-
1
-
-
0021194420
-
Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure
-
Cohn JN, Levine TB, Olivari MT, et al. Plasma norepinephrine as a guide to prognosis in patients with chronic congestive heart failure. N Engl J Med 1984;311(13):819-23
-
(1984)
N Engl J Med
, vol.311
, Issue.13
, pp. 819-823
-
-
Cohn, J.N.1
Levine, T.B.2
Olivari, M.T.3
-
2
-
-
0027819354
-
Beta-adrenoceptors in cardiac disease
-
Brodde OE. Beta-adrenoceptors in cardiac disease. Pharmacol Ther 1993;60(3):405-30
-
(1993)
Pharmacol Ther
, vol.60
, Issue.3
, pp. 405-430
-
-
Brodde, O.E.1
-
3
-
-
0029061324
-
Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor
-
Koch WJ, Rockman HA, Samama P, et al. Cardiac function in mice overexpressing the beta-adrenergic receptor kinase or a beta ARK inhibitor. Science 1995;268(5215):1350-3
-
(1995)
Science
, vol.268
, Issue.5215
, pp. 1350-1353
-
-
Koch, W.J.1
Rockman, H.A.2
Samama, P.3
-
4
-
-
50949099098
-
G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure
-
Raake PW, Vinge LE, Gao E, et al. G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure. Circ Res 2008;103(4):413-22
-
(2008)
Circ Res
, vol.103
, Issue.4
, pp. 413-422
-
-
Raake, P.W.1
Vinge, L.E.2
Gao, E.3
-
5
-
-
0027481032
-
The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase
-
Koch WJ, Inglese J, Stone WC, Lefkowitz RJ. The binding site for the beta gamma subunits of heterotrimeric G proteins on the beta-adrenergic receptor kinase. J Biol Chem 1993;268(11):8256-60
-
(1993)
J Biol Chem
, vol.268
, Issue.11
, pp. 8256-8260
-
-
Koch, W.J.1
Inglese, J.2
Stone, W.C.3
Lefkowitz, R.J.4
-
6
-
-
0030726783
-
Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer
-
Akhter SA, Skaer CA, Kypson AP, et al. Restoration of beta-adrenergic signaling in failing cardiac ventricular myocytes via adenoviral-mediated gene transfer. Proc Natl Acad Sci USA 1997;94(22):12100-5
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, Issue.22
, pp. 12100-12105
-
-
Akhter, S.A.1
Skaer, C.A.2
Kypson, A.P.3
-
7
-
-
1842526833
-
Targeted beta-adrenergic receptor kinase (betaARK1) inhibition by gene transfer in failing human hearts
-
Williams ML, Hata JA, Schroder J, et al. Targeted beta-adrenergic receptor kinase (betaARK1) inhibition by gene transfer in failing human hearts. Circulation 2004;109(13):1590-3
-
(2004)
Circulation
, vol.109
, Issue.13
, pp. 1590-1593
-
-
Williams, M.L.1
Hata, J.A.2
Schroder, J.3
-
8
-
-
0034625008
-
Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction
-
White DC, Hata JA, Shah AS, et al. Preservation of myocardial beta-adrenergic receptor signaling delays the development of heart failure after myocardial infarction. Proc Natl Acad Sci USA 2000;97(10):5428-33
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.10
, pp. 5428-5433
-
-
White, D.C.1
Hata, J.A.2
Shah, A.S.3
-
9
-
-
0035814968
-
In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction
-
Shah AS, White DC, Emani S, et al. In vivo ventricular gene delivery of a beta-adrenergic receptor kinase inhibitor to the failing heart reverses cardiac dysfunction. Circulation 2001;103(9):1311-16
-
(2001)
Circulation
, vol.103
, Issue.9
, pp. 1311-1316
-
-
Shah, A.S.1
White, D.C.2
Emani, S.3
-
10
-
-
84860350915
-
AAV6.betaARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model
-
Raake PW, Schlegel P, Ksienzyk J, et al. AAV6.betaARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model. Eur Heart J 2013;34(19):1437-47
-
(2013)
Eur Heart J
, vol.34
, Issue.19
, pp. 1437-1447
-
-
Raake, P.W.1
Schlegel, P.2
Ksienzyk, J.3
-
11
-
-
78349313123
-
Level of G protein-coupled receptor kinase-2 determines myocardial ischemia/reperfusion injury via pro-and anti-apoptotic mechanisms
-
Brinks H, Boucher M, Gao E, et al. Level of G protein-coupled receptor kinase-2 determines myocardial ischemia/reperfusion injury via pro-and anti-apoptotic mechanisms. Circ Res 2010;107(9):1140-9
-
(2010)
Circ Res
, vol.107
, Issue.9
, pp. 1140-1149
-
-
Brinks, H.1
Boucher, M.2
Gao, E.3
-
12
-
-
84876413668
-
Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting
-
Chen M, Sato PY, Chuprun JK, et al. Prodeath signaling of G protein-coupled receptor kinase 2 in cardiac myocytes after ischemic stress occurs via extracellular signal-regulated kinase-dependent heat shock protein 90-mediated mitochondrial targeting. Circ Res 2013;112(8):1121-34
-
(2013)
Circ Res
, vol.112
, Issue.8
, pp. 1121-1134
-
-
Chen, M.1
Sato, P.Y.2
Chuprun, J.K.3
-
13
-
-
79953674475
-
Unanticipated signaling events associated with cardiac adenylyl cyclase gene transfer
-
Gao MH, Hammond HK. Unanticipated signaling events associated with cardiac adenylyl cyclase gene transfer. J Mol Cell Cardiol 2011;50(5):751-8
-
(2011)
J Mol Cell Cardiol
, vol.50
, Issue.5
, pp. 751-758
-
-
Gao, M.H.1
Hammond, H.K.2
-
14
-
-
84862019383
-
Prospects for gene transfer for clinical heart failure
-
Tang T, Gao MH, Hammond HK. Prospects for gene transfer for clinical heart failure. Gene Ther 2012;19(6):606-12
-
(2012)
Gene Ther
, vol.19
, Issue.6
, pp. 606-612
-
-
Tang, T.1
Gao, M.H.2
Hammond, H.K.3
-
15
-
-
0033607665
-
The molecular basis for distinct beta-adrenergic receptor subtype actions in cardiomyocytes
-
Steinberg SF. The molecular basis for distinct beta-adrenergic receptor subtype actions in cardiomyocytes. Circ Res 1999;85(11):1101-11
-
(1999)
Circ Res
, vol.85
, Issue.11
, pp. 1101-1111
-
-
Steinberg, S.F.1
-
16
-
-
3242660757
-
Intracoronary adenovirus encoding adenylyl cyclase VI increases left ventricular function in heart failure
-
Lai NC, Roth DM, Gao MH, et al. Intracoronary adenovirus encoding adenylyl cyclase VI increases left ventricular function in heart failure. Circulation 2004;110(3):330-6
-
(2004)
Circulation
, vol.110
, Issue.3
, pp. 330-336
-
-
Lai, N.C.1
Roth, D.M.2
Gao, M.H.3
-
17
-
-
0034619585
-
Intracoronary delivery of adenovirus encoding adenylyl cyclase VI increases left ventricular function and cAMP-generating capacity
-
Lai NC, Roth DM, Gao MH, et al. Intracoronary delivery of adenovirus encoding adenylyl cyclase VI increases left ventricular function and cAMP-generating capacity. Circulation 2000;102(19):2396-401
-
(2000)
Circulation
, vol.102
, Issue.19
, pp. 2396-2401
-
-
Lai, N.C.1
Roth, D.M.2
Gao, M.H.3
-
18
-
-
84862010808
-
Sarcoplasmic reticulum and calcium cycling targeting by gene therapy
-
Hulot JS, Senyei G, Hajjar RJ. Sarcoplasmic reticulum and calcium cycling targeting by gene therapy. Gene Ther 2012;19(6):596-9
