-
1
-
-
34250788809
-
-
Manning BD, Cantley LC. AKT/PKB signaling: navigating downstream. Cell. 2007;129(7):1261-1274.
-
Manning BD, Cantley LC. AKT/PKB signaling: navigating downstream. Cell. 2007;129(7):1261-1274.
-
-
-
-
2
-
-
33747819801
-
mTOR and cancer: Insights into a complex relationship
-
Sabatini DM. mTOR and cancer: insights into a complex relationship. Nat Rev Cancer. 2006;6(9):729-734.
-
(2006)
Nat Rev Cancer
, vol.6
, Issue.9
, pp. 729-734
-
-
Sabatini, D.M.1
-
3
-
-
0037178786
-
mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery
-
Kim DH, et al. mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery. Cell. 2002;110(2):163-175.
-
(2002)
Cell
, vol.110
, Issue.2
, pp. 163-175
-
-
Kim, D.H.1
-
4
-
-
0037178781
-
Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action
-
Hara K, et al. Raptor, a binding partner of target of rapamycin (TOR), mediates TOR action. Cell. 2002;110(2):177-189.
-
(2002)
Cell
, vol.110
, Issue.2
, pp. 177-189
-
-
Hara, K.1
-
5
-
-
0345167800
-
TSC2 mediates cellular energy response to control cell growth and survival
-
Inoki K, Zhu T, Guan KL. TSC2 mediates cellular energy response to control cell growth and survival. Cell. 2003;115(5):577-590.
-
(2003)
Cell
, vol.115
, Issue.5
, pp. 577-590
-
-
Inoki, K.1
Zhu, T.2
Guan, K.L.3
-
6
-
-
33646582664
-
Hypothalamic mTOR signaling regulates food intake
-
Cota D, et al. Hypothalamic mTOR signaling regulates food intake. Science. 2006;312(5775):927-930.
-
(2006)
Science
, vol.312
, Issue.5775
, pp. 927-930
-
-
Cota, D.1
-
7
-
-
27744569843
-
mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events
-
Holz MK, Ballif BA, Gygi SP, Blenis J. mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events. Cell. 2005;123(4):569-580.
-
(2005)
Cell
, vol.123
, Issue.4
, pp. 569-580
-
-
Holz, M.K.1
Ballif, B.A.2
Gygi, S.P.3
Blenis, J.4
-
8
-
-
45849105156
-
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
-
Sancak Y, et al. The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1. Science. 2008;320(5882):1496-1501.
-
(2008)
Science
, vol.320
, Issue.5882
, pp. 1496-1501
-
-
Sancak, Y.1
-
9
-
-
48649085816
-
Regulation of TORC1 by Rag GTPases in nutrient response
-
Kim E, Goraksha-Hicks P, Li L, Neufeld TP, Guan KL. Regulation of TORC1 by Rag GTPases in nutrient response. Nat Cell Biol. 2008;10(8):935-945.
-
(2008)
Nat Cell Biol
, vol.10
, Issue.8
, pp. 935-945
-
-
Kim, E.1
Goraksha-Hicks, P.2
Li, L.3
Neufeld, T.P.4
Guan, K.L.5
-
10
-
-
0036501277
-
A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells
-
Kwiatkowski DJ, et al. A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells. Hum Mol Genet. 2002;11(5):525-534.
-
(2002)
Hum Mol Genet
, vol.11
, Issue.5
, pp. 525-534
-
-
Kwiatkowski, D.J.1
-
11
-
-
0036714127
-
Akt regulates growth by directly phosphorylating Tsc2
-
Potter CJ, Pedraza LG, Xu T. Akt regulates growth by directly phosphorylating Tsc2. Nat Cell Biol. 2002;4(9):658-665.
-
(2002)
Nat Cell Biol
, vol.4
, Issue.9
, pp. 658-665
-
-
Potter, C.J.1
Pedraza, L.G.2
Xu, T.3
-
13
-
-
0036713778
-
TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling
-
Inoki K, Li Y, Zhu T, Wu J, Guan KL. TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling. Nat Cell Biol. 2002;4(9):648-657.
-
(2002)
Nat Cell Biol
, vol.4
, Issue.9
, pp. 648-657
-
-
Inoki, K.1
Li, Y.2
Zhu, T.3
Wu, J.4
Guan, K.L.5
-
15
-
-
8844250781
-
Aberrant cellular differentiation and migration in renal and pulmonary tuberous sclerosis complex
-
Astrinidis A, Henske EP. Aberrant cellular differentiation and migration in renal and pulmonary tuberous sclerosis complex. J Child Neurol. 2004;19(9):710-715.
