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Volumn 36, Issue 7, 2011, Pages 1489-1504

Deletion of CB2 cannabinoid receptor induces schizophrenia-related behaviors in mice

Author keywords

cannabinoid; CB2 receptor; schizophrenia; risperidone; pre pulse inhibition; gene expression

Indexed keywords

ALPHA 2C ADRENERGIC RECEPTOR; CANNABINOID 2 RECEPTOR; COCAINE; DOPAMINE 2 RECEPTOR; RISPERIDONE; SEROTONIN 2A RECEPTOR; CATECHOLAMINE RECEPTOR; NEUROLEPTIC AGENT;

EID: 79955983779     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2011.34     Document Type: Article
Times cited : (168)

References (102)
  • 1
    • 11844286960 scopus 로고    scopus 로고
    • Mechanisms of action of second generation antipsychotic drugs in schizophrenia: Insights from brain imaging studies
    • DOI 10.1016/j.eurpsy.2004.11.003, PII S0924933804002676
    • Abi-Dargham A, Laruelle M (2005). Mechanisms of action of second generation antipsychotic drugs in schizophrenia: insights from brain imaging studies. Eur Psychiatry 20: 15-27. (Pubitemid 40092387)
    • (2005) European Psychiatry , vol.20 , Issue.1 , pp. 15-27
    • Abi-Dargham, A.1    Laruelle, M.2
  • 2
    • 79956058875 scopus 로고    scopus 로고
    • Last modified on 2010-06-2 accessed on 19-08-2010. IUPHAR database (IU-PHAR-DB)
    • Abood M, Barth F, Bonner TI, Cabral G, Casellas P, Cravatt BF et al (2010a). Cannabinoid receptors: CB1. Last modified on 2010-06-2. http://www.iuphar-db.org/DATABASE/ObjectDisplayForward? objectId / 56. (accessed on 19-08-2010. IUPHAR database (IU-PHAR-DB)).
    • (2010) Cannabinoid Receptors: CB1
    • Abood, M.1    Barth, F.2    Bonner, T.I.3    Cabral, G.4    Casellas, P.5    Cravatt, B.F.6
  • 3
  • 4
    • 0000735519 scopus 로고
    • Cannabis and schizophrenia. A longitudinal study of Swedish conscripts
    • Andreasson S, Allebeck P, Engstrom A, Rydberg U (1987). Cannabis and schizophrenia. A longitudinal study of Swedish conscripts. Lancet 2: 1483-1486.
    • (1987) Lancet , vol.2 , pp. 1483-1486
    • Andreasson, S.1    Allebeck, P.2    Engstrom, A.3    Rydberg, U.4
  • 5
    • 77952623444 scopus 로고    scopus 로고
    • CB2: A cannabinoid receptor with an identity crisis
    • Atwood BK, Mackie K (2010). CB2: a cannabinoid receptor with an identity crisis. Br J Pharmacol 160: 467-479.
    • (2010) Br J Pharmacol , vol.160 , pp. 467-479
    • Atwood, B.K.1    MacKie, K.2
  • 6
    • 71049143223 scopus 로고    scopus 로고
    • Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level
    • Barbier E, Wang J (2009). Anti-depressant and anxiolytic like behaviors in PKCI/HINT1 knockout mice associated with elevated plasma corticosterone level. BMC Neuroscience 10: 132.
    • (2009) BMC Neuroscience , vol.10 , pp. 132
    • Barbier, E.1    Wang, J.2
  • 7
    • 34447521677 scopus 로고    scopus 로고
    • Supersensitivity to amphetamine in protein kinase-C interacting protein/HINT1 knockout mice
    • DOI 10.1038/sj.npp.1301301, PII 1301301
    • Barbier E, Zapata A, Oh E, Liu Q, Zhu F, Undie A et al (2007). Supersensitivity to amphetamine in protein kinase-C interacting protein//HINT1 knockout mice. Neuropsychopharmacology 32: 1774-1782. (Pubitemid 47076381)
    • (2007) Neuropsychopharmacology , vol.32 , Issue.8 , pp. 1774-1782
    • Barbier, E.1    Zapata, A.2    Oh, E.3    Liu, Q.4    Zhu, F.5    Undie, A.6    Shippenberg, T.7    Wang, J.B.8
  • 9
    • 84954358666 scopus 로고    scopus 로고
    • The stop null mice model for schizophrenia displays cognitive and social deficits partly alleviated by neuroleptics
    • Bégou M, Volle J, Bertrand JB, Brun P, Job D, Schweitzer A et al (2008). The stop null mice model for schizophrenia displays cognitive and social deficits partly alleviated by neuroleptics. Neuroscience 157: 29-39.
