메뉴 건너뛰기




Volumn 4 DEC, Issue , 2013, Pages

The effects of obesity on skeletal muscle regeneration

Author keywords

Leptin; Lipids; Lipotoxicity; Muscle regeneration; Obesity; Satellite cells; Skeletal muscle; Type 2 diabetes

Indexed keywords

INSULIN; LEPTIN; MYOSTATIN; PROTEIN KINASE B; SOMATOMEDIN C;

EID: 84891698836     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2013.00371     Document Type: Review
Times cited : (187)

References (171)
  • 1
    • 0346729968 scopus 로고    scopus 로고
    • Ceramide content is increased in skeletal muscle from obese insulin-resistant humans
    • doi: 10.2337/diabetes.53.1.25
    • Adams, J. M. 2nd, Pratipanawatr, T., Berria, R., Wang, E., Defronzo, R. A., Sullards, M. C., et al. (2004). Ceramide content is increased in skeletal muscle from obese insulin-resistant humans. Diabetes 53, 25-31. doi: 10.2337/diabetes.53.1.25.
    • (2004) Diabetes , vol.53 , pp. 25-31
    • Adams II, J.M.1    Pratipanawatr, T.2    Berria, R.3    Wang, E.4    Defronzo, R.A.5    Sullards, M.C.6
  • 2
    • 78649839424 scopus 로고    scopus 로고
    • CCAAT/enhancer binding protein-delta expression is increased in fast skeletal muscle by food deprivation and regulates myostatin transcription in vitro
    • doi: 10.1152/ajpregu.00247.2010
    • Allen, D. L., Cleary, A. S., Hanson, A. M., Lindsay, S. F., and Reed, J. M. (2010). CCAAT/enhancer binding protein-delta expression is increased in fast skeletal muscle by food deprivation and regulates myostatin transcription in vitro. Am. J. Physiol. Regul. Integr. Comp. Physiol. 299, R1592-R1601. doi: 10.1152/ajpregu.00247.2010.
    • (2010) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.299
    • Allen, D.L.1    Cleary, A.S.2    Hanson, A.M.3    Lindsay, S.F.4    Reed, J.M.5
  • 3
    • 45549109223 scopus 로고    scopus 로고
    • Myostatin, activin receptor IIb, and follistatin-like-3 gene expression are altered in adipose tissue and skeletal muscle of obese mice
    • doi: 10.1152/ajpendo.00798.2007
    • Allen, D. L., Cleary, A. S., Speaker, K. J., Lindsay, S. F., Uyenishi, J., Reed, J. M., et al. (2008). Myostatin, activin receptor IIb, and follistatin-like-3 gene expression are altered in adipose tissue and skeletal muscle of obese mice. Am. J. Physiol. Endocrinol. Metab. 294, E918-E927. doi: 10.1152/ajpendo.00798.2007.
    • (2008) Am. J. Physiol. Endocrinol. Metab. , vol.294
    • Allen, D.L.1    Cleary, A.S.2    Speaker, K.J.3    Lindsay, S.F.4    Uyenishi, J.5    Reed, J.M.6
  • 4
    • 80052969358 scopus 로고    scopus 로고
    • Expression and function of myostatin in obesity, diabetes, and exercise adaptation
    • doi: 10.1249/MSS.0b013e3182178bb4
    • Allen, D. L., Hittel, D. S., and McPherron, A. C. (2011). Expression and function of myostatin in obesity, diabetes, and exercise adaptation. Med. Sci. Sports Exerc. 43, 1828-1835. doi: 10.1249/MSS.0b013e3182178bb4.
    • (2011) Med. Sci. Sports Exerc. , vol.43 , pp. 1828-1835
    • Allen, D.L.1    Hittel, D.S.2    McPherron, A.C.3
  • 5
    • 78651353542 scopus 로고    scopus 로고
    • Posttranscriptional mechanisms involving microRNA-27a and b contribute to fast-specific and glucocorticoid-mediated myostatin expression in skeletal muscle
    • doi: 10.1152/ajpcell.00142.2010
    • Allen, D. L., and Loh, A. S. (2011). Posttranscriptional mechanisms involving microRNA-27a and b contribute to fast-specific and glucocorticoid-mediated myostatin expression in skeletal muscle. Am. J. Physiol. Cell Physiol. 300, C124-C137. doi: 10.1152/ajpcell.00142.2010.
    • (2011) Am. J. Physiol. Cell Physiol. , vol.300
    • Allen, D.L.1    Loh, A.S.2
  • 6
    • 33846332013 scopus 로고    scopus 로고
    • Regulation of myostatin expression and myoblast differentiation by FoxO and SMAD transcription factors
    • doi: 10.1152/ajpcell.00542.2005
    • Allen, D. L., and Unterman, T. G. (2007). Regulation of myostatin expression and myoblast differentiation by FoxO and SMAD transcription factors. Am. J. Physiol. Cell Physiol. 292, C188-C199. doi: 10.1152/ajpcell.00542.2005.
    • (2007) Am. J. Physiol. Cell Physiol. , vol.292
    • Allen, D.L.1    Unterman, T.G.2
  • 7
    • 68549139946 scopus 로고    scopus 로고
    • Clinical review: the pathogenetic role of cortisol in the metabolic syndrome: a hypothesis
    • doi: 10.1210/jc.2009-0370
    • Anagnostis, P., Athyros, V. G., Tziomalos, K., Karagiannis, A., and Mikhailidis, D. P. (2009). Clinical review: the pathogenetic role of cortisol in the metabolic syndrome: a hypothesis. J. Clin. Endocrinol. Metab. 94, 2692-2701. doi: 10.1210/jc.2009-0370.
    • (2009) J. Clin. Endocrinol. Metab. , vol.94 , pp. 2692-2701
    • Anagnostis, P.1    Athyros, V.G.2    Tziomalos, K.3    Karagiannis, A.4    Mikhailidis, D.P.5
  • 8
    • 34248997759 scopus 로고    scopus 로고
    • Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis
    • doi: 10.1084/jem.20070075
    • Arnold, L., Henry, A., Poron, F., Baba-Amer, Y., Van Rooijen, N., Plonquet, A., et al. (2007). Inflammatory monocytes recruited after skeletal muscle injury switch into antiinflammatory macrophages to support myogenesis. J. Exp. Med. 204, 1057-1069. doi: 10.1084/jem.20070075.
    • (2007) J. Exp. Med. , vol.204 , pp. 1057-1069
    • Arnold, L.1    Henry, A.2    Poron, F.3    Baba-Amer, Y.4    Van Rooijen, N.5    Plonquet, A.6
  • 9
    • 84881516907 scopus 로고    scopus 로고
    • Absence of functional leptin receptor isoforms in the POUND (Lepr(db/lb)) mouse is associated with muscle atrophy and altered myoblast proliferation and differentiation
    • doi: 10.1371/annotation/3a7d6e24-137c-4603-93ca-879bec7fab80
    • Arounleut, P., Bowser, M., Upadhyay, S., Shi, X. M., Fulzele, S., Johnson, M. H., et al. (2013). Absence of functional leptin receptor isoforms in the POUND (Lepr(db/lb)) mouse is associated with muscle atrophy and altered myoblast proliferation and differentiation. PLoS ONE 8:e72330. doi: 10.1371/annotation/3a7d6e24-137c-4603-93ca-879bec7fab80.
    • (2013) PLoS ONE , vol.8
    • Arounleut, P.1    Bowser, M.2    Upadhyay, S.3    Shi, X.M.4    Fulzele, S.5    Johnson, M.H.6
  • 10
    • 7044235846 scopus 로고    scopus 로고
    • Vascular endothelial growth factor stimulates skeletal muscle regeneration in vivo
    • doi: 10.1016/j.ymthe.2004.08.007
    • Arsic, N., Zacchigna, S., Zentilin, L., Ramirez-Correa, G., Pattarini, L., Salvi, A., et al. (2004). Vascular endothelial growth factor stimulates skeletal muscle regeneration in vivo. Mol. Ther. 10, 844-854. doi: 10.1016/j.ymthe.2004.08.007.
    • (2004) Mol. Ther. , vol.10 , pp. 844-854
    • Arsic, N.1    Zacchigna, S.2    Zentilin, L.3    Ramirez-Correa, G.4    Pattarini, L.5    Salvi, A.6
  • 11
    • 80555124939 scopus 로고    scopus 로고
    • Ceramides as modulators of cellular and whole-body metabolism
    • doi: 10.1172/JCI57144
    • Bikman, B. T., and Summers, S. A. (2011). Ceramides as modulators of cellular and whole-body metabolism. J. Clin. Invest. 121, 4222-4230. doi: 10.1172/JCI57144.
    • (2011) J. Clin. Invest. , vol.121 , pp. 4222-4230
    • Bikman, B.T.1    Summers, S.A.2
  • 12
    • 0030898288 scopus 로고    scopus 로고
    • Reinnervation and regeneration of denervated rat soleus muscles
    • doi: 10.1002/(SICI)1097-4598(199706)20:6<744::AID-MUS13>3.0.CO;2-U
    • Billington, L. (1997). Reinnervation and regeneration of denervated rat soleus muscles. Muscle Nerve 20, 744-746. doi: 10.1002/(SICI)1097-4598(199706)20:6<744::AID-MUS13>3.0.CO;2-U.
    • (1997) Muscle Nerve , vol.20 , pp. 744-746
    • Billington, L.1
  • 13
    • 84859951558 scopus 로고    scopus 로고
    • Rapid determination of myosin heavy chain expression in rat, mouse, and human skeletal muscle using multicolor immunofluorescence analysis
    • doi: 10.1371/journal.pone.0035273
    • Bloemberg, D., and Quadrilatero, J. (2012). Rapid determination of myosin heavy chain expression in rat, mouse, and human skeletal muscle using multicolor immunofluorescence analysis. PLoS ONE 7:e35273. doi: 10.1371/journal.pone.0035273.
    • (2012) PLoS ONE , vol.7
    • Bloemberg, D.1    Quadrilatero, J.2
  • 14
    • 61949462399 scopus 로고    scopus 로고
    • Skeletal muscle growth in young rats is inhibited by chronic exposure to IL-6 but preserved by concurrent voluntary endurance exercise
    • doi: 10.1152/japplphysiol.90831.2008
    • Bodell, P. W., Kodesh, E., Haddad, F., Zaldivar, F. P., Cooper, D. M., and Adams, G. R. (2009). Skeletal muscle growth in young rats is inhibited by chronic exposure to IL-6 but preserved by concurrent voluntary endurance exercise. J. Appl. Physiol. 106, 443-453. doi: 10.1152/japplphysiol.90831.2008.
    • (2009) J. Appl. Physiol. , vol.106 , pp. 443-453
    • Bodell, P.W.1    Kodesh, E.2    Haddad, F.3    Zaldivar, F.P.4    Cooper, D.M.5    Adams, G.R.6
  • 15
    • 8844255630 scopus 로고    scopus 로고
    • Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction
    • doi: 10.1046/j.1365-2362.32.s3.3.x
    • Boden, G., and Shulman, G. I. (2002). Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and beta-cell dysfunction. Eur. J. Clin. Invest. 32(Suppl. 3), 14-23. doi: 10.1046/j.1365-2362.32.s3.3.x.
    • (2002) Eur. J. Clin. Invest. , vol.32 , Issue.SUPPL. 3 , pp. 14-23
    • Boden, G.1    Shulman, G.I.2
  • 16
    • 33750735034 scopus 로고    scopus 로고
    • mTOR signaling and the molecular adaptation to resistance exercise
    • doi: 10.1249/01.mss.0000233797.24035.35
    • Bodine, S. C. (2006). mTOR signaling and the molecular adaptation to resistance exercise. Med. Sci. Sports Exerc. 38, 1950-1957. doi: 10.1249/01.mss.0000233797.24035.35.
    • (2006) Med. Sci. Sports Exerc. , vol.38 , pp. 1950-1957
    • Bodine, S.C.1
  • 17
    • 0035736260 scopus 로고    scopus 로고
    • Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo
    • doi: 10.1038/ncb1101-1014
    • Bodine, S. C., Stitt, T. N., Gonzalez, M., Kline, W. O., Stover, G. L., Bauerlein, R., et al. (2001). Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo. Nat. Cell Biol. 3, 1014-1019. doi: 10.1038/ncb1101-1014.
    • (2001) Nat. Cell Biol. , vol.3 , pp. 1014-1019
    • Bodine, S.C.1    Stitt, T.N.2    Gonzalez, M.3    Kline, W.O.4    Stover, G.L.5    Bauerlein, R.6
  • 18
    • 33751375983 scopus 로고    scopus 로고
    • Role of proton MR for the study of muscle lipid metabolism
    • doi: 10.1002/nbm.1096
    • Boesch, C., Machann, J., Vermathen, P., and Schick, F. (2006). Role of proton MR for the study of muscle lipid metabolism. NMR Biomed. 19, 968-988. doi: 10.1002/nbm.1096.
    • (2006) NMR Biomed. , vol.19 , pp. 968-988
    • Boesch, C.1    Machann, J.2    Vermathen, P.3    Schick, F.4
  • 19
    • 4544355465 scopus 로고    scopus 로고
    • Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of skeletal muscle fatty acid transport and increased sarcolemmal FAT/CD36
    • doi: 10.1096/fj.03-1065fje
    • Bonen, A., Parolin, M. L., Steinberg, G. R., Calles-Escandon, J., Tandon, N. N., Glatz, J. F., et al. (2004). Triacylglycerol accumulation in human obesity and type 2 diabetes is associated with increased rates of skeletal muscle fatty acid transport and increased sarcolemmal FAT/CD36. FASEB J. 18, 1144-1146. doi: 10.1096/fj.03-1065fje.
    • (2004) FASEB J. , vol.18 , pp. 1144-1146
    • Bonen, A.1    Parolin, M.L.2    Steinberg, G.R.3    Calles-Escandon, J.4    Tandon, N.N.5    Glatz, J.F.6
  • 20
    • 38849199866 scopus 로고    scopus 로고
    • Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice
    • doi: 10.1172/JCI32601
    • Bonnard, C., Durand, A., Peyrol, S., Chanseaume, E., Chauvin, M. A., Morio, B., et al. (2008). Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice. J. Clin. Invest. 118, 789-800. doi: 10.1172/JCI32601.
