-
1
-
-
0021994683
-
Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulindependent (type II) diabetes mellitus
-
DeFronzo RA, Gunnarsson R, Bjorkman O, Olsson M, Wahren J: Effects of insulin on peripheral and splanchnic glucose metabolism in noninsulindependent (type II) diabetes mellitus. J Clin Invest 76:149-155, 1985
-
(1985)
J Clin Invest
, vol.76
, pp. 149-155
-
-
DeFronzo, R.A.1
Gunnarsson, R.2
Bjorkman, O.3
Olsson, M.4
Wahren, J.5
-
2
-
-
0022977709
-
Fat feeding causes widespread in vivo insulin resistance, decreased energy expenditure and obesity in the rat
-
Storlien LH, James DE, Burleigh KM, Chisholm DJ, Kraegen EW: Fat feeding causes widespread in vivo insulin resistance, decreased energy expenditure and obesity in the rat. Am J Physiol 251: E576-E583, 1986
-
(1986)
Am J Physiol
, vol.251
-
-
Storlien, L.H.1
James, D.E.2
Burleigh, K.M.3
Chisholm, D.J.4
Kraegen, E.W.5
-
3
-
-
0029874313
-
Abdominal fat and insulin resistance in normal and overweight women: Direct measurements reveal a strong relationship in subjects at both low and high risk of NIDDM
-
Carey DG, Jenkins AB, Campbell LV, Freund J, Chisholm DJ: Abdominal fat and insulin resistance in normal and overweight women: direct measurements reveal a strong relationship in subjects at both low and high risk of NIDDM. Diabetes 45:633-638, 1996
-
(1996)
Diabetes
, vol.45
, pp. 633-638
-
-
Carey, D.G.1
Jenkins, A.B.2
Campbell, L.V.3
Freund, J.4
Chisholm, D.J.5
-
4
-
-
0026468362
-
What if Minkowski had been ageusic? An alternative angle on diabetes
-
McGarry JD: What if Minkowski had been ageusic? An alternative angle on diabetes. Science 258:766-770, 1992
-
(1992)
Science
, vol.258
, pp. 766-770
-
-
McGarry, J.D.1
-
5
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
Alessi DR, Andjelkovic M, Caudwell B. Cron P, Morrice N, Cohen P, Hemmings BA: Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J 15:6541-6551, 1996
-
(1996)
EMBO J
, vol.15
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovic, M.2
Caudwell, B.3
Cron, P.4
Morrice, N.5
Cohen, P.6
Hemmings, B.A.7
-
6
-
-
0034708482
-
Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site
-
Toker A, Newton AC: Akt/protein kinase B is regulated by autophosphorylation at the hypothetical PDK-2 site. J Biol Chem 275:8271-8274, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 8271-8274
-
-
Toker, A.1
Newton, A.C.2
-
7
-
-
0030984321
-
New insights into the role and mechanism of glycogen synthase activation by insulin
-
Lawrence JC Jr, Roach PJ: New insights into the role and mechanism of glycogen synthase activation by insulin. Diabetes 46:541-547, 1997
-
(1997)
Diabetes
, vol.46
, pp. 541-547
-
-
Lawrence J.C., Jr.1
Roach, P.J.2
-
8
-
-
0033588253
-
Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate
-
Schmitz-Peiffer C, Craig DL, Biden TJ: Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate. J Biol Chem 274:24202-24210, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 24202-24210
-
-
Schmitz-Peiffer, C.1
Craig, D.L.2
Biden, T.J.3
-
9
-
-
0031841949
-
Regulation of insulin-stimulated glucose transporter glut4 translocation and akt kinase activity by ceramide
-
Summers SA, Garza LA, Zhou HL, Birnbaum MJ: Regulation of insulin-stimulated glucose transporter glut4 translocation and akt kinase activity by ceramide. Mol Cell Biol 18:5457-5464, 1998
