Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apoptosis

Oncogene

Volumn 27, Issue 25, 2008, Pages 3605-3614

  Eliseev, R A ^a   Dong, Y F ^a   Sampson, E ^a   Zuscik, M J ^a   Schwarz, E M ^a   O'Keefe, R J ^a   Rosier, R N ^a   Drissi, M H ^b  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Apoptosis; Bax; Osteosarcoma; Runx2

Indexed keywords

BONE MORPHOGENETIC PROTEIN; PROTEIN BAX; PROTEIN BCL 2; TRANSCRIPTION FACTOR RUNX2;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CONTROLLED STUDY; DATA ANALYSIS; GENE ACTIVATION; HUMAN; HUMAN CELL; MULTIGENE FAMILY; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN FUNCTION; REGULATORY SEQUENCE; SENSITIVITY ANALYSIS; UPREGULATION;

APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BONE NEOPLASMS; CASPASE 3; CELL LINE, TUMOR; CORE BINDING FACTOR ALPHA 1 SUBUNIT; GENE EXPRESSION REGULATION; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MODELS, BIOLOGICAL; MUTAGENESIS, SITE-DIRECTED; OSTEOSARCOMA; PROMOTER REGIONS (GENETICS); TRANS-ACTIVATION (GENETICS);

EID: 44849116896     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1211020     Document Type: Article

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