-
1
-
-
73749083481
-
Global estimates of the prevalence of diabetes for 2010 and 2030
-
doi:10.1016/j.diabres.2009.10.007. PubMed: 19896746
-
Shaw JE, Sicree RA, Zimmet PZ (2010) Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 87:4-14. doi:10.1016/j.diabres.2009.10.007. PubMed: 19896746.
-
(2010)
Diabetes Res Clin Pract
, vol.87
, pp. 4-14
-
-
Shaw, J.E.1
Sicree, R.A.2
Zimmet, P.Z.3
-
2
-
-
79959936188
-
National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: Systematic analysis of health examination surveys and epidemiological studies with 370 countryyears and 2.7 million participants
-
doi:10.1016/S0140-6736 11 60679-X. PubMed: 21705069
-
Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ et al. (2011) National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 countryyears and 2.7 million participants. Lancet 378:31-40. doi:10.1016/S0140-6736 (11) 60679-X. PubMed: 21705069.
-
(2011)
Lancet
, vol.378
, pp. 31-40
-
-
Danaei, G.1
Finucane, M.M.2
Lu, Y.3
Singh, G.M.4
Cowan, M.J.5
-
3
-
-
0031851293
-
Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: Diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation
-
DOI 10.1002/(SICI)1096-9136(199807)15:7 <539::AID-DIA668>3.0.CO;2-S
-
Alberti KG, Zimmet PZ (1998) Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus provisional report of a WHO consultation. Diabet Med 15:539-553. doi:10.1002/(SICI) 1096-9136 (199807) 15:7. PubMed: 9686693. (Pubitemid 28319935)
-
(1998)
Diabetic Medicine
, vol.15
, Issue.7
, pp. 539-553
-
-
Alberti, K.G.M.M.1
Zimmet, P.Z.2
-
4
-
-
9444242665
-
Five of stages of evolving β-cell dysfunction during progression to diabetes
-
DOI 10.2337/diabetes.53.suppl-3.S16
-
Weir GC, Bonner-Weir S (2004) Five stages of evolving beta-cell dysfunction during progression to diabetes. Diabetes 53 Suppl 3:S16-S21. doi:10.2337/diabetes.53.suppl-3. S16. PubMed: 15561905. (Pubitemid 39564517)
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL. 3
-
-
Weir, G.C.1
Bonner-Weir, S.2
-
5
-
-
33845881411
-
Mechanisms linking obesity to insulin resistance and type 2 diabetes
-
DOI 10.1038/nature05482, PII NATURE05482
-
Kahn SE, Hull RL, Utzschneider KM (2006) Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444:840-846. doi: 10.1038/nature05482. PubMed: 17167471. (Pubitemid 46024990)
-
(2006)
Nature
, vol.444
, Issue.7121
, pp. 840-846
-
-
Kahn, S.E.1
Hull, R.L.2
Utzschneider, K.M.3
-
6
-
-
0037219411
-
β-cell deficit and increased β-cell apoptosis in humans with type 2 diabetes
-
DOI 10.2337/diabetes.52.1.102
-
Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA et al. (2003) Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 52:102-110. doi:10.2337/diabetes.52.1.102. PubMed: 12502499. (Pubitemid 36042113)
-
(2003)
Diabetes
, vol.52
, Issue.1
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
7
-
-
77950290798
-
{beta}-Cell mass dynamics and islet cell plasticity in human type 2 diabetes
-
doi:10.1210/en. 2009-1277. PubMed: 20176718
-
Hanley SC, Austin E, Assouline-Thomas B, Kapeluto J, Blaichman J et al. (2010) {beta}-Cell mass dynamics and islet cell plasticity in human type 2 diabetes. Endocrinology 151:1462-1472. doi:10.1210/en. 2009-1277. PubMed: 20176718.
-
(2010)
Endocrinology
, vol.151
, pp. 1462-1472
-
-
Hanley, S.C.1
Austin, E.2
Assouline-Thomas, B.3
Kapeluto, J.4
Blaichman, J.5
-
8
-
-
53549093011
-
Pancreatic beta-cell mass in European subjects with type 2 diabetes
-
doi:10.1111/j. 1463-1326.2008.00969.x. PubMed: 18834431
-
Rahier J, Guiot Y, Goebbels RM, Sempoux C, Henquin JC (2008) Pancreatic beta-cell mass in European subjects with type 2 diabetes. Diabetes Obes Metab 10 Suppl 4:32-42. doi:10.1111/j. 1463-1326.2008.00969.x. PubMed: 18834431.