    • (2008) J. Clin. Invest. , vol.118 , pp. 789-800
    • Bonnard, C.1    Durand, A.2    Peyrol, S.3    Chanseaume, E.4    Chauvin, M.A.5    Morio, B.6
  • 21
    • 83455229494 scopus 로고    scopus 로고
    • Re-evaluating lipotoxic triggers in skeletal muscle: relating intramyocellular lipid metabolism to insulin sensitivity
    • doi: 10.1016/j.plipres.2011.11.003
    • Bosma, M., Kersten, S., Hesselink, M. K., and Schrauwen, P. (2012). Re-evaluating lipotoxic triggers in skeletal muscle: relating intramyocellular lipid metabolism to insulin sensitivity. Prog. Lipid Res. 51, 36-49. doi: 10.1016/j.plipres.2011.11.003.
    • (2012) Prog. Lipid Res. , vol.51 , pp. 36-49
    • Bosma, M.1    Kersten, S.2    Hesselink, M.K.3    Schrauwen, P.4
  • 22
    • 2942555110 scopus 로고    scopus 로고
    • IL-1beta impairs insulin-like growth factor i-induced differentiation and downstream activation signals of the insulin-like growth factor i receptor in myoblasts
    • doi: 10.1210/en.2003-0087
    • Broussard, S. R., McCusker, R. H., Novakofski, J. E., Strle, K., Shen, W. H., Johnson, R. W., et al. (2004). IL-1beta impairs insulin-like growth factor i-induced differentiation and downstream activation signals of the insulin-like growth factor i receptor in myoblasts. J. Immunol. 172, 7713-7720. doi: 10.1210/en.2003-0087.
    • (2004) J. Immunol. , vol.172 , pp. 7713-7720
    • Broussard, S.R.1    McCusker, R.H.2    Novakofski, J.E.3    Strle, K.4    Shen, W.H.5    Johnson, R.W.6
  • 23
    • 0038721699 scopus 로고    scopus 로고
    • Cytokine-hormone interactions: tumor necrosis factor alpha impairs biologic activity and downstream activation signals of the insulin-like growth factor I receptor in myoblasts
    • doi: 10.1210/en.2003-0087
    • Broussard, S. R., McCusker, R. H., Novakofski, J. E., Strle, K., Shen, W. H., Johnson, R. W., et al. (2003). Cytokine-hormone interactions: tumor necrosis factor alpha impairs biologic activity and downstream activation signals of the insulin-like growth factor I receptor in myoblasts. Endocrinology 144, 2988-2996. doi: 10.1210/en.2003-0087.
    • (2003) Endocrinology , vol.144 , pp. 2988-2996
    • Broussard, S.R.1    McCusker, R.H.2    Novakofski, J.E.3    Strle, K.4    Shen, W.H.5    Johnson, R.W.6
  • 24
    • 62749140758 scopus 로고    scopus 로고
    • Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance
    • doi: 10.2337/db08-1078
    • Bruce, C. R., Hoy, A. J., Turner, N., Watt, M. J., Allen, T. L., Carpenter, K., et al. (2009). Overexpression of carnitine palmitoyltransferase-1 in skeletal muscle is sufficient to enhance fatty acid oxidation and improve high-fat diet-induced insulin resistance. Diabetes 58, 550-558. doi: 10.2337/db08-1078.
    • (2009) Diabetes , vol.58 , pp. 550-558
    • Bruce, C.R.1    Hoy, A.J.2    Turner, N.3    Watt, M.J.4    Allen, T.L.5    Carpenter, K.6
  • 25
    • 77956996905 scopus 로고    scopus 로고
    • Myonuclei acquired by overload exercise precede hypertrophy and are not lost on detraining
    • doi: 10.1073/pnas.0913935107
    • Bruusgaard, J. C., Johansen, I. B., Egner, I. M., Rana, Z. A., and Gundersen, K. (2010). Myonuclei acquired by overload exercise precede hypertrophy and are not lost on detraining. Proc. Natl. Acad. Sci. U.S.A. 107, 15111-15116. doi: 10.1073/pnas.0913935107.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 15111-15116
    • Bruusgaard, J.C.1    Johansen, I.B.2    Egner, I.M.3    Rana, Z.A.4    Gundersen, K.5
  • 27
    • 0035487315 scopus 로고    scopus 로고
    • A role for protein phosphatase 2A-like activity, but not atypical protein kinase Czeta, in the inhibition of protein kinase B/Akt and glycogen synthesis by palmitate
    • doi: 10.2337/diabetes.50.10.2210
    • Cazzolli, R., Carpenter, L., Biden, T. J., and Schmitz-Peiffer, C. (2001). A role for protein phosphatase 2A-like activity, but not atypical protein kinase Czeta, in the inhibition of protein kinase B/Akt and glycogen synthesis by palmitate. Diabetes 50, 2210-2218. doi: 10.2337/diabetes.50.10.2210.
    • (2001) Diabetes , vol.50 , pp. 2210-2218
    • Cazzolli, R.1    Carpenter, L.2    Biden, T.J.3    Schmitz-Peiffer, C.4
  • 28
    • 84860614281 scopus 로고    scopus 로고
    • Short-term calorie restriction enhances skeletal muscle stem cell function
    • doi: 10.1016/j.stem.2012.04.002
    • Cerletti, M., Jang, Y. C., Finley, L. W., Haigis, M. C., and Wagers, A. J. (2012). Short-term calorie restriction enhances skeletal muscle stem cell function. Cell Stem Cell 10, 515-519. doi: 10.1016/j.stem.2012.04.002.
    • (2012) Cell Stem Cell , vol.10 , pp. 515-519
    • Cerletti, M.1    Jang, Y.C.2    Finley, L.W.3    Haigis, M.C.4    Wagers, A.J.5
  • 29
    • 0347989458 scopus 로고    scopus 로고
    • Cellular and molecular regulation of muscle regeneration
    • doi: 10.1152/physrev.00019.2003
    • Charge, S. B., and Rudnicki, M. A. (2004). Cellular and molecular regulation of muscle regeneration. Physiol Rev. 84, 209-238. doi: 10.1152/physrev.00019.2003.
    • (2004) Physiol Rev. , vol.84 , pp. 209-238
    • Charge, S.B.1    Rudnicki, M.A.2
  • 30
    • 0038532298 scopus 로고    scopus 로고
    • A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids
    • doi: 10.1074/jbc.M212307200
    • Chavez, J. A., Knotts, T. A., Wang, L. P., Li, G., Dobrowsky, R. T., Florant, G. L., et al. (2003). A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids. J. Biol. Chem. 278, 10297-10303. doi: 10.1074/jbc.M212307200.
    • (2003) J. Biol. Chem. , vol.278 , pp. 10297-10303
    • Chavez, J.A.1    Knotts, T.A.2    Wang, L.P.3    Li, G.4    Dobrowsky, R.T.5    Florant, G.L.6
  • 31
    • 84864293537 scopus 로고    scopus 로고
    • Role of intramyocelluar lipids in human health
    • doi: 10.1016/j.tem.2012.05.009
    • Coen, P. M., and Goodpaster, B. H. (2012). Role of intramyocelluar lipids in human health. Trends Endocrinol. Metab. 23, 391-398. doi: 10.1016/j.tem.2012.05.009.
    • (2012) Trends Endocrinol. Metab. , vol.23 , pp. 391-398
    • Coen, P.M.1    Goodpaster, B.H.2
  • 32
    • 0024289805 scopus 로고
    • Regeneration after cardiotoxin injury of innervated and denervated slow and fast muscles of mammals. Myosin isoform analysis
    • doi: 10.1111/j.1432-1033.1988.tb14068.x
    • d'Albis, A., Couteaux, R., Janmot, C., Roulet, A., and Mira, J. C. (1988). Regeneration after cardiotoxin injury of innervated and denervated slow and fast muscles of mammals. Myosin isoform analysis. Eur. J. Biochem. 174, 103-110. doi: 10.1111/j.1432-1033.1988.tb14068.x.
    • (1988) Eur. J. Biochem. , vol.174 , pp. 103-110
    • d'Albis, A.1    Couteaux, R.2    Janmot, C.3    Roulet, A.4    Mira, J.C.5
  • 33
    • 84863863364 scopus 로고    scopus 로고
    • TNF-alpha-and tumor-induced skeletal muscle atrophy involves sphingolipid metabolism
    • doi: 10.1186/2044-5040-2-2
    • De Larichaudy, J., Zufferli, A., Serra, F., Isidori, A. M., Naro, F., Dessalle, K., et al. (2012). TNF-alpha-and tumor-induced skeletal muscle atrophy involves sphingolipid metabolism. Skelet. Muscle 2, 2. doi: 10.1186/2044-5040-2-2.
    • (2012) Skelet. Muscle , vol.2 , pp. 2
    • De Larichaudy, J.1    Zufferli, A.2    Serra, F.3    Isidori, A.M.4    Naro, F.5    Dessalle, K.6
  • 34
    • 70349850473 scopus 로고    scopus 로고
    • Effect of VEGF on the regenerative capacity of muscle stem cells in dystrophic skeletal muscle
    • doi: 10.1038/mt.2009.136
    • Deasy, B. M., Feduska, J. M., Payne, T. R., Li, Y., Ambrosio, F., and Huard, J. (2009). Effect of VEGF on the regenerative capacity of muscle stem cells in dystrophic skeletal muscle. Mol. Ther. 17, 1788-1798. doi: 10.1038/mt.2009.136.
    • (2009) Mol. Ther. , vol.17 , pp. 1788-1798
    • Deasy, B.M.1    Feduska, J.M.2    Payne, T.R.3    Li, Y.4    Ambrosio, F.5    Huard, J.6
  • 35
    • 84866551217 scopus 로고    scopus 로고
    • IL-10 triggers changes in macrophage phenotype that promote muscle growth and regeneration
    • doi: 10.4049/jimmunol.1103180
    • Deng, B., Wehling-Henricks, M., Villalta, S. A., Wang, Y., and Tidball, J. G. (2012). IL-10 triggers changes in macrophage phenotype that promote muscle growth and regeneration. J. Immunol. 189, 3669-3680. doi: 10.4049/jimmunol.1103180.
    • (2012) J. Immunol. , vol.189 , pp. 3669-3680
    • Deng, B.1    Wehling-Henricks, M.2    Villalta, S.A.3    Wang, Y.4    Tidball, J.G.5
  • 36
    • 66649088033 scopus 로고    scopus 로고
    • In vivo assessment of mouse hindleg intramyocellular lipids by 1H-MR spectroscopy
    • doi: 10.1016/j.acra.2008.12.007
    • Fissoune, R., Janier, M., Briguet, A., and Hiba, B. (2009). In vivo assessment of mouse hindleg intramyocellular lipids by 1H-MR spectroscopy. Acad. Radiol. 16, 890-896. doi: 10.1016/j.acra.2008.12.007.
    • (2009) Acad. Radiol. , vol.16 , pp. 890-896
    • Fissoune, R.1    Janier, M.2    Briguet, A.3    Hiba, B.4
  • 37
    • 0030924558 scopus 로고    scopus 로고
    • Transient exposure of human myoblasts to tumor necrosis factor-alpha inhibits serum and insulin-like growth factor-I stimulated protein synthesis
    • doi: 10.1210/en.138.10.4153
    • Frost, R. A., Lang, C. H., and Gelato, M. C. (1997). Transient exposure of human myoblasts to tumor necrosis factor-alpha inhibits serum and insulin-like growth factor-I stimulated protein synthesis. Endocrinology 138, 4153-4159. doi: 10.1210/en.138.10.4153.
    • (1997) Endocrinology , vol.138 , pp. 4153-4159
    • Frost, R.A.1    Lang, C.H.2    Gelato, M.C.3
  • 38
    • 48749110651 scopus 로고    scopus 로고
    • Lipid droplets: a classic organelle with new outfits
    • doi: 10.1007/s00418-008-0449-0
    • Fujimoto, T., Ohsaki, Y., Cheng, J., Suzuki, M., and Shinohara, Y. (2008). Lipid droplets: a classic organelle with new outfits. Histochem. Cell. Biol. 130, 263-279. doi: 10.1007/s00418-008-0449-0.
    • (2008) Histochem. Cell. Biol. , vol.130 , pp. 263-279
    • Fujimoto, T.1    Ohsaki, Y.2    Cheng, J.3    Suzuki, M.4    Shinohara, Y.5
  • 39
    • 43049121395 scopus 로고    scopus 로고
    • Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt
    • doi: 10.1016/j.devcel.2008.02.004
    • Fulco, M., Cen, Y., Zhao, P., Hoffman, E. P., McBurney, M. W., Sauve, A. A., et al. (2008). Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Dev. Cell. 14, 661-673. doi: 10.1016/j.devcel.2008.02.004.
    • (2008) Dev. Cell. , vol.14 , pp. 661-673
    • Fulco, M.1    Cen, Y.2    Zhao, P.3    Hoffman, E.P.4    McBurney, M.W.5    Sauve, A.A.6
  • 40
    • 0043244921 scopus 로고    scopus 로고
    • Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state
    • doi: 10.1016/S1097-2765(03)00226-0
    • Fulco, M., Schiltz, R. L., Iezzi, S., King, M. T., Zhao, P., Kashiwaya, Y., et al. (2003). Sir2 regulates skeletal muscle differentiation as a potential sensor of the redox state. Mol. Cell. 12, 51-62. doi: 10.1016/S1097-2765(03)00226-0.
    • (2003) Mol. Cell. , vol.12 , pp. 51-62
    • Fulco, M.1    Schiltz, R.L.2    Iezzi, S.3    King, M.T.4    Zhao, P.5    Kashiwaya, Y.6
  • 41
    • 0020617574 scopus 로고
    • Age-related differences in absolute numbers of skeletal muscle satellite cells
    • doi: 10.1002/mus.880060807
    • Gibson, M. C., and Schultz, E. (1983). Age-related differences in absolute numbers of skeletal muscle satellite cells. Muscle Nerve 6, 574-580. doi: 10.1002/mus.880060807.
