein status be used to stratify high-grade osteosarcoma patients? Results from the Italian/Scandinavian Sarcoma Group 1 treatment protocol. Int J Oncol 29: 1459-1468, 2006.
-
(2006)
Int J Oncol
, vol.29
, pp. 1459-1468
-
-
Serra, M.1
Pasello, M.2
Manara, M.C.3
-
21
-
-
0033197875
-
P-glycoprotein expression in osteosarcoma: A basis for risk-adapted adjuvant chemotherapy
-
Baldini N, Scotlandi K, Serra M, Picci P, Bacci G, Sottili S and Campanacci M: P-glycoprotein expression in osteosarcoma: a basis for risk-adapted adjuvant chemotherapy. J Orthop Res 17: 629-632, 1999.
-
(1999)
J Orthop Res
, vol.17
, pp. 629-632
-
-
Baldini, N.1
Scotlandi, K.2
Serra, M.3
Picci, P.4
Bacci, G.5
Sottili, S.6
Campanacci, M.7
-
22
-
-
0033606088
-
Relationship between P-glycoprotein positivity, doxorubicin binding ability and histologic response to chemotherapy in osteosarcomas
-
Kusuzaki K, Hirata M, Takeshita H, Murata H, Hashiguchi S, Ashihara T and Hirasawa Y: Relationship between P-glycoprotein positivity, doxorubicin binding ability and histologic response to chemotherapy in osteosarcomas. Cancer Lett 138: 203-208, 1999.
-
(1999)
Cancer Lett
, vol.138
, pp. 203-208
-
-
Kusuzaki, K.1
Hirata, M.2
Takeshita, H.3
Murata, H.4
Hashiguchi, S.5
Ashihara, T.6
Hirasawa, Y.7
-
23
-
-
0034190396
-
Multidrug resistance-1 gene expression does not increase during tumor progression in the MGH-OGS murine osteosarcoma tumor model
-
Trammell RA, Johnson CB, Barker JR, Bell RS and Allan DG: Multidrug resistance-1 gene expression does not increase during tumor progression in the MGH-OGS murine osteosarcoma tumor model. J Orthop Res 18: 449-455, 2000.
-
(2000)
J Orthop Res
, vol.18
, pp. 449-455
-
-
Trammell, R.A.1
Johnson, C.B.2
Barker, J.R.3
Bell, R.S.4
Allan, D.G.5
-
24
-
-
18744431612
-
MDR1 gene expression and outcome in osteosarcoma: A prospective, multicenter study
-
Wunder JS, Bull SB, Aneliunas V, et al: MDR1 gene expression and outcome in osteosarcoma: a prospective, multicenter study. J Clin Oncol 18: 2685-2694, 2000.
-
(2000)
J Clin Oncol
, vol.18
, pp. 2685-2694
-
-
Wunder, J.S.1
Bull, S.B.2
Aneliunas, V.3
-
25
-
-
0038298496
-
The association of P-glycoprotein with response to chemotherapy and clinical outcome in patients with osteosarcoma. A meta-analysis
-
Pakos EE and Ioannidis JP: The association of P-glycoprotein with response to chemotherapy and clinical outcome in patients with osteosarcoma. A meta-analysis. Cancer 98: 581-589, 2003.
-
(2003)
Cancer
, vol.98
, pp. 581-589
-
-
Pakos, E.E.1
Ioannidis, J.P.2
-
26
-
-
62549110360
-
Immunohistochemical estimates of angiogenesis, proliferative activity, p53 expression, and multiple drug resistance have no prognostic impact in osteosarcoma: A comparative clinicopathological investigation
-
Sorensen FB, Jensen K, Vaeth M, et al: Immunohistochemical estimates of angiogenesis, proliferative activity, p53 expression, and multiple drug resistance have no prognostic impact in osteosarcoma: A comparative clinicopathological investigation. Sarcoma 2008: 874075, 2008.
-
(2008)
Sarcoma
, pp. 874075
-
-
Sorensen, F.B.1
Jensen, K.2
Vaeth, M.3
-
27
-
-
0034060345
-
Osteoblastic differentiation and P-glycoprotein multidrug resistance in a murine osteosarcoma model
-
Takeshita H, Kusuzaki K, Murata H, et al: Osteoblastic differentiation and P-glycoprotein multidrug resistance in a murine osteosarcoma model. Br J Cancer 82: 1327-1331, 2000.
-
(2000)
Br J Cancer
, vol.82
, pp. 1327-1331
-
-
Takeshita, H.1
Kusuzaki, K.2
Murata, H.3
-
28
-
-
77956544799
-
Inhibition of ABCB1 (MDR1) expression by an siRNA nanoparticulate delivery system to overcome drug resistance in osteosarcoma
-
Susa M, Iyer AK, Ryu K, Choy E, Hornicek FJ, Mankin H, Milane L, Amiji MM and Duan Z: Inhibition of ABCB1 (MDR1) expression by an siRNA nanoparticulate delivery system to overcome drug resistance in osteosarcoma. PLoS One 5: e10764, 2010.
-
(2010)
PLoS One
, vol.5
-
-
Susa, M.1
Iyer, A.K.2
Ryu, K.3
Choy, E.4
Hornicek, F.J.5
Mankin, H.6
Milane, L.7
Amiji, M.M.8
Duan, Z.9
-
29
-
-
71949105972
-
Doxorubicin loaded polymeric nanoparticulate delivery system to overcome drug resistance in osteosarcoma
-
Susa M, Iyer AK, Ryu K, Hornicek FJ, Mankin H, Amiji MM and Duan Z: Doxorubicin loaded polymeric nanoparticulate delivery system to overcome drug resistance in osteosarcoma. BMC Cancer 9: 399, 2009.
-
(2009)
BMC Cancer
, vol.9
, pp. 399
-
-
Susa, M.1
Iyer, A.K.2
Ryu, K.3
Hornicek, F.J.4
Mankin, H.5
Amiji, M.M.6
Duan, Z.7
-
30
-
-
84875772283
-
Lipid-functionalized dextran nanosystems to overcome multidrug resistance in cancer: A pilot study
-
Kobayashi E, Iyer AK, Hornicek FJ, Amiji MM and Duan Z: Lipid-functionalized dextran nanosystems to overcome multidrug resistance in cancer: a pilot study. Clin Orthop Relat Res 471: 915-925, 2013.
-
(2013)
Clin Orthop Relat Res
, vol.471
, pp. 915-925
-
-
Kobayashi, E.1
Iyer, A.K.2
Hornicek, F.J.3
Amiji, M.M.4
Duan, Z.5
-
31
-
-
0642374221
-
The role of glutathione-S-transferase in anti-cancer drug resistance
-
Townsend DM and Tew KD: The role of glutathione-S-transferase in anti-cancer drug resistance. Oncogene 22: 7369-7375, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 7369-7375
-
-
Townsend, D.M.1
Tew, K.D.2
-
32
-
-
0028106016
-
Glutathione-associated enzymes in anticancer drug resistance
-
Tew KD: Glutathione-associated enzymes in anticancer drug resistance. Cancer Res 54: 4313-4320, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 4313-4320
-
-
Tew, K.D.1
-
33
-
-
0030895104
-
Detection and significance of glutathione-S-transferase pi in osteogenic tumors of dogs
-
Shoieb A and Hahn K: Detection and significance of glutathione-S-transferase pi in osteogenic tumors of dogs. Int J Oncol 10: 635-639, 1997.
-
(1997)
Int J Oncol
, vol.10
, pp. 635-639
-
-
Shoieb, A.1
Hahn, K.2
-
34
-
-
0030902367
-
Overexpression of resistance-related proteins (metallothioneins, glutathione-S-transferase pi, heat shock protein 27, and lung resistance-related protein) in osteosarcoma. Relationship with poor prognosis
-
Uozaki H, Horiuchi H, Ishida T, Iijima T, Imamura T and Machinami R: Overexpression of resistance-related proteins (metallothioneins, glutathione-S-transferase pi, heat shock protein 27, and lung resistance-related protein) in osteosarcoma. Relationship with poor prognosis. Cancer 79: 2336-2344, 1997.
-
(1997)
Cancer
, vol.79
, pp. 2336-2344
-
-
Uozaki, H.1
Horiuchi, H.2
Ishida, T.3
Iijima, T.4
Imamura, T.5
Machinami, R.6
-
35
-
-
38749131631
-
Expression of MDR1 and GST-pi in osteosarcoma and soft tissue sarcoma and their correlation with chemotherapy resistance
-
In Chinese
-
Wei L, Song XR, Wang XW, Li M and Zuo WS: Expression of MDR1 and GST-pi in osteosarcoma and soft tissue sarcoma and their correlation with chemotherapy resistance. Zhonghua Zhong Liu Za Zhi 28: 445-448, 2006 (In Chinese).