-
(2012)
Gene Ther
, vol.19
, Issue.6
, pp. 596-599
-
-
Hulot, J.S.1
Senyei, G.2
Hajjar, R.J.3
-
19
-
-
80052963462
-
Calcium cycling proteins and their association with heart failure
-
Hadri L, Hajjar RJ. Calcium cycling proteins and their association with heart failure. Clin Pharmacol Ther 2011;90(4):620-4
-
(2011)
Clin Pharmacol Ther
, vol.90
, Issue.4
, pp. 620-624
-
-
Hadri, L.1
Hajjar, R.J.2
-
20
-
-
72449171512
-
Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure
-
Lipskaia L, Chemaly ER, Hadri L, et al. Sarcoplasmic reticulum Ca(2+) ATPase as a therapeutic target for heart failure. Expert Opin Biol Ther 2010;10(1):29-41
-
(2010)
Expert Opin Biol Ther
, vol.10
, Issue.1
, pp. 29-41
-
-
Lipskaia, L.1
Chemaly, E.R.2
Hadri, L.3
-
21
-
-
50649097202
-
The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: A potent target for cardiovascular diseases
-
Kawase Y, Hajjar RJ. The cardiac sarcoplasmic/endoplasmic reticulum calcium ATPase: a potent target for cardiovascular diseases. Nat Clin Pract Cardiovasc Med 2008;5(9):554-65
-
(2008)
Nat Clin Pract Cardiovasc Med
, vol.5
, Issue.9
, pp. 554-565
-
-
Kawase, Y.1
Hajjar, R.J.2
-
22
-
-
56349118816
-
Recirculating cardiac delivery of AAV2/1SERCA2a improves myocardial function in an experimental model of heart failure in large animals
-
Byrne MJ, Power JM, Preovolos A, et al. Recirculating cardiac delivery of AAV2/1SERCA2a improves myocardial function in an experimental model of heart failure in large animals. Gene Ther 2008;15(23):1550-7
-
(2008)
Gene Ther
, vol.15
, Issue.23
, pp. 1550-1557
-
-
Byrne, M.J.1
Power, J.M.2
Preovolos, A.3
-
23
-
-
79951824228
-
Augmentation of left ventricular mechanics by recirculation-mediated AAV2/1-SERCA2a gene delivery in experimental heart failure
-
Mariani JA, Smolic A, Preovolos A, et al. Augmentation of left ventricular mechanics by recirculation-mediated AAV2/1-SERCA2a gene delivery in experimental heart failure. Eur J Heart Fail 2011;13(3):247-53
-
(2011)
Eur J Heart Fail
, vol.13
, Issue.3
, pp. 247-253
-
-
Mariani, J.A.1
Smolic, A.2
Preovolos, A.3
-
24
-
-
68249145908
-
Improvement in cardiac function after sarcoplasmic reticulum Ca2+-ATPase gene transfer in a beagle heart failure model
-
Mi YF, Li XY, Tang LJ, et al. Improvement in cardiac function after sarcoplasmic reticulum Ca2+-ATPase gene transfer in a beagle heart failure model. Chin Med J (Engl) 2009;122(12):1423-8
-
(2009)
Chin Med J (Engl)
, vol.122
, Issue.12
, pp. 1423-1428
-
-
Mi, Y.F.1
Li, X.Y.2
Tang, L.J.3
-
25
-
-
77957914859
-
Gene delivery of sarcoplasmic reticulum calcium ATPase inhibits ventricular remodeling in ischemic mitral regurgitation
-
Beeri R, Chaput M, Guerrero JL, et al. Gene delivery of sarcoplasmic reticulum calcium ATPase inhibits ventricular remodeling in ischemic mitral regurgitation. Circ Heart Fail 2010;3(5):627-34
-
(2010)
Circ Heart Fail
, vol.3
, Issue.5
, pp. 627-634
-
-
Beeri, R.1
Chaput, M.2
Guerrero, J.L.3
-
26
-
-
79961032369
-
Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): A phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure
-
Jessup M, Greenberg B, Mancini D, et al. Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID): a phase 2 trial of intracoronary gene therapy of sarcoplasmic reticulum Ca2+-ATPase in patients with advanced heart failure. Circulation 2011;124(3):304-13
-
(2011)
Circulation
, vol.124
, Issue.3
, pp. 304-313
-
-
Jessup, M.1
Greenberg, B.2
Mancini, D.3
-
27
-
-
62649133817
-
Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial
-
Jaski BE, Jessup ML, Mancini DM, et al. Calcium upregulation by percutaneous administration of gene therapy in cardiac disease (CUPID Trial), a first-in-human phase 1/2 clinical trial. J Card Fail 2009;15(3):171-81
-
(2009)
J Card Fail
, vol.15
, Issue.3
, pp. 171-181
-
-
Jaski, B.E.1
Jessup, M.L.2
Mancini, D.M.3
-
28
-
-
61949300248
-
Rescue of Ca2+ overload-induced left ventricular dysfunction by targeted ablation of phospholamban
-
Tsuji T, Del Monte F, Yoshikawa Y, et al. Rescue of Ca2+ overload-induced left ventricular dysfunction by targeted ablation of phospholamban. Am J Physiol Heart Circ Physiol 2009;296(2):H310-17
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.296
, Issue.2
-
-
Tsuji, T.1
Del Monte, F.2
Yoshikawa, Y.3
-
29
-
-
0036278933
-
Targeting Ca2+ cycling proteins and the action potential in heart failure by gene transfer
-
Kaprielian R, del Monte F, Hajjar RJ. Targeting Ca2+ cycling proteins and the action potential in heart failure by gene transfer. Basic Res Cardiol 2002;97(Suppl 1):I136-45
-
(2002)
Basic Res Cardiol
, vol.97
, Issue.SUPPL. 1
-
-
Kaprielian, R.1
Del Monte, F.2
Hajjar, R.J.3
-
30
-
-
0033615645
-
Chronic phospholamban-sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy
-
Minamisawa S, Hoshijima M, Chu G, et al. Chronic phospholamban- sarcoplasmic reticulum calcium ATPase interaction is the critical calcium cycling defect in dilated cardiomyopathy. Cell 1999;99(3):313-22
-
(1999)
Cell
, vol.99
, Issue.3
, pp. 313-322
-
-
Minamisawa, S.1
Hoshijima, M.2
Chu, G.3
-
31
-
-
0038464639
-
Phospholamban: A crucial regulator of cardiac contractility
-
MacLennan DH, Kranias EG. Phospholamban: a crucial regulator of cardiac contractility. Nat Rev Mol Cell Biol 2003;4(7):566-77
-
(2003)
Nat Rev Mol Cell Biol
, vol.4
, Issue.7
, pp. 566-577
-
-
Maclennan, D.H.1
Kranias, E.G.2
-
32
-
-
41049089262
-
Phospholamban overexpression in transgenic rabbits
-
Pattison JS, Waggoner JR, James J, et al. Phospholamban overexpression in transgenic rabbits. Transgenic Res 2008;17(2):157-70
-
(2008)
Transgenic Res
, vol.17
, Issue.2
, pp. 157-170
-
-
Pattison, J.S.1
Waggoner, J.R.2
James, J.3
-
33
-
-
0036341380
-
Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery
-
Hoshijima M, Ikeda Y, Iwanaga Y, et al. Chronic suppression of heart-failure progression by a pseudophosphorylated mutant of phospholamban via in vivo cardiac rAAV gene delivery. Nat Med 2002;8(8):864-71
-
(2002)
Nat Med
, vol.8
, Issue.8
, pp. 864-871
-
-
Hoshijima, M.1
Ikeda, Y.2
Iwanaga, Y.3
-
34
-
-
85047689989
-
Chronic phospholamban inhibition prevents progressive cardiac dysfunction and pathological remodeling after infarction in rats
-
Iwanaga Y, Hoshijima M, Gu Y, et al. Chronic phospholamban inhibition prevents progressive cardiac dysfunction and pathological remodeling after infarction in rats. J Clin Invest 2004;113(5):727-36
-
(2004)
J Clin Invest