-
(2004)
J Child Neurol
, vol.19
, Issue.9
, pp. 710-715
-
-
Astrinidis, A.1
Henske, E.P.2
-
16
-
-
0036943576
-
Tsc2 null murine neuroepithelial cells are a model for human tuber giant cells, and show activation of an mTOR pathway
-
Onda H, et al. Tsc2 null murine neuroepithelial cells are a model for human tuber giant cells, and show activation of an mTOR pathway. Mol Cell Neurosci. 2002;21(4):561-574.
-
(2002)
Mol Cell Neurosci
, vol.21
, Issue.4
, pp. 561-574
-
-
Onda, H.1
-
17
-
-
8644274532
-
The tuberous sclerosis complex genes in tumor development
-
Mak BC, Yeung RS. The tuberous sclerosis complex genes in tumor development. Cancer Invest. 2004;22(4):588-603.
-
(2004)
Cancer Invest
, vol.22
, Issue.4
, pp. 588-603
-
-
Mak, B.C.1
Yeung, R.S.2
-
18
-
-
40549088524
-
PLD regulates myoblast differentiation through the mTOR-IGF2 pathway
-
Yoon MS, Chen J. PLD regulates myoblast differentiation through the mTOR-IGF2 pathway. J Cell Sci. 2008;121(Pt 3):282-289.
-
(2008)
J Cell Sci
, vol.121
, Issue.PART 3
, pp. 282-289
-
-
Yoon, M.S.1
Chen, J.2
-
19
-
-
33645214765
-
PKBalpha is required for adipose differentiation of mouse embryonic fibroblasts
-
Baudry A, Yang ZZ, Hemmings BA. PKBalpha is required for adipose differentiation of mouse embryonic fibroblasts. J Cell Sci. 2006;119(Pt 5):889-897.
-
(2006)
J Cell Sci
, vol.119
, Issue.PART 5
, pp. 889-897
-
-
Baudry, A.1
Yang, Z.Z.2
Hemmings, B.A.3
-
20
-
-
67650074206
-
mTOR regulates memory CD8 T-cell differentiation
-
Araki K, et al. mTOR regulates memory CD8 T-cell differentiation. Nature. 2009;460(7251):108-112.
-
(2009)
Nature
, vol.460
, Issue.7251
, pp. 108-112
-
-
Araki, K.1
-
21
-
-
58049196780
-
mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization
-
Gan B, et al. mTORC1-dependent and -independent regulation of stem cell renewal, differentiation, and mobilization. Proc Natl Acad Sci U S A. 2008;105(49):19384-19389.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.49
, pp. 19384-19389
-
-
Gan, B.1
-
22
-
-
33845299568
-
-
Ehebauer M, Hayward P, Arias AM. Notch, a universal arbiter of cell fate decisions. Science. 2006;314(5804):1414-1415.
-
Ehebauer M, Hayward P, Arias AM. Notch, a universal arbiter of cell fate decisions. Science. 2006;314(5804):1414-1415.
-
-
-
-
23
-
-
53649091265
-
Notch signaling respecifies the hemangioblast to a cardiac fate
-
Chen VC, Stull R, Joo D, Cheng X, Keller G. Notch signaling respecifies the hemangioblast to a cardiac fate. Nat Biotechnol. 2008;26(10):1169- 1178.
-
(2008)
Nat Biotechnol
, vol.26
, Issue.10
, pp. 1169-1178
-
-
Chen, V.C.1
Stull, R.2
Joo, D.3
Cheng, X.4
Keller, G.5
-
24
-
-
0036117680
-
Multiple levels of Notch signal regulation (review)
-
Baron M, et al. Multiple levels of Notch signal regulation (review). Mol Membr Biol. 2002;19(1):27-38.
-
(2002)
Mol Membr Biol
, vol.19
, Issue.1
, pp. 27-38
-
-
Baron, M.1
-
25
-
-
1842452938
-
Dual roles for the Notch target gene Hes-1 in the differentiation of 3T3-L1 preadipocytes
-
Ross DA, Rao PK, Kadesch T. Dual roles for the Notch target gene Hes-1 in the differentiation of 3T3-L1 preadipocytes. Mol Cell Biol. 2004;24(8):3505-3513.
