메뉴 건너뛰기




Volumn 20, Issue 2, 2014, Pages 189-200

Correlation between potassium channel expression and sensitivity to drug-induced cell death in tumor cell lines

Author keywords

Apoptosis; Chemotherapeutic drugs; Kv1.3 inhibitors; Mitochondria; Potassium channels

Indexed keywords

CERAMIDE; CISPLATIN; CLOFAZIMINE; POTASSIUM CHANNEL KV1.1; POTASSIUM CHANNEL KV1.3; STAUROSPORINE;

EID: 84892959692     PISSN: 13816128     EISSN: 18734286     Source Type: Journal    
DOI: 10.2174/13816128113199990032     Document Type: Article
Times cited : (64)

References (95)
  • 1
    • 8144228615 scopus 로고    scopus 로고
    • Voltage-gated potassium channels in cell proliferation
    • Pardo LA. Voltage-gated potassium channels in cell proliferation. Physiology (Bethesda) 2004; 19: 285-92.
    • (2004) Physiology (Bethesda) , vol.19 , pp. 285-292
    • Pardo, L.A.1
  • 2
    • 0034535126 scopus 로고    scopus 로고
    • Cell volume in the regulation of cell proliferation and apoptotic cell death
    • Lang F, Ritter M, Gamper N, et al. Cell volume in the regulation of cell proliferation and apoptotic cell death. Cell Physiol Biochem 2000; 10: 417-28.
    • (2000) Cell Physiol Biochem , vol.10 , pp. 417-428
    • Lang, F.1    Ritter, M.2    Gamper, N.3
  • 3
    • 11844307184 scopus 로고    scopus 로고
    • + channels in regulating tumour cell proliferation and apoptosis
    • + channels in regulating tumour cell proliferation and apoptosis. Pflugers Arch 2004; 448: 274-86.
    • (2004) Pflugers Arch , vol.448 , pp. 274-286
    • Wang, Z.1
  • 4
    • 29844437655 scopus 로고    scopus 로고
    • International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels
    • Gutman GA, Chandy KG, Grissmer S, et al. International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels. Pharmacol Rev 2005; 57: 473-508.
    • (2005) Pharmacol Rev , vol.57 , pp. 473-508
    • Gutman, G.A.1    Chandy, K.G.2    Grissmer, S.3
  • 5
    • 70349162817 scopus 로고    scopus 로고
    • The functional network of ion channels in T lymphocytes
    • Cahalan MD, Chandy KG. The functional network of ion channels in T lymphocytes. Immunol Rev 2009; 231: 59-87.
    • (2009) Immunol Rev , vol.231 , pp. 59-87
    • Cahalan, M.D.1    Chandy, K.G.2
  • 8
    • 84863473765 scopus 로고    scopus 로고
    • Inhibitors of mitochondrial Kv1. 3 channels induce Bax/Bak-independent death of cancer cells
    • Leanza L, Henry B, Sassi N, et al. Inhibitors of mitochondrial Kv1. 3 channels induce Bax/Bak-independent death of cancer cells. EMBO Mol Med 2012; 4: 577-93.
    • (2012) EMBO Mol Med , vol.4 , pp. 577-593
    • Leanza, L.1    Henry, B.2    Sassi, N.3
  • 9
    • 78650679914 scopus 로고    scopus 로고
    • Anti-proliferative effect of Kv1. 3 blockers in A549 human lung adenocarcinoma in vitro and in vivo
    • Jang SH, Choi SY, Ryu PS, Lee SY. Anti-proliferative effect of Kv1. 3 blockers in A549 human lung adenocarcinoma in vitro and in vivo. Eur J Pharmacol 2011; 651: 26-32.
    • (2011) Eur J Pharmacol , vol.651 , pp. 26-32
    • Jang, S.H.1    Choi, S.Y.2    Ryu, P.S.3    Lee, S.Y.4
  • 10
    • 77952671757 scopus 로고    scopus 로고
    • Contribution of voltage-gated potassium channels to the regulation of apoptosis
    • Szabò I, Zoratti M, Gulbins E. Contribution of voltage-gated potassium channels to the regulation of apoptosis. FEBS Lett 2010; 584: 2049-55.
    • (2010) FEBS Lett , vol.584 , pp. 2049-2055
    • Szabò, I.1    Zoratti, M.2    Gulbins, E.3
  • 12
    • 84856695390 scopus 로고    scopus 로고
    • Physiology of potassium channels in the inner membrane of mitochondria
    • Szabò I, Leanza L, Gulbins E, Zoratti M. Physiology of potassium channels in the inner membrane of mitochondria. Pflugers Arch 2012; 463: 231-46.
