-
1
-
-
0031950826
-
Frontal lobe volume in patients with Huntington's disease
-
Aylward E.H., Anderson N.B., Bylsma F.W., Wagster M.V., Barta P.E., Sherr M., Feeney J., Davis A., Rosenblatt A., Pearlson G.D., Ross C.A. Frontal lobe volume in patients with Huntington's disease. Neurology 1998, 50:252-258.
-
(1998)
Neurology
, vol.50
, pp. 252-258
-
-
Aylward, E.H.1
Anderson, N.B.2
Bylsma, F.W.3
Wagster, M.V.4
Barta, P.E.5
Sherr, M.6
Feeney, J.7
Davis, A.8
Rosenblatt, A.9
Pearlson, G.D.10
Ross, C.A.11
-
2
-
-
33646038884
-
Selective extra-dimensional set shifting deficit in a knock-in mouse model of Huntington's disease
-
Brooks S.P., Betteridge H., Trueman R.C., Jones L., Dunnett S.B. Selective extra-dimensional set shifting deficit in a knock-in mouse model of Huntington's disease. Brain Res. Bull. 2006, 69:452-457.
-
(2006)
Brain Res. Bull.
, vol.69
, pp. 452-457
-
-
Brooks, S.P.1
Betteridge, H.2
Trueman, R.C.3
Jones, L.4
Dunnett, S.B.5
-
3
-
-
36549036813
-
Psychiatric symptoms in Huntington's disease before diagnosis: the predict-HD study
-
Duff K., Paulsen J.S., Beglinger L.J., Langbehn D.R., Stout J.C. Psychiatric symptoms in Huntington's disease before diagnosis: the predict-HD study. Biol. Psychiatry 2007, 62:1341-1346.
-
(2007)
Biol. Psychiatry
, vol.62
, pp. 1341-1346
-
-
Duff, K.1
Paulsen, J.S.2
Beglinger, L.J.3
Langbehn, D.R.4
Stout, J.C.5
-
4
-
-
46749157501
-
Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice
-
Gray M., Shirasaki D.I., Cepeda C., Andre V.M., Wilburn B., Lu X.H., Tao J., Yamazaki I., Li S.H., Sun Y.E., Li X.J., Levine M.S., Yang X.W. Full-length human mutant huntingtin with a stable polyglutamine repeat can elicit progressive and selective neuropathogenesis in BACHD mice. J. Neurosci. 2008, 28:6182-6195.
-
(2008)
J. Neurosci.
, vol.28
, pp. 6182-6195
-
-
Gray, M.1
Shirasaki, D.I.2
Cepeda, C.3
Andre, V.M.4
Wilburn, B.5
Lu, X.H.6
Tao, J.7
Yamazaki, I.8
Li, S.H.9
Sun, Y.E.10
Li, X.J.11
Levine, M.S.12
Yang, X.W.13
-
5
-
-
63849154126
-
In vivo evidence for NMDA receptor-mediated excitotoxicity in a murine genetic model of Huntington disease
-
Heng M.Y., Detloff P.J., Wang P.L., Tsien J.Z., Albin R.L. In vivo evidence for NMDA receptor-mediated excitotoxicity in a murine genetic model of Huntington disease. J. Neurosci. 2009, 29:3200-3205.
-
(2009)
J. Neurosci.
, vol.29
, pp. 3200-3205
-
-
Heng, M.Y.1
Detloff, P.J.2
Wang, P.L.3
Tsien, J.Z.4
Albin, R.L.5
-
6
-
-
34548161707
-
Longitudinal evaluation of the Hdh(CAG)150 knock-in murine model of Huntington's disease
-
Heng M.Y., Tallaksen-Greene S.J., Detloff P.J., Albin R.L. Longitudinal evaluation of the Hdh(CAG)150 knock-in murine model of Huntington's disease. J. Neurosci. 2007, 27:8989-8998.
-
(2007)
J. Neurosci.
, vol.27
, pp. 8989-8998
-
-
Heng, M.Y.1
Tallaksen-Greene, S.J.2
Detloff, P.J.3
Albin, R.L.4
-
7
-
-
0036152343
-
Environmental enrichment slows disease progression in R6/2 Huntington's disease mice
-
Hockly E., Cordery P.M., Woodman B., Mahal A., van Dellen A., Blakemore C., Lewis C.M., Hannan A.J., Bates G.P. Environmental enrichment slows disease progression in R6/2 Huntington's disease mice. Ann. Neurol. 2002, 51:235-242.
