메뉴 건너뛰기




Volumn 145, Issue 10, 2004, Pages 4592-4602

Proinflammatory cytokine impairment of insulin-like growth factor I-induced protein synthesis in skeletal muscle myoblasts requires ceramide

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; CERAMIDE DERIVATIVE; CYTOKINE; FUMONISIN B1; GLUTATHIONE; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1BETA; MYOD PROTEIN; MYOGENIN; SOMATOMEDIN C; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE; TRICYCLO[4.3.0.1]DECAN 9 YL XANTHOGENATE; TUMOR NECROSIS FACTOR ALPHA;

EID: 4644221064     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-1749     Document Type: Article
Times cited : (97)

References (68)
  • 1
    • 0035175162 scopus 로고    scopus 로고
    • Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth
    • Lupu F, Terwilliger JD, Lee K, Segre GV, Efstratiadis A 2001 Roles of growth hormone and insulin-like growth factor 1 in mouse postnatal growth. Dev Biol 229:141-162
    • (2001) Dev Biol , vol.229 , pp. 141-162
    • Lupu, F.1    Terwilliger, J.D.2    Lee, K.3    Segre, G.V.4    Efstratiadis, A.5
  • 2
    • 0842287527 scopus 로고    scopus 로고
    • From hormones to immunity: The physiology of immunology
    • Kelley KW 2004 From hormones to immunity: the physiology of immunology. Brain Behav Immun 18:95-113
    • (2004) Brain Behav Immun , vol.18 , pp. 95-113
    • Kelley, K.W.1
  • 3
    • 0029810374 scopus 로고    scopus 로고
    • Changes in body composition of human immunodeficiency virus-infected males receiving insulin-like growth factor I and growth hormone
    • Ellis KJ, Lee PD, Pivarnik JM, Bukar JG, Gesundheit N 1996 Changes in body composition of human immunodeficiency virus-infected males receiving insulin-like growth factor I and growth hormone. J Clin Endocrinol Metab 81:3033-3038
    • (1996) J Clin Endocrinol Metab , vol.81 , pp. 3033-3038
    • Ellis, K.J.1    Lee, P.D.2    Pivarnik, J.M.3    Bukar, J.G.4    Gesundheit, N.5
  • 6
    • 0033772110 scopus 로고    scopus 로고
    • Regulation of skeletal-muscle-protein turnover in cancer-associated cachexia
    • Baracos VE 2000 Regulation of skeletal-muscle-protein turnover in cancer-associated cachexia. Nutrition 16:1015-1018
    • (2000) Nutrition , vol.16 , pp. 1015-1018
    • Baracos, V.E.1
  • 7
    • 0036203972 scopus 로고    scopus 로고
    • Reasons for the degeneration of ageing skeletal muscle: A central role for IGF-1 signalling
    • Grounds MD 2002 Reasons for the degeneration of ageing skeletal muscle: a central role for IGF-1 signalling. Biogerontology 3:19-24
    • (2002) Biogerontology , vol.3 , pp. 19-24
    • Grounds, M.D.1
  • 8
    • 0034929020 scopus 로고    scopus 로고
    • Assessment of physical function in aging rodents: A strategy for improving preclinical testing
    • Carter CS, Pahor M, Sonntag WE 2001 Assessment of physical function in aging rodents: a strategy for improving preclinical testing. Exp Aging Res 27:271-282
    • (2001) Exp Aging Res , vol.27 , pp. 271-282
    • Carter, C.S.1    Pahor, M.2    Sonntag, W.E.3
  • 9
    • 0030924558 scopus 로고    scopus 로고
    • Transient exposure of human myoblasts to tumor necrosis factor-α inhibits serum and insulin-like growth factor-I stimulated protein synthesis
    • Frost RA, Lang CH, Gelato MC 1997 Transient exposure of human myoblasts to tumor necrosis factor-α inhibits serum and insulin-like growth factor-I stimulated protein synthesis. Endocrinology 138:4153-4159
    • (1997) Endocrinology , vol.138 , pp. 4153-4159
    • Frost, R.A.1    Lang, C.H.2    Gelato, M.C.3
  • 11
    • 0030756346 scopus 로고    scopus 로고
    • Protection from obesity-induced insulin resistance in mice lacking TNF-α function
