-
1
-
-
0033538537
-
Biosynthesis and inactivation of endocannabinoids: Relevance to their proposed role as neuromodulators
-
Di Marzo V. Biosynthesis and inactivation of endocannabinoids: relevance to their proposed role as neuromodulators. Life Sci. 65:1999;645.
-
(1999)
Life Sci.
, vol.65
, pp. 645
-
-
Di Marzo, V.1
-
2
-
-
0033538561
-
Discovery and characterization of endogenous cannabinoids
-
Martin B.R., Mechoulam R., Razdan R.K. Discovery and characterization of endogenous cannabinoids. Life Sci. 65:1999;573.
-
(1999)
Life Sci.
, vol.65
, pp. 573
-
-
Martin, B.R.1
Mechoulam, R.2
Razdan, R.K.3
-
4
-
-
0033850995
-
Natural and synthetic endocannabinoids and their structure-activity relationships
-
Palmer S.L., Khanolkar A.D., Makriyannis A. Natural and synthetic endocannabinoids and their structure-activity relationships. Curr. Pharm. Des. 6:2000;1381.
-
(2000)
Curr. Pharm. Des.
, vol.6
, pp. 1381
-
-
Palmer, S.L.1
Khanolkar, A.D.2
Makriyannis, A.3
-
5
-
-
0027078685
-
Isolation and structure of a brain constituent that binds to the cannabinoid receptor
-
Devane W.A., Hanus L., Breuer A.et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor. Science. 258:1992;1946.
-
(1992)
Science
, vol.258
, pp. 1946
-
-
Devane, W.A.1
Hanus, L.2
Breuer, A.3
-
6
-
-
0027489995
-
Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor
-
Hanus L., Gopher A., Almog S., Mechoulam R. Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor. J. Med. Chem. 36:1993;3032.
-
(1993)
J. Med. Chem.
, vol.36
, pp. 3032
-
-
Hanus, L.1
Gopher, A.2
Almog, S.3
Mechoulam, R.4
-
7
-
-
0029012014
-
Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors
-
Mechoulam R., Ben-Shabat S., Hanus L.et al. Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors. Biochem. Pharmacol. 50:1995;83.
-
(1995)
Biochem. Pharmacol.
, vol.50
, pp. 83
-
-
Mechoulam, R.1
Ben-Shabat, S.2
Hanus, L.3
-
8
-
-
0028970517
-
2-Arachidonoylglycerol: A possible endogenous cannabinoid receptor ligand in brain
-
Sugiura T., Kondo S., Sukagawa A.et al. 2-Arachidonoylglycerol: a possible endogenous cannabinoid receptor ligand in brain. Biochem. Biophys. Res. Commun. 215:1995;89.
-
(1995)
Biochem. Biophys. Res. Commun.
, vol.215
, pp. 89
-
-
Sugiura, T.1
Kondo, S.2
Sukagawa, A.3
-
10
-
-
18444376760
-
International union of pharmacology classification of cannabinoid receptors
-
in press
-
Howlett AC, Barth F, Bonner TI, et al. International union of pharmacology classification of cannabinoid receptors. Pharmacol Rev, in press.
-
Pharmacol Rev
-
-
Howlett, A.C.1
Barth, F.2
Bonner, T.I.3
-
11
-
-
0028246688
-
(R)-Methanandamide: A chiral novel anandamide possessing higher potency and metabolic stability
-
Abadji V., Lin S., Taha G.et al. (R)-Methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability. J. Med. Chem. 37:1994;1889.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 1889
-
-
Abadji, V.1
Lin, S.2
Taha, G.3
-
12
-
-
0033060910
-
Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1)
-
Hillard C.J., Manna S., Greenberg M.J.et al. Synthesis and characterization of potent and selective agonists of the neuronal cannabinoid receptor (CB1). J. Pharmacol. Exp. Ther. 289:1999;1427.
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.289
, pp. 1427
-
-
Hillard, C.J.1
Manna, S.2
Greenberg, M.J.3
-
14
-
-
0031830516
-
An entourage effect: Inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity
-
Ben-Shabat S., Fride E., Sheskin T.et al. An entourage effect: inactive endogenous fatty acid glycerol esters enhance 2-arachidonoyl-glycerol cannabinoid activity. Eur. J. Pharmacol. 353:1998;23.
-
(1998)
Eur. J. Pharmacol.
, vol.353
, pp. 23
-
-
Ben-Shabat, S.1
Fride, E.2
Sheskin, T.3
-
15
-
-
0030870722
-
A second endogenous cannabinoid that modulates long-term potentiation
-
Stella N., Schweitzer P., Piomelli D. A second endogenous cannabinoid that modulates long-term potentiation. Nature. 388:1997;773.
-
(1997)
Nature
, vol.388
, pp. 773
-
-
Stella, N.1
Schweitzer, P.2
Piomelli, D.3
-
17
-
-
0033965479
-
Neuropharmacology and therapeutic potential of cannabinoids
-
Pertwee R.G. Neuropharmacology and therapeutic potential of cannabinoids. Addict. Biol. 5:2000;37.
-
(2000)
Addict. Biol.
, vol.5
, pp. 37
-
-
Pertwee, R.G.1
-
18
-
-
0035150352
-
Cannabinoid receptors and pain
-
Pertwee R.G. Cannabinoid receptors and pain. Prog. Neurobiol. 63:2001;569.
