Neuroimaging abnormalities in the subgenual prefrontal cortex: Implications for the pathophysiology of familial mood disorders

Molecular Psychiatry

Volumn 3, Issue 3, 1998, Pages 220-226

  Drevets, W C ^a,c   Ongur D ^b   Price, J L ^b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c PRESBYTERIAN UNIVERSITY HOSPITAL   (United States)

Author keywords

Anterior cingulate; Bipolar disorder; Emotion; Glia; Major depression; MRI; PET

Indexed keywords

AFFECTIVE NEUROSIS; ANIMAL EXPERIMENT; ARTICLE; AUTOPSY; BRAIN DEPTH STIMULATION; CONTROLLED STUDY; CORPUS CALLOSUM; DEPRESSION; FAMILIAL DISEASE; GLIA; GRAY MATTER; HUMAN; HUMAN TISSUE; MANIC DEPRESSIVE PSYCHOSIS; MOOD; NEUROENDOCRINOLOGY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PREFRONTAL CORTEX; PRIORITY JOURNAL; STRESS;

EID: 0031782081     PISSN: 13594184     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.mp.4000370     Document Type: Article

References (57)

1. Drevets WC, Price JL, Simpson JR, Todd RD, Reich T, Vannier M et al. Subgenual prefrontal cortex abnormalities in mood disorders. Nature 1997; 386: 824-827.
2. Drevets WC, Videen TO, Price JL, Preskorn SH, Carmichael ST, Raichle ME. A functional anatomical study of unipolar depression. J Neurosci 1992; 12: 3628-3641.
3. Fox PT, Perlmutter JS, Raichle ME. A stereotactic method of anatomical localization for positron emission tomography. J Comput Assist Tomogr 1385; 9: 141-153.
4. Talairach J, Tournoux P. Co-Planar Stereotaxic Atlas of the Human Brain. Thieme: Stuttgart, 1988, pp 1-122.
5. Mazziotta JC, Phelps ME, Plummer D, Kuhl DE. Quantitation in positron emission computed tomography: 5. Physical-anatomical effects. J Comput Assist Tomogr 1981; 5: 734-743.
6. Carmichael ST, Price JL. Architectonic subdivision of the orbital and medial prefrontal cortex in the macaque monkey. J Comp Neurol 1994; 346: 366-402.
7. Drevets WC, Todd RD. Depression, mania and related disorders. In: Guze SB (ed). Adult Psychiatry. Mosby: St Louis, MO, 1997, pp 99-142.
8. Winokur G. The development and validity of familial subtypes in primary unipolar depression. Pharmacopsychiatry 1982; 15: 142-146.
9. Drevets WC, Spitznagel E, Raichle ME. Functional anatomical differences between major depressive subtypes. J Cereb Blood Flow Metab 1995; 15: S93.
10. Drevets WC, Botteron K. Neuroimaging in psychiatry. In: Guze SB (ed). Adult Psychiatry. Mosby: St Louis, MO, 1997, pp 53-82.
11. Pearlson GD, Barta PE, Powers RE, Menon RR, Richards SS, Aylward EH et al. Medial and superior temporal gyral volumes and cerebral asymmetry in schizophrenia versus bipolar disorder. Biol Psychiatry 1997; 41: 1-14.
12. Carmichael ST, Price JL. Limbic connections of the orbital and medial prefrontal cortex in macaque monkeys. J Comp Neurol 1995; 363: 615-641.
13. Krishnan KRR, McDonald WM, Escalona PR et al. Magnetic resonance imaging of the caudate nuclei in depression: preliminary observations. Arch Gen Psychiatry 1992; 49: 553-557.
14. Magistretti PJ, Pellerin L, Martin JL. Brain energy metabolism: an integrated cellular perspective. In: Bloom FE, Kupfer DJ (eds). Psychopharmacology: The Fourth Generation of Progress. Raven Press: New York, 1995, pp 921-932.
15. Drevets WC. Functional neuromaging studies of depression: the anatomy of melancholia. Ann Rev Medicine 1998; 49: 331-361.
16. Buchsbaum MS, Wu J, Siegel BV, Hackett E, Trenary KM, Abel L et al. Effect of sertraline on regional metabolic rate in patients with affective disorder. Biol Psychiatry 1997; 41: 15-22.
17. Mayberg HS, Liotti M, Brannan SK, McGinnis S, Jerabek PA, Martin CC et al. Disease-specific effects of mood challenge in remitted depression. Neurosci Abs 1997; 23: 1406.
18. George MS, Ketter TA, Parekh PI, Horwitz B, Herscovitch P, Post RM. Brain activity during transient sadness and happiness in healthy women. Am J Psychiatry 1995; 152: 341-351.
