-
1
-
-
0014304603
-
Influence of dietary deprivations on plasma concentration of free amino acids of man
-
Adibi SA. Influence of dietary deprivations on plasma concentration of free amino acids of man. J Appl Physiol 25: 52-57, 1968.
-
(1968)
J Appl Physiol
, vol.25
, pp. 52-57
-
-
Adibi, S.A.1
-
2
-
-
0035846952
-
Regulation of glycogen synthesis by amino acids in cultured human muscle cells
-
Armstrong JL, Bonavaud SM, Toole BJ, Yeaman SJ. Regulation of glycogen synthesis by amino acids in cultured human muscle cells. J Biol Chem 276: 952-956, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 952-956
-
-
Armstrong, J.L.1
Bonavaud, S.M.2
Toole, B.J.3
Yeaman, S.J.4
-
3
-
-
0242285719
-
STAT proteins: From normal control of cellular events to tumorigenesis
-
Calo V, Migliavacca M, Bazan V, Macaluso M, Buscemi M, Gebbia N, Russo A. STAT proteins: from normal control of cellular events to tumorigenesis. J Cell Physiol 197: 157-168, 2003.
-
(2003)
J Cell Physiol
, vol.197
, pp. 157-168
-
-
Calo, V.1
Migliavacca, M.2
Bazan, V.3
McAluso, M.4
Buscemi, M.5
Gebbia, N.6
Russo, A.7
-
4
-
-
33645556312
-
Bax translocates to mitochondria of heart cells during simulated ischaemia: Involvement of AMP-activated and p38 mitogen-activated protein kinases
-
Capano M, Crompton M. Bax translocates to mitochondria of heart cells during simulated ischaemia: involvement of AMP-activated and p38 mitogen-activated protein kinases. Biochem J 395: 57-64, 2006.
-
(2006)
Biochem J
, vol.395
, pp. 57-64
-
-
Capano, M.1
Crompton, M.2
-
5
-
-
0347318052
-
The AMP-activated protein kinase cascade-a unifying system for energy control
-
Carling D. The AMP-activated protein kinase cascade-a unifying system for energy control. Trends Biochem Sci 29: 18-24, 2004.
-
(2004)
Trends Biochem Sci
, vol.29
, pp. 18-24
-
-
Carling, D.1
-
6
-
-
1942469564
-
Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status
-
Cheng SW, Fryer LG, Carling D, Shepherd PR. Thr2446 is a novel mammalian target of rapamycin (mTOR) phosphorylation site regulated by nutrient status. J Biol Chem 279: 15719-15722, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 15719-15722
-
-
Cheng, S.W.1
Fryer, L.G.2
Carling, D.3
Shepherd, P.R.4
-
7
-
-
79952717399
-
Insulin regulates GLUT1-mediated glucose transport in MG-63 human osteosarcoma cells
-
Cifuentes M, Garcia MA, Arrabal PM, Martinez F, Yanez MJ, Jara N, Weil B, Dominguez D, Medina RA, Nualart F. Insulin regulates GLUT1-mediated glucose transport in MG-63 human osteosarcoma cells. J Cell Physiol 226: 1425-1432, 2011.
-
(2011)
J Cell Physiol
, vol.226
, pp. 1425-1432
-
-
Cifuentes, M.1
Garcia, M.A.2
Arrabal, P.M.3
Martinez, F.4
Yanez, M.J.5
Jara, N.6
Weil, B.7
Dominguez, D.8
Medina, R.A.9
Nualart, F.10
-
8
-
-
45249122276
-
Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes
-
Cnop M. Fatty acids and glucolipotoxicity in the pathogenesis of Type 2 diabetes. Biochem Soc Trans 36: 348-352, 2008.
-
(2008)
Biochem Soc Trans
, vol.36
, pp. 348-352
-
-
Cnop, M.1
-
9
-
-
0014669160
-
Plasma amino acid levels and insulin secretion in obesity
-
Felig P, Marliss E, Cahill GF Jr. Plasma amino acid levels and insulin secretion in obesity. N Engl J Med 281: 811-816, 1969.