-
(2001)
Prog. Neurobiol.
, vol.63
, pp. 569
-
-
Pertwee, R.G.1
-
19
-
-
0034929449
-
The endocannabinoid nervous system: Unique opportunities for therapeutic intervention
-
Porter A.C., Felder C.C. The endocannabinoid nervous system: unique opportunities for therapeutic intervention. Pharmacol. Ther. 90:2001;45.
-
(2001)
Pharmacol. Ther.
, vol.90
, pp. 45
-
-
Porter, A.C.1
Felder, C.C.2
-
21
-
-
0032926695
-
The effects of cannabinoids on the brain
-
Ameri A. The effects of cannabinoids on the brain. Prog. Neurobiol. 58:1999;315.
-
(1999)
Prog. Neurobiol.
, vol.58
, pp. 315
-
-
Ameri, A.1
-
22
-
-
1642602474
-
Behavioral effects of cannabinoid agents in animals
-
Chaperon F., Thiébot M.-H. Behavioral effects of cannabinoid agents in animals. Crit. Rev. Neurobiol. 13:1999;243.
-
(1999)
Crit. Rev. Neurobiol.
, vol.13
, pp. 243
-
-
Chaperon, F.1
Thiébot, M.-H.2
-
23
-
-
0022885592
-
Structure-activity relationships in cannabinoids
-
Razdan R.K. Structure-activity relationships in cannabinoids. Pharmacol. Rev. 38:1986;75.
-
(1986)
Pharmacol. Rev.
, vol.38
, pp. 75
-
-
Razdan, R.K.1
-
26
-
-
0035048803
-
Blockade of effects of smoked marijuana by the CBl-selective cannabinoid receptor antagonist SR141716
-
Huestis M.A., Gorelick D.A., Heishman S.J.et al. Blockade of effects of smoked marijuana by the CBl-selective cannabinoid receptor antagonist SR141716. Arch. Gen. Psychiatry. 58:2001;322.
-
(2001)
Arch. Gen. Psychiatry
, vol.58
, pp. 322
-
-
Huestis, M.A.1
Gorelick, D.A.2
Heishman, S.J.3
-
28
-
-
0034942985
-
Cannabinoid receptor agonist and antagonist effects on motor function in normal and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-treated non-human primates
-
Meschler J.P., Howlett A.C., Madras B.K. Cannabinoid receptor agonist and antagonist effects on motor function in normal and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (MPTP)-treated non-human primates. Psychopharmacology. 156:2001;79.
-
(2001)
Psychopharmacology
, vol.156
, pp. 79
-
-
Meschler, J.P.1
Howlett, A.C.2
Madras, B.K.3
-
29
-
-
0015911861
-
9-tetrahydrocannabinol in chimpanzees
-
9-tetrahydrocannabinol in chimpanzees. Science. 179:1973;490.
-
(1973)
Science
, vol.179
, pp. 490
-
-
Ferraro, D.P.1
Grilly, D.M.2
-
30
-
-
0015213721
-
Retrieval of information after use of marihuana
-
Abel E.L. Retrieval of information after use of marihuana. Nature. 231:1971;58.
-
(1971)
Nature
, vol.231
, pp. 58
-
-
Abel, E.L.1
-
31
-
-
0026516004
-
9-Tetrahydrocannabinol discrimination in rats as a model for cannabis intoxication
-
9-Tetrahydrocannabinol discrimination in rats as a model for cannabis intoxication. Neurosci. Biobehav. Rev. 16:1992;55.
-
(1992)
Neurosci. Biobehav. Rev.
, vol.16
, pp. 55
-
-
Balster, R.L.1
Prescott, W.R.2
-
32
-
-
0028961790
-
Discriminative stimulus effects of anandamide in rats
-
Wiley J., Balster R., Martin B.M. Discriminative stimulus effects of anandamide in rats. Eur. J. Pharmacol. 276:1995;49.
-
(1995)
Eur. J. Pharmacol.
, vol.276
, pp. 49
-
-
Wiley, J.1
Balster, R.2
Martin, B.M.3
-
33
-
-
0031415862
-
Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys
-
Wiley J.L., Golden K.M., Ryan W.J., Balster R.L., Razdan R.K., Martin B.R. Evaluation of cannabimimetic discriminative stimulus effects of anandamide and methylated fluoroanandamide in rhesus monkeys. Pharmacol. Biochem. Behav. 58:1997;1139.
-
(1997)
Pharmacol. Biochem. Behav.
, vol.58
, pp. 1139
-
-
Wiley, J.L.1
Golden, K.M.2
Ryan, W.J.3
Balster, R.L.4
Razdan, R.K.5
Martin, B.R.6
-
34
-
-
0029079240
-
Discriminative stimulus effects of CP 55,940 and structurally dissimilar cannabinoids in rats
-
Wiley J.L., Barrett R.L., Lowe J., Balster R.L., Martin B.R. Discriminative stimulus effects of CP 55,940 and structurally dissimilar cannabinoids in rats. Neuropharmacology. 34:1995;669.
-
(1995)
Neuropharmacology
, vol.34
, pp. 669
-
-
Wiley, J.L.1
Barrett, R.L.2
Lowe, J.3
Balster, R.L.4
Martin, B.R.5
-
36
-
-
0025787612
-
Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs
-
Martin B.R., Compton D.R., Thomas B.F.et al. Behavioral, biochemical, and molecular modeling evaluations of cannabinoid analogs. Pharmacol. Biochem. Behav. 40:1991;471.