    • (1983) Muscle Nerve , vol.6 , pp. 574-580
    • Gibson, M.C.1    Schultz, E.2
  • 42
    • 78349301557 scopus 로고    scopus 로고
    • Recent advances in the biology and therapy of muscle wasting
    • doi: 10.1111/j.1749-6632.2010.05809.x
    • Glass, D., and Roubenoff, R. (2010). Recent advances in the biology and therapy of muscle wasting. Ann. N.Y. Acad. Sci. 1211, 25-36. doi: 10.1111/j.1749-6632.2010.05809.x.
    • (2010) Ann. N.Y. Acad. Sci. , vol.1211 , pp. 25-36
    • Glass, D.1    Roubenoff, R.2
  • 43
    • 79952111161 scopus 로고    scopus 로고
    • PI3 kinase regulation of skeletal muscle hypertrophy and atrophy
    • doi: 10.1007/82_2010_78
    • Glass, D. J. (2010). PI3 kinase regulation of skeletal muscle hypertrophy and atrophy. Curr. Top. Microbiol. Immunol. 346, 267-278. doi: 10.1007/82_2010_78.
    • (2010) Curr. Top. Microbiol. Immunol. , vol.346 , pp. 267-278
    • Glass, D.J.1
  • 44
    • 0034107084 scopus 로고    scopus 로고
    • Thigh adipose tissue distribution is associated with insulin resistance in obesity and in type 2 diabetes mellitus
    • Goodpaster, B. H., Thaete, F. L., and Kelley, D. E. (2000a). Thigh adipose tissue distribution is associated with insulin resistance in obesity and in type 2 diabetes mellitus. Am. J. Clin. Nutr. 71, 885-892.
    • (2000) Am. J. Clin. Nutr. , vol.71 , pp. 885-892
    • Goodpaster, B.H.1    Thaete, F.L.2    Kelley, D.E.3
  • 45
    • 0034112806 scopus 로고    scopus 로고
    • Intramuscular lipid content is increased in obesity and decreased by weight loss
    • doi: 10.1016/S0026-0495(00)80010-4
    • Goodpaster, B. H., Theriault, R., Watkins, S. C., and Kelley, D. E. (2000b). Intramuscular lipid content is increased in obesity and decreased by weight loss. Metabolism 49, 467-472. doi: 10.1016/S0026-0495(00)80010-4.
    • (2000) Metabolism , vol.49 , pp. 467-472
    • Goodpaster, B.H.1    Theriault, R.2    Watkins, S.C.3    Kelley, D.E.4
  • 46
    • 11244329029 scopus 로고    scopus 로고
    • Skeletal muscle lipid accumulation in obesity, insulin resistance, and type 2 diabetes
    • doi: 10.1111/j.1399-543X.2004.00071.x
    • Goodpaster, B. H., and Wolf, D. (2004). Skeletal muscle lipid accumulation in obesity, insulin resistance, and type 2 diabetes. Pediatr. Diabetes 5, 219-226. doi: 10.1111/j.1399-543X.2004.00071.x.
    • (2004) Pediatr. Diabetes , vol.5 , pp. 219-226
    • Goodpaster, B.H.1    Wolf, D.2
  • 47
    • 0037218315 scopus 로고    scopus 로고
    • Wound healing and diabetes mellitus
    • doi: 10.1016/S0094-1298(02)00066-4
    • Greenhalgh, D. G. (2003). Wound healing and diabetes mellitus. Clin. Plast. Surg. 30, 37-45. doi: 10.1016/S0094-1298(02)00066-4.
    • (2003) Clin. Plast. Surg. , vol.30 , pp. 37-45
    • Greenhalgh, D.G.1
  • 48
    • 79953046341 scopus 로고    scopus 로고
    • Inflammatory mechanisms in obesity
    • doi: 10.1146/annurev-immunol-031210-101322
    • Gregor, M. F., and Hotamisligil, G. S. (2011). Inflammatory mechanisms in obesity. Annu. Rev. Immunol. 29, 415-445. doi: 10.1146/annurev-immunol-031210-101322.
    • (2011) Annu. Rev. Immunol. , vol.29 , pp. 415-445
    • Gregor, M.F.1    Hotamisligil, G.S.2
  • 49
    • 85027922510 scopus 로고    scopus 로고
    • Myf5-Positive Satellite Cells Contribute to Pax7-Dependent Long-Term Maintenance of Adult Muscle Stem Cells
    • doi: 10.1016/j.stem.2013.07.016
    • Gunther, S., Kim, J., Kostin, S., Lepper, C., Fan, C. M., and Braun, T. (2013). Myf5-Positive Satellite Cells Contribute to Pax7-Dependent Long-Term Maintenance of Adult Muscle Stem Cells. Cell Stem Cell. 13, 590-601. doi: 10.1016/j.stem.2013.07.016.
    • (2013) Cell Stem Cell. , vol.13 , pp. 590-601
    • Gunther, S.1    Kim, J.2    Kostin, S.3    Lepper, C.4    Fan, C.M.5    Braun, T.6
  • 50
    • 0035133331 scopus 로고    scopus 로고
    • Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells
    • doi: 10.1007/s001250051596
    • Hajduch, E., Balendran, A., Batty, I. H., Litherland, G. J., Blair, A. S., Downes, C. P., et al. (2001). Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells. Diabetologia 44, 173-183. doi: 10.1007/s001250051596.
    • (2001) Diabetologia , vol.44 , pp. 173-183
    • Hajduch, E.1    Balendran, A.2    Batty, I.H.3    Litherland, G.J.4    Blair, A.S.5    Downes, C.P.6
  • 51
    • 78651303072 scopus 로고    scopus 로고
    • Transcription activation of myostatin by trichostatin A in differentiated C2C12 myocytes via ASK1-MKK3/4/6-JNK and p38 mitogen-activated protein kinase pathways
    • doi: 10.1002/jcb.22740
    • Han, D. S., Huang, H. P., Wang, T. G., Hung, M. Y., Ke, J. Y., Chang, K. T., et al. (2010). Transcription activation of myostatin by trichostatin A in differentiated C2C12 myocytes via ASK1-MKK3/4/6-JNK and p38 mitogen-activated protein kinase pathways. J. Cell. Biochem. 111, 564-573. doi: 10.1002/jcb.22740.
    • (2010) J. Cell. Biochem. , vol.111 , pp. 564-573
    • Han, D.S.1    Huang, H.P.2    Wang, T.G.3    Hung, M.Y.4    Ke, J.Y.5    Chang, K.T.6
  • 52
    • 78449256948 scopus 로고    scopus 로고
    • Increased mitochondrial fatty acid oxidation is sufficient to protect skeletal muscle cells from palmitate-induced apoptosis
    • doi: 10.1074/jbc.M110.170431
    • Henique, C., Mansouri, A., Fumey, G., Lenoir, V., Girard, J., Bouillaud, F., et al. (2010). Increased mitochondrial fatty acid oxidation is sufficient to protect skeletal muscle cells from palmitate-induced apoptosis. J. Biol. Chem. 285, 36818-36827. doi: 10.1074/jbc.M110.170431.
    • (2010) J. Biol. Chem. , vol.285 , pp. 36818-36827
    • Henique, C.1    Mansouri, A.2    Fumey, G.3    Lenoir, V.4    Girard, J.5    Bouillaud, F.6
  • 53
    • 84876274371 scopus 로고    scopus 로고
    • Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration
    • doi: 10.1016/j.cell.2013.02.053
    • Heredia, J. E., Mukundan, L., Chen, F. M., Mueller, A. A., Deo, R. C., Locksley, R. M., et al. (2013). Type 2 innate signals stimulate fibro/adipogenic progenitors to facilitate muscle regeneration. Cell 153, 376-388. doi: 10.1016/j.cell.2013.02.053.
    • (2013) Cell , vol.153 , pp. 376-388
    • Heredia, J.E.1    Mukundan, L.2    Chen, F.M.3    Mueller, A.A.4    Deo, R.C.5    Locksley, R.M.6
  • 54
    • 55849105252 scopus 로고    scopus 로고
    • Excessive adipose tissue infiltration in skeletal muscle in individuals with obesity, diabetes mellitus, and peripheral neuropathy: association with performance and function
    • doi: 10.2522/ptj.20080079
    • Hilton, T. N., Tuttle, L. J., Bohnert, K. L., Mueller, M. J., and Sinacore, D. R. (2008). Excessive adipose tissue infiltration in skeletal muscle in individuals with obesity, diabetes mellitus, and peripheral neuropathy: association with performance and function. Phys. Ther. 88, 1336-1344. doi: 10.2522/ptj.20080079.
    • (2008) Phys. Ther. , vol.88 , pp. 1336-1344
    • Hilton, T.N.1    Tuttle, L.J.2    Bohnert, K.L.3    Mueller, M.J.4    Sinacore, D.R.5
  • 55
    • 63249100559 scopus 로고    scopus 로고
    • Increased secretion and expression of myostatin in skeletal muscle from extremely obese women
    • doi: 10.2337/db08-0943
    • Hittel, D. S., Berggren, J. R., Shearer, J., Boyle, K., and Houmard, J. A. (2009). Increased secretion and expression of myostatin in skeletal muscle from extremely obese women. Diabetes 58, 30-38. doi: 10.2337/db08-0943.
    • (2009) Diabetes , vol.58 , pp. 30-38
    • Hittel, D.S.1    Berggren, J.R.2    Shearer, J.3    Boyle, K.4    Houmard, J.A.5
  • 56
    • 33847332202 scopus 로고    scopus 로고
    • Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance
    • doi: 10.1016/j.cmet.2007.01.002
    • Holland, W. L., Brozinick, J. T., Wang, L. P., Hawkins, E. D., Sargent, K. M., Liu, Y., et al. (2007). Inhibition of ceramide synthesis ameliorates glucocorticoid-, saturated-fat-, and obesity-induced insulin resistance. Cell Metab. 5, 167-179. doi: 10.1016/j.cmet.2007.01.002.
    • (2007) Cell Metab. , vol.5 , pp. 167-179
    • Holland, W.L.1    Brozinick, J.T.2    Wang, L.P.3    Hawkins, E.D.4    Sargent, K.M.5    Liu, Y.6
  • 57
    • 77953183470 scopus 로고    scopus 로고
    • PTEN inhibition improves muscle regeneration in mice fed a high-fat diet
    • doi: 10.2337/db09-1155
    • Hu, Z., Wang, H., Lee, I. H., Modi, S., Wang, X., Du, J., et al. (2010). PTEN inhibition improves muscle regeneration in mice fed a high-fat diet. Diabetes 59, 1312-1320. doi: 10.2337/db09-1155.
    • (2010) Diabetes , vol.59 , pp. 1312-1320
    • Hu, Z.1    Wang, H.2    Lee, I.H.3    Modi, S.4    Wang, X.5    Du, J.6
  • 59
    • 14644417747 scopus 로고    scopus 로고
    • Ceramide down-regulates System A amino acid transport and protein synthesis in rat skeletal muscle cells
    • doi: 10.1096/fj.04-2284fje
    • Hyde, R., Hajduch, E., Powell, D. J., Taylor, P. M., and Hundal, H. S. (2005). Ceramide down-regulates System A amino acid transport and protein synthesis in rat skeletal muscle cells. FASEB J. 19, 461-463. doi: 10.1096/fj.04-2284fje.
    • (2005) FASEB J. , vol.19 , pp. 461-463
    • Hyde, R.1    Hajduch, E.2    Powell, D.J.3    Taylor, P.M.4    Hundal, H.S.5
  • 60
    • 84867623284 scopus 로고    scopus 로고
    • Satellite cell depletion does not inhibit adult skeletal muscle regrowth following unloading-induced atrophy
    • doi: 10.1152/ajpcell.00207.2012
    • Jackson, J. R., Mula, J., Kirby, T. J., Fry, C. S., Lee, J. D., Ubele, M. F., et al. (2012). Satellite cell depletion does not inhibit adult skeletal muscle regrowth following unloading-induced atrophy. Am. J. Physiol. Cell. Physiol. 303, C854-C861. doi: 10.1152/ajpcell.00207.2012.
    • (2012) Am. J. Physiol. Cell. Physiol. , vol.303
    • Jackson, J.R.1    Mula, J.2    Kirby, T.J.3    Fry, C.S.4    Lee, J.D.5    Ubele, M.F.6
  • 61
    • 84867410773 scopus 로고    scopus 로고
    • Skeletal muscle stem cells: effects of aging and metabolism on muscle regenerative function
    • doi: 10.1101/sqb.2011.76.010652
    • Jang, Y. C., Sinha, M., Cerletti, M., Dall'osso, C., and Wagers, A. J. (2011). Skeletal muscle stem cells: effects of aging and metabolism on muscle regenerative function. Cold Spring Harb. Symp. Quant. Biol. 76, 101-111. doi: 10.1101/sqb.2011.76.010652.
    • (2011) Cold Spring Harb. Symp. Quant. Biol. , vol.76 , pp. 101-111
    • Jang, Y.C.1    Sinha, M.2    Cerletti, M.3    Dall'osso, C.4    Wagers, A.J.5
  • 62
    • 75949096894 scopus 로고    scopus 로고
    • Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis
    • doi: 10.1038/ncb2015
    • Joe, A. W., Yi, L., Natarajan, A., Le Grand, F., So, L., Wang, J., Rudnicki, M. A., et al. (2010). Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis. Nat. Cell. Biol. 12, 153-163. doi: 10.1038/ncb2015.
    • (2010) Nat. Cell. Biol. , vol.12 , pp. 153-163
    • Joe, A.W.1    Yi, L.2    Natarajan, A.3    Le Grand, F.4    So, L.5    Wang, J.6    Rudnicki, M.A.7
  • 63
    • 33745854176 scopus 로고    scopus 로고
    • Myostatin regulation of muscle development: molecular basis, natural mutations, physiopathological aspects
    • doi: 10.1016/j.yexcr.2006.04.012
    • Joulia-Ekaza, D., and Cabello, G. (2006). Myostatin regulation of muscle development: molecular basis, natural mutations, physiopathological aspects. Exp. Cell. Res. 312, 2401-2414. doi: 10.1016/j.yexcr.2006.04.012.
