Suppression of amygdalar endocannabinoid signaling by stress contributes to activation of the hypothalamic-pituitary-adrenal axis

Neuropsychopharmacology

Volumn 34, Issue 13, 2009, Pages 2733-2745

  Hill, Matthew N ^a   McLaughlin, Ryan J ^a   Morrish, Anna C ^a   Viau, Victor ^a   Floresco, Stan B ^a,b   Hillard, Cecilia J ^c   Gorzalka, Boris B ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

Amygdala; Anxiety; Cannabinoid; Corticosterone; HPA axis; Stress

Indexed keywords

1 (2,4 DICHLOROPHENYL) 5 (4 IODOPHENYL) 4 METHYL N (1 PIPERIDYL) 1H PYRAZOLE 3 CARBOXAMIDE; ANANDAMIDE; CANNABINOID 1 RECEPTOR; CORTICOSTERONE; FATTY ACID AMIDASE;

AMYGDALOID NUCLEUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CORTICOSTERONE BLOOD LEVEL; CORTICOSTERONE RELEASE; ENZYME ACTIVITY; ENZYME INHIBITION; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; IMMOBILIZATION STRESS; MALE; MENTAL STRESS; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION;

AMIDOHYDROLASES; AMYGDALA; ANIMALS; ARACHIDONIC ACIDS; BENZAMIDES; CARBAMATES; CORTICOSTERONE; DRUG INTERACTIONS; ENDOCANNABINOIDS; HYPOTHALAMO-HYPOPHYSEAL SYSTEM; MALE; MICROINJECTIONS; PIPERIDINES; PITUITARY-ADRENAL SYSTEM; POLYUNSATURATED ALKAMIDES; PYRAZOLES; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, CANNABINOID, CB1; RESTRAINT, PHYSICAL; SIGNAL TRANSDUCTION; STRESS, PSYCHOLOGICAL; TETRAHYDROCANNABINOL;

EID: 70449529389     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/npp.2009.114     Document Type: Article

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