Heterologous expression and characterization of the bifunctional dihydrofolate reductase-thymidylate synthase enzyme of Toxoplasma gondii

Biochemistry

Volumn 35, Issue 20, 1996, Pages 6366-6374

  Trujillo, Mónica ^a   Donald, Robert G K ^b   Roos, David S ^b   Greene, Patricia J ^a   Santi, Daniel V ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROFOLATE REDUCTASE; PYRIMETHAMINE; THYMIDINE PHOSPHATE; THYMIDYLATE SYNTHASE;

ARTICLE; CONTROLLED STUDY; ENZYME CHEMISTRY; ENZYME CONFORMATION; ENZYME MECHANISM; FOLATE METABOLISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING; PYRIMIDINE SYNTHESIS; TOXOPLASMA GONDII;

ANIMALS; BASE SEQUENCE; CLONING, MOLECULAR; DNA PRIMERS; DNA, PROTOZOAN; ESCHERICHIA COLI; FOLIC ACID ANTAGONISTS; GENE EXPRESSION; GENETIC VECTORS; KINETICS; MOLECULAR SEQUENCE DATA; MULTIENZYME COMPLEXES; PYRIMETHAMINE; RECOMBINANT PROTEINS; TETRAHYDROFOLATE DEHYDROGENASE; THYMIDYLATE SYNTHASE; TOXOPLASMA; TRIMETHOPRIM;

EID: 0029886547     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi952923q     Document Type: Article

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