A broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice

PLoS ONE

Volumn 8, Issue 11, 2013, Pages

  Hölter, Sabine M ^a   Stromberg, Mary ^b   Kovalenko, Marina ^b   Garrett, Lillian ^a   Glasl, Lisa ^a   Lopez, Edith ^b   Guide, Jolene ^b   Götz, Alexander ^a   Hans, Wolfgang ^a   Becker, Lore ^a   Rathkolb, Birgit ^a   Rozman, Jan ^a   Schrewed, Anja ^c   Klingenspor, Martin ^d   Klopstock, Thomas ^e   Schulz, Holger ^a   Wolf, Eckhard ^f   Wursta, Wolfgang ^g,h   Gillis, Tammy ^b   Wakimoto, Hiroko ⁱ   Seidman, Jonathan ⁱ   MacDonald, Marcy E ^b   Cotman, Susan ^b   Gailus Durner, Valérie ^a   Fuchs, Helmut ^a   De Angelis, Martin Hrabě ^a   Lee, Jong Min ^b   Wheeler, Vanessa C ^b   more..

^a INSTITUTE OF EPIDEMIOLOGY   (Germany)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^f UNIVERSITY OF MUNICH   (Germany)

^g MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

^h GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

ⁱ HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; HDH PROTEIN, MOUSE; NERVE PROTEIN; NUCLEAR PROTEIN;

ALLELE; ANIMAL; ANIMAL BEHAVIOR; ANXIETY; AUTONOMIC NERVOUS SYSTEM; C57BL MOUSE; CARDIOVASCULAR DISEASE; GENE TARGETING; GENETICS; HUNTINGTON CHOREA; LEARNING; LUNG; MALE; METABOLISM; MOTOR ACTIVITY; MOUSE MUTANT; MUTATION; ODOR; PATHOLOGY; PATHOPHYSIOLOGY; PHENOTYPE; ROTAROD TEST; SOCIAL BEHAVIOR; TRINUCLEOTIDE REPEAT;

ALLELES; ANIMALS; ANXIETY; AUTONOMIC NERVOUS SYSTEM; BEHAVIOR, ANIMAL; CARDIOVASCULAR DISEASES; GENE KNOCK-IN TECHNIQUES; GLUCOSE; HUNTINGTON DISEASE; LEARNING; LUNG; MALE; MICE, INBRED C57BL; MICE, NEUROLOGIC MUTANTS; MOTOR ACTIVITY; MUTATION; NERVE TISSUE PROTEINS; NUCLEAR PROTEINS; PHENOTYPE; ROTAROD PERFORMANCE TEST; SMELL; SOCIAL BEHAVIOR; TRINUCLEOTIDE REPEAT EXPANSION;

EID: 84894379134     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0080923     Document Type: Article

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