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Volumn 1151, Issue 1, 2007, Pages 219-226

Olfactory abnormalities in Huntington's disease: Decreased plasticity in the primary olfactory cortex of R6/1 transgenic mice and reduced olfactory discrimination in patients

Author keywords

DCX; Neurogenesis; Olfaction; Plasticity; Pyriform; R6 1; Stereology

Indexed keywords

DOUBLECORTIN; NERVE CELL ADHESION MOLECULE;

EID: 34248140136     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2007.03.018     Document Type: Article
Times cited : (59)

References (56)
  • 2
    • 26844446528 scopus 로고    scopus 로고
    • Neuronal plasticity, stress and depression: involvement of the cytoskeletal microtubular system?
    • Bianchi M., Hagan J.J., and Heidbreder C.A. Neuronal plasticity, stress and depression: involvement of the cytoskeletal microtubular system?. Curr. Drug Targets CNS Neurol. Disord. 4 5 (2005) 597-611
    • (2005) Curr. Drug Targets CNS Neurol. Disord. , vol.4 , Issue.5 , pp. 597-611
    • Bianchi, M.1    Hagan, J.J.2    Heidbreder, C.A.3
  • 4
    • 33750934187 scopus 로고    scopus 로고
    • PSA-NCAM in mammalian structural plasticity and neurogenesis
    • Bonfanti L. PSA-NCAM in mammalian structural plasticity and neurogenesis. Prog. Neurobiol 80 3 (2006) 129-164
    • (2006) Prog. Neurobiol , vol.80 , Issue.3 , pp. 129-164
    • Bonfanti, L.1
  • 8
    • 0035696339 scopus 로고    scopus 로고
    • Revisiting the function of PSA-NCAM in the nervous system
    • Durbec P., and Cremer H. Revisiting the function of PSA-NCAM in the nervous system. Mol. Neurobiol. 24 1-3 (2001) 53-64
    • (2001) Mol. Neurobiol. , vol.24 , Issue.1-3 , pp. 53-64
    • Durbec, P.1    Cremer, H.2
  • 9
    • 4644294031 scopus 로고    scopus 로고
    • Aging results in reduced epidermal growth factor receptor signaling, diminished olfactory neurogenesis, and deficits in fine olfactory discrimination
    • Enwere E., Shingo T., Gregg C., Fujikawa H., Ohta S., and Weiss S. Aging results in reduced epidermal growth factor receptor signaling, diminished olfactory neurogenesis, and deficits in fine olfactory discrimination. J. Neurosci. 24 38 (2004) 8354-8365
    • (2004) J. Neurosci. , vol.24 , Issue.38 , pp. 8354-8365
    • Enwere, E.1    Shingo, T.2    Gregg, C.3    Fujikawa, H.4    Ohta, S.5    Weiss, S.6
  • 12
    • 26944493771 scopus 로고    scopus 로고
    • A similar impairment in CA3 mossy fibre LTP in the R6/2 mouse model of Huntington's disease and in the complexin II knockout mouse
    • Gibson H.E., Reim K., Brose N., Morton A.J., and Jones S. A similar impairment in CA3 mossy fibre LTP in the R6/2 mouse model of Huntington's disease and in the complexin II knockout mouse. Eur. J. Neurosci. 22 7 (2005) 1701-1712
    • (2005) Eur. J. Neurosci. , vol.22 , Issue.7 , pp. 1701-1712
    • Gibson, H.E.1    Reim, K.2    Brose, N.3    Morton, A.J.4    Jones, S.5
  • 13
    • 2642545019 scopus 로고    scopus 로고
    • Asialo-erythropoietin is not effective in the R6/2 line of Huntington's disease mice
    • Gil J.M.A.C., Leist M., Popovic N., Brundin P., and Petersen A. Asialo-erythropoietin is not effective in the R6/2 line of Huntington's disease mice. BMC Neurosci. 5 (2004) 17
    • (2004) BMC Neurosci. , vol.5 , pp. 17
    • Gil, J.M.A.C.1    Leist, M.2    Popovic, N.3    Brundin, P.4    Petersen, A.5
  • 15
    • 0033152450 scopus 로고    scopus 로고
    • Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons
    • Gleeson J.G., Lin P.T., Flanagan L.A., and Walsh C.A. Doublecortin is a microtubule-associated protein and is expressed widely by migrating neurons. Neuron 23 2 (1999) 257-271
    • (1999) Neuron , vol.23 , Issue.2 , pp. 257-271
    • Gleeson, J.G.1    Lin, P.T.2    Flanagan, L.A.3    Walsh, C.A.4
  • 18
    • 0033383436 scopus 로고    scopus 로고
    • Odor detection, learning, and memory in Huntington's disease
    • Hamilton J.M., Murphy C., and Paulsen J.S. Odor detection, learning, and memory in Huntington's disease. J. Int. Neuropsychol. Soc. 5 7 (1999) 609-615
    • (1999) J. Int. Neuropsychol. Soc. , vol.5 , Issue.7 , pp. 609-615
    • Hamilton, J.M.1    Murphy, C.2    Paulsen, J.S.3
  • 19
    • 0033105173 scopus 로고    scopus 로고
    • Expression of doublecortin correlates with neuronal migration and pattern formation in diverse regions of the developing chick brain
    • Hannan A.J., Henke R.C., Seeto G.S., Capes-Davis A., Dunn J., and Jeffrey P.L. Expression of doublecortin correlates with neuronal migration and pattern formation in diverse regions of the developing chick brain. J. Neurosci. Res. 55 5 (1999) 650-657
    • (1999) J. Neurosci. Res. , vol.55 , Issue.5 , pp. 650-657
    • Hannan, A.J.1    Henke, R.C.2    Seeto, G.S.3    Capes-Davis, A.4    Dunn, J.5    Jeffrey, P.L.6
  • 21
    • 0030305457 scopus 로고    scopus 로고
    • R: a language for data analysis and graphics
    • Ihaka R., and Gentleman R. R: a language for data analysis and graphics. J. Comput. Graph. Stat. 5 (1996) 299-314
    • (1996) J. Comput. Graph. Stat. , vol.5 , pp. 299-314
    • Ihaka, R.1    Gentleman, R.2
  • 22
    • 3242754970 scopus 로고    scopus 로고
    • Linking the synapse to the cytoskeleton: a breath-taking role for microfilaments
    • Jockusch B.M., Rothkegel M., and Schwarz G. Linking the synapse to the cytoskeleton: a breath-taking role for microfilaments. NeuroReport 15 10 (2004) 1535-1538
    • (2004) NeuroReport , vol.15 , Issue.10 , pp. 1535-1538
    • Jockusch, B.M.1    Rothkegel, M.2    Schwarz, G.3
  • 23
    • 33744983538 scopus 로고    scopus 로고
    • Stress effects in the hippocampus: synaptic plasticity and memory
    • Kim J.J., Song E.Y., and Kosten T.A. Stress effects in the hippocampus: synaptic plasticity and memory. Stress 9 1 (2006) 1-11
    • (2006) Stress , vol.9 , Issue.1 , pp. 1-11
    • Kim, J.J.1    Song, E.Y.2    Kosten, T.A.3
  • 24
    • 0035214922 scopus 로고    scopus 로고
    • Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice
    • Klapstein G.J., Fisher R.S., Zanjani H., Cepeda C., Jokel E.S., Chesselet M.F., and Levine M.S. Electrophysiological and morphological changes in striatal spiny neurons in R6/2 Huntington's disease transgenic mice. J. Neurophysiol. 86 6 (2001) 2667-2677
    • (2001) J. Neurophysiol. , vol.86 , Issue.6 , pp. 2667-2677
    • Klapstein, G.J.1    Fisher, R.S.2    Zanjani, H.3    Cepeda, C.4    Jokel, E.S.5    Chesselet, M.F.6    Levine, M.S.7
  • 25
    • 0001418665 scopus 로고
    • The histochemical identification of acetylcholinesterase in cholinergic, adrenergic and sensory neurons
    • Koelle G.B. The histochemical identification of acetylcholinesterase in cholinergic, adrenergic and sensory neurons. J. Pharmacol. Exp. Ther. 114 2 (1955) 167-184
    • (1955) J. Pharmacol. Exp. Ther. , vol.114 , Issue.2 , pp. 167-184