, vol.113
, Issue.5
, pp. 727-736
-
-
Iwanaga, Y.1
Hoshijima, M.2
Gu, Y.3
-
35
-
-
0034624993
-
Adenovirus-based phospholamban antisense expression as a novel approach to improve cardiac contractile dysfunction: Comparison of a constitutive viral versus an endothelin-1-responsive cardiac promoter
-
Eizema K, Fechner H, Bezstarosti K, et al. Adenovirus-based phospholamban antisense expression as a novel approach to improve cardiac contractile dysfunction: comparison of a constitutive viral versus an endothelin-1- responsive cardiac promoter. Circulation 2000;101(18):2193-9
-
(2000)
Circulation
, vol.101
, Issue.18
, pp. 2193-2199
-
-
Eizema, K.1
Fechner, H.2
Bezstarosti, K.3
-
36
-
-
34447096547
-
Percutaneous cardiac recirculation-mediated gene transfer of an inhibitory phospholamban peptide reverses advanced heart failure in large animals
-
Kaye DM, Preovolos A, Marshall T, et al. Percutaneous cardiac recirculation-mediated gene transfer of an inhibitory phospholamban peptide reverses advanced heart failure in large animals. J Am Coll Cardiol 2007;50(3):253-60
-
(2007)
J Am Coll Cardiol
, vol.50
, Issue.3
, pp. 253-260
-
-
Kaye, D.M.1
Preovolos, A.2
Marshall, T.3
-
37
-
-
63649117394
-
Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy
-
Suckau L, Fechner H, Chemaly E, et al. Long-term cardiac-targeted RNA interference for the treatment of heart failure restores cardiac function and reduces pathological hypertrophy. Circulation 2009;119(9):1241-52
-
(2009)
Circulation
, vol.119
, Issue.9
, pp. 1241-1252
-
-
Suckau, L.1
Fechner, H.2
Chemaly, E.3
-
38
-
-
0037470512
-
Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban
-
Schmitt JP, Kamisago M, Asahi M, et al. Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban. Science 2003;299(5611):1410-13
-
(2003)
Science
, vol.299
, Issue.5611
, pp. 1410-1413
-
-
Schmitt, J.P.1
Kamisago, M.2
Asahi, M.3
-
39
-
-
34249882040
-
S100A1: A novel inotropic regulator of cardiac performance. Transition from molecular physiology to pathophysiological relevance
-
Most P, Remppis A, Pleger ST, et al. S100A1: a novel inotropic regulator of cardiac performance. Transition from molecular physiology to pathophysiological relevance. Am J Physiol Regul Integr Comp Physiol 2007;293(2):R568-77
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.293
, Issue.2
-
-
Most, P.1
Remppis, A.2
Pleger, S.T.3
-
40
-
-
85047694125
-
Cardiac adenoviral S100A1 gene delivery rescues failing myocardium
-
Most P, Pleger ST, Volkers M, et al. Cardiac adenoviral S100A1 gene delivery rescues failing myocardium. J Clin Invest 2004;114(11):1550-63
-
(2004)
J Clin Invest
, vol.114
, Issue.11
, pp. 1550-1563
-
-
Most, P.1
Pleger, S.T.2
Volkers, M.3
-
41
-
-
34248570118
-
Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue
-
Pleger ST, Most P, Boucher M, et al. Stable myocardial-specific AAV6-S100A1 gene therapy results in chronic functional heart failure rescue. Circulation 2007;115(19):2506-15
-
(2007)
Circulation
, vol.115
, Issue.19
, pp. 2506-2515
-
-
Pleger, S.T.1
Most, P.2
Boucher, M.3
-
42
-
-
79960696509
-
Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model
-
Pleger ST, Shan C, Ksienzyk J, et al. Cardiac AAV9-S100A1 gene therapy rescues post-ischemic heart failure in a preclinical large animal model. Sci Transl Med 2011;3(92):92ra64
-
(2011)
Sci Transl Med
, vol.3
, Issue.92
-
-
Pleger, S.T.1
Shan, C.2
Ksienzyk, J.3
-
43
-
-
0025266820
-
Ventricular remodeling after myocardial infarction, Experimental observations and clinical implications
-
Pfeffer MA, Braunwald E. Ventricular remodeling after myocardial infarction. Experimental observations and clinical implications. Circulation 1990;81(4):1161-72
-
(1990)
Circulation
, vol.81
, Issue.4
, pp. 1161-1172
-
-
Pfeffer, M.A.1
Braunwald, E.2
-
44
-
-
0032718483
-
Parvalbumin gene transfer corrects diastolic dysfunction in diseased cardiac myocytes
-
Wahr PA, Michele DE, Metzger JM. Parvalbumin gene transfer corrects diastolic dysfunction in diseased cardiac myocytes. Proc Natl Acad Sci USA 1999;96(21):11982-5
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.21
, pp. 11982-11985
-
-
Wahr, P.A.1
Michele, D.E.2
Metzger, J.M.3
-
45
-
-
2442710177
-
Parvalbumin corrects slowed relaxation in adult cardiac myocytes expressing hypertrophic cardiomyopathy-linked alpha-tropomyosin mutations
-
Coutu P, Bennett CN, Favre EG, et al. Parvalbumin corrects slowed relaxation in adult cardiac myocytes expressing hypertrophic cardiomyopathy-linked alpha-tropomyosin mutations. Circ Res 2004;94(9):1235-41
-
(2004)
Circ Res
, vol.94
, Issue.9
, pp. 1235-1241
-
-
Coutu, P.1
Bennett, C.N.2
Favre, E.G.3
-
46
-
-
84875225507
-
Noncanonical EF-hand motif strategically delays Ca2+ buffering to enhance cardiac performance
-
Wang W, Barnabei MS, Asp ML, et al. Noncanonical EF-hand motif strategically delays Ca2+ buffering to enhance cardiac performance. Nat Med 2013;19(3):305-12
-
(2013)
Nat Med
, vol.19
, Issue.3
, pp. 305-312
-
-
Wang, W.1
Barnabei, M.S.2
Asp, M.L.3
-
47
-
-
78651234740
-
Therapeutic angiogenesis for cardiovascular disease: Biological context challenges prospects
-
Zachary I, Morgan RD. Therapeutic angiogenesis for cardiovascular disease: biological context, challenges, prospects. Heart 2011;97(3):181-9
-
(2011)
Heart
, vol.97
, Issue.3
, pp. 181-189
-
-
Zachary, I.1
Morgan, R.D.2
-
48
-
-
84859870640
-
Effect of vascular endothelial growth factor gene transfer on infarct size, left ventricular function and myocardial perfusion in sheep after 2 months of coronary artery occlusion
-
Vera Janavel GL, De Lorenzi A, Cortes C, et al. Effect of vascular endothelial growth factor gene transfer on infarct size, left ventricular function and myocardial perfusion in sheep after 2 months of coronary artery occlusion. J Gene Med 2012;14(4):279-87
-
(2012)
J Gene Med
, vol.14
, Issue.4
, pp. 279-287
-
-
Vera Janavel, G.L.1
De Lorenzi, A.2
Cortes, C.3
-
49
-
-
0033231797
-
Adenoviral-mediated gene transfer induces sustained pericardial VEGF expression in dogs: Effect on myocardial angiogenesis
-
Lazarous DF, Shou M, Stiber JA, et al. Adenoviral-mediated gene transfer induces sustained pericardial VEGF expression in dogs: effect on myocardial angiogenesis. Cardiovasc Res 1999;44(2):294-302
-
(1999)
Cardiovasc Res
, vol.44
, Issue.2
, pp. 294-302
-
-
Lazarous, D.F.1
Shou, M.2
Stiber, J.A.3
-
50
-
-
70350651483
-
