Targeting Glutathione-S transferase enzymes in musculoskeletal sarcomas: A promising therapeutic strategy

Analytical Cellular Pathology

Volumn 34, Issue 3, 2011, Pages 131-145

  Pasello, Michela ^a   Manara, Maria Cristina ^a   Michelacci, Francesca ^a   Fanelli, Marilù ^a   Hattinger, Claudia Maria ^a   Nicoletti, Giordano ^a   Landuzzi, Lorena ^a   Lollini, Pier Luigi ^b   Caccuri, Annamaria ^c   Picci, Piero ^a   Scotlandi, Katia ^a   Serra, Massimo ^a  

^a RIZZOLI ORTHOPAEDIC INSTITUTE   (Italy)

^b UNIVERSITY OF BOLOGNA   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

glutathione metabolism; Musculoskeletal sarcomas; novel antitumour agents; target therapies

Indexed keywords

6 (7 NITRO 2,1,3 BENZOXADIAZOL 4 YLTHIOL)HEXANOL; ANTINEOPLASTIC AGENT; CISPLATIN; DOXORUBICIN; GLUTATHIONE TRANSFERASE; GLUTATHIONE TRANSFERASE A1; GLUTATHIONE TRANSFERASE M1; GLUTATHIONE TRANSFERASE P1; METHOTREXATE; UNCLASSIFIED DRUG; VINCRISTINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CHEMOTHERAPY; CONTROLLED STUDY; CYTOSTASIS; DRUG ANTAGONISM; DRUG POTENTIATION; EWING SARCOMA; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; METASTASIS; MOUSE; MUSCULOSKELETAL SYSTEM; NONHUMAN; OSTEOSARCOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TARGETING; RHABDOMYOSARCOMA;

ANIMALS; ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; BONE NEOPLASMS; CELL CYCLE; CELL LINE, TUMOR; CISPLATIN; DOSE-RESPONSE RELATIONSHIP, DRUG; DOXORUBICIN; DRUG INTERACTIONS; DRUG RESISTANCE, NEOPLASM; ENZYME INHIBITORS; GLUTATHIONE TRANSFERASE; HUMANS; ISOENZYMES; METHOTREXATE; MICE; MICE, NUDE; MUSCLE NEOPLASMS; MUSCLE, SKELETAL; OXADIAZOLES; SARCOMA; TIME FACTORS; TUMOR BURDEN; VINCRISTINE; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 79960809400     PISSN: 22107177     EISSN: 22107185     Source Type: Journal    
DOI: 10.3233/ACP-2011-012     Document Type: Article

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