-
(2004)
Mol Cell Biol
, vol.24
, Issue.8
, pp. 3505-3513
-
-
Ross, D.A.1
Rao, P.K.2
Kadesch, T.3
-
26
-
-
33846236394
-
The multifaceted role of Notch in cancer
-
Roy M, Pear WS, Aster JC. The multifaceted role of Notch in cancer. Curr Opin Genet Dev. 2007;17(1):52-59.
-
(2007)
Curr Opin Genet Dev
, vol.17
, Issue.1
, pp. 52-59
-
-
Roy, M.1
Pear, W.S.2
Aster, J.C.3
-
27
-
-
51349169034
-
Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia
-
Chiang MY, et al. Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia. J Clin Invest. 2008;118(9):3181-3194.
-
(2008)
J Clin Invest
, vol.118
, Issue.9
, pp. 3181-3194
-
-
Chiang, M.Y.1
-
28
-
-
27144518462
-
Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells
-
Delaney C, et al. Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cells. Blood. 2005;106(8):2693-2699.
-
(2005)
Blood
, vol.106
, Issue.8
, pp. 2693-2699
-
-
Delaney, C.1
-
29
-
-
0037370310
-
Notch1 functions as a tumor suppressor in mouse skin
-
Nicolas M, et al. Notch1 functions as a tumor suppressor in mouse skin. Nat Genet. 2003;33(3):416-421.
-
(2003)
Nat Genet
, vol.33
, Issue.3
, pp. 416-421
-
-
Nicolas, M.1
-
30
-
-
50849104230
-
Notch tumor suppressor function
-
Dotto GP. Notch tumor suppressor function. Oncogene. 2008;27(38):5115-5123.
-
(2008)
Oncogene
, vol.27
, Issue.38
, pp. 5115-5123
-
-
Dotto, G.P.1
-
31
-
-
0347988005
-
Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR
-
Zhang H, et al. Loss of Tsc1/Tsc2 activates mTOR and disrupts PI3K-Akt signaling through downregulation of PDGFR. J Clin Invest. 2003;112(8):1223-1233.
-
(2003)
J Clin Invest
, vol.112
, Issue.8
, pp. 1223-1233
-
-
Zhang, H.1
-
32
-
-
33644992638
-
The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis
-
Shen H, et al. The Notch coactivator, MAML1, functions as a novel coactivator for MEF2C-mediated transcription and is required for normal myogenesis. Genes Dev. 2006;20(6):675-688.
-
(2006)
Genes Dev
, vol.20
, Issue.6
, pp. 675-688
-
-
Shen, H.1
-
33
-
-
0028641559
-
Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor
-
Tontonoz P, Hu E, Spiegelman BM. Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor. Cell. 1994;79(7):1147-1156.
-
(1994)
Cell
, vol.79
, Issue.7
, pp. 1147-1156
-
-
Tontonoz, P.1
Hu, E.2
Spiegelman, B.M.3
-
34
-
-
33847394119
-
PDGFRs are critical for PI3K/Akt activation and negatively regulated by mTOR
-
Zhang H, et al. PDGFRs are critical for PI3K/Akt activation and negatively regulated by mTOR. J Clin Invest. 2007;117(3):730-738.
-
(2007)
J Clin Invest
, vol.117
, Issue.3
, pp. 730-738
-
-
Zhang, H.1
-
35
-
-
67249142528
-
A hypomorphic allele of Tsc2 highlights the role of TSC1/TSC2 in signaling to AKT and models mild human TSC2 alleles
-
Pollizzi K, et al. A hypomorphic allele of Tsc2 highlights the role of TSC1/TSC2 in signaling to AKT and models mild human TSC2 alleles. Hum Mol Genet. 2009;18(13):2378-2387.
-
(2009)
Hum Mol Genet
, vol.18
, Issue.13
, pp. 2378-2387
-
-
Pollizzi, K.1
-
36
-
-
34547172596
-
A transforming mutation in the pleckstrin homology domain of AKT1 in cancer
-
Carpten JD, et al. A transforming mutation in the pleckstrin homology domain of AKT1 in cancer. Nature. 2007;448(7152):439-444.
-
(2007)
Nature
, vol.448
, Issue.7152
, pp. 439-444
-
-
Carpten, J.D.1
-
37
-
-
4944241544
-
JAGGED1 expression is associated with prostate cancer metastasis and recurrence
-
Santagata S, et al. JAGGED1 expression is associated with prostate cancer metastasis and recurrence. Cancer Res. 2004;64(19):6854-6857.