    • (2008) Neuroscience , vol.157 , pp. 29-39
    • Bégou, M.1    Volle, J.2    Bertrand, J.B.3    Brun, P.4    Job, D.5    Schweitzer, A.6
  • 12
    • 0034891977 scopus 로고    scopus 로고
    • Human studies of prepulse inhibition of startle: Normal subjects, patient groups, and pharmacological studies
    • DOI 10.1007/s002130100810
    • Braff D, Geyer M, Swerdlow N (2001). Human studies of prepulse inhibition of startle: normal subjects, patient groups, and pharmacological studies. Psychopharmacology 156: 234-258. (Pubitemid 32705488)
    • (2001) Psychopharmacology , vol.156 , Issue.2-3 , pp. 234-258
    • Braff, D.L.1    Geyer, M.A.2    Swerdlow, N.R.3
  • 13
    • 0030810919 scopus 로고    scopus 로고
    • The effects of antipsychotic drugs on the mRNA levels of serotonin 5HT(2A) and 5HT(2C) receptors
    • DOI 10.1016/S0169-328X(97)00076-4, PII S0169328X97000764
    • Buckland PR, D'Souza U, Maher NA, McGuffin P (1997). The effects of antipsychotic drugs on the mRNA levels of serotonin 5HT2A and 5HT2C receptors. Mol Brain Res 48: 45-52. (Pubitemid 27298127)
    • (1997) Molecular Brain Research , vol.48 , Issue.1 , pp. 45-52
    • Buckland, P.R.1    D'Souza, U.2    Maher, N.A.3    McGuffin, P.4
  • 15
    • 0029891621 scopus 로고    scopus 로고
    • The effects of clozapine and haloperidol on serotonin-1A, -2A and -2C receptor gene expression and serotonin metabolism in the rat forebrain
    • DOI 10.1016/0306-4522(96)00062-0
    • Burnet PWJ, Chen CPLH, McGowan S, Franklin M, Harrison PJ (1996). The effects of clozapine and haloperidol on serotonin-1A, -2A and -2C receptor gene expression and serotonin metabolism in the rat forebrain. Neuroscience 73: 531-540. (Pubitemid 26168807)
    • (1996) Neuroscience , vol.73 , Issue.2 , pp. 531-540
    • Burnet, P.W.J.1    Chen, C.P.L.-H.2    McGowan, S.3    Franklin, M.4    Harrison, P.J.5
  • 16
    • 0019199013 scopus 로고
    • Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiazepines
    • DOI 10.1016/0091-3057(80)90067-2
    • Crawley J, Goodwin FK (1980). Preliminary report of a simple animal behavior model for the anxiolytic effects of benzodiaze-pines. Pharmacol Biochem Behav 13: 167-170. (Pubitemid 11225713)
    • (1980) Pharmacology Biochemistry and Behavior , vol.13 , Issue.2 , pp. 167-170
    • Crawley, J.1    Goodwin, F.K.2
  • 19
    • 0035961131 scopus 로고    scopus 로고
    • 3H]CP-55940 binding in the human central nervous system: Regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use
    • DOI 10.1016/S0306-4522(00)00552-2, PII S0306452200005522
    • 3H]CP-55940 binding in the human central nervous system: regional specific changes in density of cannabinoid-1 receptors associated with schizophrenia and cannabis use. Neuroscience 103: 9-15. (Pubitemid 32304342)
    • (2001) Neuroscience , vol.103 , Issue.1 , pp. 9-15
    • Dean, B.1    Sundram, S.2    Bradbury, R.3    Scarr, E.4    Copolov, D.D.5
  • 20
    • 72649085418 scopus 로고    scopus 로고
    • Chronic administration of atypical antipsychotics improves behavioral and synaptic defects of STOP null mice
    • Delotterie D, Ruiz G, Brocard J, Schweitzer A, Roucard C, Roche Y et al (2010). Chronic administration of atypical antipsychotics improves behavioral and synaptic defects of STOP null mice. Psychopharmacology 208: 131-141.
    • (2010) Psychopharmacology , vol.208 , pp. 131-141
    • Delotterie, D.1    Ruiz, G.2    Brocard, J.3    Schweitzer, A.4    Roucard, C.5    Roche, Y.6
  • 21
    • 59749104982 scopus 로고    scopus 로고
    • Mutant models for genes associated with schizophrenia
    • Desbonnet L, Waddington JL, O'Tuathaigh CMP (2009). Mutant models for genes associated with schizophrenia. Biochem Soc Trans 037: 308-312.
    • (2009) Biochem Soc Trans , vol.37 , pp. 308-312
    • Desbonnet, L.1    Waddington, J.L.2    Cmp, O.3
  • 22
    • 67650441745 scopus 로고    scopus 로고
    • Behavioral abnormalities in synapsin II knockout mice implicate a causal factor in schizophrenia
    • Dyck BA, Skoblenick KJ, Castellano JM, Ki K, Thomas N, Mishra RK (2009). Behavioral abnormalities in synapsin II knockout mice implicate a causal factor in schizophrenia. Synapse 63: 662-672.
    • (2009) Synapse , vol.63 , pp. 662-672
    • Dyck, B.A.1    Skoblenick, K.J.2    Castellano, J.M.3    Ki, K.4    Thomas, N.5    Mishra, R.K.6
  • 26
    • 0033555898 scopus 로고    scopus 로고
    • Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity
    • Gainetdinov RR, Wetsel WC, Jones SR, Levin ED, Jaber M, Caron MG (1999). Role of serotonin in the paradoxical calming effect of psychostimulants on hyperactivity. Science 283: 397-401.
    • (1999) Science , vol.283 , pp. 397-401
    • Gainetdinov, R.R.1    Wetsel, W.C.2    Jones, S.R.3    Levin, E.D.4    Jaber, M.5    Caron, M.G.6
  • 27
    • 52949118833 scopus 로고    scopus 로고
    • Mechanisms of control of neuron survival by the endocannabi-noid system
    • Galve-Roperh I, Aguado T, Palazuelos J, Guzman M (2008). Mechanisms of control of neuron survival by the endocannabi-noid system. Curr Pharm Des 14: 2279-2288.
    • (2008) Curr Pharm des , vol.14 , pp. 2279-2288
    • Galve-Roperh, I.1    Aguado, T.2    Palazuelos, J.3    Guzman, M.4
  • 28
    • 78650595351 scopus 로고    scopus 로고
    • Overexpression of CB2 cannabinoid receptor gene decreased vulnerability to anxiety and impaired anxiolytic action of alprazolam in mice
    • Garća-Gutiérrez MS, Manzanares J (2011). Overexpression of CB2 cannabinoid receptor gene decreased vulnerability to anxiety and impaired anxiolytic action of alprazolam in mice. J Psychopharmcol 25: 111-120.