    • (2006) Exp. Cell. Res. , vol.312 , pp. 2401-2414
    • Joulia-Ekaza, D.1    Cabello, G.2
  • 64
    • 0038636430 scopus 로고    scopus 로고
    • Mechanisms involved in the inhibition of myoblast proliferation and differentiation by myostatin
    • doi: 10.1016/S0014-4827(03)00074-0
    • Joulia, D., Bernardi, H., Garandel, V., Rabenoelina, F., Vernus, B., and Cabello, G. (2003). Mechanisms involved in the inhibition of myoblast proliferation and differentiation by myostatin. Exp. Cell. Res. 286, 263-275. doi: 10.1016/S0014-4827(03)00074-0.
    • (2003) Exp. Cell. Res. , vol.286 , pp. 263-275
    • Joulia, D.1    Bernardi, H.2    Garandel, V.3    Rabenoelina, F.4    Vernus, B.5    Cabello, G.6
  • 65
    • 4444338265 scopus 로고    scopus 로고
    • The effects of heavy resistance training and detraining on satellite cells in human skeletal muscles
    • doi: 10.1113/jphysiol.2004.065904
    • Kadi, F., Schjerling, P., Andersen, L. L., Charifi, N., Madsen, J. L., Christensen, L. R., et al. (2004). The effects of heavy resistance training and detraining on satellite cells in human skeletal muscles. J. Physiol. 558, 1005-1012. doi: 10.1113/jphysiol.2004.065904.
    • (2004) J. Physiol. , vol.558 , pp. 1005-1012
    • Kadi, F.1    Schjerling, P.2    Andersen, L.L.3    Charifi, N.4    Madsen, J.L.5    Christensen, L.R.6
  • 66
    • 33845881411 scopus 로고    scopus 로고
    • Mechanisms linking obesity to insulin resistance and type 2 diabetes
    • doi: 10.1038/nature05482
    • Kahn, S. E., Hull, R. L., and Utzschneider, K. M. (2006). Mechanisms linking obesity to insulin resistance and type 2 diabetes. Nature 444, 840-846. doi: 10.1038/nature05482.
    • (2006) Nature , vol.444 , pp. 840-846
    • Kahn, S.E.1    Hull, R.L.2    Utzschneider, K.M.3
  • 67
    • 0030828823 scopus 로고    scopus 로고
    • Leptin activates PI-3 kinase in C2C12 myotubes via janus kinase-2 (JAK-2) and insulin receptor substrate-2 (IRS-2) dependent pathways
    • doi: 10.1007/s001250050832
    • Kellerer, M., Koch, M., Metzinger, E., Mushack, J., Capp, E., and Haring, H. U. (1997). Leptin activates PI-3 kinase in C2C12 myotubes via janus kinase-2 (JAK-2) and insulin receptor substrate-2 (IRS-2) dependent pathways. Diabetologia 40, 1358-1362. doi: 10.1007/s001250050832.
    • (1997) Diabetologia , vol.40 , pp. 1358-1362
    • Kellerer, M.1    Koch, M.2    Metzinger, E.3    Mushack, J.4    Capp, E.5    Haring, H.U.6
  • 68
    • 84874534408 scopus 로고    scopus 로고
    • Macrophage plasticity and the role of inflammation in skeletal muscle repair
    • doi: 10.1155/2013/491497
    • Kharraz, Y., Guerra, J., Mann, C. J., Serrano, A. L., and Munoz-Canoves, P. (2013). Macrophage plasticity and the role of inflammation in skeletal muscle repair. Mediators Inflamm. 2013, 491497. doi: 10.1155/2013/491497.
    • (2013) Mediators Inflamm. , vol.2013 , pp. 491497
    • Kharraz, Y.1    Guerra, J.2    Mann, C.J.3    Serrano, A.L.4    Munoz-Canoves, P.5
  • 69
    • 0034457883 scopus 로고    scopus 로고
    • In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin
    • doi: 10.1210/en.141.7.2328
    • Kim, Y. B., Uotani, S., Pierroz, D. D., Flier, J. S., and Kahn, B. B. (2000). In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin. Endocrinology 141, 2328-2339. doi: 10.1210/en.141.7.2328.
    • (2000) Endocrinology , vol.141 , pp. 2328-2339
    • Kim, Y.B.1    Uotani, S.2    Pierroz, D.D.3    Flier, J.S.4    Kahn, B.B.5
  • 70
    • 41549084155 scopus 로고    scopus 로고
    • Transforming growth factor-beta and myostatin signaling in skeletal muscle
    • doi: 10.1152/japplphysiol.01091.2007
    • Kollias, H. D., and McDermott, J. C. (2008). Transforming growth factor-beta and myostatin signaling in skeletal muscle. J. Appl. Physiol. 104, 579-587. doi: 10.1152/japplphysiol.01091.2007.
    • (2008) J. Appl. Physiol. , vol.104 , pp. 579-587
    • Kollias, H.D.1    McDermott, J.C.2
  • 71
    • 0037219256 scopus 로고    scopus 로고
    • Intramyocellular lipid and insulin resistance: a longitudinal in vivo 1H-spectroscopic study in Zucker diabetic fatty rats
    • doi: 10.2337/diabetes.52.1.138
    • Kuhlmann, J., Neumann-Haefelin, C., Belz, U., Kalisch, J., Juretschke, H. P., Stein, M., et al. (2003). Intramyocellular lipid and insulin resistance: a longitudinal in vivo 1H-spectroscopic study in Zucker diabetic fatty rats. Diabetes 52, 138-144. doi: 10.2337/diabetes.52.1.138.
    • (2003) Diabetes , vol.52 , pp. 138-144
    • Kuhlmann, J.1    Neumann-Haefelin, C.2    Belz, U.3    Kalisch, J.4    Juretschke, H.P.5    Stein, M.6
  • 72
    • 0024405776 scopus 로고
    • The Zucker fatty rat as a genetic model of obesity and hypertension
    • doi: 10.1161/01.HYP.13.6.896
    • Kurtz, T. W., Morris, R. C., and Pershadsingh, H. A. (1989). The Zucker fatty rat as a genetic model of obesity and hypertension. Hypertension 13, 896-901. doi: 10.1161/01.HYP.13.6.896.
    • (1989) Hypertension , vol.13 , pp. 896-901
    • Kurtz, T.W.1    Morris, R.C.2    Pershadsingh, H.A.3
  • 73
    • 70449133334 scopus 로고    scopus 로고
    • Diabetes and apoptosis: lipotoxicity
    • doi: 10.1007/s10495-009-0352-8
    • Kusminski, C. M., Shetty, S., Orci, L., Unger, R. H., and Scherer, P. E. (2009). Diabetes and apoptosis: lipotoxicity. Apoptosis 14, 1484-1495. doi: 10.1007/s10495-009-0352-8.
    • (2009) Apoptosis , vol.14 , pp. 1484-1495
    • Kusminski, C.M.1    Shetty, S.2    Orci, L.3    Unger, R.H.4    Scherer, P.E.5
  • 75
    • 0035020963 scopus 로고    scopus 로고
    • Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-kappaB
    • doi: 10.1096/fj.00-0463
    • Langen, R. C., Schols, A. M., Kelders, M. C., Wouters, E. F., and Janssen-Heininger, Y. M. (2001). Inflammatory cytokines inhibit myogenic differentiation through activation of nuclear factor-kappaB. FASEB J. 15, 1169-1180. doi: 10.1096/fj.00-0463.
    • (2001) FASEB J. , vol.15 , pp. 1169-1180
    • Langen, R.C.1    Schols, A.M.2    Kelders, M.C.3    Wouters, E.F.4    Janssen-Heininger, Y.M.5
  • 76
    • 0037147210 scopus 로고    scopus 로고
    • Myostatin inhibits myoblast differentiation by down-regulating MyoD expression
    • doi: 10.1074/jbc.M204291200
    • Langley, B., Thomas, M., Bishop, A., Sharma, M., Gilmour, S., and Kambadur, R. (2002). Myostatin inhibits myoblast differentiation by down-regulating MyoD expression. J. Biol. Chem. 277, 49831-49840. doi: 10.1074/jbc.M204291200.
    • (2002) J. Biol. Chem. , vol.277 , pp. 49831-49840
    • Langley, B.1    Thomas, M.2    Bishop, A.3    Sharma, M.4    Gilmour, S.5    Kambadur, R.6
  • 77
    • 65549109680 scopus 로고    scopus 로고
    • Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss
    • doi: 10.1016/j.jacc.2008.12.068
    • Lavie, C. J., Milani, R. V., and Ventura, H. O. (2009). Obesity and cardiovascular disease: risk factor, paradox, and impact of weight loss. J. Am. Coll. Cardiol. 53, 1925-1932. doi: 10.1016/j.jacc.2008.12.068.
    • (2009) J. Am. Coll. Cardiol. , vol.53 , pp. 1925-1932
    • Lavie, C.J.1    Milani, R.V.2    Ventura, H.O.3
  • 78
    • 0033602762 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha and basic fibroblast growth factor differentially inhibit the insulin-like growth factor-I induced expression of myogenin in C2C12 myoblasts
    • doi: 10.1006/excr.1999.4465
    • Layne, M. D., and Farmer, S. R. (1999). Tumor necrosis factor-alpha and basic fibroblast growth factor differentially inhibit the insulin-like growth factor-I induced expression of myogenin in C2C12 myoblasts. Exp. Cell Res. 249, 177-187. doi: 10.1006/excr.1999.4465.
    • (1999) Exp. Cell Res. , vol.249 , pp. 177-187
    • Layne, M.D.1    Farmer, S.R.2
  • 79
    • 84870811605 scopus 로고    scopus 로고
    • Relationships between insulin sensitivity, skeletal muscle mass and muscle quality in obese adolescent boys
    • doi: 10.1038/ejcn.2012.142
    • Lee, S., Kim, Y., White, D. A., Kuk, J. L., and Arslanian, S. (2012a). Relationships between insulin sensitivity, skeletal muscle mass and muscle quality in obese adolescent boys. Eur. J. Clin. Nutr. 66, 1366-1368. doi: 10.1038/ejcn.2012.142.
    • (2012) Eur. J. Clin. Nutr. , vol.66 , pp. 1366-1368
    • Lee, S.1    Kim, Y.2    White, D.A.3    Kuk, J.L.4    Arslanian, S.5
  • 80
    • 84865531266 scopus 로고    scopus 로고
    • Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway
    • doi: 10.1073/pnas.1206410109
    • Lee, S. J., Huynh, T. V., Lee, Y. S., Sebald, S. M., Wilcox-Adelman, S. A., Iwamori, N., et al. (2012b). Role of satellite cells versus myofibers in muscle hypertrophy induced by inhibition of the myostatin/activin signaling pathway. Proc. Natl. Acad. Sci. U.S.A. 109, E2353-E2360. doi: 10.1073/pnas.1206410109.
    • (2012) Proc. Natl. Acad. Sci. U.S.A. , vol.109
    • Lee, S.J.1    Huynh, T.V.2    Lee, Y.S.3    Sebald, S.M.4    Wilcox-Adelman, S.A.5    Iwamori, N.6
  • 81
    • 84878368561 scopus 로고    scopus 로고
    • Measurements of diacylglycerols in skeletal muscle by atmospheric pressure chemical ionization mass spectrometry
    • doi: 10.1007/s11745-013-3766-6
    • Lee, S. Y., Kim, J. R., Ha, M. Y., Shim, S. M., and Park, T. S. (2013). Measurements of diacylglycerols in skeletal muscle by atmospheric pressure chemical ionization mass spectrometry. Lipids 48, 287-296. doi: 10.1007/s11745-013-3766-6.
    • (2013) Lipids , vol.48 , pp. 287-296
    • Lee, S.Y.1    Kim, J.R.2    Ha, M.Y.3    Shim, S.M.4    Park, T.S.5
  • 82
    • 12444334643 scopus 로고    scopus 로고
    • Lipotoxicity, an imbalance between lipogenesis de novo and fatty acid oxidation
    • doi: 10.1038/sj.ijo.0802854
    • Lelliott, C., and Vidal-Puig, A. J. (2004). Lipotoxicity, an imbalance between lipogenesis de novo and fatty acid oxidation. Int. J. Obes. Relat. Metab. Disord. 28(Suppl. 4), S22-S28. doi: 10.1038/sj.ijo.0802854.
    • (2004) Int. J. Obes. Relat. Metab. Disord. , vol.28 , Issue.SUPPL. 4
    • Lelliott, C.1    Vidal-Puig, A.J.2
  • 83
    • 80051483036 scopus 로고    scopus 로고
    • An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration
    • doi: 10.1242/dev.067595
    • Lepper, C., Partridge, T. A., and Fan, C. M. (2011). An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration. Development 138, 3639-3646. doi: 10.1242/dev.067595.
    • (2011) Development , vol.138 , pp. 3639-3646
    • Lepper, C.1    Partridge, T.A.2    Fan, C.M.3
  • 84
    • 84867090688 scopus 로고    scopus 로고
    • Macrophages improve survival, proliferation and migration of engrafted myogenic precursor cells into MDX skeletal muscle
    • doi: 10.1371/journal.pone.0046698
    • Lesault, P. F., Theret, M., Magnan, M., Cuvellier, S., Niu, Y., Gherardi, R. K., et al. (2012). Macrophages improve survival, proliferation and migration of engrafted myogenic precursor cells into MDX skeletal muscle. PLoS ONE 7:e46698. doi: 10.1371/journal.pone.0046698.
    • (2012) PLoS ONE , vol.7
    • Lesault, P.F.1    Theret, M.2    Magnan, M.3    Cuvellier, S.4    Niu, Y.5    Gherardi, R.K.6
  • 85
    • 0029142737 scopus 로고
    • Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice
    • doi: 10.1172/JCI118145
    • Levak-Frank, S., Radner, H., Walsh, A., Stollberger, R., Knipping, G., Hoefler, G., et al. (1995). Muscle-specific overexpression of lipoprotein lipase causes a severe myopathy characterized by proliferation of mitochondria and peroxisomes in transgenic mice. J. Clin. Invest. 96, 976-986. doi: 10.1172/JCI118145.
