Differential effects of the huntington's disease CAG mutation in striatum and cerebellum are quantitative not qualitative

Human Molecular Genetics

Volumn 20, Issue 21, 2011, Pages 4258-4267

  Fossale, Elisa ^a   Seong, Ihn Sik ^a   Coser, Kathryn R ^b   Shioda, Toshi ^b   Kohane, Isaac S ^c,d   Wheeler, Vanessa C ^a   Gusella, James F ^a   Macdonald, Marcy E ^a   Lee, Jong Min ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL CANCER CENTER   (United States)

^c Harvard Medical School Center for Biomedical Informatics   (United States)

^d I2b2 National Center for Biomedical Computing   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUNTINGTIN; MUTANT PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CEREBELLUM; CONTROLLED STUDY; CORPUS STRIATUM; FEMALE; GENE EXPRESSION; GENE MUTATION; HUNTINGTON CHOREA; MALE; MOUSE; MOUSE MUTANT; NONHUMAN; PRIORITY JOURNAL; TISSUE SPECIFICITY;

ANIMALS; ASTROCYTES; BIOLOGICAL MARKERS; CEREBELLUM; GENE EXPRESSION REGULATION; GENE KNOCK-IN TECHNIQUES; HUNTINGTON DISEASE; MICE; MODELS, BIOLOGICAL; MUTANT PROTEINS; NEOSTRIATUM; NERVE TISSUE PROTEINS; NEURONS; NUCLEAR PROTEINS; ORGAN SPECIFICITY; RNA, MESSENGER; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SIGNAL TRANSDUCTION; TRINUCLEOTIDE REPEAT EXPANSION;

ANIMALIA; MUS;

EID: 80053969614     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr355     Document Type: Article

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