19. Neafsey EJ, Terrebeny RR, Hurley KM, Ruit KG, Frysztak RJ. Anterior cingulate cortex in rodents: connections, visceral control functions, and implications for emotion. In: Vogt BA, Gabriel M (eds). Neurobiology of Cingulate Cortex and Limbic Thalamus. Birkhauser: Boston, 1993, pp 206-223.
20. Sesack SR, Deutch AY, Roth RH, Bunney BS. Topographic organization of the efferent projections of the medial prefrontal cortex in the rat: an anterograde tract-tracing study using Phaseolus vulgaris leucoagglutinin. J Comp Neurol 1989; 290: 213-242.
21. Sesack SR, Pickel VM. Prefrontal cortical efferents in the rat synapse on unlabeled neuronal targets of catecholamine terminals in the nucleus accumbens septi and on dopamine neurons in the ventral tegmental area. J Comp Neurol 1392; 320; 145-160.
22. Neafsey EJ, Hurley-Gius KM, Arvanitis D. The topographical organization of neurons in the rat medial frontal, insular and olfactory cortex projecting to the solitary nucleus, olfactory bulb, periaqueductal gray and superior colliculus. Brain Res 1986; 377: 261-270.
23. Damasio AR, Tranel D, Damasio H. Individuals with sociopathic behavior caused by frontal damage fail to respond autonomically to social stimuli. Behav Brain Res 1990; 41: 81-94.
24. Bechara A, Tranel D, Damasio H, Damasio AR. Failure to respond autonomically to anticipated future outcomes following damage to the prefrontal cortex. Cereb Cortex 1996; 6: 215-225.
25. Damasio AR. Descarte's Error: Emotion, Reason, and the Human Brain. Groset/Putnam: New York, 1994; Picador MacMillan: London, 1995.
26. Elliott R, Sahakian BJ, Herrod JJ, Robbins TW, Paykel ES. Abnormal response to negative feedback in unipolar depression: evidence for a diagnosis specific impairment. J Neurol Neurosurg Psychiatry 1997; 63: 74-82.
27. Damasio AR. Towards a neuropathology of emotion and mood. Nature 1997; 386: 769-770.
28. Dioro D, Viau V, Meaney MJ. The role of the medial prefrontal cortex (cingulate gyrus) in the regulation of hypothalamic-pituitary-adrenal responses to stress. J Neurosci 1993; 13: 3839-3847.
29. Young EA, Kotun J, Haskett RF, Grunhaus L, Greden JF, Watson SJ et al. Dissociation between pituitary and adrenal suppression to dexamethasone in depression. Arch Gen Psychiatry 1993; 50: 395-403.
30. Young EA, Haskett RF, Grunhaus L, Pande A, Weinberg VM, Watson SJ et al. Increased evening activation of the hypothalamic-pituitary-adrenal axis in depressed patients. Arch Gen Psychiatry 1994; 51: 701-707.
31. Morgan MA, LeDoux JE. Differential contribution of dorsal and ventral medial prefrontal cortex to the acquisition and extinction of conditioned fear in rats. Behav Neurosci 1995; 109: 681-688.
32. Frysztak RJ, Neafsey EJ. The effect of medial frontal cortex lesions on cardiovascular conditioned emotional responses in the rat. Brain Res 1994; 643: 181-193.
33. Sullivan RM, Gratton A. Lateralization of medial prefrontal cortical modulation of autonomic and neuroendocrine stress responses in rats. Soc Neurosci Abstr 1997; 23: 1085.
34. Henke PW. The telencephalic limbic system and gastric pathology. Neurosci Biobehav Rev 1982; 6: 381-390.
35. Veith RC, Lewis N, Linares OA, Barnes RF, Raskind MA, Villacres EC et al. Sympathetic: nervous system activity in major depression. Arch Gen Psychiatry 1994; 51: 411-422.
36. Pagani M, Lombardi F, Guzzetti S, Rimoldi O, Furlan R, Pizzinelli P et al. Power spectral analysis of heart rate and arterial pressure variabilities as a marker for sympathovagal interaction in man and conscious dog. Circ Res 1986; 59: 178-193.
37. Eckberg DW. Parasympathetic cardiovascular control in human disease: a critical review of methods and results. Am J Physiology 1980; 239: H581-H593.