    • Uysal KT, Wiesbrock SM, Marino MW, Hotamisligil GS 1997 Protection from obesity-induced insulin resistance in mice lacking TNF-α function. Nature 389:610-614
    • (1997) Nature , vol.389 , pp. 610-614
    • Uysal, K.T.1    Wiesbrock, S.M.2    Marino, M.W.3    Hotamisligil, G.S.4
  • 13
    • 0038721699 scopus 로고    scopus 로고
    • Cytokine-hormone interactions: Tumor necrosis factor α impairs biologic activity and downstream activation signals of the insulin-like growth factor I receptor in myoblasts
    • Broussard SR, McCusker RH, Novakofski JE, Strle K, Shen WH, Johnson RW, Freund GG, Dantzer R, Kelley KW 2003 Cytokine-hormone interactions: tumor necrosis factor α impairs biologic activity and downstream activation signals of the insulin-like growth factor I receptor in myoblasts. Endocrinology 144:2988-2996
    • (2003) Endocrinology , vol.144 , pp. 2988-2996
    • Broussard, S.R.1    McCusker, R.H.2    Novakofski, J.E.3    Strle, K.4    Shen, W.H.5    Johnson, R.W.6    Freund, G.G.7    Dantzer, R.8    Kelley, K.W.9
  • 14
    • 2942555110 scopus 로고    scopus 로고
    • IL-1β impairs insulin-like growth factor I-induced differentiation and downstream activation signals of the insulin-like growth factor I receptor in myoblasts
    • Broussard SR, McCusker RH, Novakofski JE, Strle K, Shen WH, Johnson RW, Dantzer R, Kelley KW 2004 IL-1β impairs insulin-like growth factor I-induced differentiation and downstream activation signals of the insulin-like growth factor I receptor in myoblasts. J Immunol 172:7713-7720
    • (2004) J Immunol , vol.172 , pp. 7713-7720
    • Broussard, S.R.1    McCusker, R.H.2    Novakofski, J.E.3    Strle, K.4    Shen, W.H.5    Johnson, R.W.6    Dantzer, R.7    Kelley, K.W.8
  • 16
    • 0029257376 scopus 로고
    • The MyoD family of transcription factors and skeletal myogenesis
    • Rudnicki MA, Jaenisch R1995 The MyoD family of transcription factors and skeletal myogenesis. Bioessays 17:203-209
    • (1995) Bioessays , vol.17 , pp. 203-209
    • Rudnicki, M.A.1    Jaenisch, R.2
  • 17
    • 0037102303 scopus 로고    scopus 로고
    • Proinflammatory cytokines block growth of breast cancer cells by impairing signals from a growth factor receptor
    • Shen WH, Zhou JH, Broussard SR, Freund GG, Dantzer R, Kelley KW 2002 Proinflammatory cytokines block growth of breast cancer cells by impairing signals from a growth factor receptor. Cancer Res 62:4746-4756
    • (2002) Cancer Res , vol.62 , pp. 4746-4756
    • Shen, W.H.1    Zhou, J.H.2    Broussard, S.R.3    Freund, G.G.4    Dantzer, R.5    Kelley, K.W.6
  • 18
    • 1542290024 scopus 로고    scopus 로고
    • Tumor necrosis factor α inhibits cyclin A expression and retinoblastoma hyperphosphorylation triggered by insulin-like growth factor-I induction of new E2F-1 synthesis
    • Shen WH, Yin Y, Broussard SR, McCusker RH, Freund GG, Dantzer R, Kelley KW 2004 Tumor necrosis factor α inhibits cyclin A expression and retinoblastoma hyperphosphorylation triggered by insulin-like growth factor-I induction of new E2F-1 synthesis. J Biol Chem 279:7438-7446
    • (2004) J Biol Chem , vol.279 , pp. 7438-7446
    • Shen, W.H.1    Yin, Y.2    Broussard, S.R.3    McCusker, R.H.4    Freund, G.G.5    Dantzer, R.6    Kelley, K.W.7
  • 20
    • 0035880016 scopus 로고    scopus 로고
    • Sphingomyelin and ceramide as regulators of development and lifespan
    • Cutler RG, Mattson MP 2001 Sphingomyelin and ceramide as regulators of development and lifespan. Mech Ageing Dev 122:895-908
    • (2001) Mech Ageing Dev , vol.122 , pp. 895-908
    • Cutler, R.G.1    Mattson, M.P.2
  • 21
    • 0033749620 scopus 로고    scopus 로고
    • Signalling aspects of insulin resistance in skeletal muscle: Mechanisms induced by lipid oversupply