-
(2008)
Diabetes Obes Metab
, vol.10
, Issue.SUPPL. 4
, pp. 32-42
-
-
Rahier, J.1
Guiot, Y.2
Goebbels, R.M.3
Sempoux, C.4
Henquin, J.C.5
-
9
-
-
0035122488
-
Endocrine pancreas plasticity under physiological and pathological conditions
-
Bernard-Kargar C, Ktorza A (2001) Endocrine pancreas plasticity under physiological and pathological conditions. Diabetes 50 Suppl 1:S30-S35. doi:10.2337/diabetes.50.2007. S30. PubMed: 11272194. (Pubitemid 32148212)
-
(2001)
Diabetes
, vol.50
, Issue.SUPPL. 1
-
-
Bernard-Kargar, C.1
Ktorza, A.2
-
10
-
-
12944320856
-
Pancreatic beta cell senescence contributes to the pathogenesis of type 2 diabetes in high-fat diet-induced diabetic mice
-
DOI 10.1007/s00125-004-1605-2
-
Sone H, Kagawa Y (2005) Pancreatic beta cell senescence contributes to the pathogenesis of type 2 diabetes in high-fat diet-induced diabetic mice. Diabetologia 48:58-67. doi:10.1007/s00125-004-1605-2. PubMed: 15624098. (Pubitemid 40174657)
-
(2005)
Diabetologia
, vol.48
, Issue.1
, pp. 58-67
-
-
Sone, H.1
Kagawa, Y.2
-
11
-
-
0024508097
-
Compensatory growth of pancreatic β-cells in adult rats after short-term glucose infusion
-
Bonner-Weir S, Deery D, Leahy JL, Weir GC (1989) Compensatory growth of pancreatic beta-cells in adult rats after short-term glucose infusion. Diabetes 38:49-53. doi:10.2337/diabetes.38.1.49. PubMed: 2642434. (Pubitemid 19021816)
-
(1989)
Diabetes
, vol.38
, Issue.1
, pp. 49-53
-
-
Bonner-Weir, S.1
Deery, D.2
Leahy, J.L.3
Weir, G.C.4
-
12
-
-
53549083761
-
Anatomical versus functional beta-cell mass in experimental diabetes
-
doi: 10.1111/j.1463-1326.2008.00886.x. PubMed: 18834432
-
Kargar C, Ktorza A (2008) Anatomical versus functional beta-cell mass in experimental diabetes. Diabetes Obes Metab 10 Suppl 4:43-53. doi: 10.1111/j.1463-1326.2008.00886.x. PubMed: 18834432.
-
(2008)
Diabetes Obes Metab
, vol.10
, Issue.SUPPL. 4
, pp. 43-53
-
-
Kargar, C.1
Ktorza, A.2
-
13
-
-
43549108142
-
Glucolipotoxicity: Fuel excess and β-cell dysfunction
-
DOI 10.1210/er.2007-0023
-
Poitout V, Robertson RP (2008) Glucolipotoxicity: fuel excess and betacell dysfunction. Endocr Rev 29:351-366. PubMed: 18048763. (Pubitemid 351679704)
-
(2008)
Endocrine Reviews
, vol.29
, Issue.3
, pp. 351-366
-
-
Poitout, V.1
Robertson, R.P.2
-
14
-
-
0029073613
-
Weight-reducing effects of the plasma protein encoded by the obese gene
-
doi:10.1126/science.7624777. PubMed: 7624777
-
Halaas JL, Gajiwala KS, Maffei M, Cohen SL, Chait BT et al. (1995) Weight-reducing effects of the plasma protein encoded by the obese gene. Science 269:543-546. doi:10.1126/science.7624777. PubMed: 7624777.
-
(1995)
Science
, vol.269
, pp. 543-546
-
-
Halaas, J.L.1
Gajiwala, K.S.2
Maffei, M.3
Cohen, S.L.4
Chait, B.T.5
-
15
-
-
0030039272
-
Abnormal splicing of the leptin receptor in diabetic mice
-
DOI 10.1038/379632a0
-
Lee GH, Proenca R, Montez JM, Carroll KM, Darvishzadeh JG et al. (1996) Abnormal splicing of the leptin receptor in diabetic mice. Nature 379:632-635. doi:10.1038/379632a0. PubMed: 8628397. (Pubitemid 26053452)
-
(1996)
Nature
, vol.379
, Issue.6566
, pp. 632-635
-
-
Lee, G.-H.1
Proenca, R.2
Montez, J.M.3
Carroll, K.M.4
Darvishzadeh, J.G.5
Lee, J.I.6
Friedman, J.M.7
-
16
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
DOI 10.1016/S0092-8674(00)81294-5
-
Chen H, Charlat O, Tartaglia LA, Woolf EA, Weng X et al. (1996) Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice. Cell 84:491-495. doi:10.1016/S0092-8674 (00) 81294-5. PubMed: 8608603. (Pubitemid 26060722)
-
(1996)
Cell
, vol.84
, Issue.3
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
Lakey, N.D.7
Culpepper, J.8
More, K.J.9
Breitbart, R.E.10
Duyk, G.M.11
Tepper, R.I.12
Morgenstern, J.P.13
-
17
-
-
0018139377
-
Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice
-
Coleman DL (1978) Obese and diabetes: two mutant genes causing diabetes-obesity syndromes in mice. Diabetologia 14:141-148. doi: 10.1007/BF00429772. PubMed: 350680. (Pubitemid 8286141)
-
(1978)
Diabetologia
, vol.14
, Issue.3
, pp. 141-148
-
-
Coleman, D.L.1
-
18
-
-
0014004384
-
Diabetes, a new mutation in the mouse
-
doi:10.1126/science. 153.3740.1127. PubMed: 5918576
-
Hummel KP, Dickie MM, Coleman DL (1966) Diabetes, a new mutation in the mouse. Science 153:1127-1128. doi:10.1126/science. 153.3740.1127. PubMed: 5918576.
