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Volumn 42, Issue , 2014, Pages 116-131

A critical role for prefrontocortical endocannabinoid signaling in the regulation of stress and emotional behavior

Author keywords

Emotional behavior; Endocannabinoid system; Prefrontal cortex; Stress

Indexed keywords

CANNABINOID 1 RECEPTOR; ENDOCANNABINOID; MONOAMINE;

EID: 84896039080     PISSN: 01497634     EISSN: 18737528     Source Type: Journal    
DOI: 10.1016/j.neubiorev.2014.02.006     Document Type: Review
Times cited : (110)

References (236)
  • 1
    • 67649998667 scopus 로고    scopus 로고
    • Anxiolytic-like effects induced by blockade of transient receptor potential vanilloid type 1 (TRPV1) channels in the medial prefrontal cortex of rats
    • Aguiar D.C., Terzian A.L., Guimarães F.S., Moreira F.A. Anxiolytic-like effects induced by blockade of transient receptor potential vanilloid type 1 (TRPV1) channels in the medial prefrontal cortex of rats. Psychopharmacology (Berl.) 2009, 205:217-225.
    • (2009) Psychopharmacology (Berl.) , vol.205 , pp. 217-225
    • Aguiar, D.C.1    Terzian, A.L.2    Guimarães, F.S.3    Moreira, F.A.4
  • 2
    • 44849141696 scopus 로고    scopus 로고
    • Enzymatic pathways that regulate endocannabinoid signaling in the nervous system
    • Ahn K., McKinney M.K., Cravatt B.F. Enzymatic pathways that regulate endocannabinoid signaling in the nervous system. Chem. Rev. 2008, 108:1687-1707.
    • (2008) Chem. Rev. , vol.108 , pp. 1687-1707
    • Ahn, K.1    McKinney, M.K.2    Cravatt, B.F.3
  • 3
    • 41749106682 scopus 로고    scopus 로고
    • BDNF impairment in the hippocampus is related to enhanced despair behavior in CB1 knockout mice
    • Aso E., Ozaita A., Valdizan E.M., Ledent C., Pazos A., Maldonado R., Valverde O. BDNF impairment in the hippocampus is related to enhanced despair behavior in CB1 knockout mice. J. Neurochem. 2008, 105:565-572.
    • (2008) J. Neurochem. , vol.105 , pp. 565-572
    • Aso, E.1    Ozaita, A.2    Valdizan, E.M.3    Ledent, C.4    Pazos, A.5    Maldonado, R.6    Valverde, O.7
  • 4
    • 0034044078 scopus 로고    scopus 로고
    • Cannabinoids modulate synaptic strength and plasticity at glutamatergic synapses of rat prefrontal cortex pyramidal neurons
    • Auclair N., Otani S., Soubrie P., Crepel F. Cannabinoids modulate synaptic strength and plasticity at glutamatergic synapses of rat prefrontal cortex pyramidal neurons. J. Neurophysiol. 2000, 83:3287-3293.
    • (2000) J. Neurophysiol. , vol.83 , pp. 3287-3293
    • Auclair, N.1    Otani, S.2    Soubrie, P.3    Crepel, F.4
  • 5
    • 35548980029 scopus 로고    scopus 로고
    • Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex
    • Bambico F.R., Katz N., Debonnel G., Gobbi G. Cannabinoids elicit antidepressant-like behavior and activate serotonergic neurons through the medial prefrontal cortex. J. Neurosci. 2007, 27:11700-11711.
    • (2007) J. Neurosci. , vol.27 , pp. 11700-11711
    • Bambico, F.R.1    Katz, N.2    Debonnel, G.3    Gobbi, G.4
  • 6
    • 0026479453 scopus 로고
    • Architecture and cortical connections of the prefrontal cortex in the rhesus monkey
    • Barbas H. Architecture and cortical connections of the prefrontal cortex in the rhesus monkey. Adv. Neurol. 1992, 57:91-115.
    • (1992) Adv. Neurol. , vol.57 , pp. 91-115
    • Barbas, H.1
  • 7
    • 5344221575 scopus 로고    scopus 로고
    • The role of endogenous cannabinoids in the hypothalamo-pituitary-adrenal axis regulation: in vivo and in vitro studies in CB1 receptor knockout mice
    • Barna I., Zelena D., Arszovszki A.C., Ledent C. The role of endogenous cannabinoids in the hypothalamo-pituitary-adrenal axis regulation: in vivo and in vitro studies in CB1 receptor knockout mice. Life Sci. 2004, 75:2959-2970.
    • (2004) Life Sci. , vol.75 , pp. 2959-2970
    • Barna, I.1    Zelena, D.2    Arszovszki, A.C.3    Ledent, C.4
  • 8
    • 42349088314 scopus 로고    scopus 로고
    • Endogenous cannabinoids: structure and metabolism
    • Bisogno T. Endogenous cannabinoids: structure and metabolism. J. Neuroendocrinol. 2008, 20:1-9.
    • (2008) J. Neuroendocrinol. , vol.20 , pp. 1-9
    • Bisogno, T.1
  • 9
    • 53649087673 scopus 로고    scopus 로고
    • Facilitation of contextual fear memory extinction and anti-anxiogenic effects of AM404 and cannabidiol in conditioned rats
    • Bitencourt R.M., Pamplona F.A., Takahashi R.N. Facilitation of contextual fear memory extinction and anti-anxiogenic effects of AM404 and cannabidiol in conditioned rats. Eur. Neuropsychopharmacol. 2008, 18:849-859.
    • (2008) Eur. Neuropsychopharmacol. , vol.18 , pp. 849-859
    • Bitencourt, R.M.1    Pamplona, F.A.2    Takahashi, R.N.3
  • 10
    • 22544437266 scopus 로고    scopus 로고
    • Endocannabinoid signaling in rat somatosensory cortex: laminar differences and involvement of specific interneuron types
    • Bodor A.L., Katona I., Nyiri G., Mackie K., Ledent C., Hajos N., Freund T.F. Endocannabinoid signaling in rat somatosensory cortex: laminar differences and involvement of specific interneuron types. J. Neurosci. 2005, 25:6845-6856.
    • (2005) J. Neurosci. , vol.25 , pp. 6845-6856
    • Bodor, A.L.1    Katona, I.2    Nyiri, G.3    Mackie, K.4    Ledent, C.5    Hajos, N.6    Freund, T.F.7
  • 11
    • 80053243206 scopus 로고    scopus 로고
    • Cannabis use among military veterans after residential treatment for posttraumatic stress disorder
    • Bonn-Miller M.O., Vujanovic A.A., Drescher K.D. Cannabis use among military veterans after residential treatment for posttraumatic stress disorder. Psychol. Addict. Behav. 2011, 25:485-491.
    • (2011) Psychol. Addict. Behav. , vol.25 , pp. 485-491
    • Bonn-Miller, M.O.1    Vujanovic, A.A.2    Drescher, K.D.3
  • 13
    • 0037084466 scopus 로고    scopus 로고
    • Volumetric reduction in left subgenual prefrontal cortex in early onset depression
    • Botteron K.N., Raichle M.E., Drevets W.C., Heath A.C., Todd R.D. Volumetric reduction in left subgenual prefrontal cortex in early onset depression. Biol. Psychiatry 2002, 51:342-344.
    • (2002) Biol. Psychiatry , vol.51 , pp. 342-344
    • Botteron, K.N.1    Raichle, M.E.2    Drevets, W.C.3    Heath, A.C.4    Todd, R.D.5
  • 14
    • 0035178431 scopus 로고    scopus 로고
    • Cannabis abuse as a risk factor for depressive symptoms
    • Bovasso G.B. Cannabis abuse as a risk factor for depressive symptoms. Am. J. Psychiatry 2001, 158:2033-2037.
    • (2001) Am. J. Psychiatry , vol.158 , pp. 2033-2037
    • Bovasso, G.B.1
  • 15
    • 0036641819 scopus 로고    scopus 로고
    • Rodent models of prefrontal cortical function
    • Brown V.J., Bowman E.M. Rodent models of prefrontal cortical function. Trends Neurosci. 2002, 25:340-343.
    • (2002) Trends Neurosci. , vol.25 , pp. 340-343
    • Brown, V.J.1    Bowman, E.M.2
  • 17
    • 84868122317 scopus 로고    scopus 로고
    • Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders
    • Campos A.C., Moreira F.A., Gomes F.V., Del Bel E.A., Guimaraes F.S. Multiple mechanisms involved in the large-spectrum therapeutic potential of cannabidiol in psychiatric disorders. Philos. Trans. R. Soc. B 2012, 367:3364-3378.
    • (2012) Philos. Trans. R. Soc. B , vol.367 , pp. 3364-3378
    • Campos, A.C.1    Moreira, F.A.2    Gomes, F.V.3    Del Bel, E.A.4    Guimaraes, F.S.5
  • 18
    • 0027933269 scopus 로고
    • Architectonic subdivision of the orbital and medial prefrontal cortex in the macaque monkey
    • Carmichael S.T., Price J.L. Architectonic subdivision of the orbital and medial prefrontal cortex in the macaque monkey. J. Comp. Neurol. 1994, 346:366-402.
    • (1994) J. Comp. Neurol. , vol.346 , pp. 366-402
    • Carmichael, S.T.1    Price, J.L.2
  • 19
    • 0034684023 scopus 로고    scopus 로고
    • Dopamine terminals synapse on callosal projection neurons in the rat prefrontal cortex
    • Carr D.B., Sesack S.R. Dopamine terminals synapse on callosal projection neurons in the rat prefrontal cortex. J. Comp. Neurol. 2000, 425:275-283.
    • (2000) J. Comp. Neurol. , vol.425 , pp. 275-283
    • Carr, D.B.1    Sesack, S.R.2
  • 20
    • 0033770944 scopus 로고    scopus 로고
    • GABA-containing neurons in the rat ventral tegmental area project to the prefrontal cortex
    • Carr D.B., Sesack S.R. GABA-containing neurons in the rat ventral tegmental area project to the prefrontal cortex. Synapse 2000, 38:114-123.
    • (2000) Synapse , vol.38 , pp. 114-123
    • Carr, D.B.1    Sesack, S.R.2
  • 21
    • 33947313358 scopus 로고    scopus 로고
    • The prefrontal cortex as a key target of the maladaptive response to stress
    • Cerqueira J.J., Mailliet F., Almeida O.F., Jay T.M., Sousa N. The prefrontal cortex as a key target of the maladaptive response to stress. J. Neurosci. 2007, 27:2781-2787.
    • (2007) J. Neurosci. , vol.27 , pp. 2781-2787
    • Cerqueira, J.J.1    Mailliet, F.2    Almeida, O.F.3    Jay, T.M.4    Sousa, N.5
  • 22
    • 33947331584 scopus 로고    scopus 로고
    • Specific configuration of dendritic degeneration in pyramidal neurons of the medial prefrontal cortex induced by differing corticosteroid regimens
    • Cerqueira J.J., Taipa R., Uylings H.B., Almeida O.F., Sousa N. Specific configuration of dendritic degeneration in pyramidal neurons of the medial prefrontal cortex induced by differing corticosteroid regimens. Cereb. Cortex 2007, 17:1998-2006.
    • (2007) Cereb. Cortex , vol.17 , pp. 1998-2006
    • Cerqueira, J.J.1    Taipa, R.2    Uylings, H.B.3    Almeida, O.F.4    Sousa, N.5
  • 23
    • 0034506761 scopus 로고    scopus 로고
    • Collateral projection from the amygdalo--hippocampal transition area and CA1 to the hypothalamus and medial prefrontal cortex in the rat
    • Chiba T. Collateral projection from the amygdalo--hippocampal transition area and CA1 to the hypothalamus and medial prefrontal cortex in the rat. Neurosci. Res. 2000, 38:373-383.
    • (2000) Neurosci. Res. , vol.38 , pp. 373-383
    • Chiba, T.1
  • 24
    • 77953044816 scopus 로고    scopus 로고
    • Dopaminergic Modulation of Endocannabinoid-Mediated Plasticity at GABAergic Synapses in the Prefrontal Cortex
    • Chiu C.Q., Puente N., Grandes P., Castillo P.E. Dopaminergic Modulation of Endocannabinoid-Mediated Plasticity at GABAergic Synapses in the Prefrontal Cortex. J. Neurosci. 2010, 30:7236-7248.
