Potassium channels as tumour markers

FEBS Letters

Volumn 580, Issue 12, 2006, Pages 2850-2852

  Stühmer, Walter ^a   Alves, Frauke ^b   Hartung, Franziska ^a   Zientkowska, Marta ^b   Pardo, Luis A ^a  

^a MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

Cancer; EAG; Ion channels; Near infrared imaging; Oncogene

Indexed keywords

ANTINEOPLASTIC AGENT; ASTEMIZOLE; CESIUM; CYCLIC AMP; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FLUORESCENT DYE; IMIPRAMINE; IMMUNOGLOBULIN F(AB) FRAGMENT; ISOFLURANE; ISOPROTEIN; MAGNESIUM; MONOCLONAL ANTIBODY; POLYLYSINE; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL HERG; SODIUM; TRICYCLIC ANTIDEPRESSANT AGENT; TUMOR MARKER;

CANCER; CELL CYCLE; CELL PROLIFERATION; DROSOPHILA; DRUG MECHANISM; ELECTROPHYSIOLOGY; HUMAN; IN VIVO STUDY; MICROTUBULE ASSEMBLY; MITOSIS; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; SHORT SURVEY; TUMOR GROWTH;

ANTIBODIES; CELL CYCLE; CELL PROLIFERATION; ETHER-A-GO-GO POTASSIUM CHANNELS; FLUORESCENT DYES; HUMANS; TUMOR MARKERS, BIOLOGICAL;

EID: 33646568826     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.03.062     Document Type: Short Survey

References (33)