-
(1969)
N Engl J Med
, vol.281
, pp. 811-816
-
-
Felig, P.1
Marliss, E.2
Cahill Jr., G.F.3
-
10
-
-
0014945961
-
Are plasma amino acid levels elevated in obesity?
-
Felig P, Marliss E, Cahill GF Jr. Are plasma amino acid levels elevated in obesity? N Engl J Med 282: 166, 1970.
-
(1970)
N Engl J Med
, vol.282
, pp. 166
-
-
Felig, P.1
Marliss, E.2
Cahill Jr., G.F.3
-
11
-
-
0037097863
-
Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/ eIF4E
-
Fingar DC, Salama S, Tsou C, Harlow E, Blenis J. Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/ eIF4E. Genes Dev 16: 1472-1487, 2002.
-
(2002)
Genes Dev
, vol.16
, pp. 1472-1487
-
-
Fingar, D.C.1
Salama, S.2
Tsou, C.3
Harlow, E.4
Blenis, J.5
-
12
-
-
65549121943
-
Notch signaling: The core pathway and its posttranslational regulation
-
Fortini ME. Notch signaling: the core pathway and its posttranslational regulation. Dev Cell 16: 633-647, 2009.
-
(2009)
Dev Cell
, vol.16
, pp. 633-647
-
-
Fortini, M.E.1
-
13
-
-
0036824683
-
Protein and diabetes: Much advice, little research
-
Franz MJ. Protein and diabetes: much advice, little research. Curr Diab Rep 2: 457-464, 2002.
-
(2002)
Curr Diab Rep
, vol.2
, pp. 457-464
-
-
Franz, M.J.1
-
14
-
-
34447115914
-
Stimulation of glycogen synthesis and inactivation of phosphorylase in hepatocytes by serotonergic mechanisms, and counter-regulation by atypical antipsychotic drugs
-
Hampson LJ, Mackin P, Agius L. Stimulation of glycogen synthesis and inactivation of phosphorylase in hepatocytes by serotonergic mechanisms, and counter-regulation by atypical antipsychotic drugs. Diabetologia 50: 1743-1751, 2007.
-
(2007)
Diabetologia
, vol.50
, pp. 1743-1751
-
-
Hampson, L.J.1
McKin, P.2
Agius, L.3
-
15
-
-
0037178781
-
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
-
Hara K, Maruki Y, Long X, Yoshino K, Oshiro N, Hidayat S, Tokunaga C, Avruch J, Yonezawa K. Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action. Cell 110: 177-189, 2002.
-
(2002)
Cell
, vol.110
, pp. 177-189
-
-
Hara, K.1
Maruki, Y.2
Long, X.3
Yoshino, K.4
Oshiro, N.5
Hidayat, S.6
Tokunaga, C.7
Avruch, J.8
Yonezawa, K.9
-
16
-
-
0036213626
-
Role of mTOR in the degradation of IRS-1: Regulation of PP2A activity
-
Hartley D, Cooper GM. Role of mTOR in the degradation of IRS-1: regulation of PP2A activity. J Cell Biochem 85: 304-314, 2002.
-
(2002)
J Cell Biochem
, vol.85
, pp. 304-314
-
-
Hartley, D.1
Cooper, G.M.2
-
17
-
-
4043171462
-
Upstream and downstream of mTOR
-
Hay N, Sonenberg N. Upstream and downstream of mTOR. Genes Dev 18: 1926-1945, 2004.
-
(2004)
Genes Dev
, vol.18
, pp. 1926-1945
-
-
Hay, N.1
Sonenberg, N.2
-
18
-
-
84875450015
-
Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes
-
He C, Zhu H, Li H, Zou MH, Xie Z. Dissociation of Bcl-2-Beclin1 complex by activated AMPK enhances cardiac autophagy and protects against cardiomyocyte apoptosis in diabetes. Diabetes 62: 1270-1281, 2013.