    • (2010) J. Neurosci. , vol.30 , pp. 7236-7248
    • Chiu, C.Q.1    Puente, N.2    Grandes, P.3    Castillo, P.E.4
  • 25
    • 84862003296 scopus 로고    scopus 로고
    • Expression pattern of the cannabinoid receptor genes in the frontal cortex of mood disorder patients and mice selectively bred for high and low fear
    • Choi K., Le T., McGuire J., Xing G., Zhang L., Li H., Parker C.C., Johnson L.R., Ursano R.J. Expression pattern of the cannabinoid receptor genes in the frontal cortex of mood disorder patients and mice selectively bred for high and low fear. J. Psychiatr. Res. 2012, 46:882-889.
    • (2012) J. Psychiatr. Res. , vol.46 , pp. 882-889
    • Choi, K.1    Le, T.2    McGuire, J.3    Xing, G.4    Zhang, L.5    Li, H.6    Parker, C.C.7    Johnson, L.R.8    Ursano, R.J.9
  • 26
    • 3442877504 scopus 로고    scopus 로고
    • Chronic stress alters dendritic morphology in rat medial prefrontal cortex
    • Cook S.C., Wellman C.L. Chronic stress alters dendritic morphology in rat medial prefrontal cortex. J. Neurobiol. 2004, 60:236-248.
    • (2004) J. Neurobiol. , vol.60 , pp. 236-248
    • Cook, S.C.1    Wellman, C.L.2
  • 29
    • 0028894469 scopus 로고
    • Pattern and time course of immediate early gene expression in rat brain following acute stress
    • Cullinan W.E., Herman J.P., Battaglia D.F., Akil H., Watson S.J. Pattern and time course of immediate early gene expression in rat brain following acute stress. Neuroscience 1995, 64:477-505.
    • (1995) Neuroscience , vol.64 , pp. 477-505
    • Cullinan, W.E.1    Herman, J.P.2    Battaglia, D.F.3    Akil, H.4    Watson, S.J.5
  • 30
    • 8844286003 scopus 로고    scopus 로고
    • Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates
    • Dalley J.W., Cardinal R.N., Robbins T.W. Prefrontal executive and cognitive functions in rodents: neural and neurochemical substrates. Neurosci. Biobehav. Rev. 2004, 28:771-784.
    • (2004) Neurosci. Biobehav. Rev. , vol.28 , pp. 771-784
    • Dalley, J.W.1    Cardinal, R.N.2    Robbins, T.W.3
  • 31
    • 84883032895 scopus 로고    scopus 로고
    • Involvement of prelimbic medial prefrontal cortex in panic-like elaborated defensive behaviour and innate fear-induced antinociception elicited by GABAA receptor blockade in the dorsomedial and ventromedial hypothalamic nuclei: role of the endocannabinoid CB1 receptor
    • de Freitas R.L., Salgado-Rohner C.J., Hallak J.E., de Souza Crippa J.A., Coimbra N.C. Involvement of prelimbic medial prefrontal cortex in panic-like elaborated defensive behaviour and innate fear-induced antinociception elicited by GABAA receptor blockade in the dorsomedial and ventromedial hypothalamic nuclei: role of the endocannabinoid CB1 receptor. Int. J. Neuropsychopharmacol. 2013, 16:1781-1798.
    • (2013) Int. J. Neuropsychopharmacol. , vol.16 , pp. 1781-1798
    • de Freitas, R.L.1    Salgado-Rohner, C.J.2    Hallak, J.E.3    de Souza Crippa, J.A.4    Coimbra, N.C.5
  • 32
    • 0035961131 scopus 로고    scopus 로고
    • Studies on [H-3]CP-55940 binding in the human central nervous system: Regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use
    • Dean B., Sundram S., Bradbury R., Scarr E., Copolov D. Studies on [H-3]CP-55940 binding in the human central nervous system: Regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use. Neuroscience 2001, 103:9-15.
    • (2001) Neuroscience , vol.103 , pp. 9-15
    • Dean, B.1    Sundram, S.2    Bradbury, R.3    Scarr, E.4    Copolov, D.5
  • 33
    • 50849089964 scopus 로고    scopus 로고
    • Neural circuitry underlying the regulation of conditioned fear and its relation to extinction
    • Delgado M.R., Nearing K.I., LeDoux J.E., Phelps E.A. Neural circuitry underlying the regulation of conditioned fear and its relation to extinction. Neuron 2008, 59:829-838.
    • (2008) Neuron , vol.59 , pp. 829-838
    • Delgado, M.R.1    Nearing, K.I.2    LeDoux, J.E.3    Phelps, E.A.4
  • 35
    • 0032401036 scopus 로고    scopus 로고
    • Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory action
    • Di Marzo V., Melck D., Bisogno T., De Petrocellis L. Endocannabinoids: endogenous cannabinoid receptor ligands with neuromodulatory action. Trends Neurosci. 1999, 21:521-528.
    • (1999) Trends Neurosci. , vol.21 , pp. 521-528
    • Di Marzo, V.1    Melck, D.2    Bisogno, T.3    De Petrocellis, L.4
  • 37
    • 0027200692 scopus 로고
    • The role of the medial prefrontal cortex (cingulate gyrus) in the regulation of hypothalamic-pituitary-adrenal responses to stress
    • Diorio D., Viau V., Meaney M.J. The role of the medial prefrontal cortex (cingulate gyrus) in the regulation of hypothalamic-pituitary-adrenal responses to stress. J. Neurosci. 1993, 13:3839-3847.
    • (1993) J. Neurosci. , vol.13 , pp. 3839-3847
    • Diorio, D.1    Viau, V.2    Meaney, M.J.3
  • 38
    • 0036895345 scopus 로고    scopus 로고
    • Functional anatomical correlates of antidepressant drug treatment assessed using PET measures of regional glucose metabolism
    • Drevets W.C., Bogers W., Raichle M.E. Functional anatomical correlates of antidepressant drug treatment assessed using PET measures of regional glucose metabolism. Eur. Neuropsychopharmacol. 2002, 12:527-544.
    • (2002) Eur. Neuropsychopharmacol. , vol.12 , pp. 527-544
    • Drevets, W.C.1    Bogers, W.2    Raichle, M.E.3
  • 39
    • 0031782081 scopus 로고    scopus 로고
    • Neuroimaging abnormalities in the subgenual prefrontal cortex: implications for the pathophysiology of familial mood disorders
    • 220-226
    • Drevets W.C., Ongur D., Price J.L. Neuroimaging abnormalities in the subgenual prefrontal cortex: implications for the pathophysiology of familial mood disorders. Mol. Psychiatry 1998, 3:190-221. 220-226.
    • (1998) Mol. Psychiatry , vol.3 , pp. 190-221
    • Drevets, W.C.1    Ongur, D.2    Price, J.L.3
  • 40
    • 50249084453 scopus 로고    scopus 로고
    • Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression
    • Drevets W.C., Price J.L., Furey M.L. Brain structural and functional abnormalities in mood disorders: implications for neurocircuitry models of depression. Brain Struct. Funct. 2008, 213:93-118.
    • (2008) Brain Struct. Funct. , vol.213 , pp. 93-118
    • Drevets, W.C.1    Price, J.L.2    Furey, M.L.3
  • 42
    • 50249118405 scopus 로고    scopus 로고
    • The subgenual anterior cingulate cortex in mood disorders
    • Drevets W.C., Savitz J., Trimble M. The subgenual anterior cingulate cortex in mood disorders. CNS Spectr. 2008, 13:663-681.
    • (2008) CNS Spectr. , vol.13 , pp. 663-681
    • Drevets, W.C.1    Savitz, J.2    Trimble, M.3
  • 43
    • 0027181351 scopus 로고
    • Topographic patterns of brain activity in response to swim stress: assessment by 2-deoxyglucose uptake and expression of Fos-like immunoreactivity
    • Duncan G.E., Johnson K.B., Breese G.R. Topographic patterns of brain activity in response to swim stress: assessment by 2-deoxyglucose uptake and expression of Fos-like immunoreactivity. J. Neurosci. 1993, 13:3932-3943.
    • (1993) J. Neurosci. , vol.13 , pp. 3932-3943
    • Duncan, G.E.1    Johnson, K.B.2    Breese, G.R.3
  • 44
    • 0038738350 scopus 로고    scopus 로고
    • Comparative analysis of fatty acid amide hydrolase and CB1 cannabinoid receptor expression in the mouse brain: evidence of a widespread role for fatty acid amide hydrolase in regulation of endocannabinoid signaling
    • Egertova M., Cravatt B.F., Elphick M.R. Comparative analysis of fatty acid amide hydrolase and CB1 cannabinoid receptor expression in the mouse brain: evidence of a widespread role for fatty acid amide hydrolase in regulation of endocannabinoid signaling. Neuroscience 2003, 119:481-496.
    • (2003) Neuroscience , vol.119 , pp. 481-496
    • Egertova, M.1    Cravatt, B.F.2    Elphick, M.R.3
  • 45
    • 33845769902 scopus 로고    scopus 로고
    • Immunocytochemical distribution of the cannabinoid CB1 receptor in the primate neocortex: a regional and laminar analysis
    • Eggan S.M., Lewis D.A. Immunocytochemical distribution of the cannabinoid CB1 receptor in the primate neocortex: a regional and laminar analysis. Cereb. Cortex 2007, 17:175-191.
    • (2007) Cereb. Cortex , vol.17 , pp. 175-191
    • Eggan, S.M.1    Lewis, D.A.2
  • 46
    • 84881547503 scopus 로고    scopus 로고
    • Stress and the developing adolescent brain
    • Eiland L., Romeo R.D. Stress and the developing adolescent brain. Neuroscience 2013, 249:162-171.
    • (2013) Neuroscience , vol.249 , pp. 162-171
    • Eiland, L.1    Romeo, R.D.2
  • 48
    • 0034894593 scopus 로고    scopus 로고
    • The cannabinoid receptor agonist WIN 55,212-2 regulates glutamate transmission in rat cerebral cortex: an in vivo and in vitro study
    • Ferraro L., Tomasini M.C., Gessa G.L., Bebe B.W., Tanganelli S., Antonelli T. The cannabinoid receptor agonist WIN 55,212-2 regulates glutamate transmission in rat cerebral cortex: an in vivo and in vitro study. Cereb. Cortex 2001, 11:728-733.
    • (2001) Cereb. Cortex , vol.11 , pp. 728-733
    • Ferraro, L.1    Tomasini, M.C.2    Gessa, G.L.3    Bebe, B.W.4    Tanganelli, S.5    Antonelli, T.6
  • 49
    • 0242352820 scopus 로고    scopus 로고
    • The medial prefrontal cortex differentially regulates stress-induced c-fos expression in the forebrain depending on type of stressor
    • Figueiredo H.F., Bruestle A., Bodie B., Dolgas C.M., Herman J.P. The medial prefrontal cortex differentially regulates stress-induced c-fos expression in the forebrain depending on type of stressor. Eur. J. Neurosci. 2003, 18:2357-2364.
    • (2003) Eur. J. Neurosci. , vol.18 , pp. 2357-2364
    • Figueiredo, H.F.1    Bruestle, A.2    Bodie, B.3    Dolgas, C.M.4    Herman, J.P.5
  • 50
    • 84861993153 scopus 로고    scopus 로고
    • The endocannabinoid and endovanilloid systems interact in the rat prelimbic medial prefrontal cortex to control anxiety-like behavior
    • Fogaca M.V., Aguiar D.C., Moreira F.A., Guimaraes F.S. The endocannabinoid and endovanilloid systems interact in the rat prelimbic medial prefrontal cortex to control anxiety-like behavior. Neuropharmacology 2012, 63:202-210.
    • (2012) Neuropharmacology , vol.63 , pp. 202-210
    • Fogaca, M.V.1    Aguiar, D.C.2    Moreira, F.A.3    Guimaraes, F.S.4
  • 51
    • 33845745763 scopus 로고    scopus 로고
    • Differential effects of endocannabinoids on glutamatergic and GABAergic inputs to layer 5 pyramidal neurons
    • Fortin D.A., Levine E.S. Differential effects of endocannabinoids on glutamatergic and GABAergic inputs to layer 5 pyramidal neurons. Cereb. Cortex 2007, 17:163-174.