    • Koelle, G.B.1
  • 26
    • 33645452859 scopus 로고    scopus 로고
    • Neurogenesis in the R6/1 transgenic mouse model of Huntington's disease: effects of environmental enrichment
    • Lazic S.E., Grote H.E., Blakemore C., Hannan A.J., van Dellen A., Phillips W., and Barker R.A. Neurogenesis in the R6/1 transgenic mouse model of Huntington's disease: effects of environmental enrichment. Eur. J. Neurosci. 23 7 (2006) 1829-1838
    • (2006) Eur. J. Neurosci. , vol.23 , Issue.7 , pp. 1829-1838
    • Lazic, S.E.1    Grote, H.E.2    Blakemore, C.3    Hannan, A.J.4    van Dellen, A.5    Phillips, W.6    Barker, R.A.7
  • 28
    • 0036734833 scopus 로고    scopus 로고
    • Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice
    • Lee J., Duan W., and Mattson M.P. Evidence that brain-derived neurotrophic factor is required for basal neurogenesis and mediates, in part, the enhancement of neurogenesis by dietary restriction in the hippocampus of adult mice. J. Neurochem. 82 6 (2002) 1367-1375
    • (2002) J. Neurochem. , vol.82 , Issue.6 , pp. 1367-1375
    • Lee, J.1    Duan, W.2    Mattson, M.P.3
  • 29
    • 0033500593 scopus 로고    scopus 로고
    • Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation
    • Lione L.A., Carter R.J., Hunt M.J., Bates G.P., Morton A.J., and Dunnett S.B. Selective discrimination learning impairments in mice expressing the human Huntington's disease mutation. J. Neurosci. 19 23 (1999) 10428-10437
    • (1999) J. Neurosci. , vol.19 , Issue.23 , pp. 10428-10437
    • Lione, L.A.1    Carter, R.J.2    Hunt, M.J.3    Bates, G.P.4    Morton, A.J.5    Dunnett, S.B.6
  • 30
    • 0242300063 scopus 로고    scopus 로고
    • Glia-independent chains of neuroblasts through the subcortical parenchyma of the adult rabbit brain
    • Luzzati F., Peretto P., Aimar P., Ponti G., Fasolo A., and Bonfanti L. Glia-independent chains of neuroblasts through the subcortical parenchyma of the adult rabbit brain. Proc. Natl. Acad. Sci. U. S. A. 100 22 (2003) 13036-13041
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , Issue.22 , pp. 13036-13041
    • Luzzati, F.1    Peretto, P.2    Aimar, P.3    Ponti, G.4    Fasolo, A.5    Bonfanti, L.6
  • 31
  • 33
    • 16244392082 scopus 로고    scopus 로고
    • Deficits in experience-dependent cortical plasticity and sensory-discrimination learning in presymptomatic Huntington's disease mice
    • Mazarakis N.K., Cybulska-Klosowicz A., Grote H., Pang T., Dellen A.V., Kossut M., Blakemore C., and Hannan A.J. Deficits in experience-dependent cortical plasticity and sensory-discrimination learning in presymptomatic Huntington's disease mice. J. Neurosci. 25 12 (2005) 3059-3066
    • (2005) J. Neurosci. , vol.25 , Issue.12 , pp. 3059-3066
    • Mazarakis, N.K.1    Cybulska-Klosowicz, A.2    Grote, H.3    Pang, T.4    Dellen, A.V.5    Kossut, M.6    Blakemore, C.7    Hannan, A.J.8
  • 35
    • 0030919889 scopus 로고    scopus 로고
    • Olfactory function in Huntington's disease patients and atrisk offspring
    • Moberg P.J., and Doty R.L. Olfactory function in Huntington's disease patients and atrisk offspring. Int. J. Neurosci. 89 1-2 (1997) 133-139
    • (1997) Int. J. Neurosci. , vol.89 , Issue.1-2 , pp. 133-139
    • Moberg, P.J.1    Doty, R.L.2
  • 37
    • 0034234519 scopus 로고    scopus 로고
    • Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation
    • Murphy K.P., Carter R.J., Lione L.A., Mangiarini L., Mahal A., Bates G.P., Dunnett S.B., and Morton A.J. Abnormal synaptic plasticity and impaired spatial cognition in mice transgenic for exon 1 of the human Huntington's disease mutation. J. Neurosci. 20 13 (2000) 5115-5123
    • (2000) J. Neurosci. , vol.20 , Issue.13 , pp. 5115-5123
    • Murphy, K.P.1    Carter, R.J.2    Lione, L.A.3    Mangiarini, L.4    Mahal, A.5    Bates, G.P.6    Dunnett, S.B.7    Morton, A.J.8
  • 38
    • 0036283521 scopus 로고    scopus 로고
    • Doublecortin expression in the adult rat telencephalon
    • Nacher J., Crespo C., and McEwen B.S. Doublecortin expression in the adult rat telencephalon. Eur. J. Neurosci. 14 4 (2001) 629-644
    • (2001) Eur. J. Neurosci. , vol.14 , Issue.4 , pp. 629-644
    • Nacher, J.1    Crespo, C.2    McEwen, B.S.3
  • 39
    • 2942666062 scopus 로고    scopus 로고
    • Chronic restraint stress and chronic corticosterone treatment modulate differentially the expression of molecules related to structural plasticity in the adult rat piriform cortex
    • Nacher J., Pham K., Gil-Fernandez V., and McEwen B.S. Chronic restraint stress and chronic corticosterone treatment modulate differentially the expression of molecules related to structural plasticity in the adult rat piriform cortex. Neuroscience 126 2 (2004) 503-509
    • (2004) Neuroscience , vol.126 , Issue.2 , pp. 503-509
    • Nacher, J.1    Pham, K.2    Gil-Fernandez, V.3    McEwen, B.S.4
  • 40
    • 27244445804 scopus 로고    scopus 로고
    • Chronic BDNF deficiency permanently modifies excitatory synapses in the piriform cortex
    • Nanobashvili A., Jakubs K., and Kokaia M. Chronic BDNF deficiency permanently modifies excitatory synapses in the piriform cortex. J. Neurosci. Res. 81 5 (2005) 696-705
    • (2005) J. Neurosci. Res. , vol.81 , Issue.5 , pp. 696-705
    • Nanobashvili, A.1    Jakubs, K.2    Kokaia, M.3
  • 41
    • 0029295099 scopus 로고
    • Sensory- and memory-mediated olfactory dysfunction in Huntington's disease
    • Nordin S., Paulsen J.S., and Murphy C. Sensory- and memory-mediated olfactory dysfunction in Huntington's disease. J. Int. Neuropsychol. Soc. 1 3 (1995) 281-290
    • (1995) J. Int. Neuropsychol. Soc. , vol.1 , Issue.3 , pp. 281-290
    • Nordin, S.1    Paulsen, J.S.2    Murphy, C.3
  • 43
    • 33646361842 scopus 로고    scopus 로고
    • Neurogenesis in the adult rat piriform cortex
    • Pekcec A., Loscher W., and Potschka H. Neurogenesis in the adult rat piriform cortex. NeuroReport 17 6 (2006) 571-574
    • (2006) NeuroReport , vol.17 , Issue.6 , pp. 571-574
    • Pekcec, A.1    Loscher, W.2    Potschka, H.3
  • 44
    • 30744470119 scopus 로고    scopus 로고
    • Abnormalities of neurogenesis in the R6/2 mouse model of Huntington's disease are attributable to the in vivo microenvironment
    • Phillips W., Morton A.J., and Barker R.A. Abnormalities of neurogenesis in the R6/2 mouse model of Huntington's disease are attributable to the in vivo microenvironment. J. Neurosci. 25 50 (2005) 11564-11576
    • (2005) J. Neurosci. , vol.25 , Issue.50 , pp. 11564-11576
    • Phillips, W.1    Morton, A.J.2    Barker, R.A.3
  • 45
    • 33749019984 scopus 로고    scopus 로고
    • Limbic neurogenesis/plasticity in the R6/2 mouse model of Huntington's disease
    • Phillips W., Morton A.J., and Barker R. Limbic neurogenesis/plasticity in the R6/2 mouse model of Huntington's disease. NeuroReport 17 15 (2006) 1623-1627