-
(2006)
Zhonghua Zhong Liu Za Zhi
, vol.28
, pp. 445-448
-
-
Wei, L.1
Song, X.R.2
Wang, X.W.3
Li, M.4
Zuo, W.S.5
-
36
-
-
7044226340
-
Human osteosarcoma xenografts and their sensitivity to chemotherapy
-
Bruheim S, Bruland OS, Breistol K, Maelandsmo GM and Fodstad O: Human osteosarcoma xenografts and their sensitivity to chemotherapy. Pathol Oncol Res 10: 133-141, 2004.
-
(2004)
Pathol Oncol Res
, vol.10
, pp. 133-141
-
-
Bruheim, S.1
Bruland, O.S.2
Breistol, K.3
Maelandsmo, G.M.4
Fodstad, O.5
-
37
-
-
34250757693
-
Expression of human glutathione S-transferase P1 mediates the chemosensitivity of osteosarcoma cells
-
Huang G, Mills L and Worth LL: Expression of human glutathione S-transferase P1 mediates the chemosensitivity of osteosarcoma cells. Mol Cancer Ther 6: 1610-1619, 2007.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1610-1619
-
-
Huang, G.1
Mills, L.2
Worth, L.L.3
-
38
-
-
84858706750
-
Germline genetic polymorphisms may influence chemotherapy response and disease outcome in osteosarcoma: A pilot study
-
Windsor RE, Strauss SJ, Kallis C, Wood NE and Whelan JS: Germline genetic polymorphisms may influence chemotherapy response and disease outcome in osteosarcoma: a pilot study. Cancer 118: 1856-1867, 2012.
-
(2012)
Cancer
, vol.118
, pp. 1856-1867
-
-
Windsor, R.E.1
Strauss, S.J.2
Kallis, C.3
Wood, N.E.4
Whelan, J.S.5
-
39
-
-
84874061870
-
Predictive potential of glutathione S-transferase polymorphisms for prognosis of osteosarcoma patients on chemotherapy
-
Zhang SL, Mao NF, Sun JY, Shi ZC, Wang B and Sun YJ: Predictive potential of glutathione S-transferase polymorphisms for prognosis of osteosarcoma patients on chemotherapy. Asian Pac J Cancer Prev 13: 2705-2709, 2012.
-
(2012)
Asian Pac J Cancer Prev
, vol.13
, pp. 2705-2709
-
-
Zhang, S.L.1
Mao, N.F.2
Sun, J.Y.3
Shi, Z.C.4
Wang, B.5
Sun, Y.J.6
-
40
-
-
84874024558
-
Glutathione S-transferase P1 and DNA polymorphisms influence response to chemotherapy and prognosis of bone tumors
-
Yang LM, Li XH and Bao CF: Glutathione S-transferase P1 and DNA polymorphisms influence response to chemotherapy and prognosis of bone tumors. Asian Pac J Cancer Prev 13: 5883-5886, 2012.
-
(2012)
Asian Pac J Cancer Prev
, vol.13
, pp. 5883-5886
-
-
Yang, L.M.1
Li, X.H.2
Bao, C.F.3
-
41
-
-
53049088957
-
Overcoming glutathione S-transferase P1-related cisplatin resistance in osteosarcoma
-
Pasello M, Michelacci F, Scionti I, Hattinger CM, Zuntini M, Caccuri AM, Scotlandi K, Picci P and Serra M: Overcoming glutathione S-transferase P1-related cisplatin resistance in osteosarcoma. Cancer Res 68: 6661-6668, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 6661-6668
-
-
Pasello, M.1
Michelacci, F.2
Scionti, I.3
Hattinger, C.M.4
Zuntini, M.5
Caccuri, A.M.6
Scotlandi, K.7
Picci, P.8
Serra, M.9
-
42
-
-
79960809400
-
Targeting glutathione-S transferase enzymes in musculoskeletal sarcomas: A promising therapeutic strategy
-
Pasello M, Manara MC, Michelacci F, et al: Targeting glutathione-S transferase enzymes in musculoskeletal sarcomas: a promising therapeutic strategy. Anal Cell Pathol (Amst) 34: 131-145, 2011.
-
(2011)
Anal Cell Pathol (Amst)
, vol.34
, pp. 131-145
-
-
Pasello, M.1
Manara, M.C.2
Michelacci, F.3
-
43
-
-
84858011803
-
Targeting GSTP1-1 induces JNK activation and leads to apoptosis in cisplatin-sensitive and -resistant human osteosarcoma cell lines
-
Sau A, Filomeni G, Pezzola S, et al: Targeting GSTP1-1 induces JNK activation and leads to apoptosis in cisplatin-sensitive and -resistant human osteosarcoma cell lines. Mol Biosyst 8: 994-1006, 2012.
-
(2012)
Mol Biosyst
, vol.8
, pp. 994-1006
-
-
Sau, A.1
Filomeni, G.2
Pezzola, S.3
-
44
-
-
24344451212
-
APE1 and XRCC1 protein expression levels predict cancer-specific survival following radical radiotherapy in bladder cancer
-
Sak SC, Harnden P, Johnston CF, Paul AB and Kiltie AE: APE1 and XRCC1 protein expression levels predict cancer-specific survival following radical radiotherapy in bladder cancer. Clin Cancer Res 11: 6205-6211, 2005.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 6205-6211
-
-
Sak, S.C.1
Harnden, P.2
Johnston, C.F.3
Paul, A.B.4
Kiltie, A.E.5
-
46
-
-
0036718792
-
The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress
-
Silber JR, Bobola MS, Blank A, Schoeler KD, Haroldson PD, Huynh MB and Kolstoe DD: The apurinic/apyrimidinic endonuclease activity of Ape1/Ref-1 contributes to human glioma cell resistance to alkylating agents and is elevated by oxidative stress. Clin Cancer Res 8: 3008-3018, 2002.
-
(2002)
Clin Cancer Res
, vol.8
, pp. 3008-3018
-
-
Silber, J.R.1
Bobola, M.S.2
Blank, A.3
Schoeler, K.D.4
Haroldson, P.D.5
Huynh, M.B.6
Kolstoe, D.D.7
-
47
-
-
30344434348
-
Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (Ape/Ref-1) in human melanoma and identification of the therapeutic potential of resveratrol as an Ape1/Ref-1 inhibitor
-
Yang S, Irani K, Heffron SE, Jurnak F and Meyskens FL Jr: Alterations in the expression of the apurinic/apyrimidinic endonuclease-1/redox factor-1 (Ape/Ref-1) in human melanoma and identification of the therapeutic potential of resveratrol as an Ape1/Ref-1 inhibitor. Mol Cancer Ther 4: 1923-1935, 2005.
-
(2005)
Mol Cancer Ther
, vol.4
, pp. 1923-1935
-
-
Yang, S.1
Irani, K.2
Heffron, S.E.3
Jurnak, F.4
Meyskens Jr., F.L.5
-
48
-
-
4444327784
-
Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: Enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition
-
Wang D, Luo M and Kelley MR: Human apurinic endonuclease 1 (APE1) expression and prognostic significance in osteosarcoma: enhanced sensitivity of osteosarcoma to DNA damaging agents using silencing RNA APE1 expression inhibition. Mol Cancer Ther 3: 679-686, 2004.
-
(2004)
Mol Cancer Ther
, vol.3
, pp. 679-686
-
-
Wang, D.1
Luo, M.2
Kelley, M.R.3
-
49
-
-
35548948785
-
Vector-based Ape1 small interfering RNA enhances the sensitivity of human osteosarcoma cells to endostatin in vivo
-
Wang D, Zhong ZY, Li MX, Xiang DB and Li ZP: Vector-based Ape1 small interfering RNA enhances the sensitivity of human osteosarcoma cells to endostatin in vivo. Cancer Sci 98: 1993-2001, 2007.
-
(2007)
Cancer Sci
, vol.98
, pp. 1993-2001
-
-
Wang, D.1
Zhong, Z.Y.2
Li, M.X.3
Xiang, D.B.4
Li, Z.P.5
-
50
-
-
77952062040
-
APEX1 gene amplification and its protein overexpression in osteosarcoma: Correlation with recurrence, metastasis, and survival
-
Yang JL, Yang D, Cogdell D, et al: APEX1 gene amplification and its protein overexpression in osteosarcoma: correlation with recurrence, metastasis, and survival. Technol Cancer Res Treat 9: 161-169, 2010.
-
(2010)
Technol Cancer Res Treat
, vol.9
, pp. 161-169
-
-
Yang, J.L.1
Yang, D.2
Cogdell, D.3
-
51
-
-
4444336712
-
Inhibition of the human apurinic/apyrimidinic endonuclease (APE1) repair activity and sensitization of breast cancer cells to DNA alkylating agents with lucanthone
-
Luo M and Kelley MR: Inhibition of the human apurinic/apyrimidinic endonuclease (APE1) repair activity and sensitization of breast cancer cells to DNA alkylating agents with lucanthone. Anticancer Res 24: 2127-2134, 2004.
