Lessons from the heart: Mirroring electrophysiological characteristics during cardiac development to in vitro differentiation of stem cell derived cardiomyocytes

Journal of Molecular and Cellular Cardiology

Volumn 67, Issue , 2014, Pages 12-25

  Van Den Heuvel, Nikki H L ^a   Van Veen, Toon A B ^a   Lim, Bing ^b   Jonsson, Malin K B ^a,b  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b GENOME INSTITUTE OF SINGAPORE   (Singapore)

Author keywords

Cardiac development; Cardiomyocyte; Differentiation; Pluripotent stem cell

Indexed keywords

CALCIUM ION;

CELL DIFFERENTIATION; CELL MATURATION; CELL TYPE; DEVELOPMENTAL STAGE; FETUS DEVELOPMENT; HEART DEVELOPMENT; HEART ELECTROPHYSIOLOGY; HEART MUSCLE CELL; HEART MUSCLE CONTRACTILITY; HEART VENTRICLE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LARGE SCALE PRODUCTION; MESODERM; NONHUMAN; PLURIPOTENT STEM CELL; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; REGENERATIVE MEDICINE; REVIEW; TRANSCRIPTION REGULATION;

ACETHYLCHOLINE ACTIVATED POTASSIUM CURRENT; ACTION POTENTIAL; AP; ATP SENSITIVE POTASSIUM CURRENT; CALCIUM INDUCED CALCIUM RELEASE; CARDIAC DEVELOPMENT; CARDIOMYOCYTE; CICR; CM; DIFFERENTIATION; FUNNY OR PACEMAKER CURRENT; HEART FAILURE; HESC; HF; HIPSC; HPSC; HUMAN EMBRYONIC STEM CELL; HUMAN INDUCED PLURIPOTENT STEM CELL; HUMAN PLURIPOTENT STEM CELL (EITHER HESC AND/OR HIPSC); I(CA,L); I(CA,T); I(F); I(K,ACH); I(K,ATP); I(K1); I(KR); I(KS); I(KUR); I(NA); I(TO); INWARD RECTIFIER POTASSIUM CURRENT; L-TYPE CALCIUM CURRENT; LNCRNA; LONG NON-CODING RNA; MI; MICRORNA; MIRNA; MYOCARDIAL INFARCTION; PLURIPOTENT STEM CELL; RAPID DELAYED RECTIFIER POTASSIUM CURRENT; RESTING MEMBRANE POTENTIAL; RMP; SARCOPLASMATIC RETICULUM; SLOW DELAYED RECTIFIER POTASSIUM CURRENT; SODIUM CURRENT; SR; T-TYPE CALCIUM CURRENT; TRANSIENT OUTWARD POTASSIUM CURRENT; ULTRARAPID DELAYED RECTIFIER POTASSIUM CURRENT;

CELL DIFFERENTIATION; CULTURE TECHNIQUES; ELECTROPHYSIOLOGICAL PHENOMENA; EPIGENOMICS; HEART; HUMANS; MYOCYTES, CARDIAC; PLURIPOTENT STEM CELLS; SIGNAL TRANSDUCTION;

EID: 84892884582     PISSN: 00222828     EISSN: 10958584     Source Type: Journal    
DOI: 10.1016/j.yjmcc.2013.12.011     Document Type: Review

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