-
(2013)
Diabetes
, vol.62
, pp. 1270-1281
-
-
He, C.1
Zhu, H.2
Li, H.3
Zou, M.H.4
Xie, Z.5
-
19
-
-
84880616033
-
7-Ketocholesterol induces autophagy in vascular smooth muscle cells through Nox4 and Atg4B
-
He C, Zhu H, Zhang W, Okon I, Wang Q, Li H, Le YZ, Xie Z. 7-Ketocholesterol induces autophagy in vascular smooth muscle cells through Nox4 and Atg4B. Am J Pathol 183: 626-637, 2013.
-
(2013)
Am J Pathol
, vol.183
, pp. 626-637
-
-
He, C.1
Zhu, H.2
Zhang, W.3
Okon, I.4
Wang, Q.5
Li, H.6
Le, Y.Z.7
Xie, Z.8
-
20
-
-
34548850880
-
Aldosterone suppresses insulin signaling via the downregulation of insulin receptor substrate-1 in vascular smooth muscle cells
-
Hitomi H, Kiyomoto H, Nishiyama A, Hara T, Moriwaki K, Kaifu K, Ihara G, Fujita Y, Ugawa T, Kohno M. Aldosterone suppresses insulin signaling via the downregulation of insulin receptor substrate-1 in vascular smooth muscle cells. Hypertension 50: 750-755, 2007.
-
(2007)
Hypertension
, vol.50
, pp. 750-755
-
-
Hitomi, H.1
Kiyomoto, H.2
Nishiyama, A.3
Hara, T.4
Moriwaki, K.5
Kaifu, K.6
Ihara, G.7
Fujita, Y.8
Ugawa, T.9
Kohno, M.10
-
21
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
-
Inoki K, Li Y, Zhu T, Wu J, Guan KL. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol 4: 648-657, 2002.
-
(2002)
Nat Cell Biol
, vol.4
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
Wu, J.4
Guan, K.L.5
-
22
-
-
7944235758
-
Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive
-
Jacinto E, Loewith R, Schmidt A, Lin S, Ruegg MA, Hall A, Hall MN. Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive. Nat Cell Biol 6: 1122-1128, 2004.
-
(2004)
Nat Cell Biol
, vol.6
, pp. 1122-1128
-
-
Jacinto, E.1
Loewith, R.2
Schmidt, A.3
Lin, S.4
Ruegg, M.A.5
Hall, A.6
Hall, M.N.7
-
23
-
-
0025117502
-
Insulin resistance is associated with reduced fasting and insulin-stimulated glycogen synthase phosphatase activity in human skeletal muscle
-
Kida Y, Esposito-Del PA, Bogardus C, Mott DM. Insulin resistance is associated with reduced fasting and insulin-stimulated glycogen synthase phosphatase activity in human skeletal muscle. J Clin Invest 85: 476-481, 1990.
-
(1990)
J Clin Invest
, vol.85
, pp. 476-481
-
-
Kida, Y.1
Esposito-Del, P.A.2
Bogardus, C.3
Mott, D.M.4
-
24
-
-
0037178786
-
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
Kim DH, Sarbassov DD, Ali SM, King JE, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell 110: 163-175, 2002.
-
(2002)
Cell
, vol.110
, pp. 163-175
-
-
Kim, D.H.1
Sarbassov, D.D.2
Ali, S.M.3
King, J.E.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
25
-
-
38149083478
-
Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway
-
Kim JH, Kim JE, Liu HY, Cao W, Chen J. Regulation of interleukin-6-induced hepatic insulin resistance by mammalian target of rapamycin through the STAT3-SOCS3 pathway. J Biol Chem 283: 708-715, 2008.
-
(2008)
J Biol Chem
, vol.283
, pp. 708-715
-
-
Kim, J.H.1
Kim, J.E.2
Liu, H.Y.3
Cao, W.4
Chen, J.5
-
26
-
-
72149126863
-
Signal transducer and activator of transcription 3 (STAT3) mediates amino acid inhibition of insulin signaling through serine 727 phosphorylation
-
Kim JH, Yoon MS, Chen J. Signal transducer and activator of transcription 3 (STAT3) mediates amino acid inhibition of insulin signaling through serine 727 phosphorylation. J Biol Chem 284: 35425-35432, 2009.