Effects of therapeutic angiogenesis with plasmid VEGF165 on ventricular function in a canine model of chronic myocardial infarction
-
Furlani AP, Kalil RA, Castro I, et al. Effects of therapeutic angiogenesis with plasmid VEGF165 on ventricular function in a canine model of chronic myocardial infarction. Rev Bras Cir Cardiovasc 2009;24(2):143-9
-
(2009)
Rev Bras Cir Cardiovasc
, vol.24
, Issue.2
, pp. 143-149
-
-
Furlani, A.P.1
Kalil, R.A.2
Castro, I.3
-
51
-
-
0033544842
-
Intramyocardial gene therapy with naked DNA encoding vascular endothelial growth factor improves collateral flow to ischemic myocardium
-
Tio RA, Tkebuchava T, Scheuermann TH, et al. Intramyocardial gene therapy with naked DNA encoding vascular endothelial growth factor improves collateral flow to ischemic myocardium. Hum Gene Ther 1999;10(18):2953-60
-
(1999)
Hum Gene Ther
, vol.10
, Issue.18
, pp. 2953-2960
-
-
Tio, R.A.1
Tkebuchava, T.2
Scheuermann, T.H.3
-
52
-
-
0036948568
-
Entrance in mitosis of adult cardiomyocytes in ischemic pig hearts after plasmid-mediated rhVEGF165 gene transfer
-
Laguens R, Cabeza Meckert P, Vera Janavel G, et al. Entrance in mitosis of adult cardiomyocytes in ischemic pig hearts after plasmid-mediated rhVEGF165 gene transfer. Gene Ther 2002;9(24):1676-81
-
(2002)
Gene Ther
, vol.9
, Issue.24
, pp. 1676-1681
-
-
Laguens, R.1
Cabeza Meckert, P.2
Vera Janavel, G.3
-
53
-
-
0036897226
-
Comparison of protein with DNA therapy for chronic myocardial ischemia using fibroblast growth factor-2
-
Heilmann C, von Samson P, Schlegel K, et al. Comparison of protein with DNA therapy for chronic myocardial ischemia using fibroblast growth factor-2. Eur J Cardiothorac Surg 2002;22(6):957-64
-
(2002)
Eur J Cardiothorac Surg
, vol.22
, Issue.6
, pp. 957-964
-
-
Heilmann, C.1
Von Samson, P.2
Schlegel, K.3
-
54
-
-
0142185388
-
Gene therapy in cardiac surgery: Intramyocardial injection of naked plasmid DNA for chronic myocardial ischemia
-
Heilmann CA, Attmann T, Thiem A, et al. Gene therapy in cardiac surgery: intramyocardial injection of naked plasmid DNA for chronic myocardial ischemia. Eur J Cardiothorac Surg 2003;24(5):785-93
-
(2003)
Eur J Cardiothorac Surg
, vol.24
, Issue.5
, pp. 785-793
-
-
Heilmann, C.A.1
Attmann, T.2
Thiem, A.3
-
55
-
-
0037383667
-
Gene transfer of hepatocyte growth factor improves angiogenesis and function of chronic ischemic myocardium in canine heart
-
Ahmet I, Sawa Y, Yamaguchi T, Matsuda H. Gene transfer of hepatocyte growth factor improves angiogenesis and function of chronic ischemic myocardium in canine heart. Ann Thorac Surg 2003;75(4):1283-7
-
(2003)
Ann Thorac Surg
, vol.75
, Issue.4
, pp. 1283-1287
-
-
Ahmet, I.1
Sawa, Y.2
Yamaguchi, T.3
Matsuda, H.4
-
56
-
-
79955059149
-
Myocardial transfection with naked DNA plasmid encoding hepatocyte growth factor prevents the progression of heart failure in dogs
-
Rastogi S, Guerrero M, Wang M, et al. Myocardial transfection with naked DNA plasmid encoding hepatocyte growth factor prevents the progression of heart failure in dogs. Am J Physiol Heart Circ Physiol 2011;300(4):H1501-9
-
(2011)
Am J Physiol Heart Circ Physiol
, vol.300
, Issue.4
-
-
Rastogi, S.1
Guerrero, M.2
Wang, M.3
-
57
-
-
77953173235
-
Improvement of heart function in postinfarct heart failure swine models after hepatocyte growth factor gene transfer: Comparison of low-medium-and high-dose groups
-
Yang ZJ, Chen B, Sheng Z, et al. Improvement of heart function in postinfarct heart failure swine models after hepatocyte growth factor gene transfer: comparison of low-, medium-and high-dose groups. Mol Biol Rep 2010;37(4):2075-81
-
(2010)
Mol Biol Rep
, vol.37
, Issue.4
, pp. 2075-2081
-
-
Yang, Z.J.1
Chen, B.2
Sheng, Z.3
-
58
-
-
33746913545
-
Angiogenic and antifibrotic actions of hepatocyte growth factor improve cardiac dysfunction in porcine ischemic cardiomyopathy
-
Azuma J, Taniyama Y, Takeya Y, et al. Angiogenic and antifibrotic actions of hepatocyte growth factor improve cardiac dysfunction in porcine ischemic cardiomyopathy. Gene Ther 2006;13(16):1206-13
-
(2006)
Gene Ther
, vol.13
, Issue.16
, pp. 1206-1213
-
-
Azuma, J.1
Taniyama, Y.2
Takeya, Y.3
-
59
-
-
84874763067
-
An open-label dose escalation study to evaluate the safety of administration of nonviral stromal cell-derived factor-1 plasmid to treat symptomatic ischemic heart failure
-
Penn MS, Mendelsohn FO, Schaer GL, et al. An open-label dose escalation study to evaluate the safety of administration of nonviral stromal cell-derived factor-1 plasmid to treat symptomatic ischemic heart failure. Circ Res 2013;112(5):816-25
-
(2013)
Circ Res
, vol.112
, Issue.5
, pp. 816-825
-
-
Penn, M.S.1
Mendelsohn, F.O.2
Schaer, G.L.3
-
60
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126(4):663-76
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
61
-
-
84863629484
-
In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes
-
Qian L, Huang Y, Spencer CI, et al. In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes. Nature 2012;485(7400):593-8
-
(2012)
Nature
, vol.485
, Issue.7400
, pp. 593-598
-
-
Qian, L.1
Huang, Y.2
Spencer, C.I.3
-
62
-
-
84863626782
-
Heart repair by reprogramming non-myocytes with cardiac transcription factors
-
Song K, Nam YJ, Luo X, et al. Heart repair by reprogramming non-myocytes with cardiac transcription factors. Nature 2012;485(7400):599-604
-
(2012)
Nature
, vol.485
, Issue.7400
, pp. 599-604
-
-
Song, K.1
Nam, Y.J.2
Luo, X.3
-
63
-
-
84861642380
-
MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes
-
Jayawardena TM, Egemnazarov B, Finch EA, et al. MicroRNA-mediated in vitro and in vivo direct reprogramming of cardiac fibroblasts to cardiomyocytes. Circ Res 2012;110(11):1465-73
-
(2012)
Circ Res
, vol.110
, Issue.11
, pp. 1465-1473
-
-
Jayawardena, T.M.1
Egemnazarov, B.2
Finch, E.A.3
-
64
-
-
79953681886
-
Gene therapy strategies for cardiac electrical dysfunction
-
Greener I, Donahue JK. Gene therapy strategies for cardiac electrical dysfunction. J Mol Cell Cardiol 2011;50(5):759-65
-
(2011)
J Mol Cell Cardiol
, vol.50
, Issue.5
, pp. 759-765
-
-
Greener, I.1
Donahue, J.K.2
-
65
-
-
84856087307
-
Connexin gene transfer preserves conduction velocity and prevents atrial fibrillation
-
Igarashi T, Finet JE, Takeuchi A, et al. Connexin gene transfer preserves conduction velocity and prevents atrial fibrillation. Circulation 2012;125(2):216-25
-
(2012)
Circulation
, vol.125
, Issue.2
, pp. 216-225
-
-
Igarashi, T.1
Finet, J.E.2
Takeuchi, A.3
-
66
-
-
80054116111