    • (2007) Cereb. Cortex , vol.17 , pp. 163-174
    • Fortin, D.A.1    Levine, E.S.2
  • 52
    • 60349127390 scopus 로고    scopus 로고
    • The use of a synthetic cannabinoid in the management of treatment-resistant nightmares in posttraumatic stress disorder (PTSD)
    • Fraser G.A. The use of a synthetic cannabinoid in the management of treatment-resistant nightmares in posttraumatic stress disorder (PTSD). CNS Neurosci. Ther. 2009, 15:84-88.
    • (2009) CNS Neurosci. Ther. , vol.15 , pp. 84-88
    • Fraser, G.A.1
  • 54
    • 26644446905 scopus 로고    scopus 로고
    • Prefrontal cortex in the rat: projections to subcortical autonomic, motor, and limbic centers
    • Gabbott P.L., Warner T.A., Jays P.R., Salway P., Busby S.J. Prefrontal cortex in the rat: projections to subcortical autonomic, motor, and limbic centers. J. Comp. Neurol. 2005, 492:145-177.
    • (2005) J. Comp. Neurol. , vol.492 , pp. 145-177
    • Gabbott, P.L.1    Warner, T.A.2    Jays, P.R.3    Salway, P.4    Busby, S.J.5
  • 57
    • 33947489961 scopus 로고
    • Isolation, structure, and partial synthesis of an active constituent of hashish
    • Gaoni Y., Mechoulam R. Isolation, structure, and partial synthesis of an active constituent of hashish. J. Am. Chem. Soc. 1964, 86:1646-1647.
    • (1964) J. Am. Chem. Soc. , vol.86 , pp. 1646-1647
    • Gaoni, Y.1    Mechoulam, R.2
  • 58
    • 0025850972 scopus 로고
    • The basal forebrain cholinergic system: efferent and afferent connectivity and long-term effects of lesions
    • Gaykema R.P., Gaal G., Traber J., Hersh L.B., Luiten P.G. The basal forebrain cholinergic system: efferent and afferent connectivity and long-term effects of lesions. Acta Psychiatr. Scand. Suppl. 1991, 366:14-26.
    • (1991) Acta Psychiatr. Scand. Suppl. , vol.366 , pp. 14-26
    • Gaykema, R.P.1    Gaal, G.2    Traber, J.3    Hersh, L.B.4    Luiten, P.G.5
  • 59
    • 33947172809 scopus 로고    scopus 로고
    • Sequence of information processing for emotions based on the anatomic dialogue between prefrontal cortex and amygdala
    • Ghashghaei H., Hilgetag C.C., Barbas H. Sequence of information processing for emotions based on the anatomic dialogue between prefrontal cortex and amygdala. Neuroimage 2007, 34:905-923.
    • (2007) Neuroimage , vol.34 , pp. 905-923
    • Ghashghaei, H.1    Hilgetag, C.C.2    Barbas, H.3
  • 60
    • 0031047273 scopus 로고    scopus 로고
    • Cannabinoid receptors in the human brain: A detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain
    • Glass M., Dragunow M., Faull R.L.M. Cannabinoid receptors in the human brain: A detailed anatomical and quantitative autoradiographic study in the fetal, neonatal and adult human brain. Neuroscience 1997, 77:299-318.
    • (1997) Neuroscience , vol.77 , pp. 299-318
    • Glass, M.1    Dragunow, M.2    Faull, R.L.M.3
  • 63
    • 45849113264 scopus 로고    scopus 로고
    • Regulation of endocannabinoid signaling by stress: implications for stress-related affective disorders
    • Gorzalka B.B., Hill M.N., Hillard C.J. Regulation of endocannabinoid signaling by stress: implications for stress-related affective disorders. Neurosci. Biobehav. Rev. 2008, 32:1152-1160.
    • (2008) Neurosci. Biobehav. Rev. , vol.32 , pp. 1152-1160
    • Gorzalka, B.B.1    Hill, M.N.2    Hillard, C.J.3
  • 64
    • 0032581240 scopus 로고    scopus 로고
    • An electrophysiological and neuroanatomical study of the medial prefrontal cortical projection to the midbrain raphe nuclei in the rat
    • Hajos M., Richards C.D., Szekely A.D., Sharp T. An electrophysiological and neuroanatomical study of the medial prefrontal cortical projection to the midbrain raphe nuclei in the rat. Neuroscience 1998, 87:95-108.
    • (1998) Neuroscience , vol.87 , pp. 95-108
    • Hajos, M.1    Richards, C.D.2    Szekely, A.D.3    Sharp, T.4
  • 65
    • 1842633508 scopus 로고    scopus 로고
    • Context-dependent effects of CB1 cannabinoid gene disruption on anxiety-like and social behaviour in mice
    • Haller J., Varga B., Ledent C., Barna I., Freund T.F. Context-dependent effects of CB1 cannabinoid gene disruption on anxiety-like and social behaviour in mice. Eur. J. Neurosci. 2004, 19:1906-1912.
    • (2004) Eur. J. Neurosci. , vol.19 , pp. 1906-1912
    • Haller, J.1    Varga, B.2    Ledent, C.3    Barna, I.4    Freund, T.F.5
  • 66
    • 77954624619 scopus 로고    scopus 로고
    • Effects of different stimulation parameters on the antidepressant-like response of medial prefrontal cortex deep brain stimulation in rats
    • Hamani C., Diwan M., Isabella S., Lozano A.M., Nobrega J.N. Effects of different stimulation parameters on the antidepressant-like response of medial prefrontal cortex deep brain stimulation in rats. J. Psychiatr. Res. 2010, 44:683-687.
    • (2010) J. Psychiatr. Res. , vol.44 , pp. 683-687
    • Hamani, C.1    Diwan, M.2    Isabella, S.3    Lozano, A.M.4    Nobrega, J.N.5
  • 69
    • 78649369160 scopus 로고    scopus 로고
    • Deep brain stimulation in clinical trials and animal models of depression
    • Hamani C., Nobrega J.N. Deep brain stimulation in clinical trials and animal models of depression. Eur. J. Neurosci. 2010, 32:1109-1117.
    • (2010) Eur. J. Neurosci. , vol.32 , pp. 1109-1117
    • Hamani, C.1    Nobrega, J.N.2
  • 70
    • 77957066928 scopus 로고    scopus 로고
    • Deep brain stimulation in clinical practice and in animal models
    • Hamani C., Nobrega J.N., Lozano A.M. Deep brain stimulation in clinical practice and in animal models. Clin. Pharmacol. Ther. 2010, 88:559-562.
    • (2010) Clin. Pharmacol. Ther. , vol.88 , pp. 559-562
    • Hamani, C.1    Nobrega, J.N.2    Lozano, A.M.3
  • 73
    • 0242383935 scopus 로고    scopus 로고
    • The medial prefrontal cortex in the rat: evidence for a dorso-ventral distinction based upon functional and anatomical characteristics
    • Heidbreder C.A., Groenewegen H.J. The medial prefrontal cortex in the rat: evidence for a dorso-ventral distinction based upon functional and anatomical characteristics. Neurosci. Biobehav. Rev. 2003, 27:555-579.
    • (2003) Neurosci. Biobehav. Rev. , vol.27 , pp. 555-579
    • Heidbreder, C.A.1    Groenewegen, H.J.2
  • 74
    • 79251590548 scopus 로고    scopus 로고
    • Differential developmental trajectories for CB1 cannabinoid receptor expression in limbic/associative and sensorimotor cortical areas
    • Heng L.J., Beverley J.A., Steiner H., Tseng K.Y. Differential developmental trajectories for CB1 cannabinoid receptor expression in limbic/associative and sensorimotor cortical areas. Synapse 2011, 65:278-286.
    • (2011) Synapse , vol.65 , pp. 278-286
    • Heng, L.J.1    Beverley, J.A.2    Steiner, H.3    Tseng, K.Y.4
  • 75
    • 0025954862 scopus 로고
    • Characterization and localization of cannabinoid receptors in rat brain - a quantitative in vitro autoradiographic study
    • Herkenham M., Lynn A.B., Johnson M.R., Melvin L.S., Decosta B.R., Rice K.C. Characterization and localization of cannabinoid receptors in rat brain - a quantitative in vitro autoradiographic study. J. Neurosci. 1991, 11:563-583.
    • (1991) J. Neurosci. , vol.11 , pp. 563-583
    • Herkenham, M.1    Lynn, A.B.2    Johnson, M.R.3    Melvin, L.S.4    Decosta, B.R.5    Rice, K.C.6
  • 78
    • 84888299927 scopus 로고    scopus 로고
    • Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the world trade center attacks
    • Hill M.N., Bierer L.M., Makotkine I., Golier J.A., Galea S., McEwen B.S., Hillard C.J., Yehuda R. Reductions in circulating endocannabinoid levels in individuals with post-traumatic stress disorder following exposure to the world trade center attacks. Psychoneuroendocrinology 2013, 38:2952-2961.
    • (2013) Psychoneuroendocrinology , vol.38 , pp. 2952-2961
    • Hill, M.N.1    Bierer, L.M.2    Makotkine, I.3    Golier, J.A.4    Galea, S.5    McEwen, B.S.6    Hillard, C.J.7    Yehuda, R.8
  • 79
    • 50849142856 scopus 로고    scopus 로고
    • Regional alterations in the endocannabinoid system in an animal model of depression: effects of concurrent antidepressant treatment
    • Hill M.N., Carrier E.J., McLaughlin R.J., Morrish A.C., Meier S.E., Hillard C.J., Gorzalka B.B. Regional alterations in the endocannabinoid system in an animal model of depression: effects of concurrent antidepressant treatment. J. Neurochem. 2008, 106:2322-2336.
    • (2008) J. Neurochem. , vol.106 , pp. 2322-2336
    • Hill, M.N.1    Carrier, E.J.2    McLaughlin, R.J.3    Morrish, A.C.4    Meier, S.E.5    Hillard, C.J.6    Gorzalka, B.B.7
  • 80
    • 26044433145 scopus 로고    scopus 로고
    • Is there a role for the endocannabinoid system in the etiology and treatment of melancholic depression?
    • Hill M.N., Gorzalka B.B. Is there a role for the endocannabinoid system in the etiology and treatment of melancholic depression?. Behav. Pharmacol. 2005, 16:333-352.
    • (2005) Behav. Pharmacol. , vol.16 , pp. 333-352
    • Hill, M.N.1    Gorzalka, B.B.2
  • 82
    • 79959969118 scopus 로고    scopus 로고
    • Alterations in corticolimbic dendritic morphology and emotional behavior in cannabinoid CB1 receptor-deficient mice parallel the effects of chronic stress
    • Hill M.N., Hillard C.J., McEwen B.S. Alterations in corticolimbic dendritic morphology and emotional behavior in cannabinoid CB1 receptor-deficient mice parallel the effects of chronic stress. Cereb. Cortex 2011, 21:2056-2064.
    • (2011) Cereb. Cortex , vol.21 , pp. 2056-2064
    • Hill, M.N.1    Hillard, C.J.2    McEwen, B.S.3
  • 83
    • 57049099128 scopus 로고    scopus 로고
    • Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents
    • Hill M.N., Ho W.S., Hillard C.J., Gorzalka B.B. Differential effects of the antidepressants tranylcypromine and fluoxetine on limbic cannabinoid receptor binding and endocannabinoid contents. J. Neural Transm. 2008, 115:1673-1679.
    • (2008) J. Neural Transm. , vol.115 , pp. 1673-1679
    • Hill, M.N.1    Ho, W.S.2    Hillard, C.J.3    Gorzalka, B.B.4
  • 84
    • 77953713406 scopus 로고    scopus 로고
    • Involvement of the endocannabinoid system in the neurobehavioural effects of stress and glucocorticoids
    • Hill M.N., McEwen B.S. Involvement of the endocannabinoid system in the neurobehavioural effects of stress and glucocorticoids. Prog. Neuropsychopharmacol. Biol. Psychiatry 2010, 34:791-797.