    • (2011) J Psychopharmcol , vol.25 , pp. 111-120
    • Garća-Gutiérrez, M.S.1    Manzanares, J.2
  • 30
    • 36549030432 scopus 로고    scopus 로고
    • Evidence of Disrupted Prepulse Inhibition in Unaffected Siblings of Bipolar Disorder Patients
    • DOI 10.1016/j.biopsych.2006.12.002, PII S0006322306015538
    • Giakoumaki SG, Roussos P, Rogdaki M, Karli C, Bitsios P, Frangou S (2007). Evidence of disrupted prepulse inhibition in unaffected siblings of bipolar disorder patients. Biol Psychiatry 62: 1418-1422. (Pubitemid 350180720)
    • (2007) Biological Psychiatry , vol.62 , Issue.12 , pp. 1418-1422
    • Giakoumaki, S.G.1    Roussos, P.2    Rogdaki, M.3    Karli, C.4    Bitsios, P.5    Frangou, S.6
  • 32
    • 47749088572 scopus 로고    scopus 로고
    • A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner
    • Goncalves MB, Suetterlin P, Yip P, Molina-Holgado F, Walker DJ, Oudin MJ et al (2008). A diacylglycerol lipase-CB2 cannabinoid pathway regulates adult subventricular zone neurogenesis in an age-dependent manner. Mol Cell Neurosci 38: 526-536.
    • (2008) Mol Cell Neurosci , vol.38 , pp. 526-536
    • Goncalves, M.B.1    Suetterlin, P.2    Yip, P.3    Molina-Holgado, F.4    Walker, D.J.5    Oudin, M.J.6
  • 33
    • 32844465920 scopus 로고    scopus 로고
    • Cannabinoid CB2 receptors: Immunohistochemical localization in rat brain
    • DOI 10.1016/j.brainres.2005.11.035, PII S0006899305016239
    • Gong JP, Onaivi ES, Ishiguro H, Liu QR, Tagliaferro PA, Brusco A et al (2006). Cannabinoid CB2 receptors: immunohistochemical localization in rat brain. Brain Res 1071: 10-23. (Pubitemid 43255471)
    • (2006) Brain Research , vol.1071 , Issue.1 , pp. 10-23
    • Gong, J.-P.1    Onaivi, E.S.2    Ishiguro, H.3    Liu, Q.-R.4    Tagliaferro, P.A.5    Brusco, A.6    Uhl, G.R.7
  • 34
    • 61949104116 scopus 로고    scopus 로고
    • Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: Association with N-methyl-D-aspartic acid receptor up-regulation
    • Gray L, Van den Buuse M, Scarr E, Dean B, Hannan AJ (2009). Clozapine reverses schizophrenia-related behaviours in the metabotropic glutamate receptor 5 knockout mouse: association with N-methyl-D-aspartic acid receptor up-regulation. Int J Neuropsychopharmacol 12: 45-60.
    • (2009) Int J Neuropsychopharmacol , vol.12 , pp. 45-60
    • Gray, L.1    Van Den Buuse, M.2    Scarr, E.3    Dean, B.4    Hannan, A.J.5
  • 36
    • 67650439269 scopus 로고    scopus 로고
    • Phenotypic characterization of mice heterozygous for a null mutation of glutamate carboxypeptidase II
    • Han L, Picker JD, Schaevitz LR, Tsai G, Feng J, Jiang Z et al (2009). Phenotypic characterization of mice heterozygous for a null mutation of glutamate carboxypeptidase II. Synapse 63: 625-635.
    • (2009) Synapse , vol.63 , pp. 625-635
    • Han, L.1    Picker, J.D.2    Schaevitz, L.R.3    Tsai, G.4    Feng, J.5    Jiang, Z.6
  • 38
    • 46049086735 scopus 로고    scopus 로고
    • Behavioral abnormalities and dopamine reductions in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia
    • Hattori S, Murotani T, Matsuzaki S, Ishizuka T, Kumamoto N, Takeda M et al (2008). Behavioral abnormalities and dopamine reductions in sdy mutant mice with a deletion in Dtnbp1, a susceptibility gene for schizophrenia. Biochem Biophys Res Commun 373: 298-302.
    • (2008) Biochem Biophys Res Commun , vol.373 , pp. 298-302
    • Hattori, S.1    Murotani, T.2    Matsuzaki, S.3    Ishizuka, T.4    Kumamoto, N.5    Takeda, M.6
  • 39
    • 0025954862 scopus 로고
    • Characterization and localization of cannabi-noid receptors in rat brain: A quantitative in vitro autoradio-graphic study
    • Herkenham M, Lynn AB, Johnson MR, Melvin LS, de Costa BR, Rice KC (1991). Characterization and localization of cannabi-noid receptors in rat brain: a quantitative in vitro autoradio-graphic study. J Neurosci 11: 563-583.
    • (1991) J Neurosci , vol.11 , pp. 563-583
    • Herkenham, M.1    Lynn, A.B.2    Johnson, M.R.3    Melvin, L.S.4    De Costa, B.R.5    Rice, K.C.6
  • 41
    • 0018991381 scopus 로고
    • Reflex modification in the domain of startle: I. Some empirical findings and their implications for how the nervous system processes sensory input
    • Hoffman HS, Ison JR (1980). Reflex modification in the domain of startle: I. Some empirical findings and their implications for how the nervous system processes sensory input. Psychol Rev 87: 175-189.
    • (1980) Psychol Rev , vol.87 , pp. 175-189
    • Hoffman, H.S.1    Ison, J.R.2
  • 42
    • 43349106822 scopus 로고    scopus 로고
    • Nogo receptor 1 (RTN4R) as a candidate gene for schizophrenia: Analysis using human and mouse genetic approaches
    • Hsu R, Woodroffe A, Lai W-S, Cook MN, Mukai J, Dunning JP et al (2007). Nogo receptor 1 (RTN4R) as a candidate gene for schizophrenia: analysis using human and mouse genetic approaches. PLoS ONE 2: e1234.