    • Schmitz-Peiffer C 2000 Signalling aspects of insulin resistance in skeletal muscle: mechanisms induced by lipid oversupply. Cell Signal 12:583-594
    • (2000) Cell Signal , vol.12 , pp. 583-594
    • Schmitz-Peiffer, C.1
  • 22
    • 0026458406 scopus 로고
    • TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown
    • Schutze S, Potthoff K, Machleidt T, Berkovic D, Wiegmann K, Kronke M 1992 TNF activates NF-κB by phosphatidylcholine-specific phospholipase C-induced "acidic" sphingomyelin breakdown. Cell 71:765-776
    • (1992) Cell , vol.71 , pp. 765-776
    • Schutze, S.1    Potthoff, K.2    Machleidt, T.3    Berkovic, D.4    Wiegmann, K.5    Kronke, M.6
  • 23
    • 0028108015 scopus 로고
    • Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling
    • Wiegmann K, Schutze S, Machleidt T, Witte D, Kronke M 1994 Functional dichotomy of neutral and acidic sphingomyelinases in tumor necrosis factor signaling. Cell 78:1005-1015
    • (1994) Cell , vol.78 , pp. 1005-1015
    • Wiegmann, K.1    Schutze, S.2    Machleidt, T.3    Witte, D.4    Kronke, M.5
  • 26
    • 0032568836 scopus 로고    scopus 로고
    • Involvement of de novo ceramide biosynthesis in tumor necrosis factor-α/cycloheximide-induced cerebral endothelial cell death
    • Xu J, Yeh CH, Chen S, He L, Sensi SL, Canzoniero LM, Choi DW, Hsu CY 1998 Involvement of de novo ceramide biosynthesis in tumor necrosis factor-α/cycloheximide-induced cerebral endothelial cell death. J Biol Chem 273: 16521-16526
    • (1998) J Biol Chem , vol.273 , pp. 16521-16526
    • Xu, J.1    Yeh, C.H.2    Chen, S.3    He, L.4    Sensi, S.L.5    Canzoniero, L.M.6    Choi, D.W.7    Hsu, C.Y.8
  • 27
    • 0027461121 scopus 로고
    • Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1β
    • Mathias S, Younes A, Kan CC, Orlow I, Joseph C, Kolesnick RN 1993 Activation of the sphingomyelin signaling pathway in intact EL4 cells and in a cell-free system by IL-1β. Science 259:519-522
    • (1993) Science , vol.259 , pp. 519-522
    • Mathias, S.1    Younes, A.2    Kan, C.C.3    Orlow, I.4    Joseph, C.5    Kolesnick, R.N.6
  • 30
    • 0035133331 scopus 로고    scopus 로고
    • Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells
    • Hajduch E, Balendran A, Batty IH, Litherland GJ, Blair AS, Downes CP, Hundal HS 2001 Ceramide impairs the insulin-dependent membrane recruitment of protein kinase B leading to a loss in downstream signalling in L6 skeletal muscle cells. Diabetologia 44:173-183
    • (2001) Diabetologia , vol.44 , pp. 173-183
    • Hajduch, E.1    Balendran, A.2    Batty, I.H.3    Litherland, G.J.4    Blair, A.S.5    Downes, C.P.6    Hundal, H.S.7
  • 31
    • 0033588253 scopus 로고    scopus 로고
    • Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate
    • Schmitz-Peiffer C, Craig DL, Biden TJ 1999 Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate. J Biol Chem 274:24202-24210
    • (1999) J Biol Chem , vol.274 , pp. 24202-24210
    • Schmitz-Peiffer, C.1    Craig, D.L.2    Biden, T.J.3
  • 33
    • 0037020075 scopus 로고    scopus 로고
    • Sphingosine 1-phosphate triggers both apoptotic and survival signals for human hepatic myofibroblasts
    • Davaille J, Li L, Mallat A, Lotersztajn S 2002 Sphingosine 1-phosphate triggers both apoptotic and survival signals for human hepatic myofibroblasts. J Biol Chem 277:37323-37330
    • (2002) J Biol Chem , vol.277 , pp. 37323-37330
    • Davaille, J.1    Li, L.2    Mallat, A.3    Lotersztajn, S.4
  • 36
    • 0031586327 scopus 로고    scopus 로고
    • Induction of apoptosis and potentiation of TNF- and Fas-mediated apoptosis in U937 cells by the xanthogenate compound D609