    • (2010) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.34 , pp. 791-797
    • Hill, M.N.1    McEwen, B.S.2
  • 86
    • 70449529389 scopus 로고    scopus 로고
    • Suppression of amygdalar endocannabinoid signaling by stress contributes to activation of the hypothalamic-pituitary-adrenal axis
    • Hill M.N., McLaughlin R.J., Morrish A.C., Viau V., Floresco S.B., Hillard C.J., Gorzalka B.B. Suppression of amygdalar endocannabinoid signaling by stress contributes to activation of the hypothalamic-pituitary-adrenal axis. Neuropsychopharmacology 2009, 34:2733-2745.
    • (2009) Neuropsychopharmacology , vol.34 , pp. 2733-2745
    • Hill, M.N.1    McLaughlin, R.J.2    Morrish, A.C.3    Viau, V.4    Floresco, S.B.5    Hillard, C.J.6    Gorzalka, B.B.7
  • 89
    • 84857140488 scopus 로고    scopus 로고
    • Endocannabinoid signaling, glucocorticoid-mediated negative feedback, and regulation of the hypothalamic-pituitary-adrenal axis
    • Hill M.N., Tasker J.G. Endocannabinoid signaling, glucocorticoid-mediated negative feedback, and regulation of the hypothalamic-pituitary-adrenal axis. Neuroscience 2012, 204:5-16.
    • (2012) Neuroscience , vol.204 , pp. 5-16
    • Hill, M.N.1    Tasker, J.G.2
  • 90
    • 0033998951 scopus 로고    scopus 로고
    • Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol
    • Hillard C.J. Biochemistry and pharmacology of the endocannabinoids arachidonylethanolamide and 2-arachidonylglycerol. Prostaglandins Other Lipid Mediat. 2000, 61:3-18.
    • (2000) Prostaglandins Other Lipid Mediat. , vol.61 , pp. 3-18
    • Hillard, C.J.1
  • 91
  • 93
    • 65249172084 scopus 로고    scopus 로고
    • Stress-induced prefrontal reorganization and executive dysfunction in rodents
    • Holmes A., Wellman C.L. Stress-induced prefrontal reorganization and executive dysfunction in rodents. Neurosci. Biobehav. Rev. 2009, 33:773-783.
    • (2009) Neurosci. Biobehav. Rev. , vol.33 , pp. 773-783
    • Holmes, A.1    Wellman, C.L.2
  • 95
    • 34548560465 scopus 로고    scopus 로고
    • Anatomical analysis of afferent projections to the medial prefrontal cortex in the rat
    • Hoover W.B., Vertes R.P. Anatomical analysis of afferent projections to the medial prefrontal cortex in the rat. Brain Struct. Funct. 2007, 212:149-179.
    • (2007) Brain Struct. Funct. , vol.212 , pp. 149-179
    • Hoover, W.B.1    Vertes, R.P.2
  • 96
    • 0028987880 scopus 로고
    • Pharmacology of cannabinoid receptors
    • Howlett A.C. Pharmacology of cannabinoid receptors. Annu. Rev. Pharmacol. 1995, 35:607-634.
    • (1995) Annu. Rev. Pharmacol. , vol.35 , pp. 607-634
    • Howlett, A.C.1
  • 100
    • 0025870314 scopus 로고
    • Efferent projections of the infralimbic cortex of the rat
    • Hurley K.M., Herbert H., Moga M.M., Saper C.B. Efferent projections of the infralimbic cortex of the rat. J. Comp. Neurol. 1991, 308:249-276.
    • (1991) J. Comp. Neurol. , vol.308 , pp. 249-276
    • Hurley, K.M.1    Herbert, H.2    Moga, M.M.3    Saper, C.B.4
  • 101
    • 0242610914 scopus 로고    scopus 로고
    • Convergence and interaction of hippocampal and amygdalar projections within the prefrontal cortex in the rat
    • Ishikawa A., Nakamura S. Convergence and interaction of hippocampal and amygdalar projections within the prefrontal cortex in the rat. J. Neurosci. 2003, 23:9987-9995.
    • (2003) J. Neurosci. , vol.23 , pp. 9987-9995
    • Ishikawa, A.1    Nakamura, S.2
  • 102
    • 57649183347 scopus 로고    scopus 로고
    • Limbic regulation of hypothalamo-pituitary-adrenocortical function during acute and chronic stress
    • Jankord R., Herman J.P. Limbic regulation of hypothalamo-pituitary-adrenocortical function during acute and chronic stress. Ann. N. Y. Acad. Sci. 2008, 1148:64-73.
    • (2008) Ann. N. Y. Acad. Sci. , vol.1148 , pp. 64-73
    • Jankord, R.1    Herman, J.P.2
  • 103
    • 77951005803 scopus 로고    scopus 로고
    • Cognitive impairment in pain through amygdala-driven prefrontal cortical deactivation
    • Ji G.C., Sun H., Fu Y., Li Z., Pais-Vieira M., Galhardo V., Neugebauer V. Cognitive impairment in pain through amygdala-driven prefrontal cortical deactivation. J. Neurosci. 2010, 30:5451-5464.
    • (2010) J. Neurosci. , vol.30 , pp. 5451-5464
    • Ji, G.C.1    Sun, H.2    Fu, Y.3    Li, Z.4    Pais-Vieira, M.5    Galhardo, V.6    Neugebauer, V.7
  • 104
    • 0030798727 scopus 로고    scopus 로고
    • Activation of locus coeruleus by prefrontal cortex is mediated by excitatory amino acid inputs
    • Jodo E., Aston-Jones G. Activation of locus coeruleus by prefrontal cortex is mediated by excitatory amino acid inputs. Brain Res. 1997, 768:327-332.
    • (1997) Brain Res. , vol.768 , pp. 327-332
    • Jodo, E.1    Aston-Jones, G.2
  • 105
    • 0032032326 scopus 로고    scopus 로고
    • Potent excitatory influence of prefrontal cortex activity on noradrenergic locus coeruleus neurons
    • Jodo E., Chiang C., Aston-Jones G. Potent excitatory influence of prefrontal cortex activity on noradrenergic locus coeruleus neurons. Neuroscience 1998, 83:63-79.
    • (1998) Neuroscience , vol.83 , pp. 63-79
    • Jodo, E.1    Chiang, C.2    Aston-Jones, G.3
  • 106
    • 0032813322 scopus 로고    scopus 로고
    • Electrical stimulation of rat medial prefrontal cortex enhances forebrain serotonin output: implications for electroconvulsive therapy and transcranial magnetic stimulation in depression
    • Juckel G., Mendlin A., Jacobs B.L. Electrical stimulation of rat medial prefrontal cortex enhances forebrain serotonin output: implications for electroconvulsive therapy and transcranial magnetic stimulation in depression. Neuropsychopharmacology 1999, 21:391-398.
    • (1999) Neuropsychopharmacology , vol.21 , pp. 391-398
    • Juckel, G.1    Mendlin, A.2    Jacobs, B.L.3
  • 108
    • 84862677848 scopus 로고    scopus 로고
    • Multiple functions of endocannabinoid signaling in the brain
    • Katona I., Freund T.F. Multiple functions of endocannabinoid signaling in the brain. Annu. Rev. Neurosci. 2012, 35:529-558.
    • (2012) Annu. Rev. Neurosci. , vol.35 , pp. 529-558
    • Katona, I.1    Freund, T.F.2
  • 112
    • 79960358613 scopus 로고    scopus 로고
    • Cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and NMDA receptor associated protein levels
    • Klugmann M., Klippenstein V., Leweke F.M., Spanagel R., Schneider M. Cannabinoid exposure in pubertal rats increases spontaneous ethanol consumption and NMDA receptor associated protein levels. Int. J. Neuropsychopharmacol. 2011, 14:505-517.
    • (2011) Int. J. Neuropsychopharmacol. , vol.14 , pp. 505-517
    • Klugmann, M.1    Klippenstein, V.2    Leweke, F.M.3    Spanagel, R.4    Schneider, M.5
  • 113
    • 58149381443 scopus 로고    scopus 로고
    • Distinct regions of prefrontal cortex mediate resistance and vulnerability to depression
    • Koenigs M., Huey E.D., Calamia M., Raymont V., Tranel D., Grafman J. Distinct regions of prefrontal cortex mediate resistance and vulnerability to depression. J. Neurosci. 2008, 28:12341-12348.
    • (2008) J. Neurosci. , vol.28 , pp. 12341-12348
    • Koenigs, M.1    Huey, E.D.2    Calamia, M.3    Raymont, V.4    Tranel, D.5    Grafman, J.6
  • 114
    • 0021744034 scopus 로고
    • Functions of the frontal cortex of the rat: a comparative review
    • Kolb B. Functions of the frontal cortex of the rat: a comparative review. Brain Res. 1984, 320:65-98.
    • (1984) Brain Res. , vol.320 , pp. 65-98
    • Kolb, B.1
  • 115
    • 84879134579 scopus 로고    scopus 로고
    • Involvement of cannabinoid receptors in the amygdala and prefrontal cortex of rats in fear learning, consolidation, retrieval and extinction
    • Kuhnert S., Meyer C., Koch M. Involvement of cannabinoid receptors in the amygdala and prefrontal cortex of rats in fear learning, consolidation, retrieval and extinction. Behav. Brain Res. 2013, 250:274-284.
    • (2013) Behav. Brain Res. , vol.250 , pp. 274-284
    • Kuhnert, S.1    Meyer, C.2    Koch, M.3
  • 116
    • 40249107796 scopus 로고    scopus 로고
    • Molecular components and functions of the endocannabinoid system in mouse prefrontal cortex
    • Lafourcade M., Elezgarai I., Mato S., Bakiri Y., Grandes P., Manzoni O.J. Molecular components and functions of the endocannabinoid system in mouse prefrontal cortex. PLoS ONE 2007, 2:e709.
    • (2007) PLoS ONE , vol.2
    • Lafourcade, M.1    Elezgarai, I.2    Mato, S.3    Bakiri, Y.4    Grandes, P.5    Manzoni, O.J.6
  • 118
    • 33745800099 scopus 로고    scopus 로고
    • Cannabinoids potentiate emotional learning plasticity in neurons of the medial prefrontal cortex through basolateral amygdala inputs
    • Laviolette S.R., Grace A.A. Cannabinoids potentiate emotional learning plasticity in neurons of the medial prefrontal cortex through basolateral amygdala inputs. J. Neurosci. 2006, 26:6458-6468.
    • (2006) J. Neurosci. , vol.26 , pp. 6458-6468
    • Laviolette, S.R.1    Grace, A.A.2
  • 119
    • 0034076609 scopus 로고    scopus 로고
    • Emotion circuits in the brain
    • LeDoux J.E. Emotion circuits in the brain. Annu. Rev. Neurosci. 2000, 23:155-184.
    • (2000) Annu. Rev. Neurosci. , vol.23 , pp. 155-184
    • LeDoux, J.E.1
  • 120
    • 84857124882 scopus 로고    scopus 로고
    • Timing is everything: evidence for a role of corticolimbic endocannabinoids in modulating hypothalamic-pituitary-adrenal axis activity across developmental periods
    • Lee T.T., Gorzalka B.B. Timing is everything: evidence for a role of corticolimbic endocannabinoids in modulating hypothalamic-pituitary-adrenal axis activity across developmental periods. Neuroscience 2012, 204:17-30.
    • (2012) Neuroscience , vol.204 , pp. 17-30
    • Lee, T.T.1    Gorzalka, B.B.2
  • 121
    • 84881547296 scopus 로고    scopus 로고
    • Age of stress exposure modulates the immediate and sustained effects of repeated stress on corticolimbic cannabinoid CB1 receptor binding in male rats
    • Lee T.T., Hill M.N. Age of stress exposure modulates the immediate and sustained effects of repeated stress on corticolimbic cannabinoid CB1 receptor binding in male rats. Neuroscience 2013, 249:106-114.
    • (2013) Neuroscience , vol.249 , pp. 106-114
    • Lee, T.T.1    Hill, M.N.2
  • 122
    • 84870319187 scopus 로고    scopus 로고
    • Temporal changes in N-acylethanolamine content and metabolism throughout the peri-adolescent period
    • Lee T.T., Hill M.N., Hillard C.J., Gorzalka B.B. Temporal changes in N-acylethanolamine content and metabolism throughout the peri-adolescent period. Synapse 2013, 67:4-10.