-
(1991)
Pharmacol. Biochem. Behav.
, vol.40
, pp. 471
-
-
Martin, B.R.1
Compton, D.R.2
Thomas, B.F.3
-
37
-
-
0031935011
-
Assessment of anandamide interaction with the cannabinoid brain receptor: SR 141716A antagonism studies in mice and autoradiographic analysis of receptor binding in rat brain
-
Adams I.B., Compton D.R., Martin B.R. Assessment of anandamide interaction with the cannabinoid brain receptor: SR 141716A antagonism studies in mice and autoradiographic analysis of receptor binding in rat brain. J. Pharmacol. Exp. Ther. 284:1998;1209.
-
(1998)
J. Pharmacol. Exp. Ther.
, vol.284
, pp. 1209
-
-
Adams, I.B.1
Compton, D.R.2
Martin, B.R.3
-
39
-
-
0028129936
-
SR141716A, a potent and selective antagonist of the brain cannabinoid receptor
-
Rinaldi-Carmona M., Barth F., Héaulme M.et al. SR141716A, a potent and selective antagonist of the brain cannabinoid receptor. FEBS Lett. 350:1994;240.
-
(1994)
FEBS Lett.
, vol.350
, pp. 240
-
-
Rinaldi-Carmona, M.1
Barth, F.2
Héaulme, M.3
-
40
-
-
0027444951
-
9-tetrahydrocannabinol on delayed match to sample performance in rats: Alterations in short-term memory associated with changes in task specific firing of hippocampal cells
-
9-tetrahydrocannabinol on delayed match to sample performance in rats: alterations in short-term memory associated with changes in task specific firing of hippocampal cells. J. Pharmacol. Exp. Ther. 264:1993;294.
-
(1993)
J. Pharmacol. Exp. Ther.
, vol.264
, pp. 294
-
-
Heyser, C.J.1
Hampson, R.E.2
Deadwyler, S.A.3
-
42
-
-
0030036308
-
9-Tetrahydrocannabinol impairs spatial memory through a cannabinoid receptor mechanism
-
9-Tetrahydrocannabinol impairs spatial memory through a cannabinoid receptor mechanism. Psychopharmacol. 126:1996;125.
-
(1996)
Psychopharmacol.
, vol.126
, pp. 125
-
-
Lichtman, A.H.1
Martin, B.R.2
-
43
-
-
0034666557
-
SR 141716A enhances spatial memory as assessed in a radial-arm maze task in rats
-
Lichtman A.H. SR 141716A enhances spatial memory as assessed in a radial-arm maze task in rats. Eur. J. Pharmacol. 404:2000;175.
-
(2000)
Eur. J. Pharmacol.
, vol.404
, pp. 175
-
-
Lichtman, A.H.1
-
46
-
-
0031929438
-
Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system
-
Tsou K., Brown S., Sañudo-Peña M.C., Mackie K., Walker J.M. Immunohistochemical distribution of cannabinoid CB1 receptors in the rat central nervous system. Neuroscience. 83:1998;393.
-
(1998)
Neuroscience
, vol.83
, pp. 393
-
-
Tsou, K.1
Brown, S.2
Sañudo-Peña, M.C.3
Mackie, K.4
Walker, J.M.5
-
47
-
-
0033802583
-
Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations
-
Hájos N., Katona I., Naiem S.S.et al. Cannabinoids inhibit hippocampal GABAergic transmission and network oscillations. Eur. J. Neurosci. 12:2000;3239.
-
(2000)
Eur. J. Neurosci.
, vol.12
, pp. 3239
-
-
Hájos, N.1
Katona, I.2
Naiem, S.S.3
-
48
-
-
0034638454
-
GABAergic interneurons are the targets of cannabinoid actions in the human hippocampus
-
Katona I., Sperlágh B., Maglóczky Z.et al. GABAergic interneurons are the targets of cannabinoid actions in the human hippocampus. Neuroscience. 100:2000;797.
-
(2000)
Neuroscience
, vol.100
, pp. 797
-
-
Katona, I.1
Sperlágh, B.2
Maglóczky, Z.3
-
49
-
-
0345621691
-
Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons
-
Katona I., Sperlágh B., Sík A.et al. Presynaptically located CB1 cannabinoid receptors regulate GABA release from axon terminals of specific hippocampal interneurons. J. Neurosci. 19:1999;4544.
-
(1999)
J. Neurosci.
, vol.19
, pp. 4544
-
-
Katona, I.1
Sperlágh, B.2
Sík, A.3
-
50
-
-
0033452718
-
Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain
-
Marsicano G., Lutz B. Expression of the cannabinoid receptor CB1 in distinct neuronal subpopulations in the adult mouse forebrain. Eur. J. Neurosci. 11:1999;4213.
-
(1999)
Eur. J. Neurosci.
, vol.11
, pp. 4213
-
-
Marsicano, G.1
Lutz, B.2
-
51
-
-
0032809458
-
Cannabinoid CB1 receptors are localized primarily on cholecystokinin-containing GABAergic interneurons in the rat hippocampal formation
-
Tsou K., Mackie K., Sañudo-Peña M.C., Walker J.M. Cannabinoid CB1 receptors are localized primarily on cholecystokinin-containing GABAergic interneurons in the rat hippocampal formation. Neuroscience. 93:1999;969.