    • (2007) PLoS ONE , vol.2
    • Hsu, R.1    Woodroffe, A.2    Lai, W.-S.3    Cook, M.N.4    Mukai, J.5    Dunning, J.P.6
  • 43
    • 33745427099 scopus 로고    scopus 로고
    • 2A and 2C receptor mRNA expression in the rat brain
    • DOI 10.1016/j.bbr.2006.03.040, PII S0166432806002002
    • Huang X-F, Han M, Huang X, Zavitsanou K, Deng C (2006). Olanzapine differentially affects 5-HT2A and 2C receptor mRNA expression in the rat brain. Behav Brain Res 171: 355-362. (Pubitemid 43946500)
    • (2006) Behavioural Brain Research , vol.171 , Issue.2 , pp. 355-362
    • Huang, X.-F.1    Han, M.2    Huang, X.3    Zavitsanou, K.4    Deng, C.5
  • 44
    • 53349156385 scopus 로고    scopus 로고
    • Identification of YWHAE, a gene encoding 14-3-3epsilon, as a possible susceptibility gene for schizophrenia
    • Ikeda M, Hikita T, Taya S, Uraguchi-Asaki J, Toyo-oka K, Wynshaw-Boris A et al (2008). Identification of YWHAE, a gene encoding 14-3-3epsilon, as a possible susceptibility gene for schizophrenia. Hum Mol Genet 17: 3212-3222.
    • (2008) Hum Mol Genet , vol.17 , pp. 3212-3222
    • Ikeda, M.1    Hikita, T.2    Taya, S.3    Uraguchi-Asaki, J.4    Toyo-Oka, K.5    Wynshaw-Boris, A.6
  • 46
  • 47
    • 46749102174 scopus 로고    scopus 로고
    • Signs and symptoms in the pre-psychotic phase: Description and implications for diagnostic trajectories
    • DOI 10.1017/S0033291708003152, PII S0033291708003152
    • Iyer S, Boekestyn L, Cassidy C, King S, Joober R, Malla A (2008). Signs and symptoms in the pre-psychotic phase: description and implications for diagnostic trajectories. Psychol Med 38: 1147-1156. (Pubitemid 351950151)
    • (2008) Psychological Medicine , vol.38 , Issue.8 , pp. 1147-1156
    • Iyer, S.N.1    Boekestyn, L.2    Cassidy, C.M.3    King, S.4    Joober, R.5    Malla, A.K.6
  • 49
    • 34748906661 scopus 로고    scopus 로고
    • Altered motor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: Implications for understanding schizophrenia
    • DOI 10.1111/j.1601-183X.2006.00298.x
    • Karl T, Duffy L, Scimone A, Harvey RP, Schofield PR (2007). Altered motor activity, exploration and anxiety in heterozygous neuregulin 1 mutant mice: implications for understanding schizophrenia. Genes Brain Behav 6: 677-687. (Pubitemid 47476190)
    • (2007) Genes, Brain and Behavior , vol.6 , Issue.7 , pp. 677-687
    • Karl, T.1    Duffy, L.2    Scimone, A.3    Harvey, R.P.4    Schofield, P.R.5
  • 50
    • 51349141952 scopus 로고    scopus 로고
    • Endocannabinoid signaling as a synaptic circuit breaker in neurological disease
    • Katona I, Freund TF (2008). Endocannabinoid signaling as a synaptic circuit breaker in neurological disease. Nat Med 14: 923-930.
    • (2008) Nat Med , vol.14 , pp. 923-930
    • Katona, I.1    Freund, T.F.2
  • 51
    • 77952760363 scopus 로고    scopus 로고
    • Effect of aripiprazole, risperidone, and olanzapine on the acoustic startle response in Japanese chronic schizophrenia
    • Kishi T, Moriwaki M, Kitajima T, Kawashima K, Okochi T, Fukuo Y et al (2010). Effect of aripiprazole, risperidone, and olanzapine on the acoustic startle response in Japanese chronic schizophrenia. Psychopharmacology 209: 185-190.
    • (2010) Psychopharmacology , vol.209 , pp. 185-190
    • Kishi, T.1    Moriwaki, M.2    Kitajima, T.3    Kawashima, K.4    Okochi, T.5    Fukuo, Y.6
  • 54
    • 0023255981 scopus 로고
    • The use of a plus-maze to measure anxiety in the mouse
    • Lister RG (1987). The use of a plus-maze to measure anxiety in the mouse. Psychopharmacology 92: 180-185. (Pubitemid 17072893)
    • (1987) Psychopharmacology , vol.92 , Issue.2 , pp. 180-185
    • Lister, R.G.1
  • 55
    • 0036166628 scopus 로고    scopus 로고
    • Involvement of CB1 cannabinoid receptors in emotional behaviour
    • DOI 10.1007/s00213-001-0946-5
    • Martin M, Ledent C, Parmentier M, Maldonado R, Valverde O (2002). Involvement of CB1 cannabinoid receptors in emotional behaviour. Psychopharmacology 159: 379-387. (Pubitemid 34143362)
    • (2002) Psychopharmacology , vol.159 , Issue.4 , pp. 379-387
    • Martin, M.1    Ledent, C.2    Parmentier, M.3    Maldonado, R.4    Valverde, O.5
  • 56
    • 71649096747 scopus 로고    scopus 로고
    • The relationship between prepulse inhibition and general psychopathology in patients with schizophrenia treated with long-acting risperidone
    • Martinez-Gras I, Rubio G, del Manzano BA, Rodriguez-Jimenez R, Garcia-Sanchez F, Bagney A et al (2009). The relationship between prepulse inhibition and general psychopathology in patients with schizophrenia treated with long-acting risperidone. Schizophr Res 115: 215-221.