-
(2009)
J Biol Chem
, vol.284
, pp. 35425-35432
-
-
Kim, J.H.1
Yoon, M.S.2
Chen, J.3
-
27
-
-
0019843283
-
Mouse liver cell culture. II. Primary culture
-
Klaunig JE, Goldblatt PJ, Hinton DE, Lipsky MM, Trump BF. Mouse liver cell culture. II. Primary culture. In Vitro 17: 926-934, 1981.
-
(1981)
In Vitro
, vol.17
, pp. 926-934
-
-
Klaunig, J.E.1
Goldblatt, P.J.2
Hinton, D.E.3
Lipsky, M.M.4
Trump, B.F.5
-
28
-
-
0026040907
-
Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats
-
Kraegen EW, Clark PW, Jenkins AB, Daley EA, Chisholm DJ, Storlien LH. Development of muscle insulin resistance after liver insulin resistance in high-fat-fed rats. Diabetes 40: 1397-1403, 1991.
-
(1991)
Diabetes
, vol.40
, pp. 1397-1403
-
-
Kraegen, E.W.1
Clark, P.W.2
Jenkins, A.B.3
Daley, E.A.4
Chisholm, D.J.5
Storlien, L.H.6
-
29
-
-
0036313574
-
Mechanism of amino acid-induced skeletal muscle insulin resistance in humans
-
Krebs M, Krssak M, Bernroider E, Anderwald C, Brehm A, Meyerspeer M, Nowotny P, Roth E, Waldhausl W, Roden M. Mechanism of amino acid-induced skeletal muscle insulin resistance in humans. Diabetes 51: 599-605, 2002.
-
(2002)
Diabetes
, vol.51
, pp. 599-605
-
-
Krebs, M.1
Krssak, M.2
Bernroider, E.3
Anderwald, C.4
Brehm, A.5
Meyerspeer, M.6
Nowotny, P.7
Roth, E.8
Waldhausl, W.9
Roden, M.10
-
30
-
-
1842534924
-
Nutrient-induced insulin resistance in human skeletal muscle
-
Krebs M, Roden M. Nutrient-induced insulin resistance in human skeletal muscle. Curr Med Chem 11: 901-908, 2004.
-
(2004)
Curr Med Chem
, vol.11
, pp. 901-908
-
-
Krebs, M.1
Roden, M.2
-
31
-
-
77954713311
-
Effect of a high-protein diet on food intake and liver metabolism during pregnancy, lactation and after weaning in mice
-
Kuhla B, Kucia M, Gors S, Albrecht D, Langhammer M, Kuhla S, Metges CC. Effect of a high-protein diet on food intake and liver metabolism during pregnancy, lactation and after weaning in mice. Proteomics 10: 2573-2588, 2010.
-
(2010)
Proteomics
, vol.10
, pp. 2573-2588
-
-
Kuhla, B.1
Kucia, M.2
Gors, S.3
Albrecht, D.4
Langhammer, M.5
Kuhla, S.6
Metges, C.C.7
-
32
-
-
2942568513
-
Glucose utilization is essential for hypoxia-inducible factor 1 alpha-dependent phosphorylation of c-Jun
-
Laderoute KR, Calaoagan JM, Knapp M, Johnson RS. Glucose utilization is essential for hypoxia-inducible factor 1 alpha-dependent phosphorylation of c-Jun. Mol Cell Biol 24: 4128-4137, 2004.
-
(2004)
Mol Cell Biol
, vol.24
, pp. 4128-4137
-
-
Laderoute, K.R.1
Calaoagan, J.M.2
Knapp, M.3
Johnson, R.S.4
-
33
-
-
84869192260
-
Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice
-
Li H, Xu M, Lee J, He C, Xie Z. Leucine supplementation increases SIRT1 expression and prevents mitochondrial dysfunction and metabolic disorders in high-fat diet-induced obese mice. Am J Physiol Endocrinol Metab 303: E1234-E1244, 2012.