38. Carney RM, Rich MW, teVelde A, Saini J, Clark K, Freedland KE. The relationship between heart rate, heart rate variability and depression in patients with coronary artery disease. J Psychosom Res 1988; 32: 159-164.
39. Carney RM, Rich MW, Freedland KE, Saini J, teVelde A, Simeone C et al. Major depressive disorder predicts cardiac events in patients with coronary artery disease. Psychosom Med 1988; 50: 627-633.
40. Carney RM, Freedland KE, Rich MW, Smith LJ, Jaffe AS. Ventricular tachycardia and psychiatric depression in patients with coronary artery disease. Am J Med 1993; 95: 23-28.
41. Frasure-Smith N, Lespérance F, Talajic M. Depression and 18-month prognosis after myocardial infarction. Circulation 1995; 91: 999-1005.
42. Leichnetz CR, Astruc J. The efferent projections of the medial prefrontal cortex in the squirrel monkey (saimiri sciureus). Brain Res 1976; 109: 455-472.
43. Crino PB, Morrison JH, Hof PR. Monoaminergic innervation of cingulate cortex. In: Vogt BA, Gabriel M (eds). Neurobiology of Cingulate Cortex and Limbic Thalamus. Birkhauser: Boston, 1993, pp 285-312.
44. Chergui K, Nomikos GG, Mathe JM, Gonon F, Svensson TH. Tonic activation of NMDA receptors causes spontaneous burst discharge of rat midbrain dopamine neurons in vivo. Eur J Neurosci 1993; 5: 137-144.
45. Murase S, Grenhoff J, Chouvet G, Gonon F, Svensson TH. Prefrontal cortex regulates burst firing and transmitter release in rat mesolimbic dopamine neurons. Neurosci Lett 1993; 157: 53-56.
46. Roth RH, Elsworth JD. Biochemical pharmacology of midbrain dopamine neurons. In: Bloom FE, Kupfer DJ (eds). Psychopharmacology: The Fourth Generation of Progress. Raven Press: New York, 1995, pp 227-243.
47. Gariano RF, Groves PM. Electrical stimulation of medial prefrontal and cingulate cortex elicits bursting in a small population of mesencephalic dopamine neurons. In: Kalivas PW, Nemeroff CB (eds). Mesocorticolimbic Dopamine System. Academic Science Press: New York, 1988, pp 505-507.
48. Taber MT, Fibiger HC. Electrical stimulation of the medial prefrontal cortex increases dopamine release in the striatum. Neuropsychopharmacology 1993; 9: 271-275.
49. Schultz W. Dopamine neurons and their role in reward mechanisms. Curr Opin Neurobiol 1997; 7: 131-197.
50. Willner P. Dopaminergic mechanisms in depression and mania. In: Bloom FE, Kupfer DJ (eds). Psychopharmacology: The Fourth Generation of Progress. Raven Press: New York, 1995, pp 921-932.
51. Fibiger HC. The dopamine hypotheses of schizophrenia and mood disorders. In: Willner P, Scheel-Kruger J (eds). The Mesolimbic Dopamine System: From Motivation to Action. Wiley: New York, 1991, pp 615-638.
52. Bunney WE, Brodie HH, Murphy DL, Goodwill FK. Studies of α-methyl-para-tyrosine L-DOPA, and L-tryptophan in depression and mania. Am J Psychiatry 1971; 7: 872-881.
53. Tanda G, Carboni E, Frau R, DiChiara G. Increase of extracellular dopamine in the prefrontal cortex: a trait of drugs with antidepressant potential? Psychopharmacology 1994; 115: 285-288.
54. Nowak G, Trullas R, Layer RT, Skolnick P, Paul IA. Adaptive changes in the N-methyl-D-aspartate receptor complex after chronic treatment with imipramine and 1-aminocyclopropanecarboxylic acid. J Pharmacol Exp Ther 1993; 265: 1380-1386.
55. Paul IA, Nowak G, Layer RT, Popik P, Skolnick P. Adaptation of the N-methyl-D-aspartate receptor complex following chronic antidepressant treatments. J Pharmacol Exp Ther 1994; 269: 95-102.
56. Sporn J, Sachs G. The anticonvulsant lamotrigine in treatment-resistant manic-depressive illness. J Clin Psychopharmacol 1997; 17: 185-189.
57. Nowak G, Ordway GA, Paul IA. Alterations in the N-methyl-D-aspartate (NMDA) receptor complex in the frontal cortex of suicide victims. Brain Res 1995; 675: 157-164.