Interaction between parasitophorous vacuolar membrane-associated GRA3 and calcium modulating ligand of host cell endoplasmic reticulum in the parasitism of toxoplasma gondii

Korean Journal of Parasitology

Volumn 46, Issue 4, 2008, Pages 209-216

  Kim, Ji Yeon ^a   Ahn, Hye Jin ^a   Ryu, Kyung Ju ^a   Nam, Ho Woo ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

CAMLG; CDNA sequence; GRA3; PVM ER interaction; Toxoplasma gondii; Yeast two hybrid

Indexed keywords

CALCIUM MODULATING LIGAND; GLUTATHIONE TRANSFERASE; MEMBRANE PROTEIN; PLASMID DNA; PROTEIN GRA3; UNCLASSIFIED DRUG; CAMLG PROTEIN, HUMAN; GRA3 PROTEIN, TOXOPLASMA GONDII; PROTOZOAL PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOPLASM; DNA LIBRARY; DNA SEQUENCE; ENDOPLASMIC RETICULUM; ENZYME ASSAY; HELA CELL; HOST CELL; HOST PATHOGEN INTERACTION; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; LIGAND BINDING; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PARASITISM; PARASITOPHOROUS VACUOLAR MEMBRANE; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MOTIF; SEQUENCE HOMOLOGY; TACHYZOITE; TONOPLAST; TOXOPLASMA GONDII; TRANSMEMBRANE DOMAIN; TWO HYBRID SYSTEM; ANIMAL; CHEMISTRY; GENETICS; HOST PARASITE INTERACTION; METABOLISM; MOLECULAR GENETICS; PARASITOLOGY; PHYSIOLOGY; TOXOPLASMA; TOXOPLASMOSIS;

POTATO VIRUS M; TOXOPLASMA GONDII;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; ENDOPLASMIC RETICULUM; HELA CELLS; HOST-PARASITE INTERACTIONS; HUMANS; MOLECULAR SEQUENCE DATA; PROTOZOAN PROTEINS; TOXOPLASMA; TOXOPLASMOSIS;

EID: 63149118743     PISSN: 00234001     EISSN: 17380006     Source Type: Journal    
DOI: 10.3347/kjp.2008.46.4.209     Document Type: Article

References (35)