-
(2012)
Am J Physiol Endocrinol Metab
, vol.303
-
-
Li, H.1
Xu, M.2
Lee, J.3
He, C.4
Xie, Z.5
-
34
-
-
0033789795
-
Effect of long-term dietary protein intake on glucose metabolism in humans
-
Linn T, Santosa B, Gronemeyer D, Aygen S, Scholz N, Busch M, Bretzel RG. Effect of long-term dietary protein intake on glucose metabolism in humans. Diabetologia 43: 1257-1265, 2000.
-
(2000)
Diabetologia
, vol.43
, pp. 1257-1265
-
-
Linn, T.1
Santosa, B.2
Gronemeyer, D.3
Aygen, S.4
Scholz, N.5
Busch, M.6
Bretzel, R.G.7
-
35
-
-
33746564095
-
Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity
-
Luong N, Davies CR, Wessells RJ, Graham SM, King MT, Veech R, Bodmer R, Oldham SM. Activated FOXO-mediated insulin resistance is blocked by reduction of TOR activity. Cell Metab 4: 133-142, 2006.
-
(2006)
Cell Metab
, vol.4
, pp. 133-142
-
-
Luong, N.1
Davies, C.R.2
Wessells, R.J.3
Graham, S.M.4
King, M.T.5
Veech, R.6
Bodmer, R.7
Oldham, S.M.8
-
36
-
-
74949092824
-
Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade
-
Ma J, Meng Y, Kwiatkowski DJ, Chen X, Peng H, Sun Q, Zha X, Wang F, Wang Y, Jing Y, Zhang S, Chen R, Wang L, Wu E, Cai G, Malinowska-Kolodziej I, Liao Q, Liu Y, Zhao Y, Sun Q, Xu K, Dai J, Han J, Wu L, Zhao RC, Shen H, Zhang H. Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade. J Clin Invest 120: 103-114, 2010.
-
(2010)
J Clin Invest
, vol.120
, pp. 103-114
-
-
Ma, J.1
Meng, Y.2
Kwiatkowski, D.J.3
Chen, X.4
Peng, H.5
Sun, Q.6
Zha, X.7
Wang, F.8
Wang, Y.9
Jing, Y.10
Zhang, S.11
Chen, R.12
Wang, L.13
Wu, E.14
Cai, G.15
Malinowska-Kolodziej, I.16
Liao, Q.17
Liu, Y.18
Zhao, Y.19
Sun, Q.20
Xu, K.21
Dai, J.22
Han, J.23
Wu, L.24
Zhao, R.C.25
Shen, H.26
Zhang, H.27
more..
-
37
-
-
77950441537
-
Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells
-
Mazzone M, Selfors LM, Albeck J, Overholtzer M, Sale S, Carroll DL, Pandya D, Lu Y, Mills GB, Aster JC, Artavanis-Tsakonas S, Brugge JS. Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells. Proc Natl Acad Sci USA 107: 5012-5017, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 5012-5017
-
-
Mazzone, M.1
Selfors, L.M.2
Albeck, J.3
Overholtzer, M.4
Sale, S.5
Carroll, D.L.6
Pandya, D.7
Lu, Y.8
Mills, G.B.9
Aster, J.C.10
Artavanis-Tsakonas, S.11
Brugge, J.S.12
-
38
-
-
0036299982
-
Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes
-
Musi N, Hirshman MF, Nygren J, Svanfeldt M, Bavenholm P, Rooyackers O, Zhou G, Williamson JM, Ljunqvist O, Efendic S, Moller DE, Thorell A, Goodyear LJ. Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes. Diabetes 51: 2074-2081, 2002.