-
(1999)
Neuroscience
, vol.93
, pp. 969
-
-
Tsou, K.1
Mackie, K.2
Sañudo-Peña, M.C.3
Walker, J.M.4
-
52
-
-
0035112869
-
Ultrastructural localization of the CB1 cannabinoid receptor in m-opioid receptor patches of the rat caudate putamen nucleus
-
Rodríguez J.J., Mackie K., Pickel V.M. Ultrastructural localization of the CB1 cannabinoid receptor in m-opioid receptor patches of the rat caudate putamen nucleus. J. Neurosci. 21:2001;823.
-
(2001)
J. Neurosci.
, vol.21
, pp. 823
-
-
Rodríguez, J.J.1
Mackie, K.2
Pickel, V.M.3
-
53
-
-
0035499974
-
Modulation of transmitter release via presynaptic cannabinoid receptors
-
Schlicker E., Kathman M. Modulation of transmitter release via presynaptic cannabinoid receptors. Trends Pharmacol Sci. 22:2001;565.
-
(2001)
Trends Pharmacol Sci.
, vol.22
, pp. 565
-
-
Schlicker, E.1
Kathman, M.2
-
54
-
-
0033362973
-
Dopamine activation of endogenous cannabinoid signaling in dorsal striatum
-
Giuffrida A., Parsons L.H., Kerr T.M., Rodríguez de Fonseca F., Navarro M., Piomelli D. Dopamine activation of endogenous cannabinoid signaling in dorsal striatum. Nat. Neurosci. 2:1999;358.
-
(1999)
Nat. Neurosci.
, vol.2
, pp. 358
-
-
Giuffrida, A.1
Parsons, L.H.2
Kerr, T.M.3
Rodríguez de Fonseca, F.4
Navarro, M.5
Piomelli, D.6
-
55
-
-
0035888999
-
Cerebellar depolarization-induced suppression of inhibition is mediated by endogenous cannabinoids
-
Kreitzer A.C., Regehr W.G. Cerebellar depolarization-induced suppression of inhibition is mediated by endogenous cannabinoids. J. Neurosci. 21:2001;RC174.
-
(2001)
J. Neurosci.
, vol.21
-
-
Kreitzer, A.C.1
Regehr, W.G.2
-
56
-
-
0035899382
-
Presynaptic inhibition caused by retrograde signal from metabotropic glutamate to cannabinoid receptors
-
Maejima T., Hashimoto K., Yoshida T., Aiba A., Kano M. Presynaptic inhibition caused by retrograde signal from metabotropic glutamate to cannabinoid receptors. Neuron. 31:2001;463.
-
(2001)
Neuron
, vol.31
, pp. 463
-
-
Maejima, T.1
Hashimoto, K.2
Yoshida, T.3
Aiba, A.4
Kano, M.5
-
57
-
-
0035050883
-
Endogenous cannabinoids mediate retrograde signals from depolarized postsynaptic neurons to presynaptic terminals
-
Ohno-Shosaku T., Maejima T., Kano M. Endogenous cannabinoids mediate retrograde signals from depolarized postsynaptic neurons to presynaptic terminals. Neuron. 29:2001;729.
-
(2001)
Neuron
, vol.29
, pp. 729
-
-
Ohno-Shosaku, T.1
Maejima, T.2
Kano, M.3
-
58
-
-
0035902918
-
Receptor-dependent formation of endogenous cannabinoids in cortical neurons
-
Stella N., Piomelli D. Receptor-dependent formation of endogenous cannabinoids in cortical neurons. Eur. J. Pharmacol. 425:2001;189.
-
(2001)
Eur. J. Pharmacol.
, vol.425
, pp. 189
-
-
Stella, N.1
Piomelli, D.2
-
59
-
-
0035967145
-
Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses
-
Wilson R.I., Nicoll R.A. Endogenous cannabinoids mediate retrograde signalling at hippocampal synapses. Nature. 410:2001;588.
-
(2001)
Nature
, vol.410
, pp. 588
-
-
Wilson, R.I.1
Nicoll, R.A.2
-
61
-
-
0033666960
-
The movement of N-arachidonoylethanolamine (anandamide) across cellular membranes
-
Hillard C.J., Jarrahian A. The movement of N-arachidonoylethanolamine (anandamide) across cellular membranes. Chem. Phys. Lipids. 108:2000;123.
-
(2000)
Chem. Phys. Lipids
, vol.108
, pp. 123
-
-
Hillard, C.J.1
Jarrahian, A.2
-
62
-
-
0033610794
-
Anandamide hydrolysis by human cells in culture and brain
-
Maccarrone M., van der Stelt M., Rossi A., Veldink G.A., Vliegenthart J.F.G., Finazzi Agrò A. Anandamide hydrolysis by human cells in culture and brain. J. Biol. Chem. 273:1998;32332.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 32332
-
-
Maccarrone, M.1
Van der Stelt, M.2
Rossi, A.3
Veldink, G.A.4
Vliegenthart, J.F.G.5
Finazzi Agrò, A.6
-
63
-
-
0033545991
-
Structural determinants for recognition and translocation by the anandamide transporter
-
Piomelli D., Beltramo M., Glasnapp S.et al. Structural determinants for recognition and translocation by the anandamide transporter. Proc. Natl. Acad. Sci. USA. 96:1999;5802.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5802
-
-
Piomelli, D.1
Beltramo, M.2
Glasnapp, S.3
-
64
-
-
0033538579
-
Structure-activity relationships of anandamide, an endogenous cannabinoid ligand
-
Khanolkar A.D., Makriyannis A. Structure-activity relationships of anandamide, an endogenous cannabinoid ligand. Life Sci. 65:1999;607.