    • (2009) Schizophr Res , vol.115 , pp. 215-221
    • Martinez-Gras, I.1    Rubio, G.2    Del Manzano, B.A.3    Rodriguez-Jimenez, R.4    Garcia-Sanchez, F.5    Bagney, A.6
  • 58
    • 50349096587 scopus 로고    scopus 로고
    • In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems
    • Di Giovanni G, Di Matteo V, Esposito E (eds) Elsevier: Amsterdam
    • Meltzer HY, Huang M (2008). In vivo actions of atypical antipsychotic drug on serotonergic and dopaminergic systems. In: Di Giovanni G, Di Matteo V, Esposito E (eds). Progress in Brain Research, Vol 172, Elsevier: Amsterdam. pp 177-197.
    • (2008) Progress in Brain Research , vol.172 , pp. 177-197
    • Meltzer, H.Y.1    Huang, M.2
  • 59
    • 0033588176 scopus 로고    scopus 로고
    • Mice with reduced NMDA receptor expression display behaviors related to schizophrenia
    • DOI 10.1016/S0092-8674(00)81972-8
    • Mohn AR, Gainetdinov RR, Caron MG, Koller BH (1999). Mice with reduced NMDA receptor expression display behaviors related to schizophrenia. Cell 98: 427-436. (Pubitemid 29402481)
    • (1999) Cell , vol.98 , Issue.4 , pp. 427-436
    • Mohn, A.R.1    Gainetdinov, R.R.2    Caron, M.G.3    Koller, B.H.4
  • 60
    • 43749124214 scopus 로고    scopus 로고
    • Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis
    • DOI 10.1192/bjp.bp.107.046649
    • Morgan CJ, Curran HV (2008). Effects of cannabidiol on schizophrenia-like symptoms in people who use cannabis. Br J Psychiatry 192: 306-307. (Pubitemid 351692406)
    • (2008) British Journal of Psychiatry , vol.192 , Issue.4 , pp. 306-307
    • Morgan, C.J.A.1    Curran, H.V.2
  • 61
    • 70349469579 scopus 로고    scopus 로고
    • Prepulse inhibition of the startle response with chronic schizophrenia: A replication study
    • Moriwaki M, Kishi T, Takahashi H, Hashimoto R, Kawashima K, Okochi T et al (2009). Prepulse inhibition of the startle response with chronic schizophrenia: a replication study. Neurosci Res 65: 259-262.
    • (2009) Neurosci Res , vol.65 , pp. 259-262
    • Moriwaki, M.1    Kishi, T.2    Takahashi, H.3    Hashimoto, R.4    Kawashima, K.5    Okochi, T.6
  • 62
    • 0027515373 scopus 로고
    • Molecular characterization of a peripheral receptor for cannabinoids
    • DOI 10.1038/365061a0
    • Munro S, Thomas KL, Abu-Shaar M (1993). Molecular characterization of a peripheral receptor for cannabinoids. Nature 365: 61-65. (Pubitemid 23305569)
    • (1993) Nature , vol.365 , Issue.6441 , pp. 61-65
    • Munro, S.1    Thomas, K.L.2    Abu-Shaar, M.3
  • 64
    • 71749104726 scopus 로고    scopus 로고
    • Cannabinoid receptors in brain: Pharmaco-genetics, neuropharmacology, neurotoxicology, and potential therapeutic applications
    • Hari Shanker S (ed.) Academic Press: New York
    • Onaivi ES (2009). Cannabinoid receptors in brain: pharmaco-genetics, neuropharmacology, neurotoxicology, and potential therapeutic applications. In: Hari Shanker S (ed.). International Review of Neurobiology Vol 88, Academic Press: New York. pp 335-369.
    • (2009) International Review of Neurobiology , vol.88 , pp. 335-369
    • Onaivi, E.S.1
  • 65
    • 53549118886 scopus 로고    scopus 로고
    • Behavioral effects of CB2 cannabinoid receptor activation and its influence on food and alcohol consumption
    • Onaivi ES, Carpio O, Ishiguro H, Schanz N, Uhl GR, Benno R (2008). Behavioral effects of CB2 cannabinoid receptor activation and its influence on food and alcohol consumption. Ann N Y Acad Sci 1139: 426-433.
    • (2008) Ann N y Acad Sci , vol.1139 , pp. 426-433
    • Onaivi, E.S.1    Carpio, O.2    Ishiguro, H.3    Schanz, N.4    Uhl, G.R.5    Benno, R.6
  • 67
    • 33845603466 scopus 로고    scopus 로고
    • Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation
    • Palazuelos J, Aguado T, Egia A, Mechoulam R, Guzman M, Galve-Roperh I (2006). Non-psychoactive CB2 cannabinoid agonists stimulate neural progenitor proliferation. FASEB J 20: 2405-2407.
    • (2006) FASEB J , vol.20 , pp. 2405-2407
    • Palazuelos, J.1    Aguado, T.2    Egia, A.3    Mechoulam, R.4    Guzman, M.5    Galve-Roperh, I.6
  • 68
    • 0021006953 scopus 로고
    • Punch sampling biopsy technique
    • Palkovits M (1983). Punch sampling biopsy technique. Methods Enzymol 103: 368-376.
    • (1983) Methods Enzymol , vol.103 , pp. 368-376
    • Palkovits, M.1
  • 70
    • 77953521020 scopus 로고    scopus 로고
    • Motor behavior abnormalities in drug-näve patients with schizophrenia spectrum disorders
    • Peralta V, Campos MS, Garća de Jalón E, Cuesta MJ (2010). Motor behavior abnormalities in drug-näve patients with schizophrenia spectrum disorders. Mov Disord 25: 1068-1076.