-
Connexin 43 gene therapy prevents persistent atrial fibrillation in a porcine model
-
Bikou O, Thomas D, Trappe K, et al. Connexin 43 gene therapy prevents persistent atrial fibrillation in a porcine model. Cardiovasc Res 2011;92(2):218-25
-
(2011)
Cardiovasc Res
, vol.92
, Issue.2
, pp. 218-225
-
-
Bikou, O.1
Thomas, D.2
Trappe, K.3
-
67
-
-
77953231186
-
Selective molecular potassium channel blockade prevents atrial fibrillation
-
Amit G, Kikuchi K, Greener ID, et al. Selective molecular potassium channel blockade prevents atrial fibrillation. Circulation 2010;121(21):2263-70
-
(2010)
Circulation
, vol.121
, Issue.21
, pp. 2263-2270
-
-
Amit, G.1
Kikuchi, K.2
Greener, I.D.3
-
68
-
-
0021883888
-
The effect of selective breeding on the development of coronary atherosclerosis in WHHL rabbits, An animal model for familial hypercholesterolemia
-
Watanabe Y, Ito T, Shiomi M. The effect of selective breeding on the development of coronary atherosclerosis in WHHL rabbits. An animal model for familial hypercholesterolemia. Atherosclerosis 1985;56(1):71-9
-
(1985)
Atherosclerosis
, vol.56
, Issue.1
, pp. 71-79
-
-
Watanabe, Y.1
Ito, T.2
Shiomi, M.3
-
69
-
-
0024231872
-
Genetically determined hypercholesterolemia in a rhesus monkey family due to a deficiency of the LDL receptor
-
Scanu AM, Khalil A, Neven L, et al. Genetically determined hypercholesterolemia in a rhesus monkey family due to a deficiency of the LDL receptor. J Lipid Res 1988;29(12):1671-81
-
(1988)
J Lipid Res
, vol.29
, Issue.12
, pp. 1671-1681
-
-
Scanu, A.M.1
Khalil, A.2
Neven, L.3
-
70
-
-
0028345073
-
Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice
-
Ishibashi S, Goldstein JL, Brown MS, et al. Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice. J Clin Invest 1994;93(5):1885-93
-
(1994)
J Clin Invest
, vol.93
, Issue.5
, pp. 1885-1893
-
-
Ishibashi, S.1
Goldstein, J.L.2
Brown, M.S.3
-
71
-
-
0038442874
-
Intravenous gene therapy for familial hypercholesterolemia using ligand-facilitated transfer of a liposome:LDL receptor gene complex
-
Shichiri M, Tanaka A, Hirata Y. Intravenous gene therapy for familial hypercholesterolemia using ligand-facilitated transfer of a liposome:LDL receptor gene complex. Gene Ther 2003;10(9):827-31
-
(2003)
Gene Ther
, vol.10
, Issue.9
, pp. 827-831
-
-
Shichiri, M.1
Tanaka, A.2
Hirata, Y.3
-
72
-
-
34247221442
-
Total arterial coronary revascularization using arterial bypass circle with multiple inflows
-
El Oakley RM, Al Habib HF. Total arterial coronary revascularization using arterial bypass circle with multiple inflows. Ann Thorac Surg 2007;83(5):1911-12
-
(2007)
Ann Thorac Surg
, vol.83
, Issue.5
, pp. 1911-1912
-
-
El Oakley, R.M.1
Al Habib, H.F.2
-
73
-
-
84866325705
-
Edifoligide and long-term outcomes after coronary artery bypass grafting: PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) 5-year results
-
Lopes RD, Williams JB, Mehta RH, et al. Edifoligide and long-term outcomes after coronary artery bypass grafting: PRoject of Ex-vivo Vein graft ENgineering via Transfection IV (PREVENT IV) 5-year results. Am Heart J 2012;164(3):379-86 e1
-
(2012)
Am Heart J
, vol.164
, Issue.3
-
-
Lopes, R.D.1
Williams, J.B.2
Mehta, R.H.3
-
74
-
-
4444295588
-
Antimonocyte chemoattractant protein-1 gene therapy reduces experimental in-stent restenosis in hypercholesterolemic rabbits and monkeys
-
Ohtani K, Usui M, Nakano K, et al. Antimonocyte chemoattractant protein-1 gene therapy reduces experimental in-stent restenosis in hypercholesterolemic rabbits and monkeys. Gene Ther 2004;11(16):1273-82
-
(2004)
Gene Ther
, vol.11
, Issue.16
, pp. 1273-1282
-
-
Ohtani, K.1
Usui, M.2
Nakano, K.3
-
75
-
-
84874346554
-
Gene therapy clinical trials worldwide to 2012-an update
-
Ginn SL, Alexander IE, Edelstein ML, et al. Gene therapy clinical trials worldwide to 2012-an update. J Gene Med 2013;15(2):65-77
-
(2013)
J Gene Med
, vol.15
, Issue.2
, pp. 65-77
-
-
Ginn, S.L.1
Alexander, I.E.2
Edelstein, M.L.3
-
76
-
-
1842533449
-
Insertional oncogenesis in gene therapy: How much of a risk?
-
Sadelain M. Insertional oncogenesis in gene therapy: how much of a risk? Gene Ther 2004;11(7):569-73
-
(2004)
Gene Ther
, vol.11
, Issue.7
, pp. 569-573
-
-
Sadelain, M.1
-
78
-
-
0142084745
-
LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1
-
Hacein-Bey-Abina S, Von Kalle C, Schmidt M, et al. LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1. Science 2003;302(5644):415-19
-
(2003)
Science
, vol.302
, Issue.5644
, pp. 415-419
-
-
Hacein-Bey-Abina, S.1
Von Kalle, C.2
Schmidt, M.3
-
79
-
-
0034724857
-
Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease
-
Cavazzana-Calvo M, Hacein-Bey S, de Saint Basile G, et al. Gene therapy of human severe combined immunodeficiency (SCID)-X1 disease. Science 2000;288(5466):669-72
-
(2000)
Science
, vol.288
, Issue.5466
, pp. 669-672
-
-
Cavazzana-Calvo, M.1
Hacein-Bey, S.2
De Saint Basile, G.3
-
80
-
-
0042738935
-
Occurrence of leukaemia following gene therapy of X-linked SCID
-
Kohn DB, Sadelain M, Glorioso JC. Occurrence of leukaemia following gene therapy of X-linked SCID. Nat Rev Cancer 2003;3(7):477-88
-
(2003)
Nat Rev Cancer
, vol.3
, Issue.7
, pp. 477-488
-
-
Kohn, D.B.1
Sadelain, M.2
Glorioso, J.C.3
-
81
-
-
0037162715
-
HIV-1 integration in the human genome favors active genes and local hotspots
-
Schroder AR, Shinn P, Chen H, et al. HIV-1 integration in the human genome favors active genes and local hotspots. Cell 2002;110(4):521-9
-
(2002)
Cell
, vol.110
, Issue.4
, pp. 521-529
-
-
Schroder, A.R.1
Shinn, P.2
Chen, H.3
-
82
-
-
0035794637
-
The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation
-
Jordan A, Defechereux P, Verdin E. The site of HIV-1 integration in the human genome determines basal transcriptional activity and response to Tat transactivation. EMBO J 2001;20(7):1726-38
-
(2001)
EMBO J
, vol.20
, Issue.7
, pp. 1726-1738
-
-
Jordan, A.1
Defechereux, P.2
Verdin, E.3
-
83
-
-
10744233606
-
Chance or necessity? Insertional mutagenesis in gene therapy and its consequences
-
Baum C, von Kalle C, Staal FJ, et al. Chance or necessity? Insertional mutagenesis in gene therapy and its consequences. Mol Ther 2004;9(1):5-13
-
(2004)
Mol Ther
, vol.9
, Issue.1
, pp. 5-13
-
-
Baum, C.1
Von Kalle, C.2
Staal, F.J.3
-
84
-
-
27544459099
-
Gene therapy bio-safety: Scientific and regulatory issues
-
Gonin P, Buchholz CJ, Pallardy M, Mezzina M. Gene therapy bio-safety: scientific and regulatory issues. Gene Ther 2005;12(Suppl 1):S146-52