-
(2004)
Cancer Res
, vol.64
, Issue.19
, pp. 6854-6857
-
-
Santagata, S.1
-
38
-
-
64249172203
-
The canonical Notch signaling pathway: Unfolding the activation mechanism
-
Kopan R, Ilagan MX. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell. 2009;137(2):216-233.
-
(2009)
Cell
, vol.137
, Issue.2
, pp. 216-233
-
-
Kopan, R.1
Ilagan, M.X.2
-
39
-
-
2442436483
-
Consequences of Notchmediated induction of Jagged1
-
Ross DA, Kadesch T. Consequences of Notchmediated induction of Jagged1. Exp Cell Res. 2004;296(2):173-182.
-
(2004)
Exp Cell Res
, vol.296
, Issue.2
, pp. 173-182
-
-
Ross, D.A.1
Kadesch, T.2
-
40
-
-
18544384874
-
The p53 family member genes are involved in the Notch signal pathway
-
Sasaki Y, et al. The p53 family member genes are involved in the Notch signal pathway. J Biol Chem. 2002;277(1):719-724.
-
(2002)
J Biol Chem
, vol.277
, Issue.1
, pp. 719-724
-
-
Sasaki, Y.1
-
41
-
-
36048960476
-
p63 - Key molecule in the early phase of epithelial abnormality in idiopathic pulmonary f ibrosis
-
Murata K, et al. p63 - Key molecule in the early phase of epithelial abnormality in idiopathic pulmonary f ibrosis. Exp Mol Pathol. 2007;83(3):367-376.
-
(2007)
Exp Mol Pathol
, vol.83
, Issue.3
, pp. 367-376
-
-
Murata, K.1
-
42
-
-
33646711244
-
p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation
-
Laurikkala J, Mikkola ML, James M, Tummers M, Mills AA, Thesleff I. p63 regulates multiple signalling pathways required for ectodermal organogenesis and differentiation. Development. 2006;133(8):1553-1563.
-
(2006)
Development
, vol.133
, Issue.8
, pp. 1553-1563
-
-
Laurikkala, J.1
Mikkola, M.L.2
James, M.3
Tummers, M.4
Mills, A.A.5
Thesleff, I.6
-
43
-
-
0346435092
-
Delta Np63 alpha expression is regulated by the phosphoinositide 3-kinase pathway
-
Barbieri CE, Barton CE, Pietenpol JA. Delta Np63 alpha expression is regulated by the phosphoinositide 3-kinase pathway. J Biol Chem. 2003;278(51):51408-51414.
-
(2003)
J Biol Chem
, vol.278
, Issue.51
, pp. 51408-51414
-
-
Barbieri, C.E.1
Barton, C.E.2
Pietenpol, J.A.3
-
44
-
-
33646155964
-
TA-p63-gamma regulates expression of DeltaN-p63 in a manner that is sensitive to p53
-
Li N, Li H, Cherukuri P, Farzan S, Harmes DC, DiRenzo J. TA-p63-gamma regulates expression of DeltaN-p63 in a manner that is sensitive to p53. Oncogene. 2006;25(16):2349-2359.
-
(2006)
Oncogene
, vol.25
, Issue.16
, pp. 2349-2359
-
-
Li, N.1
Li, H.2
Cherukuri, P.3
Farzan, S.4
Harmes, D.C.5
DiRenzo, J.6
-
45
-
-
0034743628
-
p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes
-
Dohn M, Zhang S, Chen X. p63alpha and DeltaNp63alpha can induce cell cycle arrest and apoptosis and differentially regulate p53 target genes. Oncogene. 2001;20(25):3193-3205.
-
(2001)
Oncogene
, vol.20
, Issue.25
, pp. 3193-3205
-
-
Dohn, M.1
Zhang, S.2
Chen, X.3
-
46
-
-
0037507296
-
DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development
-
Wu G, et al. DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development. Cancer Res. 2003;63(10):2351-2357.
-
(2003)
Cancer Res
, vol.63
, Issue.10
, pp. 2351-2357
-
-
Wu, G.1
-
47
-
-
43149114238
-
Transcriptional activity of the DeltaNp63 promoter is regulated by STAT3
-
Chu WK, Dai PM, Li HL, Chen JK. Transcriptional activity of the DeltaNp63 promoter is regulated by STAT3. J Biol Chem. 2008;283(12):7328-7337.