    • (2010) Mov Disord , vol.25 , pp. 1068-1076
    • Peralta, V.1    Campos, M.S.2    Garća De Jalón, E.3    Cuesta, M.J.4
  • 71
    • 57649166962 scopus 로고    scopus 로고
    • Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: Prominent effects of dopamine transporter deletions
    • Perona MT, Waters S, Hall FS, Sora I, Lesch KP, Murphy DL et al (2008). Animal models of depression in dopamine, serotonin, and norepinephrine transporter knockout mice: prominent effects of dopamine transporter deletions. Behav Pharmacol 19: 566-574.
    • (2008) Behav Pharmacol , vol.19 , pp. 566-574
    • Perona, M.T.1    Waters, S.2    Hall, F.S.3    Sora, I.4    Lesch, K.P.5    Murphy, D.L.6
  • 72
    • 70349661979 scopus 로고    scopus 로고
    • A reverse-translational study of dysfunctional exploration in psychiatric disorders: From mice to men
    • Perry W, Minassian A, Paulus MP, Young JW, Kincaid MJ, Ferguson EJ et al (2009). A reverse-translational study of dysfunctional exploration in psychiatric disorders: from mice to men. Arch Gen Psychiatry 66: 1072-1080.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 1072-1080
    • Perry, W.1    Minassian, A.2    Paulus, M.P.3    Young, J.W.4    Kincaid, M.J.5    Ferguson, E.J.6
  • 73
    • 58149335563 scopus 로고    scopus 로고
    • Atypical antipsychotics clozapine and quetiapine attenuate prepulse inhibition deficits in dopamine transporter knockout mice
    • Powell SB, Young JW, Ong JC, Caron MG, Geyer MA (2008). Atypical antipsychotics clozapine and quetiapine attenuate prepulse inhibition deficits in dopamine transporter knockout mice. Behav Pharmacol 19: 562-565.
    • (2008) Behav Pharmacol , vol.19 , pp. 562-565
    • Powell, S.B.1    Young, J.W.2    Ong, J.C.3    Caron, M.G.4    Geyer, M.A.5
  • 74
    • 76649087941 scopus 로고    scopus 로고
    • Serotonin modulates fast-spiking interneuron and synchronous activity in the rat prefrontal cortex through 5-HT1A and 5-HT2A receptors
    • Puig MV, Watakabe A, Ushimaru M, Yamamori T, Kawaguchi Y (2010). Serotonin modulates fast-spiking interneuron and synchronous activity in the rat prefrontal cortex through 5-HT1A and 5-HT2A receptors. J Neurosci 30: 2211-2222.
    • (2010) J Neurosci , vol.30 , pp. 2211-2222
    • Puig, M.V.1    Watakabe, A.2    Ushimaru, M.3    Yamamori, T.4    Kawaguchi, Y.5
  • 75
    • 70350547582 scopus 로고    scopus 로고
    • Further pharmacological characterization of 5-HT2C receptor agonist-induced inhibition of 5-HT neuronal activity in the dorsal raphe nucleus 'in vivo'
    • Quérée P, Peters S, Sharp T (2009). Further pharmacological characterization of 5-HT2C receptor agonist-induced inhibition of 5-HT neuronal activity in the dorsal raphe nucleus 'in vivo'. Br J Pharmacol 158: 1477-1485.
    • (2009) Br J Pharmacol , vol.158 , pp. 1477-1485
    • Quérée, P.1    Peters, S.2    Sharp, T.3
  • 76
    • 58149339634 scopus 로고    scopus 로고
    • Crucial role of CB2 cannabinoid receptor in the regulation of central immune responses during neuropathic pain
    • Racz I, Nadal X, Alferink J, Banos JE, Rehnelt J, Martin M et al (2008). Crucial role of CB2 cannabinoid receptor in the regulation of central immune responses during neuropathic pain. J Neurosci 28: 12125-12135.
    • (2008) J Neurosci , vol.28 , pp. 12125-12135
    • Racz, I.1    Nadal, X.2    Alferink, J.3    Banos, J.E.4    Rehnelt, J.5    Martin, M.6
  • 77
    • 0035143189 scopus 로고    scopus 로고
    • Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: Differential effects of D1 and D2 receptor antagonists
    • Ralph RJ, Paulus MP, Fumagalli F, Caron MG, Geyer MA (2001). Prepulse inhibition deficits and perseverative motor patterns in dopamine transporter knock-out mice: Differential effects of D1 and D2 receptor antagonists. J Neurosci 21: 305-313. (Pubitemid 32098754)
    • (2001) Journal of Neuroscience , vol.21 , Issue.1 , pp. 305-313
    • Ralph, R.J.1    Paulus, M.P.2    Fumagalli, F.3    Caron, M.G.4    Geyer, M.A.5
  • 78
    • 18444385647 scopus 로고    scopus 로고
    • The neurodevelopmental model of schizophrenia: Update 2005
    • DOI 10.1038/sj.mp.4001642
    • Rapoport JL, Addington AM, Frangou S, Psych MR (2005). The neurodevelopmental model of schizophrenia: update 2005. Mol Psychiatry 10: 434-449. (Pubitemid 40646432)
    • (2005) Molecular Psychiatry , vol.10 , Issue.5 , pp. 434-449
    • Rapoport, J.L.1    Addington, A.M.2    Frangou, S.3    Psych, M.R.C.4
  • 80
    • 34547423806 scopus 로고    scopus 로고
    • Adult mice with reduced Nurr1 expression: An animal model for schizophrenia
    • DOI 10.1038/sj.mp.4001993, PII 4001993
    • Rojas P, Joodmardi E, Hong Y, Perlmann T, Ogren SO (2007). Adult mice with reduced Nurr1 expression: an animal model for schizophrenia. Mol Psychiatry 12: 756-766. (Pubitemid 47172691)
    • (2007) Molecular Psychiatry , vol.12 , Issue.8 , pp. 756-766
    • Rojas, P.1    Joodmardi, E.2    Hong, Y.3    Perlmann, T.4    Ogren, S.O.5
  • 81
    • 33749041047 scopus 로고    scopus 로고
    • Neurobiology of Schizophrenia
    • DOI 10.1016/j.neuron.2006.09.015, PII S0896627306007227
    • Ross CA, Margolis RL, Reading SA, Pletnikov M, Coyle JT (2006). Neurobiology of schizophrenia. Neuron 52: 139-153. (Pubitemid 44466356)
    • (2006) Neuron , vol.52 , Issue.1 , pp. 139-153
    • Ross, C.A.1    Margolis, R.L.2    Reading, S.A.J.3    Pletnikov, M.4    Coyle, J.T.5
  • 82
    • 53349143178 scopus 로고    scopus 로고
    • Mice lacking the schizophrenia-associated protein FEZ1 manifest hyperactivity and enhanced responsiveness to psychostimulants
    • Sakae N, Yamasaki N, Kitaichi K, Fukuda T, Yamada M, Yoshikawa H et al (2008). Mice lacking the schizophrenia-associated protein FEZ1 manifest hyperactivity and enhanced responsiveness to psychostimulants. Hum Mol Genet 17: 3191-3203.