-
(2002)
Ann. Neurol.
, vol.51
, pp. 235-242
-
-
Hockly, E.1
Cordery, P.M.2
Woodman, B.3
Mahal, A.4
van Dellen, A.5
Blakemore, C.6
Lewis, C.M.7
Hannan, A.J.8
Bates, G.P.9
-
8
-
-
34447620858
-
Beyond disgust: impaired recognition of negative emotions prior to diagnosis in Huntington's disease
-
Johnson S.A., Stout J.C., Solomon A.C., Langbehn D.R., Aylward E.H., Cruce C.B., Ross C.A., Nance M., Kayson E., Julian-Baros E., Hayden M.R., Kieburtz K., Guttman M., Oakes D., Shoulson I., Beglinger L., Duff K., Penziner E., Paulsen J.S. Beyond disgust: impaired recognition of negative emotions prior to diagnosis in Huntington's disease. Brain 2007, 130:1732-1744.
-
(2007)
Brain
, vol.130
, pp. 1732-1744
-
-
Johnson, S.A.1
Stout, J.C.2
Solomon, A.C.3
Langbehn, D.R.4
Aylward, E.H.5
Cruce, C.B.6
Ross, C.A.7
Nance, M.8
Kayson, E.9
Julian-Baros, E.10
Hayden, M.R.11
Kieburtz, K.12
Guttman, M.13
Oakes, D.14
Shoulson, I.15
Beglinger, L.16
Duff, K.17
Penziner, E.18
Paulsen, J.S.19
-
9
-
-
34547839797
-
Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage
-
Kuhn A., Goldstein D.R., Hodges A., Strand A.D., Sengstag T., Kooperberg C., Becanovic K., Pouladi M.A., Sathasivam K., Cha J.H., Hannan A.J., Hayden M.R., Leavitt B.R., Dunnett S.B., Ferrante R.J., Albin R., Shelbourne P., Delorenzi M., Augood S.J., Faull R.L., Olson J.M., Bates G.P., Jones L., Luthi-Carter R. Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage. Hum. Mol. Genet. 2007, 16:1845-1861.
-
(2007)
Hum. Mol. Genet.
, vol.16
, pp. 1845-1861
-
-
Kuhn, A.1
Goldstein, D.R.2
Hodges, A.3
Strand, A.D.4
Sengstag, T.5
Kooperberg, C.6
Becanovic, K.7
Pouladi, M.A.8
Sathasivam, K.9
Cha, J.H.10
Hannan, A.J.11
Hayden, M.R.12
Leavitt, B.R.13
Dunnett, S.B.14
Ferrante, R.J.15
Albin, R.16
Shelbourne, P.17
Delorenzi, M.18
Augood, S.J.19
Faull, R.L.20
Olson, J.M.21
Bates, G.P.22
Jones, L.23
Luthi-Carter, R.24
more..
-
10
-
-
0035862896
-
Neurological abnormalities in a knock-in mouse model of Huntington's disease
-
Lin C.H., Tallaksen-Greene S., Chien W.M., Cearley J.A., Jackson W.S., Crouse A.B., Ren S., Li X.J., Albin R.L., Detloff P.J. Neurological abnormalities in a knock-in mouse model of Huntington's disease. Hum. Mol. Genet. 2001, 10:137-144.
-
(2001)
Hum. Mol. Genet.
, vol.10
, pp. 137-144
-
-
Lin, C.H.1
Tallaksen-Greene, S.2
Chien, W.M.3
Cearley, J.A.4
Jackson, W.S.5
Crouse, A.B.6
Ren, S.7
Li, X.J.8
Albin, R.L.9
Detloff, P.J.10
-
11
-
-
16044373842
-
Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice
-
Mangiarini L., Sathasivam K., Seller M., Cozens B., Harper A., Hetherington C., Lawton M., Trottier Y., Lehrach H., Davies S.W., Bates G.P. Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice. Cell 1996, 87:493-506.
-
(1996)
Cell
, vol.87
, pp. 493-506
-
-
Mangiarini, L.1
Sathasivam, K.2
Seller, M.3
Cozens, B.4
Harper, A.5
Hetherington, C.6
Lawton, M.7
Trottier, Y.8
Lehrach, H.9
Davies, S.W.10
Bates, G.P.11
-
12
-
-
0037107191
-
Early motor dysfunction and striosomal distribution of huntingtin microaggregates in Huntington's disease knock-in mice
-
Menalled L.B., Sison J.D., Wu Y., Olivieri M., Li X.J., Li H., Zeitlin S., Chesselet M.F. Early motor dysfunction and striosomal distribution of huntingtin microaggregates in Huntington's disease knock-in mice. J. Neurosci. 2002, 22:8266-8276.