-
(2004)
Anticancer Res
, vol.24
, pp. 2127-2134
-
-
Luo, M.1
Kelley, M.R.2
-
52
-
-
24044516224
-
Isolation of a small molecule inhibitor of base excision repair
-
Madhusudan S, Smart F, Shrimpton P, et al: Isolation of a small molecule inhibitor of base excision repair. Nucleic Acids Res 33: 4711-4724, 2005.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 4711-4724
-
-
Madhusudan, S.1
Smart, F.2
Shrimpton, P.3
-
53
-
-
40849135868
-
Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids
-
Seiple LA, Cardellina JH II, Akee R and Stivers JT: Potent inhibition of human apurinic/apyrimidinic endonuclease 1 by arylstibonic acids. Mol Pharmacol 73: 669-677, 2008.
-
(2008)
Mol Pharmacol
, vol.73
, pp. 669-677
-
-
Seiple, L.A.1
Cardellina, J.H.I.I.2
Akee, R.3
Stivers, J.T.4
-
54
-
-
34548276529
-
The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target
-
Fishel ML and Kelley MR: The DNA base excision repair protein Ape1/Ref-1 as a therapeutic and chemopreventive target. Mol Aspects Med 28: 375-395, 2007.
-
(2007)
Mol Aspects Med
, vol.28
, pp. 375-395
-
-
Fishel, M.L.1
Kelley, M.R.2
-
55
-
-
2242484585
-
Expression of genes of potential importance in the response to chemotherapy in osteosarcoma patients
-
In German
-
Nathrath M, Kremer M, Letzel H, Remberger K, Höfler H and Ulle T: Expression of genes of potential importance in the response to chemotherapy in osteosarcoma patients. Klin Padiatr 214: 230-235, 2002 (In German).
-
(2002)
Klin Padiatr
, vol.214
, pp. 230-235
-
-
Nathrath, M.1
Kremer, M.2
Letzel, H.3
Remberger, K.4
Höfler, H.5
Ulle, T.6
-
56
-
-
77955661262
-
Expressions of ERCC2 and ERCC4 genes in osteosarcoma and peripheral blood lymphocytes and their clinical significance
-
In Chinese
-
Li X, Guo W, Shen DH, Yang RL, Liu J and Zhao H: Expressions of ERCC2 and ERCC4 genes in osteosarcoma and peripheral blood lymphocytes and their clinical significance. Beijing Da Xue Xue Bao 39: 467-471, 2007 (In Chinese).
-
(2007)
Beijing Da Xue Xue Bao
, vol.39
, pp. 467-471
-
-
Li, X.1
Guo, W.2
Shen, D.H.3
Yang, R.L.4
Liu, J.5
Zhao, H.6
-
57
-
-
70349678400
-
Common variations in ERCC2 are associated with response to cisplatin chemotherapy and clinical outcome in osteosarcoma patients
-
Caronia D, Patiño-García A, Milne RL, Zalacain-Díez M, Pita G, Alonso MR, Moreno LT, et al: Common variations in ERCC2 are associated with response to cisplatin chemotherapy and clinical outcome in osteosarcoma patients. Pharmacogenomics J 9: 347-353, 2009.
-
(2009)
Pharmacogenomics J
, vol.9
, pp. 347-353
-
-
Caronia, D.1
Patiño-García, A.2
Milne, R.L.3
Zalacain-Díez, M.4
Pita, G.5
Alonso, M.R.6
Moreno, L.T.7
-
58
-
-
84870055970
-
Nucleotide excision repair gene variants and association with survival in osteosarcoma patients treated with neoadjuvant chemotherapy
-
Biason P, Hattinger CM, Innocenti F, Talamini R, Alberghini M, Scotlandi K, Zanusso C, Serra M and Toffoli G: Nucleotide excision repair gene variants and association with survival in osteosarcoma patients treated with neoadjuvant chemotherapy. Pharmacogenomics J 12: 476-483, 2012.
-
(2012)
Pharmacogenomics J
, vol.12
, pp. 476-483
-
-
Biason, P.1
Hattinger, C.M.2
Innocenti, F.3
Talamini, R.4
Alberghini, M.5
Scotlandi, K.6
Zanusso, C.7
Serra, M.8
Toffoli, G.9
-
59
-
-
84873614801
-
Association of four ERCC1 and ERCC2 SNPs with survival of bone tumour patients
-
Hao T, Feng W, Zhang J, Sun YJ and Wang G: Association of four ERCC1 and ERCC2 SNPs with survival of bone tumour patients. Asian Pac J Cancer Prev 13: 3821-3824, 2012.
-
(2012)
Asian Pac J Cancer Prev
, vol.13
, pp. 3821-3824
-
-
Hao, T.1
Feng, W.2
Zhang, J.3
Sun, Y.J.4
Wang, G.5
-
60
-
-
65549167833
-
Targeting the mTOR signaling network for cancer therapy
-
Meric-Bernstam F and Gonzalez-Angulo AM: Targeting the mTOR signaling network for cancer therapy. J Clin Oncol 27: 2278-2287, 2009.
-
(2009)
J Clin Oncol
, vol.27
, pp. 2278-2287
-
-
Meric-Bernstam, F.1
Gonzalez-Angulo, A.M.2
-
61
-
-
49749093760
-
Evaluation of the mammalian target of rapamycin pathway and the effect of rapamycin on target expression and cellular proliferation in osteosarcoma cells from dogs
-
Gordon IK, Ye F and Kent MS: Evaluation of the mammalian target of rapamycin pathway and the effect of rapamycin on target expression and cellular proliferation in osteosarcoma cells from dogs. Am J Vet Res 69: 1079-1084, 2008.
-
(2008)
Am J Vet Res
, vol.69
, pp. 1079-1084
-
-
Gordon, I.K.1
Ye, F.2
Kent, M.S.3
-
62
-
-
64549109015
-
Targeted therapy of human osteosarcoma with 17AAG or rapamycin: Characterization of induced apoptosis and inhibition of mTOR and Akt/MAPK/Wnt pathways
-
Gazitt Y, Kolapathi V, Moncada K, Thomas C and Freeman J: Targeted therapy of human osteosarcoma with 17AAG or rapamycin: characterization of induced apoptosis and inhibition of mTOR and Akt/MAPK/Wnt pathways. Int J Oncol 34: 551-561, 2009.
-
(2009)
Int J Oncol
, vol.34
, pp. 551-561
-
-
Gazitt, Y.1
Kolapathi, V.2
Moncada, K.3
Thomas, C.4
Freeman, J.5
-
63
-
-
78650322560
-
mTOR/p70S6K signal transduction pathway contributes to osteosarcoma progression and patients' prognosis
-
Zhou Q, Deng Z, Zhu Y, Long H, Zhang S and Zhao J: mTOR/p70S6K signal transduction pathway contributes to osteosarcoma progression and patients' prognosis. Med Oncol 27: 1239-1245, 2010.
-
(2010)
Med Oncol
, vol.27
, pp. 1239-1245
-
-
Zhou, Q.1
Deng, Z.2
Zhu, Y.3
Long, H.4
Zhang, S.5
Zhao, J.6
-
64
-
-
40449091406
-
Initial testing (stage 1) of the mTOR inhibitor rapamycin by the pediatric preclinical testing program
-
Houghton PJ, Morton CL, Kolb EA, et al: Initial testing (stage 1) of the mTOR inhibitor rapamycin by the pediatric preclinical testing program. Pediatr Blood Cancer 50: 799-805, 2008.
-
(2008)
Pediatr Blood Cancer
, vol.50
, pp. 799-805
-
-
Houghton, P.J.1
Morton, C.L.2
Kolb, E.A.3
-
65
-
-
16844366544
-
Rapamycin inhibits ezrin-mediated metastatic behavior in a murine model of osteosarcoma
-
Wan X, Mendoza A, Khanna C and Helman LJ: Rapamycin inhibits ezrin-mediated metastatic behavior in a murine model of osteosarcoma. Cancer Res 65: 2406-2411, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 2406-2411
-
-
Wan, X.1
Mendoza, A.2
Khanna, C.3
Helman, L.J.4
-
66
-
-
84890039721
-
Rapamycin inhibits ALDH activity, resistance to oxidative stress, and metastatic potential in murine osteosarcoma cells
-
Mu X, Isaac C, Schott T, Huard J and Weiss K: Rapamycin inhibits ALDH activity, resistance to oxidative stress, and metastatic potential in murine osteosarcoma cells. Sarcoma 2013: 480713, 2013.
