Exploitation of auxotrophies and metabolic defects in Toxoplasma as therapeutic approaches

International Journal for Parasitology

Volumn 44, Issue 2, 2014, Pages 109-120

  Coppens, Isabelle ^a  

^a JOHNS HOPKINS BLOOMBERG SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

Apicomplexan parasites; Auxotrophy; Host cell adaptations; Inhibitors of transporters; Intracellular parasitism; Mechanisms of nutrient diversion; Salvage pathways; Toxoplasma

Indexed keywords

AMINO ACID; ARGININE; CHOLESTEROL; FOLIC ACID; POLYAMINE; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE; THIOCTIC ACID;

GENE; METABOLISM; METABOLITE; NUTRIENT; PARASITOLOGY; PROTIST;

AUXOTROPHY; CELL ADHESION; CELL MEMBRANE PERMEABILITY; CELL SIZE; CELL VACUOLE; ENDOCYTOSIS; GENOME ANALYSIS; HOST PARASITE INTERACTION; HUMAN; INTERNALIZATION; METABOLITE; MICROBIAL ACTIVITY; MICROBIAL METABOLISM; MOLECULAR EVOLUTION; NONHUMAN; PARASITE DEVELOPMENT; PARASITE VIRULENCE; REVIEW; SIGNAL TRANSDUCTION; TOXOPLASMA;

MAMMALIA; TOXOPLASMA; TOXOPLASMA GONDII;

APICOMPLEXAN PARASITES; AUXOTROPHY; HOST CELL ADAPTATIONS; INHIBITORS OF TRANSPORTERS; INTRACELLULAR PARASITISM; MECHANISMS OF NUTRIENT DIVERSION; SALVAGE PATHWAYS; TOXOPLASMA;

ANIMALS; ANTIPROTOZOAL AGENTS; HUMANS; TOXOPLASMA;

EID: 84892499849     PISSN: 00207519     EISSN: 18790135     Source Type: Journal    
DOI: 10.1016/j.ijpara.2013.09.003     Document Type: Review

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