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Volumn 46, Issue 6, 2013, Pages 552-560

The versatile role of gliadin peptides in celiac disease

Author keywords

Celiac disease; Endosome; Gliadin; Immune response

Indexed keywords

AUTOANTIBODY; GLIADIN; GLUTEN; PEPTIDE;

EID: 84891721240     PISSN: 00099120     EISSN: 18732933     Source Type: Journal    
DOI: 10.1016/j.clinbiochem.2012.10.038     Document Type: Review
Times cited : (26)

References (90)
  • 1
    • 20144388176 scopus 로고    scopus 로고
    • The prevalence of celiac disease in average-risk and at-risk Western European populations: a systematic review
    • Dube C., Rostom A., Sy R., Cranney A., Saloojee N., Garritty C., et al. The prevalence of celiac disease in average-risk and at-risk Western European populations: a systematic review. Gastroenterology 2005, 128:S57-S67.
    • (2005) Gastroenterology , vol.128
    • Dube, C.1    Rostom, A.2    Sy, R.3    Cranney, A.4    Saloojee, N.5    Garritty, C.6
  • 2
    • 78249280263 scopus 로고    scopus 로고
    • Are we not over-estimating the prevalence of coeliac disease in the general population?
    • Biagi F., Klersy C., Balduzzi D., Corazza G.R. Are we not over-estimating the prevalence of coeliac disease in the general population?. Ann Med 2010, 42:557-561.
    • (2010) Ann Med , vol.42 , pp. 557-561
    • Biagi, F.1    Klersy, C.2    Balduzzi, D.3    Corazza, G.R.4
  • 4
  • 5
    • 0033364256 scopus 로고    scopus 로고
    • The histopathology of coeliac disease: time for a standardized report scheme for pathologists
    • Oberhuber G., Granditsch G., Vogelsang H. The histopathology of coeliac disease: time for a standardized report scheme for pathologists. Eur J Gastroenterol Hepatol 1999, 11:1185-1194.
    • (1999) Eur J Gastroenterol Hepatol , vol.11 , pp. 1185-1194
    • Oberhuber, G.1    Granditsch, G.2    Vogelsang, H.3
  • 7
    • 59849109225 scopus 로고    scopus 로고
    • Presentation and long-term follow-up of refractory celiac disease: comparison of type I with type II
    • Malamut G., Afchain P., Verkarre V., Lecomte T., Amiot A., Damotte D., et al. Presentation and long-term follow-up of refractory celiac disease: comparison of type I with type II. Gastroenterology 2009, 136:81-90.
    • (2009) Gastroenterology , vol.136 , pp. 81-90
    • Malamut, G.1    Afchain, P.2    Verkarre, V.3    Lecomte, T.4    Amiot, A.5    Damotte, D.6
  • 8
    • 78649444935 scopus 로고    scopus 로고
    • Enteropathy-associated T-cell lymphoma: a review on clinical presentation, diagnosis, therapeutic strategies and perspectives
    • Chandesris M.O., Malamut G., Verkarre V., Meresse B., Macintyre E., Delarue R., et al. Enteropathy-associated T-cell lymphoma: a review on clinical presentation, diagnosis, therapeutic strategies and perspectives. Gastroenterol Clin Biol 2010, 34:590-605.
    • (2010) Gastroenterol Clin Biol , vol.34 , pp. 590-605
    • Chandesris, M.O.1    Malamut, G.2    Verkarre, V.3    Meresse, B.4    Macintyre, E.5    Delarue, R.6
  • 12
    • 84858653535 scopus 로고    scopus 로고
    • How I treat enteropathy-associated T-cell lymphoma
    • Di Sabatino A., Biagi F., Gobbi P.G., Corazza G.R. How I treat enteropathy-associated T-cell lymphoma. Blood 2012, 119:2458-2468.
    • (2012) Blood , vol.119 , pp. 2458-2468
    • Di Sabatino, A.1    Biagi, F.2    Gobbi, P.G.3    Corazza, G.R.4
  • 13
    • 0030877557 scopus 로고    scopus 로고
    • Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls
    • Molberg O., Kett K., Scott H., Thorsby E., Sollid L.M., Lundin K.E. Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls. Scand J Immunol 1997, 46:103-109.
    • (1997) Scand J Immunol , vol.46 , pp. 103-109
    • Molberg, O.1    Kett, K.2    Scott, H.3    Thorsby, E.4    Sollid, L.M.5    Lundin, K.E.6
  • 15
    • 79952364000 scopus 로고    scopus 로고
    • Characterization of gliadin-specific Th17 cells from the mucosa of celiac disease patients
    • Fernandez S., Molina I.J., Romero P., Gonzalez R., Pena J., Sanchez F., et al. Characterization of gliadin-specific Th17 cells from the mucosa of celiac disease patients. Am J Gastroenterol 2011, 106:528-538.
