Host cell P-glycoprotein is essential for cholesterol uptake and replication of Toxoplasma gondii

Journal of Biological Chemistry

Volumn 284, Issue 26, 2009, Pages 17438-17448

  Bottova, Iveta ^a   Hehl, Adrian B ^a   Štefanić, Saša ^a   Fabriás, Gemma ^b   Casas, Josefina ^b   Schraner, Elisabeth ^a   Pieters, Jean ^c   Sonda, Sabrina ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b INSTITUTE OF ADVANCED CHEMISTRY OF CATALONIA IQAC CSIC   (Spain)

^c UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL CONTENT; CHOLESTEROL METABOLISM; EFFLUX PUMPS; HOST CELLS; INTRACELLULAR PARASITES; MAMMALIAN CELLS; MEMBRANE-BOUND; MULTIDRUG RESISTANCE; P-GLYCOPROTEIN; PARASITE-; PHYSIOLOGICAL PROCESS; SPHINGOLIPID METABOLISM; TOXOPLASMA GONDII;

BIOCHEMISTRY; CELL CULTURE; CHOLESTEROL; FIBROBLASTS; GLYCOPROTEINS; INTERNATIONAL TRADE; MAMMALS; METABOLISM;

CELL MEMBRANES;

CHOLESTEROL; GLYCOPROTEIN P; SPHINGOLIPID;

ANIMAL CELL; ARTICLE; CELL INVASION; CHOLESTEROL METABOLISM; CHOLESTEROL TRANSPORT; CONTROLLED STUDY; EMBRYO; FIBROBLAST; GENE REPLICATION; HOST CELL; HOST PARASITE INTERACTION; HUMAN; HUMAN CELL; LIPID METABOLISM; MAMMAL CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TOXOPLASMA GONDII;

ANIMALS; BIOLOGICAL TRANSPORT; BLOTTING, WESTERN; CELLS, CULTURED; CHOLESTEROL; CHROMATOGRAPHY, LIQUID; EMBRYO, MAMMALIAN; FIBROBLASTS; FLUORESCENT ANTIBODY TECHNIQUE; HOST-PARASITE INTERACTIONS; LIPIDS; MASS SPECTROMETRY; MICE; MICE, KNOCKOUT; NEOSPORA; NIH 3T3 CELLS; P-GLYCOPROTEINS; TOXOPLASMA;

MAMMALIA; TOXOPLASMA GONDII;

EID: 67650531128     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M809420200     Document Type: Article

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