Differential role of IK and BK potassium channels as mediators of intrinsic and extrinsic apoptotic cell death

American Journal of Physiology - Cell Physiology

Volumn 303, Issue 10, 2012, Pages

  McFerrin, Michael B ^a   Turner, Kathryn L ^a   Cuddapah, Vishnu Anand ^a   Sontheimer, Harald ^a  

^a University of Alabama at Birmingham   (United States)

Author keywords

Apoptosis; Apoptotic volume decrease; AVD; Calciumactivated potassium channels; Cell volume

Indexed keywords

CALCIUM; CASPASE 3; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; FURA 2; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; LARGE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; STAUROSPORINE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

APOPTOSIS; ARTICLE; CALCIUM METABOLISM; CANCER CELL CULTURE; CANCER GRADING; CELL DEATH; CELL VOLUME; CELLULAR PARAMETERS; CONTROLLED STUDY; ENZYME ACTIVATION; GLIOBLASTOMA; GLIOMA CELL; HUMAN; HUMAN CELL; PRIORITY JOURNAL; TUMOR CELL LINE;

APOPTOSIS; CALCIUM; CELL LINE, TUMOR; CLOTRIMAZOLE; ENZYME INHIBITORS; GENE EXPRESSION REGULATION; GLIOMA; HUMANS; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; ION CHANNEL GATING; LARGE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; STAUROSPORINE; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 84869210513     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00040.2012     Document Type: Article

References (45)