-
(2013)
Sarcoma 2013
, pp. 480713
-
-
Mu, X.1
Isaac, C.2
Schott, T.3
Huard, J.4
Weiss, K.5
-
67
-
-
0038398622
-
The insulin-like growth factor system and cancer
-
LeRoith D and Roberts CT Jr: The insulin-like growth factor system and cancer. Cancer Lett 195: 127-137, 2003.
-
(2003)
Cancer Lett
, vol.195
, pp. 127-137
-
-
Leroith, D.1
Roberts Jr., C.T.2
-
68
-
-
56749110996
-
The type 1 insulin-like growth factor receptor pathway
-
Chitnis MM, Yuen JS, Protheroe AS, Pollak M and Macaulay VM: The type 1 insulin-like growth factor receptor pathway. Clin Cancer Res 14: 6364-6370, 2008.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 6364-6370
-
-
Chitnis, M.M.1
Yuen, J.S.2
Protheroe, A.S.3
Pollak, M.4
Macaulay, V.M.5
-
69
-
-
84896272413
-
Analysis of aberrant signal transduction pathways in osteosarcoma cell lines
-
Chou AJ, Merola PR, Sowers R, et al: Analysis of aberrant signal transduction pathways in osteosarcoma cell lines. Proc Amer Assoc Cancer Res 46: 4551, 2005.
-
(2005)
Proc Amer Assoc Cancer Res
, vol.46
, pp. 4551
-
-
Chou, A.J.1
Merola, P.R.2
Sowers, R.3
-
70
-
-
20944447905
-
Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors
-
Scotlandi K, Manara MC, Nicoletti G, et al: Antitumor activity of the insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 in musculoskeletal tumors. Cancer Res 65: 3868-3876, 2005.
-
(2005)
Cancer Res
, vol.65
, pp. 3868-3876
-
-
Scotlandi, K.1
Manara, M.C.2
Nicoletti, G.3
-
71
-
-
33845313289
-
Down-regulation of insulin-like growth factor I receptor activity by NVP-AEW541 has an antitumor effect on neuroblastoma cells in vitro and in vivo
-
Tanno B, Mancini C, Vitali R, et al: Down-regulation of insulin-like growth factor I receptor activity by NVP-AEW541 has an antitumor effect on neuroblastoma cells in vitro and in vivo. Clin Cancer Res 12: 6772-6780, 2006.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6772-6780
-
-
Tanno, B.1
Mancini, C.2
Vitali, R.3
-
72
-
-
84856220447
-
Cell surface receptor expression patterns in osteosarcoma
-
Hassan SE, Bekarev M, Kim MY, Lin J, Piperdi S, Gorlick R and Geller DS: Cell surface receptor expression patterns in osteosarcoma. Cancer 118: 740-749, 2012.
-
(2012)
Cancer
, vol.118
, pp. 740-749
-
-
Hassan, S.E.1
Bekarev, M.2
Kim, M.Y.3
Lin, J.4
Piperdi, S.5
Gorlick, R.6
Geller, D.S.7
-
73
-
-
80052702630
-
IGF1R-targeted therapy and its enhancement of doxorubicin chemosensitivity in human osteosarcoma cell lines
-
Luk F, Yu Y, Walsh WR and Yang JL: IGF1R-targeted therapy and its enhancement of doxorubicin chemosensitivity in human osteosarcoma cell lines. Cancer Invest 29: 521-532, 2011.
-
(2011)
Cancer Invest
, vol.29
, pp. 521-532
-
-
Luk, F.1
Yu, Y.2
Walsh, W.R.3
Yang, J.L.4
-
74
-
-
77955013854
-
Lentivirus-mediated shRNA targeting insulin-like growth factor-1 receptor (IGF-1R) enhances chemosensitivity of osteosarcoma cells in vitro and in vivo
-
Wang YH, Xiong J, Wang SF, Yu Y, Wang B, Chen YX, Shi HF and Qiu Y: Lentivirus-mediated shRNA targeting insulin-like growth factor-1 receptor (IGF-1R) enhances chemosensitivity of osteosarcoma cells in vitro and in vivo. Mol Cell Biochem 341: 225-233, 2010.
-
(2010)
Mol Cell Biochem
, vol.341
, pp. 225-233
-
-
Wang, Y.H.1
Xiong, J.2
Wang, S.F.3
Yu, Y.4
Wang, B.5
Chen, Y.X.6
Shi, H.F.7
Qiu, Y.8
-
75
-
-
84882428581
-
Multiple receptor tyrosine kinases promote the in vitro phenotype of metastatic human osteosarcoma cell lines
-
Rettew AN, Young ED, Lev DC, Kleinerman ES, Abdul-Karim FW, Getty PJ and Greenfield EM: Multiple receptor tyrosine kinases promote the in vitro phenotype of metastatic human osteosarcoma cell lines. Oncogenesis 1: e34, 2012.
-
(2012)
Oncogenesis
, vol.1
-
-
Rettew, A.N.1
Young, E.D.2
Lev, D.C.3
Kleinerman, E.S.4
Abdul-Karim, F.W.5
Getty, P.J.6
Greenfield, E.M.7
-
76
-
-
84860389568
-
Increased expression of insulin-like growth factor-1 receptor is correlated with tumor metastasis and prognosis in patients with osteosarcoma
-
Wang YH, Han XD, Qiu Y, et al: Increased expression of insulin-like growth factor-1 receptor is correlated with tumor metastasis and prognosis in patients with osteosarcoma. J Surg Oncol 105: 235-243, 2012.
-
(2012)
J Surg Oncol
, vol.105
, pp. 235-243
-
-
Wang, Y.H.1
Han, X.D.2
Qiu, Y.3
-
77
-
-
84875543855
-
Clinical development of insulin-like growth factor receptor-1 (IGF-1R) inhibitors: At the crossroad?
-
Gombos A, Metzger-Filho O, Dal Lago L and Awada-Hussein A: Clinical development of insulin-like growth factor receptor-1 (IGF-1R) inhibitors: at the crossroad? Invest New Drugs 30: 2433-2442, 2012.
-
(2012)
Invest New Drugs
, vol.30
, pp. 2433-2442
-
-
Gombos, A.1
Metzger-Filho, O.2
Dal Lago, L.3
Awada-Hussein, A.4
-
78
-
-
78650750911
-
AMG 479 in relapsed or refractory Ewing's family tumors (EFT) or desmoplastic small round cell tumors (DSRCT): Phase II results
-
Tap WD, Demetri GD, Barnette P, et al: AMG 479 in relapsed or refractory Ewing's family tumors (EFT) or desmoplastic small round cell tumors (DSRCT): Phase II results. J Clin Oncol 28: (15 Suppl), 10001, 2010.
-
(2010)
J Clin Oncol
, vol.28
, Issue.15 SUPPL.
, pp. 10001
-
-
Tap, W.D.1
Demetri, G.D.2
Barnette, P.3
-
79
-
-
84896306368
-
-
Natinoal Institutes of Health: A Study to Determine the Activity of SCH 717454 in Subjects with Relapsed Osteosarcoma or Ewing's Sarcoma (Study P04720AM3), Accessed April 6, 2011
-
Natinoal Institutes of Health: A Study to Determine the Activity of SCH 717454 in Subjects with Relapsed Osteosarcoma or Ewing's Sarcoma (Study P04720AM3). http://clinicaltrials.gov/ct2/show/NCT00617890?term=sch-717454&rank=2. Accessed April 6, 2011.
-
-
-
-
80
-
-
0036500022
-
ErbB2 expression is correlated with increased survival of patients with osteosarcoma
-
Akatsuka T, Wada T, Kokai Y, et al: ErbB2 expression is correlated with increased survival of patients with osteosarcoma. Cancer 94: 1397-1404, 2002.
-
(2002)
Cancer
, vol.94
, pp. 1397-1404
-
-
Akatsuka, T.1
Wada, T.2
Kokai, Y.3
-
81
-
-
78650847136
-
VEGF and EMMPRIN expression correlates with survival of patients with osteosarcoma
-
Zhou Q, Zhu Y, Deng Z, Long H, Zhang S and Chen X: VEGF and EMMPRIN expression correlates with survival of patients with osteosarcoma. Surg Oncol 20: 13-19, 2011.
-
(2011)
Surg Oncol
, vol.20
, pp. 13-19
-
-
Zhou, Q.1
Zhu, Y.2
Deng, Z.3
Long, H.4
Zhang, S.5
Chen, X.6
-
82
-
-
38549164180
-
Initial testing of the VEGFR inhibitor AZD2171 by the pediatric preclinical testing program
-
Maris JM, Courtright J, Houghton PJ, et al: Initial testing of the VEGFR inhibitor AZD2171 by the pediatric preclinical testing program. Pediatr Blood Cancer 50: 581-587, 2008.