-
(1999)
Life Sci.
, vol.65
, pp. 607
-
-
Khanolkar, A.D.1
Makriyannis, A.2
-
66
-
-
0032494704
-
A new perspective on cannabinoid signalling: Complementary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain
-
Egertová M., Giang D.K., Cravatt B.F., Elphick M.R. A new perspective on cannabinoid signalling: complementary localization of fatty acid amide hydrolase and the CB1 receptor in rat brain. Proc. R. Soc. Lond. B. 265:1998;2081.
-
(1998)
Proc. R. Soc. Lond. B
, vol.265
, pp. 2081
-
-
Egertová, M.1
Giang, D.K.2
Cravatt, B.F.3
Elphick, M.R.4
-
67
-
-
0032479282
-
35S]GTPγS binding to rat cerebellar membranes correlates with agonist-induced decreases in GDP affinity
-
35S]GTPγS binding to rat cerebellar membranes correlates with agonist-induced decreases in GDP affinity. J. Biol. Chem. 273:1998;16865.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 16865
-
-
Breivogel, C.S.1
Selley, D.E.2
Childers, S.R.3
-
71
-
-
0027315816
-
Anandamide, a brain endogenous compound, interacts specifically with cannabinoid receptors and inhibits adenylate cyclase
-
Vogel Z., Barg J., Levy R., Saya D., Heldman E., Mechoulam R. Anandamide, a brain endogenous compound, interacts specifically with cannabinoid receptors and inhibits adenylate cyclase. J. Neurochem. 61:1993;352.
-
(1993)
J. Neurochem.
, vol.61
, pp. 352
-
-
Vogel, Z.1
Barg, J.2
Levy, R.3
Saya, D.4
Heldman, E.5
Mechoulam, R.6
-
72
-
-
0027932775
-
Cannabinoid receptor binding and agonist activity of amides and esters of arachidonic acid
-
Pinto J.C., Potie F., Rice K.C.et al. Cannabinoid receptor binding and agonist activity of amides and esters of arachidonic acid. Mol. Pharmacol. 46:1994;516.
-
(1994)
Mol. Pharmacol.
, vol.46
, pp. 516
-
-
Pinto, J.C.1
Potie, F.2
Rice, K.C.3
-
73
-
-
0028265784
-
Effects of anandamide on cannabinoid receptors in rat brain membranes
-
Childers S.R., Sexton T., Roy M.B. Effects of anandamide on cannabinoid receptors in rat brain membranes. Biochem. Pharmacol. 47:1994;711.
-
(1994)
Biochem. Pharmacol.
, vol.47
, pp. 711
-
-
Childers, S.R.1
Sexton, T.2
Roy, M.B.3
-
74
-
-
0027185227
-
Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction
-
Felder C.C., Briley E.M., Axelrod J., Simpson J.T., Mackie K., Devane W.A. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction. Proc. Natl. Acad. Sci. USA. 90:1993;7656.
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 7656
-
-
Felder, C.C.1
Briley, E.M.2
Axelrod, J.3
Simpson, J.T.4
Mackie, K.5
Devane, W.A.6
-
75
-
-
0027172274
-
Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells
-
Mackie K., Devane W.A., Hille B. Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells. Mol. Pharmacol. 44:1993;498.
-
(1993)
Mol. Pharmacol.
, vol.44
, pp. 498
-
-
Mackie, K.1
Devane, W.A.2
Hille, B.3
-
77
-
-
0031557711
-
Inhibition by 2-arachidonoylglycerol, a novel type of possible neuromodulator, of the depolarization-induced increase in intracellular free calcium in neuroblastoma × glioma hybrid NG108-15 cells
-
Sugiura T., Kodaka T., Kondo S.et al. Inhibition by 2-arachidonoylglycerol, a novel type of possible neuromodulator, of the depolarization-induced increase in intracellular free calcium in neuroblastoma × glioma hybrid NG108-15 cells. Biochem. Biophys. Res. Commun. 233:1997;207.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.233
, pp. 207
-
-
Sugiura, T.1
Kodaka, T.2
Kondo, S.3
-
78
-
-
0028823316
-
Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor
-
Mackie K., Lai Y., Westenbroek R., Mitchell R. Cannabinoids activate an inwardly rectifying potassium conductance and inhibit Q-type calcium currents in AtT20 cells transfected with rat brain cannabinoid receptor. J. Neurosci. 15:1995;6552.
-
(1995)
J. Neurosci.
, vol.15
, pp. 6552
-
-
Mackie, K.1
Lai, Y.2
Westenbroek, R.3
Mitchell, R.4
-
80
-
-
0031914157
-
Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission
-
Hampson A.J., Bornheim L.M., Scanziani M.et al. Dual effects of anandamide on NMDA receptor-mediated responses and neurotransmission. J. Neurochem. 70:1998;671.