1. Abdullaev IF, Rudkouskaya A, Mongin AA, Kuo YH. Calcium-activated potassium channels BK and IK1 are functionally expressed in human gliomas but do not regulate cell proliferation. PLos One 5: e12304, 2010
2. + signaling. Science 314: 615-620, 2006.
3. Bertrand R, Solary E, O'Connor P, Kohn KW, Pommier Y. Induction of a common pathway of apoptosis by staurosporine. Exp Cell Res 211: 314-321, 1994.
4. Bomben VC, Sontheimer H. Disruption of Transient Receptor Potential Canonical Channel 1 causes incomplete cytokinesis and slows the growth of human malignant gliomas. Glia 58: 1145-1156, 2010.
5. Bomben VC, Turner KL, Barclay TT, Sontheimer H. Transient receptor potential canonical channels are essential for chemotactic migration of human malignant gliomas. J Cell Physiol 226: 1879-1888, 2011.
6. + efflux in the activation of apoptosis. J Biol Chem 272: 32436-32442, 1997
7. Denault JB, Salvesen GS. Caspases: keys in the ignition of cell death. Chem Rev 102: 4489-4500, 2002.
8. Eid T, Williamson A, Lee TS, Petroff OA, de Lanerolle NC. Glutamate and astrocytes-key players in human mesial temporal lobe epilepsy? Epilepsia 49, Suppl 2: 42-52, 2008.
9. + channel activity and enhances survival in vascular smooth muscle cells. Am J Physiol Cell Physiol 281: C157-C165, 2001.
10. Elliott JI, Higgins CF. IKCa1 activity is required for cell shrinkage, phosphatidylserine translocation and death in T lymphocyte apoptosis. EMBO Rep 4: 189-194, 2003.
11. Ernest NJ, Habela CW, Sontheimer H. Cytoplasmic condensation is both necessary and sufficient to induce apoptotic cell death. J Cell Sci 121: 3-7, 2008.
12. Ernest NJ, Weaver AK, Van Duyn LB, Sontheimer HW. Relative contribution of chloride channels and transporters to regulatory volume decrease in human glioma cells. Am J Physiol Cell Physiol 288: C1451-C1460, 2005.
13. + channel in glioblastoma GL-15 cells. Cell Physiol Biochem 18: 47-56, 2006.
14. + channel for the short-term survival of injured erythrocytes. Pflügers Arch 460: 1029-1044, 2010.
15. Green DR, Reed JC. Mitochondria and apoptosis. Science 281: 1309-1312, 1998.
16. Haanen C, Vermes I. Apoptosis and inflammation. Mediators Inflamm 4: 5-15, 1995.
17. Hamill OP, Marty A, Neher E, Sakmann B, Sigworth FJ. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch 391: 85-100, 1981.
18. Ishii TM, Silvia C, Hirschberg B, Bond CT, Adelman JP, Maylie J. A human intermediate conductance calcium-activated potassium channel. Proc Natl Acad Sci USA 94: 11651-11656, 1997.
19. + channels induces apoptosis in vascular smooth muscle cells. Am J Physiol Cell Physiol 280: C970-C979, 2001.
20. + channels in pulmonary vascular smooth muscle cells. Am J Physiol Heart Circ Physiol 282: H184-H193, 2002.
21. + channels in human erythrocyte apoptosis. Am J Physiol Cell Physiol 285: C1553-C1560, 2003.
22. Li P, Nijhawan D, Budihardjo I, Srinivasula SM, Ahmad M, Alnemri ES, Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/ caspase-9 complex initiates an apoptotic protease cascade. Cell 91: 479-489, 1997.
23. Liu X, Chang Y, Reinhart PH, Sontheimer H, Chang Y. Cloning and characterization of glioma BK, a novel BK channel isoform highly expressed in human glioma cells. J Neurosci 22: 1840-1849, 2002.
24. Liu X, Kim CN, Yang J, Jemmerson R, Wang X. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c. Cell 86: 147-157, 1996.
25. Maeno E, Ishizaki Y, Kanaseki T, Hazama A, Okada Y. Normotonic cell shrinkage because of disordered volume regulation is an early prerequisite to apoptosis. Proc Natl Acad Sci USA 97: 9487-9492, 2000.
26. Mattson MP, Chan SL. Calcium orchestrates apoptosis. Nat Cell Biol 5: 1041-1043, 2003.
27. Meier P, Finch A, Evan G. Apoptosis in development. Nature 407: 796-801, 2000.
28. Mercille S, Massie B. Induction of apoptosis in nutrient-deprived cultures of hybridoma and myeloma cells. Biotechnol Bioeng 44: 1140-1154, 1994
29. Okada Y, Shimizu T, Maeno E, Tanabe S, Wang X, Takahashi N. Volume-sensitive chloride channels involved in apoptotic volume decrease and cell death. J Membr Biol 209: 21-29, 2006.
30. Pal S, Hartnett KA, Nerbonne JM, Levitan ES, Aizenman E. Mediation of neuronal apoptosis by Kv2.1-encoded potassium channels. J Neurosci 23: 4798-4802, 2003.
31. Ransom CB, Sontheimer H. BK channels in human glioma cells. J Neurophysiol 85: 790-803, 2001.
32. Rathmell JC, Thompson CB. Pathways of apoptosis in lymphocyte development, homeostasis, and disease. Cell 109, Suppl: S97-107, 2002.
33. Roos WP, Kaina B. DNA damage-induced cell death by apoptosis. Trends Mol Med 12: 440-450, 2006.
34. Slater AF, Stefan C, Nobel I, van den Dobbelsteen DJ, Orrenius S. Signalling mechanisms and oxidative stress in apoptosis. Toxicol Lett 82-83: 149-153, 1995.
35. Slee EA, Harte MT, Kluck RM, Wolf BB, Casiano CA, Newmeyer DD, Wang HG, Reed JC, Nicholson DW, Alnemri ES, Green DR, Martin SJ. Ordering the cytochrome c-initiated caspase cascade: hierarchical activation of caspases-2,-3,-6,-7,-8, and-10 in a caspase-9-dependent manner. J Cell Biol 144: 281-292, 1999.
36. Thorburn A. Death receptor-induced cell killing. Cell Signal 16: 139-144, 2004.
37. Van Cruchten S, Van Den BW. Morphological and biochemical aspects of apoptosis, oncosis and necrosis. Anat Histol Embryol 31: 214-223, 2002
38. Vergara C, Latorre R, Marrion NV, Adelman JP. Calcium-activated potassium channels. Curr Opin Neurobiol 8: 321-329, 1998.
39. Weaver AK, Bomben VC, Sontheimer H. Expression and function of calcium-activated potassium channels in human glioma cells. Glia 54: 223-233, 2006.
40. 2+]1 to ion channel activation. J Biol Chem 282: 31568, 2007.
41. Wei L, Xiao AY, Jin C, Yang A, Lu ZY, Yu SP. Effects of chloride and potassium channel blockers on apoptotic cell shrinkage and apoptosis in cortical neurons. Pflügers Arch 448: 325-334, 2004.
42. + channel, IKCa1: a potential immunosuppressant. Proc Natl Acad Sci USA 97: 8151-8156, 2000.
43. Yan J, Aldrich RW. LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium. Nature 466: 513-516, 2010
44. Yu SP, Yeh CH, Sensi SL, Gwag BJ, Canzoniero LM, Farhangrazi ZS, Ying HS, Tian M, Dugan LL, Choi DW. Mediation of neuronal apoptosis by enhancement of outward potassium current. Science 278: 114-117, 1997.
45. + channel inhibitor identified by high-throughput screening in yeast. Mol Pharmacol 65: 214-219, 2004.