    • (2011) Am J Gastroenterol , vol.106 , pp. 528-538
    • Fernandez, S.1    Molina, I.J.2    Romero, P.3    Gonzalez, R.4    Pena, J.5    Sanchez, F.6
  • 17
    • 77953192176 scopus 로고    scopus 로고
    • IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease-associated inflammation and lymphomagenesis
    • Malamut G., El Machhour R., Montcuquet N., Martin-Lanneree S., Dusanter-Fourt I., Verkarre V., et al. IL-15 triggers an antiapoptotic pathway in human intraepithelial lymphocytes that is a potential new target in celiac disease-associated inflammation and lymphomagenesis. J Clin Invest 2010, 120:2131-2143.
    • (2010) J Clin Invest , vol.120 , pp. 2131-2143
    • Malamut, G.1    El Machhour, R.2    Montcuquet, N.3    Martin-Lanneree, S.4    Dusanter-Fourt, I.5    Verkarre, V.6
  • 19
    • 33746547247 scopus 로고    scopus 로고
    • The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design
    • Waldmann T.A. The biology of interleukin-2 and interleukin-15: implications for cancer therapy and vaccine design. Nat Rev Immunol 2006, 6:595-601.
    • (2006) Nat Rev Immunol , vol.6 , pp. 595-601
    • Waldmann, T.A.1
  • 20
    • 79952389800 scopus 로고    scopus 로고
    • Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens
    • Depaolo R.W., Abadie V., Tang F., Fehlner-Peach H., Hall J.A., Wang W., et al. Co-adjuvant effects of retinoic acid and IL-15 induce inflammatory immunity to dietary antigens. Nature 2011, 471:220-225.
    • (2011) Nature , vol.471 , pp. 220-225
    • Depaolo, R.W.1    Abadie, V.2    Tang, F.3    Fehlner-Peach, H.4    Hall, J.A.5    Wang, W.6
  • 21
    • 70349463158 scopus 로고    scopus 로고
    • Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes
    • Yokoyama S., Watanabe N., Sato N., Perera P.Y., Filkoski L., Tanaka T., et al. Antibody-mediated blockade of IL-15 reverses the autoimmune intestinal damage in transgenic mice that overexpress IL-15 in enterocytes. Proc Natl Acad Sci U S A 2009, 106:15849-15854.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 15849-15854
    • Yokoyama, S.1    Watanabe, N.2    Sato, N.3    Perera, P.Y.4    Filkoski, L.5    Tanaka, T.6
  • 23
    • 0037072829 scopus 로고    scopus 로고
    • Gliadin T cell epitope selection by tissue transglutaminase in celiac disease. Role of enzyme specificity and pH influence on the transamidation versus deamidation process
    • Fleckenstein B., Molberg O., Qiao S.W., Schmid D.G., von der M.F., Elgstoen K., et al. Gliadin T cell epitope selection by tissue transglutaminase in celiac disease. Role of enzyme specificity and pH influence on the transamidation versus deamidation process. J Biol Chem 2002, 277:34109-34116.
    • (2002) J Biol Chem , vol.277 , pp. 34109-34116
    • Fleckenstein, B.1    Molberg, O.2    Qiao, S.W.3    Schmid, D.G.4    von der, M.F.5    Elgstoen, K.6
  • 24
    • 0037183929 scopus 로고    scopus 로고
    • Structural basis for gluten intolerance in celiac sprue
    • Shan L., Molberg O., Parrot I., Hausch F., Filiz F., Gray G.M., et al. Structural basis for gluten intolerance in celiac sprue. Science 2002, 297:2275-2279.
    • (2002) Science , vol.297 , pp. 2275-2279
    • Shan, L.1    Molberg, O.2    Parrot, I.3    Hausch, F.4    Filiz, F.5    Gray, G.M.6
  • 26
    • 0032740185 scopus 로고    scopus 로고
    • 31-43 Amino acid sequence of the alpha-gliadin induces anti-endomysial antibody production during in vitro challenge
    • Picarelli A., Di Tola M., Sabbatella L., Anania M.C., Di Cello T., Greco R., et al. 31-43 Amino acid sequence of the alpha-gliadin induces anti-endomysial antibody production during in vitro challenge. Scand J Gastroenterol 1999, 34:1099-1102.
    • (1999) Scand J Gastroenterol , vol.34 , pp. 1099-1102
    • Picarelli, A.1    Di Tola, M.2    Sabbatella, L.3    Anania, M.C.4    Di Cello, T.5    Greco, R.6
  • 27
    • 84864017435 scopus 로고    scopus 로고
    • Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules
    • Sollid L.M., Qiao S.W., Anderson R.P., Gianfrani C., Koning F. Nomenclature and listing of celiac disease relevant gluten T-cell epitopes restricted by HLA-DQ molecules. Immunogenetics 2012, 64:455-460.
    • (2012) Immunogenetics , vol.64 , pp. 455-460
    • Sollid, L.M.1    Qiao, S.W.2    Anderson, R.P.3    Gianfrani, C.4    Koning, F.5
  • 28
    • 40949132466 scopus 로고    scopus 로고
    • Analysis of the binding of gluten T-cell epitopes to various human leukocyte antigen class II molecules
    • Bergseng E., Sidney J., Sette A., Sollid L.M. Analysis of the binding of gluten T-cell epitopes to various human leukocyte antigen class II molecules. Hum Immunol 2008, 69:94-100.