1. Choi WY, Nam HW, Kwak NH, Huh W, Kim YR, Kang MW, Cho SY, Dubey JP. Foodborne outbreaks of human toxoplasmosis. J Infect Dis 1997; 175: 1280-1282.
2. Magno RC, Straker LC, de Souza W, Attias M. Interrelations between the parasitophorous vacuole of Toxoplasma gondii and host cell organelles. Microsc Microanal 2005; 11: 166-174.
3. Morisaki JH, Heuser JE, Sibley LD. Invasion of Toxoplasma gondii occurs by active penetration of the host cells. J Cell Sci 1995; 108: 2457-2464.
4. Mordue DG, Hakansson S, Niesman I, Sibley LD. Toxoplasma gondii resides in a vacuole that avoids fusion with host cell endocytic and exocytic vesicular trafficking pathways. Exp Parasitol 1999; 92: 87-99.
5. Martin AM, Liu T, Lynn BC, Sainai AP. The Toxoplasma gondii parasitophorous vacuole membrane: transactions across the border. J Eukaryotic Microbiol 2007; 54: 25-28.
6. Dluzewski AR, Fryer PR, Griffiths S, Wilson RJ, Gratzer WB. Red cell membrane protein distribution during malarial invasion. J Cell Sci 1989; 92: 691-699.
7. Ward GE, Miller LH, Dvorak JA. The origin of parasitophorous vacuole membrane lipids in malaria-infected erythrocytes. J Cell Sci 1993; 106: 237-248.
8. Suss-Toby E, Zimmerberg J, Ward GE. Toxoplasma invasion: the parasitophorous vacuole is formed from host cell plasma membrane and pinches off via a fission pore. Proc Natl Acad Sci USA 1996; 93: 8413-8418.
9. Crawford MJ, Thomsen-Zieger N, Ray M, Schachtner J, Roos DS, Seeber F. Toxoplasma gondii scavenges host-derived lipoic acid despite its de novo synthesis in the apicoplast. EMBO J 2006; 25: 3214-3222.
10. Gupta N, Zahn MM, Coppens I, Joiner KA, Voelker DR. Selective disruption of phosphatidylcholine metabolism of the intracellular parasite Toxoplasma gondii arrests its growth. J Biol Chem 2005; 280: 16345-16353.
11. Coppens I. Contribution of host lipids to Toxoplasma pathogenesis. Cell Microbiol 2006; 8: 1-9.
12. Coppens I, Dunn JD, Romano JD, PypaertM, Zhang H, Boothroyd JC, Joiner KA. Toxoplasma gondii sequesters lysosomes from mammalian hosts in the vacuolar space. Cell 2006; 125: 261-274.
13. Sinai AP, Joiner KA. The Toxoplasma gondii protein ROP2 mediates host organelle association with the parasitophorous vacuole membrane. J Cell Biol 2001; 154: 95-108.
14. Son ES, Nam HW. Detection and characterization of excretory/secretory proteins from Toxoplasma gondii by monoclonal antibodies. Korean J Parasitol 2001; 39: 49-56.
15. Henriquez FL, Nickdel MB, McLeod R, Lyons RE, Lyons K, Dubremetz JF, Grigg ME, Samuel BU, Roberts CW. Toxoplasma gondii dense granule protein 3 (GRA3) is a type I transmembrane protein that possesses a cytoplasmic dilysine (KKXX) endoplasmic reticulum (ER) retrieval motif. Parasitology 2005; 131: 169-179.
16. Bermudes D, Dubremetz JF, Achbrou A, Joiner KA. Cloning of a cDNA encoding the dense granule protein GRA3 from Toxoplasma gondii. Mol Biochem Parasitol 1994; 68: 247-257.
17. Ahn HJ, Kim S, Kim HE, Nam HW. Interactions between secreted GRA proteins and host cell proteins across the parasitophorous vacuolar membrane in the parasitism of Toxoplasma gondii. Korean J Parasitol 2006; 44: 303-312.
18. Sohn WM, Nam HW. Western blot analysis of stray cat sera against Toxoplasma gondii and the diagnostic availability of monoclonal antibodies in sandwich-ELISA. Korean J Parasitol 1999; 37: 249-256.
19. Ahn HJ, Kim S, Nam HW. Host cell binding of GRA10, a novel, constitutively secreted dense granular protein from Toxoplasma gondii. Biochem Biophys Res Comm 2005; 331: 614-620.
20. Frohman MA, Dush MK, Martin GR. Rapid production of full-length cDNAs from rare transcripts: amplification using a single gene-specific oligonucleotide primer. Proc Natl Acad Sci USA 1988; 85: 8998-9002.
21. Fan Q, An L, Cui L. Plasmodium falciparum histone acetyltransferase, a yeast GCN5 homologue involved in chromatin remodeling. Eukaryotic Cell 2004; 3: 264-276.
22. Saharinen P, Takaluoma K, Silvennoinen O. Regulation of the Jak2 tyrosine kinase by its pseudokinase domain. Mol Cell Biol 2000; 20: 3387-3395.
23. Hoeck J, Woisetschlager M. Activation of Eotaxin-3/CCL26 gene expression in human dermal fibroblasts is mediated by STAT6. J Immunol 2001; 167: 3216-3222.
24. Seeber, F. Consensus sequence of translational initiation sites from Toxoplasma gondii. Parasitol Res 1997; 83: 309-311.
25. Bendtsen JD, Nielsen H, von Heijne G, Brunak S. Improved prediction of signal peptides: SignalP 3.0. J Mol Biol 2004; 340: 783-795.
26. Spiess M, Lodish HF. An internal signal sequence: the asialoglycoprotein receptor membrane anchor. Cell 1986; 44: 177-185.
27. Do H, Falcone D, Lin J, Andrews DW, Johnson AE. The cotranslational integration of membrane proteins into the phospholipids bilayer is a multistep process. Cell 1996; 85: 369-378.
28. Lecordier L, Moleon-Borodowsky I, Dubremetz, JF, Tourvieille B, Mercier C, Deslee D, Capron A, Cesbron-Delauw MF. Characterization of a dense granule antigen of Toxoplasma gondii (GRA6) associated to the network of the parasitophorous vacuole. Mol Biochem Parasitol 1995; 70: 85-94.
29. Mercier C, Adjogble KDZ, Daubener W, Cesbron-Delauw MF. Dense granule: are they key organelles to help understand the parasitophorous vacuole of all apicomplexa parasites? Int J Parasitol 2005; 35: 829-849.
30. Fischer HG, Stachelhaus S, Sahm M, Meyer HE, Reichmann G. GRA7, an excretory 29 kDa Toxoplasma gondii dense granule antigen released by infected host cells. Mol Biochem Parasitol 1998; 91: 251-262.
31. Bonifacino JS, Traub LM. Signals for sorting of transmembrane proteins to endosomes and lysosomes. Annu Rev Biochem 2003; 72: 395-447.
32. Hoppe HC, Ngo HM, Yang M, Joiner KA. Targeting to rhoptry organelles of Toxoplasma gondii involves evolutionarily conserved mechanisms. Nature Cell Biol 2000; 2: 449-456.
33. Hoppe HC, Joiner KA. Cytoplasmic tail motifs mediate endoplasmic reticulum localization and export of transmembrane reporters in the protozoan parasite Toxoplasma gondii. Cell Microbiol 2000; 2: 569-578.
34. Bram RJ, Crabtree GR. Calcium signaling in T cells stimulated by a cyclophilin B-binding protein. Nature 1994; 371: 355-358.
35. Holloway MP, Bram RJ. Co-localization of calcium-modulating cyclophilin ligand with intracellular calcium pools. J Biol Chem 1998; 273: 16346-16350.