-
(2002)
J. Neurosci.
, vol.22
, pp. 8266-8276
-
-
Menalled, L.B.1
Sison, J.D.2
Wu, Y.3
Olivieri, M.4
Li, X.J.5
Li, H.6
Zeitlin, S.7
Chesselet, M.F.8
-
13
-
-
0030564956
-
In vitro autoradiography of ionotropic glutamate receptors in hippocampus and striatum of aged Long-Evans rats: relationship to spatial learning
-
Nicolle M.M., Bizon J.L., Gallagher M. In vitro autoradiography of ionotropic glutamate receptors in hippocampus and striatum of aged Long-Evans rats: relationship to spatial learning. Neuroscience 1996, 74:741-756.
-
(1996)
Neuroscience
, vol.74
, pp. 741-756
-
-
Nicolle, M.M.1
Bizon, J.L.2
Gallagher, M.3
-
14
-
-
33947200596
-
Mitochondrial dysfunction in Huntington's disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice
-
Oliveira J.M., Jekabsons M.B., Chen S., Lin A., Rego A.C., Goncalves J., Ellerby L.M., Nicholls D.G. Mitochondrial dysfunction in Huntington's disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice. J. Neurochem. 2007, 101:241-249.
-
(2007)
J. Neurochem.
, vol.101
, pp. 241-249
-
-
Oliveira, J.M.1
Jekabsons, M.B.2
Chen, S.3
Lin, A.4
Rego, A.C.5
Goncalves, J.6
Ellerby, L.M.7
Nicholls, D.G.8
-
15
-
-
0037066115
-
Regional and progressive thinning of the cortical ribbon in Huntington's disease
-
Rosas H.D., Liu A.K., Hersch S., Glessner M., Ferrante R.J., Salat D.H., van der K.A., Jenkins B.G., Dale A.M., Fischl B. Regional and progressive thinning of the cortical ribbon in Huntington's disease. Neurology 2002, 58:695-701.
-
(2002)
Neurology
, vol.58
, pp. 695-701
-
-
Rosas, H.D.1
Liu, A.K.2
Hersch, S.3
Glessner, M.4
Ferrante, R.J.5
Salat, D.H.6
van der, K.A.7
Jenkins, B.G.8
Dale, A.M.9
Fischl, B.10
-
16
-
-
24644479046
-
Regional cortical thinning in preclinical Huntington disease and its relationship to cognition
-
Rosas H.D., Hevelone N.D., Zaleta A.K., Greve D.N., Salat D.H., Fischl B. Regional cortical thinning in preclinical Huntington disease and its relationship to cognition. Neurology 2005, 65:745-747.
-
(2005)
Neurology
, vol.65
, pp. 745-747
-
-
Rosas, H.D.1
Hevelone, N.D.2
Zaleta, A.K.3
Greve, D.N.4
Salat, D.H.5
Fischl, B.6
-
17
-
-
0032051772
-
Chronic administration of quinolinic acid in the rat striatum causes spatial learning deficits in a radial arm water maze task
-
Shear D.A., Dong J., Haik-Creguer K.L., Bazzett T.J., Albin R.L., Dunbar G.L. Chronic administration of quinolinic acid in the rat striatum causes spatial learning deficits in a radial arm water maze task. Exp. Neurol. 1998, 150:305-311.
-
(1998)
Exp. Neurol.