    • Porn-Ares MI, Chow SC, Slotte JP, Orrenius S 1997 Induction of apoptosis and potentiation of TNF- and Fas-mediated apoptosis in U937 cells by the xanthogenate compound D609. Exp Cell Res 235:48-54
    • (1997) Exp Cell Res , vol.235 , pp. 48-54
    • Porn-Ares, M.I.1    Chow, S.C.2    Slotte, J.P.3    Orrenius, S.4
  • 37
    • 0033305623 scopus 로고    scopus 로고
    • Tumor necrosis factor-α induces apoptosis in immortalized hypothalamic neurons: Involvement of ceramide-generating pathways
    • Sortino MA, Condorelli F, Vancheri C, Canonico PL 1999 Tumor necrosis factor-α induces apoptosis in immortalized hypothalamic neurons: involvement of ceramide-generating pathways. Endocrinology 140:4841-4849
    • (1999) Endocrinology , vol.140 , pp. 4841-4849
    • Sortino, M.A.1    Condorelli, F.2    Vancheri, C.3    Canonico, P.L.4
  • 38
    • 0037160017 scopus 로고    scopus 로고
    • Apolipoprotein-mediated cellular lipid release requires replenishment of sphingomyelin in a phosphatidylcholine-specific phospholipase C-dependent manner
    • Ito J, Nagayasu Y, Ueno S, Yokoyama S 2002 Apolipoprotein-mediated cellular lipid release requires replenishment of sphingomyelin in a phosphatidylcholine-specific phospholipase C-dependent manner. J Biol Chem 277:44709-44714
    • (2002) J Biol Chem , vol.277 , pp. 44709-44714
    • Ito, J.1    Nagayasu, Y.2    Ueno, S.3    Yokoyama, S.4
  • 39
    • 0026317132 scopus 로고
    • Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme
    • Wang E, Norred WP, Bacon CW, Riley RT, Merrill Jr AH 1991 Inhibition of sphingolipid biosynthesis by fumonisins. Implications for diseases associated with Fusarium moniliforme. J Biol Chem 266:14486-14490
    • (1991) J Biol Chem , vol.266 , pp. 14486-14490
    • Wang, E.1    Norred, W.P.2    Bacon, C.W.3    Riley, R.T.4    Merrill Jr., A.H.5
  • 40
    • 0032079524 scopus 로고    scopus 로고
    • Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-α-induced cell death
    • Liu B, Andrieu-Abadie N, Levade T, Zhang P, Obeid LM, Hannun YA 1998 Glutathione regulation of neutral sphingomyelinase in tumor necrosis factor-α-induced cell death. J Biol Chem 273:11313-11320
    • (1998) J Biol Chem , vol.273 , pp. 11313-11320
    • Liu, B.1    Andrieu-Abadie, N.2    Levade, T.3    Zhang, P.4    Obeid, L.M.5    Hannun, Y.A.6
  • 41
    • 0030960327 scopus 로고    scopus 로고
    • Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione
    • Liu B, Hannun YA 1997 Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione. J Biol Chem 272:16281-16287
    • (1997) J Biol Chem , vol.272 , pp. 16281-16287
    • Liu, B.1    Hannun, Y.A.2
  • 42
    • 0026323465 scopus 로고
    • Mechanically induced alterations in cultured skeletal muscle growth
    • Vandenburgh HH, Hatfaludy S, Karlisch P, Shansky J 1991 Mechanically induced alterations in cultured skeletal muscle growth. J Biomech 24(Suppl 1):91-99
    • (1991) J Biomech , vol.24 , Issue.1 SUPPL. , pp. 91-99
    • Vandenburgh, H.H.1    Hatfaludy, S.2    Karlisch, P.3    Shansky, J.4
  • 43
    • 4644270209 scopus 로고    scopus 로고
    • Cary, NC: SAS Institute
    • SAS 2003 User's guide. Version 8.2. Cary, NC: SAS Institute
    • (2003) User's Guide. Version 8.2
  • 44
    • 0029933665 scopus 로고    scopus 로고
    • Tumor necrosis factor (TNF)-α inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase
    • Peraldi P, Hotamisligil GS, Buurman WA, White MF, Spiegelman BM 1996 Tumor necrosis factor (TNF)-α inhibits insulin signaling through stimulation of the p55 TNF receptor and activation of sphingomyelinase. J Biol Chem 271:13018-13022
    • (1996) J Biol Chem , vol.271 , pp. 13018-13022
    • Peraldi, P.1    Hotamisligil, G.S.2    Buurman, W.A.3    White, M.F.4    Spiegelman, B.M.5
  • 45