    • (2008) Hum Immunol , vol.69 , pp. 94-100
    • Bergseng, E.1    Sidney, J.2    Sette, A.3    Sollid, L.M.4
  • 29
    • 80053079520 scopus 로고    scopus 로고
    • Posttranslational modification of gluten shapes TCR usage in celiac disease
    • Qiao S.W., Raki M., Gunnarsen K.S., Loset G.A., Lundin K.E., Sandlie I., et al. Posttranslational modification of gluten shapes TCR usage in celiac disease. J Immunol 2011, 187:3064-3071.
    • (2011) J Immunol , vol.187 , pp. 3064-3071
    • Qiao, S.W.1    Raki, M.2    Gunnarsen, K.S.3    Loset, G.A.4    Lundin, K.E.5    Sandlie, I.6
  • 30
    • 0142091358 scopus 로고    scopus 로고
    • The HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses
    • Vader W., Stepniak D., Kooy Y., Mearin L., Thompson A., van Rood J.J., et al. The HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses. Proc Natl Acad Sci U S A 2003, 100:12390-12395.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 12390-12395
    • Vader, W.1    Stepniak, D.2    Kooy, Y.3    Mearin, L.4    Thompson, A.5    van Rood, J.J.6
  • 31
    • 78149357599 scopus 로고    scopus 로고
    • Proteomic analyses lead to a better understanding of celiac disease: focus on epitope recognition and autoantibodies
    • De Re V., Simula M.P., Canzonieri V., Cannizzaro R. Proteomic analyses lead to a better understanding of celiac disease: focus on epitope recognition and autoantibodies. Dig Dis Sci 2010, 55:3041-3046.
    • (2010) Dig Dis Sci , vol.55 , pp. 3041-3046
    • De Re, V.1    Simula, M.P.2    Canzonieri, V.3    Cannizzaro, R.4
  • 32
    • 0027297974 scopus 로고
    • The activity of wheat gliadin peptides in in vitro assays for coeliac disease
    • Cornell H.J., Mothes T. The activity of wheat gliadin peptides in in vitro assays for coeliac disease. Biochim Biophys Acta 1993, 1181:169-173.
    • (1993) Biochim Biophys Acta , vol.1181 , pp. 169-173
    • Cornell, H.J.1    Mothes, T.2
  • 33
    • 33744495071 scopus 로고    scopus 로고
    • HCV-NS3 and IgG-Fc crossreactive IgM in patients with type II mixed cryoglobulinemia and B-cell clonal proliferations
    • De Re V., Sansonno D., Simula M.P., Caggiari L., Gasparotto D., Fabris M., et al. HCV-NS3 and IgG-Fc crossreactive IgM in patients with type II mixed cryoglobulinemia and B-cell clonal proliferations. Leukemia 2006, 20:1145-1154.
    • (2006) Leukemia , vol.20 , pp. 1145-1154
    • De Re, V.1    Sansonno, D.2    Simula, M.P.3    Caggiari, L.4    Gasparotto, D.5    Fabris, M.6
  • 34
    • 79551609573 scopus 로고    scopus 로고
    • Fast and efficient characterization of an anti-gliadin monoclonal antibody epitope related to celiac disease using resin-bound peptides
    • Petersen N.H., Hansen P.R., Houen G. Fast and efficient characterization of an anti-gliadin monoclonal antibody epitope related to celiac disease using resin-bound peptides. J Immunol Methods 2011, 365:174-182.
    • (2011) J Immunol Methods , vol.365 , pp. 174-182
    • Petersen, N.H.1    Hansen, P.R.2    Houen, G.3
  • 35
  • 36
    • 84855990625 scopus 로고    scopus 로고
    • A single conformational transglutaminase 2 epitope contributed by three domains is critical for celiac antibody binding and effects
    • Simon-Vecsei Z., Kiraly R., Bagossi P., Toth B., Dahlbom I., Caja S., et al. A single conformational transglutaminase 2 epitope contributed by three domains is critical for celiac antibody binding and effects. Proc Natl Acad Sci U S A 2012, 109:431-436.
    • (2012) Proc Natl Acad Sci U S A , vol.109 , pp. 431-436
    • Simon-Vecsei, Z.1    Kiraly, R.2    Bagossi, P.3    Toth, B.4    Dahlbom, I.5    Caja, S.6
  • 37
    • 79952387557 scopus 로고    scopus 로고
    • Dysfunctions of the Iga system: a common link between intestinal and renal diseases
    • Papista C., Berthelot L., Monteiro R.C. Dysfunctions of the Iga system: a common link between intestinal and renal diseases. Cell Mol Immunol 2011, 8:126-134.