    • (1995) J. Clin. Invest. , vol.96 , pp. 976-986
    • Levak-Frank, S.1    Radner, H.2    Walsh, A.3    Stollberger, R.4    Knipping, G.5    Hoefler, G.6
  • 86
    • 8544233570 scopus 로고    scopus 로고
    • Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101)
    • doi: 10.1074/jbc.C400186200
    • Li, Y., Soos, T. J., Li, X., Wu, J., Degennaro, M., Sun, X., et al. (2004). Protein kinase C Theta inhibits insulin signaling by phosphorylating IRS1 at Ser(1101). J. Biol. Chem. 279, 45304-45307. doi: 10.1074/jbc.C400186200.
    • (2004) J. Biol. Chem. , vol.279 , pp. 45304-45307
    • Li, Y.1    Soos, T.J.2    Li, X.3    Wu, J.4    Degennaro, M.5    Sun, X.6
  • 87
    • 0042242879 scopus 로고    scopus 로고
    • TNF-alpha is a mitogen in skeletal muscle
    • doi: 10.1152/ajpcell.00453.2002
    • Li, Y. P. (2003). TNF-alpha is a mitogen in skeletal muscle. Am. J. Physiol. Cell Physiol. 285, C370-C376. doi: 10.1152/ajpcell.00453.2002.
    • (2003) Am. J. Physiol. Cell Physiol. , vol.285
    • Li, Y.P.1
  • 88
    • 0035890328 scopus 로고    scopus 로고
    • TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3
    • doi: 10.1101/gad.925901
    • Liu, D., Black, B. L., and Derynck, R. (2001). TGF-beta inhibits muscle differentiation through functional repression of myogenic transcription factors by Smad3. Genes Dev. 15, 2950-2966. doi: 10.1101/gad.925901.
    • (2001) Genes Dev. , vol.15 , pp. 2950-2966
    • Liu, D.1    Black, B.L.2    Derynck, R.3
  • 89
    • 84856850591 scopus 로고    scopus 로고
    • PKC theta ablation improves healing in a mouse model of muscular dystrophy
    • doi: 10.1371/journal.pone.0031515
    • Madaro, L., Pelle, A., Nicoletti, C., Crupi, A., Marrocco, V., Bossi, G., et al. (2012). PKC theta ablation improves healing in a mouse model of muscular dystrophy. PLoS ONE 7:e31515. doi: 10.1371/journal.pone.0031515.
    • (2012) PLoS ONE , vol.7
    • Madaro, L.1    Pelle, A.2    Nicoletti, C.3    Crupi, A.4    Marrocco, V.5    Bossi, G.6
  • 90
    • 0028845877 scopus 로고
    • Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
    • doi: 10.1038/nm1195-1155
    • Maffei, M., Halaas, J., Ravussin, E., Pratley, R. E., Lee, G. H., Zhang, Y., et al. (1995). Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects. Nat. Med. 1, 1155-1161. doi: 10.1038/nm1195-1155.
    • (1995) Nat. Med. , vol.1 , pp. 1155-1161
    • Maffei, M.1    Halaas, J.2    Ravussin, E.3    Pratley, R.E.4    Lee, G.H.5    Zhang, Y.6
  • 91
    • 58149286361 scopus 로고    scopus 로고
    • TOF-SIMS analysis of lipid accumulation in the skeletal muscle of ob/ob mice
    • doi: 10.1038/oby.2008.424
    • Magnusson, Y. K., Friberg, P., Sjovall, P., Malm, J., and Chen, Y. (2008). TOF-SIMS analysis of lipid accumulation in the skeletal muscle of ob/ob mice. Obesity (Silver Spring) 16, 2745-2753. doi: 10.1038/oby.2008.424.
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 2745-2753
    • Magnusson, Y.K.1    Friberg, P.2    Sjovall, P.3    Malm, J.4    Chen, Y.5
  • 93
    • 84856721921 scopus 로고    scopus 로고
    • Aberrant repair and fibrosis development in skeletal muscle
    • doi: 10.1186/2044-5040-1-21
    • Mann, C. J., Perdiguero, E., Kharraz, Y., Aguilar, S., Pessina, P., Serrano, A. L., et al. (2011). Aberrant repair and fibrosis development in skeletal muscle. Skelet. Muscle 1, 21. doi: 10.1186/2044-5040-1-21.
    • (2011) Skelet. Muscle , vol.1 , pp. 21
    • Mann, C.J.1    Perdiguero, E.2    Kharraz, Y.3    Aguilar, S.4    Pessina, P.5    Serrano, A.L.6
  • 94
    • 84884326083 scopus 로고    scopus 로고
    • Suppression of protein kinase C theta contributes to enhanced myogenesis in vitro via IRS1 and ERK1/2 phosphorylation
    • doi: 10.1186/1471-2121-14-39
    • Marino, J. S., Hinds, T. D. Jr., Potter, R. A., Ondrus, E., Onion, J. L., Dowling, A., et al. (2013). Suppression of protein kinase C theta contributes to enhanced myogenesis in vitro via IRS1 and ERK1/2 phosphorylation. BMC Cell Biol. 14:39. doi: 10.1186/1471-2121-14-39.
    • (2013) BMC Cell Biol. , vol.14 , pp. 39
    • Marino, J.S.1    Hinds Jr., T.D.2    Potter, R.A.3    Ondrus, E.4    Onion, J.L.5    Dowling, A.6
  • 95
    • 0037471205 scopus 로고    scopus 로고
    • Early intracellular events induced by in vivo leptin treatment in mouse skeletal muscle
    • doi: 10.1016/S0303-7207(02)00427-6
    • Maroni, P., Bendinelli, P., and Piccoletti, R. (2003). Early intracellular events induced by in vivo leptin treatment in mouse skeletal muscle. Mol. Cell Endocrinol. 201, 109-121. doi: 10.1016/S0303-7207(02)00427-6.
    • (2003) Mol. Cell Endocrinol. , vol.201 , pp. 109-121
    • Maroni, P.1    Bendinelli, P.2    Piccoletti, R.3
  • 96
    • 19744367530 scopus 로고    scopus 로고
    • Intracellular signal transduction pathways induced by leptin in C2C12 cells
    • doi: 10.1016/j.cellbi.2005.03.008
    • Maroni, P., Bendinelli, P., and Piccoletti, R. (2005). Intracellular signal transduction pathways induced by leptin in C2C12 cells. Cell. Biol. Int. 29, 542-550. doi: 10.1016/j.cellbi.2005.03.008.
    • (2005) Cell. Biol. Int. , vol.29 , pp. 542-550
    • Maroni, P.1    Bendinelli, P.2    Piccoletti, R.3
  • 97
    • 3342919078 scopus 로고    scopus 로고
    • Fiber type-and fatty acid composition-dependent effects of high-fat diets on rat muscle triacylglyceride and fatty acid transporter protein-1 content
    • doi: 10.1016/j.metabol.2004.03.011
    • Marotta, M., Ferrer-Martnez, A., Parnau, J., Turini, M., Mace, K., and Gomez Foix, A. M. (2004). Fiber type-and fatty acid composition-dependent effects of high-fat diets on rat muscle triacylglyceride and fatty acid transporter protein-1 content. Metabolism 53, 1032-1036. doi: 10.1016/j.metabol.2004.03.011.
    • (2004) Metabolism , vol.53 , pp. 1032-1036
    • Marotta, M.1    Ferrer-Martnez, A.2    Parnau, J.3    Turini, M.4    Mace, K.5    Gomez Foix, A.M.6
  • 98
    • 52949129178 scopus 로고    scopus 로고
    • Leptin resistance: a possible interface of inflammation and metabolism in obesity-related cardiovascular disease
    • doi: 10.1016/j.jacc.2008.05.060
    • Martin, S. S., Qasim, A., and Reilly, M. P. (2008). Leptin resistance: a possible interface of inflammation and metabolism in obesity-related cardiovascular disease. J. Am. Coll. Cardiol. 52, 1201-1210. doi: 10.1016/j.jacc.2008.05.060.
    • (2008) J. Am. Coll. Cardiol. , vol.52 , pp. 1201-1210
    • Martin, S.S.1    Qasim, A.2    Reilly, M.P.3
  • 99
    • 0031587959 scopus 로고    scopus 로고
    • ED2+ macrophages increase selectively myoblast proliferation in muscle cultures
    • doi: 10.1006/bbrc.1997.6823
    • Massimino, M. L., Rapizzi, E., Cantini, M., Libera, L. D., Mazzoleni, F., Arslan, P., et al. (1997). ED2+ macrophages increase selectively myoblast proliferation in muscle cultures. Biochem. Biophys. Res. Commun. 235, 754-759. doi: 10.1006/bbrc.1997.6823.
    • (1997) Biochem. Biophys. Res. Commun. , vol.235 , pp. 754-759
    • Massimino, M.L.1    Rapizzi, E.2    Cantini, M.3    Libera, L.D.4    Mazzoleni, F.5    Arslan, P.6
  • 100
    • 80051512193 scopus 로고    scopus 로고
    • Effective fiber hypertrophy in satellite cell-depleted skeletal muscle
    • doi: 10.1242/dev.068858
    • McCarthy, J. J., Mula, J., Miyazaki, M., Erfani, R., Garrison, K., Farooqui, A. B., et al. (2011). Effective fiber hypertrophy in satellite cell-depleted skeletal muscle. Development 138, 3657-3666. doi: 10.1242/dev.068858.
    • (2011) Development , vol.138 , pp. 3657-3666
    • McCarthy, J.J.1    Mula, J.2    Miyazaki, M.3    Erfani, R.4    Garrison, K.5    Farooqui, A.B.6
  • 101
    • 0141768237 scopus 로고    scopus 로고
    • Myostatin negatively regulates satellite cell activation and self-renewal
    • doi: 10.1083/jcb.200207056
    • McCroskery, S., Thomas, M., Maxwell, L., Sharma, M., and Kambadur, R. (2003). Myostatin negatively regulates satellite cell activation and self-renewal. J. Cell. Biol. 162, 1135-1147. doi: 10.1083/jcb.200207056.
    • (2003) J. Cell. Biol. , vol.162 , pp. 1135-1147
    • McCroskery, S.1    Thomas, M.2    Maxwell, L.3    Sharma, M.4    Kambadur, R.5
  • 102
    • 33847408400 scopus 로고    scopus 로고
    • Inhibition of de novo ceramide synthesis upregulates phospholipase D and enhances myogenic differentiation
    • doi: 10.1242/jcs.03331
    • Mebarek, S., Komati, H., Naro, F., Zeiller, C., Alvisi, M., Lagarde, M., et al. (2007). Inhibition of de novo ceramide synthesis upregulates phospholipase D and enhances myogenic differentiation. J. Cell. Sci. 120, 407-416. doi: 10.1242/jcs.03331.
    • (2007) J. Cell. Sci. , vol.120 , pp. 407-416
    • Mebarek, S.1    Komati, H.2    Naro, F.3    Zeiller, C.4    Alvisi, M.5    Lagarde, M.6
  • 103
    • 0033060101 scopus 로고    scopus 로고
    • Macrophages enhance muscle satellite cell proliferation and delay their differentiation
    • doi: 10.1002/(SICI)1097-4598(199906)22:6<724::AID-MUS9^gt;3.0.CO;2-O
    • Merly, F., Lescaudron, L., Rouaud, T., Crossin, F., and Gardahaut, M. F. (1999). Macrophages enhance muscle satellite cell proliferation and delay their differentiation. Muscle Nerve 22, 724-732. doi: 10.1002/(SICI)1097-4598(199906)22:6<724::AID-MUS9^gt;3.0.CO;2-O.
    • (1999) Muscle Nerve , vol.22 , pp. 724-732
    • Merly, F.1    Lescaudron, L.2    Rouaud, T.3    Crossin, F.4    Gardahaut, M.F.5
  • 104
    • 35948949462 scopus 로고    scopus 로고
    • VEGF overexpression via adeno-associated virus gene transfer promotes skeletal muscle regeneration and enhances muscle function in mdx mice
    • doi: 10.1096/fj.07-8459com
    • Messina, S., Mazzeo, A., Bitto, A., Aguennouz, M., Migliorato, A., De Pasquale, M. G., et al. (2007). VEGF overexpression via adeno-associated virus gene transfer promotes skeletal muscle regeneration and enhances muscle function in mdx mice. FASEB J. 21, 3737-3746. doi: 10.1096/fj.07-8459com.
    • (2007) FASEB J. , vol.21 , pp. 3737-3746
    • Messina, S.1    Mazzeo, A.2    Bitto, A.3    Aguennouz, M.4    Migliorato, A.5    De Pasquale, M.G.6
  • 105
    • 0023924058 scopus 로고
    • Tumor necrosis factor inhibits human myogenesis in vitro
    • Miller, S. C., Ito, H., Blau, H. M., and Torti, F. M. (1988). Tumor necrosis factor inhibits human myogenesis in vitro. Mol. Cell Biol. 8, 2295-2301.
    • (1988) Mol. Cell Biol. , vol.8 , pp. 2295-2301
    • Miller, S.C.1    Ito, H.2    Blau, H.M.3    Torti, F.M.4
  • 106
    • 70349496577 scopus 로고    scopus 로고
    • Relationship between body fat mass and free fatty acid kinetics in men and women
    • doi: 10.1038/oby.2009.224
    • Mittendorfer, B., Magkos, F., Fabbrini, E., Mohammed, B. S., and Klein, S. (2009). Relationship between body fat mass and free fatty acid kinetics in men and women. Obesity (Silver Spring) 17, 1872-1877. doi: 10.1038/oby.2009.224.
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 1872-1877
    • Mittendorfer, B.1    Magkos, F.2    Fabbrini, E.3    Mohammed, B.S.4    Klein, S.5
  • 107
    • 84860406420 scopus 로고    scopus 로고
    • Impaired muscle regeneration in ob/ob and db/db mice
    • doi: 10.1100/tsw.2011.137
    • Nguyen, M. H., Cheng, M., and Koh, T. J. (2011). Impaired muscle regeneration in ob/ob and db/db mice. ScientificWorldJournal 11, 1525-1535. doi: 10.1100/tsw.2011.137.
