SCOPUS 정보 검색 플랫폼

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 56, Issue 9-10, 2013, Pages 513-519

Preparation of labeled human drugmetabolites and drug-drug interaction-probes with fungal peroxygenases

(7) Poraj Kobielska, Marzena a Atzrodt, Jens b Holla, Wolfgang b Sandvoss, Martin b Gröbe, Glenn c Scheibner, Katrin c Hofrichter, Martin a

a International Graduate School Zittau (Germany)

b SANOFI AVENTIS DEUTSCHLAND GMBH (Germany)

c Lausitz University of Applied Sciences (Germany)

Author keywords

4'OH diclofenac; Deuterium; EC 1.11.2.1; H D exchange; Human drug metabolites; Isotopic labeled synthesis; Lidocaine; Paracetamol; Phenacetin; Unspecific aromatic peroxygenase

Indexed keywords

BIOMOLECULES; DRUG INTERACTIONS; ENZYMES; METABOLITES; OXYGEN; SUBSTRATES; SYNTHESIS (CHEMICAL); TECHNOLOGY TRANSFER;

4'OH-DICLOFENAC; DICLOFENAC; DRUG METABOLITES; EC 1.11.2.1; H-D EXCHANGE; HUMAN DRUG METABOLITE; ISOTOPIC LABELED SYNTHESIS; LIDOCAINE; OH -; PARACETAMOL; PHENACETIN; UNSPECIFIC/ AROMATIC PEROXYGENASE;

DEUTERIUM;

4' HYDROXYDICLOFENAC; CYTOCHROME P450; DICLOFENAC; DICLOFENAC D7; DICLOFENAC DERIVATIVE; DRUG METABOLITE; FUNGAL ENZYME; KETOPROFEN; LIDOCAINE; PHENACETIN; UNCLASSIFIED DRUG; UNSPECIFIC PEROXYGENASE;

ARTICLE; CONTROLLED STUDY; DEALKYLATION; DEUTERIUM HYDROGEN EXCHANGE; ELUTION; ENZYME METABOLISM; ENZYME STABILITY; EPOXIDATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HYDROXYLATION; ISOTOPE LABELING; MOLECULAR PROBE; NONHUMAN; REACTION ANALYSIS; SYNTHESIS;

4'OH-DICLOFENAC; DEUTERIUM; EC 1.11.2.1; H/D EXCHANGE; HUMAN DRUG METABOLITES; ISOTOPIC LABELED SYNTHESIS; LIDOCAINE; PARACETAMOL; PHENACETIN; UNSPECIFIC/AROMATIC PEROXYGENASE;

AGARICALES; DEUTERIUM EXCHANGE MEASUREMENT; DRUG INTERACTIONS; HUMANS; HYDROXYLATION; MIXED FUNCTION OXYGENASES; MOLECULAR PROBES; PHARMACEUTICAL PREPARATIONS;

EID: 84894348429 PISSN: 03624803 EISSN: 10991344 Source Type: Journal
DOI: 10.1002/jlcr.3103 Document Type: Article

Times cited : (15)

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