Transcription activation of myostatin by trichostatin A in differentiated C2C12 Myocytes via ASK1-MKK3/4/6-JNK and p38 mitogen-activated protein kinase pathways

Journal of Cellular Biochemistry

Volumn 111, Issue 3, 2010, Pages 564-573

  Han, Der Sheng ^a,b   Huang, Hsiang Po ^a,b   Wang, Tyng Guey ^a   Hung, Meng Yu ^a   Ke, Jia Yu ^b   Chang, Kuei Ting ^b   Chang, Hsin Yu ^b   Ho, Yu Ping ^b   Hsieh, Wei Yuan ^a   Yang, Wei Shiung ^a,b  

^a NATIONAL TAIWAN UNIVERSITY HOSPITAL   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

Author keywords

C Jun N Terminal Kinase; Histone Deacetylase; Myostatin; P38 Map Kinase; Trichostatin A

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ANISOMYCIN; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; APOPTOSIS SIGNAL REGULATING KINASE 1; DACTINOMYCIN; HISTONE DEACETYLASE INHIBITOR; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE KINASE 6; MITOGEN ACTIVATED PROTEIN KINASE P38; MYOSTATIN; TRICHOSTATIN A;

ABSENCE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL LINE; MOUSE; MUSCLE CELL; MYOBLAST; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION;

ANIMALS; ANTIFUNGAL AGENTS; CELLS, CULTURED; HYDROXAMIC ACIDS; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MAP KINASE KINASE 3; MAP KINASE KINASE 6; MAP KINASE KINASE KINASE 5; MAP KINASE KINASE KINASES; MICE; MUSCLE CELLS; MYOSTATIN; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSCRIPTIONAL ACTIVATION;

EID: 78651303072     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.22740     Document Type: Article

References (53)

