The use of biocatalysis in the synthesis of labelled compounds

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 50, Issue 5-6, 2007, Pages 342-346

  Allen, John ^a   Brasseur, Denis M ^a   De Bruin, Béatrice ^a   Denoux, Mireille ^a   Pérard, Serge ^a   Philippe, Nicolas ^a   Roy, Sébastien N ^a  

^a SANOFI   (France)

Author keywords

Biocatalysis; Biotransformation; CYP450; Isotope labelling; Microorganisms; Nitrilase; Nitrile hydratase

Indexed keywords

CATALYSIS; CYANIDES; ENZYMES; HYDROLYSIS;

BIOCATALYSIS; BIOTRANSFORMATION; CATALYTIC PROPERTIES; CYTOCHROMES P450; ISOTOPE LABELING; NITRILASE; NITRILE HYDRATASES; ORGANIC CHEMISTRY; REGIO-SELECTIVE; STEREO-SELECTIVE;

MICROORGANISMS;

CARBON 14; CYTOCHROME P450; MIDAZOLAM; N TERT BUTYL 4 [5' ETHOXY 4 (2 MORPHOLINOETHOXY) 2' OXOSPIRO[CYCLOHEXANE 1,3' INDOLE] 1' SULFONYL] 3 METHOXYBENZAMIDE H2 3; NITRILE; RADIOPHARMACEUTICAL AGENT; TRITIUM; UNCLASSIFIED DRUG;

CATALYSIS; COMPLEX FORMATION; CONFERENCE PAPER; CONTROLLED STUDY; DEALKYLATION; DRUG SYNTHESIS; ENZYME ACTIVITY; HYDROLYSIS; HYDROXYLATION; ISOTOPE LABELING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY;

EID: 34548163587     PISSN: 03624803     EISSN: 10991344     Source Type: Journal    
DOI: 10.1002/jlcr.1388     Document Type: Conference Paper

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