    • (2012) Pflugers Arch , vol.463 , pp. 231-246
    • Szabò, I.1    Leanza, L.2    Gulbins, E.3    Zoratti, M.4
  • 13
    • 84864403868 scopus 로고    scopus 로고
    • Evidence for mitoxantrone-induced block of inwardly rectifying K(+) channels expressed in the osteoclast precursor RAW 264. 7 cells differentiated with lipopolysaccharide
    • Wang CL, Tsai ML, Wu SN. Evidence for mitoxantrone-induced block of inwardly rectifying K(+) channels expressed in the osteoclast precursor RAW 264. 7 cells differentiated with lipopolysaccharide. Cell Physiol Biochem 2012; 30: 687-701.
    • (2012) Cell Physiol Biochem , vol.30 , pp. 687-701
    • Wang, C.L.1    Tsai, M.L.2    Wu, S.N.3
  • 14
    • 83755225880 scopus 로고    scopus 로고
    • Cholesterol depletion with (2-hydroxypropyl)-cyclodextrin modifies the gating of membrane electroporation-induced inward current in pituitary tumor GH3 cells: Experimental and analytical studies
    • Wu SN, Yeh CC, Huang HC, Yang WH. Cholesterol depletion with (2-hydroxypropyl)-cyclodextrin modifies the gating of membrane electroporation-induced inward current in pituitary tumor GH3 cells: experimental and analytical studies. Cell Physiol Biochem 2011; 28: 959-68.
    • (2011) Cell Physiol Biochem , vol.28 , pp. 959-968
    • Wu, S.N.1    Yeh, C.C.2    Huang, H.C.3    Yang, W.H.4
  • 15
    • 80052338033 scopus 로고    scopus 로고
    • Novel roles for hERG K(+) channels in cell proliferation and apoptosis
    • Aug 18
    • Jehle J, Schweizer PA, Katus HA, Thomas D. Novel roles for hERG K(+) channels in cell proliferation and apoptosis. Cell Death Dis 2011 Aug 18; 2: e193.
    • (2011) Cell Death Dis , vol.2
    • Jehle, J.1    Schweizer, P.A.2    Katus, H.A.3    Thomas, D.4
  • 16
    • 73449119314 scopus 로고    scopus 로고
    • Voltage-gated potassium channels as therapeutic targets
    • Wulff H, Castle NA, Pardo LA. Voltage-gated potassium channels as therapeutic targets. Nat Rev Drug Discov 2009; 8: 982-1001.
    • (2009) Nat Rev Drug Discov , vol.8 , pp. 982-1001
    • Wulff, H.1    Castle, N.A.2    Pardo, L.A.3
  • 17
    • 73949132375 scopus 로고    scopus 로고
    • Potassium channel regulator KCNRG regulates surface expression of Shaker-type potassium channels
    • Usman H, Mathew MK Potassium channel regulator KCNRG regulates surface expression of Shaker-type potassium channels. Biochem Biophys Res Commun 2010; 391: 1301-5.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 1301-1305
    • Usman, H.1    Mathew, M.K.2
  • 18
    • 84863838923 scopus 로고    scopus 로고
    • N-glycosylation promotes the cell surface expression of Kv1. 3 potassium channels
    • Zhu J, Yan J, Thornhill WB. N-glycosylation promotes the cell surface expression of Kv1. 3 potassium channels. FEBS J 2012; 279: 2632-44.
    • (2012) FEBS J , vol.279 , pp. 2632-2644
    • Zhu, J.1    Yan, J.2    Thornhill, W.B.3
  • 19
    • 70350366606 scopus 로고    scopus 로고
    • KCNE4 suppresses Kv1. 3 currents by modulating trafficking, surface expression and channel gating
    • Solé L, Roura-Ferrer M, Pérez-Verdaguer M, et al. KCNE4 suppresses Kv1. 3 currents by modulating trafficking, surface expression and channel gating. J Cell Sci 2009; 122: 3738-48.
    • (2009) J Cell Sci , vol.122 , pp. 3738-3748
    • Solé, L.1    Roura-Ferrer, M.2    Pérez-Verdaguer, M.3
  • 20
    • 84874771897 scopus 로고    scopus 로고
    • 3 potassium channel is regulated by the pro-domain of a matrix metalloprotease. J Biol Chem Jan 11, in press
    • Nguyen HM, Galea CA, Schmunk G, et al. Intracellular trafficking of the KV1. 3 potassium channel is regulated by the pro-domain of a matrix metalloprotease. J Biol Chem 2013 Jan 11, in press.
    • (2013) Intracellular trafficking of the KV1
    • Nguyen, H.M.1    Galea, C.A.2    Schmunk, G.3
  • 21
    • 0029810967 scopus 로고    scopus 로고
    • + channel in T lymphocytes upon Fas stimulation
    • + channel in T lymphocytes upon Fas stimulation. J Biol Chem 1996; 271: 20465-9.
