메뉴 건너뛰기




Volumn 3, Issue 6, 2010, Pages 594-601

HLA-DQ2-restricted gluten-reactive T cells produce IL-21 but not IL-17 or IL-22

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GAMMA INTERFERON; GLIADIN; GLUTEN; HLA DQ2 ANTIGEN; HLA DQA1 ANTIGEN; HLA DQB1 ANTIGEN; INTERLEUKIN 17; INTERLEUKIN 21; INTERLEUKIN 22; MESSENGER RNA; TETRAMER;

EID: 77958169377     PISSN: 19330219     EISSN: None     Source Type: Journal    
DOI: 10.1038/mi.2010.36     Document Type: Article
Times cited : (125)

References (29)
  • 1
    • 33750025679 scopus 로고    scopus 로고
    • Coeliac disease: An update for pathologists
    • Dickson, B. C., Streutker, C. J. & Chetty, R. Coeliac disease: an update for pathologists. J. Clin. Pathol. 59, 1008-1016 (2006).
    • (2006) J. Clin. Pathol. , vol.59 , pp. 1008-1016
    • Dickson, B.C.1    Streutker, C.J.2    Chetty, R.3
  • 2
    • 0030877557 scopus 로고    scopus 로고
    • Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls
    • Molberg, Ø. et al. Gliadin specific, HLA DQ2-restricted T cells are commonly found in small intestinal biopsies from coeliac disease patients, but not from controls. Scand. J. Immunol. 46, 103-108 (1997).
    • (1997) Scand. J. Immunol. , vol.46 , pp. 103-108
    • Molberg, Ø.1
  • 3
    • 33746694192 scopus 로고    scopus 로고
    • HLA-DQ2 and-DQ8 signatures of gluten T cell epitopes in celiac disease
    • Tollefsen, S. et al. HLA-DQ2 and-DQ8 signatures of gluten T cell epitopes in celiac disease. J. Clin. Invest. 116, 2226-2236 (2006).
    • (2006) J. Clin. Invest. , vol.116 , pp. 2226-2236
    • Tollefsen, S.1
  • 4
    • 21244462254 scopus 로고    scopus 로고
    • Refining the rules of gliadin T cell epitope binding to the disease-associated DQ2 molecule in celiac disease: Importance of proline spacing and glutamine deamidation
    • Qiao, S. W. et al. Refining the rules of gliadin T cell epitope binding to the disease-associated DQ2 molecule in celiac disease: importance of proline spacing and glutamine deamidation. J. Immunol. 175, 254-261 (2005).
    • (2005) J. Immunol. , vol.175 , pp. 254-261
    • Qiao, S.W.1
  • 5
    • 0031779478 scopus 로고    scopus 로고
    • Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease
    • Molberg, Ø. et al. Tissue transglutaminase selectively modifies gliadin peptides that are recognized by gut-derived T cells in celiac disease. Nat. Med. 4, 713-717 (1998).
    • (1998) Nat. Med. , vol.4 , pp. 713-717
    • Molberg, Ø.1
  • 6
    • 0032528813 scopus 로고    scopus 로고
    • Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity
    • van de Waal, Y. et al. Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity. J. Immunol. 161, 1585-1588 (1998).
    • (1998) J. Immunol. , vol.161 , pp. 1585-1588
    • Van De Waal, Y.1
  • 7
    • 0037381091 scopus 로고    scopus 로고
    • *02 (DQ2) heterodimer: Results from the European Genetics Cluster on Celiac Disease
    • *02 (DQ2) heterodimer: results from the European Genetics Cluster on Celiac Disease. Hum. Immunol. 64, 469-477 (2003).
    • (2003) Hum. Immunol. , vol.64 , pp. 469-477
    • Karell, K.1
  • 8
  • 9
    • 77649220954 scopus 로고    scopus 로고
    • Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells
    • O'Shea, J. J. & Paul, W. E. Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells. Science 327, 1098-1102 (2010).