-
(1998)
Mol Cell Biol
, vol.18
, pp. 5457-5464
-
-
Summers, S.A.1
Garza, L.A.2
Zhou, H.L.3
Birnbaum, M.J.4
-
10
-
-
0032569026
-
Inhibition of akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis
-
Zhou HL, Summers SK, Birnbaum MJ, Pittman RN: Inhibition of akt kinase by cell-permeable ceramide and its implications for ceramide-induced apoptosis. J Biol Chem 273:16568-16575, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 16568-16575
-
-
Zhou, H.L.1
Summers, S.K.2
Birnbaum, M.J.3
Pittman, R.N.4
-
11
-
-
0342980927
-
Inhibition of PKB/Aktl by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells
-
Saunas M, Lopez-Valdaliso R, Martin D, Alvarez A, Cuadrado A: Inhibition of PKB/Aktl by C2-ceramide involves activation of ceramide-activated protein phosphatase in PC12 cells. Mol Cell Neurosci 15:156-169, 2000
-
(2000)
Mol Cell Neurosci
, vol.15
, pp. 156-169
-
-
Saunas, M.1
Lopez-Valdaliso, R.2
Martin, D.3
Alvarez, A.4
Cuadrado, A.5
-
12
-
-
0034607914
-
Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473
-
Schubert KM, Scheid MP, Duronio V: Ceramide inhibits protein kinase B/Akt by promoting dephosphorylation of serine 473. J Blol Chem 275: 13330-13335, 2000
-
(2000)
J Blol Chem
, vol.275
, pp. 13330-13335
-
-
Schubert, K.M.1
Scheid, M.P.2
Duronio, V.3
-
13
-
-
0025283928
-
An update of the enzymology and regulation of sphingomyelin metabolism
-
Merrill A Jr, Jones DD: An update of the enzymology and regulation of sphingomyelin metabolism. Biochim Biophys Acta 1044:1-12, 1990
-
(1990)
Biochim Biophys Acta
, vol.1044
, pp. 1-12
-
-
Merrill A., Jr.1
Jones, D.D.2
-
14
-
-
0028953260
-
Evidence that ceramide selectively inhibits protein kinase C-alpha translocation and modulates bradykinin activation of phospholipase D
-
Jones MJ, Murray AW: Evidence that ceramide selectively inhibits protein kinase C-alpha translocation and modulates bradykinin activation of phospholipase D. J Biol Chem 270:5007-5013, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 5007-5013
-
-
Jones, M.J.1
Murray, A.W.2
-
15
-
-
0029003788
-
PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid
-
Muller G, Ayoub M, Storz P, Rennecke J, Fabbro D, Pfizenmaier K: PKC zeta is a molecular switch in signal transduction of TNF-alpha, bifunctionally regulated by ceramide and arachidonic acid. EMBO J 14:1961-1969, 1995
-
(1995)
EMBO J
, vol.14
, pp. 1961-1969
-
-
Muller, G.1
Ayoub, M.2
Storz, P.3
Rennecke, J.4
Fabbro, D.5
Pfizenmaier, K.6
-
16
-
-
0032514649
-
Selective ceranude binding to protein kinase c-alpha and -delta isoenzymes in renal mesangial cells
-
Huwiler A, Fabbro D, Pfeilschifter J: Selective ceranude binding to protein kinase c-alpha and -delta isoenzymes in renal mesangial cells. Biochemistry 37:14556-14562, 1998
-
(1998)
Biochemistry
, vol.37
, pp. 14556-14562
-
-
Huwiler, A.1
Fabbro, D.2
Pfeilschifter, J.3
-
17
-
-
0027994349
-
The sphingomyelin cycle and the second messenger function of ceramide
-
Hannun YA: The sphingomyelin cycle and the second messenger function of ceramide. J Biol Chem 269:3125-3128, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 3125-3128
-
-
Hannun, Y.A.1
-
18
-
-
0029073053
-
The dimeric and catalytic subunit forms of protein phosphatase 2A from rat brain are stimulated by C2-ceramide