1. Adams GR, Haddad F, Bodell PW, Tran PD, Baldwin KM. 2007. Combined isometric, concentric, and eccentric resistance exercise prevents unloadinginduced muscle atrophy in rats. J Appl Physiol 103:1644-1654.
2. Baumann AP, Ibebunjo C, Grasser WA, Paralkar VM. 2003. Myostatin expression in age and denervation-induced skeletal muscle atrophy. J Musculoskelet Neuronal Interact 3:8-16.
3. Bogdamovich S, Krag TOB, Barton ER, Morris LD, Whittemore LA, Ahima RS, Khurana TS. 2002. Functional improvement of dystrophic muscle by myostatin blockage. Nature 420:418-421.
4. Boutros T, Chevet E, Mtrkos P. 2008. Mitogen-activated protein (MAP) kinase/MAP kinase phosphatase regulation: Roles in cell growth, death, and cancer. Pharmacol Rev 60:261-310.
5. Cao W, Bao C, Padalko E, Lowenstein CJ. 2008. Acetylation of mitogenactivated protein kinase phosphatase-1 inhibits Toll-like receptor signaling. J Exp Med 205:1491-1503.
6. Carlson CJ, Booth FW, Gordon SE. 1999. Skeletal muscle myostatin mRNA expression is fiber-type specific and increases during hindlimb unloading. Am J Physiol Regul Integr Comp Physiol 277:R601-R606.
7. Chen YJ, Tan BCM, Cheng YY, Chen JS, Lee SC. 2009. Differential regulation of CHOP translation by phosphorylated eIF4E under stress conditions. Nucleic Acids Res 1034:1-14. DOI 10.1093/nar/gkp.
8. Dokmanovic M, Clarke C, Marks PA. 2007. Histone deacetylase inhibitors: Overview and perspectives. Mol Cancer Res 5:981-989. (Pubitemid 350080267)
9. Eddy SF, Storey KB. 2007. p38MAPK regulation of transcription factor targets in muscle and heart of the hibernating bat, Myotis lucifugus. Cell Biochem Funct 25:759-765.
10. Gonzalez-Cadavid NF, Bhasin S. 2004. Role of myostatin in metabolism. Curr Opin Clin Nutr Metab Care 7:451-457.
11. Hsieh CC, Papaconstantinou J. 2006. Thioredoxin-ASK1 complex levels regulate ROS-mediated p38 MAPK pathway activity in livers of aged and long-lived Snell dwarf mice. FASEB J 20:259-268.
12. Huang W, Zhao S, Ammanamanchi S, Brattain M, Venkatasubbarao K, Freeman JW. 2005. Trichostatin A induces transforming growth factor b type II receptor promoter activity and acetylation of Sp1 by recruitment of PCAF/p300 to a Sp1-NF-Y complex. J Biol Chem 280:10047-10054.
13. Huang Z, Chen D, Zhang K, Yu B, Chen X, Meng J. 2007. Regulation of myostatin signaling by c-Jun N-terminal kinase in C2C12 cells. Cell Signal 19:2286-2295.
14. Jeanplong F, Bass JJ, Smith HK, Kirk SP, Kambadur R, Sharma M, Oldham JM. 2003. Prolonged underfeeding of sheep increases myostatin and myogenic regulatory factor Myf-5 in skeletal muscle while IGF-1 and myogenin are repressed. J Endocrinol 176:425-437.
15. Kawada S, Tachi C, Ishii N. 2001. Content and localization of myostatin in mouse skeletal muscles during aging, mechanical unloading and reloading. J Mus Res Cell Motil 22:627-633.
16. Keyse SM. 1998. Protein phosphatases and the regulation of MAP kinase activity. Semin Cell Dev Biol 9:143-152.
17. Khurana A, Dey CS. 2002. Subtype specific roles of mitogen activated protein kinases in L6E9 skeletal muscle cell differentiation. Mol Cell Biochem 238:27-39.
18. Kopple JD, Wang H, Casaburi R, Fournier M, Lewis MI, Taylor W, Storer TW. 2007. Exercise in maintenance hemodialysis patients induces transcriptional changes in genes favoring anabolic muscle. J Am Soc Nephrol 18:2975-2986.
19. Lalani R, Bhasin S, Byhower F, Tarnuzzer R, Grant M, Shen R, Asa S, Ezzat S, Gonzalez-Cadavid NF. 2000. Myostatin and insulin-like growth factor-I and -II expression in the muscle of rats exposed to the microgravity environment of the NeuroLab space shuttle flight. J Endocrinol 167:417-428.
20. Lang CH, Silvis C, Nystrom G, Frost RA. 2001. Regulation of myostatin by glucocorticoids after thermal injury. FASEB J 15:1807-1809.
21. Langley B, Thomas M, McFarlane C, Gilmour S, Sharma M, Kambadur R.2004. Myostatin inhibits rhabdomyosarcoma cell proliferation through an Rb-independent pathway. Oncogene 23:524-534.
22. Le Grand F, Rudnicki M. 2007. Satellite and stem cells in muscle growth and repair. Development 134:3953-3957. (Pubitemid 350269412)
23. Lee BI, Park SH, Kim JW, Sausville EA, Kim HT, Nakanishi O, Trepel JB, Kim SJ. 2001. MS-275, a histone deacetylase inhibitor, selectively induces transforming growth factor beta type II receptor expression in human breast cancer cells. Cancer Res 61:931-934.
24. Lee SJ, McPherron AC. 1999. Myostatin and the control of skeletal muscle mass. Curr Opin Genet Dev 9:604-607.
25. Lin J, Della-Fera MA, Li C, Page K, Chio YH, Hartzell DL, Baile CA. 2003. P27 knockout mice: Reduced myostatin in muscle and altered adipogenesis. Biochem Biophys Res Commun 300:938-942.
26. Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2-DDCT Method. Methods 25:402-408.
27. Ma K, Mallids C, Artaza J, Taylor W, Gonzalez-Cadavid N, Bhasin S. 2001. Characterization of 5'-regulatory region of human myostatin gene: Regulation by dexamethasone in vitro. Am J Physiol Endocrinol Metab 281:E1128-E1136.