-
(2002)
Diabetes
, vol.51
, pp. 2074-2081
-
-
Musi, N.1
Hirshman, M.F.2
Nygren, J.3
Svanfeldt, M.4
Bavenholm, P.5
Rooyackers, O.6
Zhou, G.7
Williamson, J.M.8
Ljunqvist, O.9
Efendic, S.10
Moller, D.E.11
Thorell, A.12
Goodyear, L.J.13
-
39
-
-
63449111894
-
A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance
-
Newgard CB, An J, Bain JR, Muehlbauer MJ, Stevens RD, Lien LF, Haqq AM, Shah SH, Arlotto M, Slentz CA, Rochon J, Gallup D, Ilkayeva O, Wenner BR, Yancy WS Jr, Eisenson H, Musante G, Surwit RS, Millington DS, Butler MD, Svetkey LP. A branched-chain amino acid-related metabolic signature that differentiates obese and lean humans and contributes to insulin resistance. Cell Metab 9: 311-326, 2009.
-
(2009)
Cell Metab
, vol.9
, pp. 311-326
-
-
Newgard, C.B.1
An, J.2
Bain, J.R.3
Muehlbauer, M.J.4
Stevens, R.D.5
Lien, L.F.6
Haqq, A.M.7
Shah, S.H.8
Arlotto, M.9
Slentz, C.A.10
Rochon, J.11
Gallup, D.12
Ilkayeva, O.13
Wenner, B.R.14
Yancy Jr., W.S.15
Eisenson, H.16
Musante, G.17
Surwit, R.S.18
Millington, D.S.19
Butler, M.D.20
Svetkey, L.P.21
more..
-
40
-
-
79961173038
-
Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner
-
Pajvani UB, Shawber CJ, Samuel VT, Birkenfeld AL, Shulman GI, Kitajewski J, Accili D. Inhibition of Notch signaling ameliorates insulin resistance in a FoxO1-dependent manner. Nat Med 17: 961-967, 2011.
-
(2011)
Nat Med
, vol.17
, pp. 961-967
-
-
Pajvani, U.B.1
Shawber, C.J.2
Samuel, V.T.3
Birkenfeld, A.L.4
Shulman, G.I.5
Kitajewski, J.6
Accili, D.7
-
41
-
-
0034283186
-
L-leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: Evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-regulation of system A amino acid transport
-
Peyrollier K, Hajduch E, Blair AS, Hyde R, Hundal HS. L-leucine availability regulates phosphatidylinositol 3-kinase, p70 S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine-induced up-regulation of system A amino acid transport. Biochem J 350: 361-368, 2000.
-
(2000)
Biochem J
, vol.350
, pp. 361-368
-
-
Peyrollier, K.1
Hajduch, E.2
Blair, A.S.3
Hyde, R.4
Hundal, H.S.5
-
42
-
-
84858238974
-
GSK3beta regulates gluconeogenic gene expression through HNF4alpha and FOXO1
-
Sakamaki J, Daitoku H, Kaneko Y, Hagiwara A, Ueno K, Fukamizu A. GSK3beta regulates gluconeogenic gene expression through HNF4alpha and FOXO1. J Recept Signal Transduct Res 32: 96-101, 2012.
-
(2012)
J Recept Signal Transduct Res
, vol.32
, pp. 96-101
-
-
Sakamaki, J.1
Daitoku, H.2
Kaneko, Y.3
Hagiwara, A.4
Ueno, K.5
Fukamizu, A.6
-
43
-
-
3342895823
-
Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton
-
Sarbassov DD, Ali SM, Kim DH, Guertin DA, Latek RR, Erdjument-Bromage H, Tempst P, Sabatini DM. Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton. Curr Biol 14: 1296-1302, 2004.
-
(2004)
Curr Biol
, vol.14
, pp. 1296-1302
-
-
Sarbassov, D.D.1
Ali, S.M.2
Kim, D.H.3
Guertin, D.A.4
Latek, R.R.5
Erdjument-Bromage, H.6
Tempst, P.7
Sabatini, D.M.8
-
44
-
-
0344687175
-
Processed meat intake and incidence of Type 2 diabetes in younger and middle-aged women
-
Schulze MB, Manson JE, Willett WC, Hu FB. Processed meat intake and incidence of Type 2 diabetes in younger and middle-aged women. Diabetologia 46: 1465-1473, 2003.