-
Law B, Rossie S: The dimeric and catalytic subunit forms of protein phosphatase 2A from rat brain are stimulated by C2-ceramide. J Biol Chem 270:12808-12813, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 12808-12813
-
-
Law, B.1
Rossie, S.2
-
19
-
-
0033605420
-
Protein kinase C zeta is a negative regulator of protein kinase B activity
-
Doornbos RP, Theelen M, van dHP, van Blitterswijk WJ, Verkleij AJ, Henegouwen P: Protein kinase C zeta is a negative regulator of protein kinase B activity. J Biol Chem 274:8589-8596, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 8589-8596
-
-
Doornbos, R.P.1
Van Theelen, M.D.H.P.2
Van Blitterswijk, W.J.3
Verkleij, A.J.4
Henegouwen, P.5
-
20
-
-
0034533061
-
Inhibition of growth-factor-induced phosphorylation and activation of protein kinase B/Akt by atypical protein kinase C in breast cancer cells
-
Mao ML, Fang XJ, Lu YL, LaPushin R, Bast RC, Mills GB: Inhibition of growth-factor-induced phosphorylation and activation of protein kinase B/Akt by atypical protein kinase C in breast cancer cells. Biochem J 352:475-482, 2000
-
(2000)
Biochem J
, vol.352
, pp. 475-482
-
-
Mao, M.L.1
Fang, X.J.2
Lu, Y.L.3
LaPushin, R.4
Bast, R.C.5
Mills, G.B.6
-
21
-
-
0029942186
-
Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors
-
Andjelkovic M, Jakubowicz T, Cron P, Ming XF, Han JW, Hemmings BA: Activation and phosphorylation of a pleckstrin homology domain containing protein kinase (RAC-PK/PKB) promoted by serum and protein phosphatase inhibitors. Proc Natl Acad Sci USA 93:5699-5704, 1996
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5699-5704
-
-
Andjelkovic, M.1
Jakubowicz, T.2
Cron, P.3
Ming, X.F.4
Han, J.W.5
Hemmings, B.A.6
-
22
-
-
0027178812
-
Protein kinase-C-zeta isoform is critical for mitogenic signal transduction
-
Berra E, Diazmeco MT, Dominguez I, Municio MM, Sanz L, Lozano J, Chapkin RS, Moscat J: Protein kinase-C-zeta isoform is critical for mitogenic signal transduction. Cell 74:555-563, 1993
-
(1993)
Cell
, vol.74
, pp. 555-563
-
-
Berra, E.1
Diazmeco, M.T.2
Dominguez, I.3
Municio, M.M.4
Sanz, L.5
Lozano, J.6
Chapkin, R.S.7
Moscat, J.8
-
23
-
-
0027295420
-
A dominant negative protein kinase C zeta subspecies blocks NF-kappa B activation
-
Diaz-Meco MT, Berra E, Municio MM, Sanz L, Lozano J, Dominguez I, Diaz-Golpe V, Lain de Lera MT, Alcami J, Paya CV: A dominant negative protein kinase C zeta subspecies blocks NF-kappa B activation. Mol Cell Biol 13:4770-4775, 1993
-
(1993)
Mol Cell Biol
, vol.13
, pp. 4770-4775
-
-
Diaz-Meco, M.T.1
Berra, E.2
Municio, M.M.3
Sanz, L.4
Lozano, J.5
Dominguez, I.6
Diaz-Golpe, V.7
De Lain Lera, M.T.8
Alcami, J.9
Paya, C.V.10
-
24
-
-
0002025785
-
Manipulation of adenovirus vectors gene transfer and expression protocols
-
Murray EJ, Ed. Clifton, NJ, Humana Press
-
Graham FL, Provec L: Manipulation of adenovirus vectors gene transfer and expression protocols. In Methods in Molecular Biology. Murray EJ, Ed. Clifton, NJ, Humana Press, 1991, p. 109-128
-
(1991)
Methods in Molecular Biology
, pp. 109-128
-
-
Graham, F.L.1
Provec, L.2
-
25
-
-
15644381754
-
Role of translocation in the activation and function of protein kinase B
-