    • (2013) Synapse , vol.67 , pp. 4-10
    • Lee, T.T.1    Hill, M.N.2    Hillard, C.J.3    Gorzalka, B.B.4
  • 123
    • 70849116349 scopus 로고    scopus 로고
    • Involvement of the prelimbic prefrontal cortex on cannabidiol-induced attenuation of contextual conditioned fear in rats
    • Lemos J.I., Resstel L.B., Guimaraes F.S. Involvement of the prelimbic prefrontal cortex on cannabidiol-induced attenuation of contextual conditioned fear in rats. Behav. Brain Res. 2010, 207:105-111.
    • (2010) Behav. Brain Res. , vol.207 , pp. 105-111
    • Lemos, J.I.1    Resstel, L.B.2    Guimaraes, F.S.3
  • 124
    • 57749177951 scopus 로고    scopus 로고
    • The role of prefrontal cortex CB1 receptors in the modulation of fear memory
    • Lin H.C., Mao S.C., Su C.L., Gean P.W. The role of prefrontal cortex CB1 receptors in the modulation of fear memory. Cereb. Cortex 2009, 19:165-175.
    • (2009) Cereb. Cortex , vol.19 , pp. 165-175
    • Lin, H.C.1    Mao, S.C.2    Su, C.L.3    Gean, P.W.4
  • 126
    • 33747070540 scopus 로고    scopus 로고
    • Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting
    • Liston C., Miller M.M., Goldwater D.S., Radley J.J., Rocher A.B., Hof P.R., Morrison J.H., McEwen B.S. Stress-induced alterations in prefrontal cortical dendritic morphology predict selective impairments in perceptual attentional set-shifting. J. Neurosci. 2006, 26:7870-7874.
    • (2006) J. Neurosci. , vol.26 , pp. 7870-7874
    • Liston, C.1    Miller, M.M.2    Goldwater, D.S.3    Radley, J.J.4    Rocher, A.B.5    Hof, P.R.6    Morrison, J.H.7    McEwen, B.S.8
  • 127
    • 0021330569 scopus 로고
    • Substantia nigra and ventral tegmental area projections to cortex: topography and collateralization
    • Loughlin S.E., Fallon J.H. Substantia nigra and ventral tegmental area projections to cortex: topography and collateralization. Neuroscience 1984, 11:425-435.
    • (1984) Neuroscience , vol.11 , pp. 425-435
    • Loughlin, S.E.1    Fallon, J.H.2
  • 128
    • 0026670687 scopus 로고
    • Distribution of cannabinoid receptor messenger-RNA in the human brain - an in situ hybridization histochemistry with oligonucleotides
    • Mailleux P., Parmentier M., Vanderhaeghen J.J. Distribution of cannabinoid receptor messenger-RNA in the human brain - an in situ hybridization histochemistry with oligonucleotides. Neurosci. Lett. 1992, 143:200-204.
    • (1992) Neurosci. Lett. , vol.143 , pp. 200-204
    • Mailleux, P.1    Parmentier, M.2    Vanderhaeghen, J.J.3
  • 129
    • 0026560323 scopus 로고
    • Distribution of neuronal cannabinoid receptor in the adult rat brain - a comparative receptor-binding autoradiography and in situ hybridization histochemistry
    • Mailleux P., Vanderhaeghen J.J. Distribution of neuronal cannabinoid receptor in the adult rat brain - a comparative receptor-binding autoradiography and in situ hybridization histochemistry. Neuroscience 1992, 48:655-668.
    • (1992) Neuroscience , vol.48 , pp. 655-668
    • Mailleux, P.1    Vanderhaeghen, J.J.2
  • 131
    • 0033452718 scopus 로고    scopus 로고
    • Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain
    • Marsicano G., Lutz B. Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain. Eur. J. Neurosci. 1999, 11:4213-4225.
    • (1999) Eur. J. Neurosci. , vol.11 , pp. 4213-4225
    • Marsicano, G.1    Lutz, B.2
  • 132
    • 52949106123 scopus 로고    scopus 로고
    • Expression and function of the endocannabinoid system in glial cells
    • Massi P., Valenti M., Bolognini D., Parolaro D. Expression and function of the endocannabinoid system in glial cells. Curr. Pharm. Des. 2008, 14:2289-2298.
    • (2008) Curr. Pharm. Des. , vol.14 , pp. 2289-2298
    • Massi, P.1    Valenti, M.2    Bolognini, D.3    Parolaro, D.4
  • 133
    • 1442348869 scopus 로고    scopus 로고
    • Influence of age, postmortem delay and freezing storage period on cannabinoid receptor density and functionality in human brain
    • Mato S., Pazos A. Influence of age, postmortem delay and freezing storage period on cannabinoid receptor density and functionality in human brain. Neuropharmacology 2004, 46:716-726.
    • (2004) Neuropharmacology , vol.46 , pp. 716-726
    • Mato, S.1    Pazos, A.2
  • 134
    • 77149179753 scopus 로고    scopus 로고
    • Long-term fluoxetine treatment modulates cannabinoid type 1 receptor-mediated inhibition of adenylyl cyclase in the rat prefrontal cortex through 5-hydroxytryptamine(1A) receptor-dependent mechanisms
    • Mato S., Vidal R., Castro E., Diaz A., Pazos A., Valdizan E.M. Long-term fluoxetine treatment modulates cannabinoid type 1 receptor-mediated inhibition of adenylyl cyclase in the rat prefrontal cortex through 5-hydroxytryptamine(1A) receptor-dependent mechanisms. Mol. Pharmacol. 2010, 77:424-434.
    • (2010) Mol. Pharmacol. , vol.77 , pp. 424-434
    • Mato, S.1    Vidal, R.2    Castro, E.3    Diaz, A.4    Pazos, A.5    Valdizan, E.M.6
  • 135
    • 0027492734 scopus 로고
    • Localization of cannabinoid receptor messenger-RNA in rat brain
    • Matsuda L.A., Bonner T.I., Lolait S.J. Localization of cannabinoid receptor messenger-RNA in rat brain. J. Comp. Neurol. 1993, 327:535-550.
    • (1993) J. Comp. Neurol. , vol.327 , pp. 535-550
    • Matsuda, L.A.1    Bonner, T.I.2    Lolait, S.J.3
  • 136
    • 0025325535 scopus 로고
    • Structure of a cannabinoid receptor and functional expression of the cloned cDNA
    • Matsuda L.A., Lolait S.J., Brownstein M.J., Young A.C., Bonner T.I. Structure of a cannabinoid receptor and functional expression of the cloned cDNA. Nature 1990, 346:561-564.
    • (1990) Nature , vol.346 , pp. 561-564
    • Matsuda, L.A.1    Lolait, S.J.2    Brownstein, M.J.3    Young, A.C.4    Bonner, T.I.5
  • 137
    • 0033592673 scopus 로고    scopus 로고
    • Characterization of endogenous serotonin-mediated regulation of dopamine release in the rat prefrontal cortex
    • Matsumoto M., Togashi H., Mori K., Ueno K., Miyamoto A., Yoshioka M. Characterization of endogenous serotonin-mediated regulation of dopamine release in the rat prefrontal cortex. Eur. J. Pharmacol. 1999, 383:39-48.
    • (1999) Eur. J. Pharmacol. , vol.383 , pp. 39-48
    • Matsumoto, M.1    Togashi, H.2    Mori, K.3    Ueno, K.4    Miyamoto, A.5    Yoshioka, M.6
  • 140
    • 33846234579 scopus 로고    scopus 로고
    • Protective and damaging effects of stress mediators: central role of the brain
    • McEwen B.S. Protective and damaging effects of stress mediators: central role of the brain. Dialogues Clin Neurosci 2006, 8:367-381.
    • (2006) Dialogues Clin Neurosci , vol.8 , pp. 367-381
    • McEwen, B.S.1
  • 141
    • 84880008715 scopus 로고    scopus 로고
    • The brain on stress: vulnerability and plasticity of the prefrontal cortex over the life course
    • McEwen B.S., Morrison J.H. The brain on stress: vulnerability and plasticity of the prefrontal cortex over the life course. Neuron 2013, 79:16-29.
    • (2013) Neuron , vol.79 , pp. 16-29
    • McEwen, B.S.1    Morrison, J.H.2
  • 142
    • 73049104151 scopus 로고    scopus 로고
    • Chronic stress- and sex-specific neuromorphological and functional changes in limbic structures
    • McLaughlin K.J., Baran S.E., Conrad C.D. Chronic stress- and sex-specific neuromorphological and functional changes in limbic structures. Mol. Neurobiol. 2009, 40:166-182.
    • (2009) Mol. Neurobiol. , vol.40 , pp. 166-182
    • McLaughlin, K.J.1    Baran, S.E.2    Conrad, C.D.3
  • 143
    • 84896030344 scopus 로고    scopus 로고
    • Role of the endocannabinoid system in etiopathology of major depression
    • CRC Press (Taylor & Francis Group), London, F. López-Muñoz, C. Álamo (Eds.)
    • McLaughlin R.J., Bambico F.R., Gobbi G. Role of the endocannabinoid system in etiopathology of major depression. Frontiers in Neuroscience: Neurobiology of Depression 2011, 205-224. CRC Press (Taylor & Francis Group), London. F. López-Muñoz, C. Álamo (Eds.).
    • (2011) Frontiers in Neuroscience: Neurobiology of Depression , pp. 205-224
    • McLaughlin, R.J.1    Bambico, F.R.2    Gobbi, G.3
  • 145
    • 84867615880 scopus 로고    scopus 로고
    • Upregulation of CB1 receptor binding in the ventromedial prefrontal cortex promotes proactive stress-coping strategies following chronic stress exposure
    • McLaughlin R.J., Hill M.N., Dang S.S., Wainwright S.R., Galea L.A.M., Hillard C.J., Gorzalka B.B. Upregulation of CB1 receptor binding in the ventromedial prefrontal cortex promotes proactive stress-coping strategies following chronic stress exposure. Behav. Brain Res. 2013, 237:333-337.
    • (2013) Behav. Brain Res. , vol.237 , pp. 333-337
    • McLaughlin, R.J.1    Hill, M.N.2    Dang, S.S.3    Wainwright, S.R.4    Galea, L.A.M.5    Hillard, C.J.6    Gorzalka, B.B.7
  • 146
    • 40549104129 scopus 로고    scopus 로고
    • Prenatal stress and subsequent exposure to chronic mild stress influence dendritic spine density and morphology in the rat medial prefrontal cortex
    • Michelsen K.A., van den Hove D.L., Schmitz C., Segers O., Prickaerts J., Steinbusch H.W. Prenatal stress and subsequent exposure to chronic mild stress influence dendritic spine density and morphology in the rat medial prefrontal cortex. BMC Neurosci. 2007, 8:107.
    • (2007) BMC Neurosci. , vol.8 , pp. 107
    • Michelsen, K.A.1    van den Hove, D.L.2    Schmitz, C.3    Segers, O.4    Prickaerts, J.5    Steinbusch, H.W.6
  • 147
    • 0037038369 scopus 로고    scopus 로고
    • Neurons in medial prefrontal cortex signal memory for fear extinction
    • Milad M.R., Quirk G.J. Neurons in medial prefrontal cortex signal memory for fear extinction. Nature 2002, 420:70-74.
    • (2002) Nature , vol.420 , pp. 70-74
    • Milad, M.R.1    Quirk, G.J.2
  • 148
    • 0038182090 scopus 로고    scopus 로고
    • Chronic stress attenuates glucocorticoid negative feedback: involvement of the prefrontal cortex and hippocampus
    • Mizoguchi K., Ishige A., Aburada M., Tabira T. Chronic stress attenuates glucocorticoid negative feedback: involvement of the prefrontal cortex and hippocampus. Neuroscience 2003, 119:887-897.
    • (2003) Neuroscience , vol.119 , pp. 887-897
    • Mizoguchi, K.1    Ishige, A.2    Aburada, M.3    Tabira, T.4
  • 149
    • 50349090159 scopus 로고    scopus 로고
    • Persistent depressive state after chronic stress in rats is accompanied by HPA axis dysregulation and reduced prefrontal dopaminergic neurotransmission
    • Mizoguchi K., Shoji H., Ikeda R., Tanaka Y., Tabira T. Persistent depressive state after chronic stress in rats is accompanied by HPA axis dysregulation and reduced prefrontal dopaminergic neurotransmission. Pharmacol. Biochem. Behav. 2008, 91:170-175.