    • (2010) Science , vol.327 , pp. 1098-1102
    • O'Shea, J.J.1    Paul, W.E.2
  • 10
    • 0028828948 scopus 로고
    • Gluten specific, HLA-DQ restricted T cells from coeliac mucosa produce cytokines with Th1 or Th0 profile dominated by interferon gamma
    • Nilsen, E. M. et al. Gluten specific, HLA-DQ restricted T cells from coeliac mucosa produce cytokines with Th1 or Th0 profile dominated by interferon gamma. Gut 37, 766-776 (1995).
    • (1995) Gut , vol.37 , pp. 766-776
    • Nilsen, E.M.1
  • 11
    • 33746730381 scopus 로고    scopus 로고
    • Gliadin-specific type 1 regulatory T cells from the intestinal mucosa of treated celiac patients inhibit pathogenic T cells
    • Gianfrani, C. et al. Gliadin-specific type 1 regulatory T cells from the intestinal mucosa of treated celiac patients inhibit pathogenic T cells. J. Immunol. 177, 4178-4186 (2006).
    • (2006) J. Immunol. , vol.177 , pp. 4178-4186
    • Gianfrani, C.1
  • 12
    • 58149522346 scopus 로고    scopus 로고
    • TH17 (and TH1) signatures of intestinal biopsies of CD patients in response to gliadin
    • Castellanos-Rubio, A. et al. TH17 (and TH1) signatures of intestinal biopsies of CD patients in response to gliadin. Autoimmunity 42, 69-73 (2009).
    • (2009) Autoimmunity , vol.42 , pp. 69-73
    • Castellanos-Rubio, A.1
  • 13
    • 77949904749 scopus 로고    scopus 로고
    • Characterization of IL-17A-producing cells in celiac disease mucosa
    • Monteleone, I. et al. Characterization of IL-17A-producing cells in celiac disease mucosa. J. Immunol. 184, 2211-2218 (2010).
    • (2010) J. Immunol. , vol.184 , pp. 2211-2218
    • Monteleone, I.1
  • 14
    • 33847302982 scopus 로고    scopus 로고
    • Tetramer visualization of gut-homing gluten-specific T cells in the peripheral blood of celiac disease patients
    • Raki, M. et al. Tetramer visualization of gut-homing gluten-specific T cells in the peripheral blood of celiac disease patients. Proc. Natl. Acad. Sci. USA 104, 2831-2836 (2007).
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 2831-2836
    • Raki, M.1
  • 15
    • 23944522279 scopus 로고    scopus 로고
    • T cells in peripheral blood after gluten challenge in coeliac disease
    • Anderson, R. P. et al. T cells in peripheral blood after gluten challenge in coeliac disease. Gut 54, 1217-1223 (2005).
    • (2005) Gut , vol.54 , pp. 1217-1223
    • Anderson, R.P.1
  • 16
    • 66249133071 scopus 로고    scopus 로고
    • Isolation of mycobacterium avium subspecies paratuberculosis reactive CD4T cells from intestinal biopsies of Crohn's disease patients
    • Olsen, I. et al. Isolation of Mycobacterium avium subspecies paratuberculosis reactive CD4T cells from intestinal biopsies of Crohn's disease patients. PLoS ONE 4, e5641 (2009).
    • (2009) PLoS ONE , vol.4
    • Olsen, I.1
  • 19
    • 45149123617 scopus 로고    scopus 로고
    • Development and characterization of IL-21-producing CD4+ T cells
    • Suto, A. et al. Development and characterization of IL-21-producing CD4+ T cells. J. Exp. Med. 205, 1369-1379 (2008).
    • (2008) J. Exp. Med. , vol.205 , pp. 1369-1379
    • Suto, A.1
  • 20
    • 46349089381 scopus 로고    scopus 로고
    • Interleukin-21 contributes to the mucosal T helper cell type 1 response in celiac disease