-
(2005)
Gene Ther
, vol.12
, Issue.SUPPL. 1
-
-
Gonin, P.1
Buchholz, C.J.2
Pallardy, M.3
Mezzina, M.4
-
85
-
-
33751251058
-
Gene transfer in humans using a conditionally replicating lentiviral vector
-
Levine BL, Humeau LM, Boyer J, et al. Gene transfer in humans using a conditionally replicating lentiviral vector. Proc Natl Acad Sci USA 2006;103(46):17372-7
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, Issue.46
, pp. 17372-17377
-
-
Levine, B.L.1
Humeau, L.M.2
Boyer, J.3
-
86
-
-
33846160971
-
Lentiviral vectors ready for prime-time
-
Kohn DB. Lentiviral vectors ready for prime-time. Nat Biotechnol 2007;25(1):65-6
-
(2007)
Nat Biotechnol
, vol.25
, Issue.1
, pp. 65-66
-
-
Kohn, D.B.1
-
87
-
-
33751183069
-
Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects
-
Mortellaro A, Hernandez RJ, Guerrini MM, et al. Ex vivo gene therapy with lentiviral vectors rescues adenosine deaminase (ADA)-deficient mice and corrects their immune and metabolic defects. Blood 2006;108(9):2979-88
-
(2006)
Blood
, vol.108
, Issue.9
, pp. 2979-2988
-
-
Mortellaro, A.1
Hernandez, R.J.2
Guerrini, M.M.3
-
88
-
-
26644444774
-
Arteriogenic gene therapy in patients with unreconstructable critical limb ischemia: A randomized, placebo-controlled clinical trial of adenovirus 5-delivered fibroblast growth factor-4
-
Matyas L, Schulte KL, Dormandy JA, et al. Arteriogenic gene therapy in patients with unreconstructable critical limb ischemia: a randomized, placebo-controlled clinical trial of adenovirus 5-delivered fibroblast growth factor-4. Hum Gene Ther 2005;16(10):1202-11
-
(2005)
Hum Gene Ther
, vol.16
, Issue.10
, pp. 1202-1211
-
-
Matyas, L.1
Schulte, K.L.2
Dormandy, J.A.3
-
89
-
-
50949121232
-
Therapeutic angiogenesis for critical limb ischemia: Microvascular therapies coming of age
-
Tongers J, Roncalli JG, Losordo DW. Therapeutic angiogenesis for critical limb ischemia: microvascular therapies coming of age. Circulation 2008;118(1):9-16
-
(2008)
Circulation
, vol.118
, Issue.1
, pp. 9-16
-
-
Tongers, J.1
Roncalli, J.G.2
Losordo, D.W.3
-
90
-
-
0142089747
-
Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer
-
Raper SE, Chirmule N, Lee FS, et al. Fatal systemic inflammatory response syndrome in a ornithine transcarbamylase deficient patient following adenoviral gene transfer. Mol Genet Metab 2003;80(1-2):148-58
-
(2003)
Mol Genet Metab
, vol.80
, Issue.1-2
, pp. 148-158
-
-
Raper, S.E.1
Chirmule, N.2
Lee, F.S.3
-
91
-
-
84883268937
-
Immune responses to AAV vectors: Overcoming barriers to successful gene therapy
-
Mingozzi F, High KA. Immune responses to AAV vectors: overcoming barriers to successful gene therapy. Blood 2013;122(1):23-36
-
(2013)
Blood
, vol.122
, Issue.1
, pp. 23-36
-
-
Mingozzi, F.1
High, K.A.2
-
92
-
-
79959932534
-
Immune responses to AAV in clinical trials
-
Mingozzi F, High KA. Immune responses to AAV in clinical trials. Curr Gene Ther 2011;11(4):321-30
-
(2011)
Curr Gene Ther
, vol.11
, Issue.4
, pp. 321-330
-
-
Mingozzi, F.1
High, K.A.2
-
93
-
-
35349027352
-
Immune responses to AAV in clinical trials
-
Mingozzi F, High KA. Immune responses to AAV in clinical trials. Curr Gene Ther 2007;7(5):316-24
-
(2007)
Curr Gene Ther
, vol.7
, Issue.5
, pp. 316-324
-
-
Mingozzi, F.1
High, K.A.2
-
94
-
-
33745606715
-
Multiyear therapeutic benefit of AAV serotypes 2, 6, and 8 delivering factor VIII to hemophilia A mice and dogs
-
Jiang H, Lillicrap D, Patarroyo-White S, et al. Multiyear therapeutic benefit of AAV serotypes 2, 6, and 8 delivering factor VIII to hemophilia A mice and dogs. Blood 2006;108(1):107-15
-
(2006)
Blood
, vol.108
, Issue.1
, pp. 107-115
-
-
Jiang, H.1
Lillicrap, D.2
Patarroyo-White, S.3
-
95
-
-
18244394301
-
Regional intravascular delivery of AAV-2-F.IX to skeletal muscle achieves long-term correction of hemophilia B in a large animal model
-
Arruda VR, Stedman HH, Nichols TC, et al. Regional intravascular delivery of AAV-2-F.IX to skeletal muscle achieves long-term correction of hemophilia B in a large animal model. Blood 2005;105(9):3458-64
-
(2005)
Blood
, vol.105
, Issue.9
, pp. 3458-3464
-
-
Arruda, V.R.1
Stedman, H.H.2
Nichols, T.C.3
-
96
-
-
17444387438
-
Long-term correction of canine hemophilia B by gene transfer of blood coagulation factor IX mediated by adeno-associated viral vector
-
Herzog RW, Yang EY, Couto LB, et al. Long-term correction of canine hemophilia B by gene transfer of blood coagulation factor IX mediated by adeno-associated viral vector. Nat Med 1999;5(1):56-63
-
(1999)
Nat Med
, vol.5
, Issue.1
, pp. 56-63
-
-
Herzog, R.W.1
Yang, E.Y.2
Couto, L.B.3
-
97
-
-
21244441929
-
Immune responses to adeno-associated virus vectors
-
Zaiss AK, Muruve DA. Immune responses to adeno-associated virus vectors. Curr Gene Ther 2005;5(3):323-31
-
(2005)
Curr Gene Ther
, vol.5
, Issue.3
, pp. 323-331
-
-
Zaiss, A.K.1
Muruve, D.A.2
-
98
-
-
35348984094
-
Immune responses to adenovirus and adeno-associated vectors used for gene therapy of brain diseases: The role of immunological synapses in understanding the cell biology of neuroimmune interactions
-
Lowenstein PR, Mandel RJ, Xiong WD, et al. Immune responses to adenovirus and adeno-associated vectors used for gene therapy of brain diseases: the role of immunological synapses in understanding the cell biology of neuroimmune interactions. Curr Gene Ther 2007;7(5):347-60
-
(2007)
Curr Gene Ther
, vol.7
, Issue.5
, pp. 347-360
-
-
Lowenstein, P.R.1
Mandel, R.J.2
Xiong, W.D.3
-
99
-
-
44449114156
-
Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure
-
Hajjar RJ, Zsebo K, Deckelbaum L, et al. Design of a phase 1/2 trial of intracoronary administration of AAV1/SERCA2a in patients with heart failure. J Card Fail 2008;14(5):355-67
-
(2008)
J Card Fail
, vol.14
, Issue.5
, pp. 355-367
-
-
Hajjar, R.J.1
Zsebo, K.2
Deckelbaum, L.3
-
100
-
-
58849086758
-
Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses
-
Calcedo R, Vandenberghe LH, Gao G, et al. Worldwide epidemiology of neutralizing antibodies to adeno-associated viruses. J Infect Dis 2009;199(3):381-90
-
(2009)
J Infect Dis
, vol.199
, Issue.3
, pp. 381-390
-
-
Calcedo, R.1
Vandenberghe, L.H.2
Gao, G.3
-
101
-
-
80455155171
-
A 10 patient case report on the impact of plasmapheresis upon neutralizing factors against adeno-associated virus (AAV) types 1, 2, 6, and 8
-