    • (2011) Cell Mol Immunol , vol.8 , pp. 126-134
    • Papista, C.1    Berthelot, L.2    Monteiro, R.C.3
  • 38
    • 38749093329 scopus 로고    scopus 로고
    • Secretory IgA mediates retrotranscytosis of intact gliadin peptides via the transferrin receptor in celiac disease
    • Matysiak-Budnik T., Moura I.C., Arcos-Fajardo M., Lebreton C., Menard S., Candalh C., et al. Secretory IgA mediates retrotranscytosis of intact gliadin peptides via the transferrin receptor in celiac disease. J Exp Med 2008, 205:143-154.
    • (2008) J Exp Med , vol.205 , pp. 143-154
    • Matysiak-Budnik, T.1    Moura, I.C.2    Arcos-Fajardo, M.3    Lebreton, C.4    Menard, S.5    Candalh, C.6
  • 39
    • 0028024976 scopus 로고
    • Involvement of membrane-bound transglutaminase in the invagination of transferrin into rat reticulocyte plasma membrane
    • Katoh S., Midorikami J., Takasu S., Ohkubo Y. Involvement of membrane-bound transglutaminase in the invagination of transferrin into rat reticulocyte plasma membrane. Biol Pharm Bull 1994, 17:1003-1007.
    • (1994) Biol Pharm Bull , vol.17 , pp. 1003-1007
    • Katoh, S.1    Midorikami, J.2    Takasu, S.3    Ohkubo, Y.4
  • 40
    • 0026567830 scopus 로고
    • Association of subepithelial deposition of activated complement and immunoglobulin G and M response to gluten in celiac disease
    • Halstensen T.S., Hvatum M., Scott H., Fausa O., Brandtzaeg P. Association of subepithelial deposition of activated complement and immunoglobulin G and M response to gluten in celiac disease. Gastroenterology 1992, 102:751-759.
    • (1992) Gastroenterology , vol.102 , pp. 751-759
    • Halstensen, T.S.1    Hvatum, M.2    Scott, H.3    Fausa, O.4    Brandtzaeg, P.5
  • 41
    • 69249106881 scopus 로고    scopus 로고
    • Pathways and mechanisms of endocytic recycling
    • Grant B.D., Donaldson J.G. Pathways and mechanisms of endocytic recycling. Nat Rev Mol Cell Biol 2009, 10:597-608.
    • (2009) Nat Rev Mol Cell Biol , vol.10 , pp. 597-608
    • Grant, B.D.1    Donaldson, J.G.2
  • 42
    • 77957924395 scopus 로고    scopus 로고
    • Gliadin peptide P31-43 localises to endocytic vesicles and interferes with their maturation
    • Barone M.V., Nanayakkara M., Paolella G., Maglio M., Vitale V., Troiano R., et al. Gliadin peptide P31-43 localises to endocytic vesicles and interferes with their maturation. PLoS One 2010, 5:e12246.
    • (2010) PLoS One , vol.5
    • Barone, M.V.1    Nanayakkara, M.2    Paolella, G.3    Maglio, M.4    Vitale, V.5    Troiano, R.6
  • 43
    • 77649308933 scopus 로고    scopus 로고
    • Long-term and acute effects of gliadin on small intestine of patients on potentially pathogenic networks in celiac disease
    • Castellanos-Rubio A., Santin I., Martin-Pagola A., Irastorza I., Castano L., Vitoria J.C., et al. Long-term and acute effects of gliadin on small intestine of patients on potentially pathogenic networks in celiac disease. Autoimmunity 2010, 43:131-139.
    • (2010) Autoimmunity , vol.43 , pp. 131-139
    • Castellanos-Rubio, A.1    Santin, I.2    Martin-Pagola, A.3    Irastorza, I.4    Castano, L.5    Vitoria, J.C.6
  • 44
    • 77749318553 scopus 로고    scopus 로고
    • Lysosomal accumulation of gliadin p31-43 peptide induces oxidative stress and tissue transglutaminase-mediated PPARgamma downregulation in intestinal epithelial cells and coeliac mucosa
    • Luciani A., Villella V.R., Vasaturo A., Giardino I., Pettoello-Mantovani M., Guido S., et al. Lysosomal accumulation of gliadin p31-43 peptide induces oxidative stress and tissue transglutaminase-mediated PPARgamma downregulation in intestinal epithelial cells and coeliac mucosa. Gut 2010, 59:311-319.
    • (2010) Gut , vol.59 , pp. 311-319
    • Luciani, A.1    Villella, V.R.2    Vasaturo, A.3    Giardino, I.4    Pettoello-Mantovani, M.5    Guido, S.6
  • 45
    • 0036324712 scopus 로고    scopus 로고
    • Rapid endo-lysosomal escape of poly(DL-lactide-co-glycolide) nanoparticles: implications for drug and gene delivery
    • Panyam J., Zhou W.Z., Prabha S., Sahoo S.K., Labhasetwar V. Rapid endo-lysosomal escape of poly(DL-lactide-co-glycolide) nanoparticles: implications for drug and gene delivery. FASEB J 2002, 16:1217-1226.