-
(1998)
J. Neurochem.
, vol.70
, pp. 671
-
-
Hampson, A.J.1
Bornheim, L.M.2
Scanziani, M.3
-
82
-
-
0032696104
-
Cannabinoid receptors can activate and inhibit G protein-coupled inwardly rectifying potassium channels in a Xenopus oocyte expression system
-
McAllister S.D., Griffin G., Satin L.S., Abood M.E. Cannabinoid receptors can activate and inhibit G protein-coupled inwardly rectifying potassium channels in a Xenopus oocyte expression system. J. Pharmacol. Exp. Ther. 291:1999;618.
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.291
, pp. 618
-
-
McAllister, S.D.1
Griffin, G.2
Satin, L.S.3
Abood, M.E.4
-
83
-
-
0029586743
-
Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1
-
Bouaboula M., Poinot-Chazel C., Bourrié B.et al. Activation of mitogen-activated protein kinases by stimulation of the central cannabinoid receptor CB1. Biochem. J. 312:1995;637.
-
(1995)
Biochem. J.
, vol.312
, pp. 637
-
-
Bouaboula, M.1
Poinot-Chazel, C.2
Bourrié, B.3
-
84
-
-
0029012765
-
Stimulation of cannabinoid receptor CB1 induces krox-24 expression in human astrocytoma cells
-
Bouaboula M., Bourrié B., Rinaldi-Carmona M., Shire D., Le Fur G., Casellas P. Stimulation of cannabinoid receptor CB1 induces krox-24 expression in human astrocytoma cells. J. Biol. Chem. 270:1995;13973.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 13973
-
-
Bouaboula, M.1
Bourrié, B.2
Rinaldi-Carmona, M.3
Shire, D.4
Le Fur, G.5
Casellas, P.6
-
85
-
-
0032577996
-
Arachidonylethanolamide (AEA) activation of FOS proto-oncogene protein immunoreactivity in the rat brain
-
Patel N.A., Moldow R.L., Patel J.A., Wu G., Chang S.L. Arachidonylethanolamide (AEA) activation of FOS proto-oncogene protein immunoreactivity in the rat brain. Brain Res. 797:1998;225.
-
(1998)
Brain Res.
, vol.797
, pp. 225
-
-
Patel, N.A.1
Moldow, R.L.2
Patel, J.A.3
Wu, G.4
Chang, S.L.5
-
87
-
-
0028883207
-
The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide
-
Wartmann M., Campbell D., Subramanian A., Burstein S.H., Davis R.J. The MAP kinase signal transduction pathway is activated by the endogenous cannabinoid anandamide. FEBS Lett. 359:1995;133.
-
(1995)
FEBS Lett.
, vol.359
, pp. 133
-
-
Wartmann, M.1
Campbell, D.2
Subramanian, A.3
Burstein, S.H.4
Davis, R.J.5
-
88
-
-
0029842102
-
Regulation of a neuronal form of focal adhesion kinase by anandamide
-
Derkinderen P., Toutant M., Burgaya F.et al. Regulation of a neuronal form of focal adhesion kinase by anandamide. Science. 273:1996;1719.
-
(1996)
Science
, vol.273
, pp. 1719
-
-
Derkinderen, P.1
Toutant, M.2
Burgaya, F.3
-
90
-
-
0033538504
-
Effects of cannabinoids on energy metabolism
-
Guzmán M., Sánchez C. Effects of cannabinoids on energy metabolism. Life Sci. 65:1999;657.
-
(1999)
Life Sci.
, vol.65
, pp. 657
-
-
Guzmán, M.1
Sánchez, C.2
-
93
-
-
0033614020
-
Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor: Structure-activity relationship of 2-arachidonoylglycerol ether-linked analogues, and related compounds
-
Sugiura T., Kodaka T., Nakane S.et al. Evidence that the cannabinoid CB1 receptor is a 2-arachidonoylglycerol receptor: structure-activity relationship of 2-arachidonoylglycerol ether-linked analogues, and related compounds. J. Biol. Chem. 274:1999;2794.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 2794
-
-
Sugiura, T.1
Kodaka, T.2
Nakane, S.3
-
94
-
-
0029739799
-
Cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes
-
Stefano G.B., Liu Y., Goligorsky M.S. Cannabinoid receptors are coupled to nitric oxide release in invertebrate immunocytes, microglia, and human monocytes. J. Biol. Chem. 271:1996;19238.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 19238
-
-
Stefano, G.B.1
Liu, Y.2
Goligorsky, M.S.3
-
95
-
-
0032550202
-
Morphine and anandamide coupling to nitric oxide stimulates GnRH and CRF release from rat median eminence: Neurovascular regulation
-
Prevot V., Rialas C.M., Croix D.et al. Morphine and anandamide coupling to nitric oxide stimulates GnRH and CRF release from rat median eminence: neurovascular regulation. Brain Res. 790:1998;236.
-
(1998)
Brain Res.
, vol.790
, pp. 236
-
-
Prevot, V.1
Rialas, C.M.2
Croix, D.3
-
96
-
-
0031749558
-
Antagonism of LPS and IFN-γ induction of iNOS in human saphenous vein endothelium by morphine and anandamide by nitric oxide inhibition of adenylate cyclase
-
Stefano G.B., Salzet M., Magazine H.I., Bilfinger T.V. Antagonism of LPS and IFN-γ induction of iNOS in human saphenous vein endothelium by morphine and anandamide by nitric oxide inhibition of adenylate cyclase. J. Cardiovasc. Pharmacol. 31:1998;813.