Andejelkovic M, Alessi DR, Meier R, Fernandez A, Lamb N, Frech M, Cron P, Cohen P, Lucocq JM, Hemmings BA: Role of translocation in the activation and function of protein kinase B. J Biol Chem 272:31515-31524, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 31515-31524
-
-
Andejelkovic, M.1
Alessi, D.R.2
Meier, R.3
Fernandez, A.4
Lamb, N.5
Frech, M.6
Cron, P.7
Cohen, P.8
Lucocq, J.M.9
Hemmings, B.A.10
-
26
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
He TC, Zhou S, da Costa LT, Yu J, Kinzler KW, Vogelstein B: A simplified system for generating recombinant adenoviruses. Proc Natl Acad Sci U S A 95:2509-2514, 1998
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 2509-2514
-
-
He, T.C.1
Zhou, S.2
Da Costa, L.T.3
Yu, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
27
-
-
0030812546
-
Evidence for involvement of protein kinase C (PKC)-zeta and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes
-
Bandyopadhyay G, Standaert ML, Galloway L, Moscat J, Farese RV: Evidence for involvement of protein kinase C (PKC)-zeta and noninvolvement of diacylglycerol-sensitive PKCs in insulin-stimulated glucose transport in L6 myotubes. Endocrinology 138:4721-4731, 1997
-
(1997)
Endocrinology
, vol.138
, pp. 4721-4731
-
-
Bandyopadhyay, G.1
Standaert, M.L.2
Galloway, L.3
Moscat, J.4
Farese, R.V.5
-
28
-
-
0025157179
-
An investigation of the substrate specificity of protein phosphatase 2C using synthetic peptide substrates; comparison with protein phosphatase 2A
-
Donella Deana A, Mac Gowan CH, Cohen P, Marchiori F, Meyer HE, Pinna LA: An investigation of the substrate specificity of protein phosphatase 2C using synthetic peptide substrates; comparison with protein phosphatase 2A. Biochim Biophys Acta 1051:199-202, 1990
-
(1990)
Biochim Biophys Acta
, vol.1051
, pp. 199-202
-
-
Donella Deana, A.1
Mac Gowan, C.H.2
Cohen, P.3
Marchiori, F.4
Meyer, H.E.5
Pinna, L.A.6
-
29
-
-
0027143725
-
Protein serine/threonine phosphatases: Structure, regulation, and functions in cell growth
-
Mumby MC, Walter G: Protein serine/threonine phosphatases: structure, regulation, and functions in cell growth. Physiol Rev 73:673-699, 1993
-
(1993)
Physiol Rev
, vol.73
, pp. 673-699
-
-
Mumby, M.C.1
Walter, G.2
-
30
-
-
0017184389
-
A rapid and sensitive method for the quantitatiun of microgram quantities of protein utilizing the principle of protein-dye binding
-
Bradford MM: A rapid and sensitive method for the quantitatiun of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72:248-254, 1976
-
(1976)
Anal Biochem
, vol.72
, pp. 248-254
-
-
Bradford, M.M.1
-
31
-
-
0025953404
-
Use of okadaic acid to inhibit protein phosphatases in intact cells
-
Hardie DG, Haystead TA, Sim AT: Use of okadaic acid to inhibit protein phosphatases in intact cells. Methods Enzymol 201:469-476, 1991
-
(1991)
Methods Enzymol
, vol.201
, pp. 469-476
-
-
Hardie, D.G.1
Haystead, T.A.2
Sim, A.T.3
-
32
-
-
0033081893
-
Atypical PKC zeta is activated by ceramide, resulting in coactivation of NF-kappa B/JNK kinase and cell survival
-
Wang YM, Seibenhener ML, Vandenplas ML, Woolen MW: Atypical PKC zeta is activated by ceramide, resulting in coactivation of NF-kappa B/JNK kinase and cell survival. J Neurosci Res 55:293-302, 1999
-
(1999)
J Neurosci Res
, vol.55
, pp. 293-302
-
-
Wang, Y.M.1
Seibenhener, M.L.2
Vandenplas, M.L.3
Woolen, M.W.4
-
33
-
-
0034634596
-
Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex
-
Bourbon NA, Yun J, Kester M: Ceramide directly activates protein kinase C zeta to regulate a stress-activated protein kinase signaling complex. J Biol Chem 275:35617-35623, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 35617-35623
-
-
Bourbon, N.A.1
Yun, J.2
Kester, M.3
-
34
-
-
0027965006
-
Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase
-
Lozano J, Berra E, Municio MM, Diazmeco MT, Dominguez I, Sanz L, Moscat J: Protein kinase C zeta isoform is critical for kappa B-dependent promoter activation by sphingomyelinase. J Biol Chem 269:19200-19202, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 19200-19202
-
-
Lozano, J.1
Berra, E.2
Municio, M.M.3
Diazmeco, M.T.4
Dominguez, I.5
Sanz, L.6
Moscat, J.7
-
35
-
-
0030714161
-
Carboxymethylation of nuclear protein serine/threonine phosphatase X
-
Kloeker S, Bryant JC, Strack S, Colbran RJ, Wadzinski BE: Carboxymethylation of nuclear protein serine/threonine phosphatase X. Biochem J 327:481-486, 1997
-
(1997)
Biochem J
, vol.327
, pp. 481-486
-
-
Kloeker, S.1
Bryant, J.C.2
Strack, S.3
Colbran, R.J.4
Wadzinski, B.E.5
-
36
-
-
0034192404
-
A novel 50 kDa protein forms complexes with protein phosphatase 4 and is located at centrosomal microtubule organizing centres
-
Hastie CJ, Carnegie GK, Morrice N, Cohen PT: A novel 50 kDa protein forms complexes with protein phosphatase 4 and is located at centrosomal microtubule organizing centres. Biochem J 347:845-855, 2000
-
(2000)
Biochem J
, vol.347
, pp. 845-855
-
-
Hastie, C.J.1
Carnegie, G.K.2
Morrice, N.3
Cohen, P.T.4
-
37
-
-
0031915128
-
Molecular cloning, expression, and characterization of a novel human serine/threonine protein phosphatase, PP7, that is homologous to Drosophila retinal degeneration C gene product (rdgC)
-
Huang X, Honkanen RE: Molecular cloning, expression, and characterization of a novel human serine/threonine protein phosphatase, PP7, that is homologous to Drosophila retinal degeneration C gene product (rdgC). J Biol Chem 273:1462-1468, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 1462-1468
-
-
Huang, X.1
Honkanen, R.E.2
-
38
-
-
0030928118
-
Purification of a fatty acid-stimulated protein-serine/threonine phosphatase from bovine brain and its identification as a homolog of protein phosphatase 5
-
Skinner J, Sinclair C, Romeo C, Armstrong D, Charbonneau H, Rossie S: Purification of a fatty acid-stimulated protein-serine/threonine phosphatase from bovine brain and its identification as a homolog of protein phosphatase 5. J Biol Chem 272:22464-22471, 1997
-
(1997)
J Biol Chem
, vol.272
, pp. 22464-22471
-
-
Skinner, J.1
Sinclair, C.2
Romeo, C.3
Armstrong, D.4
Charbonneau, H.5
Rossie, S.6
-
39
-
-
0031015069
-
Activation of protein phosphatase 5 by limited proteolysis or the binding of polyunsaturated fatty acids to the TPR domain
-
Chen MX, Cohen PT: Activation of protein phosphatase 5 by limited proteolysis or the binding of polyunsaturated fatty acids to the TPR domain. FEBS Lett 400:136-140, 1997
-
(1997)
FEBS Lett
, vol.400
, pp. 136-140
-
-
Chen, M.X.1
Cohen, P.T.2
-
40
-
-
0033575310
-
Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A: Activation is stereospecific and regulated by phosphatidic acid
-