    • Fina, D. et al. Interleukin-21 contributes to the mucosal T helper cell type 1 response in celiac disease. Gut 57, 887-892 (2007).
    • (2007) Gut , vol.57 , pp. 887-892
    • Fina, D.1
  • 22
    • 0037442137 scopus 로고    scopus 로고
    • IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger
    • Ferretti, S., Bonneau, O., Dubois, G. R., Jones, C. E. & Trifilieff, A. IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger. J. Immunol. 170, 2106-2112 (2003).
    • (2003) J. Immunol. , vol.170 , pp. 2106-2112
    • Ferretti, S.1    Bonneau, O.2    Dubois, G.R.3    Jones, C.E.4    Trifilieff, A.5
  • 23
    • 45749101727 scopus 로고    scopus 로고
    • Induction and effector functions of T (H) 17 cells
    • Bettelli, E., Korn, T., Oukka, M. & Kuchroo, V. K. Induction and effector functions of T (H) 17 cells. Nature 453, 1051-1057 (2008).
    • (2008) Nature , vol.453 , pp. 1051-1057
    • Bettelli, E.1    Korn, T.2    Oukka, M.3    Kuchroo, V.K.4
  • 24
    • 70349785595 scopus 로고    scopus 로고
    • Involvement of interleukin-15 and interleukin-21, two gamma-chain-related cytokines, in celiac disease
    • De Nitto, D., Monteleone, I., Franze, E., Pallone, F. & Monteleone, G. Involvement of interleukin-15 and interleukin-21, two gamma-chain-related cytokines, in celiac disease. World J. Gastroenterol. 15, 4609-4614 (2009).
    • (2009) World J. Gastroenterol. , vol.15 , pp. 4609-4614
    • De Nitto, D.1    Monteleone, I.2    Franze, E.3    Pallone, F.4    Monteleone, G.5
  • 25
    • 34347324029 scopus 로고    scopus 로고
    • A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21
    • van Heel, D. A. et al. A genome-wide association study for celiac disease identifies risk variants in the region harboring IL2 and IL21. Nat. Genet. 39, 827-829 (2007).
    • (2007) Nat. Genet. , vol.39 , pp. 827-829
    • Van Heel, D.A.1
  • 26
    • 33845671858 scopus 로고    scopus 로고
    • American gastroenterological association (AGA) Institute technical review on the diagnosis and management of celiac disease
    • Rostom, A., Murray, J. A. & Kagnoff, M. F. American Gastroenterological Association (AGA) Institute technical review on the diagnosis and management of celiac disease. Gastroenterology 131, 1981-2002 (2006).
    • (2006) Gastroenterology , vol.131 , pp. 1981-2002
    • Rostom, A.1    Murray, J.A.2    Kagnoff, M.F.3
  • 27
  • 28
    • 54049084929 scopus 로고    scopus 로고
    • Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DM
    • Fallang, L. E. et al. Complexes of two cohorts of CLIP peptides and HLA-DQ2 of the autoimmune DR3-DQ2 haplotype are poor substrates for HLA-DM. J. Immunol. 181, 5451-5461 (2008).
    • (2008) J. Immunol. , vol.181 , pp. 5451-5461
    • Fallang, L.E.1
  • 29
    • 0034066695 scopus 로고    scopus 로고
    • In vivo antigen challenge in celiac disease identifies a single transglutaminasemodified peptide as the dominant A-gliadin T-cell epitope
    • Anderson, R. P., Degano, P., Godkin, A. J., Jewell, D. P. & Hill, A. V. In vivo antigen challenge in celiac disease identifies a single transglutaminasemodified peptide as the dominant A-gliadin T-cell epitope. Nat. Med. 6, 337-342 (2000).
    • (2000) Nat. Med. , vol.6 , pp. 337-342
    • Anderson, R.P.1    Degano, P.2    Godkin, A.J.3    Jewell, D.P.4    Hill, A.V.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.