    • 0029874429 scopus 로고    scopus 로고
    • Sphingomyelinase and ceramide suppress insulin-induced tyrosine phosphorylation of the insulin receptor substrate-1
    • Kanety H, Hemi R, Papa MZ, Karasik A1996 Sphingomyelinase and ceramide suppress insulin-induced tyrosine phosphorylation of the insulin receptor substrate-1. J Biol Chem 271:9895-9897
    • (1996) J Biol Chem , vol.271 , pp. 9895-9897
    • Kanety, H.1    Hemi, R.2    Papa, M.Z.3    Karasik, A.4
  • 46
    • 0038532298 scopus 로고    scopus 로고
    • A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids
    • Chavez JA, Knotts TA, Wang LP, Li G, Dobrowsky RT, Florant GL, Summers SA 2003 A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids. J Biol Chem 278:10297-10303
    • (2003) J Biol Chem , vol.278 , pp. 10297-10303
    • Chavez, J.A.1    Knotts, T.A.2    Wang, L.P.3    Li, G.4    Dobrowsky, R.T.5    Florant, G.L.6    Summers, S.A.7
  • 47
    • 0036479251 scopus 로고    scopus 로고
    • Ceramide-induced inhibition of Akt is mediated through protein kinase Cζ: Implications for growth arrest
    • Bourbon NA, Sandirasegarane L, Kester M 2002 Ceramide-induced inhibition of Akt is mediated through protein kinase Cζ: implications for growth arrest. J Biol Chem 277:3286-3292
    • (2002) J Biol Chem , vol.277 , pp. 3286-3292
    • Bourbon, N.A.1    Sandirasegarane, L.2    Kester, M.3
  • 49
    • 0033602762 scopus 로고    scopus 로고
    • Tumor necrosis factor-α and basic fibroblast growth factor differentially inhibit the insulin-like growth factor-I induced expression of myogenin in C2C12 myoblasts
    • Layne MD, Farmer SR 1999 Tumor necrosis factor-α and basic fibroblast growth factor differentially inhibit the insulin-like growth factor-I induced expression of myogenin in C2C12 myoblasts. Exp Cell Res 249:177-187
    • (1999) Exp Cell Res , vol.249 , pp. 177-187
    • Layne, M.D.1    Farmer, S.R.2
  • 50
    • 0028076002 scopus 로고
    • The role of diacylglycerol and ceramide in tumor necrosis factor and interleukin-1 signal transduction
    • Schutze S, Machleidt T, Kronke M 1994 The role of diacylglycerol and ceramide in tumor necrosis factor and interleukin-1 signal transduction. J Leukoc Biol 56:533-541
    • (1994) J Leukoc Biol , vol.56 , pp. 533-541
    • Schutze, S.1    Machleidt, T.2    Kronke, M.3
  • 51
    • 0029040848 scopus 로고
    • Myogenic vector expression of insulin-like growth factor 1 stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice
    • Coleman ME, DeMayo F, Yin KC, Lee HM, Geske R, Montgomery C, Schwartz RJ 1995 Myogenic vector expression of insulin-like growth factor 1 stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice. J Biol Chem 270:12109-12116
    • (1995) J Biol Chem , vol.270 , pp. 12109-12116
    • Coleman, M.E.1    DeMayo, F.2    Yin, K.C.3    Lee, H.M.4    Geske, R.5    Montgomery, C.6    Schwartz, R.J.7
  • 52
    • 0025836395 scopus 로고
    • Insulin-like growth factor-I stimulates terminal myogenic differentiation by induction of myogenin gene expression
    • Florini JR, Ewton DZ, Roof SL 1991 Insulin-like growth factor-I stimulates terminal myogenic differentiation by induction of myogenin gene expression. Mol Endocrinol 5:718-724
    • (1991) Mol Endocrinol , vol.5 , pp. 718-724
    • Florini, J.R.1    Ewton, D.Z.2    Roof, S.L.3
  • 53
    • 0030736776 scopus 로고    scopus 로고
    • Activation of acid sphingomyelinase by interleukin-1 (IL-1) requires the IL-1 receptor accessory protein
    • Hofmeister R, Wiegmann K, Korherr C, Bernardo K, Kronke M, Falk W 1997 Activation of acid sphingomyelinase by interleukin-1 (IL-1) requires the IL-1 receptor accessory protein. J Biol Chem 272:27730-27736
    • (1997) J Biol Chem , vol.272 , pp. 27730-27736
