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Volumn 20, Issue 2 A, 2000, Pages 837-842

Enhancement of drug-induced apoptosis by antisense oligodeoxynucleotides targeted against Mdm2 and p21(WAF1/CIP1)

Author keywords

Antisense oligodeoxynucleotide; Apoptosis; Cisplatin; Mdm2; Mitomycin C; P21(WAF1 CIP1)

Indexed keywords

ANTINEOPLASTIC ANTIBIOTIC; ANTINEOPLASTIC METAL COMPLEX; ANTISENSE OLIGODEOXYNUCLEOTIDE; CISPLATIN; MESSENGER RNA; MITOMYCIN C; PROTEIN MDM2; PROTEIN P21; PROTEIN P53;

EID: 0034097572     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (34)

References (41)
  • 1
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe SW, Ruley HE, Jacks T and Housman DE: p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74: 957-967, 1993.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 2
    • 0030941458 scopus 로고    scopus 로고
    • p53 the cellular gatekeener for growth and division
    • Levine AJ: p53 the cellular gatekeener for growth and division. Cell 88: 323-331, 1997.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 3
    • 0029845760 scopus 로고    scopus 로고
    • Structure and function of the p53 tumor suppressor gene: Clues for rational cancer therapeutic strategies
    • Harris CC: Structure and function of the p53 tumor suppressor gene: clues for rational cancer therapeutic strategies. J Natl Cancer Inst 88: 1442-1455, 1996.
    • (1996) J Natl Cancer Inst , vol.88 , pp. 1442-1455
    • Harris, C.C.1
  • 5
    • 0025853776 scopus 로고
    • Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line
    • Fakharzadeh SS, Trusko SP and George DL: Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line. EMBO J 10: 1565-1569, 1991.
    • (1991) EMBO J , vol.10 , pp. 1565-1569
    • Fakharzadeh, S.S.1    Trusko, S.P.2    George, D.L.3
  • 6
    • 0026649648 scopus 로고
    • The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation
    • Momand J, Zambetti GP, Olson DC, George D and Levine AJ: The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation. Cell 69: 1237-1245, 1992.
    • (1992) Cell , vol.69 , pp. 1237-1245
    • Momand, J.1    Zambetti, G.P.2    Olson, D.C.3    George, D.4    Levine, A.J.5
  • 8
    • 0030905284 scopus 로고    scopus 로고
    • Mdm2 promotes the rapid degradation of p53
    • Haupt Y, Maya R, Kazaz A and Oren M: Mdm2 promotes the rapid degradation of p53. Nature 387: 296-299, 1997.
    • (1997) Nature , vol.387 , pp. 296-299
    • Haupt, Y.1    Maya, R.2    Kazaz, A.3    Oren, M.4
  • 10
    • 0027244853 scopus 로고
    • The p53-Mdm-2 autoregulatory feedback loop
    • Wu X, Bayle JH, Olson D and Levine AJ: The p53-Mdm-2 autoregulatory feedback loop. Genes Dev 7: 1126-1132, 1993.
    • (1993) Genes Dev , vol.7 , pp. 1126-1132
    • Wu, X.1    Bayle, J.H.2    Olson, D.3    Levine, A.J.4
  • 11
    • 0030795068 scopus 로고    scopus 로고
    • Translational enhancement of Mdm2 oncogene expression in human tumor cells containing a stabilized wild-type p53 protein
    • Landers JE, Cassel SL and George DL: Translational enhancement of Mdm2 oncogene expression in human tumor cells containing a stabilized wild-type p53 protein. Cancer Res 57: 3562-3568, 1997.
    • (1997) Cancer Res , vol.57 , pp. 3562-3568
    • Landers, J.E.1    Cassel, S.L.2    George, D.L.3
  • 14
  • 16
    • 0027496935 scopus 로고
    • The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases
    • Harper JW, Adami GR, Wei N, Keyomarsi K and Elledge SJ: The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75: 805-816, 1993.