, vol.150
, pp. 305-311
-
-
Shear, D.A.1
Dong, J.2
Haik-Creguer, K.L.3
Bazzett, T.J.4
Albin, R.L.5
Dunbar, G.L.6
-
18
-
-
0032949459
-
A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice
-
Shelbourne P.F., Killeen N., Hevner R.F., Johnston H.M., Tecott L., Lewandoski M., Ennis M., Ramirez L., Li Z., Iannicola C., Littman D.R., Myers R.M. A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice. Hum. Mol. Genet. 1999, 8:763-774.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 763-774
-
-
Shelbourne, P.F.1
Killeen, N.2
Hevner, R.F.3
Johnston, H.M.4
Tecott, L.5
Lewandoski, M.6
Ennis, M.7
Ramirez, L.8
Li, Z.9
Iannicola, C.10
Littman, D.R.11
Myers, R.M.12
-
19
-
-
10744227174
-
Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease
-
Slow E.J., van Raamsdonk J., Rogers D., Coleman S.H., Graham R.K., Deng Y., Oh R., Bissada N., Hossain S.M., Yang Y.Z., Li X.J., Simpson E.M., Gutekunst C.A., Leavitt B.R., Hayden M.R. Selective striatal neuronal loss in a YAC128 mouse model of Huntington disease. Hum. Mol. Genet. 2003, 12:1555-1567.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 1555-1567
-
-
Slow, E.J.1
van Raamsdonk, J.2
Rogers, D.3
Coleman, S.H.4
Graham, R.K.5
Deng, Y.6
Oh, R.7
Bissada, N.8
Hossain, S.M.9
Yang, Y.Z.10
Li, X.J.11
Simpson, E.M.12
Gutekunst, C.A.13
Leavitt, B.R.14
Hayden, M.R.15
-
20
-
-
33847715903
-
Verbal episodic memory declines prior to diagnosis in Huntington's disease
-
Solomon A.C., Stout J.C., Johnson S.A., Langbehn D.R., Aylward E.H., Brandt J., Ross C.A., Beglinger L., Hayden M.R., Kieburtz K., Kayson E., Julian-Baros E., Duff K., Guttman M., Nance M., Oakes D., Shoulson I., Penziner E., Paulsen J.S. Verbal episodic memory declines prior to diagnosis in Huntington's disease. Neuropsychologia 2007, 45:1767-1776.
-
(2007)
Neuropsychologia
, vol.45
, pp. 1767-1776
-
-
Solomon, A.C.1
Stout, J.C.2
Johnson, S.A.3
Langbehn, D.R.4
Aylward, E.H.5
Brandt, J.6
Ross, C.A.7
Beglinger, L.8
Hayden, M.R.9
Kieburtz, K.10
Kayson, E.11
Julian-Baros, E.12
Duff, K.13
Guttman, M.14
Nance, M.15
Oakes, D.16
Shoulson, I.17
Penziner, E.18
Paulsen, J.S.19
-
21
-
-
25844526181
-
Gene expression in Huntington's disease skeletal muscle: a potential biomarker
-
Strand A.D., Aragaki A.K., Shaw D., Bird T., Holton J., Turner C., Tapscott S.J., Tabrizi S.J., Schapira A.H., Kooperberg C., Olson J.M. Gene expression in Huntington's disease skeletal muscle: a potential biomarker. Hum. Mol. Genet. 2005, 14:1863-1876.
-
(2005)
Hum. Mol. Genet.
, vol.14
, pp. 1863-1876
-
-
Strand, A.D.1
Aragaki, A.K.2
Shaw, D.3
Bird, T.4
Holton, J.5
Turner, C.6
Tapscott, S.J.7
Tabrizi, S.J.8
Schapira, A.H.9
Kooperberg, C.10
Olson, J.M.11
-
22
-
-
0028958409
-
Impaired prepulse inhibition of acoustic and tactile startle response in patients with Huntington's disease
-
Swerdlow N.R., Paulsen J., Braff D.L., Butters N., Geyer M.A., Swenson M.R. Impaired prepulse inhibition of acoustic and tactile startle response in patients with Huntington's disease. J. Neurol. Neurosurg. Psychiatry 1995, 58:192-200.
-
(1995)
J. Neurol. Neurosurg. Psychiatry
, vol.58
, pp. 192-200
-
-
Swerdlow, N.R.1
Paulsen, J.2
Braff, D.L.3
Butters, N.4
Geyer, M.A.5
Swenson, M.R.6
-
23
-
-
14644440579
-
Neuronal intranuclear inclusions and neuropil aggregates in HdhCAG(150) knockin mice
-
Tallaksen-Greene S.J., Crouse A.B., Hunter J.M., Detloff P.J., Albin R.L. Neuronal intranuclear inclusions and neuropil aggregates in HdhCAG(150) knockin mice. Neuroscience 2005, 131:843-852.
