Lysozyme-rich mucus metaplasia in duodenal crypts supersedes Paneth cells in celiac disease

Virchows Archiv

Volumn 459, Issue 3, 2011, Pages 339-346

  Rubio, Carlos A ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Celiac disease; Crypts; Mucus metaplasia; Panneth cells

Indexed keywords

LYSOZYME;

ARTICLE; CELIAC DISEASE; CELL MIGRATION; CHILD; DUODENITIS; DUODENUM BIOPSY; FEMALE; GOBLET CELL; HUMAN; INTESTINE CELL; MAJOR CLINICAL STUDY; MALE; METAPLASIA; PANETH CELL; PRIORITY JOURNAL; STEM CELL;

CELIAC DISEASE; CHILD; CHILD, PRESCHOOL; CHRONIC DISEASE; DUODENITIS; DUODENUM; FEMALE; GOBLET CELLS; HUMANS; INTESTINAL MUCOSA; MALE; METAPLASIA; MICROVILLI; MURAMIDASE; PANETH CELLS; STAINING AND LABELING;

EID: 80052399997     PISSN: 09456317     EISSN: 14322307     Source Type: Journal    
DOI: 10.1007/s00428-011-1129-3     Document Type: Article

References (39)

1. Gramlich T, Petras R (2007) Small intestine/duodenum. In: Mills SE (ed) Histology for pathologists, 3rd edn. Lippincott Williams & Wilkins, Philadelphia, pp 613-616
2. XC He J Zhang WG Tong O Tawfik J Ross DH Scoville Q Tian X Zeng X He LM Wiedemann Y Mishina Li 2004 BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-beta-catenin signaling Nat Genet. 36 1117 1121 15378062 10.1038/ng1430 1:CAS:528:DC%2BD2cXnvFamtLY%3D (Pubitemid 41184475)
3. BP de Santa GR van den Brink DJ Roberts 2003 Development and differentiation of the intestinal epithelium Cell Mol Life Sci 60 1322 1332 10.1007/s00018-003-2289-3 Review (Pubitemid 36900516)
4. CA Rubio G Nesi 2003 A simple method to demonstrate normal and metaplastic Paneth cells in tissue sections In Vivo 17 67 71 12655793 1:STN:280:DC%2BD3s7ktFehug%3D%3D (Pubitemid 36382968)
5. T Ayabe T Ashida Y Kohgo T Kono 2004 The role of Paneth cells and their antimicrobial peptides in innate host defense Trends Microbiol 12 394 398 15276616 10.1016/j.tim.2004.06.007 1:CAS:528:DC%2BD2cXmtVahtb4%3D (Pubitemid 38987827)
6. M Sundbom DA Elphick YR Mahida RN Cunliffe T Midtvedt L Engstrand CA Rubio LG Axelsson 2007 Alteration in human defensin-5 expression following gastric bypass surgery J Clin Pathol 60 1029 1034 17412868 10.1136/jcp.2006. 041871 1:STN:280:DC%2BD2srgvFektQ%3D%3D (Pubitemid 47441937)
7. A Di Sabatino E Miceli W Dhaliwal P Biancheri R Salerno L Cantoro A Vanoli M De Vincenzi V Blanco Cdel TT MacDonald GR Corazza 2008 Distribution, proliferation, and function of Paneth cells in uncomplicated and complicated adult celiac disease Am J Clin Pathol 130 34 42 18550468 10.1309/ 5ADNAR4VN11TTKQ6
8. DH Dewar PJ Ciclitira 2005 Clinical features and diagnosis of celiac disease Gastroenterology. 128 Suppl 1 S19 24 15825122 10.1053/j.gastro.2005.02. 010 Review (Pubitemid 40460817)
9. L Högberg L Stenhammar 2009 Celiac disease: diagnosis criteria in young children Nat Rev Gastroenterol Hepatol. 6 447 448 19654599 10.1038/nrgastro.2009.111
10. A Ivarsson L Högberg L Stenhammar Swedish Childhood Coeliac Disease Working Group 2010 The Swedish Childhood Coeliac Disease Working Group after 20 years: history and future Acta Paediatr. 99 1429 1431 20394586 10.1111/j.1651-2227.2010.01832.x 1:STN:280:DC%2BC3cfpslChtg%3D%3D