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wei, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 20
    • 0033528830 scopus 로고    scopus 로고
    • waf1/cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53
    • waf1/cip1/Sdi1 induces permanent growth arrest with markers of replicative senescence in human tumor cells lacking functional p53. Oncogene 18: 2789-2797, 1999.
    • (1999) Oncogene , vol.18 , pp. 2789-2797
    • Fang, L.1    Igarashi, M.2    Leung, J.3    Sugrue, M.M.4    Lee, S.W.5    Aaronson, S.A.6
  • 21
    • 0029811984 scopus 로고    scopus 로고
    • Genetic determinants of p53-induced apoptosis and growth arrest
    • Polyak K, Waldman T, He TC, Kinzler KW and Vogelstein B: Genetic determinants of p53-induced apoptosis and growth arrest. Genes Dev 10: 1945-1952, 1996.
    • (1996) Genes Dev , vol.10 , pp. 1945-1952
    • Polyak, K.1    Waldman, T.2    He, T.C.3    Kinzler, K.W.4    Vogelstein, B.5
  • 24
    • 0032474904 scopus 로고    scopus 로고
    • p21-induced cycle arrest in G1 protects cells from apoptosis induced by UV-irradiation or RNA polymerase II blockage
    • Bissonnette N and Hunting DJ: p21-induced cycle arrest in G1 protects cells from apoptosis induced by UV-irradiation or RNA polymerase II blockage. Oncogene 16: 3461-3469, 1998.
    • (1998) Oncogene , vol.16 , pp. 3461-3469
    • Bissonnette, N.1    Hunting, D.J.2
  • 25
    • 0033594245 scopus 로고    scopus 로고
    • Induced p21waf1 expression in HI299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin
    • Wang Y, Blandino G and Givol D: Induced p21waf1 expression in HI299 cell line promotes cell senescence and protects against cytotoxic effect of radiation and doxorubicin. Oncogene 18: 2643-2649, 1999.
    • (1999) Oncogene , vol.18 , pp. 2643-2649
    • Wang, Y.1    Blandino, G.2    Givol, D.3
  • 26
    • 0031939875 scopus 로고    scopus 로고
    • Synergistic activation of p53 by inhibition of Mdm2 expression and DNA damage
    • Chen L, Agrawal S, Zhou W, Zhang R and Chen J: Synergistic activation of p53 by inhibition of Mdm2 expression and DNA damage. Proc Natl Acad Sci USA 95: 195-200, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 195-200
    • Chen, L.1    Agrawal, S.2    Zhou, W.3    Zhang, R.4    Chen, J.5
  • 29
    • 0032974472 scopus 로고    scopus 로고
    • Quantitative determination of apoptotic death in cultured human pancreatic cancer cells by propidium iodide and digitonin
    • Zhang L, Mizumoto K, Sato N, Ogawa T, Kusumoto M, Niiyama H and Tanaka M: Quantitative determination of apoptotic death in cultured human pancreatic cancer cells by propidium iodide and digitonin. Cancer Lett 142: 129-137, 1999.
    • (1999) Cancer Lett , vol.142 , pp. 129-137
    • Zhang, L.1    Mizumoto, K.2    Sato, N.3    Ogawa, T.4    Kusumoto, M.5    Niiyama, H.6    Tanaka, M.7
  • 30
    • 0028273473 scopus 로고
    • Antisense oligonucleotide strategies in physiology
    • Baertschi AJ: Antisense oligonucleotide strategies in physiology. Mol Cell Endocrinol 101: 15-24, 1994.
    • (1994) Mol Cell Endocrinol , vol.101 , pp. 15-24
    • Baertschi, A.J.1
  • 31
    • 0032439330 scopus 로고    scopus 로고
    • Cellular delivery is a major obstacle for oligodeoxynucleotide inhibition of telomerase activity
    • Duncan VE, Ajmani PS and Hughes JA: Cellular delivery is a major obstacle for oligodeoxynucleotide inhibition of telomerase activity. Anticancer Res 18: 4105-4108, 1998.
    • (1998) Anticancer Res , vol.18 , pp. 4105-4108
    • Duncan, V.E.1    Ajmani, P.S.2    Hughes, J.A.3
  • 32
    • 0030868484 scopus 로고    scopus 로고
    • Potent and selective gene inhibition using antisense oligodeoxynucleotides