    • (2002) FASEB J , vol.16 , pp. 1217-1226
    • Panyam, J.1    Zhou, W.Z.2    Prabha, S.3    Sahoo, S.K.4    Labhasetwar, V.5
  • 47
    • 84859915672 scopus 로고    scopus 로고
    • Early tissue transglutaminase-mediated response underlies K562(S)-cell gliadin-dependent agglutination
    • Silano M., Vincentini O., Luciani A., Felli C., Caserta S., Esposito S., et al. Early tissue transglutaminase-mediated response underlies K562(S)-cell gliadin-dependent agglutination. Pediatr Res 2012, 71:532-538.
    • (2012) Pediatr Res , vol.71 , pp. 532-538
    • Silano, M.1    Vincentini, O.2    Luciani, A.3    Felli, C.4    Caserta, S.5    Esposito, S.6
  • 48
    • 78649825827 scopus 로고    scopus 로고
    • Do gliadin and tissue transglutaminase mediate PPAR downregulation in intestinal cells of patients with coeliac disease?
    • De Re V., Simula M.P., Notarpietro A., Canzonieri V., Cannizzaro R., Toffoli G. Do gliadin and tissue transglutaminase mediate PPAR downregulation in intestinal cells of patients with coeliac disease?. Gut 2010, 59:1730-1731.
    • (2010) Gut , vol.59 , pp. 1730-1731
    • De Re, V.1    Simula, M.P.2    Notarpietro, A.3    Canzonieri, V.4    Cannizzaro, R.5    Toffoli, G.6
  • 49
    • 77951957075 scopus 로고    scopus 로고
    • PPAR signaling pathway and cancer-related proteins are involved in celiac disease-associated tissue damage
    • Simula M.P., Cannizzaro R., Canzonieri V., Pavan A., Maiero S., Toffoli G., et al. PPAR signaling pathway and cancer-related proteins are involved in celiac disease-associated tissue damage. Mol Med 2010, 16:199-209.
    • (2010) Mol Med , vol.16 , pp. 199-209
    • Simula, M.P.1    Cannizzaro, R.2    Canzonieri, V.3    Pavan, A.4    Maiero, S.5    Toffoli, G.6
  • 50
    • 84860440603 scopus 로고    scopus 로고
    • Chitosan oligosaccharide as potential therapy of inflammatory bowel disease: therapeutic efficacy and possible mechanisms of action
    • Yousef M., Pichyangkura R., Soodvilai S., Chatsudthipong V., Muanprasat C. Chitosan oligosaccharide as potential therapy of inflammatory bowel disease: therapeutic efficacy and possible mechanisms of action. Pharmacol Res 2012, 66:66-79.
    • (2012) Pharmacol Res , vol.66 , pp. 66-79
    • Yousef, M.1    Pichyangkura, R.2    Soodvilai, S.3    Chatsudthipong, V.4    Muanprasat, C.5
  • 51
    • 78751699186 scopus 로고    scopus 로고
    • Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer
    • Fasano A. Zonulin and its regulation of intestinal barrier function: the biological door to inflammation, autoimmunity, and cancer. Physiol Rev 2011, 91:151-175.
    • (2011) Physiol Rev , vol.91 , pp. 151-175
    • Fasano, A.1
  • 52
    • 84862983459 scopus 로고    scopus 로고
    • Zonulin, regulation of tight junctions, and autoimmune diseases
    • Fasano A. Zonulin, regulation of tight junctions, and autoimmune diseases. Ann N Y Acad Sci 2012, 1258:25-33.
    • (2012) Ann N Y Acad Sci , vol.1258 , pp. 25-33
    • Fasano, A.1
  • 53
    • 84858697696 scopus 로고    scopus 로고
    • Differences of small intestinal bacteria populations in adults and children with/without celiac disease: effect of age, gluten diet, and disease
    • Nistal E., Caminero A., Herr+ín A.R., Arias L., Vivas S., Ruiz De Morales J.M., et al. Differences of small intestinal bacteria populations in adults and children with/without celiac disease: effect of age, gluten diet, and disease. Inflamm Bowel Dis 2012, 18:649-656.
    • (2012) Inflamm Bowel Dis , vol.18 , pp. 649-656
    • Nistal, E.1    Caminero, A.2    Herr+ín, A.R.3    Arias, L.4    Vivas, S.5    Ruiz De Morales, J.M.6
  • 54
    • 84863393163 scopus 로고    scopus 로고
    • Proof of concept of microbiome-metabolome analysis and delayed gluten exposure on celiac disease autoimmunity in genetically at-risk infants
    • Sellitto M., Bai G., Serena G., Fricke W.F., Sturgeon C., Gajer P., et al. Proof of concept of microbiome-metabolome analysis and delayed gluten exposure on celiac disease autoimmunity in genetically at-risk infants. PLoS One 2012, 7.