Chalfant CE, Kishikawa K, Mumby MC, Kamibayashi C, Bielawska A, Hannun YA: Long chain ceramides activate protein phosphatase-1 and protein phosphatase-2A: activation is stereospecific and regulated by phosphatidic acid. J Biol Chem 274:20313-20317, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 20313-20317
-
-
Chalfant, C.E.1
Kishikawa, K.2
Mumby, M.C.3
Kamibayashi, C.4
Bielawska, A.5
Hannun, Y.A.6
-
41
-
-
0029131895
-
Mitogen-artivated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin
-
Lazar DF, Wiese RJ, Brady MJ, Mastick CC, Waters SB, Yamauchi K, Pessin JE, Cuatrecasas P, Saltiel AR: Mitogen-artivated protein kinase kinase inhibition does not block the stimulation of glucose utilization by insulin. J Biol Chem 270:20801-20807, 1995
-
(1995)
J Biol Chem
, vol.270
, pp. 20801-20807
-
-
Lazar, D.F.1
Wiese, R.J.2
Brady, M.J.3
Mastick, C.C.4
Waters, S.B.5
Yamauchi, K.6
Pessin, J.E.7
Cuatrecasas, P.8
Saltiel, A.R.9
-
42
-
-
0029830346
-
Jun N-terminal kinase mediates activation of skeletal muscle glycogen synthase by insulin in vivo
-
Moxham CM, Tabrizchi A, Davis RJ, Malbon CC: Jun N-terminal kinase mediates activation of skeletal muscle glycogen synthase by insulin in vivo. J Biol Chem 271:30765-30773, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 30765-30773
-
-
Moxham, C.M.1
Tabrizchi, A.2
Davis, R.J.3
Malbon, C.C.4
-
43
-
-
0025898450
-
Identification, purification, and characterization of a novel serine/threonine protein phosphatase from bovine brain
-
Honkanen RE, Zwiller J, Daily SL, Khatra BS, Dukelow M, Boynton AL: Identification, purification, and characterization of a novel serine/threonine protein phosphatase from bovine brain. J Biol Chem 266:6614-6619, 1991
-
(1991)
J Biol Chem
, vol.266
, pp. 6614-6619
-
-
Honkanen, R.E.1
Zwiller, J.2
Daily, S.L.3
Khatra, B.S.4
Dukelow, M.5
Boynton, A.L.6
-
44
-
-
0034009389
-
Protein phosphatase 2A: A panoply of enzymes
-
Virshup DM: Protein phosphatase 2A: a panoply of enzymes (Review). Curr-Opin Cell Biol 12:180-185, 2000
-
(2000)
Curr-Opin Cell Biol
, vol.12
, pp. 180-185
-
-
Virshup, D.M.1
-
45
-
-
0029856725
-
cAMP counter-regulates insulin-mediated protein phosphatase-2A inactivation in rat skeletal muscle cells
-
Begum N, Ragolia L: cAMP counter-regulates insulin-mediated protein phosphatase-2A inactivation in rat skeletal muscle cells. J Biol Chem 271:31166-31171, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 31166-31171
-
-
Begum, N.1
Ragolia, L.2
-
46
-
-
0031953590
-
Protein phosphatase-1 and insulin action
-
Ragolia L, Begum N: Protein phosphatase-1 and insulin action. Mol Cell Biochem 182:49-58, 1998
-
(1998)
Mol Cell Biochem
, vol.182
, pp. 49-58
-
-
Ragolia, L.1
Begum, N.2
-
47
-
-
0026786471
-
Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation
-
Chen J, Martin BL, Brautigan DL: Regulation of protein serine-threonine phosphatase type-2A by tyrosine phosphorylation. Science 257:1261-1264, 1992
-
(1992)
Science
, vol.257
, pp. 1261-1264
-
-
Chen, J.1
Martin, B.L.2
Brautigan, D.L.3
-
48
-
-
0033572997
-
Role of Janus kinase-2 in insulin-mediated phosphorylation and inactivation of protein phosphatase-2A and its impact on upstream insulin signalling components
-
Begum N, Ragolia L: Role of Janus kinase-2 in insulin-mediated phosphorylation and inactivation of protein phosphatase-2A and its impact on upstream insulin signalling components. Biochem J 344:895-901, 1999