-
(2005)
Neuroscience
, vol.131
, pp. 843-852
-
-
Tallaksen-Greene, S.J.1
Crouse, A.B.2
Hunter, J.M.3
Detloff, P.J.4
Albin, R.L.5
-
24
-
-
0027480960
-
A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
-
The Huntington's Disease Collaborative Research Group
-
The Huntington's Disease Collaborative Research Group A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993, 72:971-983.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
25
-
-
33947286031
-
Phenotypic abnormalities in the YAC128 mouse model of Huntington disease are penetrant on multiple genetic backgrounds and modulated by strain
-
Van Raamsdonk J.M., Metzler M., Slow E., Pearson J., Schwab C., Carroll J., Graham R.K., Leavitt B.R., Hayden M.R. Phenotypic abnormalities in the YAC128 mouse model of Huntington disease are penetrant on multiple genetic backgrounds and modulated by strain. Neurobiol. Dis. 2007, 26:189-200.
-
(2007)
Neurobiol. Dis.
, vol.26
, pp. 189-200
-
-
Van Raamsdonk, J.M.1
Metzler, M.2
Slow, E.3
Pearson, J.4
Schwab, C.5
Carroll, J.6
Graham, R.K.7
Leavitt, B.R.8
Hayden, M.R.9
-
26
-
-
0037444426
-
Transgenic rat model of Huntington's disease
-
von Horsten S., Schmitt I., Nguyen H.P., Holzmann C., Schmidt T., Walther T., Bader M., Pabst R., Kobbe P., Krotova J., Stiller D., Kask A., Vaarmann A., Rathke-Hartlieb S., Schulz J.B., Grasshoff U., Bauer I., Vieira-Saecker A.M., Paul M., Jones L., Lindenberg K.S., Landwehrmeyer B., Bauer A., Li X.J., Riess O. Transgenic rat model of Huntington's disease. Hum. Mol. Genet. 2003, 12:617-624.
-
(2003)
Hum. Mol. Genet.
, vol.12
, pp. 617-624
-
-
von Horsten, S.1
Schmitt, I.2
Nguyen, H.P.3
Holzmann, C.4
Schmidt, T.5
Walther, T.6
Bader, M.7
Pabst, R.8
Kobbe, P.9
Krotova, J.10
Stiller, D.11
Kask, A.12
Vaarmann, A.13
Rathke-Hartlieb, S.14
Schulz, J.B.15
Grasshoff, U.16
Bauer, I.17
Vieira-Saecker, A.M.18
Paul, M.19
Jones, L.20
Lindenberg, K.S.21
Landwehrmeyer, B.22
Bauer, A.23
Li, X.J.24
Riess, O.25
more..
-
28
-
-
0032938295
-
Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse
-
Wheeler V.C., Auerbach W., White J.K., Srinidhi J., Auerbach A., Ryan A., Duyao M.P., Vrbanac V., Weaver M., Gusella J.F., Joyner A.L., MacDonald M.E. Length-dependent gametic CAG repeat instability in the Huntington's disease knock-in mouse. Hum. Mol. Genet. 1999, 8:115-122.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 115-122
-
-
Wheeler, V.C.1
Auerbach, W.2
White, J.K.3
Srinidhi, J.4
Auerbach, A.5
Ryan, A.6
Duyao, M.P.7
Vrbanac, V.8
Weaver, M.9
Gusella, J.F.10
Joyner, A.L.11
MacDonald, M.E.12
-
29
-
-
0023237819
-
Impairments in the acquisition, retention and selection of spatial navigation strategies after medial caudate-putamen lesions in rats
-
Whishaw I.Q., Mittleman G., Bunch S.T., Dunnett S.B. Impairments in the acquisition, retention and selection of spatial navigation strategies after medial caudate-putamen lesions in rats. Behav. Brain Res. 1987, 24:125-138.
-
(1987)
Behav. Brain Res.
, vol.24
, pp. 125-138
-
-
Whishaw, I.Q.1
Mittleman, G.2
Bunch, S.T.3
Dunnett, S.B.4
-
30
-
-
33847684865
-
The Hdh(Q150/Q150) knock-in mouse model of HD and the R6/2 exon 1 model develop comparable and widespread molecular phenotypes
-
Woodman B., Butler R., Landles C., Lupton M.K., Tse J., Hockly E., Moffitt H., Sathasivam K., Bates G.P. The Hdh(Q150/Q150) knock-in mouse model of HD and the R6/2 exon 1 model develop comparable and widespread molecular phenotypes. Brain Res. Bull. 2007, 72:83-97.
-
(2007)
Brain Res. Bull.
, vol.72
, pp. 83-97
-
-
Woodman, B.1
Butler, R.2
Landles, C.3
Lupton, M.K.4
Tse, J.5
Hockly, E.6
Moffitt, H.7
Sathasivam, K.8
Bates, G.P.9
|