-
1
-
-
0027373764
-
-
M. C. Raff et al., Science 262, 695 (1993); C. B. Thompson, ibid. 267, 1456 (1995); D. W. Choi, Curr. Opin. Neurobiol. 6, 667 (1996).
-
(1993)
Science
, vol.262
, pp. 695
-
-
Raff, M.C.1
-
2
-
-
0028943734
-
-
M. C. Raff et al., Science 262, 695 (1993); C. B. Thompson, ibid. 267, 1456 (1995); D. W. Choi, Curr. Opin. Neurobiol. 6, 667 (1996).
-
(1995)
Science
, vol.267
, pp. 1456
-
-
Thompson, C.B.1
-
3
-
-
0030273118
-
-
M. C. Raff et al., Science 262, 695 (1993); C. B. Thompson, ibid. 267, 1456 (1995); D. W. Choi, Curr. Opin. Neurobiol. 6, 667 (1996).
-
(1996)
Curr. Opin. Neurobiol.
, vol.6
, pp. 667
-
-
Choi, D.W.1
-
4
-
-
0014767671
-
-
B. S. Scott and K. C. Fisher, Exp. Neurol. 27, 16 (1970); M. R. Bennett and W. White, Brain Res. 173, 549 (1979); A. Chalazonitis and G. D. Fischbach, Dev. Biol. 78, 173 (1980); F. Collins, M. F. Schmidt, P. B. Guthrie, S. B. Kater, J. Neurosci. 11, 2582 (1991).
-
(1970)
Exp. Neurol.
, vol.27
, pp. 16
-
-
Scott, B.S.1
Fisher, K.C.2
-
5
-
-
0018398854
-
-
B. S. Scott and K. C. Fisher, Exp. Neurol. 27, 16 (1970); M. R. Bennett and W. White, Brain Res. 173, 549 (1979); A. Chalazonitis and G. D. Fischbach, Dev. Biol. 78, 173 (1980); F. Collins, M. F. Schmidt, P. B. Guthrie, S. B. Kater, J. Neurosci. 11, 2582 (1991).
-
(1979)
Brain Res.
, vol.173
, pp. 549
-
-
Bennett, M.R.1
White, W.2
-
6
-
-
0019303611
-
-
B. S. Scott and K. C. Fisher, Exp. Neurol. 27, 16 (1970); M. R. Bennett and W. White, Brain Res. 173, 549 (1979); A. Chalazonitis and G. D. Fischbach, Dev. Biol. 78, 173 (1980); F. Collins, M. F. Schmidt, P. B. Guthrie, S. B. Kater, J. Neurosci. 11, 2582 (1991).
-
(1980)
Dev. Biol.
, vol.78
, pp. 173
-
-
Chalazonitis, A.1
Fischbach, G.D.2
-
7
-
-
0025936606
-
-
B. S. Scott and K. C. Fisher, Exp. Neurol. 27, 16 (1970); M. R. Bennett and W. White, Brain Res. 173, 549 (1979); A. Chalazonitis and G. D. Fischbach, Dev. Biol. 78, 173 (1980); F. Collins, M. F. Schmidt, P. B. Guthrie, S. B. Kater, J. Neurosci. 11, 2582 (1991).
-
(1991)
J. Neurosci.
, vol.11
, pp. 2582
-
-
Collins, F.1
Schmidt, M.F.2
Guthrie, P.B.3
Kater, S.B.4
-
8
-
-
0023244774
-
-
V. Gallo, A. Kingsbury, R. Balázs, O. S. Jorgensen, J. Neurosci. 7, 2203 (1987); J. L. Franklin and E. M. Johnson Jr., Trends Neurosci. 15, 501 (1992); Y. Enokido and H. Hatanaka, Neuroscience 57, 965 (1993); J-Y. Koh et al., Exp. Neurol. 135, 153 (1995); A. de Luca, M. Weller, A. Fontana, J. Neurosci. 16, 4174 (1996).
-
(1987)
J. Neurosci.
, vol.7
, pp. 2203
-
-
Gallo, V.1
Kingsbury, A.2
Balázs, R.3
Jorgensen, O.S.4
-
9
-
-
0026482631
-
-
V. Gallo, A. Kingsbury, R. Balázs, O. S. Jorgensen, J. Neurosci. 7, 2203 (1987); J. L. Franklin and E. M. Johnson Jr., Trends Neurosci. 15, 501 (1992); Y. Enokido and H. Hatanaka, Neuroscience 57, 965 (1993); J-Y. Koh et al., Exp. Neurol. 135, 153 (1995); A. de Luca, M. Weller, A. Fontana, J. Neurosci. 16, 4174 (1996).