    • (1996) J Biol Chem , vol.271 , pp. 20465-20469
    • Szabò, I.1    Gulbins, E.2    Apfel, H.3
  • 22
    • 35748976248 scopus 로고    scopus 로고
    • Cell volume regulatory ion channels in cell proliferation and cell death
    • Lang F, Föller M, Lang K, et al. Cell volume regulatory ion channels in cell proliferation and cell death. Methods Enzymol 2007; 428: 209-25.
    • (2007) Methods Enzymol , vol.428 , pp. 209-225
    • Lang, F.1    Föller, M.2    Lang, K.3
  • 23
    • 84869210513 scopus 로고    scopus 로고
    • Differential role of IK and BK potassium channels as mediators of intrinsic and extrinsic apoptotic cell death
    • McFerrin MB, Turner KL, Cuddapah VA, Sontheimer H. Differential role of IK and BK potassium channels as mediators of intrinsic and extrinsic apoptotic cell death. Am J Physiol Cell Physiol 2012; 303: C1070-8.
    • (2012) Am J Physiol Cell Physiol , vol.303 , pp. 1070-1078
    • McFerrin, M.B.1    Turner, K.L.2    Cuddapah, V.A.3    Sontheimer, H.4
  • 24
    • 51149089082 scopus 로고    scopus 로고
    • Mitochondrial potassium channel Kv1. 3 mediates Bax-induced apoptosis in lymphocytes
    • Szabó I, Bock J, Grassmé H, et al. Mitochondrial potassium channel Kv1. 3 mediates Bax-induced apoptosis in lymphocytes. Proc Natl Acad Sci USA 2008; 105: 14861-6.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 14861-14866
    • Szabó, I.1    Bock, J.2    Grassmé, H.3
  • 25
    • 77449149726 scopus 로고    scopus 로고
    • Kv1. 1 and Kv1. 3 channels contribute to the degeneration of retinal ganglion cells after optic nerve transection in vivo
    • Koeberle PD, Wang Y, Schlichter LC. Kv1. 1 and Kv1. 3 channels contribute to the degeneration of retinal ganglion cells after optic nerve transection in vivo. Cell Death Differ 2010; 17: 134-44.
    • (2010) Cell Death Differ , vol.17 , pp. 134-144
    • Koeberle, P.D.1    Wang, Y.2    Schlichter, L.C.3
  • 26
    • 48249146171 scopus 로고    scopus 로고
    • Kv1. 1 is associated with neuronal apoptosis and modulated by protein kinase C in the rat cerebellar granule cell
    • Hu CL, Zeng XM, Zhou MH, Shi YT, Cao H, Mei YA. Kv1. 1 is associated with neuronal apoptosis and modulated by protein kinase C in the rat cerebellar granule cell. J Neurochem 2008; 106: 1125-37.
    • (2008) J Neurochem , vol.106 , pp. 1125-1137
    • Hu, C.L.1    Zeng, X.M.2    Zhou, M.H.3    Shi, Y.T.4    Cao, H.5    Mei, Y.A.6
  • 27
    • 70449470623 scopus 로고    scopus 로고
    • Contribution of Kv channel subunits to glutamate-induced apoptosis in cultured rat hippocampal neurons
    • Shen QJ, Zhao YM, Cao DX, Wang XL. Contribution of Kv channel subunits to glutamate-induced apoptosis in cultured rat hippocampal neurons. J Neurosci Res 2009; 87: 3153-60.
    • (2009) J Neurosci Res , vol.87 , pp. 3153-3160
    • Shen, Q.J.1    Zhao, Y.M.2    Cao, D.X.3    Wang, X.L.4
  • 28
    • 0041932216 scopus 로고    scopus 로고
    • Potassium channel gene therapy can prevent neuron death resulting from necrotic and apoptotic insults
    • Lee AL, Dumas TC, Tarapore PE, et al. Potassium channel gene therapy can prevent neuron death resulting from necrotic and apoptotic insults. J Neurochem 2003; 86: 1079-88.
    • (2003) J Neurochem , vol.86 , pp. 1079-1088
    • Lee, A.L.1    Dumas, T.C.2    Tarapore, P.E.3
  • 33
    • 0037188928 scopus 로고    scopus 로고
    • Diversity in mitochondrial function explains differences in vascular oxygen sensing
    • Michelakis ED, Hampl V, Nsair A, et al. Diversity in mitochondrial function explains differences in vascular oxygen sensing. Circ Res 2002; 90: 1307-15.