-
(1998)
J. Cardiovasc. Pharmacol.
, vol.31
, pp. 813
-
-
Stefano, G.B.1
Salzet, M.2
Magazine, H.I.3
Bilfinger, T.V.4
-
97
-
-
0033007857
-
Morphine and anandamide stimulate intracellular calcium transients in human arterial endothelial cells: Coupling to nitric oxide release
-
Fimiani C., Mattocks D., Cavani F.et al. Morphine and anandamide stimulate intracellular calcium transients in human arterial endothelial cells: coupling to nitric oxide release. Cell. Signal. 11:1999;189.
-
(1999)
Cell. Signal.
, vol.11
, pp. 189
-
-
Fimiani, C.1
Mattocks, D.2
Cavani, F.3
-
99
-
-
0033661798
-
Cannabinoid receptors and the regulation of immune response
-
Berdyshev E.V. Cannabinoid receptors and the regulation of immune response. Chem. Phys. Lipids. 108:2000;169.
-
(2000)
Chem. Phys. Lipids
, vol.108
, pp. 169
-
-
Berdyshev, E.V.1
-
100
-
-
85071436256
-
Marijuana and cannabinoids: Effects on infections, immunity, and AIDS
-
Cabral G.A. Marijuana and cannabinoids: effects on infections, immunity, and AIDS. J. Cannabis Ther. 1:2001;61.
-
(2001)
J. Cannabis Ther.
, vol.1
, pp. 61
-
-
Cabral, G.A.1
-
102
-
-
0033057247
-
Cannabinoid inhibition of the processing of intact lysozyme by macrophages: Evidence for CB2 receptor participation
-
McCoy K.L., Matveyeva M., Carlisle S.J., Cabral G.A. Cannabinoid inhibition of the processing of intact lysozyme by macrophages: evidence for CB2 receptor participation. J. Pharmacol. Exp. Ther. 289:1999;1620.
-
(1999)
J. Pharmacol. Exp. Ther.
, vol.289
, pp. 1620
-
-
McCoy, K.L.1
Matveyeva, M.2
Carlisle, S.J.3
Cabral, G.A.4
-
104
-
-
0034703186
-
In vivo and in vitro treatment with the synthetic cannabinoid CP55,940 decreases the in vitro migration of macrophages in the rat: Involvement of both CB1 and CB2 receptors
-
Sacerdote P., Massi P., Panerai A.E., Parolaro D. In vivo and in vitro treatment with the synthetic cannabinoid CP55,940 decreases the in vitro migration of macrophages in the rat: involvement of both CB1 and CB2 receptors. J. Neuroimmunol. 109:2000;155.
-
(2000)
J. Neuroimmunol.
, vol.109
, pp. 155
-
-
Sacerdote, P.1
Massi, P.2
Panerai, A.E.3
Parolaro, D.4
-
106
-
-
0034235808
-
9-Tetrahydrocannabinol inhibits antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway
-
9-Tetrahydrocannabinol inhibits antitumor immunity by a CB2 receptor-mediated, cytokine-dependent pathway. J. Immunol. 165:2000;373.
-
(2000)
J. Immunol.
, vol.165
, pp. 373
-
-
Zhu, L.X.1
Sharma, S.2
Stolina, M.3
-
107
-
-
0034660138
-
9-Tetrahydrocannabinol treatment suppresses immunity and early IFN-g, IL-12, and IL-12 receptor b2 responses to Legionella pneumophila infection
-
9-Tetrahydrocannabinol treatment suppresses immunity and early IFN-g, IL-12, and IL-12 receptor b2 responses to Legionella pneumophila infection. J. Immunol. 164:2000;6461.
-
(2000)
J. Immunol.
, vol.164
, pp. 6461
-
-
Klein, T.W.1
Newton, C.A.2
Nakachi, N.3
Friedman, H.4
-
108
-
-
0034058250
-
Endocannabinoid 2-arachidonyl glycerol is a full agonist through human type 2 cannabinoid receptor: Antagonism by anandamide
-
Gonsiorek W., Lunn C., Fan X., Narula S., Lundell D., Hipkin R.W. Endocannabinoid 2-arachidonyl glycerol is a full agonist through human type 2 cannabinoid receptor: antagonism by anandamide. Mol. Pharmacol. 57:2000;1045.
-
(2000)
Mol. Pharmacol.
, vol.57
, pp. 1045
-
-
Gonsiorek, W.1
Lunn, C.2
Fan, X.3
Narula, S.4
Lundell, D.5
Hipkin, R.W.6
-
109
-
-
0034614374
-
Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor: Comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells
-
Sugiura T., Kondo S., Kishimoto S.et al. Evidence that 2-arachidonoylglycerol but not N-palmitoylethanolamine or anandamide is the physiological ligand for the cannabinoid CB2 receptor: comparison of the agonistic activities of various cannabinoid receptor ligands in HL-60 cells. J. Biol. Chem. 275:2000;605.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 605
-
-
Sugiura, T.1
Kondo, S.2
Kishimoto, S.3
-
110
-
-
0028789427
-
The peripheral cannabinoid receptor: Adenylate cyclase inhibition and G protein coupling
-
Bayewitch M., Avidor-Reiss T., Levy R., Barg J., Mechoulam R., Vogel Z. The peripheral cannabinoid receptor: adenylate cyclase inhibition and G protein coupling. FEBS Lett. 375:1995;143.
