Mechanistic basis of excitation-contraction coupling in human pluripotent stem cell-derived ventricular cardiomyocytes revealed by Ca2+ spark characteristics: Direct evidence of functional Ca2+-induced Ca 2+ release

Heart Rhythm

Volumn 11, Issue 1, 2014, Pages 133-140

  Li, Sen ^a,b   Cheng, Heping ^c   Tomaselli, Gordon F ^d   Li, Ronald A ^a,b,e  

^a Stem Cell and Regenerative Medicine Consortium   (United States)

^b UNIVERSITY OF HONG KONG   (Hong Kong)

^c PEKING UNIVERSITY   (China)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Ca2+ sparks; Ca2+ waves; Ca2+ induced Ca2+ release; Stem cell; Ventricular cardiomyocytes

Indexed keywords

1,4 DIHYDRO 2,6 DIMETHYL 5 NITRO 4 [2 (TRIFLUOROMETHYL)PHENYL] 3 PYRIDINECARBOXYLIC ACID METHYL ESTER; 2 [2 [4 (4 NITROBENZYLOXY)PHENYL]ETHYL]ISOTHIOUREA METHANESULFONATE; 2 AMINOETHOXYDIPHENYLBORANE; 4 (2 BENZYLBENZOYL) 2,5 DIMETHYL 1H PYRROLE 3 CARBOXYLIC ACID METHYL ESTER; CALCIUM ION; CARBONYL CYANIDE CHLOROPHENYLHYDRAZONE; CYCLOPIAZONIC ACID; PHLEOMYCIN; RYANODINE; TETRACAINE; THAPSIGARGIN; XESTOSPONGIN C; CALCIUM; CALCIUM CHANNEL L TYPE;

ARTICLE; CALCIUM TRANSPORT; CELL COMPARTMENTALIZATION; CELL DIFFERENTIATION; CELL MEMBRANE PERMEABILITY; CYTOSOL; EMBRYO; EXCITATION CONTRACTION COUPLING; EXTRACELLULAR CALCIUM; HEART DEPOLARIZATION; HEART MUSCLE CELL; HEART MUSCLE POTENTIAL; HEART VENTRICLE; HUMAN; HUMAN CELL; MEMBRANE STEADY POTENTIAL; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRION; OXIDATIVE PHOSPHORYLATION UNCOUPLING; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM; CARDIAC MUSCLE CELL; CELL CULTURE; CYTOLOGY; HEART ARRHYTHMIA; METABOLISM; PATHOLOGY;

ARRHYTHMIAS, CARDIAC; CALCIUM; CALCIUM CHANNELS, L-TYPE; CELLS, CULTURED; EXCITATION CONTRACTION COUPLING; HEART VENTRICLES; HUMANS; MYOCYTES, CARDIAC; PLURIPOTENT STEM CELLS; SARCOPLASMIC RETICULUM;

EID: 84891668247     PISSN: 15475271     EISSN: 15563871     Source Type: Journal    
DOI: 10.1016/j.hrthm.2013.10.006     Document Type: Article

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