    • Hofmeister, R.1    Wiegmann, K.2    Korherr, C.3    Bernardo, K.4    Kronke, M.5    Falk, W.6
  • 55
    • 0347122965 scopus 로고    scopus 로고
    • Amyloid-β peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway
    • Lee JT, Xu J, Lee JM, Ku G, Han X Yang DI, Chen S, Hsu CY 2004 Amyloid-β peptide induces oligodendrocyte death by activating the neutral sphingomyelinase-ceramide pathway. J Cell Biol 164:123-131
    • (2004) J Cell Biol , vol.164 , pp. 123-131
    • Lee, J.T.1    Xu, J.2    Lee, J.M.3    Ku, G.4    Han, X.5    Yang, D.I.6    Chen, S.7    Hsu, C.Y.8
  • 57
    • 0035955295 scopus 로고    scopus 로고
    • TNFα-induced glutathione depletion lies downstream of cPLA(2) in L929 cells
    • Hayter HL, Pettus BJ, Ito F, Obeid LM, Hannun YA 2001 TNFα-induced glutathione depletion lies downstream of cPLA(2) in L929 cells. FEBS Lett 507:151-156
    • (2001) FEBS Lett , vol.507 , pp. 151-156
    • Hayter, H.L.1    Pettus, B.J.2    Ito, F.3    Obeid, L.M.4    Hannun, Y.A.5
  • 58
    • 0345304238 scopus 로고    scopus 로고
    • Crocin prevents the death of PC-12 cells through sphingomyelinase- ceramide signaling by increasing glutathione synthesis
    • Ochiai T, Soeda S, Ohno S, Tanaka H, Shoyama Y, Shimeno H 2004 Crocin prevents the death of PC-12 cells through sphingomyelinase-ceramide signaling by increasing glutathione synthesis. Neurochem Int 44:321-330
    • (2004) Neurochem Int , vol.44 , pp. 321-330
    • Ochiai, T.1    Soeda, S.2    Ohno, S.3    Tanaka, H.4    Shoyama, Y.5    Shimeno, H.6
  • 59
    • 0033958975 scopus 로고    scopus 로고
    • Synergistic effect of β-amyloid protein and interferon γ on nitric oxide production by C2C12 muscle cells
    • Baron P, Galimberti D, Meda L, Prat E, Scarpini E, Conti G, Moggio M, Prelle A, Scarlato G 2000 Synergistic effect of β-amyloid protein and interferon γ on nitric oxide production by C2C12 muscle cells. Brain 123(Pt 2):374-379
    • (2000) Brain , vol.123 , Issue.2 PART , pp. 374-379
    • Baron, P.1    Galimberti, D.2    Meda, L.3    Prat, E.4    Scarpini, E.5    Conti, G.6    Moggio, M.7    Prelle, A.8    Scarlato, G.9
  • 65
    • 0032841435 scopus 로고    scopus 로고
    • Irs-2 coordinates Igf-1 receptor-mediated β-cell development and peripheral insulin signalling
    • Withers DJ, Burks DJ, Towery HH, Altamuro SL, Flint CL, White MF 1999 Irs-2 coordinates Igf-1 receptor-mediated β-cell development and peripheral insulin signalling. Nat Genet 23:32-40
    • (1999) Nat Genet , vol.23 , pp. 32-40
    • Withers, D.J.1    Burks, D.J.2    Towery, H.H.3    Altamuro, S.L.4    Flint, C.L.5    White, M.F.6
  • 66
    • 0034097181 scopus 로고    scopus 로고
    • Tumor necrosis factor-α-induced apoptosis is associated with suppression of insulin-like growth factor binding protein-5 secretion in differentiating murine skeletal myoblasts
    • Meadows KA, Holly JM, Stewart CE 2000 Tumor necrosis factor-α- induced apoptosis is associated with suppression of insulin-like growth factor binding protein-5 secretion in differentiating murine skeletal myoblasts. J Cell Physiol 183:330-337
    • (2000) J Cell Physiol , vol.183 , pp. 330-337
    • Meadows, K.A.1    Holly, J.M.2    Stewart, C.E.3
  • 68
    • 0142039870 scopus 로고    scopus 로고
    • Autocrine growth factor signaling by insulin-like growth factor-II mediates MyoD-stimulated myocyte maturation
    • Wilson EM, Hsieh MM, Rotwein P 2003 Autocrine growth factor signaling by insulin-like growth factor-II mediates MyoD-stimulated myocyte maturation. J Biol Chem 278:41109-41113
    • (2003) J Biol Chem , vol.278 , pp. 41109-41113
    • Wilson, E.M.1    Hsieh, M.M.2    Rotwein, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.