    • (2008) Pharmacol. Biochem. Behav. , vol.91 , pp. 170-175
    • Mizoguchi, K.1    Shoji, H.2    Ikeda, R.3    Tanaka, Y.4    Tabira, T.5
  • 150
    • 0034652088 scopus 로고    scopus 로고
    • Chronic stress induces impairment of spatial working memory because of prefrontal dopaminergic dysfunction
    • Mizoguchi K., Yuzurihara M., Ishige A., Sasaki H., Chui D.H., Tabira T. Chronic stress induces impairment of spatial working memory because of prefrontal dopaminergic dysfunction. J. Neurosci. 2000, 20:1568-1574.
    • (2000) J. Neurosci. , vol.20 , pp. 1568-1574
    • Mizoguchi, K.1    Yuzurihara, M.2    Ishige, A.3    Sasaki, H.4    Chui, D.H.5    Tabira, T.6
  • 154
    • 34447619511 scopus 로고    scopus 로고
    • Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review
    • Moore T.H., Zammit S., Lingford-Hughes A., Barnes T.R., Jones P.B., Burke M., Lewis G. Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review. Lancet 2007, 370:319-328.
    • (2007) Lancet , vol.370 , pp. 319-328
    • Moore, T.H.1    Zammit, S.2    Lingford-Hughes, A.3    Barnes, T.R.4    Jones, P.B.5    Burke, M.6    Lewis, G.7
  • 155
    • 84857133914 scopus 로고    scopus 로고
    • Cannabinoid type 1 receptors and transient receptor potential vanilloid type 1 channels in fear and anxiety-two sides of one coin?
    • Moreira F.A., Aguiar D.C., Terzian A.L., Guimarães F.S., Wotjak C.T. Cannabinoid type 1 receptors and transient receptor potential vanilloid type 1 channels in fear and anxiety-two sides of one coin?. Neuroscience 2012, 204:186-192.
    • (2012) Neuroscience , vol.204 , pp. 186-192
    • Moreira, F.A.1    Aguiar, D.C.2    Terzian, A.L.3    Guimarães, F.S.4    Wotjak, C.T.5
  • 157
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • Munro S., Thomas K.L., Abushaar M. Molecular characterization of a peripheral receptor for cannabinoids. Nature 1993, 365:61-65.
    • (1993) Nature , vol.365 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abushaar, M.3
  • 158
    • 33646671445 scopus 로고    scopus 로고
    • Cannabinoids modulate spontaneous neuronal activity and evoked inhibition of locus coeruleus noradrenergic neurons
    • Muntoni A.L., Pillolla G., Melis M., Perra S., Gessa G.L., Pistis M. Cannabinoids modulate spontaneous neuronal activity and evoked inhibition of locus coeruleus noradrenergic neurons. Eur. J. Neurosci. 2006, 23:2385-2394.
    • (2006) Eur. J. Neurosci. , vol.23 , pp. 2385-2394
    • Muntoni, A.L.1    Pillolla, G.2    Melis, M.3    Perra, S.4    Gessa, G.L.5    Pistis, M.6
  • 159
    • 84856213018 scopus 로고    scopus 로고
    • Functional anatomy of ventromedial prefrontal cortex: implications for mood and anxiety disorders
    • Myers-Schulz B., Koenigs M. Functional anatomy of ventromedial prefrontal cortex: implications for mood and anxiety disorders. Mol. Psychiatry 2012, 17:132-141.
    • (2012) Mol. Psychiatry , vol.17 , pp. 132-141
    • Myers-Schulz, B.1    Koenigs, M.2
  • 162
    • 33745623410 scopus 로고    scopus 로고
    • Increased cannabinoid receptor density in the posterior cingulate cortex in schizophrenia
    • Newell K.A., Deng C., Huang X.F. Increased cannabinoid receptor density in the posterior cingulate cortex in schizophrenia. Exp. Brain Res. 2006, 172:556-560.
    • (2006) Exp. Brain Res. , vol.172 , pp. 556-560
    • Newell, K.A.1    Deng, C.2    Huang, X.F.3
  • 164
    • 34147173269 scopus 로고    scopus 로고
    • Neuropsychobiological evidence for the functional presence and expression of cannabinoid CB2 receptors in the brain
    • Onaivi E.S. Neuropsychobiological evidence for the functional presence and expression of cannabinoid CB2 receptors in the brain. Neuropsychobiology 2006, 54:231-246.
    • (2006) Neuropsychobiology , vol.54 , pp. 231-246
    • Onaivi, E.S.1
  • 166
    • 0033014121 scopus 로고    scopus 로고
    • A light and electron microscopic study of the CB1 cannabinoid receptor in primate brain
    • Ong W.Y., Mackie K. A light and electron microscopic study of the CB1 cannabinoid receptor in primate brain. Neuroscience 1999, 92:1177-1191.
    • (1999) Neuroscience , vol.92 , pp. 1177-1191
    • Ong, W.Y.1    Mackie, K.2
  • 167
    • 0032573166 scopus 로고    scopus 로고
    • Glial reduction in the subgenual prefrontal cortex in mood disorders
    • Ongur D., Drevets W.C., Price J.L. Glial reduction in the subgenual prefrontal cortex in mood disorders. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:13290-13295.
    • (1998) Proc. Natl. Acad. Sci. U.S.A. , vol.95 , pp. 13290-13295
    • Ongur, D.1    Drevets, W.C.2    Price, J.L.3
  • 168
    • 1942511158 scopus 로고    scopus 로고
    • Architectonic subdivision of the human orbital and medial prefrontal cortex
    • Ongur D., Ferry A.T., Price J.L. Architectonic subdivision of the human orbital and medial prefrontal cortex. J. Comp. Neurol. 2003, 460:425-449.
    • (2003) J. Comp. Neurol. , vol.460 , pp. 425-449
    • Ongur, D.1    Ferry, A.T.2    Price, J.L.3
  • 169
    • 0040246220 scopus 로고    scopus 로고
    • The organization of networks within the orbital and medial prefrontal cortex of rats, monkeys and humans
    • Ongur D., Price J.L. The organization of networks within the orbital and medial prefrontal cortex of rats, monkeys and humans. Cereb. Cortex 2000, 10:206-219.
    • (2000) Cereb. Cortex , vol.10 , pp. 206-219
    • Ongur, D.1    Price, J.L.2
  • 170
    • 20144378367 scopus 로고    scopus 로고
    • Systemic administration of WIN 55,212-2 increases norepinephrine release in the rat frontal cortex
    • Oropeza V.C., Page M.E., Van Bockstaele E.J. Systemic administration of WIN 55,212-2 increases norepinephrine release in the rat frontal cortex. Brain Res. 2005, 1046:45-54.
    • (2005) Brain Res. , vol.1046 , pp. 45-54
    • Oropeza, V.C.1    Page, M.E.2    Van Bockstaele, E.J.3
  • 172
    • 40349092930 scopus 로고    scopus 로고
    • The role of fatty acids in the development and treatment of mood disorders
    • Owen C., Rees A.M., Parker G. The role of fatty acids in the development and treatment of mood disorders. Curr. Opin. Psychiatry 2008, 21:19-24.
    • (2008) Curr. Opin. Psychiatry , vol.21 , pp. 19-24
    • Owen, C.1    Rees, A.M.2    Parker, G.3
  • 173
    • 38049026711 scopus 로고    scopus 로고
    • Local administration of a cannabinoid agonist alters norepinephrine efflux in the rat frontal cortex
    • Page M.E., Oropeza V.C., Van Bockstaele E.J. Local administration of a cannabinoid agonist alters norepinephrine efflux in the rat frontal cortex. Neurosci. Lett. 2008, 431:1-5.
    • (2008) Neurosci. Lett. , vol.431 , pp. 1-5
    • Page, M.E.1    Oropeza, V.C.2    Van Bockstaele, E.J.3
  • 174
    • 80053024234 scopus 로고    scopus 로고
    • Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice
    • Pan B., Wang W., Zhong P., Blankman J.L., Cravatt B.F., Liu Q.S. Alterations of endocannabinoid signaling, synaptic plasticity, learning, and memory in monoacylglycerol lipase knock-out mice. J. Neurosci. 2011, 31:13420-13430.
    • (2011) J. Neurosci. , vol.31 , pp. 13420-13430
    • Pan, B.1    Wang, W.2    Zhong, P.3    Blankman, J.L.4    Cravatt, B.F.5    Liu, Q.S.6
  • 175
    • 84873851437 scopus 로고    scopus 로고
    • Implications of memory modulation for post-traumatic stress and fear disorders
    • Parsons R.G., Ressler K.J. Implications of memory modulation for post-traumatic stress and fear disorders. Nat. Neurosci. 2013, 16:146-153.
    • (2013) Nat. Neurosci. , vol.16 , pp. 146-153
    • Parsons, R.G.1    Ressler, K.J.2
  • 176
    • 85027941560 scopus 로고    scopus 로고
    • Mitigation of post-traumatic stress symptoms by Cannabis resin: a review of the clinical and neurobiological evidence
    • Passie T., Emrich H.M., Karst M., Brandt S.D., Halpern J.H. Mitigation of post-traumatic stress symptoms by Cannabis resin: a review of the clinical and neurobiological evidence. Drug Test Anal. 2012, 4:649-659.
    • (2012) Drug Test Anal. , vol.4 , pp. 649-659
    • Passie, T.1    Emrich, H.M.2    Karst, M.3    Brandt, S.D.4    Halpern, J.H.5
  • 177
    • 33745261630 scopus 로고    scopus 로고
    • Pharmacological evaluation of cannabinoid receptor ligands in a mouse model of anxiety: further evidence for an anxiolytic role for endogenous cannabinoid signaling
    • Patel S., Hillard C.J. Pharmacological evaluation of cannabinoid receptor ligands in a mouse model of anxiety: further evidence for an anxiolytic role for endogenous cannabinoid signaling. J. Pharmacol. Exp. Ther. 2006, 318:304-311.
    • (2006) J. Pharmacol. Exp. Ther. , vol.318 , pp. 304-311
    • Patel, S.1    Hillard, C.J.2
  • 178
    • 9444277292 scopus 로고    scopus 로고
    • Endocannabinoid signaling negatively modulates stress-induced activation of the hypothalamic-pituitary-adrenal axis
    • Patel S., Roelke C.T., Rademacher D.J., Cullinan W.E., Hillard C.J. Endocannabinoid signaling negatively modulates stress-induced activation of the hypothalamic-pituitary-adrenal axis. Endocrinology 2004, 145:5431-5438.
    • (2004) Endocrinology , vol.145 , pp. 5431-5438
    • Patel, S.1    Roelke, C.T.2    Rademacher, D.J.3    Cullinan, W.E.4    Hillard, C.J.5
  • 179
    • 16244398653 scopus 로고    scopus 로고
    • Inhibition of restraint stress-induced neural and behavioural activation by endogenous cannabinoid signalling
    • Patel S., Roelke C.T., Rademacher D.J., Hillard C.J. Inhibition of restraint stress-induced neural and behavioural activation by endogenous cannabinoid signalling. Eur. J. Neurosci. 2005, 21:1057-1069.
    • (2005) Eur. J. Neurosci. , vol.21 , pp. 1057-1069
    • Patel, S.1    Roelke, C.T.2    Rademacher, D.J.3    Hillard, C.J.4
  • 180
    • 84883349535 scopus 로고    scopus 로고
    • Fear learning and memory across adolescent development: hormones and behavior special issue: puberty and adolescence
    • Pattwell S.S., Lee F.S., Casey B.J. Fear learning and memory across adolescent development: hormones and behavior special issue: puberty and adolescence. Horm. Behav. 2013, 64:380-389.
    • (2013) Horm. Behav. , vol.64 , pp. 380-389
    • Pattwell, S.S.1    Lee, F.S.2    Casey, B.J.3
  • 181
    • 4544292021 scopus 로고    scopus 로고
    • Extinction learning in humans: role of the amygdala and vmPFC
    • Phelps E.A., Delgado M.R., Nearing K.I., LeDoux J.E. Extinction learning in humans: role of the amygdala and vmPFC. Neuron 2004, 43:897-905.