-
(2003)
Diabetologia
, vol.46
, pp. 1465-1473
-
-
Schulze, M.B.1
Manson, J.E.2
Willett, W.C.3
Hu, F.B.4
-
45
-
-
19944369735
-
Adiponectin-mediated modulation of hypertrophic signals in the heart
-
Shibata R, Ouchi N, Ito M, Kihara S, Shiojima I, Pimentel DR, Kumada M, Sato K, Schiekofer S, Ohashi K, Funahashi T, Colucci WS, Walsh K. Adiponectin-mediated modulation of hypertrophic signals in the heart. Nat Med 10: 1384-1389, 2004.
-
(2004)
Nat Med
, vol.10
, pp. 1384-1389
-
-
Shibata, R.1
Ouchi, N.2
Ito, M.3
Kihara, S.4
Shiojima, I.5
Pimentel, D.R.6
Kumada, M.7
Sato, K.8
Schiekofer, S.9
Ohashi, K.10
Funahashi, T.11
Colucci, W.S.12
Walsh, K.13
-
46
-
-
24144446404
-
Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability
-
Tremblay F, Krebs M, Dombrowski L, Brehm A, Bernroider E, Roth E, Nowotny P, Waldhausl W, Marette A, Roden M. Overactivation of S6 kinase 1 as a cause of human insulin resistance during increased amino acid availability. Diabetes 54: 2674-2684, 2005.
-
(2005)
Diabetes
, vol.54
, pp. 2674-2684
-
-
Tremblay, F.1
Krebs, M.2
Dombrowski, L.3
Brehm, A.4
Bernroider, E.5
Roth, E.6
Nowotny, P.7
Waldhausl, W.8
Marette, A.9
Roden, M.10
-
47
-
-
33644886769
-
Nutrients suppress phosphatidylinositol 3-kinase/ Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation
-
Tzatsos A, Kandror KV. Nutrients suppress phosphatidylinositol 3-kinase/ Akt signaling via raptor-dependent mTOR-mediated insulin receptor substrate 1 phosphorylation. Mol Cell Biol 26: 63-76, 2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 63-76
-
-
Tzatsos, A.1
Kandror, K.V.2
-
48
-
-
0029117304
-
Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation
-
Wen Z, Zhong Z, Darnell JE Jr. Maximal activation of transcription by Stat1 and Stat3 requires both tyrosine and serine phosphorylation. Cell 82: 241-250, 1995.
-
(1995)
Cell
, vol.82
, pp. 241-250
-
-
Wen, Z.1
Zhong, Z.2
Darnell Jr., J.E.3
-
49
-
-
39449096289
-
Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metforminenhanced activation of the AMP-activated protein kinase in endothelial cells
-
Xie Z, Dong Y, Scholz R, Neumann D, Zou MH. Phosphorylation of LKB1 at serine 428 by protein kinase C-zeta is required for metforminenhanced activation of the AMP-activated protein kinase in endothelial cells. Circulation 117: 952-962, 2008.
-
(2008)
Circulation
, vol.117
, pp. 952-962
-
-
Xie, Z.1
Dong, Y.2
Scholz, R.3
Neumann, D.4
Zou, M.H.5
-
50
-
-
67650083087
-
Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis
-
Xie Z, Dong Y, Zhang J, Scholz R, Neumann D, Zou MH. Identification of the serine 307 of LKB1 as a novel phosphorylation site essential for its nucleocytoplasmic transport and endothelial cell angiogenesis. Mol Cell Biol 29: 3582-3596, 2009.
-
(2009)
Mol Cell Biol
, vol.29
, pp. 3582-3596
-
-
Xie, Z.1
Dong, Y.2
Zhang, J.3
Scholz, R.4
Neumann, D.5
Zou, M.H.6
-
51
-
-
80053393865
-
AMP-activated protein kinase modulates cardiac autophagy in diabetic cardiomyopathy
-
Xie Z, He C, Zou MH. AMP-activated protein kinase modulates cardiac autophagy in diabetic cardiomyopathy. Autophagy 7: 1254-1255, 2011.