    • (2012) PLoS One , vol.7
    • Sellitto, M.1    Bai, G.2    Serena, G.3    Fricke, W.F.4    Sturgeon, C.5    Gajer, P.6
  • 56
    • 80052399997 scopus 로고    scopus 로고
    • Lysozyme-rich mucus metaplasia in duodenal crypts supersedes Paneth cells in celiac disease
    • Rubio C.A. Lysozyme-rich mucus metaplasia in duodenal crypts supersedes Paneth cells in celiac disease. Virchows Arch 2011, 459:339-346.
    • (2011) Virchows Arch , vol.459 , pp. 339-346
    • Rubio, C.A.1
  • 57
    • 79960818162 scopus 로고    scopus 로고
    • Unraveling the ties between celiac disease and intestinal microbiota
    • Sanz Y., Pama G.D., Laparra M. Unraveling the ties between celiac disease and intestinal microbiota. Int Rev Immunol 2011, 30:207-218.
    • (2011) Int Rev Immunol , vol.30 , pp. 207-218
    • Sanz, Y.1    Pama, G.D.2    Laparra, M.3
  • 58
    • 80955180995 scopus 로고    scopus 로고
    • Intestinal microbiota in human health and disease: the impact of probiotics
    • Gerritsen J., Smidt H., Rijkers G.T., De Vos W.M. Intestinal microbiota in human health and disease: the impact of probiotics. Genes Nutr 2011, 6:209-240.
    • (2011) Genes Nutr , vol.6 , pp. 209-240
    • Gerritsen, J.1    Smidt, H.2    Rijkers, G.T.3    De Vos, W.M.4
  • 59
    • 79952527733 scopus 로고    scopus 로고
    • 'Gut health': a new objective in medicine?
    • Bischoff S.C. 'Gut health': a new objective in medicine?. BMC Med 2011, 9.
    • (2011) BMC Med , vol.9
    • Bischoff, S.C.1
  • 61
    • 79955425273 scopus 로고    scopus 로고
    • Are patients with potential celiac disease really potential? the answer of metabonomics
    • Bernini P., Bertini I., Calabro A., La Marca G., Lami G., Luchinat C., et al. Are patients with potential celiac disease really potential? the answer of metabonomics. J Proteome Res 2011, 10:714-721.
    • (2011) J Proteome Res , vol.10 , pp. 714-721
    • Bernini, P.1    Bertini, I.2    Calabro, A.3    La Marca, G.4    Lami, G.5    Luchinat, C.6
  • 63
    • 80355145697 scopus 로고    scopus 로고
    • Bio-physical characteristics of gastrointestinal mucosa of celiac patients: comparison with control subjects and effect of gluten free diet-
    • Bertolazzi S., Lanzarotto F., Zanini B., Ricci C., Villanacci V., Lanzini A. Bio-physical characteristics of gastrointestinal mucosa of celiac patients: comparison with control subjects and effect of gluten free diet- BMC Gastroenterol 2011, 11:119.
    • (2011) BMC Gastroenterol , vol.11 , pp. 119
    • Bertolazzi, S.1    Lanzarotto, F.2    Zanini, B.3    Ricci, C.4    Villanacci, V.5    Lanzini, A.6
  • 64
    • 70350509805 scopus 로고    scopus 로고
    • Intestinal mucosal barrier function in health and disease
    • Turner J.R. Intestinal mucosal barrier function in health and disease. Nat Rev Immunol 2009, 9:799-809.
    • (2009) Nat Rev Immunol , vol.9 , pp. 799-809
    • Turner, J.R.1
  • 65
    • 46049100586 scopus 로고    scopus 로고
    • Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3
    • Lammers K.M., Lu R., Brownley J., Lu B., Gerard C., Thomas K., et al. Gliadin induces an increase in intestinal permeability and zonulin release by binding to the chemokine receptor CXCR3. Gastroenterology 2008, 135:194-204.
    • (2008) Gastroenterology , vol.135 , pp. 194-204
    • Lammers, K.M.1    Lu, R.2    Brownley, J.3    Lu, B.4    Gerard, C.5    Thomas, K.6
  • 67
    • 32044441878 scopus 로고    scopus 로고
    • Gliadin stimulation of murine macrophage inflammatory gene expression and intestinal permeability are MyD88-dependent: role of the innate immune response in Celiac disease
    • Thomas K.E., Sapone A., Fasano A., Vogel S.N. Gliadin stimulation of murine macrophage inflammatory gene expression and intestinal permeability are MyD88-dependent: role of the innate immune response in Celiac disease. J Immunol 2006, 176:2512-2521.
    • (2006) J Immunol , vol.176 , pp. 2512-2521
    • Thomas, K.E.1    Sapone, A.2    Fasano, A.3    Vogel, S.N.4
  • 68
    • 79251607381 scopus 로고    scopus 로고
    • Identification of a novel immunomodulatory gliadin peptide that causes interleukin-8 release in a chemokine receptor CXCR3-dependent manner only in patients with coeliac disease
    • Lammers K.M., Khandelwal S., Chaudhry F., Kryszak D., Puppa E.L., Casolaro V., et al. Identification of a novel immunomodulatory gliadin peptide that causes interleukin-8 release in a chemokine receptor CXCR3-dependent manner only in patients with coeliac disease. Immunology 2011, 132:432-440.