    • (2004) Neuron , vol.43 , pp. 897-905
    • Phelps, E.A.1    Delgado, M.R.2    Nearing, K.I.3    LeDoux, J.E.4
  • 182
    • 0037032111 scopus 로고    scopus 로고
    • Delta(9)-tetrahydrocannabinol decreases extracellular GABA and increases extracellular glutamate and dopamine levels in the rat prefrontal cortex: an in vivo microdialysis study
    • Pistis M., Ferraro L., Pira L., Flore G., Tanganelli S., Gessa G.L., Devoto P. Delta(9)-tetrahydrocannabinol decreases extracellular GABA and increases extracellular glutamate and dopamine levels in the rat prefrontal cortex: an in vivo microdialysis study. Brain Res. 2002, 948:155-158.
    • (2002) Brain Res. , vol.948 , pp. 155-158
    • Pistis, M.1    Ferraro, L.2    Pira, L.3    Flore, G.4    Tanganelli, S.5    Gessa, G.L.6    Devoto, P.7
  • 184
    • 0028907956 scopus 로고
    • Do rats have prefrontal cortex? The rose-woolsey-akert program reconsidered
    • Preuss T.M. Do rats have prefrontal cortex? The rose-woolsey-akert program reconsidered. J. Cogn. Neurosci. 1995, 7:1-24.
    • (1995) J. Cogn. Neurosci. , vol.7 , pp. 1-24
    • Preuss, T.M.1
  • 186
    • 84896031805 scopus 로고    scopus 로고
    • Cannabinoid modulation of fear extinction brain circuits: a novel target to advance anxiety treatment
    • PMID: 23829364, June 14 (epub ahead of print)
    • Rabinak C.A., Phan K.L. Cannabinoid modulation of fear extinction brain circuits: a novel target to advance anxiety treatment. Curr. Pharm. Des. 2013, PMID: 23829364, June 14 (epub ahead of print).
    • (2013) Curr. Pharm. Des.
    • Rabinak, C.A.1    Phan, K.L.2
  • 187
    • 37349065102 scopus 로고    scopus 로고
    • Effects of acute and repeated restraint stress on endocannabinoid content in the amygdala, ventral striatum, and medial prefrontal cortex in mice
    • Rademacher D.J., Meier S.E., Shi L.Y., Ho W.S.V., Jarrahian A., Hillard C.J. Effects of acute and repeated restraint stress on endocannabinoid content in the amygdala, ventral striatum, and medial prefrontal cortex in mice. Neuropharmacology 2008, 54:108-116.
    • (2008) Neuropharmacology , vol.54 , pp. 108-116
    • Rademacher, D.J.1    Meier, S.E.2    Shi, L.Y.3    Ho, W.S.V.4    Jarrahian, A.5    Hillard, C.J.6
  • 188
    • 84883315917 scopus 로고    scopus 로고
    • Chronic stress-induced alterations of dendritic spine subtypes predict functional decrements in an hypothalamo-pituitary-adrenal-inhibitory prefrontal circuit
    • Radley J.J., Anderson R.M., Hamilton B.A., Alcock J.A., Romig-Martin S.A. Chronic stress-induced alterations of dendritic spine subtypes predict functional decrements in an hypothalamo-pituitary-adrenal-inhibitory prefrontal circuit. J. Neurosci. 2013, 33:14379-14391.
    • (2013) J. Neurosci. , vol.33 , pp. 14379-14391
    • Radley, J.J.1    Anderson, R.M.2    Hamilton, B.A.3    Alcock, J.A.4    Romig-Martin, S.A.5
  • 189
    • 33845615546 scopus 로고    scopus 로고
    • Regional differentiation of the medial prefrontal cortex in regulating adaptive responses to acute emotional stress
    • Radley J.J., Arias C.M., Sawchenko P.E. Regional differentiation of the medial prefrontal cortex in regulating adaptive responses to acute emotional stress. J. Neurosci. 2006, 26:12967-12976.
    • (2006) J. Neurosci. , vol.26 , pp. 12967-12976
    • Radley, J.J.1    Arias, C.M.2    Sawchenko, P.E.3
  • 190
    • 66749120702 scopus 로고    scopus 로고
    • A discrete GABAergic relay mediates medial prefrontal cortical inhibition of the neuroendocrine stress response
    • Radley J.J., Gosselink K.L., Sawchenko P.E. A discrete GABAergic relay mediates medial prefrontal cortical inhibition of the neuroendocrine stress response. J. Neurosci. 2009, 29:7330-7340.
    • (2009) J. Neurosci. , vol.29 , pp. 7330-7340
    • Radley, J.J.1    Gosselink, K.L.2    Sawchenko, P.E.3
  • 191
    • 23444432520 scopus 로고    scopus 로고
    • Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress
    • Radley J.J., Rocher A.B., Janssen W.G., Hof P.R., McEwen B.S., Morrison J.H. Reversibility of apical dendritic retraction in the rat medial prefrontal cortex following repeated stress. Exp. Neurol. 2005, 196:199-203.
    • (2005) Exp. Neurol. , vol.196 , pp. 199-203
    • Radley, J.J.1    Rocher, A.B.2    Janssen, W.G.3    Hof, P.R.4    McEwen, B.S.5    Morrison, J.H.6
  • 194
    • 79959983796 scopus 로고    scopus 로고
    • A common substrate for prefrontal and hippocampal inhibition of the neuroendocrine stress response
    • Radley J.J., Sawchenko P.E. A common substrate for prefrontal and hippocampal inhibition of the neuroendocrine stress response. J. Neurosci. 2011, 31:9683-9695.
    • (2011) J. Neurosci. , vol.31 , pp. 9683-9695
    • Radley, J.J.1    Sawchenko, P.E.2
  • 195
    • 0344765511 scopus 로고    scopus 로고
    • Stress and emotionality: a multidimensional and genetic approach
    • Ramos A., Mormede P. Stress and emotionality: a multidimensional and genetic approach. Neurosci. Biobehav. Rev. 1998, 22:33-57.
    • (1998) Neurosci. Biobehav. Rev. , vol.22 , pp. 33-57
    • Ramos, A.1    Mormede, P.2
  • 196
    • 67649643797 scopus 로고    scopus 로고
    • Differential effects of chronic unpredictable stress on hippocampal CB1 receptors in male and female rats
    • Reich C.G., Taylor M.E., McCarthy M.M. Differential effects of chronic unpredictable stress on hippocampal CB1 receptors in male and female rats. Behav. Brain Res. 2009, 203:264-269.
    • (2009) Behav. Brain Res. , vol.203 , pp. 264-269
    • Reich, C.G.1    Taylor, M.E.2    McCarthy, M.M.3
  • 197
    • 84867583020 scopus 로고    scopus 로고
    • Biphasic effects of cannabinoids in anxiety responses: CB1 and GABA(B) receptors in the balance of GABAergic and glutamatergic neurotransmission
    • Rey A.A., Purrio M., Viveros M.P., Lutz B. Biphasic effects of cannabinoids in anxiety responses: CB1 and GABA(B) receptors in the balance of GABAergic and glutamatergic neurotransmission. Neuropsychopharmacology 2012, 37:2624-2634.
    • (2012) Neuropsychopharmacology , vol.37 , pp. 2624-2634
    • Rey, A.A.1    Purrio, M.2    Viveros, M.P.3    Lutz, B.4
  • 198
    • 61349092930 scopus 로고    scopus 로고
    • Altered CB1 receptor-signaling in prefrontal cortex from an animal model of depression is reversed by chronic fluoxetine
    • Rodriguez-Gaztelumendi A., Rojo M.L., Pazos A., Diaz A. Altered CB1 receptor-signaling in prefrontal cortex from an animal model of depression is reversed by chronic fluoxetine. J. Neurochem. 2009, 108:1423-1433.
    • (2009) J. Neurochem. , vol.108 , pp. 1423-1433
    • Rodriguez-Gaztelumendi, A.1    Rojo, M.L.2    Pazos, A.3    Diaz, A.4
  • 199
    • 0022375515 scopus 로고
    • Efferent connections of the prelimbic (area 32) and the infralimbic (area 25) cortices: an anterograde tracing study in the cat
    • Room P., Russchen F.T., Groenewegen H.J., Lohman A.H. Efferent connections of the prelimbic (area 32) and the infralimbic (area 25) cortices: an anterograde tracing study in the cat. J. Comp. Neurol. 1985, 242:40-55.
    • (1985) J. Comp. Neurol. , vol.242 , pp. 40-55
    • Room, P.1    Russchen, F.T.2    Groenewegen, H.J.3    Lohman, A.H.4
  • 200
    • 84956876478 scopus 로고
    • The orbitofrontal cortex and its connections with the mediodorsal nucleus in rabbit, sheep and cat
    • Rose J.E., Woolsey C.N. The orbitofrontal cortex and its connections with the mediodorsal nucleus in rabbit, sheep and cat. Res. Publ. Assoc. Res. Nerv. Ment. Dis. 1948, 27:210-232.
    • (1948) Res. Publ. Assoc. Res. Nerv. Ment. Dis. , vol.27 , pp. 210-232
    • Rose, J.E.1    Woolsey, C.N.2
  • 201
    • 0036137952 scopus 로고    scopus 로고
    • Cellular mechanisms of infralimbic and prelimbic prefrontal cortical inhibition and dopaminergic modulation of basolateral amygdala neurons in vivo
    • Rosenkranz J.A., Grace A.A. Cellular mechanisms of infralimbic and prelimbic prefrontal cortical inhibition and dopaminergic modulation of basolateral amygdala neurons in vivo. J. Neurosci. 2002, 22:324-337.
    • (2002) J. Neurosci. , vol.22 , pp. 324-337
    • Rosenkranz, J.A.1    Grace, A.A.2
  • 205
    • 77952877711 scopus 로고    scopus 로고
    • Social isolation and chronic handling alter endocannabinoid signaling and behavioral reactivity to context in adult rats
    • Sciolino N.R., Bortolato M., Eisenstein S.A., Fu J., Oveisi F., Hohmann A.G., Piomelli D. Social isolation and chronic handling alter endocannabinoid signaling and behavioral reactivity to context in adult rats. Neuroscience 2010, 168:371-386.
    • (2010) Neuroscience , vol.168 , pp. 371-386
    • Sciolino, N.R.1    Bortolato, M.2    Eisenstein, S.A.3    Fu, J.4    Oveisi, F.5    Hohmann, A.G.6    Piomelli, D.7
  • 206
    • 79959977058 scopus 로고    scopus 로고
    • Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats
    • Sciolino N.R., Zhou W., Hohmann A.G. Enhancement of endocannabinoid signaling with JZL184, an inhibitor of the 2-arachidonoylglycerol hydrolyzing enzyme monoacylglycerol lipase, produces anxiolytic effects under conditions of high environmental aversiveness in rats. Pharmacol. Res. 2011, 64:226-234.
    • (2011) Pharmacol. Res. , vol.64 , pp. 226-234
    • Sciolino, N.R.1    Zhou, W.2    Hohmann, A.G.3
  • 207
    • 63249118693 scopus 로고    scopus 로고
    • Comparing the prefrontal cortex of rats and primates: insights from electrophysiology
    • Seamans J.K., Lapish C.C., Durstewitz D. Comparing the prefrontal cortex of rats and primates: insights from electrophysiology. Neurotox. Res. 2008, 14:249-262.
    • (2008) Neurotox. Res. , vol.14 , pp. 249-262
    • Seamans, J.K.1    Lapish, C.C.2    Durstewitz, D.3
  • 208
    • 84933672452 scopus 로고    scopus 로고
    • Stress-induced cognitive dysfunction: hormone-neurotransmitter interactions in the prefrontal cortex
    • Shansky R.M., Lipps J. Stress-induced cognitive dysfunction: hormone-neurotransmitter interactions in the prefrontal cortex. Front. Hum. Neurosci. 2013, 7:123.
