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Volumn 288, Issue 3 51-3, 2005, Pages

Structural and functional analysis of pancreatic islets preserved by pioglitazone in db/db mice

Author keywords

Adiponectin; Pancreatic cells; Type 2 diabetes mellitus

Indexed keywords

ADIPONECTIN; FATTY ACID; GLUCOSE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PIOGLITAZONE; TRIACYLGLYCEROL;

EID: 13844262626     PISSN: 01931849     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpendo.00128.2004     Document Type: Article
Times cited : (92)

References (37)
  • 1
    • 0032053701 scopus 로고    scopus 로고
    • TRIPOD (TRoglitazone in the Prevention of Diabetes): A randomized, placebo-controlled trial of troglitazone in women with prior gestational diabetes mellitus
    • Azen SP, Peters RK, Berkowitz K, Kjos S, Xiang A, and Buchanan TA. TRIPOD (TRoglitazone In the Prevention Of Diabetes): a randomized, placebo-controlled trial of troglitazone in women with prior gestational diabetes mellitus. Control Clin Trials 19: 217-231, 1998.
    • (1998) Control Clin Trials , vol.19 , pp. 217-231
    • Azen, S.P.1    Peters, R.K.2    Berkowitz, K.3    Kjos, S.4    Xiang, A.5    Buchanan, T.A.6
  • 2
    • 0036724346 scopus 로고    scopus 로고
    • Preservation of pancreatic β-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk Hispanic women
    • Buchanan TA, Xiang AH, Peters RK, Kjos SL, Marroquin A, Goico J, Ochoa C, Tan S, Berkowitz K, Hodis HN, and Azen SP. Preservation of pancreatic β-cell function and prevention of type 2 diabetes by pharmacological treatment of insulin resistance in high-risk Hispanic women. Diabetes 51: 2796-2803, 2002.
    • (2002) Diabetes , vol.51 , pp. 2796-2803
    • Buchanan, T.A.1    Xiang, A.H.2    Peters, R.K.3    Kjos, S.L.4    Marroquin, A.5    Goico, J.6    Ochoa, C.7    Tan, S.8    Berkowitz, K.9    Hodis, H.N.10    Azen, S.P.11
  • 3
    • 0033842027 scopus 로고    scopus 로고
    • Interactions between insulin resistance and insulin secretion in the development of glucose intolerance
    • Cavaghan MK, Ehrmann DA, and Polonsky KS. Interactions between insulin resistance and insulin secretion in the development of glucose intolerance. J Clin Invest 106: 329-333, 2000.
    • (2000) J Clin Invest , vol.106 , pp. 329-333
    • Cavaghan, M.K.1    Ehrmann, D.A.2    Polonsky, K.S.3
  • 4
    • 0037097039 scopus 로고    scopus 로고
    • Acarbose for prevention of type 2 diabetes mellitus: The STOP-NIDDM randomised trial
    • Chiasson JL, Josse RG, Gomis R, Hanefeld M, Karasik A, and Laakso M; STOP-NIDDM Trail Research Group. Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial. Lancet 359: 2072-2077; 2002.
    • (2002) Lancet , vol.359 , pp. 2072-2077
    • Chiasson, J.L.1    Josse, R.G.2    Gomis, R.3    Hanefeld, M.4    Karasik, A.5    Laakso, M.6
  • 5
    • 0018139377 scopus 로고
    • Obese and diabetes: Two mutant genes causing diabetes-obesity- Syndromes in mice
    • Coleman DL. Obese and diabetes: two mutant genes causing diabetes-obesity- syndromes in mice. Diabetologia 14: 141-148, 1978.
    • (1978) Diabetologia , vol.14 , pp. 141-148
    • Coleman, D.L.1
  • 8
    • 0346157020 scopus 로고    scopus 로고
    • Pioglitazone preserves pancreatic islet structure and insulin secretory function in three murine models of type 2 diabetes
    • Diani AR, Sawada G, Wyse B, Murray FT, and Khan M. Pioglitazone preserves pancreatic islet structure and insulin secretory function in three murine models of type 2 diabetes. Am J Physiol Endocrinol Metab 286: E116-E122, 2004.
    • (2004) Am J Physiol Endocrinol Metab , vol.286
    • Diani, A.R.1    Sawada, G.2    Wyse, B.3    Murray, F.T.4    Khan, M.5
  • 9
    • 0035960122 scopus 로고    scopus 로고
    • Mechanisms of disease: Molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young
    • Fajans SS, Bell GI, and Polonsky KS. Mechanisms of disease: molecular mechanisms and clinical pathophysiology of maturity-onset diabetes of the young. N Engl J Med 345: 971-980, 2001.
    • (2001) N Engl J Med , vol.345 , pp. 971-980
    • Fajans, S.S.1    Bell, G.I.2    Polonsky, K.S.3
  • 11
    • 0035852760 scopus 로고    scopus 로고
    • Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice
