Pd- and Pt-catalyzed H/D exchange methods and their application for internal MS standard preparation from a Sanofi-Aventis perspective

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 53, Issue 11-12, 2010, Pages 674-685

  Atzrodt, Jens ^a   Derdau, Volker ^a  

^a SANOFI AVENTIS DEUTSCHLAND GMBH   (Germany)

Author keywords

catalysis; deuterium; H D exchange; palladium; platinum

Indexed keywords

CATALYSIS; PALLADIUM;

CATALYST ACTIVATION; EXCHANGE METHODS; H-D EXCHANGE; ISOTOPICALLY LABELED; METHOD DEVELOPMENT; PT-CATALYZED; SANOFI-AVENTIS;

PLATINUM;

ALIPHATIC HYDROCARBON; CARBAZOLE DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; FERROQUINE; FOLIC ACID DERIVATIVE; FORMOTEROL FUMARATE; HYDROGEN; IBUPROFEN; PALLADIUM; PALLADIUM COMPLEX; PLATINUM; PYRIMIDINE INDOLE 5 CARBOXYLIC ACID DERIVATIVE; QUINOXALINE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; ASTHMA; BRONCHITIS; CATALYSIS; CATALYST; CHEMICAL ANALYSIS; CHROMATOGRAPHY; DECARBOXYLATION; DEUTERIUM HYDROGEN EXCHANGE; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROGENOLYSIS; ISOTOPE LABELING; MICROWAVE IRRADIATION; MOLECULAR WEIGHT; NUCLEAR MAGNETIC RESONANCE; REACTION TIME; ROOM TEMPERATURE; STEREOCHEMISTRY; SUBSTITUTION REACTION; SYNTHESIS; TANDEM MASS SPECTROMETRY;

EID: 78650487017     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1818     Document Type: Article

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