Monteilhet V, Saheb S, Boutin S, et al. A 10 patient case report on the impact of plasmapheresis upon neutralizing factors against adeno-associated virus (AAV) types 1, 2, 6, and 8. Mol Ther 2011;19(11):2084-91
-
(2011)
Mol Ther
, vol.19
, Issue.11
, pp. 2084-2091
-
-
Monteilhet, V.1
Saheb, S.2
Boutin, S.3
-
102
-
-
84863480768
-
Pharmacological modulation of humoral immunity in a nonhuman primate model of AAV gene transfer for hemophilia B
-
Mingozzi F, Chen Y, Murphy SL, et al. Pharmacological modulation of humoral immunity in a nonhuman primate model of AAV gene transfer for hemophilia B. Mol Ther 2012;20(7):1410-16
-
(2012)
Mol Ther
, vol.20
, Issue.7
, pp. 1410-1416
-
-
Mingozzi, F.1
Chen, Y.2
Murphy, S.L.3
-
104
-
-
84873337445
-
Minimizing the inhibitory effect of neutralizing antibody for efficient gene expression in the liver with adeno-associated virus 8 vectors
-
Mimuro J, Mizukami H, Hishikawa S, et al. Minimizing the inhibitory effect of neutralizing antibody for efficient gene expression in the liver with adeno-associated virus 8 vectors. Mol Ther 2013;21(2):318-23
-
(2013)
Mol Ther
, vol.21
, Issue.2
, pp. 318-323
-
-
Mimuro, J.1
Mizukami, H.2
Hishikawa, S.3
-
105
-
-
35148855074
-
An inventory of shedding data from clinical gene therapy trials
-
Schenk-Braat EA, van Mierlo MM, Wagemaker G, et al. An inventory of shedding data from clinical gene therapy trials. J Gene Med 2007;9(10):910-21
-
(2007)
J Gene Med
, vol.9
, Issue.10
, pp. 910-921
-
-
Schenk-Braat, E.A.1
Van Mierlo, M.M.2
Wagemaker, G.3
-
106
-
-
33644820684
-
Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response
-
Manno CS, Pierce GF, Arruda VR, et al. Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response. Nat Med 2006;12(3):342-7
-
(2006)
Nat Med
, vol.12
, Issue.3
, pp. 342-347
-
-
Manno, C.S.1
Pierce, G.F.2
Arruda, V.R.3
-
107
-
-
0032578961
-
Gene therapy for myocardial angiogenesis: Initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia
-
Losordo DW, Vale PR, Symes JF, et al. Gene therapy for myocardial angiogenesis: initial clinical results with direct myocardial injection of phVEGF165 as sole therapy for myocardial ischemia. Circulation 1998;98(25):2800-4
-
(1998)
Circulation
, vol.98
, Issue.25
, pp. 2800-2804
-
-
Losordo, D.W.1
Vale, P.R.2
Symes, J.F.3
-
108
-
-
0033520056
-
Angiogenesis gene therapy: Phase i assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease
-
Rosengart TK, Lee LY, Patel SR, et al. Angiogenesis gene therapy: phase I assessment of direct intramyocardial administration of an adenovirus vector expressing VEGF121 cDNA to individuals with clinically significant severe coronary artery disease. Circulation 1999;100(5):468-74
-
(1999)
Circulation
, vol.100
, Issue.5
, pp. 468-474
-
-
Rosengart, T.K.1
Lee, L.Y.2
Patel, S.R.3
-
109
-
-
84860350915
-
AAV6.betaARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model
-
Raake PW, Schlegel P, Ksienzyk J, et al. AAV6.betaARKct cardiac gene therapy ameliorates cardiac function and normalizes the catecholaminergic axis in a clinically relevant large animal heart failure model. Eur Heart J 2013;34(19):1437-47
-
(2013)
Eur Heart J
, vol.34
, Issue.19
, pp. 1437-1447
-
-
Raake, P.W.1
Schlegel, P.2
Ksienzyk, J.3
-
110
-
-
80054955037
-
Gene delivery methods in cardiac gene therapy
-
Ishikawa K, Tilemann L, Fish K, Hajjar RJ. Gene delivery methods in cardiac gene therapy. J Gene Med 2011;13(10):566-72
-
(2011)
J Gene Med
, vol.13
, Issue.10
, pp. 566-572
-
-
Ishikawa, K.1
Tilemann, L.2
Fish, K.3
Hajjar, R.J.4
-
111
-
-
84857785617
-
Concomitant intravenous nitroglycerin with intracoronary delivery of AAV1. SERCA2a enhances gene transfer in porcine hearts
-
Karakikes I, Hadri L, Rapti K, et al. Concomitant intravenous nitroglycerin with intracoronary delivery of AAV1. SERCA2a enhances gene transfer in porcine hearts. Mol Ther 2012;20(3):565-71
-
(2012)
Mol Ther
, vol.20
, Issue.3
, pp. 565-571
-
-
Karakikes, I.1
Hadri, L.2
Rapti, K.3
-
112
-
-
34247128721
-
Non-invasive imaging of firefly luciferase reporter gene expression using bioluminescence imaging in human prostate cancer models
-
Li H, Li JZ, Helm GA, Pan D. Non-invasive imaging of firefly luciferase reporter gene expression using bioluminescence imaging in human prostate cancer models. Biotechnol Appl Biochem 2007;46(Pt 4):179-84
-
(2007)
Biotechnol Appl Biochem
, vol.46
, Issue.PART 4
, pp. 179-184
-
-
Li, H.1
Li, J.Z.2
Helm, G.A.3
Pan, D.4
-
113
-
-
0028580734
-
Wavelength mutations and posttranslational autoxidation of green fluorescent protein
-
Heim R, Prasher DC, Tsien RY. Wavelength mutations and posttranslational autoxidation of green fluorescent protein. Proc Natl Acad Sci USA 1994;91(26):12501-4
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, Issue.26
, pp. 12501-12504
-
-
Heim, R.1
Prasher, D.C.2
Tsien, R.Y.3
-
114
-
-
0034710874
-
Visualizing gene expression by whole-body fluorescence imaging
-
Yang M, Baranov E, Moossa AR, et al. Visualizing gene expression by whole-body fluorescence imaging. Proc Natl Acad Sci USA 2000;97(22):12278-82
-
(2000)
Proc Natl Acad Sci USA
, vol.97
, Issue.22
, pp. 12278-12282
-
-
Yang, M.1
Baranov, E.2
Moossa, A.R.3
-
115
-
-
34247342742
-
Whole-body imaging with fluorescent proteins
-
Hoffman RM, Yang M. Whole-body imaging with fluorescent proteins. Nat Protoc 2006;1(3):1429-38
-
(2006)
Nat Protoc
, vol.1
, Issue.3
, pp. 1429-1438
-
-
Hoffman, R.M.1
Yang, M.2
-
116
-
-
58149399456
-
Fluorescence diffuse tomography for detection of red fluorescent protein expressed tumors in small animals
-
Turchin IV, Kamensky VA, Plehanov VI, et al. Fluorescence diffuse tomography for detection of red fluorescent protein expressed tumors in small animals. J Biomed Opt 2008;13(4):041310
-
(2008)
J Biomed Opt
, vol.13
, Issue.4
, pp. 041310
-
-
Turchin, I.V.1
Kamensky, V.A.2
Plehanov, V.I.3
-
117
-
-
0037983399
-
Fluorescence imaging with near-infrared light: New technological advances that enable in vivo molecular imaging
-
Ntziachristos V, Bremer C, Weissleder R. Fluorescence imaging with near-infrared light: new technological advances that enable in vivo molecular imaging. Eur Radiol 2003;13(1):195-208
-
(2003)
Eur Radiol
, vol.13
, Issue.1
, pp. 195-208
-
-
Ntziachristos, V.1
Bremer, C.2
Weissleder, R.3
-
118
-
-
0029939559
-
Chemistries and colors of bioluminescent reactions: A review
-
Hastings JW. Chemistries and colors of bioluminescent reactions: a review. Gene 1996;173(1 Spec No):5-11
-
(1996)
Gene
, vol.173
, Issue.1 SPEC. NO.