    • (2002) Circ Res , vol.90 , pp. 1307-1315
    • Michelakis, E.D.1    Hampl, V.2    Nsair, A.3
  • 35
    • 0036733645 scopus 로고    scopus 로고
    • + channel, a regulator of tumor cell apoptosis and proliferation
    • + channel, a regulator of tumor cell apoptosis and proliferation. Cancer Res 2002; 62: 4843-48.
    • (2002) Cancer Res , vol.62 , pp. 4843-4848
    • Wang, H.1    Zhang, Y.2    Cao, L.3
  • 37
    • 11844297824 scopus 로고    scopus 로고
    • Protective effects of TASK-3 (KCNK9) and related 2P K channels during cellular stress
    • Liu C, Cotten JF, Schuyler JA, et al. Protective effects of TASK-3 (KCNK9) and related 2P K channels during cellular stress. Brain Res 2005; 1031: 164-73.
    • (2005) Brain Res , vol.1031 , pp. 164-173
    • Liu, C.1    Cotten, J.F.2    Schuyler, J.A.3
  • 38
    • 79955568493 scopus 로고    scopus 로고
    • Expression of TASK-2 and its upregulation by B cell receptor stimulation in WEHI-231 mouse immature B cells
    • Nam JH, Shin DH, Zheng H, et al. Expression of TASK-2 and its upregulation by B cell receptor stimulation in WEHI-231 mouse immature B cells. Am J Physiol Cell Physiol 2011; 300: C1013-22.
    • (2011) Am J Physiol Cell Physiol , vol.300 , pp. 1013-1022
    • Nam, J.H.1    Shin, D.H.2    Zheng, H.3
  • 39
    • 84857779494 scopus 로고    scopus 로고
    • Targeting ion channels in leukemias: A new challenge for treatment
    • Arcangeli A, Pillozzi S, Becchetti A. Targeting ion channels in leukemias: a new challenge for treatment. Curr Med Chem 2012; 19: 683-96.
    • (2012) Curr Med Chem , vol.19 , pp. 683-696
    • Arcangeli, A.1    Pillozzi, S.2    Becchetti, A.3
  • 40
    • 84857771935 scopus 로고    scopus 로고
    • Targeting the voltagedependent K(+) channels Kv1. 3 and Kv1. 5 as tumor biomarkers for cancer detection and prevention
    • Felipe A, Bielanska J, Comes N, et al. Targeting the voltagedependent K(+) channels Kv1. 3 and Kv1. 5 as tumor biomarkers for cancer detection and prevention. Curr Med Chem 2012; 19: 661-74.
    • (2012) Curr Med Chem , vol.19 , pp. 661-674
    • Felipe, A.1    Bielanska, J.2    Comes, N.3
  • 41
    • 79951681014 scopus 로고    scopus 로고
    • Singlepoint mutations of a lysine residue change function of Bax and BclxL expressed in Bax-and Bak-less mouse embryonic fibroblasts: Novel insights into the molecular mechanisms of Bax-induced apoptosis
    • Szabò I, Soddemann M, Leanza L, Zoratti M, Gulbins E. Singlepoint mutations of a lysine residue change function of Bax and BclxL expressed in Bax-and Bak-less mouse embryonic fibroblasts: novel insights into the molecular mechanisms of Bax-induced apoptosis. Cell Death Differ 2011; 18: 427-38.
    • (2011) Cell Death Differ , vol.18 , pp. 427-438
    • Szabò, I.1    Soddemann, M.2    Leanza, L.3    Zoratti, M.4    Gulbins, E.5
  • 42
    • 79953791880 scopus 로고    scopus 로고
    • Activation of the permeability transition pore by Bax via inhibition of the mitochondrial BK channel
    • Cheng Y, Gulbins E, Siemen D. Activation of the permeability transition pore by Bax via inhibition of the mitochondrial BK channel. Cell Physiol Biochem 2011; 27: 191-200.
    • (2011) Cell Physiol Biochem , vol.27 , pp. 191-200
    • Cheng, Y.1    Gulbins, E.2    Siemen, D.3
  • 43
    • 84870410761 scopus 로고    scopus 로고
    • Induction of apoptosis in macrophages via Kv1. 3 and Kv1. 5 potassium channels
    • Leanza L, Zoratti M, Gulbins E, Szabò I. Induction of apoptosis in macrophages via Kv1. 3 and Kv1. 5 potassium channels. Curr Med Chem 2012; 19: 5394-404.
    • (2012) Curr Med Chem , vol.19 , pp. 5394-5404
    • Leanza, L.1    Zoratti, M.2    Gulbins, E.3    Szabò, I.4
  • 44
    • 84862491784 scopus 로고    scopus 로고
    • General Sensitization of melanoma cells for TRAIL-induced apoptosis by the potassium channel inhibitor TRAM-34 depends on release of SMAC
    • Quast SA, Berger A, Buttstädt N, Friebel K, Schönherr R, Eberle J. General Sensitization of melanoma cells for TRAIL-induced apoptosis by the potassium channel inhibitor TRAM-34 depends on release of SMAC. PLoS One 2012; 7: e39290.