-
(2008)
Pediatr Blood Cancer
, vol.50
, pp. 581-587
-
-
Maris, J.M.1
Courtright, J.2
Houghton, P.J.3
-
83
-
-
84864044404
-
Phase II trial of trastuzumab in combination with cytotoxic chemotherapy for treatment of metastatic osteosarcoma with human epidermal growth factor receptor 2 overexpression: A report from the children's oncology group
-
Ebb D, Meyers P, Grier H, et al: Phase II trial of trastuzumab in combination with cytotoxic chemotherapy for treatment of metastatic osteosarcoma with human epidermal growth factor receptor 2 overexpression: a report from the children's oncology group. J Clin Oncol 30: 2545-2551, 2012.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2545-2551
-
-
Ebb, D.1
Meyers, P.2
Grier, H.3
-
84
-
-
0029097316
-
Molecular controls of growth arrest and apoptosis: P53-dependent and independent pathways
-
Liebermann DA, Hoffman B and Steinman RA: Molecular controls of growth arrest and apoptosis: p53-dependent and independent pathways. Oncogene 11: 199-210, 1995.
-
(1995)
Oncogene
, vol.11
, pp. 199-210
-
-
Liebermann, D.A.1
Hoffman, B.2
Steinman, R.A.3
-
85
-
-
0033368192
-
De novo deletions of p53 gene and wild-type p53 correlate with acquired cisplatin-resistance in human osteosarcoma OST cell line
-
Asada N, Tsuchiya H and Tomita K: De novo deletions of p53 gene and wild-type p53 correlate with acquired cisplatin-resistance in human osteosarcoma OST cell line. Anticancer Res 19: 5131-5137, 1999.
-
(1999)
Anticancer Res
, vol.19
, pp. 5131-5137
-
-
Asada, N.1
Tsuchiya, H.2
Tomita, K.3
-
86
-
-
34147172345
-
p53-R273H gains new function in induction of drug resistance through down-regulation of procaspase-3
-
Wong RP, Tsang WP, Chau PY, Co NN, Tsang TY and Kwok TT: p53-R273H gains new function in induction of drug resistance through down-regulation of procaspase-3. Mol Cancer Ther 6: 1054-1061, 2007.
-
(2007)
Mol Cancer Ther
, vol.6
, pp. 1054-1061
-
-
Wong, R.P.1
Tsang, W.P.2
Chau, P.Y.3
Co, N.N.4
Tsang, T.Y.5
Kwok, T.T.6
-
87
-
-
0032749714
-
Modulation of cisplatinum cytotoxicity by p53: Effect of p53-mediated apoptosis and DNA repair
-
Fan J and Bertino JR: Modulation of cisplatinum cytotoxicity by p53: effect of p53-mediated apoptosis and DNA repair. Mol Pharmacol 56: 966-972, 1999.
-
(1999)
Mol Pharmacol
, vol.56
, pp. 966-972
-
-
Fan, J.1
Bertino, J.R.2
-
88
-
-
0034073148
-
Sensitization and caffeine potentiation of cisplatin cytotoxicity resulting from introduction of wild-type p53 gene in human osteosarcoma
-
Tsuchiya H, Mori Y, Ueda Y, Okada G and Tomita K: Sensitization and caffeine potentiation of cisplatin cytotoxicity resulting from introduction of wild-type p53 gene in human osteosarcoma. Anticancer Res 20: 235-242, 2000.
-
(2000)
Anticancer Res
, vol.20
, pp. 235-242
-
-
Tsuchiya, H.1
Mori, Y.2
Ueda, Y.3
Okada, G.4
Tomita, K.5
-
89
-
-
0034097572
-
Enhancement of drug-induced apoptosis by antisense oligodeoxynucleotides targeted against Mdm2 and p21WAF1/CIP1
-
Sato N, Mizumoto K, Maehara N, Kusumoto M, Nishio S, Urashima T, Ogawa T and Tanaka M: Enhancement of drug-induced apoptosis by antisense oligodeoxynucleotides targeted against Mdm2 and p21WAF1/CIP1. Anticancer Res 20: 837-842, 2000.
-
(2000)
Anticancer Res
, vol.20
, pp. 837-842
-
-
Sato, N.1
Mizumoto, K.2
Maehara, N.3
Kusumoto, M.4
Nishio, S.5
Urashima, T.6
Ogawa, T.7
Tanaka, M.8
-
90
-
-
1942469420
-
A modified p53 enhances apoptosis in sarcoma cell lines mediated by doxorubicin
-
Tang HJ, Qian D, Sondak VK, Stachura S and Lin J: A modified p53 enhances apoptosis in sarcoma cell lines mediated by doxorubicin. Br J Cancer 90: 1285-1292, 2004.
-
(2004)
Br J Cancer
, vol.90
, pp. 1285-1292
-
-
Tang, H.J.1
Qian, D.2
Sondak, V.K.3
Stachura, S.4
Lin, J.5
-
91
-
-
0031839485
-
Association of loss of heterozygosity at the p53 locus with chemoresistance in osteosarcomas
-
Goto A, Kanda H, Ishikawa Y, et al: Association of loss of heterozygosity at the p53 locus with chemoresistance in osteosarcomas. Jpn J Cancer Res 89: 539-547, 1998.
-
(1998)
Jpn J Cancer Res
, vol.89
, pp. 539-547
-
-
Goto, A.1
Kanda, H.2
Ishikawa, Y.3
-
92
-
-
0006988841
-
P53 overexpression as an indicator of overall survival and response to treatment in osteosarcomas
-
Pápai Z, Féja CN, Hanna EN, Sztán M, Oláh E and Szendrôi M: P53 overexpression as an indicator of overall survival and response to treatment in osteosarcomas. Pathol Oncol Res 3: 15-19, 1997.
-
(1997)
Pathol Oncol Res
, vol.3
, pp. 15-19
-
-
Pápai, Z.1
Féja, C.N.2
Hanna, E.N.3
Sztán, M.4
Oláh, E.5
Szendrôi, M.6
-
93
-
-
67650137057
-
The effect of resistance-related proteins on the prognosis and survival of patients with osteosarcoma: An immunohistochemical analysis
-
In Turkish
-
Ozger H, Eralp L, Atalar AC, et al: The effect of resistance-related proteins on the prognosis and survival of patients with osteosarcoma: an immunohistochemical analysis. Acta Orthop Traumatol Turc 43: 28-34, 2009 (In Turkish).
-
(2009)
Acta Orthop Traumatol Turc
, vol.43
, pp. 28-34
-
-
Ozger, H.1
Eralp, L.2
Atalar, A.C.3
-
94
-
-
20144381477
-
TP53 mutations and outcome in osteosarcoma: A prospective, multicenter study
-
Wunder JS, Gokgoz N, Parkes R, et al: TP53 mutations and outcome in osteosarcoma: a prospective, multicenter study. J Clin Oncol 23: 1483-1490, 2005.
-
(2005)
J Clin Oncol
, vol.23
, pp. 1483-1490
-
-
Wunder, J.S.1
Gokgoz, N.2
Parkes, R.3
-
95
-
-
0031918223
-
BCL-2 family: Regulators of cell death
-
Chao DT and Korsmeyer SJ: BCL-2 family: regulators of cell death. Ann Rev Immunol 16: 395-419, 1998.
-
(1998)
Ann Rev Immunol
, vol.16
, pp. 395-419
-
-
Chao, D.T.1
Korsmeyer, S.J.2
-
96
-
-
0030979773
-
Double identity for proteins of the Bcl-2 family
-
Reed JC: Double identity for proteins of the Bcl-2 family. Nature 387: 773-776, 1997.
-
(1997)
Nature
, vol.387
, pp. 773-776
-
-
Reed, J.C.1
-
97
-
-
0033119372
-
BCL-2 gene family and the regulation of programmed cell death
-
Korsmeyer SJ: BCL-2 gene family and the regulation of programmed cell death. Cancer Res 59 (7 Suppl): 1693s-1700s, 1999.
-
(1999)
Cancer Res
, vol.59
, Issue.7 SUPPL.
-
-
Korsmeyer, S.J.1
-
98
-
-
27844455674
-
bcl-2/bax expression and p53 gene status in human bladder cancer: Relationship to early recurrence with intravesical chemotherapy after resection
-
Ye D, Li H, Qian S, Sun Y, Zheng J and Ma Y: bcl-2/bax expression and p53 gene status in human bladder cancer: relationship to early recurrence with intravesical chemotherapy after resection. J Urol 160: 2025-2029, 1998.
-
(1998)
J Urol
, vol.160
, pp. 2025-2029
-
-
Ye, D.1
Li, H.2
Qian, S.3
Sun, Y.4
Zheng, J.5
Ma, Y.6
-
99
-
-
0032610195
-
The relationship between cisplatin-induced apoptosis and p53, bcl-2 and bax expression in human lung cancer cells
-
Han JY, Chung YJ, Park SW, Kim JS, Rhyu MG, Kim HK and Lee KS: The relationship between cisplatin-induced apoptosis and p53, bcl-2 and bax expression in human lung cancer cells. Korean J Intern Med 14: 42-52, 1999.