    • (2011) Immunology , vol.132 , pp. 432-440
    • Lammers, K.M.1    Khandelwal, S.2    Chaudhry, F.3    Kryszak, D.4    Puppa, E.L.5    Casolaro, V.6
  • 69
    • 85028094075 scopus 로고    scopus 로고
    • Cell polarity-determining proteins Par-3 and PP-1 are involved in epithelial tight junction defects in coeliac disease
    • Schumann M., Günzel D., Buergel N., Richter J.F., Troeger H., May C., et al. Cell polarity-determining proteins Par-3 and PP-1 are involved in epithelial tight junction defects in coeliac disease. Gut 2012, 61:220-228.
    • (2012) Gut , vol.61 , pp. 220-228
    • Schumann, M.1    Günzel, D.2    Buergel, N.3    Richter, J.F.4    Troeger, H.5    May, C.6
  • 70
    • 79952218606 scopus 로고    scopus 로고
    • Gliadin-mediated proliferation and innate immune activation in celiac disease are due to alterations in vesicular trafficking
    • Barone M.V., Zanzi D., Maglio M., Nanayakkara M., Santagata S., Lania G., et al. Gliadin-mediated proliferation and innate immune activation in celiac disease are due to alterations in vesicular trafficking. PLoS One 2011, 6.
    • (2011) PLoS One , vol.6
    • Barone, M.V.1    Zanzi, D.2    Maglio, M.3    Nanayakkara, M.4    Santagata, S.5    Lania, G.6
  • 71
    • 82255192188 scopus 로고    scopus 로고
    • Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease
    • Trynka G., Hunt K.A., Bockett N.A., Romanos J., Mistry V., Szperl A., et al. Dense genotyping identifies and localizes multiple common and rare variant association signals in celiac disease. Nat Genet 2011, 43:1193-1201.
    • (2011) Nat Genet , vol.43 , pp. 1193-1201
    • Trynka, G.1    Hunt, K.A.2    Bockett, N.A.3    Romanos, J.4    Mistry, V.5    Szperl, A.6
  • 72
    • 77950243833 scopus 로고    scopus 로고
    • Multiple common variants for celiac disease influencing immune gene expression
    • Dubois P.C., Trynka G., Franke L., Hunt K.A., Romanos J., Curtotti A., et al. Multiple common variants for celiac disease influencing immune gene expression. Nat Genet 2010, 42:295-302.
    • (2010) Nat Genet , vol.42 , pp. 295-302
    • Dubois, P.C.1    Trynka, G.2    Franke, L.3    Hunt, K.A.4    Romanos, J.5    Curtotti, A.6
  • 73
    • 41349103493 scopus 로고    scopus 로고
    • Newly identified genetic risk variants for celiac disease related to the immune response
    • Hunt K.A., Zhernakova A., Turner G., Heap G.A., Franke L., Bruinenberg M., et al. Newly identified genetic risk variants for celiac disease related to the immune response. Nat Genet 2008, 40:395-402.
    • (2008) Nat Genet , vol.40 , pp. 395-402
    • Hunt, K.A.1    Zhernakova, A.2    Turner, G.3    Heap, G.A.4    Franke, L.5    Bruinenberg, M.6
  • 74
    • 58149091678 scopus 로고    scopus 로고
    • Shared and distinct genetic variants in type 1 diabetes and celiac disease
    • Smyth D.J., Plagnol V., Walker N.M., Cooper J.D., Downes K., Yang J.H., et al. Shared and distinct genetic variants in type 1 diabetes and celiac disease. N Engl J Med 2008, 359:2767-2777.
    • (2008) N Engl J Med , vol.359 , pp. 2767-2777
    • Smyth, D.J.1    Plagnol, V.2    Walker, N.M.3    Cooper, J.D.4    Downes, K.5    Yang, J.H.6
  • 75
    • 67649160603 scopus 로고    scopus 로고
    • Resistance to celiac disease in humanized HLA-DR3-DQ2-transgenic mice expressing specific anti-gliadin CD4+ T cells
    • de Kauwe A.L., Chen Z., Anderson R.P., Keech C.L., Price J.D., Wijburg O., et al. Resistance to celiac disease in humanized HLA-DR3-DQ2-transgenic mice expressing specific anti-gliadin CD4+ T cells. J Immunol 2009, 182:7440-7450.
    • (2009) J Immunol , vol.182 , pp. 7440-7450
    • de Kauwe, A.L.1    Chen, Z.2    Anderson, R.P.3    Keech, C.L.4    Price, J.D.5    Wijburg, O.6
  • 77
    • 80655149205 scopus 로고    scopus 로고
    • New IBD genetics: common pathways with other diseases
    • Lees C.W., Barrett J.C., Parkes M., Satsangi J. New IBD genetics: common pathways with other diseases. Gut 2011, 60:1739-1753.
