KCNE4 suppresses Kv1.3 currents by modulating trafficking, surface expression and channel gating

Journal of Cell Science

Volumn 122, Issue 20, 2009, Pages 3738-3748

  Solé, Laura ^a   Roura Ferrer, Meritxell ^a,c   Pérez Verdaguer, Mireia ^a   Oliveras, Anna ^a   Calvo, Maria ^a   Fernández Fernández, José Manuel ^b   Felipe, Antonio ^a  

^a UNIVERSITY OF BARCELONA   (Spain)

^b UNIVERSITAT POMPEU FABRA   (Spain)

^c UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Channelosome; KCNE regulatory subunits; Kv1.3; Leukocytes; Surface expression; Trafficking

Indexed keywords

DEXAMETHASONE; LIPOPOLYSACCHARIDE; MESSENGER RNA; POTASSIUM CHANNEL KCNE2; POTASSIUM CHANNEL KCNE4; POTASSIUM CHANNEL KV1.3; POTASSIUM ION; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CELL MEMBRANE; CELL SURFACE; CELLULAR DISTRIBUTION; CHANNEL GATING; CONTROLLED STUDY; ENDOPLASMIC RETICULUM; HUMAN; HUMAN CELL; IMMUNOMODULATION; LEUKOCYTE; LIPID RAFT; MACROPHAGE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; POTASSIUM CURRENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING;

ANIMALS; CELL MEMBRANE; ENDOPLASMIC RETICULUM; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GENE EXPRESSION REGULATION; HUMANS; ION CHANNEL GATING; KV1.3 POTASSIUM CHANNEL; MACROPHAGES; MICE; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN BINDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN TRANSPORT; RATS; RNA, MESSENGER;

EID: 70350366606     PISSN: 00219533     EISSN: None     Source Type: Journal    
DOI: 10.1242/jcs.056689     Document Type: Article

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