1. + channel block-induced mammalian neuroblastoma cell swelling - a possible mechanism to influence proliferation. J. Physiol. 510 (1998) 93-102
2. Pardo L.A. Voltage-gated potassium channels in cell proliferation. Physiology (Bethesda) 19 (2004) 285-292
3. Caterall W., Chandy G., and Gutman G. The IUPHAR Compendium of Voltage-gated Ion Channels (2002), IUPHAR Media, Leeds, UK
4. + channels in human T lymphocytes: a role in mitogenesis?. Nature 307 (1984) 465-468
5. Abdul M., and Hoosein N. Expression and activity of potassium ion channels in human prostate cancer. Cancer Lett. 186 (2002) 99-105
6. 1-integrins on the plasma membrane of melanoma cells: effects of cell adherence and channel blockers. J. Gen. Physiol. 120 (2002) 29-37
7. + channel subunit in rat prostate cancer cell lines: electrophysiological, pharmacological and molecular characterisation. Pflugers Archiv. - Eur. J. Physiol. 446 (2003) 559-571
8. Abdul M., Santo A., and Hoosein N. Activity of potassium channel-blockers in breast cancer. Anticancer Res. 23 (2003) 3347-3351
9. +-channel modulators on human prostate cancer cell proliferation. Eur. J. Pharmacol. 471 (2003) 157-164
10. Mu D., Chen L.Y., Zhang X.P., See L.H., Koch C.M., Yen C., Tong J.J., Spiegel L., Nguyen K.C.Q., Servoss A., Peng Y., Pei L., Marks J.R., Lowe S., Hoey T., Jan L.Y., McCombie W.R., Wigler M.H., and Powers S. Genomic amplification and oncogenic properties of the KCNK9 potassium channel gene. Cancer Cell 3 (2003) 297-302
11. + current highly conserved in tumors of different histogenesis - a selective advantage for cancer cells?. Cancer Res. 58 (1998) 815-822
12. Cherubini A., Taddei G.L., Crociani O., Paglierani M., Buccoliero A.M., Fontana L., Noci I., Borri P., Borrani E., Giachi M., Becchetti A., Rosati B., Wanke E., Olivotto M., and Arcangeli A. HERG potassium channels are more frequently expressed in human endometrial cancer as compared to non-cancerous endometrium. Br. J. Cancer 83 (2000) 1722-1729
13. + channels in neoplastic hematopoietic cells. J. Biol. Chem. 277 (2002) 18528-18534
14. Crociani O., Guasti L., Balzi M., Becchetti A., Wanke E., Olivotto M., Wymore R.S., and Arcangeli A. Cell cycle-dependent expression of HERG1 and HERG1B isoforms in tumor cells. J. Biol. Chem. 278 (2003) 2947-2955
15. Lastraioli E., Guasti L., Crociani O., Polvani S., Hofmann G., Witchel H., Bencini L., Calistri M., Messerini L., Scatizzi M., Moretti R., Wanke E., Olivotto M., Mugnai G., and Arcangeli A. herg1 gene and HERG1 protein are overexpressed in colorectal cancers and regulate cell invasion of tumor cells. Cancer Res. 64 (2004) 606-611
16. + channels. EMBO J. 18 (1999) 5540-5547
17. Meyer R., Schonherr R., Gavrilova-Ruch O., Wohlrab W., and Heinemann S.H. Identification of ether a go-go and calcium-activated potassium channels in human melanoma cells. J. Memb. Biol. 171 (1999) 107-115
18. Farias L.M., Ocaña D.B., Diaz L., Larrea F., Avila-Chavez E., Cadena A., Hinojosa L.M., Lara G., Villanueva L.A., Vargas C., Hernandez-Gallegos E., Camacho-Arroyo I., Dueñas-Gonzalez A., Perez-Cardenas E., Pardo L.A., Morales A., Taja-Chayeb L., Escamilla J., Sanchez-Peña C., and Camacho J. Ether a go-go potassium channels as human cervical cancer markers. Cancer Res. 64 (2004) 6996-7001
19. Ludwig J., Terlau H., Wunder F., Brüggemann A., Pardo L.A., Marquardt A., Stühmer W., and Pongs O. Functional expression of a rat homologue of the voltage gated ether a go-go potassium channel reveals differences in selectivity and activation kinetics between the Drosophila channel and its mammalian counterpart. EMBO J. 13 (1994) 4451-4458
20. 2+ and modulated by cAMP. Nature 365 (1993) 445-448
21. Terlau H., Ludwig J., Steffan R., Pongs O., Stühmer W., and Heinemann S.H. Extracellular Mg2+ regulates activation of rat eag potassium channel. Pflugers Arch. 432 (1996) 301-312
22. Brüggemann A., Stühmer W., and Pardo L.A. Mitosis-promoting factor-mediated suppression of a cloned delayed rectifier potassium channel expressed in Xenopus oocytes. Proc. Natl. Acad. Sci. USA 94 (1997) 537-542
23. + channels. J. Cell. Biol. 143 (1998) 767-775
24. Camacho J., Sánchez A., Stühmer W., and Pardo L.A. Cytoskeletal interactions determine the electrophysiological properties of human EAG potassium channels. Pflugers Archiv. - Eur. J. Physiol. 441 (2000) 167-174
25. Jenke M., Sanchez A., Monje F., Stühmer W., Weseloh R.M., and Pardo L.A. C-terminal domains implicated in the functional surface expression of potassium channels. EMBO J. 22 (2003) 395-403
26. Zerangue N., Schwappach B., Jan Y.N., and Jan L.Y. A new ER trafficking signal regulates the subunit stoichiometry of plasma membrane K-ATP channels. Neuron 22 (1999) 537-548
27. Napp J., Monje F., Stühmer W., and Pardo L.A. Glycosylation of Eag1 (Kv10.1) potassium channels: intracellular trafficking and functional consequences. J. Biol. Chem. 280 (2005) 29506-29512
28. Ouadid-Ahidouch H., Le Bourhis X., Roudbaraki M., Toillon R.A., Delcourt P., and Prevarskaya N. Changes in the K+ current-density of MCF-7 cells during progression through the cell cycle: Possible involvement of a h-ether a-gogo K+ channel. Receptors Channels 7 (2001) 345-356
29. Gavrilova-Ruch O., Schönherr K., Gessner G., Schönherr R., Klapperstuck T., Wohlrab W., and Heinemann S.H. Effects of imipramine on ion channels and proliferation of IGR1 melanoma cells. J. Membr. Biol. 188 (2002) 137-149
30. Garcia-Ferreiro R.E., Kerschensteiner D., Major F., Monje F., Stühmer W., and Pardo L.A. Mechanism of block of hEag1 K+ channels by imipramine and astemizole. J. Gen. Physiol. 124 (2004) 301-317
31. Livingston R.B., and Esteva F.J. Chemotherapy and herceptin for HER-2+ metastatic breast cancer. The Oncologist 6 (2001) 315-316
32. Frangioni J.V. In vivo near-infrared fluorescence imaging. Curr. Opin. Chem. Biol. 7 (2003) 626-634
33. Pardo L.A., Contreras-Jurado C., Zientkowska M., Alves F., and Stühmer W. Role of voltage-gated potassium channels in cancer. J. Membr. Biol. 205 (2005) 115-124