-
(2008)
J Biol Chem
, vol.283
, Issue.12
, pp. 7328-7337
-
-
Chu, W.K.1
Dai, P.M.2
Li, H.L.3
Chen, J.K.4
-
48
-
-
0033968596
-
Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR
-
Yokogami K, Wakisaka S, Avruch J, Reeves SA. Serine phosphorylation and maximal activation of STAT3 during CNTF signaling is mediated by the rapamycin target mTOR. Curr Biol. 2000;10(1):47-50.
-
(2000)
Curr Biol
, vol.10
, Issue.1
, pp. 47-50
-
-
Yokogami, K.1
Wakisaka, S.2
Avruch, J.3
Reeves, S.A.4
-
49
-
-
2442648035
-
Perturbed IFN-gamma-Jaksignal transducers and activators of transcription signaling in tuberous sclerosis mouse models: Synergistic effects of rapamycin-IFN-gamma treatment
-
El-Hashemite N, Zhang H, Walker V, Hoffmeister KM, Kwiatkowski DJ. Perturbed IFN-gamma-Jaksignal transducers and activators of transcription signaling in tuberous sclerosis mouse models: synergistic effects of rapamycin-IFN-gamma treatment. Cancer Res. 2004;64(10):3436-3443.
-
(2004)
Cancer Res
, vol.64
, Issue.10
, pp. 3436-3443
-
-
El-Hashemite, N.1
Zhang, H.2
Walker, V.3
Hoffmeister, K.M.4
Kwiatkowski, D.J.5
-
50
-
-
38049146371
-
Diagnostic potential of serum VEGF-D for lymphangioleiomyomatosis
-
Young LR, Inoue Y, McCormack FX. Diagnostic potential of serum VEGF-D for lymphangioleiomyomatosis. N Engl J Med. 2008;358(2):199-200.
-
(2008)
N Engl J Med
, vol.358
, Issue.2
, pp. 199-200
-
-
Young, L.R.1
Inoue, Y.2
McCormack, F.X.3
-
51
-
-
55849139852
-
Notch1 is an effector of Akt and hypoxia in melanoma development
-
Bedogni B, Warneke JA, Nickoloff BJ, Giaccia AJ, Powell MB. Notch1 is an effector of Akt and hypoxia in melanoma development. J Clin Invest. 2008;118(11):3660-3670.
-
(2008)
J Clin Invest
, vol.118
, Issue.11
, pp. 3660-3670
-
-
Bedogni, B.1
Warneke, J.A.2
Nickoloff, B.J.3
Giaccia, A.J.4
Powell, M.B.5
-
52
-
-
0033577768
-
Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors
-
Bash J, et al. Rel/NF-kappaB can trigger the Notch signaling pathway by inducing the expression of Jagged1, a ligand for Notch receptors. EMBO J. 1999;18(10):2803-2811.
-
(1999)
EMBO J
, vol.18
, Issue.10
, pp. 2803-2811
-
-
Bash, J.1
-
53
-
-
0027359827
-
WAF1, a potential mediator of p53 tumor suppression
-
El-Deiry WS, et al. WAF1, a potential mediator of p53 tumor suppression. Cell. 1993;75(4):817-825.
-
(1993)
Cell
, vol.75
, Issue.4
, pp. 817-825
-
-
El-Deiry, W.S.1
-
54
-
-
0034079520
-
The p53/p63/p73 family of transcription factors: Overlapping and distinct functions
-
Levrero M, De Laurenzi V, Costanzo A, Gong J, Wang JY, Melino G. The p53/p63/p73 family of transcription factors: overlapping and distinct functions. J Cell Sci. 2000;113(Pt 10):1661-1670.
-
(2000)
J Cell Sci
, vol.113
, Issue.PART 10
, pp. 1661-1670
-
-
Levrero, M.1
De Laurenzi, V.2
Costanzo, A.3
Gong, J.4
Wang, J.Y.5
Melino, G.6
-
55
-
-
49049105552
-
Contribution of p53, p63, and p73 to the developmental diseases and cancer
-
Tomkova K, Tomka M, Zajac V. Contribution of p53, p63, and p73 to the developmental diseases and cancer. Neoplasma. 2008;55(3):177-181.
-
(2008)
Neoplasma
, vol.55
, Issue.3
, pp. 177-181
-
-
Tomkova, K.1
Tomka, M.2
Zajac, V.3
-
56
-
-
36549026878
-
Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53
-
Lee CH, et al. Constitutive mTOR activation in TSC mutants sensitizes cells to energy starvation and genomic damage via p53. EMBO J. 2007;26(23):4812-4823.
