In vivo differentiation of induced pluripotent stem cell-derived cardiomyocytes

Circulation Journal

Volumn 77, Issue 5, 2013, Pages 1297-1306

  Yu, Tao ^a   Miyagawa, Shigeru ^a   Miki, Kenji ^a   Saito, Atsuhiro ^b   Fukushima, Satsuki ^a   Higuchi, Takahiro ^a   Kawamura, Masashi ^a   Kawamura, Takuji ^a   Ito, Emiko ^a   Kawaguchi, Naomasa ^a   Sawa, Yoshiki ^a   Matsuura, Nariaki ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY HOSPITAL   (Japan)

Author keywords

Adhesion molecules; Cardiomyocyte differentiation; Cytoskeleton; Induced pluripotent tem cells; Ultrastructure

Indexed keywords

ALPHA DYSTROGLYCAN; ALPHA SARCOGLYCAN; ALPHA7 INTEGRIN; CONNEXIN 43; DYSTROPHIN; GROWTH HORMONE; LAMININ ALPHA2; MYOSIN HEAVY CHAIN BETA; MYOSIN LIGHT CHAIN 2; NERVE CELL ADHESION MOLECULE; SCATTER FACTOR; SOMATOMEDIN C; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NKX2.2; TROPONIN T;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL CULTURE; CELL DIFFERENTIATION; CELL ISOLATION; CELL ULTRASTRUCTURE; CONTROLLED STUDY; ELECTRON MICROSCOPY; EMBRYOID BODY; FEMALE; HEART MUSCLE CELL; IMMUNOFLUORESCENCE TEST; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NEWBORN; NONHUMAN; PLURIPOTENT STEM CELL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEM CELL TRANSPLANTATION; WESTERN BLOTTING;

ANIMALS; ANIMALS, NEWBORN; BIOLOGICAL MARKERS; CELL ADHESION MOLECULES; CELL DIFFERENTIATION; CELL LINE; CELL LINEAGE; FEMALE; IMMUNOHISTOCHEMISTRY; INDUCED PLURIPOTENT STEM CELLS; INSULIN-LIKE GROWTH FACTOR I; MECHANOTRANSDUCTION, CELLULAR; MICE; MICE, INBRED C57BL; MICROSCOPY, ELECTRON, TRANSMISSION; MYOCARDIAL CONTRACTION; MYOCYTES, CARDIAC; MYOSIN HEAVY CHAINS; MYOSIN LIGHT CHAINS; PHENOTYPE; RATS; RATS, INBRED F344; RATS, NUDE; STRESS, MECHANICAL; TIME FACTORS;

EID: 84876767072     PISSN: 13469843     EISSN: 13474820     Source Type: Journal    
DOI: 10.1253/circj.CJ-12-0977     Document Type: Article

References (36)