11. A Myléus A Ivarsson C Webb L Danielsson O Hernell L Högberg E Karlsson C Lagerqvist F Norström A Rosén O Sandström L Stenhammar H Stenlund S Wall A Carlsson 2009 Celiac disease revealed in 3% of Swedish 12-year-olds born during an epidemic J Pediatr Gastroenterol Nutr 49 170 176 19516192 10.1097/MPG.0b013e31818c52cc
12. E Sánchez E Donat C Ribes-Koninckx M Calabuig Y Sanz 2010 Intestinal Bacteroides species associated with coeliac disease J Clin Pathol. 63 1105 1111 20972239 10.1136/jcp.2010.076950
13. S Schippa V Iebba M Barbato G Di Nardo V Totino MP Checchi C Longhi G Maiella S Cucchiara MP Conte 2010 A distinctive 'microbial signature' in celiac pediatric patients BMC Microbiol 10 175 179 20565734 10.1186/1471-2180-10-175
14. G Forsberg A Fahlgren P Hörstedt S Hammarström O Hernell ML Hammarström 2004 Presence of bacteria and innate immunity of intestinal epithelium in childhood celiac disease Am J Gastroenterol 99 894 904 15128357 10.1111/j.1572-0241.2004.04157.x (Pubitemid 39090220)
15. G Ou M Hedberg P Hörstedt V Baranov G Forsberg M Drobni O Sandström SN Wai I Johansson ML Hammarström O Hernell S Hammarström 2009 Proximal small intestinal microbiota and identification of rod-shaped bacteria associated with childhood celiac disease Am J Gastroenterol 104 3058 3067 19755974 10.1038/ajg.2009.524
16. A Fleming 1922 On a remarkable bacteriolytic element found in tissues and secretions Proc Roy Soc Sec B 93 306 317 10.1098/rspb.1922.0023 1:CAS:528:DyaB38XisV2gug%3D%3D
17. K Yoshimura A Toibana K Nakahama 1988 Human lysozyme: sequencing of a cDNA, and expression and secretion by Saccharomyces cerevisiae Biochem Biophys Res Commun 150 794 801 2829884 10.1016/0006-291X(88)90461-5 1:CAS:528: DyaL1cXktVWltr8%3D (Pubitemid 18039290)
18. C Peters U Kruse R Pollwein K Grzeschik Sippel 1989 The human lysozyme gene. Sequence organization and chromosomal localization Eur J Bioch 182 507 512 10.1111/j.1432-1033.1989.tb14857.x 1:CAS:528:DyaK3cXhtlentb0%3D
19. J Wehkamp H Chu B Shen RW Feathers RJ Kays SK Lee CL Bevins 2006 Paneth cell antimicrobial peptides: topographical distribution and quantification in human gastrointestinal tissues FEBS Lett. 580 5344 5350 16989824 10.1016/j.febslet.2006.08.083 1:CAS:528:DC%2BD28XpvFGntbk%3D (Pubitemid 44419568)
20. H Saito T Kasajima A Masuda Y Imai M Ishikawa 1988 Lysozyme localization in human gastric and duodenal epithelium. An immune-cytochemical study Cell Tissue Res 251 307 313 3345546 10.1007/BF00215838 1:CAS:528:DyaL1cXhtV2rurY%3D
21. CA Rubio R Befrits 2009 Increased lysozyme expression in gastric biopsies with intestinal metaplasia and pseudopyloric metaplasia Int J Clin Exp Med 2 248 253 19918317
22. Rubio CA, Lörinc (2011) Lysozyme is upregulated in Barrett's mucosa. Histopathology (in press)
23. Q Tang L Wang K Tao C Ge Y Jing Li JC Peng M Geng 2006 Expression of polymeric immunoglobulin receptor mRNA and protein in human Paneth cells: Paneth cells participate in acquired immunity Am J Gastroenterol 101 1625 1632 16863570 10.1111/j.1572-0241.2006.00605.x 1:CAS:528:DC%2BD28XotFKiur8%3D (Pubitemid 43980639)
24. Rubio CA (2011) Lysozyme expression in microscopic colitis. J Clin Pathol (in press)
25. CA Rubio 2003 Colorectal adenomas produce lysozyme Anticancer Res 23 5165 5171 14981984 1:CAS:528:DC%2BD2cXhvVWitLw%3D (Pubitemid 38182141)
26. E Helmerhorst M Zamakhchari D Schuppan F Oppenheim 2010 Discovery of a novel and rich source of gluten-degrading microbial enzymes in the oral cavity PLoS One 5 13264 13267 10.1371/journal.pone.0013264