-
(1966)
Science
, vol.153
, pp. 1127-1128
-
-
Hummel, K.P.1
Dickie, M.M.2
Coleman, D.L.3
-
19
-
-
0014076277
-
Studies with the mutation, diabetes, in the mouse
-
doi:10.1007/BF01222201. PubMed: 4907142
-
Coleman DL, Hummel KP (1967) Studies with the mutation, diabetes, in the mouse. Diabetologia 3:238-248. doi:10.1007/BF01222201. PubMed: 4907142.
-
(1967)
Diabetologia
, vol.3
, pp. 238-248
-
-
Coleman, D.L.1
Hummel, K.P.2
-
20
-
-
0014807533
-
The influence of age and dietary conditions on diabetes in the db mouse
-
doi:10.1007/BF01212237. PubMed: 4914664
-
Wyse BM, Dulin WE (1970) The influence of age and dietary conditions on diabetes in the db mouse. Diabetologia 6:268-273. doi:10.1007/BF01212237. PubMed: 4914664.
-
(1970)
Diabetologia
, vol.6
, pp. 268-273
-
-
Wyse, B.M.1
Dulin, W.E.2
-
21
-
-
0014805928
-
Studies in the diabetic mutant mouse. I. Light microscopy and radioautography of pancreatic islets
-
doi:10.1007/BF01212231. PubMed: 4914661
-
Like AA, Chick WL (1970) Studies in the diabetic mutant mouse. I. Light microscopy and radioautography of pancreatic islets. Diabetologia 6:207-215. doi:10.1007/BF01212231. PubMed: 4914661.
-
(1970)
Diabetologia
, vol.6
, pp. 207-215
-
-
Like, A.A.1
Chick, W.L.2
-
22
-
-
79955685810
-
Reduced proliferation and a high apoptotic frequency of pancreatic beta cells contribute to genetically-determined diabetes susceptibility of db/db BKS mice
-
doi:10.1055/s-0031-1271817. PubMed: 21412687
-
Puff R, Dames P, Weise M, Göke B, Seissler J et al. (2011) Reduced proliferation and a high apoptotic frequency of pancreatic beta cells contribute to genetically-determined diabetes susceptibility of db/db BKS mice. Horm Metab Res 43:306-311. doi:10.1055/s-0031-1271817. PubMed: 21412687.
-
(2011)
Horm Metab Res
, vol.43
, pp. 306-311
-
-
Puff, R.1
Dames, P.2
Weise, M.3
Göke, B.4
Seissler, J.5
-
23
-
-
13844262626
-
Structural and functional analysis of pancreatic islets preserved by pioglitazone in db/db mice
-
DOI 10.1152/ajpendo.00128.2004
-
Kawasaki F, Matsuda M, Kanda Y, Inoue H, Kaku K (2005) Structural and functional analysis of pancreatic islets preserved by pioglitazone in db/db mice. Am J Physiol Endocrinol Metab 288:E510-E518. PubMed: 15522998. (Pubitemid 40250545)
-
(2005)
American Journal of Physiology - Endocrinology and Metabolism
, vol.288
, Issue.3
-
-
Kawasaki, F.1
Matsuda, M.2
Kanda, Y.3
Inoue, H.4
Kaku, K.5
-
24
-
-
79954631160
-
The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes
-
doi:10.1007/s00125-011-2069-9. PubMed: 21340625
-
Shimoda M, Kanda Y, Hamamoto S, Tawaramoto K, Hashiramoto M et al. (2011) The human glucagon-like peptide-1 analogue liraglutide preserves pancreatic beta cells via regulation of cell kinetics and suppression of oxidative and endoplasmic reticulum stress in a mouse model of diabetes. Diabetologia 54:1098-1108. doi:10.1007/s00125-011-2069-9. PubMed: 21340625.