    • (2012) PLoS One , vol.7
    • Quast, S.A.1    Berger, A.2    Buttstädt, N.3    Friebel, K.4    Schönherr, R.5    Eberle, J.6
  • 45
    • 28744458859 scopus 로고    scopus 로고
    • Bioconductor: Open software development for computational biology and bioinformatics
    • Gentleman RC, Carey VJ, Bates DM, et al. Bioconductor: open software development for computational biology and bioinformatics. Genome Biol 2004; 5: R80.
    • (2004) Genome Biol , vol.5
    • Gentleman, R.C.1    Carey, V.J.2    Bates, D.M.3
  • 48
    • 84893004748 scopus 로고    scopus 로고
    • URL
    • Wright Ken. Corrgram package (2012). URL http://cran. rproject. org/web/packages/corrgram/index. html/.
    • (2012) Corrgram package
    • Ken, W.1
  • 50
    • 79959812980 scopus 로고    scopus 로고
    • Comparative analysis of proteome and transcriptome variation in mouse
    • Ghazalpour A, Bennett B, Petyuk VA, et al. Comparative analysis of proteome and transcriptome variation in mouse. PLoS Genet 2011; 7: e1001393.
    • (2011) PLoS Genet , vol.7
    • Ghazalpour, A.1    Bennett, B.2    Petyuk, V.A.3
  • 52
    • 33646816431 scopus 로고    scopus 로고
    • Potent antitumor activity of a novel cationic pyridinium-ceramide alone or in combination with gemcitabine against human head and neck squamous cell carcinomas in vitro and in vivo
    • Senkal CE, Ponnusamy S, Rossi MJ, et al. Potent antitumor activity of a novel cationic pyridinium-ceramide alone or in combination with gemcitabine against human head and neck squamous cell carcinomas in vitro and in vivo, J. Pharmacol. Exp. Ther 2006; 317: 1188-99.
    • (2006) J. Pharmacol. Exp Ther , vol.317 , pp. 1188-1199
    • Senkal, C.E.1    Ponnusamy, S.2    Rossi, M.J.3
  • 55
    • 73149088816 scopus 로고    scopus 로고
    • Functional and structural alterations in the endoplasmic reticulum and mitochondria during apoptosis triggered by C2-ceramide and CD95/APO-1/FAS receptor stimulation
    • Ferrari D, Pinton P, Campanella M, et al. Functional and structural alterations in the endoplasmic reticulum and mitochondria during apoptosis triggered by C2-ceramide and CD95/APO-1/FAS receptor stimulation. Biochem Biophys Res Commun 2010; 391: 575-81.
    • (2010) Biochem Biophys Res Commun , vol.391 , pp. 575-581
    • Ferrari, D.1    Pinton, P.2    Campanella, M.3
  • 56
    • 0030832241 scopus 로고    scopus 로고
    • Ceramide-induced inhibition of T lymphocyte voltage-gated potassium channel is mediated by tyrosine kinases
    • Gulbins E, Szabo I, Baltzer K, Lang F. Ceramide-induced inhibition of T lymphocyte voltage-gated potassium channel is mediated by tyrosine kinases. Proc Natl Acad Sci USA; 1997; 94: 7661-6.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 7661-7666
    • Gulbins, E.1    Szabo, I.2    Baltzer, K.3    Lang, F.4
  • 57
    • 0038581115 scopus 로고    scopus 로고
    • Ceramide inhibits the potassium channel Kv1. 3 by the formation of membrane platforms
    • Bock J, Szabó I, Gamper N, Adams C, Gulbins E. Ceramide inhibits the potassium channel Kv1. 3 by the formation of membrane platforms. Biochem Biophys Res Commun 2003; 305: 890-7.
    • (2003) Biochem Biophys Res Commun , vol.305 , pp. 890-897
    • Bock, J.1    Szabó, I.2    Gamper, N.3    Adams, C.4    Gulbins, E.5
  • 58
    • 8644263758 scopus 로고    scopus 로고
    • Ion channels and membrane rafts in apoptosis
    • Szabò I, Adams C, Gulbins E. Ion channels and membrane rafts in apoptosis. Pflugers Arch 2004; 448: 304-12.
    • (2004) Pflugers Arch , vol.448 , pp. 304-312
    • Szabò, I.1    Adams, C.2    Gulbins, E.3
  • 59
    • 29244467945 scopus 로고    scopus 로고
    • Downregulation of the HERG (KCNH2) K(+) channel by ceramide: Evidence for ubiquitin-mediated lysosomal degradation
    • Chapman H, Ramström C, Korhonen L, et al. Downregulation of the HERG (KCNH2) K(+) channel by ceramide: evidence for ubiquitin-mediated lysosomal degradation. J Cell Sci 2005; 118: 5325-34.