    • (2008) Hum Mol Genet , vol.17 , pp. 3191-3203
    • Sakae, N.1    Yamasaki, N.2    Kitaichi, K.3    Fukuda, T.4    Yamada, M.5    Yoshikawa, H.6
  • 83
    • 0032521675 scopus 로고    scopus 로고
    • Adrenergic α(2C)-receptors modulate the acoustic startle reflex, prepulse inhibition, and aggression in mice
    • Sallinen J, Haapalinna A, Viitamaa T, Kobilka BK, Scheinin M (1998). Adrenergic alpha 2C-receptors modulate the acoustic startle reflex, prepulse inhibition, and aggression in mice. J Neurosci 18: 3035-3042. (Pubitemid 28163233)
    • (1998) Journal of Neuroscience , vol.18 , Issue.8 , pp. 3035-3042
    • Sallinen, J.1    Haapalinna, A.2    Viitamaa, T.3    Kobilka, B.K.4    Scheinin, M.5
  • 84
    • 0034668118 scopus 로고    scopus 로고
    • Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: Comparison of endpoint and real-time methods
    • Schmittgen TD, Zakrajsek BA, Mills AG, Gorn V, Singer MJ, Reed MW (2000). Quantitative reverse transcription-polymerase chain reaction to study mRNA decay: comparison of endpoint and real-time methods. Anal Biochem 285: 194-204.
    • (2000) Anal Biochem , vol.285 , pp. 194-204
    • Schmittgen, T.D.1    Zakrajsek, B.A.2    Mills, A.G.3    Gorn, V.4    Singer, M.J.5    Reed, M.W.6
  • 85
    • 0029608707 scopus 로고
    • In vitro receptor binding and in vivo receptor occupancy in rat and guinea pig brain: Risperidone compared with antipsychotics hitherto used
    • Schotte A, Bonaventure P, Janssen PFM, Leysen JE (1995). In vitro receptor binding and in vivo receptor occupancy in rat and guinea pig brain: Risperidone compared with antipsychotics hitherto used. Jpn J Pharmacol 69: 399-412. (Pubitemid 26013775)
    • (1995) Japanese Journal of Pharmacology , vol.69 , Issue.4 , pp. 399-412
    • Schotte, A.1    Bonaventure, P.2    Janssen, P.F.M.3    Leysen, J.E.4
  • 87
    • 0026036186 scopus 로고
    • Effects of spiperone, raclopride, SCH 23390 and clozapine on apomor- phine inhibition of sensorimotor gating of the startle response in the rat
    • Swerdlow NR, Keith VA, Braff DL, Geyer MA (1991). Effects of spiperone, raclopride, SCH 23390 and clozapine on apomor- phine inhibition of sensorimotor gating of the startle response in the rat. J Pharmacol Exp Ther 256: 530-536.
    • (1991) J Pharmacol Exp Ther , vol.256 , pp. 530-536
    • Swerdlow, N.R.1    Keith, V.A.2    Braff, D.L.3    Geyer, M.A.4
  • 89
    • 68249162360 scopus 로고    scopus 로고
    • Abnormal social behavior, hyperactivity, impaired remote spatial memory, and increased D1-mediated dopaminer-gic signaling in neuronal nitric oxide synthase knockout mice
    • Tanda K, Nishi A, Matsuo N, Nakanishi K, Yamasaki N, Sugimoto T et al (2009). Abnormal social behavior, hyperactivity, impaired remote spatial memory, and increased D1-mediated dopaminer-gic signaling in neuronal nitric oxide synthase knockout mice. Mol Brain 2: 19.
    • (2009) Mol Brain , vol.2 , pp. 19
    • Tanda, K.1    Nishi, A.2    Matsuo, N.3    Nakanishi, K.4    Yamasaki, N.5    Sugimoto, T.6
  • 90
    • 77649234848 scopus 로고    scopus 로고
    • Modulation of prepulse inhibition through both M1 and M4 muscarinic receptors in mice
    • Thomsen M, Wess J, Fulton B, Fink-Jensen A, Caine S (2010). Modulation of prepulse inhibition through both M1 and M4 muscarinic receptors in mice. Psychopharmacology 208: 401-416.