-
(2011)
Diabetologia
, vol.54
, pp. 1098-1108
-
-
Shimoda, M.1
Kanda, Y.2
Hamamoto, S.3
Tawaramoto, K.4
Hashiramoto, M.5
-
25
-
-
84871169665
-
The novel GLP-1-gastrin dual agonist, ZP3022, increases beta-cell mass and prevents diabetes in db/db mice
-
doi:10.1111/j.1463-1326.2012.01676.x. PubMed: 22862961
-
Fosgerau K, Jessen L, Lind Tolborg J, Østerlund T, Schaeffer Larsen K et al. (2013) The novel GLP-1-gastrin dual agonist, ZP3022, increases beta-cell mass and prevents diabetes in db/db mice. Diabetes Obes Metab 15:62-71. doi:10.1111/j.1463-1326.2012.01676.x. PubMed: 22862961.
-
(2013)
Diabetes Obes Metab
, vol.15
, pp. 62-71
-
-
Fosgerau, K.1
Jessen, L.2
Tolborg, J.L.3
Østerlund, T.4
Larsen, K.S.5
-
26
-
-
84863129902
-
FTY720 normalizes hyperglycemia by stimulating beta-cell in vivo regeneration in db/db mice through regulation of cyclin D3 and p57 (KIP2)
-
doi:10.1074/jbc. M111.305359. PubMed: 22194608
-
Zhao Z, Choi J, Zhao C, Ma ZA (2012) FTY720 normalizes hyperglycemia by stimulating beta-cell in vivo regeneration in db/db mice through regulation of cyclin D3 and p57 (KIP2). J Biol Chem 287:5562-5573. doi:10.1074/jbc. M111.305359. PubMed: 22194608.
-
(2012)
J Biol Chem
, vol.287
, pp. 5562-5573
-
-
Zhao, Z.1
Choi, J.2
Zhao, C.3
Ma, Z.A.4
-
27
-
-
78649418117
-
Stereological assessment of pancreatic beta-cell mass development in male Zucker Diabetic Fatty (ZDF) rats: Correlation with pancreatic betacell function
-
doi:10.1111/j. 1469-7580.2010.01285.x. PubMed: 20807269
-
Paulsen SJ, Vrang N, Larsen LK, Larsen PJ, Jelsing J (2010) Stereological assessment of pancreatic beta-cell mass development in male Zucker Diabetic Fatty (ZDF) rats: correlation with pancreatic betacell function. J Anat 217:624-630. doi:10.1111/j. 1469-7580.2010.01285.x. PubMed: 20807269.
-
(2010)
J Anat
, vol.217
, pp. 624-630
-
-
Paulsen, S.J.1
Vrang, N.2
Larsen, L.K.3
Larsen, P.J.4
Jelsing, J.5
-
28
-
-
0037677695
-
Increased islet volume but unchanged islet number in ob/ob mice
-
Bock T, Pakkenberg B, Buschard K (2003) Increased islet volume but unchanged islet number in ob/ob mice. Diabetes 52:1716-1722. doi: 10.2337/diabetes.52.7.1716. PubMed: 12829638. (Pubitemid 36792462)
-
(2003)
Diabetes
, vol.52
, Issue.7
, pp. 1716-1722
-
-
Bock, T.1
Pakkenberg, B.2
Buschard, K.3
-
29
-
-
79955026350
-
Designbased stereology: Introduction to basic concepts and practical approaches for estimation of cell number
-
doi:10.1177/0192623310385140. PubMed: 21030683
-
Boyce RW, Dorph-Petersen KA, Lyck L, Gundersen HJ (2010) Designbased stereology: introduction to basic concepts and practical approaches for estimation of cell number. Toxicol Pathol 38:1011-1025. doi:10.1177/ 0192623310385140. PubMed: 21030683.
-
(2010)
Toxicol Pathol
, vol.38
, pp. 1011-1025
-
-
Boyce, R.W.1
Dorph-Petersen, K.A.2
Lyck, L.3
Gundersen, H.J.4
-
30
-
-
78650777899
-
Reversibility of hyperglycaemia and islet abnormalities in the high fatfed female ZDF rat model of type 2 diabetes
-
doi:10.1016/j.vascn. 2010.04.001. PubMed: 20398780
-
Teague J, Gyte A, Peel JE, Young KC, Loxham SJ et al. (2011) Reversibility of hyperglycaemia and islet abnormalities in the high fatfed female ZDF rat model of type 2 diabetes. J Pharmacol Toxicol Methods 63:15-23. doi:10.1016/j.vascn. 2010.04.001. PubMed: 20398780.