-
(1999)
Korean J Intern Med
, vol.14
, pp. 42-52
-
-
Han, J.Y.1
Chung, Y.J.2
Park, S.W.3
Kim, J.S.4
Rhyu, M.G.5
Kim, H.K.6
Lee, K.S.7
-
100
-
-
0032743892
-
Chemosensitivity of human hepatocellular carcinoma cell line QGY-7703 is related to bcl-2 protein levels
-
Luo D, Cheng SC, Xie H and Xie Y: Chemosensitivity of human hepatocellular carcinoma cell line QGY-7703 is related to bcl-2 protein levels. Tumour Biol 20: 331-340, 1999.
-
(1999)
Tumour Biol
, vol.20
, pp. 331-340
-
-
Luo, D.1
Cheng, S.C.2
Xie, H.3
Xie, Y.4
-
101
-
-
4544263294
-
Molecular mechanism of chemoresistance to cisplatin in ovarian cancer cell lines
-
Murata T, Haisa M, Uetsuka H, et al: Molecular mechanism of chemoresistance to cisplatin in ovarian cancer cell lines. Int J Mol Med 13: 865-868, 2004.
-
(2004)
Int J Mol Med
, vol.13
, pp. 865-868
-
-
Murata, T.1
Haisa, M.2
Uetsuka, H.3
-
102
-
-
0002336719
-
Role of apoptosis and apoptosis-related proteins in the cisplatin-resistant phenotype of human tumor cell lines
-
Perego P, Righetti SC, Supino R, et al: Role of apoptosis and apoptosis-related proteins in the cisplatin-resistant phenotype of human tumor cell lines. Apoptosis 2: 540-548, 1997.
-
(1997)
Apoptosis
, vol.2
, pp. 540-548
-
-
Perego, P.1
Righetti, S.C.2
Supino, R.3
-
103
-
-
70449715116
-
Enhanced chemosensitivity of drug-resistant osteosarcoma cells by lentivirus-mediated Bcl-2 silencing
-
Zhao Y, Zhang CL, Zeng BF, Wu XS, Gao TT and Oda Y: Enhanced chemosensitivity of drug-resistant osteosarcoma cells by lentivirus-mediated Bcl-2 silencing. Biochem Biophys Res Commun 390: 642-647, 2009.
-
(2009)
Biochem Biophys Res Commun
, vol.390
, pp. 642-647
-
-
Zhao, Y.1
Zhang, C.L.2
Zeng, B.F.3
Wu, X.S.4
Gao, T.T.5
Oda, Y.6
-
104
-
-
84876270484
-
Enhanced chemosensitivity by simultaneously inhibiting cell cycle progression and promoting apoptosis of drug-resistant osteosarcoma MG63/DXR cells by targeting Cyclin D1 and Bcl-2
-
Zhang C, Zhao Y and Zeng B: Enhanced chemosensitivity by simultaneously inhibiting cell cycle progression and promoting apoptosis of drug-resistant osteosarcoma MG63/DXR cells by targeting Cyclin D1 and Bcl-2. Cancer Biomark 12: 155-167, 2012.
-
(2012)
Cancer Biomark
, vol.12
, pp. 155-167
-
-
Zhang, C.1
Zhao, Y.2
Zeng, B.3
-
105
-
-
0034629336
-
Lack of oxidative phosphorylation and low mitochondrial membrane potential decrease susceptibility to apoptosis and do not modulate the protective effect of Bcl-x(L) in osteosarcoma cells
-
Dey R and Moraes CT: Lack of oxidative phosphorylation and low mitochondrial membrane potential decrease susceptibility to apoptosis and do not modulate the protective effect of Bcl-x(L) in osteosarcoma cells. J Biol Chem 275: 7087-7094, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 7087-7094
-
-
Dey, R.1
Moraes, C.T.2
-
106
-
-
1342332363
-
Antisense to apoptosis inhibitors facilitates chemotherapy and TRAIL-induced death signaling
-
Zangemeister-Wittke U: Antisense to apoptosis inhibitors facilitates chemotherapy and TRAIL-induced death signaling. Ann NY Acad Sci 1002: 90-94, 2003.
-
(2003)
Ann NY Acad Sci
, vol.1002
, pp. 90-94
-
-
Zangemeister-Wittke, U.1
-
107
-
-
0034602188
-
Role of BAX in the apoptotic response to anticancer agents
-
Zhang L, Yu J, Park BH, et al: Role of BAX in the apoptotic response to anticancer agents. Science 290: 989-992, 2000.
-
(2000)
Science
, vol.290
, pp. 989-992
-
-
Zhang, L.1
Yu, J.2
Park, B.H.3
-
108
-
-
44849116896
-
Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apoptosis
-
Eliseev RA, Dong YF Sampson E, et al: Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apoptosis. Oncogene 27: 3605-3614, 2008.
-
(2008)
Oncogene
, vol.27
, pp. 3605-3614
-
-
Eliseev, R.A.1
Dong, Y.F.2
Sampson, E.3
-
109
-
-
47249134609
-
c-Myc and caspase-2 are involved in activating Bax during cytotoxic drug-induced apoptosis
-
Cao X, Bennett RL and May WS: c-Myc and caspase-2 are involved in activating Bax during cytotoxic drug-induced apoptosis. J Biol Chem 283: 14490-14496, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 14490-14496
-
-
Cao, X.1
Bennett, R.L.2
May, W.S.3
-
110
-
-
1942498999
-
Evaluation of P-glycoprotein, HER-2/ErbB-2, p53, and Bcl-2 in primary tumor and metachronous lung metastases in patients with high-grade osteosarcoma
-
Ferrari S, Bertoni F, Zanella L, et al: Evaluation of P-glycoprotein, HER-2/ErbB-2, p53, and Bcl-2 in primary tumor and metachronous lung metastases in patients with high-grade osteosarcoma. Cancer 100: 1936-1942, 2004.
-
(2004)
Cancer
, vol.100
, pp. 1936-1942
-
-
Ferrari, S.1
Bertoni, F.2
Zanella, L.3
-
111
-
-
84858797071
-
Expressions of p53, c-MYC, BCL-2 and apoptotic index in human osteosarcoma and their correlations with prognosis of patients
-
Wu X, Cai ZD, Lou LM and Zhu YB: Expressions of p53, c-MYC, BCL-2 and apoptotic index in human osteosarcoma and their correlations with prognosis of patients. Cancer Epidemiol 36: 212-216, 2012.
-
(2012)
Cancer Epidemiol
, vol.36
, pp. 212-216
-
-
Wu, X.1
Cai, Z.D.2
Lou, L.M.3
Zhu, Y.B.4
-
112
-
-
77955983894
-
Functional and biological analysis of Bcl-xL expression in human osteosarcoma
-
Wang ZX, Yang JS, Pan X, Wang JR, Li J, Yin YM and De W: Functional and biological analysis of Bcl-xL expression in human osteosarcoma. Bone 47: 445-454, 2010.
-
(2010)
Bone
, vol.47
, pp. 445-454
-
-
Wang, Z.X.1
Yang, J.S.2
Pan, X.3
Wang, J.R.4
Li, J.5
Yin, Y.M.6
De, W.7
-
113
-
-
36849017898
-
Livin and Bcl-2 expression in high-grade osteosarcoma
-
Nedelcu T, Kubista B, Koller A, et al: Livin and Bcl-2 expression in high-grade osteosarcoma. J Cancer Res Clin Oncol 134: 237-244, 2008.
-
(2008)
J Cancer Res Clin Oncol
, vol.134
, pp. 237-244
-
-
Nedelcu, T.1
Kubista, B.2
Koller, A.3
-
114
-
-
39749134998
-
Prognostic value of bax, bcl-2, and p53 staining in primary osteosarcoma
-
Kaseta MK, Khaldi L, Gomatos IP, et al: Prognostic value of bax, bcl-2, and p53 staining in primary osteosarcoma. J Surg Oncol 97: 259-266, 2008.
-
(2008)
J Surg Oncol
, vol.97
, pp. 259-266
-
-
Kaseta, M.K.1
Khaldi, L.2
Gomatos, I.P.3
-
115
-
-
37549031248
-
Prognostic value of bax, cytochrome C, and caspase-8 protein expression in primary osteosarcoma
-
Kaseta MK, Gomatos IP, Khaldi L, et al: Prognostic value of bax, cytochrome C, and caspase-8 protein expression in primary osteosarcoma. Hybridoma (Larchmt) 26: 355-362, 2007.