    • (2006) NeuroReport , vol.17 , Issue.15 , pp. 1623-1627
    • Phillips, W.1    Morton, A.J.2    Barker, R.3
  • 46
    • 0842330444 scopus 로고    scopus 로고
    • Efficacy of doublecortin as a marker to analyse the absolute number and dendritic growth of newly generated neurons in the adult dentate gyrus
    • Rao M.S., and Shetty A.K. Efficacy of doublecortin as a marker to analyse the absolute number and dendritic growth of newly generated neurons in the adult dentate gyrus. Eur. J. Neurosci. 19 2 (2004) 234-246
    • (2004) Eur. J. Neurosci. , vol.19 , Issue.2 , pp. 234-246
    • Rao, M.S.1    Shetty, A.K.2
  • 48
    • 0030270037 scopus 로고    scopus 로고
    • Polysialic acid in the vertebrate nervous system: a promoter of plasticity in cell cell interactions
    • Rutishauser U., and Landmesser L. Polysialic acid in the vertebrate nervous system: a promoter of plasticity in cell cell interactions. Trends Neurosci. 19 10 (1996) 422-427
    • (1996) Trends Neurosci. , vol.19 , Issue.10 , pp. 422-427
    • Rutishauser, U.1    Landmesser, L.2
  • 50
    • 1542286877 scopus 로고    scopus 로고
    • Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism
    • Spires T.L., Grote H.E., Varshney N.K., Cordery P.M., van Dellen A., Blakemore C., and Hannan A.J. Environmental enrichment rescues protein deficits in a mouse model of Huntington's disease, indicating a possible disease mechanism. J. Neurosci. 24 9 (2004) 2270-2276
    • (2004) J. Neurosci. , vol.24 , Issue.9 , pp. 2270-2276
    • Spires, T.L.1    Grote, H.E.2    Varshney, N.K.3    Cordery, P.M.4    van Dellen, A.5    Blakemore, C.6    Hannan, A.J.7
  • 51
    • 0038185148 scopus 로고    scopus 로고
    • The fundamental role of memory in olfactory perception
    • Wilson D.A., and Stevenson R.J. The fundamental role of memory in olfactory perception. Trends Neurosci. 26 5 (2003) 243-247
    • (2003) Trends Neurosci. , vol.26 , Issue.5 , pp. 243-247
    • Wilson, D.A.1    Stevenson, R.J.2
  • 52
    • 0034799923 scopus 로고    scopus 로고
    • Scopolamine enhances generalization between odor representations in rat olfactory cortex
    • Wilson D.A. Scopolamine enhances generalization between odor representations in rat olfactory cortex. Learn. Mem. 8 5 (2001) 279-285
    • (2001) Learn. Mem. , vol.8 , Issue.5 , pp. 279-285
    • Wilson, D.A.1
  • 53
    • 24144439085 scopus 로고    scopus 로고
    • Roles of mineralocorticoid and glucocorticoid receptors in the regulation of progenitor proliferation in the adult hippocampus
    • Wong E.Y.H., and Herbert J. Roles of mineralocorticoid and glucocorticoid receptors in the regulation of progenitor proliferation in the adult hippocampus. Eur. J. Neurosci. 22 4 (2005) 785-792
    • (2005) Eur. J. Neurosci. , vol.22 , Issue.4 , pp. 785-792
    • Wong, E.Y.H.1    Herbert, J.2
  • 54
    • 29744434761 scopus 로고    scopus 로고
    • Raised circulating corticosterone inhibits neuronal differentiation of progenitor cells in the adult hippocampus
    • Wong E.Y.H., and Herbert J. Raised circulating corticosterone inhibits neuronal differentiation of progenitor cells in the adult hippocampus. Neuroscience 137 1 (2006) 83-92
    • (2006) Neuroscience , vol.137 , Issue.1 , pp. 83-92
    • Wong, E.Y.H.1    Herbert, J.2


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