27. M Hayat A Cairns MF Dixon S O'Mahony 2002 Quantitation of intraepithelial lymphocytes in human duodenum: what is normal? J Clin Pathol 55 393 394 11986350 10.1136/jcp.55.5.393 1:STN:280:DC%2BD383kslenug%3D%3D (Pubitemid 34494182)
28. DH Scoville T Sato XC He L Li 2008 Current view: intestinal stem cells and signaling Gastroenterology. 134 849 864 18325394 10.1053/j.gastro.2008.01. 079 1:CAS:528:DC%2BD1cXktlehtb0%3D Review (Pubitemid 351312767)
29. Rubio CA (2011) Putative stem cells in mucosas of the esophago-gastrointestinal tract. Chapter 10. In: Singh SR (ed) Stem cell, regenerative medicine and cancer. Nova Science Haupauge, NY, pp 281-310
30. C Kosinski DE Stange C Xu AS Chan C Ho ST Yuen RC Mifflin DW Powell H Clevers SY Leung X Chen 2010 Indian hedgehog regulates intestinal stem cell fate through epithelial-mesenchymal interactions during development Gastroenterology 139 893 903 20542037 10.1053/j.gastro.2010.06.014 1:CAS:528:DC%2BC3cXhtV2iurvE
31. N Barker M van de Wetering H Clevers 2008 The intestinal stem cell Genes Dev 22 1856 1864 18628392 10.1101/gad.1674008 1:CAS:528:DC%2BD1cXovFWlsLw%3D (Pubitemid 352008634)
32. T Nakamura K Tsuchiya T Watanabe 2007 Crosstalk between Wnt and Notch signaling in intestinal epithelial cell fate decision J Gastroenterol 42 705 710 17876539 10.1007/s00535-007-2087-z 1:CAS:528:DC%2BD2sXhtVGmtrzI (Pubitemid 47456757)
33. A Klaus W Birchmeier 2008 Wnt signalling and its impact on development and cancer Nat Rev Cancer 8 387 398 18432252 10.1038/nrc2389 1:CAS:528:DC%2BD1cXltVGlu7c%3D (Pubitemid 351589714)
34. NF Shroyer MA Helmrath VY Wang B Antalffy SJ Henning HY Zoghbi 2007 Intestine-specific ablation of Mouse atonal homolog 1 (Math1) reveals a role in cellular homeostasis Gastroenterology 132 2478 2488 17570220 10.1053/j.gastro.2007.03.047 1:CAS:528:DC%2BD2sXnvFOhu74%3D (Pubitemid 46890862)
35. KL VanDussen LC Samuelson 2010 Mouse atonal homolog 1 directs intestinal progenitors to secretory cell rather than absorptive cell fate Dev Biol 346 215 223 20691176 10.1016/j.ydbio.2010.07.026 1:CAS:528:DC%2BC3cXht1WmtL3J
36. F Varnat BB Heggeler P Grisel N Boucard I Corthésy-Theulaz W Wahli B Desvergne 2006 PPAR beta/delta regulates Paneth cell differentiation via controlling the hedgehog signaling pathway Gastroenterology 131 538 553 16890607 10.1053/j.gastro.2006.05.004 1:CAS:528:DC%2BD28XpsFyksbo%3D (Pubitemid 44160696)
37. Y Tanigawa R Yakura T Komiya 2007 The bHLH transcription factor Tcf12 (ME1) mRNA is abundantly expressed in Paneth cells of mouse intestine Gene Expr Patterns 7 709 713 17405739 10.1016/j.modgep.2007.02.003 1:CAS:528: DC%2BD2sXlvVOqt7o%3D (Pubitemid 46796773)
38. BA Babbin AJ Jesaitis AI Ivanov D Kelly M Laukoetter P Nava CA Parkos A Nusrat 2007 Formyl peptide receptor-1 activation enhances intestinal epithelial cell restitution through phosphatidylinositol 3-kinase-dependent activation of Rac1 and Cdc42 J Immunol 179 8112 8121 18056353 1:CAS:528:DC%2BD2sXhtlyitrbP
39. G Peignon A Durand W Cacheux O Ayrault B Terris P Laurent-Puig NF Shroyer I Van Seuningen T Honjo C Perret B Romagnolo 2011 Complex interplay between β-catenin signalling and Notch effectors in intestinal tumorigenesis Gut 60 166 176 21205878 10.1136/gut.2009.204719 1:CAS:528:DC%2BC3MXitlemurw%3D