-
(2007)
Hybridoma (Larchmt)
, vol.26
, pp. 355-362
-
-
Kaseta, M.K.1
Gomatos, I.P.2
Khaldi, L.3
-
116
-
-
33745713171
-
Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis
-
Degenhardt K, Mathew R, Beaudoin B, et al: Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis. Cancer Cell 10: 51-64, 2006.
-
(2006)
Cancer Cell
, vol.10
, pp. 51-64
-
-
Degenhardt, K.1
Mathew, R.2
Beaudoin, B.3
-
117
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
Klionsky DJ and Emr SD: Autophagy as a regulated pathway of cellular degradation. Science 290: 1717-1721, 2000.
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
119
-
-
56749170677
-
Autophagic cell death: The story of a misnomer
-
Kroemer G and Levine B: Autophagic cell death: the story of a misnomer. Nat Rev Mol Cell Biol 9: 1004-1010, 2008.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 1004-1010
-
-
Kroemer, G.1
Levine, B.2
-
120
-
-
50349098812
-
Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells
-
Han J, Hou W, Goldstein LA, et al: Involvement of protective autophagy in TRAIL resistance of apoptosis-defective tumor cells. J Biol Chem 283: 19665-19677, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 19665-19677
-
-
Han, J.1
Hou, W.2
Goldstein, L.A.3
-
121
-
-
33846794896
-
Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma
-
Amaravadi RK, Yu D, Lum JJ, et al: Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma. J Clin Invest 117: 326-336, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 326-336
-
-
Amaravadi, R.K.1
Yu, D.2
Lum, J.J.3
-
122
-
-
77958575758
-
Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation
-
Carew JS, Medina EC, Esquivel JA II, et al: Autophagy inhibition enhances vorinostat-induced apoptosis via ubiquitinated protein accumulation. J Cell Mol Med 14: 2448-2459, 2010.
-
(2010)
J Cell Mol Med
, vol.14
, pp. 2448-2459
-
-
Carew, J.S.1
Medina, E.C.2
Esquivel, J.A.I.I.3
-
123
-
-
77953383616
-
Autophagy blockade sensitizes prostate cancer cells towards Src family kinase inhibitors
-
Wu Z, Chang PC, Yang JC, et al: Autophagy blockade sensitizes prostate cancer cells towards Src family kinase inhibitors. Genes Cancer 1: 40-49, 2010.
-
(2010)
Genes Cancer
, vol.1
, pp. 40-49
-
-
Wu, Z.1
Chang, P.C.2
Yang, J.C.3
-
124
-
-
77953289524
-
Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model
-
Li J, Hou N, Faried A, Tsutsumi S and Kuwano H: Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model. Eur J Cancer 46: 1900-1909, 2010.
-
(2010)
Eur J Cancer
, vol.46
, pp. 1900-1909
-
-
Li, J.1
Hou, N.2
Faried, A.3
Tsutsumi, S.4
Kuwano, H.5
-
125
-
-
69949106925
-
The double-edged sword of autophagy modulation in cancer
-
White E and DiPaola RS: The double-edged sword of autophagy modulation in cancer. Clin Cancer Res 15: 5308-5316, 2009.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 5308-5316
-
-
White, E.1
Dipaola, R.S.2
-
126
-
-
33847008972
-
DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells
-
Katayama M, Kawaguchi T, Berger MS and Pieper RO: DNA damaging agent-induced autophagy produces a cytoprotective adenosine triphosphate surge in malignant glioma cells. Cell Death Differ 14: 548-558, 2007.
-
(2007)
Cell Death Differ
, vol.14
, pp. 548-558
-
-
Katayama, M.1
Kawaguchi, T.2
Berger, M.S.3
Pieper, R.O.4
-
127
-
-
34347394714
-
Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance
-
Carew JS, Nawrocki ST, Kahue CN, et al: Targeting autophagy augments the anticancer activity of the histone deacetylase inhibitor SAHA to overcome Bcr-Abl-mediated drug resistance. Blood 110: 313-322, 2007.
-
(2007)
Blood
, vol.110
, pp. 313-322
-
-
Carew, J.S.1
Nawrocki, S.T.2
Kahue, C.N.3
-
128
-
-
54249104991
-
Autophagy: A novel mechanism of synergistic cytotoxicity between doxorubicin and roscovitine in a sarcoma model
-
Lambert LA, Qiao N, Hunt KK, Lambert DH, Mills GB, Meijer L and Keyomarsi K: Autophagy: a novel mechanism of synergistic cytotoxicity between doxorubicin and roscovitine in a sarcoma model. Cancer Res 68: 7966-7974, 2008.
-
(2008)
Cancer Res
, vol.68
, pp. 7966-7974
-
-
Lambert, L.A.1
Qiao, N.2
Hunt, K.K.3
Lambert, D.H.4
Mills, G.B.5
Meijer, L.6
Keyomarsi, K.7
-
129
-
-
58149104056
-
The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells
-
Meschini S, Condello M, Calcabrini A, et al: The plant alkaloid voacamine induces apoptosis-independent autophagic cell death on both sensitive and multidrug resistant human osteosarcoma cells. Autophagy 4: 1020-1033, 2008.
-
(2008)
Autophagy
, vol.4
, pp. 1020-1033
-
-
Meschini, S.1
Condello, M.2
Calcabrini, A.3
-
130
-
-
84876576952
-
Cytoprotective role of autophagy during paclitaxel-induced apoptosis in Saos-2 osteosarcoma cells
-
Kim HJ, Lee SG, Kim YJ, Park JE, Lee KY, Yoo YH and Kim JM: Cytoprotective role of autophagy during paclitaxel-induced apoptosis in Saos-2 osteosarcoma cells. Int J Oncol 42: 1985-1992, 2013.
-
(2013)
Int J Oncol
, vol.42
, pp. 1985-1992
-
-
Kim, H.J.1
Lee, S.G.2
Kim, Y.J.3
Park, J.E.4
Lee, K.Y.5
Yoo, Y.H.6
Kim, J.M.7
-
131
-
-
77149172547
-
Expression of Beclin1 in osteosarcoma and the effects of down-regulation of autophagy on the chemotherapeutic sensitivity
-
Zhang Z, Shao Z, Xiong L, Che B, Deng C and Xu W: Expression of Beclin1 in osteosarcoma and the effects of down-regulation of autophagy on the chemotherapeutic sensitivity. J Huazhong Univ Sci Technolog Med Sci 29: 737-740, 2009.
-
(2009)
J Huazhong Univ Sci Technolog Med Sci
, vol.29
, pp. 737-740
-
-
Zhang, Z.1
Shao, Z.2
Xiong, L.3
Che, B.4
Deng, C.5
Xu, W.6
-
132
-
-
80052060417
-
RIP3 expression induces a death profile change in U2OS osteosarcoma cells after 5-ALA-PDT
-
Coupienne I, Fettweis G and Piette J: RIP3 expression induces a death profile change in U2OS osteosarcoma cells after 5-ALA-PDT. Lasers Surg Med 43: 557-564, 2011.
-
(2011)
Lasers Surg Med
, vol.43
, pp. 557-564
-
-
Coupienne, I.1
Fettweis, G.2
Piette, J.3
-
133
-
-
84855406005
-
HMGB1 promotes drug resistance in osteosarcoma
-
Huang J, Ni J, Liu K, et al: HMGB1 promotes drug resistance in osteosarcoma. Cancer Res 72: 230-238, 2012.
-
(2012)
Cancer Res
, vol.72
, pp. 230-238
-
-
Huang, J.1
Ni, J.2
Liu, K.3
-
134
-
-
85046981421
-
Targeting HMGB1-mediated autophagy as a novel therapeutic strategy for osteosarcoma
-
Huang J, Liu K, Yu Y, et al: Targeting HMGB1-mediated autophagy as a novel therapeutic strategy for osteosarcoma. Autophagy 8: 275-277, 2012.
-
(2012)
Autophagy
, vol.8
, pp. 275-277
-
-
Huang, J.1
Liu, K.2
Yu, Y.3
-
136
-
-
20444460289
-
MicroRNA expression profiles classify human cancers
-
Lu J, Getz G, Miska EA, et al: MicroRNA expression profiles classify human cancers. Nature 435: 834-838, 2005.
-
(2005)
Nature
, vol.435
, pp. 834-838
-
-
Lu, J.1
Getz, G.2
Miska, E.A.3
-
137
-
-
33144490646
-
A microRNA expression signature of human solid tumors defines cancer gene targets
-
Volinia S, Calin GA, Liu CG, et al: A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 103: 2257-2261, 2006.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 2257-2261
-
-
Volinia, S.1
Calin, G.A.2
Liu, C.G.3
-
138
-
-
84856732824
-
miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy
-
Nakatani F, Ferracin M, Manara MC, et al: miR-34a predicts survival of Ewing's sarcoma patients and directly influences cell chemo-sensitivity and malignancy. J Pathol 226: 796-805, 2012.