    • (2013) Front. Hum. Neurosci. , vol.7 , pp. 123
    • Shansky, R.M.1    Lipps, J.2
  • 209
    • 0037183736 scopus 로고    scopus 로고
    • Cellular localization of cannabinoid receptors and activated G-proteins in rat anterior cingulate cortex
    • Sim-Selley L.J., Vogt L.J., Vogt B.A., Childers S.R. Cellular localization of cannabinoid receptors and activated G-proteins in rat anterior cingulate cortex. Life Sci. 2002, 71:2217-2226.
    • (2002) Life Sci. , vol.71 , pp. 2217-2226
    • Sim-Selley, L.J.1    Vogt, L.J.2    Vogt, B.A.3    Childers, S.R.4
  • 210
    • 33947697100 scopus 로고    scopus 로고
    • Biochemistry and pharmacology of endovanilloids
    • Starowicz K., Nigam S., Di Marzo V. Biochemistry and pharmacology of endovanilloids. Pharmacol. Ther. 2007, 114:13-33.
    • (2007) Pharmacol. Ther. , vol.114 , pp. 13-33
    • Starowicz, K.1    Nigam, S.2    Di Marzo, V.3
  • 211
    • 37549022284 scopus 로고    scopus 로고
    • Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice
    • Steiner M.A., Marsicano G., Nestler E.J., Holsboer F., Lutz B., Wotjak C.T. Antidepressant-like behavioral effects of impaired cannabinoid receptor type 1 signaling coincide with exaggerated corticosterone secretion in mice. Psychoneuroendocrinology 2008, 33:54-67.
    • (2008) Psychoneuroendocrinology , vol.33 , pp. 54-67
    • Steiner, M.A.1    Marsicano, G.2    Nestler, E.J.3    Holsboer, F.4    Lutz, B.5    Wotjak, C.T.6
  • 212
    • 49049111067 scopus 로고    scopus 로고
    • Conditional cannabinoid receptor type 1 mutants reveal neuron subpopulation-specific effects on behavioral and neuroendocrine stress responses
    • Steiner M.A., Marsicano G., Wotjak C.T., Lutz B. Conditional cannabinoid receptor type 1 mutants reveal neuron subpopulation-specific effects on behavioral and neuroendocrine stress responses. Psychoneuroendocrinology 2008, 33:1165-1170.
    • (2008) Psychoneuroendocrinology , vol.33 , pp. 1165-1170
    • Steiner, M.A.1    Marsicano, G.2    Wotjak, C.T.3    Lutz, B.4
  • 213
    • 47549095647 scopus 로고    scopus 로고
    • Role of the endocannabinoid system in regulation of the hypothalamic-pituitary-adrenocortical axis
    • Steiner M.A., Wotjak C.T. Role of the endocannabinoid system in regulation of the hypothalamic-pituitary-adrenocortical axis. Prog. Brain Res. 2008, 170:397-432.
    • (2008) Prog. Brain Res. , vol.170 , pp. 397-432
    • Steiner, M.A.1    Wotjak, C.T.2
  • 214
    • 0031681337 scopus 로고    scopus 로고
    • Functional associations among trauma, PTSD, and substance-related disorders
    • Stewart S.H., Pihl R.O., Conrod P.J., Dongier M. Functional associations among trauma, PTSD, and substance-related disorders. Addict. Behav. 1998, 23:797-812.
    • (1998) Addict. Behav. , vol.23 , pp. 797-812
    • Stewart, S.H.1    Pihl, R.O.2    Conrod, P.J.3    Dongier, M.4
  • 215
    • 0036019386 scopus 로고    scopus 로고
    • Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance
    • Sugiura T., Kobayashi Y., Oka S., Waku K. Biosynthesis and degradation of anandamide and 2-arachidonoylglycerol and their possible physiological significance. Prostag. Leukotr. Ess. 2002, 66:173-192.
    • (2002) Prostag. Leukotr. Ess. , vol.66 , pp. 173-192
    • Sugiura, T.1    Kobayashi, Y.2    Oka, S.3    Waku, K.4
  • 217
    • 80855138052 scopus 로고    scopus 로고
    • Reversible gating of endocannabinoid plasticity in the amygdala by chronic stress: a potential role for monoacylglycerol lipase inhibition in the prevention of stress-induced behavioral adaptation
    • Sumislawski J.J., Ramikie T.S., Patel S. Reversible gating of endocannabinoid plasticity in the amygdala by chronic stress: a potential role for monoacylglycerol lipase inhibition in the prevention of stress-induced behavioral adaptation. Neuropsychopharmacology 2011, 36:2750-2761.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 2750-2761
    • Sumislawski, J.J.1    Ramikie, T.S.2    Patel, S.3
  • 218
    • 0025934834 scopus 로고
    • Efferent projections of the infralimbic (area 25) region of the medial prefrontal cortex in the rat: an anterograde tracer PHA-L study
    • Takagishi M., Chiba T. Efferent projections of the infralimbic (area 25) region of the medial prefrontal cortex in the rat: an anterograde tracer PHA-L study. Brain Res. 1991, 566:26-39.
    • (1991) Brain Res. , vol.566 , pp. 26-39
    • Takagishi, M.1    Chiba, T.2
  • 219
    • 0028239231 scopus 로고
    • Increase of extracellular dopamine in the prefrontal cortex: a trait of drugs with antidepressant potential?
    • Tanda G., Carboni E., Frau R., Di Chiara G. Increase of extracellular dopamine in the prefrontal cortex: a trait of drugs with antidepressant potential?. Psychopharmacology 1994, 115:285-288.
    • (1994) Psychopharmacology , vol.115 , pp. 285-288
    • Tanda, G.1    Carboni, E.2    Frau, R.3    Di Chiara, G.4
  • 220
    • 1942517936 scopus 로고    scopus 로고
    • Endocannabinoid signalling selectively targets perisomatic inhibitory inputs to pyramidal neurones in juvenile mouse neocortex
    • Trettel J., Fortin D.A., Levine E.S. Endocannabinoid signalling selectively targets perisomatic inhibitory inputs to pyramidal neurones in juvenile mouse neocortex. J. Physiol. (Lond.) 2004, 556:95-107.
    • (2004) J. Physiol. (Lond.) , vol.556 , pp. 95-107
    • Trettel, J.1    Fortin, D.A.2    Levine, E.S.3
  • 221
    • 84880622031 scopus 로고    scopus 로고
    • The endocannabinoid system as a possible target to treat both the cognitive and emotional features of post-traumatic stress disorder (PTSD)
    • Trezza V., Campolongo P. The endocannabinoid system as a possible target to treat both the cognitive and emotional features of post-traumatic stress disorder (PTSD). Front Behav Neurosci. 2013, 7:100.
    • (2013) Front Behav Neurosci. , vol.7 , pp. 100
    • Trezza, V.1    Campolongo, P.2
  • 222
    • 0031929438 scopus 로고    scopus 로고
    • Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system
    • Tsou K., Brown S., Sanudo-Pena M.C., Mackie K., Walker J.M. Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience 1998, 83:393-411.
    • (1998) Neuroscience , vol.83 , pp. 393-411
    • Tsou, K.1    Brown, S.2    Sanudo-Pena, M.C.3    Mackie, K.4    Walker, J.M.5
  • 224
    • 0025670539 scopus 로고
    • Qualitative and quantitative comparison of the prefrontal cortex in rat and in primates, including humans
    • Uylings H.B., van Eden C.G. Qualitative and quantitative comparison of the prefrontal cortex in rat and in primates, including humans. Prog. Brain Res. 1990, 85:31-62.
    • (1990) Prog. Brain Res. , vol.85 , pp. 31-62
    • Uylings, H.B.1    van Eden, C.G.2
  • 226
    • 0242580988 scopus 로고    scopus 로고
    • Differential projections of the infralimbic and prelimbic cortex in the rat
    • Vertes R.P. Differential projections of the infralimbic and prelimbic cortex in the rat. Synapse 2004, 51:32-58.
    • (2004) Synapse , vol.51 , pp. 32-58
    • Vertes, R.P.1
  • 227
    • 33748471284 scopus 로고    scopus 로고
    • Interactions among the medial prefrontal cortex, hippocampus and midline thalamus in emotional and cognitive processing in the rat
    • Vertes R.P. Interactions among the medial prefrontal cortex, hippocampus and midline thalamus in emotional and cognitive processing in the rat. Neuroscience 2006, 142:1-20.
    • (2006) Neuroscience , vol.142 , pp. 1-20
    • Vertes, R.P.1
  • 228
    • 14644422174 scopus 로고    scopus 로고
    • Elevated levels of endocannabinoids and CB1 receptor-mediated G-protein signaling in the prefrontal cortex of alcoholic suicide
    • Vinod K.Y., Arango V., Xie S., Kassir S.A., Mann J.J., Cooper T.B., Hungund B.L. Elevated levels of endocannabinoids and CB1 receptor-mediated G-protein signaling in the prefrontal cortex of alcoholic suicide. Biol. Psychiatry 2005, 57:480-486.
    • (2005) Biol. Psychiatry , vol.57 , pp. 480-486
    • Vinod, K.Y.1    Arango, V.2    Xie, S.3    Kassir, S.A.4    Mann, J.J.5    Cooper, T.B.6    Hungund, B.L.7
  • 229
    • 33748921976 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptor antagonism modulates plasma corticosterone in rodents
    • Wade M.R., Degroot A., Nomikos G.G. Cannabinoid CB1 receptor antagonism modulates plasma corticosterone in rodents. Eur. J. Pharmacol. 2006, 551:162-167.
    • (2006) Eur. J. Pharmacol. , vol.551 , pp. 162-167
    • Wade, M.R.1    Degroot, A.2    Nomikos, G.G.3
  • 230
    • 84863011182 scopus 로고    scopus 로고
    • Acute restraint stress enhances hippocampal endocannabinoid function via glucocorticoid receptor activation
    • Wang M.N., Hill M.N., Zhang L.H., Gorzalka B.B., Hillard C.J., Alger B.E. Acute restraint stress enhances hippocampal endocannabinoid function via glucocorticoid receptor activation. J. Psychopharmacol. 2012, 26:56-70.
    • (2012) J. Psychopharmacol. , vol.26 , pp. 56-70
    • Wang, M.N.1    Hill, M.N.2    Zhang, L.H.3    Gorzalka, B.B.4    Hillard, C.J.5    Alger, B.E.6
  • 231
    • 76049115531 scopus 로고    scopus 로고
    • Cannabinoid CB1 receptors in rat medial prefrontal cortex are colocalized with calbindin- but not parvalbumin- and calretinin-positive GABAergic neurons
    • Wedzony K., Chocyk A. Cannabinoid CB1 receptors in rat medial prefrontal cortex are colocalized with calbindin- but not parvalbumin- and calretinin-positive GABAergic neurons. Pharmacol. Rep. 2009, 61:1000-1007.
    • (2009) Pharmacol. Rep. , vol.61 , pp. 1000-1007
    • Wedzony, K.1    Chocyk, A.2
  • 232
    • 0035889662 scopus 로고    scopus 로고
    • Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration
    • Wellman C.L. Dendritic reorganization in pyramidal neurons in medial prefrontal cortex after chronic corticosterone administration. J Neurobiol 2001, 49:245-253.
    • (2001) J Neurobiol , vol.49 , pp. 245-253
    • Wellman, C.L.1
  • 233
    • 23844500078 scopus 로고    scopus 로고
    • Chronic mild stress (CMS) revisited: consistency and behavioural-neurobiological concordance in the effects of CMS
    • Willner P. Chronic mild stress (CMS) revisited: consistency and behavioural-neurobiological concordance in the effects of CMS. Neuropsychobiology 2005, 52:90-110.
    • (2005) Neuropsychobiology , vol.52 , pp. 90-110
    • Willner, P.1
  • 235
    • 1642523101 scopus 로고    scopus 로고
    • Selective antagonist [H-3]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophrenia
    • Zavitsanou K., Garrick T., Huang X.F. Selective antagonist [H-3]SR141716A binding to cannabinoid CB1 receptors is increased in the anterior cingulate cortex in schizophrenia. Prog. Neuropsychopharmacol. Biol. Psychiatry 2004, 28:355-360.
    • (2004) Prog. Neuropsychopharmacol. Biol. Psychiatry , vol.28 , pp. 355-360
    • Zavitsanou, K.1    Garrick, T.2    Huang, X.F.3


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