    • Fruebis O, Tsao T, Javorschi S, Ebbets-Reed D, Erickson MRS, Yen FT, Bihain BE, and Lodish HF. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. Proc Nad Acad Sci USA 98: 2005-2010, 2001.
    • (2001) Proc Nad Acad Sci USA , vol.98 , pp. 2005-2010
    • Fruebis, O.1    Tsao, T.2    Javorschi, S.3    Ebbets-Reed, D.4    Erickson, M.R.S.5    Yen, F.T.6    Bihain, B.E.7    Lodish, H.F.8
  • 12
    • 0032520921 scopus 로고    scopus 로고
    • Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats
    • Fujiwara T, Horikoshi H, Yazaki Y, and Kadowaki T. Troglitazone increases the number of small adipocytes without the change of white adipose tissue mass in obese Zucker rats. J Clin Invest 101: 1354-1361, 1998.
    • (1998) J Clin Invest , vol.101 , pp. 1354-1361
    • Fujiwara, T.1    Horikoshi, H.2    Yazaki, Y.3    Kadowaki, T.4
  • 13
    • 0033613181 scopus 로고    scopus 로고
    • Troglitazone prevents mitchondrial alterations, β-cell destruction, and diabetes in obese prediabetic rats
    • Higa M, Zhou YT, Ravazzola M, Baetens D, Orci L, and Unger RH. Troglitazone prevents mitchondrial alterations, β-cell destruction, and diabetes in obese prediabetic rats. Proc Natl Acad Sci USA 96: 11513-11518, 1999.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 11513-11518
    • Higa, M.1    Zhou, Y.T.2    Ravazzola, M.3    Baetens, D.4    Orci, L.5    Unger, R.H.6
  • 15
    • 0035039227 scopus 로고    scopus 로고
    • Circulating concentrarions of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in Rhesus monkeys
    • Hotta K, Funahashi T, Bodkin NB, Ortmeyer HK, Arita Y, Hansen BC, and Matsuzawa Y. Circulating concentrarions of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in Rhesus monkeys. Diabetes 50: 1126-1133, 2001.
    • (2001) Diabetes , vol.50 , pp. 1126-1133
    • Hotta, K.1    Funahashi, T.2    Bodkin, N.B.3    Ortmeyer, H.K.4    Arita, Y.5    Hansen, B.C.6    Matsuzawa, Y.7
  • 16
    • 0014004384 scopus 로고
    • Diabetes, a new mutation in the mouse
    • Hummel KP, Dickie MM, and Coleman DL. Diabetes, a new mutation in the mouse. Science 153: 1127-1128, 1966.
    • (1966) Science , vol.153 , pp. 1127-1128
    • Hummel, K.P.1    Dickie, M.M.2    Coleman, D.L.3
  • 17
    • 0024343196 scopus 로고
    • Genetic analysis of obesity-induced diabetes associated with limited capacity to synthesize insulin in C57BL/KS mice: Evidence for polygenic control
    • Kaku K, Province M, and Permutt MA. Genetic analysis of obesity-induced diabetes associated with limited capacity to synthesize insulin in C57BL/KS mice: evidence for polygenic control. Diabetologia 32: 636-643, 1989.
    • (1989) Diabetologia , vol.32 , pp. 636-643
    • Kaku, K.1    Province, M.2    Permutt, M.A.3
  • 20
    • 0018899699 scopus 로고
    • Increase in insulin response after treatment of overt maturity-onset diabetes is independent of the mode of treatment
    • Kosaka K, Kuzuya T, Akanuma Y, and Hagura R. Increase in insulin response after treatment of overt maturity-onset diabetes is independent of the mode of treatment. Diabetologia 18: 23-28, 1980.
    • (1980) Diabetologia , vol.18 , pp. 23-28
    • Kosaka, K.1    Kuzuya, T.2    Akanuma, Y.3    Hagura, R.4
  • 21
    • 0029783411 scopus 로고    scopus 로고
    • Impaired β-cell fonction with chronic hyperglycemia: "over-worked β-cell" hypothesis
    • Leahy JL. Impaired β-cell fonction with chronic hyperglycemia: "over-worked β-cell" hypothesis. Diabetes Rev 4: 298-319, 1996.
    • (1996) Diabetes Rev , vol.4 , pp. 298-319
    • Leahy, J.L.1
  • 23
    • 0027947379 scopus 로고
    • β-Cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: Impairment in adipocyte-β-cell relationships
    • Lee Y, Hirose H, Ohneda M, Johnson JH, McGarry JD, and Unger RH. β-Cell lipotoxicity in the pathogenesis of non-insulin-dependent diabetes mellitus of obese rats: impairment in adipocyte-β-cell relationships. Proc Natl Acad Sci USA 91: 10878-10882, 1994.
    • (1994) Proc Natl Acad Sci USA , vol.91 , pp. 10878-10882
    • Lee, Y.1    Hirose, H.2    Ohneda, M.3    Johnson, J.H.4    McGarry, J.D.5    Unger, R.H.6
  • 24
    • 0029978571 scopus 로고    scopus 로고