1. Towbin JA, Bowles NE. The failing heart. Nature 2002; 415: 227-233.
2. Hosseinkhani M, Hasegawa K, Ono K, Kawamura T, Takaya T, Morimoto T, et al. Trichostatin A induces myocardial differentiation of monkey ES cells. Biochem Biophys Res Commun 2007; 356: 386-391.
3. Dimmeler S, Zeiher AM, Schneider MD. Unchain my heart: The scientific foundations of cardiac repair. J Clin Invest 2005; 115: 572-583.
4. Dinsmore J, Ratliff J, Deacon T, Pakzaban P, Jacoby D, Galpern W, et al. Embryonic stem cells differentiated in vitro as a novel source of cells for transplantation. Cell Transplant 1996; 5: 131-143.
5. Segers VF, Lee RT. Stem-cell therapy for cardiac disease. Nature 2008; 451: 937-942.
6. Fukuda K. Progress in myocardial regeneration and cell transplantation. Circ J 2005; 69: 1431-1446.
7. Uemura R, Xu M, Ahmad N, Ashraf M. Bone marrow stem cells prevent left ventricular remodeling of ischemic heart through paracrine signaling. Circ Res 2006; 98: 1414-1421.
8. Choi SH, Jung SY, Kwon SM, Baek SH. Perspectives on stem cell therapy for cardiac regeneration. Circ J 2012; 76: 1307-1312.
9. Perino MG, Yamanaka S, Li J, Wobus AM, Boheler KR. Cardiomyogenic stem and progenitor cell plasticity and the dissection of cardiopoiesis. J Mol Cell Cardiol 2008; 45: 475-494.
10. Yuasa S, Fukuda K. Cardiac regenerative medicine. Circ J 2008; 72: 49-55.
11. Chen H, Hattori F, Murata M, Li W, Yuasa S, Onizuka T, et al. Common marmoset embryonic stem cell can differentiate into cardiomyocytes. Biochem Biophys Res Commun 2008; 369: 801-806.
12. Iwamuro M, Komaki T, Kubota Y, Seita M, Kawamoto H, Yuasa T, et al. Comparative analysis of endoderm formation efficiency between mouse ES cells and iPS cells. Cell Transplant 2010; 19: 831-839.
13. Mandai M, Ikeda H, Jin ZB, Iseki K, Ishigami C, Takahashi M. Use of lectins to enrich mouse ES-derived retinal progenitor cells for the purpose of transplantation therapy. Cell Transplant 2010; 19: 9-19.
14. Li X, Yu X, Lin Q, Deng C, Shan Z, Yang M, et al. Bone marrow mesenchymal stem cells differentiate into functional cardiac phenotypes by cardiac microenvironment. J Mol Cell Cardiol 2007; 42: 295-303.
15. Reinecke H, Minami E, Zhu WZ, Laflamme MA. Cardiogenic differentiation and transdifferentiation of progenitor cells. Circ Res 2008; 103: 1058-1071.
16. Matsuda T, Takahashi K, Nariai T, Ito T, Takatani T, Fujio Y, et al. N-cadherin-mediated cell adhesion determines the plasticity for cell alignment in response to mechanical stretch in cultured cardiomyocytes. Biochem Biophys Res Commun 2005; 326: 228-232.
17. Sadoshima J, Jahn L, Takahashi T, Kulik TJ, Izumo S. Molecular characterization of the stretch-induced adaptation of cultured cardiac cells: An in vitro model of load-induced cardiac hypertrophy. J Biol Chem 1992; 267: 10551-10560.
18. Komuro I, Kaida T, Shibazaki Y, Kurabayashi M, Katoh Y, Hoh E, et al. Stretching cardiac myocytes stimulates protooncogene expression. J Biol Chem 1990; 65: 3595-3598.
19. Ruwhof C, van der Laarse A. Mechanical stress-induced cardiac hypertrophy: Mechanisms and signal transduction pathways. Cardiovasc Res 2000; 7: 23-37.
20. Shyu KG. Cellular and molecular effects of mechanical stretch on vascular cells and cardiac myocytes. Clin Sci Lond 2009; 16: 377-389.
21. Shyu KG, Ko WH, Yang WS, Wang BW, Kuan P. Insulin-like growth factor-1 mediates stretch-induced upregulation of myostatin expression in neonatal rat cardiomyocytes. Cardiovasc Res 2005; 68: 405-414.
22. Eschenhagen T, Didié M, Heubach J, Ravens U, Zimmermann WH. Cardiac tissue engineering. Transpl Immunol 2002; 9: 315-321.
23. Okita K, Ichisaka T, Yamanaka S. Generation of germline-competent induced pluripotent stem cells. Nature 2007; 48: 313-317.
24. Nakagawa M, Koyanagi M, Tanabe K, Takahashi K, Ichisaka T, Aoi T, et al. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 2008; 26: 101-106.
25. Naito AT, Shiojima I, Akazawa H, Hidaka K, Morisaki T, Kikuchi A, et al. Developmental stage-specific biphasic roles of Wnt/beta-catenin signaling in cardiomyogenesis and hematopoiesis. Proc Natl Acad Sci USA 2006; 103: 19812-19817.
26. Zhang CM, Gao L, Zheng YJ, Yang HT. Berbamine protects the heart from ischemia/reperfusion injury by maintaining cytosolic Ca2+ homeostasis and preventing calpain activation. Circ J 2012; 76: 1993-2002.
27. Miyagawa S, Saito A, Sakaguchi T, Yoshikawa Y, Yamauchi T, Imanishi Y, et al. Impaired myocardium regeneration with skeletal cell sheets--a preclinical trial for tissue-engineered regeneration therapy. Transplantation 2010; 90: 364-372.
28. Shyu KG, Chen CC, Wang BW, Kuan PL. Angiotensin II receptor antagonist blocks the expression of connexin43 induced by cyclical mechanical stretch in cultured neonatal rat cardiac myocytes. J Mol Cell Cardiol 2001; 3: 691-698.
29. Chang H, Wang BW, Kuan P, Shyu KG. Cyclical mechanical stretch enhances angiopoietin-2 and Tie2 receptor expression in cultured human umbilical vein endothelial cells. Clin Sci 2003; 104: 421-428.
30. Rajala K, Pekkanen-Mattila M, Aalto-Setälä K. Cardiac differentiation of pluripotent stem cells. Stem Cells Int 2011; 2011: 4061-4073.
31. Gao XR, Tan YZ, Wang HJ. Overexpression of Csx/Nkx2.5 and GATA-4 enhances the efficacy of mesenchymal stem cell transplantation after myocardial infarction. Circ J 2011; 75: 2683-2691.
32. Ozawa E, Mizuno Y, Hagiwara Y, Sasaoka T, Yoshida M. Molecular and cell biology of the sarcoglycan complex. Muscle Nerve 2005; 2: 563-576.
33. Aikawa R, Nagai T, Kudoh S, Zou Y, Tanaka M, Tamura M, et al. Integrins play a critical role in mechanical stress-induced p38 MAPK activation. Hypertension 2002; 9: 233-238.
34. Sadoshima J, Xu Y, Slayter HS, Izumo S. Autocrine release of angiotensin II mediates stretch-induced hypertrophy of cardiac myocytes in vitro. Cell 1993; 75: 977-984.
35. Nishi H, Ono K, Horie T, Nagao K, Kinoshita M, Kuwabara Y, et al. MicroRNA-27a regulates beta cardiac myosin heavy chain gene expression by targeting thyroid hormone receptor beta1 in neonatal rat ventricular myocytes. Mol Cell Biol 2011; 31: 744-755.
36. Gonzales C, Pedrazzini T. Progenitor cell therapy for heart disease. Exp Cell Res 2009; 315: 3077-3085