-
(1992)
Trends Neurosci.
, vol.15
, pp. 501
-
-
Franklin, J.L.1
Johnson Jr., E.M.2
-
10
-
-
0027437533
-
-
V. Gallo, A. Kingsbury, R. Balázs, O. S. Jorgensen, J. Neurosci. 7, 2203 (1987); J. L. Franklin and E. M. Johnson Jr., Trends Neurosci. 15, 501 (1992); Y. Enokido and H. Hatanaka, Neuroscience 57, 965 (1993); J-Y. Koh et al., Exp. Neurol. 135, 153 (1995); A. de Luca, M. Weller, A. Fontana, J. Neurosci. 16, 4174 (1996).
-
(1993)
Neuroscience
, vol.57
, pp. 965
-
-
Enokido, Y.1
Hatanaka, H.2
-
11
-
-
0028824798
-
-
V. Gallo, A. Kingsbury, R. Balázs, O. S. Jorgensen, J. Neurosci. 7, 2203 (1987); J. L. Franklin and E. M. Johnson Jr., Trends Neurosci. 15, 501 (1992); Y. Enokido and H. Hatanaka, Neuroscience 57, 965 (1993); J-Y. Koh et al., Exp. Neurol. 135, 153 (1995); A. de Luca, M. Weller, A. Fontana, J. Neurosci. 16, 4174 (1996).
-
(1995)
Exp. Neurol.
, vol.135
, pp. 153
-
-
Koh, J.-Y.1
-
12
-
-
0029897649
-
-
V. Gallo, A. Kingsbury, R. Balázs, O. S. Jorgensen, J. Neurosci. 7, 2203 (1987); J. L. Franklin and E. M. Johnson Jr., Trends Neurosci. 15, 501 (1992); Y. Enokido and H. Hatanaka, Neuroscience 57, 965 (1993); J-Y. Koh et al., Exp. Neurol. 135, 153 (1995); A. de Luca, M. Weller, A. Fontana, J. Neurosci. 16, 4174 (1996).
-
(1996)
J. Neurosci.
, vol.16
, pp. 4174
-
-
De Luca, A.1
Weller, M.2
Fontana, A.3
-
13
-
-
0024711746
-
-
T. Koike, D. P. Martin, E. M. Johnson Jr., Proc. Natl. Acad. Sci. U.S.A. 86, 6421 (1989); E. M. Johnson Jr., T. Koike, J. Franklin, Exp. Neurol. 115, 163 (1992); J. L. Franklin, C. Sanz-Rodriguez, A. Juhasz, T. L. Deckwerth, E. M. Johnson Jr., J. Neurosci. 15, 643 (1995).
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 6421
-
-
Koike, T.1
Martin, D.P.2
Johnson Jr., E.M.3
-
14
-
-
0026584043
-
-
T. Koike, D. P. Martin, E. M. Johnson Jr., Proc. Natl. Acad. Sci. U.S.A. 86, 6421 (1989); E. M. Johnson Jr., T. Koike, J. Franklin, Exp. Neurol. 115, 163 (1992); J. L. Franklin, C. Sanz-Rodriguez, A. Juhasz, T. L. Deckwerth, E. M. Johnson Jr., J. Neurosci. 15, 643 (1995).
-
(1992)
Exp. Neurol.
, vol.115
, pp. 163
-
-
Johnson Jr., E.M.1
Koike, T.2
Franklin, J.3
-
15
-
-
0028831283
-
-
T. Koike, D. P. Martin, E. M. Johnson Jr., Proc. Natl. Acad. Sci. U.S.A. 86, 6421 (1989); E. M. Johnson Jr., T. Koike, J. Franklin, Exp. Neurol. 115, 163 (1992); J. L. Franklin, C. Sanz-Rodriguez, A. Juhasz, T. L. Deckwerth, E. M. Johnson Jr., J. Neurosci. 15, 643 (1995).