-
(2007)
EMBO J
, vol.26
, Issue.23
, pp. 4812-4823
-
-
Lee, C.H.1
-
57
-
-
58149478492
-
mTOR regulates autophagy-associated genes downstream of p73
-
Rosenbluth JM, Pietenpol JA. mTOR regulates autophagy-associated genes downstream of p73. Autophagy. 2009;5(1):114-116.
-
(2009)
Autophagy
, vol.5
, Issue.1
, pp. 114-116
-
-
Rosenbluth, J.M.1
Pietenpol, J.A.2
-
58
-
-
33847048245
-
The roles of p63 in cancer
-
Flores ER. The roles of p63 in cancer. Cell Cycle. 2007;6(3):300-304.
-
(2007)
Cell Cycle
, vol.6
, Issue.3
, pp. 300-304
-
-
Flores, E.R.1
-
59
-
-
34249304441
-
Mammalian target of rapamycin activation impairs hepatocytic differentiation and targets genes moderating lipid homeostasis and hepatocellular growth
-
Parent R, Kolippakkam D, Booth G, Beretta L. Mammalian target of rapamycin activation impairs hepatocytic differentiation and targets genes moderating lipid homeostasis and hepatocellular growth. Cancer Res. 2007;67(9):4337-4345.
-
(2007)
Cancer Res
, vol.67
, Issue.9
, pp. 4337-4345
-
-
Parent, R.1
Kolippakkam, D.2
Booth, G.3
Beretta, L.4
-
60
-
-
51349169034
-
Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia
-
Chiang MY, et al. Leukemia-associated NOTCH1 alleles are weak tumor initiators but accelerate K-ras-initiated leukemia. J Clin Invest. 2008;118(9):3181-3194.
-
(2008)
J Clin Invest
, vol.118
, Issue.9
, pp. 3181-3194
-
-
Chiang, M.Y.1
-
61
-
-
0042286558
-
Notch and cancer: Best to avoid the ups and downs
-
Maillard I, Pear WS. Notch and cancer: best to avoid the ups and downs. Cancer Cell. 2003;3(3):203-205.
-
(2003)
Cancer Cell
, vol.3
, Issue.3
, pp. 203-205
-
-
Maillard, I.1
Pear, W.S.2
-
62
-
-
38149015554
-
Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo
-
Sjolund J, et al. Suppression of renal cell carcinoma growth by inhibition of Notch signaling in vitro and in vivo. J Clin Invest. 2008;118(1):217-228.
-
(2008)
J Clin Invest
, vol.118
, Issue.1
, pp. 217-228
-
-
Sjolund, J.1
-
63
-
-
34347369749
-
Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia
-
Chan SM, Weng AP, Tibshirani R, Aster JC, Utz PJ. Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia. Blood. 2007;110(1):278-286.
-
(2007)
Blood
, vol.110
, Issue.1
, pp. 278-286
-
-
Chan, S.M.1
Weng, A.P.2
Tibshirani, R.3
Aster, J.C.4
Utz, P.J.5
-
64
-
-
41749121487
-
Reciprocal regulation of Notch and PI3K/Akt signalling in T-ALL cells in vitro
-
Calzavara E, et al. Reciprocal regulation of Notch and PI3K/Akt signalling in T-ALL cells in vitro. J Cell Biochem. 2008;103(5):1405- 1412.
-
(2008)
J Cell Biochem
, vol.103
, Issue.5
, pp. 1405-1412
-
-
Calzavara, E.1
-
65
-
-
0033662392
-
MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors
-
Wu L, et al. MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors. Nat Genet. 2000;26(4):484-489.
-
(2000)
Nat Genet
, vol.26
, Issue.4
, pp. 484-489
-
-
Wu, L.1
-
66
-
-
20244389684
-
Notch1 expression in early lymphopoiesis influences B versus T lineage determination
-
Pui JC, et al. Notch1 expression in early lymphopoiesis influences B versus T lineage determination. Immunity. 1999;11(3):299-308.
-
(1999)
Immunity
, vol.11
, Issue.3
, pp. 299-308
-
-
Pui, J.C.1
-
67
-
-
0035866350
-
Identification of CGA as a novel estrogen receptor-responsive gene in breast cancer: An outstanding candidate marker to predict the response to endocrine therapy
-
Bieche I, et al. Identification of CGA as a novel estrogen receptor-responsive gene in breast cancer: an outstanding candidate marker to predict the response to endocrine therapy. Cancer Res. 2001;61(4):1652-1658.
-
(2001)
Cancer Res
, vol.61
, Issue.4
, pp. 1652-1658
-
-
Bieche, I.1
|