-
(1999)
Biochem J
, vol.344
, pp. 895-901
-
-
Begum, N.1
Ragolia, L.2
-
49
-
-
0033551234
-
Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycin-associated protein
-
Peterson RT, Desai BN, Hardwick JS, Schreiber SL: Protein phosphatase 2A interacts with the 70-kDa S6 kinase and is activated by inhibition of FKBP12-rapamycin-associated protein. Proc Natl Acad Sci U S A 96:4438-4442, 1999
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 4438-4442
-
-
Peterson, R.T.1
Desai, B.N.2
Hardwick, J.S.3
Schreiber, S.L.4
-
50
-
-
0032535490
-
Inactivation and dephosphorylation of protein kinase B alpha (PKB alpha) promoted by hyperosmotic stress
-
Meier R, Thelen M, Hemmings BA: Inactivation and dephosphorylation of protein kinase B alpha (PKB alpha) promoted by hyperosmotic stress. EMBO J 17:7294-7303, 1998
-
(1998)
EMBO J
, vol.17
, pp. 7294-7303
-
-
Meier, R.1
Thelen, M.2
Hemmings, B.A.3
-
51
-
-
0033178807
-
Phosphorylation and activation of phosphodiesterase type 3B (PDE3B) in adipocytes in response to serine/threonine phosphatase inhibitors: Deactivation of PDE3B in vitro by protein phosphatase type 2A
-
Resjo S, Oknianska A, Zolnierowicz S, Manganiello V, Degerman E: Phosphorylation and activation of phosphodiesterase type 3B (PDE3B) in adipocytes in response to serine/threonine phosphatase inhibitors: deactivation of PDE3B in vitro by protein phosphatase type 2A. Biochem J 341:839-845, 1999
-
(1999)
Biochem J
, vol.341
, pp. 839-845
-
-
Resjo, S.1
Oknianska, A.2
Zolnierowicz, S.3
Manganiello, V.4
Degerman, E.5
-
52
-
-
0027202552
-
Ceramide activates heterotrimeric protein phosphatase 2A
-
Dobrowsky RT, Kamibayashi C, Mumby MC, Hannun YA: Ceramide activates heterotrimeric protein phosphatase 2A. J Biol Chem 268:15523-15530, 1993
-
(1993)
J Biol Chem
, vol.268
, pp. 15523-15530
-
-
Dobrowsky, R.T.1
Kamibayashi, C.2
Mumby, M.C.3
Hannun, Y.A.4
-
53
-
-
0028122397
-
Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction
-
Wolff RA, Dobrowsky RT, Bielawska A, Obeid LM, Hannun YA: Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction. J Biol Chem 269:19605-19609, 1994
-
(1994)
J Biol Chem
, vol.269
, pp. 19605-19609
-
-
Wolff, R.A.1
Dobrowsky, R.T.2
Bielawska, A.3
Obeid, L.M.4
Hannun, Y.A.5
-
54
-
-
0033458830
-
Targeting of PKA, PKC and protein phosphatases to cellular microdomains
-
Sim ATR, Scott JD: Targeting of PKA, PKC and protein phosphatases to cellular microdomains (Review). Cell Calcium 26:209-217, 1999
-
(1999)
Cell Calcium
, vol.26
, pp. 209-217
-
-
Sim, A.T.R.1
Scott, J.D.2
-
55
-
-
0033575320
-
Ceramide induces Bcl2 dephosphorylation via a mechanism involving mitochondrial PP2A
-
Ruvolo PP, Deng XM, Ito T, Carr BK, May WS: Ceramide induces Bcl2 dephosphorylation via a mechanism involving mitochondrial PP2A. J Biol Chem 274:20296-20300, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 20296-20300
-
-
Ruvolo, P.P.1
Deng, X.M.2
Ito, T.3
Carr, B.K.4
May, W.S.5
-
56
-
-
0034056568
-
Phosphatase activity in rat adipocytes: Effects of insulin and insulin resistance
-
Dylla SJ, Williams JP, Williford J, Hardy RW: Phosphatase activity in rat adipocytes: effects of insulin and insulin resistance. J Cell Biochem 77:445-454, 2000
-