    • (2005) J Cell Sci , vol.118 , pp. 5325-5334
    • Chapman, H.1    Ramström, C.2    Korhonen, L.3
  • 61
    • 77953758600 scopus 로고    scopus 로고
    • Role of Kv1. 3 mitochondrial potassium channel in apoptotic signalling in lymphocytes
    • Gulbins E, Sassi N, Grassmè H, Zoratti M, Szabò I. Role of Kv1. 3 mitochondrial potassium channel in apoptotic signalling in lymphocytes. Biochim Biophys Acta 2010; 1797: 1251-9.
    • (2010) Biochim Biophys Acta , vol.1797 , pp. 1251-1259
    • Gulbins, E.1    Sassi, N.2    Grassmè, H.3    Zoratti, M.4    Szabò, I.5
  • 62
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh AA, Eisen MB, Davis RE, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 2000; 403: 503-11.
    • (2000) Nature , vol.403 , pp. 503-511
    • Alizadeh, A.A.1    Eisen, M.B.2    Davis, R.E.3
  • 63
    • 0038721967 scopus 로고    scopus 로고
    • Expression of voltage-gated potassium channels Kv 1. 3 and Kv 1. 5 in human gliomas
    • Preussat K, Beetz C, Schrey M, et al. Expression of voltage-gated potassium channels Kv 1. 3 and Kv 1. 5 in human gliomas. Neurosci Lett 2003; 346: 33-6.
    • (2003) Neurosci Lett , vol.346 , pp. 33-36
    • Preussat, K.1    Beetz, C.2    Schrey, M.3
  • 64
    • 34447130413 scopus 로고    scopus 로고
    • Reduced Kv 1. 3 potassium channel expression in human prostate cancer
    • Abdul M, Hoosein N. Reduced Kv 1. 3 potassium channel expression in human prostate cancer. J Membr Biol 2006; 214: 99-102.
    • (2006) J Membr Biol , vol.214 , pp. 99-102
    • Abdul, M.1    Hoosein, N.2
  • 65
  • 66
    • 0042530130 scopus 로고    scopus 로고
    • Activity of potassium channel blockers in breast cancer
    • Abdul M, Santo A, Hoosein N. Activity of potassium channel blockers in breast cancer. Anticancer Res 2003; 23: 3347-51.
    • (2003) Anticancer Res , vol.23 , pp. 3347-3351
    • Abdul, M.1    Santo, A.2    Hoosein, N.3
  • 67
    • 70349564255 scopus 로고    scopus 로고
    • + channel subunit as potential diagnostic marker and therapeutic target for breast cancer
    • + channel subunit as potential diagnostic marker and therapeutic target for breast cancer. BMB Reports 2009; 42: 535-39.
    • (2009) BMB Reports , vol.42 , pp. 535-539
    • Jang, S.H.1    Kang, K.S.2    Ryu, P.D.3    Lee, S.Y.4
  • 68
    • 0036725867 scopus 로고    scopus 로고
    • Voltage-gated potassium ion channels in colon cancer
    • Abdul M, Hoosein N. Voltage-gated potassium ion channels in colon cancer. Oncol Rep 2002; 9: 961-4.
    • (2002) Oncol Rep , vol.9 , pp. 961-964
    • Abdul, M.1    Hoosein, N.2
  • 70
    • 68949088285 scopus 로고    scopus 로고
    • Deregulation of 2 potassium channels in pancreas adenocarcinomas: Implication of KV1. 3 gene promoter methylation
    • Brevet M, Fucks D, Chatelain D, et al. Deregulation of 2 potassium channels in pancreas adenocarcinomas: implication of KV1. 3 gene promoter methylation. Pancreas 2009; 38: 649-54.
    • (2009) Pancreas , vol.38 , pp. 649-654
    • Brevet, M.1    Fucks, D.2    Chatelain, D.3
  • 71
    • 84861961282 scopus 로고    scopus 로고
    • +) channel Kv1. 3 and Kv1. 5 expression correlates with leiomyosarcoma aggressiveness
    • +) channel Kv1. 3 and Kv1. 5 expression correlates with leiomyosarcoma aggressiveness. Oncol Lett 2012; 4: 227-30.
    • (2012) Oncol Lett , vol.4 , pp. 227-230
    • Bielanska, J.1    Hernández-Losa, J.2    Moline, T.3
  • 72
    • 79952098596 scopus 로고    scopus 로고
    • Dendrotoxin-suppresses tumor growth induced by human lung adenocarcinoma A549 cells in nude mice
    • Jang SH, Ryu PD, Lee SY. Dendrotoxin-suppresses tumor growth induced by human lung adenocarcinoma A549 cells in nude mice. J Vet Sci 2011; 12: 35-40.