-
(1995)
J. Neurosci.
, vol.15
, pp. 643
-
-
Franklin, J.L.1
Sanz-Rodriguez, C.2
Juhasz, A.3
Deckwerth, T.L.4
Johnson Jr., E.M.5
-
17
-
-
0028834166
-
-
P. A. Lampe, E. B. Cornbrooks, A. Juhasz, E. M. Johnson Jr., J. L. Franklin, J. Neurobiol. 26, 205 (1995).
-
(1995)
J. Neurobiol.
, vol.26
, pp. 205
-
-
Lampe, P.A.1
Cornbrooks, E.B.2
Juhasz, A.3
Johnson Jr., E.M.4
Franklin, J.L.5
-
18
-
-
0028175464
-
-
N. Takei and Y. Endo, Brain Res. 652, 65 (1994); D. J. McConkey and S. Orrenius, J. Leukocyte Biol. 59, 775 (1996).
-
(1994)
Brain Res.
, vol.652
, pp. 65
-
-
Takei, N.1
Endo, Y.2
-
21
-
-
0001884447
-
-
C. A. Tyson and J. M. Frazier, Eds. Academic Press, San Diego, CA
-
K. Rose, M. P. Goldberg, D. W. Choi, in Methods in Toxicology, C. A. Tyson and J. M. Frazier, Eds. (Academic Press, San Diego, CA, 1993), pp. 46-60.
-
(1993)
Methods in Toxicology
, pp. 46-60
-
-
Rose, K.1
Goldberg, M.P.2
Choi, D.W.3
-
22
-
-
0029065517
-
-
J-Y. Koh, B. J. Gwag, D. Lobner, D. W. Choi, Science 268, 573 (1995).
-
(1995)
Science
, vol.268
, pp. 573
-
-
Koh, J.-Y.1
Gwag, B.J.2
Lobner, D.3
Choi, D.W.4
-
23
-
-
1842274536
-
-
note
-
2ATP. Experiments were performed at room temperature (21° to 22°C) and pH 7.3.
-
-
-
-
25
-
-
0014089361
-
-
B. Hille, J. Gen. Physiol. 50, 1287 (1967); E. Neher and H. D. Lux, Pfluegers Arch. 336, 87 (1972).
-
(1967)
J. Gen. Physiol.
, vol.50
, pp. 1287
-
-
Hille, B.1
-
27
-
-
1842395902
-
-
note
-
+-sensitive electrode). Even 9 hours after the onset of serum deprivation, intracellular lactate dehydrogenase and total protein content remained normal, which is an argument against nonspecific membrane leakage or cell death.
-
-
-
-
28
-
-
1842304312
-
-
in press
-
J. W. McDonald, M. I. Behrens, C. Chung, T. Bhattacharyya, D. W. Choi, Brain Res., in press.
-
Brain Res.
-
-
McDonald, J.W.1
Behrens, M.I.2
Chung, C.3
Bhattacharyya, T.4
Choi, D.W.5
-
29
-
-
1842281322
-
-
unpublished data
-
Apoptosis was detected by DNA fragmentation (10) and cellular alterations. For electron microscopy, cultures were fixed and then embedded. Sections were cut and stained with lead citrate and uranyl acetate. Cells were examined and photographed with a JEOL 100 CS electron microscope. Tested by applying cycloheximide, phorbol 12-myristate 13-acetate, or BDNF, or re-adding serum, the commitment point for most neurons to die was ≳ 10 hours after apoptotic insults (M.I. Behrens, C. Csernansky, Dugan, D. W. Choi, unpublished data).
-
-
-
Behrens, M.I.1
Csernansky, C.2
Dugan3
Choi, D.W.4
-
31
-
-
1842350321
-
-
note
-
d of 225 nM was used in the ratio method formula.
-
-
-
-
33
-
-
0023841072
-
-
N. L. Allbritton, C. R. Verret, R. C. Wolley, H. N. Eisen, J. Exp. Med. 167, 514 (1988); D. M. Ojcius, A. Zychlinsky, L. M. Zheng, J. D.-E. Young, Exp. Cell Res. 197, 43 (1991); C. L. P. Deckers, A. B. Lyons, K. Samuel, A. Sanderson, A. H. Maddy, ibid. 208, 362 (1993); R. C. Duke, R. Z. Witter, P. B. Nash, J. D.-E. Young, D. M. Ojcius, FASEB J. 8, 237 (1994).
-
(1988)
J. Exp. Med.
, vol.167
, pp. 514
-
-
Allbritton, N.L.1
Verret, C.R.2
Wolley, R.C.3
Eisen, H.N.4
-
34
-
-
0025933101
-
-
N. L. Allbritton, C. R. Verret, R. C. Wolley, H. N. Eisen, J. Exp. Med. 167, 514 (1988); D. M. Ojcius, A. Zychlinsky, L. M. Zheng, J. D.-E. Young, Exp. Cell Res. 197, 43 (1991); C. L. P. Deckers, A. B. Lyons, K. Samuel, A. Sanderson, A. H. Maddy, ibid. 208, 362 (1993); R. C. Duke, R. Z. Witter, P. B. Nash, J. D.-E. Young, D. M. Ojcius, FASEB J. 8, 237 (1994).