(2000)
J Cell Biochem
, vol.77
, pp. 445-454
-
-
Dylla, S.J.1
Williams, J.P.2
Williford, J.3
Hardy, R.W.4
-
57
-
-
0031885568
-
Altered regulation of insulin signaling components in adipocytes of insulin-resistant type II diabetic Goto-Kakizaki rats
-
Begum N, Ragolia L: Altered regulation of insulin signaling components in adipocytes of insulin-resistant type II diabetic Goto-Kakizaki rats. Metabolism 47:54-62, 1998
-
(1998)
Metabolism
, vol.47
, pp. 54-62
-
-
Begum, N.1
Ragolia, L.2
-
58
-
-
0034718540
-
Modulation of Akt kinase activity by binding to Hsp90
-
Sato S, Fujita N, Tsuruo T: Modulation of Akt kinase activity by binding to Hsp90. Proc Natl Acad Sci U S A 97:10832-10837, 2000
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10832-10837
-
-
Sato, S.1
Fujita, N.2
Tsuruo, T.3
-
59
-
-
0034704141
-
Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1
-
Wick MJ, Dong LQ, Riojas RA, Ramos FJ, Liu F: Mechanism of phosphorylation of protein kinase B/Akt by a constitutively active 3-phosphoinositide-dependent protein kinase-1. J Biol Chem 275:40400-40406, 2000
-
(2000)
J Biol Chem
, vol.275
, pp. 40400-40406
-
-
Wick, M.J.1
Dong, L.Q.2
Riojas, R.A.3
Ramos, F.J.4
Liu, F.5
-
60
-
-
0035281991
-
Ceramide dissociates 3 '-phosphoinositide production from pleckstrin homology domain translocation
-
Stratford S, DeWald DB, Summers SA: Ceramide dissociates 3 '-phosphoinositide production from pleckstrin homology domain translocation. Biochem J 354:359-368, 2001
-
(2001)
Biochem J
, vol.354
, pp. 359-368
-
-
Stratford, S.1
DeWald, D.B.2
Summers, S.A.3
-
61
-
-
0035133331
-
Ceramide impairs the insulin-dependent membrane recruitment of Protein Kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells
-
Hajduch E, Balendran A, Batty IH, Litherland GJ, Blair AS, Downes CP, Hundal HS: Ceramide impairs the insulin-dependent membrane recruitment of Protein Kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells. Diabetologia 44:173-183, 2001
-
(2001)
Diabetologia
, vol.44
, pp. 173-183
-
-
Hajduch, E.1
Balendran, A.2
Batty, I.H.3
Litherland, G.J.4
Blair, A.S.5
Downes, C.P.6
Hundal, H.S.7
-
62
-
-
0029908016
-
Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation
-
Kohn AD, Summers SA, Birnbaum MJ, Roth RA: Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation. J Biol Chem 271:31372-31378, 1996
-
(1996)
J Biol Chem
, vol.271
, pp. 31372-31378
-
-
Kohn, A.D.1
Summers, S.A.2
Birnbaum, M.J.3
Roth, R.A.4
-
63
-
-
0033553415
-
Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance
-
Egawa K, Sharma PM, Nakashima N, Huang Y, Huver E, Boss GR, Olefsky JM: Membrane-targeted phosphatidylinositol 3-kinase mimics insulin actions and induces a state of cellular insulin resistance. J Biol Chem 274:14306-14314, 1999
-
(1999)
J Biol Chem
, vol.274
, pp. 14306-14314
-
-
Egawa, K.1
Sharma, P.M.2
Nakashima, N.3
Huang, Y.4
Huver, E.5
Boss, G.R.6
Olefsky, J.M.7
-
64
-
-
0032514918
-
Bad enables ceramide to signal apoptosis via ras and raf-1
-
Basu S, Bayoumy S, Zhang Y, Lozano J, Kolesnick R: Bad enables ceramide to signal apoptosis via ras and raf-1. J Biol Chem 273:30419-30426, 1998
-
(1998)
J Biol Chem
, vol.273
, pp. 30419-30426
-
-
Basu, S.1
Bayoumy, S.2
Zhang, Y.3
Lozano, J.4
Kolesnick, R.5
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