-
(2011)
J Pharmacol Toxicol Methods
, vol.63
, pp. 15-23
-
-
Teague, J.1
Gyte, A.2
Peel, J.E.3
Young, K.C.4
Loxham, S.J.5
-
31
-
-
0019749949
-
The influence of genetic background on the expression of mutations at the diabetes locus in the mouse. III. Effect of H-2 haplotype and sex
-
doi:10.2337/diab.30.12.1029. PubMed: 7030828
-
Leiter EH, Coleman DL, Hummel KP (1981) The influence of genetic background on the expression of mutations at the diabetes locus in the mouse. III. Effect of H-2 haplotype and sex. Diabetes 30:1029-1034. doi:10.2337/diab.30.12.1029. PubMed: 7030828.
-
(1981)
Diabetes
, vol.30
, pp. 1029-1034
-
-
Leiter, E.H.1
Coleman, D.L.2
Hummel, K.P.3
-
32
-
-
0015381515
-
The influence of genetic background on expression of mutations at the diabetes locus in the mouse. I. C57BL-KsJ and C57BL-6J strains
-
doi:10.1007/BF00487005. PubMed: 4557514
-
Hummel KP, Coleman DL, Lane PW (1972) The influence of genetic background on expression of mutations at the diabetes locus in the mouse. I. C57BL-KsJ and C57BL-6J strains. Biochem Genet 7:1-13. doi:10.1007/BF00487005. PubMed: 4557514.
-
(1972)
Biochem Genet
, vol.7
, pp. 1-13
-
-
Hummel, K.P.1
Coleman, D.L.2
Lane, P.W.3
-
33
-
-
73549105431
-
Molecular analysis of db gene-related pancreatic beta cell dysfunction; evidence for a compensatory mechanism inhibiting development of diabetes in the db gene heterozygote
-
doi:10.1507/endocrj. K09E-028. PubMed: 19706988
-
Kanda Y, Shimoda M, Tawaramoto K, Hamamoto S, Tatsumi F et al. (2009) Molecular analysis of db gene-related pancreatic beta cell dysfunction; evidence for a compensatory mechanism inhibiting development of diabetes in the db gene heterozygote. Endocr J 56:997-1008. doi:10.1507/endocrj. K09E-028. PubMed: 19706988.
-
(2009)
Endocr J
, vol.56
, pp. 997-1008
-
-
Kanda, Y.1
Shimoda, M.2
Tawaramoto, K.3
Hamamoto, S.4
Tatsumi, F.5
-
34
-
-
0032999544
-
Neogenesis vs apoptosis as main components of pancreatic β cell mass changes in glucose-infused normal and mildly diabetic adult rats
-
Bernard C, Berthault MF, Saulnier C, Ktorza A (1999) Neogenesis vs. apoptosis As main components of pancreatic beta cell ass changes in glucose-infused normal and mildly diabetic adult rats. FASEB J 13:1195-1205. PubMed: 10385610. (Pubitemid 29300365)
-
(1999)
FASEB Journal
, vol.13
, Issue.10
, pp. 1195-1205
-
-
Bernard, C.1
Berthault, M.-F.2
Saulnier, C.3
Ktorza, A.4
-
35
-
-
5644251769
-
Metabolic adaptations to chronic glucose infusion in rats
-
DOI 10.1007/s00125-004-1493-5
-
Topp BG, McArthur MD, Finegood DT (2004) Metabolic adaptations to chronic glucose infusion in rats. Diabetologia 47:1602-1610. doi: 10.1007/s00125-004- 1493-5. PubMed: 15349726. (Pubitemid 39371643)
-
(2004)
Diabetologia
, vol.47
, Issue.9
, pp. 1602-1610
-
-
Topp, B.G.1
McArthur, M.D.2
Finegood, D.T.3
-
37
-
-
0014802883
-
Physiological factors associated with alterations in beta cell proliferation
-
doi:10.1007/BF01212233. PubMed: 5432353
-
Physiological factors associated with alterations in beta cell proliferation. Diabetologia 6:243-251. doi:10.1007/BF01212233. PubMed: 5432353.
-
Diabetologia
, vol.6
, pp. 243-251
-
-
-
38
-
-
66649128739
-
Adaptive beta-cell proliferation is severely restricted with advanced age
-
doi: 10.2337/db08-1198. PubMed: 19265026
-
Rankin MM, Kushner JA (2009) Adaptive beta-cell proliferation is severely restricted with advanced age. Diabetes 58:1365-1372. doi: 10.2337/db08-1198. PubMed: 19265026.