    • (2011) J Vet Sci , vol.12 , pp. 35-40
    • Jang, S.H.1    Ryu, P.D.2    Lee, S.Y.3
  • 74
    • 33847389726 scopus 로고    scopus 로고
    • Expression of voltage-gated potassium channels in human and mouse colonic carcinoma
    • Ousingsawat J, Spitzner M, Puntheeranurak S, et al. Expression of voltage-gated potassium channels in human and mouse colonic carcinoma. Clin Cancer Res 2007; 13: 824-31.
    • (2007) Clin Cancer Res , vol.13 , pp. 824-831
    • Ousingsawat, J.1    Spitzner, M.2    Puntheeranurak, S.3
  • 76
    • 0036738165 scopus 로고    scopus 로고
    • HERG potassium channels are constitutively expressed in primary human acute myeloid leukemias and regulate cell proliferation of normal and leukemic hemopoietic progenitors
    • Pillozzi S, Brizzi MF, Balzi M, et al. HERG potassium channels are constitutively expressed in primary human acute myeloid leukemias and regulate cell proliferation of normal and leukemic hemopoietic progenitors. Leukemia 2002; 16: 1791-98.
    • (2002) Leukemia , vol.16 , pp. 1791-1798
    • Pillozzi, S.1    Brizzi, M.F.2    Balzi, M.3
  • 78
    • 67349213575 scopus 로고    scopus 로고
    • + channels and SDF-1 in acute leukemic cell migration
    • + channels and SDF-1 in acute leukemic cell migration. Exp Cell Res 2009; 315: 2256-64.
    • (2009) Exp Cell Res , vol.315 , pp. 2256-2264
    • Li, H.1    Du, Y.M.2    Guo, L.3
  • 81
    • 38349046725 scopus 로고    scopus 로고
    • + channel expression in human breast cancer cells: Involvement in cell cycle regulation and carcinogenesis
    • + channel expression in human breast cancer cells: involvement in cell cycle regulation and carcinogenesis. J Membr Biol 2008; 221: 1-6.
    • (2008) J Membr Biol , vol.221 , pp. 1-6
    • Ouadid-Ahidouch, H.1    Ahidouch, A.2
  • 83
    • 84865412158 scopus 로고    scopus 로고
    • Human ether à-gogo K(+) channel 1 (hEag1) regulates MDA-MB-231 breast cancer cell migration through Orai1-dependent calcium entry
    • Hammadi M, Chopin V, Matifat F, et al. Human ether à-gogo K(+) channel 1 (hEag1) regulates MDA-MB-231 breast cancer cell migration through Orai1-dependent calcium entry. J Cell Physiol 2012; 227: 3837-46.
    • (2012) J Cell Physiol , vol.227 , pp. 3837-3846
    • Hammadi, M.1    Chopin, V.2    Matifat, F.3
  • 84
    • 0033612265 scopus 로고    scopus 로고
    • 2+ influx in carcinoma cells of colon cancer
    • 2+ influx in carcinoma cells of colon cancer. Life Sci 1999; 65: 55-62.
    • (1999) Life Sci , vol.65 , pp. 55-62
    • Yao, X.1    Kwan, H.Y.2
  • 85
    • 9144274941 scopus 로고    scopus 로고
    • herg1 gene and HERG1 protein are overexpressed in colorectal cancers and regulate cell invasion of tumor cells
    • Lastraioli E, Guasti L, Crociani O, et al. herg1 gene and HERG1 protein are overexpressed in colorectal cancers and regulate cell invasion of tumor cells. Cancer Res 2004; 64: 606-11.
    • (2004) Cancer Res , vol.64 , pp. 606-611
    • Lastraioli, E.1    Guasti, L.2    Crociani, O.3
  • 86
    • 21244476712 scopus 로고    scopus 로고
    • + channel expression-related chemosensitivity in cancer cells and its modulation by erythromycin
    • + channel expression-related chemosensitivity in cancer cells and its modulation by erythromycin. Cancer Chemother Pharmacol 2005; 56: 212-20.
    • (2005) Cancer Chemother Pharmacol , vol.56 , pp. 212-220
    • Chen, S.Z.1    Jiang, M.2    Zhen, Y.S.3
  • 87
    • 34249879293 scopus 로고    scopus 로고
    • Cell shrinkage and monovalent cation fluxes: Role in apoptosis
    • Bortner CD, Cidlowski JA. Cell shrinkage and monovalent cation fluxes: role in apoptosis. Arch Biochem Biophys 2007; 462: 176-88.
