Host-derived glucose and its transporter in the obligate intracellular pathogen Toxoplasma gondii are dispensable by glutaminolysis

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 31, 2009, Pages 12998-13003

  Blume, Martin ^a   Rodriguez Contreras, Dayana ^b   Landfear, Scott ^b   Fleige, Tobias ^c   Soldati Favre, Dominique ^c   Lucius, Richard ^a   Gupta, Nishith ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c UNIVERSITY OF GENEVA   (Switzerland)

Author keywords

Genetic manipulation; Glucose transport; Glutamine metabolism

Indexed keywords

FRUCTOSE; GALACTOSE; GLUCOSE TRANSPORTER; GLUTAMINE; MANNOSE; TOXOPLASMA GONDII GLUCOSE TRANSPORTER 1; TOXOPLASMA GONDII SUGAR TRANSPORTER 1; TOXOPLASMA GONDII SUGAR TRANSPORTER 2; TOXOPLASMA GONDII SUGAR TRANSPORTER 3; UNCLASSIFIED DRUG; GLUCOSE; GLUCOSE TRANSPORTER 1;

ANIMAL EXPERIMENT; ARTICLE; CELL MEMBRANE; GENE DELETION; GLUTAMINOLYSIS; GLYCOLYSIS; IN VIVO STUDY; MOUSE; NONHUMAN; PARASITE; PARASITE VIRULENCE; PHENOTYPE; PRIORITY JOURNAL; SUGAR TRANSPORT; TACHYZOITE; TOXOPLASMA GONDII; ANIMAL; CELL CULTURE; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PHYSIOLOGY; TOXOPLASMA;

MAMMALIA; MUS; TOXOPLASMA; TOXOPLASMA GONDII;

ANIMALS; BASE SEQUENCE; CELLS, CULTURED; GLUCOSE; GLUCOSE TRANSPORT PROTEINS, FACILITATIVE; GLUCOSE TRANSPORTER TYPE 1; GLUTAMINE; MANNOSE; MOLECULAR SEQUENCE DATA; TOXOPLASMA;

EID: 68049135099     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0903831106     Document Type: Article

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