    • Normalization by insulin treatment of low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of the GK rats
    • MacDonald MJ, Efendic S, and Ostenson CG. Normalization by insulin treatment of low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of the GK rats. Diabetes 45: 886-890, 1996.
    • (1996) Diabetes , vol.45 , pp. 886-890
    • MacDonald, M.J.1    Efendic, S.2    Ostenson, C.G.3
  • 26
    • 0030055324 scopus 로고    scopus 로고
    • Metabolic signaling of insulin secretion
    • Malaisse WJ. Metabolic signaling of insulin secretion. Diabetes Rev 4: 145-149, 1996.
    • (1996) Diabetes Rev , vol.4 , pp. 145-149
    • Malaisse, W.J.1
  • 27
    • 0036517099 scopus 로고    scopus 로고
    • Dose-response effect of pioglitazone on insulin sensitivity and insulin secretion in type 2 diabetes
    • Miyazaki Y, Matsuda M, and DeFronzo RA. Dose-response effect of pioglitazone on insulin sensitivity and insulin secretion in type 2 diabetes. Diabetes Care 25: 517-523, 2002.
    • (2002) Diabetes Care , vol.25 , pp. 517-523
    • Miyazaki, Y.1    Matsuda, M.2    DeFronzo, R.A.3
  • 28
    • 0023597445 scopus 로고
    • Quantitative analysis of pancreatic proinsulin mRNA in genetically diabetic (db/db) mice
    • Orland MJ and Permutt MA. Quantitative analysis of pancreatic proinsulin mRNA in genetically diabetic (db/db) mice. Diabetes 37: 341-347, 1987.
    • (1987) Diabetes , vol.37 , pp. 341-347
    • Orland, M.J.1    Permutt, M.A.2
  • 29
    • 0036153256 scopus 로고    scopus 로고
    • Mini review: Secondary β-cell failure in type 2 diabetes - A convergence of glucotoxicity and lipotoxicity
    • Poitout V and Robertson RP. Mini review: secondary β-cell failure in type 2 diabetes - a convergence of glucotoxicity and lipotoxicity. Endocrinology 143: 339-342, 2002.
    • (2002) Endocrinology , vol.143 , pp. 339-342
    • Poitout, V.1    Robertson, R.P.2
  • 30
    • 0032488968 scopus 로고    scopus 로고
    • Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats
    • Shimabukuro M, Zhou YT, Lee Y, and Unger RH. Troglitazone lowers islet fat and restores beta cell function of Zucker diabetic fatty rats. J Biol Chem 273: 3547-3550, 1998.
    • (1998) J Biol Chem , vol.273 , pp. 3547-3550
    • Shimabukuro, M.1    Zhou, Y.T.2    Lee, Y.3    Unger, R.H.4
  • 31
    • 0032478314 scopus 로고    scopus 로고
    • Fatty acid-induced β-cell apoptosis: A link between obesity and diabetes
    • Shimabukuro M, Zhou YT, Levi M, and Unger KH. Fatty acid-induced β-cell apoptosis: a link between obesity and diabetes. Proc Natl Acad Sci USA 95: 2498-2502, 1998.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2498-2502
    • Shimabukuro, M.1    Zhou, Y.T.2    Levi, M.3    Unger, K.H.4
  • 32
    • 0034021443 scopus 로고    scopus 로고
    • The novel hypoglycemic agent YM440 normalizes hyperglycemia without changing body fat weight in diabetic db/db mice
    • Shimaya A, Kurosaki E, Nakano R, Hirayama R, Shibasaki M, and Shikama H. The novel hypoglycemic agent YM440 normalizes hyperglycemia without changing body fat weight in diabetic db/db mice. Metabolism 49: 411-417, 2000.
    • (2000) Metabolism , vol.49 , pp. 411-417
    • Shimaya, A.1    Kurosaki, E.2    Nakano, R.3    Hirayama, R.4    Shibasaki, M.5    Shikama, H.6
  • 33
    • 0028229508 scopus 로고
    • Insulin resistance or insulin deficiency: Which is the primary cause of NIDDM?
    • Taylor SI, Accili D, and Imai Y. Insulin resistance or insulin deficiency: which is the primary cause of NIDDM? Diabetes Care 43: 735-740, 1994.
    • (1994) Diabetes Care , vol.43 , pp. 735-740
    • Taylor, S.I.1    Accili, D.2    Imai, Y.3
  • 34
    • 0029151863 scopus 로고
    • Lipotoxicity in the pathogenesis of obesity-dependent NIDDM: Genetic and clinical implications
    • Unger RH. Lipotoxicity in the pathogenesis of obesity-dependent NIDDM: genetic and clinical implications. Diabetes 44: 863-870, 1995.
    • (1995) Diabetes , vol.44 , pp. 863-870
    • Unger, R.H.1
  • 37
    • 0026731869 scopus 로고
    • Glucose toxicity
    • Yki-Jarvinen H. Glucose toxicity. Endocr Rev 12: 415-431, 1992.
    • (1992) Endocr Rev , vol.12 , pp. 415-431
    • Yki-Jarvinen, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.