    • (2007) Arch Biochem Biophys , vol.462 , pp. 176-188
    • Bortner, C.D.1    Cidlowski, J.A.2
  • 88
    • 0042829363 scopus 로고    scopus 로고
    • Regulation and critical role of potassium homeostasis in apoptosis
    • Yu SP. Regulation and critical role of potassium homeostasis in apoptosis. Prog Neurobiol 2003; 70: 363-86.
    • (2003) Prog Neurobiol , vol.70 , pp. 363-386
    • Yu, S.P.1
  • 89
    • 0033776392 scopus 로고    scopus 로고
    • Effects of tetraethylammonium analogs on apoptosis and membrane currents in cultured cortical neurons. J Pharmacol. Exp
    • Wang X, Xiao AY, Ichinose T, Yu SP. Effects of tetraethylammonium analogs on apoptosis and membrane currents in cultured cortical neurons. J Pharmacol. Exp. Ther 2000; 295: 524-30.
    • (2000) Ther , vol.295 , pp. 524-530
    • Wang, X.1    Xiao, A.Y.2    Ichinose, T.3    Yu, S.P.4
  • 90
    • 0038304416 scopus 로고    scopus 로고
    • Potassium channel blockers attenuate hypoxia-and ischemiainduced neuronal death in vitro and in vivo
    • (2003)
    • Wei L, Yu SP, Gottron F, Snider BJ, Zipfel GJ, Choi DW. (2003). Potassium channel blockers attenuate hypoxia-and ischemiainduced neuronal death in vitro and in vivo. Stroke 2003; 34: 1281-6.
    • (2003) Stroke , vol.34 , pp. 1281-1286
    • Wei, L.1    Yu, S.P.2    Gottron, F.3    Snider, B.J.4    Zipfel, G.J.5    Choi, D.W.6
  • 91
    • 0000521423 scopus 로고    scopus 로고
    • Mediation of neuronal apoptosis by enhancement of outward potassium current
    • Yu SP, Yeh CH, Sensi SL, et al. Mediation of neuronal apoptosis by enhancement of outward potassium current. Science 1997; 278: 114-7.
    • (1997) Science , vol.278 , pp. 114-117
    • Yu, S.P.1    Yeh, C.H.2    Sensi, S.L.3
  • 92
    • 84881479922 scopus 로고    scopus 로고
    • Clofazimine, Psora-4 and PAP-1, inhibitors of the potassium channel Kv1. 3, as a new and selective therapeutic strategy in chronic lymphocytic leukemia
    • Leanza L, Trentin L, Becker KA, Frezzato F, Zoratti M, Gulbins E, Szabò I. Clofazimine, Psora-4 and PAP-1, inhibitors of the potassium channel Kv1. 3, as a new and selective therapeutic strategy in chronic lymphocytic leukemia. Leukemia 2013; 27: 1782-1785.
    • (2013) Leukemia , vol.27 , pp. 1782-1785
    • Leanza, L.1    Trentin, L.2    Becker, K.A.3    Frezzato, F.4    Zoratti, M.5    Gulbins, E.6    Szabò, I.7
  • 93
    • 2442660257 scopus 로고    scopus 로고
    • Kv1. 3-blocking 5-phenylalkoxypsoralens: A new class of immunomodulators
    • Vennekamp J, Wulff H, Beeton C, et al. Kv1. 3-blocking 5-phenylalkoxypsoralens: a new class of immunomodulators. Mol Pharmacol 2004; 65: 1364-74.
    • (2004) Mol Pharmacol , vol.65 , pp. 1364-1374
    • Vennekamp, J.1    Wulff, H.2    Beeton, C.3
  • 94
    • 27544454783 scopus 로고    scopus 로고
    • Design of PAP-1, a selective small molecule Kv1. 3 blocker, for the suppression of effector memory T cells in autoimmune diseases
    • Schmitz A, Sankaranarayanan A, Azam P, et al. Design of PAP-1, a selective small molecule Kv1. 3 blocker, for the suppression of effector memory T cells in autoimmune diseases. Mol Pharmacol 2005; 68: 1254-70.
    • (2005) Mol Pharmacol , vol.68 , pp. 1254-1270
    • Schmitz, A.1    Sankaranarayanan, A.2    Azam, P.3
  • 95
    • 58049211941 scopus 로고    scopus 로고
    • Clofazimine inhibits human Kv1. 3 potassium channel by perturbing calcium oscillation in T lymphocytes
    • Ren YR, Pan F, Parvez S, et al. Clofazimine inhibits human Kv1. 3 potassium channel by perturbing calcium oscillation in T lymphocytes. PLoS One 2008; 3: e4009.
    • (2008) PLoS One , vol.3
    • Ren, Y.R.1    Pan, F.2    Parvez, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.