-
(1991)
Exp. Cell Res.
, vol.197
, pp. 43
-
-
Ojcius, D.M.1
Zychlinsky, A.2
Zheng, L.M.3
Young, J.D.-E.4
-
35
-
-
0027491918
-
-
N. L. Allbritton, C. R. Verret, R. C. Wolley, H. N. Eisen, J. Exp. Med. 167, 514 (1988); D. M. Ojcius, A. Zychlinsky, L. M. Zheng, J. D.-E. Young, Exp. Cell Res. 197, 43 (1991); C. L. P. Deckers, A. B. Lyons, K. Samuel, A. Sanderson, A. H. Maddy, ibid. 208, 362 (1993); R. C. Duke, R. Z. Witter, P. B. Nash, J. D.-E. Young, D. M. Ojcius, FASEB J. 8, 237 (1994).
-
(1993)
Exp. Cell Res.
, vol.208
, pp. 362
-
-
Deckers, C.L.P.1
Lyons, A.B.2
Samuel, K.3
Sanderson, A.4
Maddy, A.H.5
-
36
-
-
0028013217
-
-
N. L. Allbritton, C. R. Verret, R. C. Wolley, H. N. Eisen, J. Exp. Med. 167, 514 (1988); D. M. Ojcius, A. Zychlinsky, L. M. Zheng, J. D.-E. Young, Exp. Cell Res. 197, 43 (1991); C. L. P. Deckers, A. B. Lyons, K. Samuel, A. Sanderson, A. H. Maddy, ibid. 208, 362 (1993); R. C. Duke, R. Z. Witter, P. B. Nash, J. D.-E. Young, D. M. Ojcius, FASEB J. 8, 237 (1994).
-
(1994)
FASEB J.
, vol.8
, pp. 237
-
-
Duke, R.C.1
Witter, R.Z.2
Nash, P.B.3
Young, J.D.-E.4
Ojcius, D.M.5
-
38
-
-
0025110531
-
-
C. Deutsch, Prog. Clin. Biol. Res. 334, 251 (1990); B. Rouzaire-Duboisand J-M. Dubois, Cell Signal 3, 333 (1991).
-
(1990)
Prog. Clin. Biol. Res.
, vol.334
, pp. 251
-
-
Deutsch, C.1
-
40
-
-
0022552536
-
-
S. C. Lee, D. E. Sabath, C. Deutsch, M. B. Prystowsky, J. Cell Biol. 102, 1200 (1986); T. Konishi, J. Physiol. (London) 411, 115 (1989).
-
(1986)
J. Cell Biol.
, vol.102
, pp. 1200
-
-
Lee, S.C.1
Sabath, D.E.2
Deutsch, C.3
Prystowsky, M.B.4
-
41
-
-
0024538417
-
-
S. C. Lee, D. E. Sabath, C. Deutsch, M. B. Prystowsky, J. Cell Biol. 102, 1200 (1986); T. Konishi, J. Physiol. (London) 411, 115 (1989).
-
(1989)
J. Physiol. (London)
, vol.411
, pp. 115
-
-
Konishi, T.1
-
43
-
-
0028949817
-
-
G. Barbiero, F. Duranti, G. Bonelli, J. S. Amenta, F. M. Baccino, Exp. Cell Res. 217, 410 (1995).
-
(1995)
Exp. Cell Res.
, vol.217
, pp. 410
-
-
Barbiero, G.1
Duranti, F.2
Bonelli, G.3
Amenta, J.S.4
Baccino, F.M.5
-
45
-
-
0017280397
-
-
C. D. Cone Jr. and C. M. Cone, Science 192, 155 (1976); T. E. DeCoursey, K. G. Chandy, S. Gupta, M. D. Cahalan, Nature 307, 465 (1984).
-
(1976)
Science
, vol.192
, pp. 155
-
-
Cone Jr., C.D.1
Cone, C.M.2
-
46
-
-
0021271521
-
-
C. D. Cone Jr. and C. M. Cone, Science 192, 155 (1976); T. E. DeCoursey, K. G. Chandy, S. Gupta, M. D. Cahalan, Nature 307, 465 (1984).