    • (2010) Psychopharmacology , vol.208 , pp. 401-416
    • Thomsen, M.1    Wess, J.2    Fulton, B.3    Fink-Jensen, A.4    Caine, S.5
  • 91
    • 69549105668 scopus 로고    scopus 로고
    • Immunodensity and mRNA expression of A2A adenosine, D2 dopamine, and CB1 cannabinoid receptors in postmortem frontal cortex of subjects with schizophrenia: Effect of antipsychotic treatment
    • Urigüen L, Garća-Fuster M, Callado L, Morentin B, La Harpe R, Casadó V et al (2009). Immunodensity and mRNA expression of A2A adenosine, D2 dopamine, and CB1 cannabinoid receptors in postmortem frontal cortex of subjects with schizophrenia: effect of antipsychotic treatment. Psychopharmacology 206: 313-324.
    • (2009) Psychopharmacology , vol.206 , pp. 313-324
    • Urigüen, L.1    Garća-Fuster, M.2    Callado, L.3    Morentin, B.4    La Harpe, R.5    Casadó, V.6
  • 92
    • 1842664350 scopus 로고    scopus 로고
    • 1 receptors
    • DOI 10.1016/j.neuropharm.2004.01.003, PII S0028390804000139
    • Urigüen L, Pérez-Rial S, Ledent C, Palomo T, Manzanares J (2004). Impaired action of anxiolytic drugs in mice deficient in cannabinoid CB1 receptors. Neuropharmacology 46: 966-973. (Pubitemid 38471950)
    • (2004) Neuropharmacology , vol.46 , Issue.7 , pp. 966-973
    • Uriguen, L.1    Perez-Rial, S.2    Ledent, C.3    Palomo, T.4    Manzanares, J.5
  • 94
    • 0031452134 scopus 로고    scopus 로고
    • Individual differences in response to imipramine in the mouse tail suspension test
    • DOI 10.1007/s002130050475
    • Vaugeois JM, Passera G, Zuccaro F, Costentin J (1997). Individual differences in response to imipramine in the mouse tail suspension test. Psychopharmacology 134: 387-391. (Pubitemid 28023413)
    • (1997) Psychopharmacology , vol.134 , Issue.4 , pp. 387-391
    • Vaugeois, J.-M.1    Passera, G.2    Zuccaro, F.3    Costentin, J.4
  • 96
    • 74949107496 scopus 로고    scopus 로고
    • Constitutive genetic deletion of the growth regulator Nogo-A induces schizophrenia-related endophenotypes
    • Willi R, Weinmann O, Winter C, Klein J, Sohr R, Schnell L et al (2010). Constitutive genetic deletion of the growth regulator Nogo-A induces schizophrenia-related endophenotypes. J Neurosci 30: 556-567.
    • (2010) J Neurosci , vol.30 , pp. 556-567
    • Willi, R.1    Weinmann, O.2    Winter, C.3    Klein, J.4    Sohr, R.5    Schnell, L.6
  • 98
    • 34548160376 scopus 로고    scopus 로고
    • Effects of olanzapine, risperidone and haloperidol on prepulse inhibition in schizophrenia patients: A double-blind, randomized controlled trial
    • DOI 10.1016/j.schres.2007.05.039, PII S0920996407002526
    • Wynn JK, Green MF, Sprock J, Light GA, Widmark C, Reist C et al (2007). Effects of olanzapine, risperidone and haloperidol on prepulse inhibition in schizophrenia patients: a double-blind, randomized controlled trial. Schizophr Res 95: 134-142. (Pubitemid 47313638)
    • (2007) Schizophrenia Research , vol.95 , Issue.1-3 , pp. 134-142
    • Wynn, J.K.1    Green, M.F.2    Sprock, J.3    Light, G.A.4    Widmark, C.5    Reist, C.6    Erhart, S.7    Marder, S.R.8    Mintz, J.9    Braff, D.L.10
  • 99
    • 64949175022 scopus 로고    scopus 로고
    • Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders
    • Yamasaki N, Maekawa M, Kobayashi K, Kajii Y, Maeda J, Soma M et al (2008). Alpha-CaMKII deficiency causes immature dentate gyrus, a novel candidate endophenotype of psychiatric disorders. Mol Brain 1: 6.
    • (2008) Mol Brain , vol.1 , pp. 6
    • Yamasaki, N.1    Maekawa, M.2    Kobayashi, K.3    Kajii, Y.4    Maeda, J.5    Soma, M.6
  • 100
    • 33748808963 scopus 로고    scopus 로고
    • Norepinephrine transporter blockade can normalize the prepulse inhibition deficits found in dopamine transporter knockout mice
    • DOI 10.1038/sj.npp.1301009, PII 1301009
    • Yamashita M, Fukushima S, Shen H-w, Hall FS, Uhl GR, Numachi Y et al (2006). Norepinephrine transporter blockade can normalize the prepulse inhibition deficits found in dopamine transporter knockout mice. Neuropsychopharmacology 31: 2132-2139. (Pubitemid 44413190)
    • (2006) Neuropsychopharmacology , vol.31 , Issue.10 , pp. 2132-2139
    • Yamashita, M.1    Fukushima, S.2    Shen, H.-W.3    Hall, F.S.4    Uhl, G.R.5    Numachi, Y.6    Kobayashi, H.7    Sora, I.8
  • 102
    • 0037164374 scopus 로고    scopus 로고
    • Self reported cannabis use as a risk factor for schizophrenia in Swedish conscripts of 1969: Historical cohort study
    • Zammit S, Allebeck P, Andreasson S, Lundberg I, Lewis G (2002). Self reported cannabis use as a risk factor for schizophrenia in Swedish conscripts of 1969: historical cohort study. BMJ 325: 1199.
    • (2002) BMJ , vol.325 , pp. 1199
    • Zammit, S.1    Allebeck, P.2    Andreasson, S.3    Lundberg, I.4    Lewis, G.5


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