    • (2011) ScientificWorldJournal , vol.11 , pp. 1525-1535
    • Nguyen, M.H.1    Cheng, M.2    Koh, T.J.3
  • 108
    • 34547619196 scopus 로고    scopus 로고
    • Delayed angiogenesis and VEGF production in CCR2-/-mice during impaired skeletal muscle regeneration
    • doi: 10.1152/ajpregu.00069.2007
    • Ochoa, O., Sun, D., Reyes-Reyna, S. M., Waite, L. L., Michalek, J. E., McManus, L. M., et al. (2007). Delayed angiogenesis and VEGF production in CCR2-/-mice during impaired skeletal muscle regeneration. Am. J. Physiol. Regul. Integr. Comp. Physiol. 293, R651-R661. doi: 10.1152/ajpregu.00069.2007.
    • (2007) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.293
    • Ochoa, O.1    Sun, D.2    Reyes-Reyna, S.M.3    Waite, L.L.4    Michalek, J.E.5    McManus, L.M.6
  • 109
    • 73949151878 scopus 로고    scopus 로고
    • Impaired overload-induced hypertrophy in obese Zucker rat slow-twitch skeletal muscle
    • doi: 10.1152/japplphysiol.00330.2009
    • Paturi, S., Gutta, A. K., Kakarla, S. K., Katta, A., Arnold, E. C., Wu, M., et al. (2010). Impaired overload-induced hypertrophy in obese Zucker rat slow-twitch skeletal muscle. J. Appl. Physiol. 108, 7-13. doi: 10.1152/japplphysiol.00330.2009.
    • (2010) J. Appl. Physiol. , vol.108 , pp. 7-13
    • Paturi, S.1    Gutta, A.K.2    Kakarla, S.K.3    Katta, A.4    Arnold, E.C.5    Wu, M.6
  • 110
    • 84872420583 scopus 로고    scopus 로고
    • Muscle side population cells from dystrophic or injured muscle adopt a fibro-adipogenic fate
    • doi: 10.1371/journal.pone.0054553
    • Penton, C. M., Thomas-Ahner, J. M., Johnson, E. K., McAllister, C., and Montanaro, F. (2013). Muscle side population cells from dystrophic or injured muscle adopt a fibro-adipogenic fate. PLOS ONE 8:e54553. doi: 10.1371/journal.pone.0054553.
    • (2013) PLOS ONE , vol.8
    • Penton, C.M.1    Thomas-Ahner, J.M.2    Johnson, E.K.3    McAllister, C.4    Montanaro, F.5
  • 111
    • 55949101805 scopus 로고    scopus 로고
    • Satellite cell proliferation is reduced in muscles of obese Zucker rats but restored with loading
    • doi: 10.1152/ajpcell.00073.2008
    • Peterson, J. M., Bryner, R. W., and Alway, S. E. (2008a). Satellite cell proliferation is reduced in muscles of obese Zucker rats but restored with loading. Am. J. Physiol. Cell Physiol. 295, C521-C528. doi: 10.1152/ajpcell.00073.2008.
    • (2008) Am. J. Physiol. Cell Physiol. , vol.295
    • Peterson, J.M.1    Bryner, R.W.2    Alway, S.E.3
  • 112
    • 57549106453 scopus 로고    scopus 로고
    • Bax signaling regulates palmitate-mediated apoptosis in C(2)C(12) myotubes
    • doi: 10.1152/ajpendo.00738.2007
    • Peterson, J. M., Wang, Y., Bryner, R. W., Williamson, D. L., and Alway, S. E. (2008b). Bax signaling regulates palmitate-mediated apoptosis in C(2)C(12) myotubes. Am. J. Physiol. Endocrinol. Metab. 295, E1307-E1314. doi: 10.1152/ajpendo.00738.2007.
    • (2008) Am. J. Physiol. Endocrinol. Metab. , vol.295
    • Peterson, J.M.1    Wang, Y.2    Bryner, R.W.3    Williamson, D.L.4    Alway, S.E.5
  • 113
    • 49649118005 scopus 로고    scopus 로고
    • Potent myofiber hypertrophy during resistance training in humans is associated with satellite cell-mediated myonuclear addition: a cluster analysis
    • doi: 10.1152/japplphysiol.01215.2007
    • Petrella, J. K., Kim, J. S., Mayhew, D. L., Cross, J. M., and Bamman, M. M. (2008). Potent myofiber hypertrophy during resistance training in humans is associated with satellite cell-mediated myonuclear addition: a cluster analysis. J. Appl. Physiol. (1985) 104, 1736-1742. doi: 10.1152/japplphysiol.01215.2007.
    • (2008) J. Appl. Physiol. (1985) , vol.104 , pp. 1736-1742
    • Petrella, J.K.1    Kim, J.S.2    Mayhew, D.L.3    Cross, J.M.4    Bamman, M.M.5
  • 114
    • 84873182170 scopus 로고    scopus 로고
    • Leptin impairs myogenesis in C2C12 cells through JAK/STAT and MEK signaling pathways
    • doi: 10.1016/j.cyto.2012.11.002
    • Pijet, M., Pijet, B., Litwiniuk, A., Pajak, B., Gajkowska, B., and Orzechowski, A. (2013). Leptin impairs myogenesis in C2C12 cells through JAK/STAT and MEK signaling pathways. Cytokine 61, 445-454. doi: 10.1016/j.cyto.2012.11.002.
    • (2013) Cytokine , vol.61 , pp. 445-454
    • Pijet, M.1    Pijet, B.2    Litwiniuk, A.3    Pajak, B.4    Gajkowska, B.5    Orzechowski, A.6
  • 115
    • 0142091454 scopus 로고    scopus 로고
    • Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism
    • doi: 10.1128/MCB.23.21.7794-7808.2003
    • Powell, D. J., Hajduch, E., Kular, G., and Hundal, H. S. (2003). Ceramide disables 3-phosphoinositide binding to the pleckstrin homology domain of protein kinase B (PKB)/Akt by a PKCzeta-dependent mechanism. Mol. Cell Biol. 23, 7794-7808. doi: 10.1128/MCB.23.21.7794-7808.2003.
    • (2003) Mol. Cell Biol. , vol.23 , pp. 7794-7808
    • Powell, D.J.1    Hajduch, E.2    Kular, G.3    Hundal, H.S.4
  • 116
    • 4544242908 scopus 로고    scopus 로고
    • Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells
    • doi: 10.1042/BJ20040139
    • Powell, D. J., Turban, S., Gray, A., Hajduch, E., and Hundal, H. S. (2004). Intracellular ceramide synthesis and protein kinase Czeta activation play an essential role in palmitate-induced insulin resistance in rat L6 skeletal muscle cells. Biochem. J. 382, 619-629. doi: 10.1042/BJ20040139.
    • (2004) Biochem. J. , vol.382 , pp. 619-629
    • Powell, D.J.1    Turban, S.2    Gray, A.3    Hajduch, E.4    Hundal, H.S.5
  • 117
    • 0022039121 scopus 로고
    • Muscle growth and satellite cell proliferative activity in obese (OB/OB) mice
    • Purchas, R. W., Romsos, D. R., Allen, R. E., and Merkel, R. A. (1985). Muscle growth and satellite cell proliferative activity in obese (OB/OB) mice. J. Anim. Sci. 60, 644-651.
    • (1985) J. Anim. Sci. , vol.60 , pp. 644-651
    • Purchas, R.W.1    Romsos, D.R.2    Allen, R.E.3    Merkel, R.A.4
  • 118
    • 33845895308 scopus 로고    scopus 로고
    • Palmitate induced mitochondrial deoxyribonucleic acid damage and apoptosis in l6 rat skeletal muscle cells
    • doi: 10.1210/en.2006-0998
    • Rachek, L. I., Musiyenko, S. I., Ledoux, S. P., and Wilson, G. L. (2007). Palmitate induced mitochondrial deoxyribonucleic acid damage and apoptosis in l6 rat skeletal muscle cells. Endocrinology 148, 293-299. doi: 10.1210/en.2006-0998.
    • (2007) Endocrinology , vol.148 , pp. 293-299
    • Rachek, L.I.1    Musiyenko, S.I.2    Ledoux, S.P.3    Wilson, G.L.4
  • 119
    • 33846194248 scopus 로고    scopus 로고
    • Duchenne muscular dystrophy: focus on pharmaceutical and nutritional interventions
    • doi: 10.1016/j.biocel.2006.09.009
    • Radley, H. G., De Luca, A., Lynch, G. S., and Grounds, M. D. (2007). Duchenne muscular dystrophy: focus on pharmaceutical and nutritional interventions. Int. J. Biochem. Cell Biol. 39, 469-477. doi: 10.1016/j.biocel.2006.09.009.
    • (2007) Int. J. Biochem. Cell Biol. , vol.39 , pp. 469-477
    • Radley, H.G.1    De Luca, A.2    Lynch, G.S.3    Grounds, M.D.4
  • 120
    • 0036854487 scopus 로고    scopus 로고
    • Leptin potentiates IFN-gamma-induced expression of nitric oxide synthase and cyclo-oxygenase-2 in murine macrophage J774A.1
    • doi: 10.1038/sj.bjp.0704903
    • Raso, G. M., Pacilio, M., Esposito, E., Coppola, A., Di Carlo, R., and Meli, R. (2002). Leptin potentiates IFN-gamma-induced expression of nitric oxide synthase and cyclo-oxygenase-2 in murine macrophage J774A.1. Br. J. Pharmacol. 137, 799-804. doi: 10.1038/sj.bjp.0704903.
    • (2002) Br. J. Pharmacol. , vol.137 , pp. 799-804
    • Raso, G.M.1    Pacilio, M.2    Esposito, E.3    Coppola, A.4    Di Carlo, R.5    Meli, R.6
  • 121
    • 0028818456 scopus 로고
    • Satellite cells and myonuclei in long-term denervated rat muscles
    • doi: 10.1002/ar.1092430405
    • Rodrigues Ade, C., and Schmalbruch, H. (1995). Satellite cells and myonuclei in long-term denervated rat muscles. Anat. Rec. 243, 430-437. doi: 10.1002/ar.1092430405.
    • (1995) Anat. Rec. , vol.243 , pp. 430-437
    • Rodrigues Ade, C.1    Schmalbruch, H.2
  • 122
    • 0028338899 scopus 로고
    • Satellite cell activity is required for hypertrophy of overloaded adult rat muscle
    • doi: 10.1002/mus.880170607
    • Rosenblatt, J. D., Yong, D., and Parry, D. J. (1994). Satellite cell activity is required for hypertrophy of overloaded adult rat muscle. Muscle Nerve 17, 608-613. doi: 10.1002/mus.880170607.
    • (1994) Muscle Nerve , vol.17 , pp. 608-613
    • Rosenblatt, J.D.1    Yong, D.2    Parry, D.J.3
  • 123
    • 84868250231 scopus 로고    scopus 로고
    • The role of sirtuins in the regulation of metabolic homeostasis in skeletal muscle
    • doi: 10.1097/MCO.0b013e3283590914
    • Ryall, J. G. (2012). The role of sirtuins in the regulation of metabolic homeostasis in skeletal muscle. Curr. Opin. Clin. Nutr. Metab. Care 15, 561-566. doi: 10.1097/MCO.0b013e3283590914.
    • (2012) Curr. Opin. Clin. Nutr. Metab. Care , vol.15 , pp. 561-566
    • Ryall, J.G.1
  • 124
    • 84882618900 scopus 로고    scopus 로고
    • Metabolic reprogramming as a novel regulator of skeletal muscle development and regeneration
    • doi: 10.1111/febs.12189
    • Ryall, J. G. (2013). Metabolic reprogramming as a novel regulator of skeletal muscle development and regeneration. FEBS J 280, 4004-4013. doi: 10.1111/febs.12189.
    • (2013) FEBS J , vol.280 , pp. 4004-4013
    • Ryall, J.G.1
  • 125
    • 70149104583 scopus 로고    scopus 로고
    • Leptin administration favors muscle mass accretion by decreasing FoxO3a and increasing PGC-1alpha in ob/ob mice
    • doi: 10.1371/journal.pone.0006808
    • Sainz, N., Rodriguez, A., Catalan, V., Becerril, S., Ramirez, B., Gomez-Ambrosi, J., et al. (2009). Leptin administration favors muscle mass accretion by decreasing FoxO3a and increasing PGC-1alpha in ob/ob mice. PLoS ONE 4:e6808. doi: 10.1371/journal.pone.0006808.
    • (2009) PLoS ONE , vol.4
    • Sainz, N.1    Rodriguez, A.2    Catalan, V.3    Becerril, S.4    Ramirez, B.5    Gomez-Ambrosi, J.6
  • 126
    • 33747041041 scopus 로고    scopus 로고
    • The effect of glutamine on prevention of glucocorticoid-induced skeletal muscle atrophy is associated with myostatin suppression
    • doi: 10.1016/j.metabol.2006.05.009
    • Salehian, B., Mahabadi, V., Bilas, J., Taylor, W. E., and Ma, K. (2006). The effect of glutamine on prevention of glucocorticoid-induced skeletal muscle atrophy is associated with myostatin suppression. Metabolism 55, 1239-1247. doi: 10.1016/j.metabol.2006.05.009.
    • (2006) Metabolism , vol.55 , pp. 1239-1247
    • Salehian, B.1    Mahabadi, V.2    Bilas, J.3    Taylor, W.E.4    Ma, K.5
  • 127
    • 0342980927 scopus 로고    scopus 로고
    • Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells
    • doi: 10.1006/mcne.1999.0813
    • Salinas, M., Lopez-Valdaliso, R., Martin, D., Alvarez, A., and Cuadrado, A. (2000). Inhibition of PKB/Akt1 by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells. Mol. Cell. Neurosci. 15, 156-169. doi: 10.1006/mcne.1999.0813.