-
(2012)
J Pathol
, vol.226
, pp. 796-805
-
-
Nakatani, F.1
Ferracin, M.2
Manara, M.C.3
-
139
-
-
79958048319
-
Micro-RNA profiles in osteosarcoma as a predictive tool for ifosfamide response
-
Gougelet A, Pissaloux D, Besse A, et al: Micro-RNA profiles in osteosarcoma as a predictive tool for ifosfamide response. Int J Cancer 129: 680-690, 2011.
-
(2011)
Int J Cancer
, vol.129
, pp. 680-690
-
-
Gougelet, A.1
Pissaloux, D.2
Besse, A.3
-
140
-
-
70450237022
-
Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells
-
Song B, Wang Y, Xi Y, et al: Mechanism of chemoresistance mediated by miR-140 in human osteosarcoma and colon cancer cells. Oncogene 28: 4065-4074, 2009.
-
(2009)
Oncogene
, vol.28
, pp. 4065-4074
-
-
Song, B.1
Wang, Y.2
Xi, Y.3
-
141
-
-
77951597361
-
Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells
-
Song B, Wang Y, Titmus MA, Botchkina G, Formentini A, Kornmann M and Ju J: Molecular mechanism of chemoresistance by miR-215 in osteosarcoma and colon cancer cells. Mol Cancer 9: 96, 2010.
-
(2010)
Mol Cancer
, vol.9
, pp. 96
-
-
Song, B.1
Wang, Y.2
Titmus, M.A.3
Botchkina, G.4
Formentini, A.5
Kornmann, M.6
Ju, J.7
-
142
-
-
84866436241
-
miR-15a and miR-16-1 downregulate CCND1 and induce apoptosis and cell cycle arrest in osteosarcoma
-
Cai CK, Zhao GY, Tian LY, et al: miR-15a and miR-16-1 downregulate CCND1 and induce apoptosis and cell cycle arrest in osteosarcoma. Oncol Rep 28: 1764-1770, 2012.
-
(2012)
Oncol Rep
, vol.28
, pp. 1764-1770
-
-
Cai, C.K.1
Zhao, G.Y.2
Tian, L.Y.3
-
143
-
-
78651140052
-
The role of tumor stem-cells in regrowth of the tumor following drastic applications
-
Makino S: The role of tumor stem-cells in regrowth of the tumor following drastic applications. Acta Unio Int Contra Cancrum 15 (Suppl 1): 196-198, 1959.
-
(1959)
Acta Unio Int Contra Cancrum
, vol.15
, Issue.SUPPL. 1
, pp. 196-198
-
-
Makino, S.1
-
144
-
-
0030789242
-
Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell
-
Bonnet D and Dick JE: Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell. Nat Med 3: 730-737, 1997.
-
(1997)
Nat Med
, vol.3
, pp. 730-737
-
-
Bonnet, D.1
Dick, J.E.2
-
145
-
-
0036737914
-
Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
-
Ignatova TN, Kukekov VG, Laywell ED, Suslov ON, Vrionis FD and Steindler DA: Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro. Glia 39: 193-206, 2002.
-
(2002)
Glia
, vol.39
, pp. 193-206
-
-
Ignatova, T.N.1
Kukekov, V.G.2
Laywell, E.D.3
Suslov, O.N.4
Vrionis, F.D.5
Steindler, D.A.6
-
146
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh SK, Clarke ID, Terasaki M, et al: Identification of a cancer stem cell in human brain tumors. Cancer Res 63: 5821-5828, 2003.
-
(2003)
Cancer Res
, vol.63
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
-
147
-
-
80155187103
-
Cancer stem cells in osteosarcoma: Recent progress and perspective
-
Liu B, Ma W, Jha RK and Gurung K: Cancer stem cells in osteosarcoma: recent progress and perspective. Acta Oncol 50: 1142-1150, 2011.
-
(2011)
Acta Oncol
, vol.50
, pp. 1142-1150
-
-
Liu, B.1
Ma, W.2
Jha, R.K.3
Gurung, K.4
-
148
-
-
47949086256
-
Cancer stem cells: Markers or biomarkers?
-
Woodward WA and Sulman EP: Cancer stem cells: markers or biomarkers? Cancer Metastasis Rev 27: 459-470, 2008.
-
(2008)
Cancer Metastasis Rev
, vol.27
, pp. 459-470
-
-
Woodward, W.A.1
Sulman, E.P.2
-
149
-
-
76749122743
-
Resistance of stem-like cells from neuroblastoma cell lines to commonly used chemotherapeutic agents
-
Vangipuram SD, Wang ZJ and Lyman WD: Resistance of stem-like cells from neuroblastoma cell lines to commonly used chemotherapeutic agents. Pediatr Blood Cancer 54: 361-368, 2010.
-
(2010)
Pediatr Blood Cancer
, vol.54
, pp. 361-368
-
-
Vangipuram, S.D.1
Wang, Z.J.2
Lyman, W.D.3
-
150
-
-
62149151311
-
Identification and expansion of human osteosarcoma-cancer-stem cells by long-term 3-aminobenzamide treatment
-
Di Fiore R, Santulli A, Ferrante RD, et al: Identification and expansion of human osteosarcoma-cancer-stem cells by long-term 3-aminobenzamide treatment. J Cell Physiol 219: 301-313, 2009.
-
(2009)
J Cell Physiol
, vol.219
, pp. 301-313
-
-
Di Fiore, R.1
Santulli, A.2
Ferrante, R.D.3
-
151
-
-
67649424217
-
Sphere-forming stem-like cell populations with drug resistance in human sarcoma cell lines
-
Fujii H, Honoki K, Tsujiuchi T, Kido A, Yoshitani K and Takakura Y: Sphere-forming stem-like cell populations with drug resistance in human sarcoma cell lines. Int J Oncol 34: 1381-1386, 2009.
-
(2009)
Int J Oncol
, vol.34
, pp. 1381-1386
-
-
Fujii, H.1
Honoki, K.2
Tsujiuchi, T.3
Kido, A.4
Yoshitani, K.5
Takakura, Y.6
-
152
-
-
77954351665
-
Possible involvement of stem-like populations with elevated ALDH1 in sarcomas for chemotherapeutic drug resistance
-
Honoki K, Fujii H, Kubo A, Kido A, Mori T, Tanaka Y and Tsujiuchi T: Possible involvement of stem-like populations with elevated ALDH1 in sarcomas for chemotherapeutic drug resistance. Oncol Rep 24: 501-505, 2010.
-
(2010)
Oncol Rep
, vol.24
, pp. 501-505
-
-
Honoki, K.1
Fujii, H.2
Kubo, A.3
Kido, A.4
Mori, T.5
Tanaka, Y.6
Tsujiuchi, T.7
-
153
-
-
84859187031
-
Therapeutic implications of an enriched cancer stem-like cell population in a human osteosarcoma cell line
-
Martins-Neves SR, Lopes ÁO, do Carmo A, et al: Therapeutic implications of an enriched cancer stem-like cell population in a human osteosarcoma cell line. BMC Cancer 12: 139, 2012.
-
(2012)
BMC Cancer
, vol.12
, pp. 139
-
-
Martins-Neves, S.R.1
Lopes, A.O.2
do Carmo, A.3
-
154
-
-
27644497180
-
Treatment of osteosarcoma at first recurrence after contemporary therapy: The Memorial Sloan-Kettering Cancer Center experience
-
Chou AJ, Merola PR, Wexler LH, et al: Treatment of osteosarcoma at first recurrence after contemporary therapy: the Memorial Sloan-Kettering Cancer Center experience. Cancer 104: 2214-2221, 2005.
-
(2005)
Cancer
, vol.104
, pp. 2214-2221
-
-
Chou, A.J.1
Merola, P.R.2
Wexler, L.H.3
-
155
-
-
19944411434
-
Efficacy and safety of liposomal anthracyclines in phase I/II clinical trials
-
Alberts DS, Muggia FM, Carmichael J, et al: Efficacy and safety of liposomal anthracyclines in phase I/II clinical trials. Semin Oncol 31 (Suppl 13): S53-S90, 2004.
-
(2004)
Semin Oncol
, vol.31
, Issue.SUPPL. 13
-
-
Alberts, D.S.1
Muggia, F.M.2
Carmichael, J.3
-
156
-
-
84879780600
-
Autophagy: Shaping the tumor microenvironment and therapeutic response
-
Maes H, Rubio N, Garg AD and Agostinis P: Autophagy: shaping the tumor microenvironment and therapeutic response. Trends Mol Med 19: 428-446, 2013.
-
(2013)
Trends Mol Med
, vol.19
, pp. 428-446
-
-
Maes, H.1
Rubio, N.2
Garg, A.D.3
Agostinis, P.4
|