    • Flanagan WM and Wagner RW: Potent and selective gene inhibition using antisense oligodeoxynucleotides. Mol Cell Biochem 172: 213-225, 1997.
    • (1997) Mol Cell Biochem , vol.172 , pp. 213-225
    • Flanagan, W.M.1    Wagner, R.W.2
  • 33
    • 0028577244 scopus 로고
    • Cationic liposomes improve stability and intracellular delivery of antisense oligonucleotides into CaSki cells
    • Lappalainen K, Urtti A, Soderling E, Jaaskelainen I, Syrjanen K and Syrjanen S: Cationic liposomes improve stability and intracellular delivery of antisense oligonucleotides into CaSki cells. Biochim Biophys Acta 1196: 201-208, 1994.
    • (1994) Biochim Biophys Acta , vol.1196 , pp. 201-208
    • Lappalainen, K.1    Urtti, A.2    Soderling, E.3    Jaaskelainen, I.4    Syrjanen, K.5    Syrjanen, S.6
  • 34
    • 0025864203 scopus 로고
    • Anti-sense phosphorothioate oligonucleotides have both specific and non-specific effects on cells containing human papillomavirus type 16
    • Storey A, Oates D, Banks L, Crawford L and Crook T: Anti-sense phosphorothioate oligonucleotides have both specific and non-specific effects on cells containing human papillomavirus type 16. Nucleic Acids Res 19: 4109-4114, 1991.
    • (1991) Nucleic Acids Res , vol.19 , pp. 4109-4114
    • Storey, A.1    Oates, D.2    Banks, L.3    Crawford, L.4    Crook, T.5
  • 35
    • 0028340194 scopus 로고
    • Sequence-independent induction of Sp1 transcription factor activity by phosphorothioate oligodeoxynucleotides
    • Perez JR, Li Y, Stein CA, Majumder S, Oorschot AV and Narayanan R: Sequence-independent induction of Sp1 transcription factor activity by phosphorothioate oligodeoxynucleotides. Proc Natl Acad Sci USA 91: 5957-5961, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 5957-5961
    • Perez, J.R.1    Li, Y.2    Stein, C.A.3    Majumder, S.4    Oorschot, A.V.5    Narayanan, R.6
  • 36
    • 0028953137 scopus 로고
    • Antisense oligonucleotides directed against p53 have antiproliferative effects unrelated to effects on p53 expression
    • Barton CM and Lemoine NR: Antisense oligonucleotides directed against p53 have antiproliferative effects unrelated to effects on p53 expression. Br J Cancer 71: 429-437, 1995.
    • (1995) Br J Cancer , vol.71 , pp. 429-437
    • Barton, C.M.1    Lemoine, N.R.2
  • 37
    • 0029913730 scopus 로고    scopus 로고
    • Mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein
    • Chen J, Wu X, Lin J and Levine AJ: Mdm-2 inhibits the G1 arrest and apoptosis functions of the p53 tumor suppressor protein. Mol Cell Biol 16: 2445-2453, 1996.
    • (1996) Mol Cell Biol , vol.16 , pp. 2445-2453
    • Chen, J.1    Wu, X.2    Lin, J.3    Levine, A.J.4
  • 38
    • 0029985647 scopus 로고    scopus 로고
    • Cell type-specific inhibition of p53-mediated apoptosis by Mdm2
    • Haupt Y, Barak Y and Oren M: Cell type-specific inhibition of p53-mediated apoptosis by Mdm2. EMBO J 15: 1596-1606, 1996.
    • (1996) EMBO J , vol.15 , pp. 1596-1606
    • Haupt, Y.1    Barak, Y.2    Oren, M.3
  • 40
    • 0029044606 scopus 로고
    • Mdm2 protein confers the resistance of a human glioblastoma cell line to cisplatin-induced apoptosis
    • Kondo S, Barnett GH, Hara H, Morimura T and Takeuchi J: Mdm2 protein confers the resistance of a human glioblastoma cell line to cisplatin-induced apoptosis. Oncogene 10: 2001-2006, 1995.
    • (1995) Oncogene , vol.10 , pp. 2001-2006
    • Kondo, S.1    Barnett, G.H.2    Hara, H.3    Morimura, T.4    Takeuchi, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.