A predictably selective aliphatic C-H oxidation reaction for complex molecule synthesis

Science

Volumn 318, Issue 5851, 2007, Pages 783-787

  Chen, Mark S ^a   White, M Christina ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALIPHATIC COMPOUND; CARBON; CARBOXYLIC ACID; HYDROGEN; HYDROGEN PEROXIDE; IRON; LACTONE;

ALIPHATIC HYDROCARBON; CARBON; CATALYSIS; HYDROGEN; HYDROGEN PEROXIDE; OXIDATION; PREDICTION;

ARTICLE; CATALYST; CHEMICAL BOND; MOLECULE; OXIDATION; PREDICTION; PRIORITY JOURNAL; SYNTHESIS;

EID: 40949096433     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1148597     Document Type: Article

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30. We gratefully acknowledge J. Baudry for DFT calculations, S. Wilson for x-ray crystallographic analysis, M. A. Bigi and D. J. Covell for checking our experimental procedure, and S. E. Denmark and C. S. Regens for a gift of (S,S)-2,2′-bipyrrolidine tartrate. M.S.C. is a Harvard University graduate student completing doctoral work with M.C.W. at University of Illinois at Urbana-Champaign. We are grateful to the A.P. Sloan Foundation, the Camille and Henry Dreyfus Foundation, and the University of Illinois for financial support. M.C.W is a 2007 Lilly Grantee Award recipient. Supplementary crystallographic data for this paper can be obtained from the Cambridge Crystallographic Data Centre via www.ccdc.cam.ac.uk/data_request/cif on quoting registry nos. CCDC-661933 for 4, CCDC-661935 for (-)-36, CCDC-661934 for (+)-37, and CCDC-661936 for (+)-38.