-
(2011)
Autophagy
, vol.7
, pp. 1254-1255
-
-
Xie, Z.1
He, C.2
Zou, M.H.3
-
52
-
-
79959385996
-
Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice
-
Xie Z, Lau K, Eby B, Lozano P, He C, Pennington B, Li H, Rathi S, Dong Y, Tian R, Kem D, Zou MH. Improvement of cardiac functions by chronic metformin treatment is associated with enhanced cardiac autophagy in diabetic OVE26 mice. Diabetes 60: 1770-1778, 2011.
-
(2011)
Diabetes
, vol.60
, pp. 1770-1778
-
-
Xie, Z.1
Lau, K.2
Eby, B.3
Lozano, P.4
He, C.5
Pennington, B.6
Li, H.7
Rathi, S.8
Dong, Y.9
Tian, R.10
Kem, D.11
Zou, M.H.12
-
53
-
-
1542467581
-
Osteopontin inhibits interleukin-1beta-stimulated increases in matrix metalloproteinase activity in adult rat cardiac fibroblasts: Role of protein kinase C-zeta
-
Xie Z, Singh M, Siwik DA, Joyner WL, Singh K. Osteopontin inhibits interleukin-1beta-stimulated increases in matrix metalloproteinase activity in adult rat cardiac fibroblasts: role of protein kinase C-zeta. J Biol Chem 278: 48546-48552, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 48546-48552
-
-
Xie, Z.1
Singh, M.2
Siwik, D.A.3
Joyner, W.L.4
Singh, K.5
-
54
-
-
58149358854
-
Upregulation of mitochondrial uncoupling protein-2 by the AMP-activated protein kinase in endothelial cells attenuates oxidative stress in diabetes
-
Xie Z, Zhang J, Wu J, Viollet B, Zou MH. Upregulation of mitochondrial uncoupling protein-2 by the AMP-activated protein kinase in endothelial cells attenuates oxidative stress in diabetes. Diabetes 57: 3222-3230, 2008.
-
(2008)
Diabetes
, vol.57
, pp. 3222-3230
-
-
Xie, Z.1
Zhang, J.2
Wu, J.3
Viollet, B.4
Zou, M.H.5
-
55
-
-
33750040886
-
S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt
-
Zhang HH, Lipovsky AI, Dibble CC, Sahin M, Manning BD. S6K1 regulates GSK3 under conditions of mTOR-dependent feedback inhibition of Akt. Mol Cell 24: 185-197, 2006.
-
(2006)
Mol Cell
, vol.24
, pp. 185-197
-
-
Zhang, H.H.1
Lipovsky, A.I.2
Dibble, C.C.3
Sahin, M.4
Manning, B.D.5
-
56
-
-
0034773404
-
Role of AMP-activated protein kinase in mechanism of metformin action
-
Zhou G, Myers R, Li Y, Chen Y, Shen X, Fenyk-Melody J, Wu M, Ventre J, Doebber T, Fujii N, Musi N, Hirshman MF, Goodyear LJ, Moller DE. Role of AMP-activated protein kinase in mechanism of metformin action. J Clin Invest 108: 1167-1174, 2001.
-
(2001)
J Clin Invest
, vol.108
, pp. 1167-1174
-
-
Zhou, G.1
Myers, R.2
Li, Y.3
Chen, Y.4
Shen, X.5
Fenyk-Melody, J.6
Wu, M.7
Ventre, J.8
Doebber, T.9
Fujii, N.10
Musi, N.11
Hirshman, M.F.12
Goodyear, L.J.13
Moller, D.E.14
-
57
-
-
84876220612
-
Regulation of interplay between autophagy and apoptosis in the diabetic heart: New role of AMPK
-
Zou MH, Xie Z. Regulation of interplay between autophagy and apoptosis in the diabetic heart: new role of AMPK. Autophagy 9: 624-625, 2013.
-
(2013)
Autophagy
, vol.9
, pp. 624-625
-
-
Zou, M.H.1
Xie, Z.2
|