, pp. 5-11
-
-
Hastings, J.W.1
-
119
-
-
58149397222
-
Bioluminescence: Imaging modality for in vitro and in vivo gene expression
-
Sadikot RT, Blackwell TS. Bioluminescence: imaging modality for in vitro and in vivo gene expression. Methods Mol Biol 2008;477:383-94
-
(2008)
Methods Mol Biol
, vol.477
, pp. 383-394
-
-
Sadikot, R.T.1
Blackwell, T.S.2
-
120
-
-
0037046190
-
Optical imaging of cardiac reporter gene expression in living rats
-
Wu JC, Inubushi M, Sundaresan G, Schelbert HR, Gambhir SS. Optical imaging of cardiac reporter gene expression in living rats. Circulation 2002;105(14):1631-4
-
(2002)
Circulation
, vol.105
, Issue.14
, pp. 1631-1634
-
-
Wu, J.C.1
Inubushi, M.2
Sundaresan, G.3
Schelbert, H.R.4
Gambhir, S.S.5
-
121
-
-
4043081927
-
Molecular imaging of the kinetics of vascular endothelial growth factor gene expression in ischemic myocardium
-
Wu JC, Chen IY, Wang Y, et al. Molecular imaging of the kinetics of vascular endothelial growth factor gene expression in ischemic myocardium. Circulation 2004;110(6):685-91
-
(2004)
Circulation
, vol.110
, Issue.6
, pp. 685-691
-
-
Wu, J.C.1
Chen, I.Y.2
Wang, Y.3
-
122
-
-
28444464203
-
Positron emission tomography reporter gene imaging in the myocardium: For monitoring of angiogenic gene therapy in ischemic heart disease
-
Inubushi M, Tamaki N. Positron emission tomography reporter gene imaging in the myocardium: for monitoring of angiogenic gene therapy in ischemic heart disease. J Card Surg 2005;20(6):S20-4
-
(2005)
J Card Surg
, vol.20
, Issue.6
-
-
Inubushi, M.1
Tamaki, N.2
-
123
-
-
16544372457
-
PET of cardiac transgene expression: Comparison of 2 approaches based on herpesviral thymidine kinase reporter gene
-
Miyagawa M, Anton M, Haubner R, et al. PET of cardiac transgene expression: comparison of 2 approaches based on herpesviral thymidine kinase reporter gene. J Nucl Med 2004;45(11):1917-23
-
(2004)
J Nucl Med
, vol.45
, Issue.11
, pp. 1917-1923
-
-
Miyagawa, M.1
Anton, M.2
Haubner, R.3
-
124
-
-
33745143956
-
Robust systemic transduction with AAV9 vectors in mice: Efficient global cardiac gene transfer superior to that of AAV8
-
Inagaki K, Fuess S, Storm TA, et al. Robust systemic transduction with AAV9 vectors in mice: efficient global cardiac gene transfer superior to that of AAV8. Mol Ther 2006;14(1):45-53
-
(2006)
Mol Ther
, vol.14
, Issue.1
, pp. 45-53
-
-
Inagaki, K.1
Fuess, S.2
Storm, T.A.3
-
125
-
-
56749102970
-
Percutaneous transendocardial delivery of self-complementary adeno-associated virus 6 achieves global cardiac gene transfer in canines
-
Bish LT, Sleeper MM, Brainard B, et al. Percutaneous transendocardial delivery of self-complementary adeno-associated virus 6 achieves global cardiac gene transfer in canines. Mol Ther 2008;16(12):1953-9
-
(2008)
Mol Ther
, vol.16
, Issue.12
, pp. 1953-1959
-
-
Bish, L.T.1
Sleeper, M.M.2
Brainard, B.3
-
126
-
-
44349170706
-
Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection
-
Zincarelli C, Soltys S, Rengo G, Rabinowitz JE. Analysis of AAV serotypes 1-9 mediated gene expression and tropism in mice after systemic injection. Mol Ther 2008;16(6):1073-80
-
(2008)
Mol Ther
, vol.16
, Issue.6
, pp. 1073-1080
-
-
Zincarelli, C.1
Soltys, S.2
Rengo, G.3
Rabinowitz, J.E.4
-
127
-
-
33645064807
-
Improved cardiac gene transfer by transcriptional and transductional targeting of adeno-associated viral vectors
-
Muller OJ, Leuchs B, Pleger ST, et al. Improved cardiac gene transfer by transcriptional and transductional targeting of adeno-associated viral vectors. Cardiovasc Res 2006;70(1):70-8
-
(2006)
Cardiovasc Res
, vol.70
, Issue.1
, pp. 70-78
-
-
Muller, O.J.1
Leuchs, B.2
Pleger, S.T.3
-
128
-
-
79951510234
-
MicroRNA122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors
-
Geisler A, Jungmann A, Kurreck J, et al. microRNA122-regulated transgene expression increases specificity of cardiac gene transfer upon intravenous delivery of AAV9 vectors. Gene Ther 2011;18(2):199-209
-
(2011)
Gene Ther
, vol.18
, Issue.2
, pp. 199-209
-
-
Geisler, A.1
Jungmann, A.2
Kurreck, J.3
-
129
-
-
59049097977
-
Myocardial adeno-associated virus serotype 6-betaARKct gene therapy improves cardiac function and normalizes the neurohormonal axis in chronic heart failure
-
Rengo G, Lymperopoulos A, Zincarelli C, et al. Myocardial adeno-associated virus serotype 6-betaARKct gene therapy improves cardiac function and normalizes the neurohormonal axis in chronic heart failure. Circulation 2009;119(1):89-98
-
(2009)
Circulation
, vol.119
, Issue.1
, pp. 89-98
-
-
Rengo, G.1
Lymperopoulos, A.2
Zincarelli, C.3
-
130
-
-
0019982539
-
Decreased catecholamine sensitivity and beta-adrenergic-receptor density in failing human hearts
-
Bristow MR, Ginsburg R, Minobe W, et al. Decreased catecholamine sensitivity and beta-adrenergic-receptor density in failing human hearts. N Engl J Med 1982;307(4):205-11
-
(1982)
N Engl J Med
, vol.307
, Issue.4
, pp. 205-211
-
-
Bristow, M.R.1
Ginsburg, R.2
Minobe, W.3
-
131
-
-
0030798818
-
Mechanism of beta-adrenergic receptor desensitization in cardiac hypertrophy is increased beta-adrenergic receptor kinase
-
Choi DJ, Koch WJ, Hunter JJ, Rockman HA. Mechanism of beta-adrenergic receptor desensitization in cardiac hypertrophy is increased beta-adrenergic receptor kinase. J Biol Chem 1997;272(27):17223-9
-
(1997)
J Biol Chem
, vol.272
, Issue.27
, pp. 17223-17229
-
-
Choi, D.J.1
Koch, W.J.2
Hunter, J.J.3
Rockman, H.A.4
-
132
-
-
0029798741
-
Activation of beta-adrenergic receptor kinase during myocardial ischemia
-
Ungerer M, Kessebohm K, Kronsbein K, et al. Activation of beta-adrenergic receptor kinase during myocardial ischemia. Circ Res 1996;79(3):455-60
-
(1996)
Circ Res
, vol.79
, Issue.3
, pp. 455-460
-
-
Ungerer, M.1
Kessebohm, K.2
Kronsbein, K.3
-
133
-
-
0031000256
-
G-protein-coupled receptor kinase activity is increased in hypertension
-
Gros R, Benovic JL, Tan CM, Feldman RD. G-protein-coupled receptor kinase activity is increased in hypertension. J Clin Invest 1997;99(9):2087-93
-
(1997)
J Clin Invest
, vol.99
, Issue.9
, pp. 2087-2093
-
-
Gros, R.1
Benovic, J.L.2
Tan, C.M.3
Feldman, R.D.4
-
134
-
-
0032499733
-
Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice
-
Rockman HA, Chien KR, Choi DJ, et al. Expression of a beta-adrenergic receptor kinase 1 inhibitor prevents the development of myocardial failure in gene-targeted mice. Proc Natl Acad Sci USA 1998;95(12):7000-5
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, Issue.12
, pp. 7000-7005
-
-
Rockman, H.A.1
Chien, K.R.2
Choi, D.J.3
-
135
-
-
0035826710
-
Cardiac beta ARK1 inhibition prolongs survival and augments beta blocker therapy in a mouse model of severe heart failure
-
Harding VB, Jones LR, Lefkowitz RJ, et al. Cardiac beta ARK1 inhibition prolongs survival and augments beta blocker therapy in a mouse model of severe heart failure. Proc Natl Acad Sci USA 2001;98(10):5809-14
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, Issue.10
, pp. 5809-5814
-
-
Harding, V.B.1
Jones, L.R.2
Lefkowitz, R.J.3
-
136
-
-
0032540893
-
Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice
-
Rockman HA, Choi DJ, Akhter SA, et al. Control of myocardial contractile function by the level of beta-adrenergic receptor kinase 1 in gene-targeted mice. J Biol Chem 1998;273(29):18180-4
-
(1998)
J Biol Chem
, vol.273
, Issue.29
, pp. 18180-18184
-
-
Rockman, H.A.1
Choi, D.J.2
Akhter, S.A.3
-
137
-
-
84879252168
-
Myocardial ablation of G protein-coupled receptor kinase 2 (GRK2) decreases ischemia/reperfusion Injury through an anti-intrinsic apoptotic pathway
-
Fan Q, Chen M, Zuo L, et al. Myocardial ablation of G protein-coupled receptor kinase 2 (GRK2) decreases ischemia/reperfusion Injury through an anti-intrinsic apoptotic pathway. PLoS One 2013;8(6):e66234
-
(2013)
PLoS One
, vol.8
, Issue.6
-
-
Fan, Q.1
Chen, M.2
Zuo, L.3
|