28. Mal A, Sturniolo M, Schiltz RL, Ghosh MK, Harter ML. 2001. A role for histone deacetylase HDAC1 in modulating the transcriptional activity of MyoD: Inhibition of the myogenic program. EMBO 20:1739-1753.
29. Manceau M, Gros J, Savage K, Thome V, McPherron A, Paterson B, Marcelle C. 2008. Myostatin promotes the terminal differentiation of embryonic muscle progenitors. Genes Dev 22:668-681.
30. Matsuzawa A, Saegusa K, Noguchi T, Sadamitsu C, Nishitoh H, Nagai S, Koyasu S, Matsumoto K, Takeda K, Ichijo H. 2005. ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity. Nat Immunol 6:587-592.
31. McKinsey TA, Zhang CL, Olson EN. 2001. Control of muscle development by dueling HATs and HDACs. Curr Opin Genet Dev 11:497-504.
32. McPherron AC, Lawler AM, Lee SJ. 1997. Regulation of skeletal muscle mass in mice by a new TGF-b superfamily member. Nature 387:83-90.
33. Philip B, Lu Z, Gao Y. 2005. Regulation of GDF-8 signaling by the p38 MAPK. Cell Signal 17:365-375.
34. Saitoh M, Nishitoh H, Fujii M, Takeda K, Tobiume K, Sawada Y, Kawabata M, Miyazono K, Ichijo H. 1998. Mammalian thioredoxin is a direct inhibitor of apoptosis signal-regulating kinase (ASK) 1. EMBO J 17:2596-2606.
35. Sangerman J, Lee MS, Yao X, Oteng E, Hsiao CH, Li W, Zein S, Ofori-Acquah SF, Pace BS. 2006. Mechanism for fetal hemoglobin induction by histone deacetylase inhibitors involves g-globin activation by CREB1 and ATF-2. Blood 108:3590-3599.
36. Schug J, Overton GC. 1997. TESS: Transcription Element Search Software on the WWW. Technical Report CBIL-TR-1997-1001-v0.0. Computational Biology and Informatics Laboratory, School of Medicine, University of Pennsylvania.
37. Shifrin VI, Anderson P. 1999. Trichothecene mycotoxins trigger a ribotoxic stress response that activates c-Jun N-terminal kinase and p38 mitogenactivated protein kinase and induces apoptosis. J Biol Chem 274:13985-13992.
38. Shyu KG, Ko WH, Yang WS, Wang BW, Kuan P. 2005. Insulin-like growth factor-1 mediates stretch-induced upregulation of myostatin expression in neonatal rat cardiomyocytes. Cardiovasc Res 68:405-414.
39. Song S, Kang SW, Choi C. 2009. Trichostatin A enhances proliferation and migration of vascular smooth muscle cells by downregulating thioredoxin 1. Cardiovasc Res 85:241-249.
40. Spiller MP, Kambadur R, Jeanplong F, Thomas M, Martyn JK, Bass JJ, Sharma M. 2002. The myostatin gene is a downstream target gene of basic helixloop- helix transcription factor MyoD. Mol Cell Biol 22:7066-7082.
41. Tan J, Zhuang L, Jiang X, Yang KK, Karuturi KM, Yu Q. 2006. Apoptosis signal-regulating kinase 1 is a direct target of E2F1 and contributes to histone deacetylase inhibitor induced apoptosis through positive feedback regulation of E2F1 apoptotic activity. J Biol Chem 281:10508-10515.
42. Trendelenburg AU, Meyer A, Rohner D, Boyle J, Hatakeyama S, Glass DJ. 2009. Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size. Am J Physiol Cell Physiol 296:C1258-C1270.
43. Van Lint C, Emiliani S, Verdin E. 1996. The expression of a small fraction of celllular genes is changed in response to histone hyperacetylation. Gene Expr 5:245-253.
44. Witt O, Monkemeyer S, Ronndahl G, Erdlenbruch B, Reinhardt D, Kanbach K, Pekrun A. 2003. Induction of fetal hemoglobin expression by the histone deacetylase inhibitor apicidin. Blood 101:2001-2007.
45. Xiao H, Hasegawa T, Isobe K. 1999. Both Sp1 and Sp3 are responsible for p21Waf1 promoter activity induced by histone deacetylase inhibitor in NIH3T3 cells. J Cell Biochem 73:291-302.
46. Xu WS, Parmigiani RB, Marks PA. 2007. Histone deacetylase inhibitors: Molecular mechanisms of action. Oncogene 26:5541-5552.
47. YangW, Chen Y, Zhang Y,Wang X, Yang N, Zhu D. 2006. Extracellular signalregulated kinase 1/2 mitogen-activated protein kinase pathway is involved in myostatin-regulated differentiation repression. Cancer Res 66:1320-1326.
48. Zambon AC, McDearmon EL, Salomonis N, Vranizan KM, Johansen KL, Adey D, Takahashi JS, Schambelan M, Conklin BR. 2003. Time- and exercisedependent gene regulation in human skeletal muscle. Genome Biol 4:R61.1- R61.12.
49. Zhang CL, McKinsey TA, Chang S, Antos CL, Hill JA, Olson EN. 2002. Class II histone deacetylases act as signal-responsive repressors of cardiac hypertrophy. Cell 110:479-488.
50. Zhang D, Liu M, Ding F, Gu X. 2006. Expression of myostatin RNA transcript and protein in gastrocnemius muscle of rats after sciatic nerve resection. J Mus Res Cell Motil 27:37-44.
51. Zhang X, Wharton W, Yuan Z, Tsai SC, Olashaw N, Seto E. 2004. Activation of the growth-differentiatio factor 11 gene by the histone deacetlase (HDAC) inhibitor trichostatin A and repression by HDAC3. Mol Cell Biol 24:5106-51118.
52. Zhao Y, Lu S, Wu L, Chai G, Wang H, Chen Y, Sun J, Yu Y, Zhou W, Zheng Q, Wu M, Otterson GA, Zhu WG. 2006. Acetylation of p53 at lysine 373/382 by the histone deacetylase inihibitor depsipeptide induces expression of p21Waf1/Cip1. Mol Cell Biol 26:2782-2790.
53. Zimmers TA, Davies MV, Koniaris LG, Haynes P. 2002. Induction of cachexia in mice by systemically administered myostatin. Science 296:1486-1488.