-
(1995)
FEBS Lett.
, vol.375
, pp. 143
-
-
Bayewitch, M.1
Avidor-Reiss, T.2
Levy, R.3
Barg, J.4
Mechoulam, R.5
Vogel, Z.6
-
111
-
-
0029989044
-
Signaling pathway associated with stimulation of CB2 peripheral cannabinoid receptor: Involvement of both mitogen-activated protein kinase and induction of Krox-24 expression
-
Bouaboula M., Poinot-Chazel C., Marchand J.et al. Signaling pathway associated with stimulation of CB2 peripheral cannabinoid receptor: involvement of both mitogen-activated protein kinase and induction of Krox-24 expression. Eur. J. Biochem. 237:1996;704.
-
(1996)
Eur. J. Biochem.
, vol.237
, pp. 704
-
-
Bouaboula, M.1
Poinot-Chazel, C.2
Marchand, J.3
-
113
-
-
0033545866
-
Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice
-
Zimmer A., Zimmer A.M., Hohmann A.G., Herkenham M., Bonner T.I. Increased mortality, hypoactivity, and hypoalgesia in cannabinoid CB1 receptor knockout mice. Proc. Natl. Acad. Sci. USA. 96:1999;5780.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 5780
-
-
Zimmer, A.1
Zimmer, A.M.2
Hohmann, A.G.3
Herkenham, M.4
Bonner, T.I.5
-
116
-
-
0038845604
-
Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors
-
Járai Z., Wagner J.A., Varga K.et al. Cannabinoid-induced mesenteric vasodilation through an endothelial site distinct from CB1 or CB2 receptors. Proc. Natl. Acad. Sci. USA. 96:1999;14136.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 14136
-
-
Járai, Z.1
Wagner, J.A.2
Varga, K.3
-
117
-
-
0032924113
-
Mesenteric vasodilation mediated by endothelial anandamide receptors
-
Wagner J.A., Varga K., Járai Z., Kunos G. Mesenteric vasodilation mediated by endothelial anandamide receptors. Hypertension. 33:1999;429.
-
(1999)
Hypertension
, vol.33
, pp. 429
-
-
Wagner, J.A.1
Varga, K.2
Járai, Z.3
Kunos, G.4
-
118
-
-
0005198873
-
Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein-dependent and G protein-independent
-
Mukhopadhyay S., Chapnick B.M., Howlett A.C. Anandamide-induced vasorelaxation in rabbit aortic rings has two components: G protein-dependent and G protein-independent. Am. J. Physiol. 10:2002;1152.
-
(2002)
Am. J. Physiol.
, vol.10
, pp. 1152
-
-
Mukhopadhyay, S.1
Chapnick, B.M.2
Howlett, A.C.3
-
119
-
-
0033667053
-
Endocannabinoids as cardiovascular modulators
-
Kunos G., Járai Z., Bátkai S. Endocannabinoids as cardiovascular modulators. Chem. Phys. Lipids. 108:2000;159.
-
(2000)
Chem. Phys. Lipids
, vol.108
, pp. 159
-
-
Kunos, G.1
Járai, Z.2
Bátkai, S.3
-
121
-
-
0035843772
-
Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide
-
Calignano A., La Rana G., Piomelli D. Antinociceptive activity of the endogenous fatty acid amide, palmitylethanolamide. Eur. J. Pharmacol. 419:2001;191.
-
(2001)
Eur. J. Pharmacol.
, vol.419
, pp. 191
-
-
Calignano, A.1
La Rana, G.2
Piomelli, D.3
-
122
-
-
0033817453
-
A beneficial aspect of a CB1 cannabinoid receptor antagonist: SR141716A is a potent inhibitor of macrophage infection by the intracellular pathogen Brucella suis
-
Gross A., Terraza A., Marchant J.et al. A beneficial aspect of a CB1 cannabinoid receptor antagonist: SR141716A is a potent inhibitor of macrophage infection by the intracellular pathogen Brucella suis. J. Leukocyte Biol. 67:2000;335.
-
(2000)
J. Leukocyte Biol.
, vol.67
, pp. 335
-
-
Gross, A.1
Terraza, A.2
Marchant, J.3
-
124
-
-
0031051583
-
Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor
-
Sheskin T., Hanus L., Slager J., Vogel Z., Mechoulam R. Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor. J. Med. Chem. 40:1997;659.
-
(1997)
J. Med. Chem.
, vol.40
, pp. 659
-
-
Sheskin, T.1
Hanus, L.2
Slager, J.3
Vogel, Z.4
Mechoulam, R.5
-
125
-
-
0030425575
-
Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): Identification of cannabinoid receptor subtype selective ligands
-
Showalter V.M., Compton D.R., Martin B.R., Abood M.E. Evaluation of binding in a transfected cell line expressing a peripheral cannabinoid receptor (CB2): identification of cannabinoid receptor subtype selective ligands. J. Pharmacol. Exp. Ther. 278:1996;989.
-
(1996)
J. Pharmacol. Exp. Ther.
, vol.278
, pp. 989
-
-
Showalter, V.M.1
Compton, D.R.2
Martin, B.R.3
Abood, M.E.4
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