Expression of K+ channels in normal and cancerous human breast

Histology and Histopathology

Volumn 23, Issue 8, 2008, Pages 965-972

  Brevet, Marie ^a,b   Ahidouch, Ahmed ^a,c   Sevestre, Henri ^b   Mervie, Philippe ^d   El Hiani, Yassine ^a   Robbe, Micheline ^e   Ouadid Ahidouch, Halima ^a  

^a UNIVERSITÉ DE PICARDIE JULES VERNE   (France)

^b Service d'Anatomie Pathologique   (France)

^c FACULTÉ DES SCIENCES   (Morocco)

^d Centre de Gynécologie Obstétrique   (France)

^e Service de Chirurgie Plastique   (France)

Author keywords

Breast tissue; Cancer; Human; Immunostaining; Potassium channels

Indexed keywords

CALCIUM ACTIVATED POTASSIUM CHANNEL; G PROTEIN COUPLED INWARDLY RECTIFYING POTASSIUM CHANNEL; POTASSIUM CHANNEL; PROTEIN BCL 2; TUMOR MARKER; VOLTAGE GATED POTASSIUM CHANNEL;

ADULT; AGED; ARTICLE; BREAST TUMOR; CANCER STAGING; CELL COUNT; ENZYME IMMUNOASSAY; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE; HUMAN; METABOLISM; METASTASIS; MIDDLE AGED; PAGET NIPPLE DISEASE; PATHOLOGY;

ADULT; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CARCINOMA, DUCTAL, BREAST; CELL COUNT; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, DIRECT; G PROTEIN-COUPLED INWARDLY-RECTIFYING POTASSIUM CHANNELS; HUMANS; IMMUNOENZYME TECHNIQUES; MIDDLE AGED; NEOPLASM STAGING; POTASSIUM CHANNELS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTO-ONCOGENE PROTEINS C-BCL-2; TUMOR MARKERS, BIOLOGICAL;