-
(2009)
Diabetes
, vol.58
, pp. 1365-1372
-
-
Rankin, M.M.1
Kushner, J.A.2
-
39
-
-
0035008598
-
Adaptation of beta-cell mass to substrate oversupply: Enhanced function with normal gene expression
-
PubMed: 11287362
-
Steil GM, Trivedi N, Jonas JC, Hasenkamp WM, Sharma A et al. (2001) Adaptation of beta-cell mass to substrate oversupply: enhanced function with normal gene expression. Am J Physiol Endocrinol Metab 280:E788-E796. PubMed: 11287362.
-
(2001)
Am J Physiol Endocrinol Metab
, vol.280
-
-
Steil, G.M.1
Trivedi, N.2
Jonas, J.C.3
Hasenkamp, W.M.4
Sharma, A.5
-
40
-
-
0028985060
-
Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids
-
doi:10.1074/jbc.270.3.1295. PubMed: 7836394
-
Milburn JL Jr., Hirose H, Lee YH, Nagasawa Y, Ogawa A et al. (1995) Pancreatic beta-cells in obesity. Evidence for induction of functional, morphologic, and metabolic abnormalities by increased long chain fatty acids. J Biol Chem 270:1295-1299. doi:10.1074/jbc.270.3.1295. PubMed: 7836394.
-
(1995)
J Biol Chem
, vol.270
, pp. 1295-1299
-
-
Milburn Jr., J.L.1
Hirose, H.2
Lee, Y.H.3
Nagasawa, Y.4
Ogawa, A.5
-
41
-
-
0042922453
-
Saturated fatty acids synergize with elevated glucose to cause pancreatic β-cell death
-
DOI 10.1210/en.2003-0410
-
El-Assaad W, Buteau J, Peyot ML, Nolan C, Roduit R et al. (2003) Saturated fatty acids synergize with elevated glucose to cause pancreatic beta-cell death. Endocrinology 144:4154-4163. doi: 10.1210/en. 2003-0410. PubMed: 12933690. (Pubitemid 37088771)
-
(2003)
Endocrinology
, vol.144
, Issue.9
, pp. 4154-4163
-
-
El-Assaad, W.1
Buteau, J.2
Peyot, M.-L.3
Nolan, C.4
Roduit, R.5
Hardy, S.6
Joly, E.7
Dbaibo, G.8
Rosenberg, L.9
Prentki, M.10
-
42
-
-
33745863033
-
Islet β cell failure in type 2 diabetes
-
DOI 10.1172/JCI29103
-
Prentki M, Nolan CJ (2006) Islet beta cell failure in type 2 diabetes. J Clin Invest 116:1802-1812. doi:10.1172/JCI29103. PubMed: 16823478. (Pubitemid 44033300)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.7
, pp. 1802-1812
-
-
Prentki, M.1
Nolan, C.J.2
-
43
-
-
76049113712
-
Glucolipotoxicity of the pancreatic beta cell
-
doi:10.1016/j.bbalip. 2009.08.006. PubMed: 19715772
-
Poitout V, Amyot J, Semache M, Zarrouki B, Hagman D et al. (2010) Glucolipotoxicity of the pancreatic beta cell. Biochim Biophys Acta 1801:289-298. doi:10.1016/j.bbalip. 2009.08.006. PubMed: 19715772.
-
(2010)
Biochim Biophys Acta
, vol.1801
, pp. 289-298
-
-
Poitout, V.1
Amyot, J.2
Semache, M.3
Zarrouki, B.4
Hagman, D.5
-
44
-
-
0035432491
-
Glucose Induces β-Cell Apoptosis Via Upregulation of the Fas Receptor in Human Islets
-
Maedler K, Spinas GA, Lehmann R, Sergeev P, Weber M et al. (2001) Glucose induces beta-cell apoptosis via upregulation of the Fas receptor in human islets. Diabetes 50:1683-1690. doi:10.2337/diabetes.50.8.1683. PubMed: 11473025. (Pubitemid 33641583)
-
(2001)
Diabetes
, vol.50
, Issue.8
, pp. 1683-1690
-
-
Maedler, K.1
Spinas, G.A.2
Lehmann, R.3
Sergeev, P.4
Weber, M.5
Fontana, A.6
Kaiser, N.7
Donath, M.Y.8
-
45
-
-
0036797785
-
Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: Possible role of oxidative stress
-
DOI 10.1053/meta.2002.35200
-
Piro S, Anello M, Di Pietro C, Lizzio MN, Patanè G et al. (2002) Chronic exposure to free fatty acids or high glucose induces apoptosis in rat pancreatic islets: possible role of oxidative stress. Metabolism 51:1340-1347. doi:10.1053/meta.2002.35200. PubMed: 12370856. (Pubitemid 35174157)
-
(2002)
Metabolism: Clinical and Experimental
, vol.51
, Issue.10
, pp. 1340-1347
-
-
Piro, S.1
Anello, M.2
Di Pietro, C.3
Lizzio, M.N.4
Patane, G.5
Rabuazzo, A.M.6
Vigneri, R.7
Purrello, M.8
Purrello, F.9
-
46
-
-
0032478314
-
Fatty acid-induced β cell apoptosis: A link between obesity and diabetes
-
DOI 10.1073/pnas.95.5.2498
-