    • (2011) Gut , vol.60 , pp. 1739-1753
    • Lees, C.W.1    Barrett, J.C.2    Parkes, M.3    Satsangi, J.4
  • 80
    • 84555203858 scopus 로고    scopus 로고
    • KIR/HLA combination associated with the risk of complications in celiac disease
    • Caggiari L., Toffoli G., De R.V., Orzes N., Spina M., De Zorzi M., et al. KIR/HLA combination associated with the risk of complications in celiac disease. Int J Biol Markers 2011, 26:221-228.
    • (2011) Int J Biol Markers , vol.26 , pp. 221-228
    • Caggiari, L.1    Toffoli, G.2    De, R.V.3    Orzes, N.4    Spina, M.5    De Zorzi, M.6
  • 82
    • 84874660788 scopus 로고    scopus 로고
    • Identification of a potential physiological precursor of aberrant cells in refractory coeliac disease type II
    • Schmitz F., Tjon J.M., Lai Y., Thompson A., Kooy-Winkelaar Y., Lemmers R.J., et al. Identification of a potential physiological precursor of aberrant cells in refractory coeliac disease type II. Gut 2012.
    • (2012) Gut
    • Schmitz, F.1    Tjon, J.M.2    Lai, Y.3    Thompson, A.4    Kooy-Winkelaar, Y.5    Lemmers, R.J.6
  • 83
    • 79952755799 scopus 로고    scopus 로고
    • Genome-virome interactions: examining the role of common viral infections in complex disease
    • Foxman E.F., Iwasaki A. Genome-virome interactions: examining the role of common viral infections in complex disease. Nat Rev Microbiol 2011, 9:254-264.
    • (2011) Nat Rev Microbiol , vol.9 , pp. 254-264
    • Foxman, E.F.1    Iwasaki, A.2
  • 84
    • 80054104616 scopus 로고    scopus 로고
    • KIR molecules: recent patents of interest for the diagnosis and treatment of several autoimmune diseases, chronic inflammation, and B-cell malignancies
    • De Re V., Caggiari L., De Zorzi M., Toffoli G. KIR molecules: recent patents of interest for the diagnosis and treatment of several autoimmune diseases, chronic inflammation, and B-cell malignancies. Recent Pat DNA Gene Seq 2011, 5:169-174.
    • (2011) Recent Pat DNA Gene Seq , vol.5 , pp. 169-174
    • De Re, V.1    Caggiari, L.2    De Zorzi, M.3    Toffoli, G.4
  • 86
    • 84856207904 scopus 로고    scopus 로고
    • The copolymer P(HEMA-co-SS) binds gluten and reduces immune response in gluten-sensitized mice and human tissues
    • Pinier M., Fuhrmann G., Galipeau H.J., Rivard N., Murray J.A., David C.S., et al. The copolymer P(HEMA-co-SS) binds gluten and reduces immune response in gluten-sensitized mice and human tissues. Gastroenterology 2012, 142:316-325.
    • (2012) Gastroenterology , vol.142 , pp. 316-325
    • Pinier, M.1    Fuhrmann, G.2    Galipeau, H.J.3    Rivard, N.4    Murray, J.A.5    David, C.S.6
  • 87
    • 70149093019 scopus 로고    scopus 로고
    • Induction of antigen-specific tolerance by oral administration of Lactococcus lactis delivered immunodominant DQ8-restricted gliadin peptide in sensitized nonobese diabetic Abo Dq8 transgenic mice
    • Huibregtse I.L., Marietta E.V., Rashtak S., Koning F., Rottiers P., David C.S., et al. Induction of antigen-specific tolerance by oral administration of Lactococcus lactis delivered immunodominant DQ8-restricted gliadin peptide in sensitized nonobese diabetic Abo Dq8 transgenic mice. J Immunol 2009, 183:2390-2396.
    • (2009) J Immunol , vol.183 , pp. 2390-2396
    • Huibregtse, I.L.1    Marietta, E.V.2    Rashtak, S.3    Koning, F.4    Rottiers, P.5    David, C.S.6
  • 89
    • 58249085436 scopus 로고    scopus 로고
    • Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse
    • Arrieta M.C., Madsen K., Doyle J., Meddings J. Reducing small intestinal permeability attenuates colitis in the IL10 gene-deficient mouse. Gut 2009, 58:41-48.
    • (2009) Gut , vol.58 , pp. 41-48
    • Arrieta, M.C.1    Madsen, K.2    Doyle, J.3    Meddings, J.4
  • 90
    • 84856777535 scopus 로고    scopus 로고
    • Bifidobacterium longum CECT 7347 modulates immune responses in a gliadin-induced enteropathy animal model
    • Laparra J.M., Olivares M., Gallina O., Sanz Y. Bifidobacterium longum CECT 7347 modulates immune responses in a gliadin-induced enteropathy animal model. PLoS One 2012, 7:e30744.
    • (2012) PLoS One , vol.7
    • Laparra, J.M.1    Olivares, M.2    Gallina, O.3    Sanz, Y.4


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