    • (2000) Mol. Cell. Neurosci. , vol.15 , pp. 156-169
    • Salinas, M.1    Lopez-Valdaliso, R.2    Martin, D.3    Alvarez, A.4    Cuadrado, A.5
  • 128
    • 77953868236 scopus 로고    scopus 로고
    • Lipid-induced insulin resistance: unravelling the mechanism
    • doi: 10.1016/S0140-6736(10)60408-4
    • Samuel, V. T., Petersen, K. F., and Shulman, G. I. (2010). Lipid-induced insulin resistance: unravelling the mechanism. Lancet 375, 2267-2277. doi: 10.1016/S0140-6736(10)60408-4.
    • (2010) Lancet , vol.375 , pp. 2267-2277
    • Samuel, V.T.1    Petersen, K.F.2    Shulman, G.I.3
  • 129
    • 84857861919 scopus 로고    scopus 로고
    • Mechanisms for insulin resistance: common threads and missing links
    • doi: 10.1016/j.cell.2012.02.017
    • Samuel, V. T., and Shulman, G. I. (2012). Mechanisms for insulin resistance: common threads and missing links. Cell 148, 852-871. doi: 10.1016/j.cell.2012.02.017.
    • (2012) Cell , vol.148 , pp. 852-871
    • Samuel, V.T.1    Shulman, G.I.2
  • 130
    • 0033602850 scopus 로고    scopus 로고
    • Human leptin stimulates proliferation and activation of human circulating monocytes
    • doi: 10.1006/cimm.1999.1490
    • Santos-Alvarez, J., Goberna, R., and Sanchez-Margalet, V. (1999). Human leptin stimulates proliferation and activation of human circulating monocytes. Cell. Immunol. 194, 6-11. doi: 10.1006/cimm.1999.1490.
    • (1999) Cell. Immunol. , vol.194 , pp. 6-11
    • Santos-Alvarez, J.1    Goberna, R.2    Sanchez-Margalet, V.3
  • 131
    • 4043140199 scopus 로고    scopus 로고
    • Molecular and cellular determinants of skeletal muscle atrophy and hypertrophy
    • doi: 10.1126/stke.2442004re11
    • Sartorelli, V., and Fulco, M. (2004). Molecular and cellular determinants of skeletal muscle atrophy and hypertrophy. Sci. STKE 2004, re11. doi: 10.1126/stke.2442004re11.
    • (2004) Sci. STKE , vol.2004
    • Sartorelli, V.1    Fulco, M.2
  • 132
    • 0028987309 scopus 로고
    • Skeletal muscle glycolytic and oxidative enzyme capacities are determinants of insulin sensitivity and muscle composition in obese women
    • Simoneau, J. A., Colberg, S. R., Thaete, F. L., and Kelley, D. E. (1995). Skeletal muscle glycolytic and oxidative enzyme capacities are determinants of insulin sensitivity and muscle composition in obese women. FASEB J. 9, 273-278.
    • (1995) FASEB J. , vol.9 , pp. 273-278
    • Simoneau, J.A.1    Colberg, S.R.2    Thaete, F.L.3    Kelley, D.E.4
  • 133
    • 0036224883 scopus 로고    scopus 로고
    • Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: relationships to insulin sensitivity, total body fat, and central adiposity
    • doi: 10.2337/diabetes.51.4.1022
    • Sinha, R., Dufour, S., Petersen, K. F., Lebon, V., Enoksson, S., Ma, Y. Z., et al. (2002). Assessment of skeletal muscle triglyceride content by (1)H nuclear magnetic resonance spectroscopy in lean and obese adolescents: relationships to insulin sensitivity, total body fat, and central adiposity. Diabetes 51, 1022-1027. doi: 10.2337/diabetes.51.4.1022.
    • (2002) Diabetes , vol.51 , pp. 1022-1027
    • Sinha, R.1    Dufour, S.2    Petersen, K.F.3    Lebon, V.4    Enoksson, S.5    Ma, Y.Z.6
  • 134
    • 78751535748 scopus 로고    scopus 로고
    • Diet-induced obesity alters signalling pathways and induces atrophy and apoptosis in skeletal muscle in a prediabetic rat model
    • doi: 10.1113/expphysiol.2010.054189
    • Sishi, B., Loos, B., Ellis, B., Smith, W., Du Toit, E. F., and Engelbrecht, A. M. (2011). Diet-induced obesity alters signalling pathways and induces atrophy and apoptosis in skeletal muscle in a prediabetic rat model. Exp. Physiol. 96, 179-193. doi: 10.1113/expphysiol.2010.054189.
    • (2011) Exp. Physiol. , vol.96 , pp. 179-193
    • Sishi, B.1    Loos, B.2    Ellis, B.3    Smith, W.4    Du Toit, E.F.5    Engelbrecht, A.M.6
  • 135
    • 71249106254 scopus 로고    scopus 로고
    • Chronic high fat feeding attenuates load-induced hypertrophy in mice
    • doi: 10.1113/jphysiol.2009.180174
    • Sitnick, M., Bodine, S. C., and Rutledge, J. C. (2009). Chronic high fat feeding attenuates load-induced hypertrophy in mice. J. Physiol. 587, 5753-5765. doi: 10.1113/jphysiol.2009.180174.
    • (2009) J. Physiol. , vol.587 , pp. 5753-5765
    • Sitnick, M.1    Bodine, S.C.2    Rutledge, J.C.3
  • 136
    • 0036787911 scopus 로고    scopus 로고
    • The myostatin gene is a downstream target gene of basic helix-loop-helix transcription factor MyoD
    • doi: 10.1128/MCB.22.20.7066-7082.2002
    • Spiller, M. P., Kambadur, R., Jeanplong, F., Thomas, M., Martyn, J. K., Bass, J. J., et al. (2002). The myostatin gene is a downstream target gene of basic helix-loop-helix transcription factor MyoD. Mol. Cell Biol. 22, 7066-7082. doi: 10.1128/MCB.22.20.7066-7082.2002.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 7066-7082
    • Spiller, M.P.1    Kambadur, R.2    Jeanplong, F.3    Thomas, M.4    Martyn, J.K.5    Bass, J.J.6
  • 137
    • 4344614649 scopus 로고    scopus 로고
    • Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B
    • doi: 10.1074/jbc.M406499200
    • Stratford, S., Hoehn, K. L., Liu, F., and Summers, S. A. (2004). Regulation of insulin action by ceramide: dual mechanisms linking ceramide accumulation to the inhibition of Akt/protein kinase B. J. Biol. Chem. 279, 36608-36615. doi: 10.1074/jbc.M406499200.
    • (2004) J. Biol. Chem. , vol.279 , pp. 36608-36615
    • Stratford, S.1    Hoehn, K.L.2    Liu, F.3    Summers, S.A.4
  • 138
    • 4644221064 scopus 로고    scopus 로고
    • Proinflammatory cytokine impairment of insulin-like growth factor I-induced protein synthesis in skeletal muscle myoblasts requires ceramide
    • doi: 10.1210/en.2003-1749
    • Strle, K., Broussard, S. R., McCusker, R. H., Shen, W. H., Johnson, R. W., Freund, G. G., et al. (2004). Proinflammatory cytokine impairment of insulin-like growth factor I-induced protein synthesis in skeletal muscle myoblasts requires ceramide. Endocrinology 145, 4592-4602. doi: 10.1210/en.2003-1749.
    • (2004) Endocrinology , vol.145 , pp. 4592-4602
    • Strle, K.1    Broussard, S.R.2    McCusker, R.H.3    Shen, W.H.4    Johnson, R.W.5    Freund, G.G.6
  • 139
    • 84864871850 scopus 로고    scopus 로고
    • Skeletal muscle damage and impaired regeneration due to LPL-mediated lipotoxicity
    • doi: 10.1038/cddis.2012.91
    • Tamilarasan, K. P., Temmel, H., Das, S. K., Al Zoughbi, W., Schauer, S., Vesely, P. W., et al. (2012). Skeletal muscle damage and impaired regeneration due to LPL-mediated lipotoxicity. Cell Death Dis. 3, e354. doi: 10.1038/cddis.2012.91.
    • (2012) Cell Death Dis. , vol.3
    • Tamilarasan, K.P.1    Temmel, H.2    Das, S.K.3    Al Zoughbi, W.4    Schauer, S.5    Vesely, P.W.6
  • 141
    • 47149111389 scopus 로고    scopus 로고
    • Cell biology of lipid droplets
    • doi: 10.1016/j.ceb.2008.05.009
    • Thiele, C., and Spandl, J. (2008). Cell biology of lipid droplets. Curr. Opin. Cell Biol. 20, 378-385. doi: 10.1016/j.ceb.2008.05.009.
    • (2008) Curr. Opin. Cell Biol. , vol.20 , pp. 378-385
    • Thiele, C.1    Spandl, J.2
  • 142
    • 0034704106 scopus 로고    scopus 로고
    • Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation
    • doi: 10.1074/jbc.M004356200
    • Thomas, M., Langley, B., Berry, C., Sharma, M., Kirk, S., Bass, J., et al. (2000). Myostatin, a negative regulator of muscle growth, functions by inhibiting myoblast proliferation. J. Biol. Chem. 275, 40235-40243. doi: 10.1074/jbc.M004356200.
    • (2000) J. Biol. Chem. , vol.275 , pp. 40235-40243
    • Thomas, M.1    Langley, B.2    Berry, C.3    Sharma, M.4    Kirk, S.5    Bass, J.6
  • 143
    • 42949084209 scopus 로고    scopus 로고
    • Muscular diacylglycerol metabolism and insulin resistance
    • doi: 10.1016/j.physbeh.2007.12.002
    • Timmers, S., Schrauwen, P., and De Vogel, J. (2008). Muscular diacylglycerol metabolism and insulin resistance. Physiol. Behav. 94, 242-251. doi: 10.1016/j.physbeh.2007.12.002.
    • (2008) Physiol. Behav. , vol.94 , pp. 242-251
    • Timmers, S.1    Schrauwen, P.2    De Vogel, J.3
  • 144
    • 0037242916 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha (TNF-alpha) stimulates chemotactic response in mouse myogenic cells
    • doi: 10.3727/000000003783985115
    • Torrente, Y., El Fahime, E., Caron, N. J., Del Bo, R., Belicchi, M., Pisati, F., et al. (2003). Tumor necrosis factor-alpha (TNF-alpha) stimulates chemotactic response in mouse myogenic cells. Cell Transplant. 12, 91-100. doi: 10.3727/000000003783985115.
    • (2003) Cell Transplant. , vol.12 , pp. 91-100
    • Torrente, Y.1    El Fahime, E.2    Caron, N.J.3    Del Bo, R.4    Belicchi, M.5    Pisati, F.6
  • 145
    • 79952428226 scopus 로고    scopus 로고
    • IL-6 induced STAT3 signalling is associated with the proliferation of human muscle satellite cells following acute muscle damage
    • doi: 10.1371/journal.pone.0017392
    • Toth, K. G., McKay, B. R., De Lisio, M., Little, J. P., Tarnopolsky, M. A., and Parise, G. (2011). IL-6 induced STAT3 signalling is associated with the proliferation of human muscle satellite cells following acute muscle damage. PLoS ONE 6:e17392. doi: 10.1371/journal.pone.0017392.
    • (2011) PLoS ONE , vol.6
    • Toth, K.G.1    McKay, B.R.2    De Lisio, M.3    Little, J.P.4    Tarnopolsky, M.A.5    Parise, G.6
  • 146
    • 84863881200 scopus 로고    scopus 로고
    • TAK-1/p38/nNFkappaB signaling inhibits myoblast differentiation by increasing levels of Activin A
    • doi: 10.1186/2044-5040-2-3
    • Trendelenburg, A. U., Meyer, A., Jacobi, C., Feige, J. N., and Glass, D. J. (2012). TAK-1/p38/nNFkappaB signaling inhibits myoblast differentiation by increasing levels of Activin A. Skelet. Muscle 2, 3. doi: 10.1186/2044-5040-2-3.
    • (2012) Skelet. Muscle , vol.2 , pp. 3
    • Trendelenburg, A.U.1    Meyer, A.2    Jacobi, C.3    Feige, J.N.4    Glass, D.J.5
  • 147
    • 0034832176 scopus 로고    scopus 로고
    • Rodent obesity models: an overview
    • doi: 10.1055/s-2001-17297
    • Tschop, M., and Heiman, M. L. (2001). Rodent obesity models: an overview. Exp. Clin. Endocrinol. Diabetes 109, 307-319. doi: 10.1055/s-2001-17297.
    • (2001) Exp. Clin. Endocrinol. Diabetes , vol.109 , pp. 307-319
    • Tschop, M.1    Heiman, M.L.2
  • 148
    • 78651376861 scopus 로고    scopus 로고
    • Protein kinase C isoforms: mediators of reactive lipid metabolites in the development of insulin resistance
    • doi: 10.1016/j.febslet.2010.12.022
    • Turban, S., and Hajduch, E. (2011). Protein kinase C isoforms: mediators of reactive lipid metabolites in the development of insulin resistance. FEBS Lett. 585, 269-274. doi: 10.1016/j.febslet.2010.12.022.
    • (2011) FEBS Lett. , vol.585 , pp. 269-274
    • Turban, S.1    Hajduch, E.2
  • 149
    • 0025317854 scopus 로고
    • 1,2-Diacylglycerol and ceramide levels in rat skeletal muscle and liver in vivo. Studies with insulin, exercise, muscle denervation, and vasopressin
    • Turinsky, J., Bayly, B. P., and O'Sullivan, D. M. (1990). 1,2-Diacylglycerol and ceramide levels in rat skeletal muscle and liver in vivo. Studies with insulin, exercise, muscle denervation, and vasopressin. J. Biol. Chem. 265, 7933-7938.
    • (1990) J. Biol. Chem. , vol.265 , pp. 7933-7938
    • Turinsky, J.1    Bayly, B.P.2    O'Sullivan, D.M.3
  • 150
    • 84878871217 scopus 로고    scopus 로고
    • Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding
    • doi: 10.1007/s00125-013-2913-1
    • Turner, N., Kowalski, G. M., Leslie, S. J., Risis, S., Yang, C., Lee-Young, R. S., et al. (2013). Distinct patterns of tissue-specific lipid accumulation during the induction of insulin resistance in mice by high-fat feeding. Diabetologia 56, 1638-1648. doi: 10.1007/s00125-013-2913-1.