Shimabukuro M, Zhou YT, Levi M, Unger RH (1998) Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes. Proc Natl Acad Sci U S A 95:2498-2502. doi:10.1073/pnas.95.5.2498. PubMed: 9482914. (Pubitemid 28145970)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.5
, pp. 2498-2502
-
-
Shimabukuro, M.1
Zhou, Y.-T.2
Levi, M.3
Unger, R.H.4
-
47
-
-
20044370468
-
Imaging β-cell death with a near-infrared probe
-
DOI 10.2337/diabetes.54.6.1780
-
Medarova Z, Bonner-Weir S, Lipes M, Moore A (2005) Imaging betacell death with a near-infrared probe. Diabetes 54:1780-1788. doi: 10.2337/diabetes.54.6. 1780. PubMed: 15919800. (Pubitemid 40770768)
-
(2005)
Diabetes
, vol.54
, Issue.6
, pp. 1780-1788
-
-
Medarova, Z.1
Bonner-Weir, S.2
Lipes, M.3
Moore, A.4
-
48
-
-
24144496798
-
Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of β-cell differentiation and secretory function in the db/db mouse model of diabetes
-
DOI 10.2337/diabetes.54.9.2755
-
Kjørholt C, Akerfeldt MC, Biden TJ, Laybutt DR (2005) Chronic hyperglycemia, independent of plasma lipid levels, is sufficient for the loss of beta-cell differentiation and secretory function in the db/db mouse model of diabetes. Diabetes 54:2755-2763. doi:10.2337/diabetes.54.9.2755. PubMed: 16123366. (Pubitemid 41233599)
-
(2005)
Diabetes
, vol.54
, Issue.9
, pp. 2755-2763
-
-
Kjorholt, C.1
Akerfeldt, M.C.2
Biden, T.J.3
Laybutt, D.R.4
-
49
-
-
0036738398
-
Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets
-
doi: 10.1172/JCI15318. PubMed: 12235117
-
Maedler K, Sergeev P, Ris F, Oberholzer J, Joller-Jemelka HI et al. (2002) Glucose-induced beta cell production of IL-1beta contributes to glucotoxicity in human pancreatic islets. J Clin Invest 110:851-860. doi: 10.1172/JCI15318. PubMed: 12235117.
-
(2002)
J Clin Invest
, vol.110
, pp. 851-860
-
-
Maedler, K.1
Sergeev, P.2
Ris, F.3
Oberholzer, J.4
Joller-Jemelka, H.I.5
-
50
-
-
84860872990
-
The role of mammalian target of rapamycin (mTOR) in the regulation of pancreatic beta-cell mass: Implications in the development of type-2 diabetes
-
doi:10.1007/s00018-011-0874-4. PubMed: 22068611
-
Xie J, Herbert TP (2012) The role of mammalian target of rapamycin (mTOR) in the regulation of pancreatic beta-cell mass: implications in the development of type-2 diabetes. Cell Mol Life Sci 69:1289-1304. doi:10.1007/s00018-011- 0874-4. PubMed: 22068611.
-
(2012)
Cell Mol Life Sci
, vol.69
, pp. 1289-1304
-
-
Xie, J.1
Herbert, T.P.2
-
51
-
-
0037230114
-
Mitochondrial dysfunction is involved in apoptosis induced by serum withdrawal and fatty acids in the β-cell line INS-1
-
DOI 10.1210/en.2001-211282
-
Maestre I, Jordán J, Calvo S, Reig JA, Ceña V et al. (2003) Mitochondrial dysfunction is involved in apoptosis induced by serum withdrawal and fatty acids in the beta-cell line INS-1. Endocrinology 144:335-345. doi:10.1210/en. 2001-211282. PubMed: 12488362. (Pubitemid 36076123)
-
(2003)
Endocrinology
, vol.144
, Issue.1
, pp. 335-345
-
-
Maestre, I.1
Jordan, J.2
Calvo, S.3
Reig, J.A.4
Cena, V.5
Soria, B.6
Prentki, M.7
Roche, E.8
-
52
-
-
84855181568
-
Mitochondrial dysfunction and beta-cell failure in type 2 diabetes mellitus
-
2012
-
Ma ZA, Zhao Z, Turk J (2012) Mitochondrial dysfunction and beta-cell failure in type 2 diabetes mellitus. Exp Diabetes Res 2012:703538
-
(2012)
Exp Diabetes Res
, pp. 703538
-
-
Ma, Z.A.1
Zhao, Z.2
Turk, J.3
-
53
-
-
2342510386
-
Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation
-
DOI 10.1038/nature02520
-
Dor Y, Brown J, Martinez OI, Melton DA (2004) Adult pancreatic betacells are formed by self-duplication rather than stem-cell differentiation. Nature 429:41-46. doi:10.1038/nature02520. PubMed: 15129273. (Pubitemid 38620543)
-
(2004)
Nature
, vol.429
, Issue.6987
, pp. 41-46
-
-
Dor, Y.1
Brown, J.2
Martinez, O.I.3
Melton, D.A.4
-
54
-
-
41849097354
-
Beta cell mass in diabetes: A realistic therapeutic target?