EID: 46249083887     PISSN: 02133911     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Abdul M. and Hoosein N. (2002). Expression and activity of potassium ion channels in human prostate cancer. Cancer lett. 186, 99-105.
2. Abdul M. and Hoosein N. (2006). Reduced KV1.3 Potassium channel expression in human prostate cancer. J. Membr. Biol. 214, 99-102.
3. Abdul M., Santo A. and Hoosein N. (2003). Activity of potassium channel-blockers in breast cancer. Anticancer Res. 23, 3347-3351.
4. Ahlin C., Aaltonen K., Amini R.M., Nevanlinna H., Fjallskog M.L. and Blomqvist C. (2007). Ki67 and cyclin A as prognostic factors in early breast cancer. What are the optimal cut-off values? Histopathology 51, 491-498.
5. Bock J., Szabo I., Jekle A. and Gulbins E. (2002). Actinomycin Dinduced apoptosis involves the potassium channel KV1.3. Biochem. Biophys. Res. Commun. 295, 526-531.
6. Brevnova E.E., Platoshyn O., Zhang S. and Yuan J.X. (2004). Overexpression of human KCNA5 increases IK V and enhances apoptosis. Am. J. Physiol. Cell. Physiol. 287, C715-C722.
7. Bringmann A., Francke M., Pannicke T., Biedermann B., Kodal H., Faude F., Reichelt W. and Reichenbach A. (2000). Role of glial K(+) channels in ontogeny and gliosis: a hypothesis based upon studies on Muller cells. Glia 29, 35-44
8. Chen S.Z., Jiang M. and Zhen Y.S. (2005). HERG K+ channel expression-related chemosensitivity in cancer cells and its modulation by erythromycin. Cancer Chem. Pharmacol. 56, 212-220.
9. Coiret G., Matifat F., Hague F. and Ouadid-Ahidouch H. (2005). 17- beta-estradiol activates maxi-K channels through a non-genomic pathway in human breast cancer cells. FEBS Lett. 579, 2995-3000
10. Conti M. (2004). Targeting K+ channels for cancer therapy. J. Exp. Ther. Oncol 4, 161-166.
11. Ekhterae D., Platoshyn O., Krick S., Yu Y., McDaniel S.S. and Yuan J.X. (2001). Bcl-2 decreases voltage-gated K+ channel activity and enhances survival in vascular smooth muscle cells. Am. J. Physiol. Cell. Physiol. 281, C157-C165.
12. Fraser S.P., Grimes J.A., Diss J.K., Stewart D., Dolly J.O. and Djamgoz M.B. (2003). Predominant expression of KV1.3 voltage-gated K+ channel subunit in rat prostate cancer cell lines: electrophysiological, pharmacological and molecular characterisation. Pflugers Arch. 446, 559-571.
13. Hemmerlein B., Weseloh R.M., Mello de Queiroz F., Knotgen H., Sanchez A., Rubio M.E., Martin S., Schliephacke T., Jenke M., Heinz-Joachim-Radzun, Stuhmer W. and Pardo L.A. (2006). Overexpression of Eag1 potassium channels in clinical tumours. Mol. Cancer 5, 41.
14. Laniado M.E., Fraser S.P. and Djamgoz M.B. (2001). Voltage-gated K+ channel activity in human prostate cancer cell lines of markedly different metastatic potential: distinguishing characteristics of PC-3 and LNCaP cells. Prostate 46, 262-274.
15. Mu D., Chen L., Zhang X., See L.H., Koch C.M., Yen C., Tong J.J., Spiegel L., Nguyen K.C., Servoss A., Peng Y., Pei L., Marks J.R., Lowe S., Hoey T., Jan L.Y., McCombie W.R., Wigler M.H. and Powers S. (2003). Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. Cancer Cell 3, 297-302
16. Nerbonne J.M. and Kass R.S. (2005). Molecular physiology of cardiac repolarization. Physiol. Rev. 85, 1205-1253.
17. O'Grady S.M. and Lee S.Y. (2005). Molecular diversity and function of voltage-gated (KV) potassium channels in epithelial cells. Int. J. Biochem. Cell Biol. 37, 1578-1594
18. Ouadid-Ahidouch H., Chaussade F., Roudbaraki M., Slomianny C., Dewailly E., Delcourt P. and Prevarskaya N. (2000). KV1.1 K+ channels identification in human breast carcinoma cells: involvement in cell proliferation. Biochem. Biophys. Research Commun. 278, 272-277.
19. Ouadid-Ahidouch H., LeBourhis X., Roudbaraki M., Toillon R.A., Delcourt P. and Prevaskaya N. (2001). Changes in the K+ currentdensity of MCF-7 cells during progression through the cell cycle: possible involvement of an h-ether.a-gogo K+ channel. Receptors Channels 7, 345-356.
20. Ouadid-Ahidouch H, Roudbaraki M, Ahidouch A, Delcourt P and Prevarskaya N (2004a). Cell-cycle-dependent expression of the large Ca2+-activated K+ channels in breast cancer cells. Biochem. Biophys. Res. Commun. 316, 244-251.
21. Ouadid-Ahidouch H., Roudbaraki M., Ahidouch A., Delcourt P. and Prevarskaya N. (2004b). Functional and molecular identification of intermediate-conductance Ca2+-activated K+ channels in breast cancer cells: association with cell cycle progression. Am. J. Physiol. Cell Physiol. 287, C125-C134.
22. Pardo L.A., Del Camino D., Sanchez A., Alves F., Bruggemann A., Beckh S. and Stuhmer W. (1999). Oncogenic potential of EAG K+ channels. EMBO J. 18, 5540-5547.
23. Shieh C., Coghlan M., Sullivan J.P. and Gopalakrishnan M. (2000). Potassium channels: molecular defects, diseases, and therapeutic opportunities. Pharmacol. Res. 52, 557-594.
24. Stringer B.K., Cooper A.G. and Shepard S.B. (2001). Overexpression of the G-protein inwardly rectifying potassium channel 1 (GIRK1) in primary breast carcinomas correlates with axillary lymph node metastasis. Cancer Res. 61, 582-588.
25. Vincent G.M. and Zhang L. (2005). The role of genotyping in diagnosing cardiac channelopathies: progress to date. Mol. Diagn. 9, 105-118
26. Wang Z. (2004). Roles of K+ channels in regulating tumour cell proliferation and apoptosis. Pflugers Arch. 448, 274-286.
27. Wang H., Zhang Y., Cao L., Han H., Wang J., Yang B., Nattel S. and Wang Z. (2002). HERG K+ channel, a regulator of tumor cell apoptosis and proliferation. Cancer Res. 62, 4843-4848.
28. Wonderlin W.F. and Strobl J.S. (1996). Potassium channels, proliferation and G1 progression. J. Membr. Biol. 154, 91-107.
29. Yarden Y. and Sliwkowski M.X. (2001). Untangling the ErbB signaling network. Nat. Rev. Mol. Cell Biol. 2, 127-137.
30. Yu S.P. (2003). Regulation and critical role of potassium homeostasis in apoptosis. Prog. Neurobiol. 70, 363-386.
31. Yu S.P. and Choi D.W. (2000). Ions, cell volume, and apoptosis. Proc. Natl. Acad. Sci. USA 97, 9360-9362.