-
(1984)
Nature
, vol.307
, pp. 465
-
-
DeCoursey, T.E.1
Chandy, K.G.2
Gupta, S.3
Cahalan, M.D.4
-
47
-
-
0025754446
-
-
D. S. Ucker, New Biol. 3, 103 (1991); G. Ferrari and L. A. Greene, EMBO J. 13, 5922 (1994); N. Heintz, Trends Biochem. Sci. 18, 157 (1993); L. L. Rubin, K. L. Philpott, S. F. Brooks, Curr. Biol. 3, 391 (1993); G. Kroemer, P. Petit, N. Zamzami, J-L. Vayssière, B. Mignotte, FASEB J. 9, 1277 (1995).
-
(1991)
New Biol.
, vol.3
, pp. 103
-
-
Ucker, D.S.1
-
48
-
-
0028607141
-
-
D. S. Ucker, New Biol. 3, 103 (1991); G. Ferrari and L. A. Greene, EMBO J. 13, 5922 (1994); N. Heintz, Trends Biochem. Sci. 18, 157 (1993); L. L. Rubin, K. L. Philpott, S. F. Brooks, Curr. Biol. 3, 391 (1993); G. Kroemer, P. Petit, N. Zamzami, J-L. Vayssière, B. Mignotte, FASEB J. 9, 1277 (1995).
-
(1994)
EMBO J.
, vol.13
, pp. 5922
-
-
Ferrari, G.1
Greene, L.A.2
-
49
-
-
0027178335
-
-
D. S. Ucker, New Biol. 3, 103 (1991); G. Ferrari and L. A. Greene, EMBO J. 13, 5922 (1994); N. Heintz, Trends Biochem. Sci. 18, 157 (1993); L. L. Rubin, K. L. Philpott, S. F. Brooks, Curr. Biol. 3, 391 (1993); G. Kroemer, P. Petit, N. Zamzami, J-L. Vayssière, B. Mignotte, FASEB J. 9, 1277 (1995).
-
(1993)
Trends Biochem. Sci.
, vol.18
, pp. 157
-
-
Heintz, N.1
-
50
-
-
0000177556
-
-
D. S. Ucker, New Biol. 3, 103 (1991); G. Ferrari and L. A. Greene, EMBO J. 13, 5922 (1994); N. Heintz, Trends Biochem. Sci. 18, 157 (1993); L. L. Rubin, K. L. Philpott, S. F. Brooks, Curr. Biol. 3, 391 (1993); G. Kroemer, P. Petit, N. Zamzami, J-L. Vayssière, B. Mignotte, FASEB J. 9, 1277 (1995).
-
(1993)
Curr. Biol.
, vol.3
, pp. 391
-
-
Rubin, L.L.1
Philpott, K.L.2
Brooks, S.F.3
-
51
-
-
0028847003
-
-
D. S. Ucker, New Biol. 3, 103 (1991); G. Ferrari and L. A. Greene, EMBO J. 13, 5922 (1994); N. Heintz, Trends Biochem. Sci. 18, 157 (1993); L. L. Rubin, K. L. Philpott, S. F. Brooks, Curr. Biol. 3, 391 (1993); G. Kroemer, P. Petit, N. Zamzami, J-L. Vayssière, B. Mignotte, FASEB J. 9, 1277 (1995).
-
(1995)
FASEB J.
, vol.9
, pp. 1277
-
-
Kroemer, G.1
Petit, P.2
Zamzami, N.3
Vayssière, J.-L.4
Mignotte, B.5
-
52
-
-
0028175838
-
-
D. Perregaux and C. A. Gabel, J. Biol. Chem. 269, 15195 (1994); I. Walev, K. Reske, M. Palmer, A. Valeva, S. Bhakdi, EMBO J. 14, 1607 (1995).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 15195
-
-
Perregaux, D.1
Gabel, C.A.2
-
53
-
-
0028989337
-
-
D. Perregaux and C. A. Gabel, J. Biol. Chem. 269, 15195 (1994); I. Walev, K. Reske, M. Palmer, A. Valeva, S. Bhakdi, EMBO J. 14, 1607 (1995).
-
(1995)
EMBO J.
, vol.14
, pp. 1607
-
-
Walev, I.1
Reske, K.2
Palmer, M.3
Valeva, A.4
Bhakdi, S.5
-
55
-
-
1842390053
-
-
note
-
This work was supported by NIH grant 30337 (D.W.C.).
-
-
-
|