-
doi:10.1007/s00125-008-0936-9. PubMed: 18317728
-
Meier JJ (2008) Beta cell mass in diabetes: a realistic therapeutic target? Diabetologia 51:703-713. doi:10.1007/s00125-008-0936-9. PubMed: 18317728.
-
(2008)
Diabetologia
, vol.51
, pp. 703-713
-
-
Meier, J.J.1
-
55
-
-
41349117978
-
Preservation of betacell function by targeting beta-cell mass
-
doi:10.1016/j.tips.2008.02.001. PubMed: 18359095
-
de Koning EJ, Bonner-Weir S, Rabelink TJ (2008) Preservation of betacell function by targeting beta-cell mass. Trends Pharmacol Sci 29:218-227. doi:10.1016/j.tips.2008.02.001. PubMed: 18359095.
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 218-227
-
-
De Koning, E.J.1
Bonner-Weir, S.2
Rabelink, T.J.3
-
56
-
-
0038707331
-
Selective β-cell loss and α-cell expansion in patients with type 2 diabetes mellitus in Korea
-
DOI 10.1210/jc.2002-020735
-
Yoon KH, Ko SH, Cho JH, Lee JM, Ahn YB et al. (2003) Selective betacell loss and alpha-cell expansion in patients with type 2 diabetes mellitus in Korea. J Clin Endocrinol Metab 88:2300-2308. doi: 10.1210/jc.2002-020735. PubMed: 12727989. (Pubitemid 36549911)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.5
, pp. 2300-2308
-
-
Yoon, K.H.1
Ko, S.H.2
Cho, J.H.3
Lee, J.M.4
Ahn, Y.B.5
Song, K.H.6
Yoo, S.J.7
Kang, M.I.8
Cha, B.Y.9
Lee, K.W.10
Son, H.Y.11
Kang, S.K.12
Kim, H.S.13
Lee, I.K.14
Bonner-Weir, S.15
-
57
-
-
84872035827
-
Beta-cell mass and turnover in humans: Effects of obesity and aging
-
doi:10.2337/dcS13-2046. PubMed: 22875233
-
Saisho Y, Butler AE, Manesso E, Elashoff D, Rizza RA et al. (2013) beta-cell mass and turnover in humans: effects of obesity and aging. Diabetes Care 36:111-117. doi:10.2337/dcS13-2046. PubMed: 22875233.
-
(2013)
Diabetes Care
, vol.36
, pp. 111-117
-
-
Saisho, Y.1
Butler, A.E.2
Manesso, E.3
Elashoff, D.4
Rizza, R.A.5
-
58
-
-
84872012224
-
Quantifying beta-cells in health and disease: The past, the present, and the need
-
doi:10.2337/dc12-1251. PubMed: 23264284
-
Kahn SE (2013) Quantifying beta-cells in health and disease: the past, the present, and the need. Diabetes Care 36:4-5. doi:10.2337/dc12-1251. PubMed: 23264284.
-
(2013)
Diabetes Care
, vol.36
, pp. 4-5
-
-
Kahn, S.E.1
-
59
-
-
79954543511
-
Beta-cell loss and beta-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition
-
doi:1 016/j.ajpath.2011.02.036. PubMed: 21641386
-
Jurgens CA, Toukatly MN, Fligner CL, Udayasankar J, Subramanian SL et al. (2011) beta-cell loss and beta-cell apoptosis in human type 2 diabetes are related to islet amyloid deposition. Am J Pathol 178:2632-2640. doi:1 016/j.ajpath.2011.02.036. PubMed: 21641386.
-
(2011)
Am J Pathol
, vol.178
, pp. 2632-2640
-
-
Jurgens, C.A.1
Toukatly, M.N.2
Fligner, C.L.3
Udayasankar, J.4
Subramanian, S.L.5
|