    • (2013) Diabetologia , vol.56 , pp. 1638-1648
    • Turner, N.1    Kowalski, G.M.2    Leslie, S.J.3    Risis, S.4    Yang, C.5    Lee-Young, R.S.6
  • 151
    • 33845401821 scopus 로고    scopus 로고
    • Apoptosis in skeletal muscle myotubes is induced by ceramides and is positively related to insulin resistance
    • doi: 10.1152/ajpendo.00095.2006
    • Turpin, S. M., Lancaster, G. I., Darby, I., Febbraio, M. A., and Watt, M. J. (2006). Apoptosis in skeletal muscle myotubes is induced by ceramides and is positively related to insulin resistance. Am. J. Physiol. Endocrinol. Metab. 291, E1341-E1350. doi: 10.1152/ajpendo.00095.2006.
    • (2006) Am. J. Physiol. Endocrinol. Metab. , vol.291
    • Turpin, S.M.1    Lancaster, G.I.2    Darby, I.3    Febbraio, M.A.4    Watt, M.J.5
  • 152
    • 63849125553 scopus 로고    scopus 로고
    • Examination of 'lipotoxicity' in skeletal muscle of high-fat fed and ob/ob mice
    • doi: 10.1113/jphysiol.2008.166033
    • Turpin, S. M., Ryall, J. G., Southgate, R., Darby, I., Hevener, A. L., Febbraio, M. A., et al. (2009). Examination of 'lipotoxicity' in skeletal muscle of high-fat fed and ob/ob mice. J. Physiol. 587, 1593-1605. doi: 10.1113/jphysiol.2008.166033.
    • (2009) J. Physiol. , vol.587 , pp. 1593-1605
    • Turpin, S.M.1    Ryall, J.G.2    Southgate, R.3    Darby, I.4    Hevener, A.L.5    Febbraio, M.A.6
  • 153
    • 75949130333 scopus 로고    scopus 로고
    • Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle
    • doi: 10.1038/ncb2014
    • Uezumi, A., Fukada, S., Yamamoto, N., Takeda, S., and Tsuchida, K. (2010). Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle. Nat. Cell Biol. 12, 143-152. doi: 10.1038/ncb2014.
    • (2010) Nat. Cell Biol. , vol.12 , pp. 143-152
    • Uezumi, A.1    Fukada, S.2    Yamamoto, N.3    Takeda, S.4    Tsuchida, K.5
  • 154
    • 0345374579 scopus 로고    scopus 로고
    • Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome
    • doi: 10.1210/en.2003-0870
    • Unger, R. H. (2003). Minireview: weapons of lean body mass destruction: the role of ectopic lipids in the metabolic syndrome. Endocrinology 144, 5159-5165. doi: 10.1210/en.2003-0870.
    • (2003) Endocrinology , vol.144 , pp. 5159-5165
    • Unger, R.H.1
  • 155
    • 76049091112 scopus 로고    scopus 로고
    • Lipid homeostasis, lipotoxicity and the metabolic syndrome
    • doi: 10.1016/j.bbalip.2009.10.006
    • Unger, R. H., Clark, G. O., Scherer, P. E., and Orci, L. (2010). Lipid homeostasis, lipotoxicity and the metabolic syndrome. Biochim. Biophys. Acta 1801, 209-214. doi: 10.1016/j.bbalip.2009.10.006.
    • (2010) Biochim. Biophys. Acta , vol.1801 , pp. 209-214
    • Unger, R.H.1    Clark, G.O.2    Scherer, P.E.3    Orci, L.4
  • 156
    • 77956022194 scopus 로고    scopus 로고
    • Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption
    • doi: 10.2337/db09-1293
    • Ussher, J. R., Koves, T. R., Cadete, V. J., Zhang, L., Jaswal, J. S., Swyrd, S. J., et al. (2010). Inhibition of de novo ceramide synthesis reverses diet-induced insulin resistance and enhances whole-body oxygen consumption. Diabetes 59, 2453-2464. doi: 10.2337/db09-1293.
    • (2010) Diabetes , vol.59 , pp. 2453-2464
    • Ussher, J.R.1    Koves, T.R.2    Cadete, V.J.3    Zhang, L.4    Jaswal, J.S.5    Swyrd, S.J.6
  • 157
    • 42949116365 scopus 로고    scopus 로고
    • Lipid accumulation in non-adipose tissue and lipotoxicity
    • doi: 10.1016/j.physbeh.2007.11.049
    • Van Herpen, N. A., and Schrauwen-Hinderling, V. B. (2008). Lipid accumulation in non-adipose tissue and lipotoxicity. Physiol. Behav. 94, 231-241. doi: 10.1016/j.physbeh.2007.11.049.
    • (2008) Physiol. Behav. , vol.94 , pp. 231-241
    • Van Herpen, N.A.1    Schrauwen-Hinderling, V.B.2
  • 158
    • 80555131148 scopus 로고    scopus 로고
    • Diabetic neuropathy: cellular mechanisms as therapeutic targets
    • doi: 10.1038/nrneurol.2011.137
    • Vincent, A. M., Callaghan, B. C., Smith, A. L., and Feldman, E. L. (2011). Diabetic neuropathy: cellular mechanisms as therapeutic targets. Nat. Rev. Neurol. 7, 573-583. doi: 10.1038/nrneurol.2011.137.
    • (2011) Nat. Rev. Neurol. , vol.7 , pp. 573-583
    • Vincent, A.M.1    Callaghan, B.C.2    Smith, A.L.3    Feldman, E.L.4
  • 159
    • 39149121154 scopus 로고    scopus 로고
    • Effects of interleukin-6, leukemia inhibitory factor, and ciliary neurotrophic factor on the proliferation and differentiation of adult human myoblasts
    • doi: 10.1007/s10571-007-9247-9
    • Wang, X., Wu, H., Zhang, Z., Liu, S., Yang, J., Chen, X., et al. (2008). Effects of interleukin-6, leukemia inhibitory factor, and ciliary neurotrophic factor on the proliferation and differentiation of adult human myoblasts. Cell Mol. Neurobiol. 28, 113-124. doi: 10.1007/s10571-007-9247-9.
    • (2008) Cell Mol. Neurobiol. , vol.28 , pp. 113-124
    • Wang, X.1    Wu, H.2    Zhang, Z.3    Liu, S.4    Yang, J.5    Chen, X.6
  • 160
    • 84856096512 scopus 로고    scopus 로고
    • Satellite cells, the engines of muscle repair
    • doi: 10.1038/nrm3265
    • Wang, Y. X., and Rudnicki, M. A. (2012). Satellite cells, the engines of muscle repair. Nat. Rev. Mol. Cell Biol. 13, 127-133. doi: 10.1038/nrm3265.
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 127-133
    • Wang, Y.X.1    Rudnicki, M.A.2
  • 161
    • 14644430904 scopus 로고    scopus 로고
    • Chemokine receptor CCR2 involvement in skeletal muscle regeneration
    • doi: 10.1096/fj.04-2421fje
    • Warren, G. L., Hulderman, T., Mishra, D., Gao, X., Millecchia, L., O'Farrell, L., et al. (2005). Chemokine receptor CCR2 involvement in skeletal muscle regeneration. FASEB J. 19, 413-415. doi: 10.1096/fj.04-2421fje.
    • (2005) FASEB J. , vol.19 , pp. 413-415
    • Warren, G.L.1    Hulderman, T.2    Mishra, D.3    Gao, X.4    Millecchia, L.5    O'Farrell, L.6
  • 162
    • 34447279283 scopus 로고    scopus 로고
    • Mechanisms of skeletal muscle injury and repair revealed by gene expression studies in mouse models
    • doi: 10.1113/jphysiol.2007.132373
    • Warren, G. L., Summan, M., Gao, X., Chapman, R., Hulderman, T., and Simeonova, P. P. (2007). Mechanisms of skeletal muscle injury and repair revealed by gene expression studies in mouse models. J. Physiol. 582, 825-841. doi: 10.1113/jphysiol.2007.132373.
    • (2007) J. Physiol. , vol.582 , pp. 825-841
    • Warren, G.L.1    Summan, M.2    Gao, X.3    Chapman, R.4    Hulderman, T.5    Simeonova, P.P.6
  • 163
    • 84876467243 scopus 로고    scopus 로고
    • Increased Smad signaling and reduced MRF expression in skeletal muscle from obese subjects
    • doi: 10.1002/oby.20070
    • Watts, R., McAinch, A. J., Dixon, J. B., O'Brien, P. E., and Cameron-Smith, D. (2013). Increased Smad signaling and reduced MRF expression in skeletal muscle from obese subjects. Obesity (Silver Spring) 21, 525-528. doi: 10.1002/oby.20070.
    • (2013) Obesity (Silver Spring) , vol.21 , pp. 525-528
    • Watts, R.1    McAinch, A.J.2    Dixon, J.B.3    O'Brien, P.E.4    Cameron-Smith, D.5
  • 164
    • 18244370762 scopus 로고    scopus 로고
    • Inflammation, stress, and diabetes
    • doi: 10.1172/JCI200525102
    • Wellen, K. E., and Hotamisligil, G. S. (2005). Inflammation, stress, and diabetes. J. Clin. Invest. 115, 1111-1119. doi: 10.1172/JCI200525102.
    • (2005) J. Clin. Invest. , vol.115 , pp. 1111-1119
    • Wellen, K.E.1    Hotamisligil, G.S.2
  • 165
    • 84867398854 scopus 로고    scopus 로고
    • Effects of leptin and adiponectin on proliferation and protein metabolism of porcine myoblasts
    • doi: 10.1007/s00418-012-0949-9
    • Will, K., Kalbe, C., Kuzinski, J., Losel, D., Viergutz, T., Palin, M. F., et al. (2012). Effects of leptin and adiponectin on proliferation and protein metabolism of porcine myoblasts. Histochem. Cell Biol. 138, 271-287. doi: 10.1007/s00418-012-0949-9.
    • (2012) Histochem. Cell Biol. , vol.138 , pp. 271-287
    • Will, K.1    Kalbe, C.2    Kuzinski, J.3    Losel, D.4    Viergutz, T.5    Palin, M.F.6
  • 166
    • 80053428731 scopus 로고    scopus 로고
    • Early life nutrition modulates muscle stem cell number: implications for muscle mass and repair
    • doi: 10.1089/scd.2010.0349
    • Woo, M., Isganaitis, E., Cerletti, M., Fitzpatrick, C., Wagers, A. J., Jimenez-Chillaron, J., et al. (2011). Early life nutrition modulates muscle stem cell number: implications for muscle mass and repair. Stem Cells Dev. 20, 1763-1769. doi: 10.1089/scd.2010.0349.
    • (2011) Stem Cells Dev. , vol.20 , pp. 1763-1769
    • Woo, M.1    Isganaitis, E.2    Cerletti, M.3    Fitzpatrick, C.4    Wagers, A.J.5    Jimenez-Chillaron, J.6
  • 167
    • 43749091658 scopus 로고    scopus 로고
    • World Health Organization. WHO Media Centre. Geneva, Switzerland.
    • World Health Organization. (2013). Obesity and overweight Fact Sheet N°311. WHO Media Centre. Geneva, Switzerland.
    • (2013) Obesity and overweight Fact Sheet N°311
  • 168
    • 84855331167 scopus 로고    scopus 로고
    • Longitudinal evaluation of intramyocellular lipids (IMCLs) in tibialis anterior muscle of ob/ob and ob/+ control mice using a cryogenic surface coil at 9.4 T
    • doi: 10.1002/nbm.1691
    • Ye, Q., Danzer, C. F., Fuchs, A., Krek, W., Mueggler, T., Baltes, C., et al. (2011). Longitudinal evaluation of intramyocellular lipids (IMCLs) in tibialis anterior muscle of ob/ob and ob/+ control mice using a cryogenic surface coil at 9.4 T. NMR Biomed. 24, 1295-1301. doi: 10.1002/nbm.1691.
    • (2011) NMR Biomed. , vol.24 , pp. 1295-1301
    • Ye, Q.1    Danzer, C.F.2    Fuchs, A.3    Krek, W.4    Mueggler, T.5    Baltes, C.6
  • 169
    • 80054694342 scopus 로고    scopus 로고
    • Peripheral vascular disease and peripheral neuropathy in individuals with cardiometabolic clustering and obesity: National Health and Nutrition Examination Survey 2001-2004
    • doi: 10.2337/dc10-2150
    • Ylitalo, K. R., Sowers, M., and Heeringa, S. (2011). Peripheral vascular disease and peripheral neuropathy in individuals with cardiometabolic clustering and obesity: National Health and Nutrition Examination Survey 2001-2004. Diabetes Care 34, 1642-1647. doi: 10.2337/dc10-2150.
    • (2011) Diabetes Care , vol.34 , pp. 1642-1647
    • Ylitalo, K.R.1    Sowers, M.2    Heeringa, S.3
  • 170
    • 0037184925 scopus 로고    scopus 로고
    • Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
    • doi: 10.1074/jbc.M200958200
    • Yu, C., Chen, Y., Cline, G. W., Zhang, D., Zong, H., Wang, Y., et al. (2002). Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle. J. Biol. Chem. 277, 50230-50236. doi: 10.1074/jbc.M200958200.
    • (2002) J. Biol. Chem. , vol.277 , pp. 50230-50236
    • Yu, C.1    Chen, Y.2    Cline, G.W.3    Zhang, D.4    Zong, H.5    Wang, Y.6
  • 171
    • 78649660058 scopus 로고    scopus 로고
    • Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress
    • doi: 10.1152/ajpendo.00238.2010
    • Yuzefovych, L., Wilson, G., and Rachek, L. (2010). Different effects of oleate vs. palmitate on mitochondrial function, apoptosis, and insulin signaling in L6 skeletal muscle cells: role of oxidative stress. Am. J. Physiol. Endocrinol. Metab. 299, E1096-E1105. doi: 10.1152/ajpendo.00238.2010.
    • (2010) Am. J. Physiol. Endocrinol. Metab. , vol.299
    • Yuzefovych, L.1    Wilson, G.2    Rachek, L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.